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https://www.readbyqxmd.com/read/28323628/effects-of-bach-flower-remedies-on-menopausal-symptoms-and-sleep-pattern-a-case-report
#1
Marcele Siegler, Cristina Frange, Monica Levy Andersen, Sergio Tufik, Helena Hachul
Context • During the postmenopausal stage, women go through many remarkable changes, including physical, emotional, and hormonal. They also experience some unwanted effects, such as vasomotor symptoms, anxiety, and insomnia. The use of Bach flower remedies has been described as a supporting therapy for those symptoms. Objectives • The investigation aimed to evaluate the effects of the supplement on sleep pattern (ie, sleep perception and objective sleep) and on menopausal symptoms. Design • The research team created a case report...
March 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28315665/physician-scientists-in-obstetrics-and-gynecology-predictors-of-success-in-obtaining-independent-research-funding
#2
Ijeoma Okeigwe, Cynthia Wang, Joseph A Politch, Linda J Heffner, Wendy Kuohung
BACKGROUND: Obstetrics and gynecology departments receive the smallest amount of National Institutes of Health (NIH) research funding and have significantly lower application success rates compared to pediatric, internal medicine, and surgery departments. The development of mentored early career development training grants (K awards) has been one strategy implemented by the NIH to help aspiring physician-scientists establish independent research careers. OBJECTIVE: The purpose of this study is to describe the cohort of ob/gyn physician-scientists who were K08, K12, and K23 recipients from 1988-2015 and to identify predictors of success in obtaining independent federal funding, as defined by acquisition of an R01, R21, R34, U01, U54, P01, or P50...
March 15, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28304416/gynecologic-malignancies-in-pregnancy-balancing-fetal-risks-with-oncologic-safety
#3
Christina N Cordeiro, Mary L Gemignani
Importance: Cancer occurs in 0.05% to 0.1% of all pregnancies. Despite literature reporting good oncologic and fetal outcomes in women treated for cancer during pregnancy, as many as 44% of gynecologists would offer termination, and 37% would not administer chemotherapy or radiotherapy in pregnancy. Objectives: The aims of this study were to summarize current recommendations for the treatment of cervical and ovarian cancers in pregnancy and to review updates on existing knowledge regarding the safety of surgical and chemotherapeutic treatments in pregnancy, including both oncologic and fetal outcomes...
March 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/28292439/integrated-molecular-characterization-of-uterine-carcinosarcoma
#4
Andrew D Cherniack, Hui Shen, Vonn Walter, Chip Stewart, Bradley A Murray, Reanne Bowlby, Xin Hu, Shiyun Ling, Robert A Soslow, Russell R Broaddus, Rosemary E Zuna, Gordon Robertson, Peter W Laird, Raju Kucherlapati, Gordon B Mills, John N Weinstein, Jiashan Zhang, Rehan Akbani, Douglas A Levine
We performed genomic, epigenomic, transcriptomic, and proteomic characterizations of uterine carcinosarcomas (UCSs). Cohort samples had extensive copy-number alterations and highly recurrent somatic mutations. Frequent mutations were found in TP53, PTEN, PIK3CA, PPP2R1A, FBXW7, and KRAS, similar to endometrioid and serous uterine carcinomas. Transcriptome sequencing identified a strong epithelial-to-mesenchymal transition (EMT) gene signature in a subset of cases that was attributable to epigenetic alterations at microRNA promoters...
March 13, 2017: Cancer Cell
https://www.readbyqxmd.com/read/28287918/premenstrual-syndrome-is-associated-with-a-higher-frequency-of-female-sexual-difficulty-and-sexual-distress
#5
Gülşah İlhan, Fatma Verda Verit Atmaca, Meryem Kurek Eken, Hürkan Akyol
BACKGROUND/AIMS: Few prospective studies have evaluated the impact of premenstrual symptoms (PMS) on female sexual function and sexuality related distress. Therefore the purpose of the present study was to find out risk factors of PMS for  female sexual function and sexuality related personal distress. METHODS: This prospective cohort study was conducted at the Suleymaniye women's health and disease, research and education hospital, Istanbul, Turkey between February 2014 and March 2016...
March 13, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28286604/a-review-of-mtor-pathway-inhibitors-in-gynecologic-cancer
#6
REVIEW
Andréia Cristina de Melo, Eduardo Paulino, Álvaro Henrique Ingles Garces
The treatment of advanced gynecologic cancers remains palliative in most of cases. Although systemic treatment has entered into the era of targeted drugs the antitumor efficacies of current therapies are still limited. In this context there is a great need for more active treatment and rationally designed targeted therapies. The PI3K/AKT/mTOR is a signaling pathway in mammal cells that coordinates important cell activities. It has a critical function in the survival, growth, and proliferation of malignant cells and was object of important research in the last two decades...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28285615/consensus-on-the-integrated-traditional-chinese-and-western-medicine-criteria-of-diagnostic-classification-in-polycystic-ovary-syndrome-draft
#7
Jin Yu, Chao-Qin Yu, Qi Cao, Li Wang, Wen-Jun Wang, Li-Rong Zhou, Jing Li, Qiao-Hong Qian
Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder of women, with complex pathogenesis and heterogeneous manifestations. Professor Jin Yu recently wrote an article entitled "Proposal of Diagnosis and Diagnostic Classification of PCOS in Integrated Traditional Chinese and Western Medicine."From this, the Obstetrics and Gynecology branches of the Chinese Association of Integrative Medicine and the China Association of Chinese Medicine collaborated with the Gynecology branch of the Chinese Association for Research and Advancement of Chinese Medicine to draft a report on the consensus of criteria for the diagnosis and classification of PCOS in integrated traditional Chinese and Western medicine...
March 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28278350/the-role-of-the-vaginal-microbiome-in-gynecological-cancer-a-review
#8
REVIEW
Miriam Champer, Alexandra M Wong, Jackson Champer, Ilana L Brito, Philipp W Messer, June Y Hou, Jason D Wright
Human microbiome research has shown commensal bacteria to be a major factor in both wellness and disease pathogenesis. Interest in the microbiome has recently expanded beyond the gut to include a multitude of other organ systems for which the microbiome may have health implications. Here, we review the role of the vaginal microbiome in health and disease, with a particular focus on gynecologic malignancies. Further, we suggest that it may be possible to expand the use of probiotics in the treatment of gynecologic cancers...
March 9, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28278022/knowledge-and-attitudes-toward-female-genital-cutting-among-west-african-male-immigrants-in-new-york-city
#9
Adeyinka M Akinsulure-Smith, Tracy Chu
In this project, we explored knowledge and attitudes towards FGC in a survey of 107 West African immigrants, including 36 men. Men in this study were as knowledgeable about the health consequences of FGC as women, though with a less nuanced understanding. They also rejected the practice at rates comparable to women. Despite this knowledge and rejection of FGC, most men did not express a personal preference for women with or without FGC in intimate relationships. Future research and interventions must explore men's opposition to FGC and emphasize the impact of FGC on their partners' gynecological and reproductive health...
February 13, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28277367/executive-summary-of-the-revitalize-initiative-standardizing-gynecologic-data-definitions
#10
Howard T Sharp, Julia V Johnson, Lauren A Lemieux, Sean M Currigan
Effective care coordination across the women's health continuum is critically important. Unlike obstetric care, which tends to be more episodic and limited to pregnant and postpartum women, women receive health care, whether around pregnancy or for nonobstetric issues, in a variety of care settings by members of multiple health disciplines. Having access to standardized clinical data is imperative to providing optimal patient care. The reVITALize Gynecology Data Definitions Initiative leads a national multidisciplinary movement to offer standard gynecologic data definitions for use in written and verbal clinical communication, electronic health record data capture, quality improvement, and clinical research...
March 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28277357/in-pursuit-of-progress-toward-effective-preterm-birth-reduction
#11
James N Martin, Mary DʼAlton, Bo Jacobsson, Jane E Norman
Recently the March of Dimes and the International Federation of Gynecology and Obstetrics Working Group on Preterm Birth released its findings from an extensive cross-country individual patient data analysis of 4.1 million singleton births in five high-income, very high human development index countries. The specific contributions of 21 risk factors for both spontaneous and health care provider-initiated preterm birth were assessed to better understand how these vary among the countries selected for intensive study...
March 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28271654/women-s-health-and-chinese-integrative-medicine
#12
Fan Qu, Fang-Fang Wang, Nicola Robinson, Paul J Hardiman
Researchers in the fields of obstetrics, gynecology, and Chinese integrative medicine (CIM) were invited to share their perspectives on the most recent studies.
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28267442/effects-of-female-genital-mutilation-cutting-on-the-sexual-function-of-sudanese-women-a-cross-sectional-study
#13
Abdulrahim A Rouzi, Rigmor C Berg, Nora Sahly, Susan Alkafy, Faten Alzaban, Hassan Abduljabbar
BACKGROUND: Female Genital Mutilation/Cutting (FGM/C) is a cultural practice that involves several types of removal or other injury to the external female genitalia for non-medical reasons. While much international research has focused on the health consequences of the practice, little is known about sexual functioning among women with various types of FGM/C. OBJECTIVE(S): To assess the impact of FGM/C on the sexual functioning of Sudanese women. STUDY DESIGN: This is a cross-sectional study conducted at Doctor Erfan and Bagedo Hospital, Jeddah, Saudi Arabia...
March 3, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28265843/validity-of-self-reported-fertility-threatening-cancer-treatments-in-female-young-adult-cancer-survivors
#14
Samantha C Roberts, Amber Knight, Brian W Whitcomb, Jessica R Gorman, Andrew C Dietz, H Irene Su
PURPOSE: Detailed cancer treatment information is important to fertility and pregnancy care of female young adult cancer survivors. Accuracy of self-report of treatments that impact fertility and pregnancy is unknown. This study assessed agreement between self-report and medical records on receipt of fertility-threatening treatments. METHODS: A national cohort study of female young adult cancer survivors reported cancer treatments via Web-based questionnaires. Primary cancer treatment records were abstracted...
March 6, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28263049/is-there-a-role-of-single-port-laparoscopy-in-the-treatment-of-endometriosis
#15
Angelos Daniilidis, Kimon Chatzistamatiou, Efstratios Assimakopoulos
BACKGROUND: Endometriosis is among the most common benign gynecological conditions, and it affects 6-15% of women of reproductive. During recent decades, minimally invasive surgical techniques, and especially laparoscopy, have gained significant ground concerning the treatment of gynecological disorders. To date, laparoscopy is considered the gold standard for the diagnosis and treatment of endometriosis. METHODS: Available papers in Pub Med and Scopus data base, written in English language have been used for the current narrative review...
March 6, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28256392/endometrial-cancer-associated-biomarkers-in-bariatric-surgery-candidates-exploration-of-racial-differences
#16
Faina Linkov, Sharon L Goughnour, Robert P Edwards, Anna Lokshin, Ramesh C Ramanathan, Giselle G Hamad, Carol McCloskey, Dana H Bovbjerg
BACKGROUND: Obesity is the main risk factor for endometrial cancer (EC), the most common gynecologic malignancy in the United States. A number of potential risk biomarkers have been associated with EC development, including altered proinflammatory cytokines, chemokines, and adipokines. OBJECTIVES: The overarching aim of this research is to investigate racial differences in the expression of EC-associated biomarkers among bariatric surgery candidates. SETTING: Tertiary academic medical center METHODS: Blood samples were collected from 175 women aged 18 to 72 (mean age: 42...
January 13, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28247032/effect-of-a-patient-tailored-integrative-medicine-program-on-gastro-intestinal-concerns-and-quality-of-life-in-patients-with-breast-and-gynecologic-cancer
#17
Ilanit Shalom-Sharabi, Noah Samuels, Ofer Lavie, Efraim Lev, Lital Keinan-Boker, Elad Schiff, Eran Ben-Arye
CONTEXT AND OBJECTIVES: This study was conducted to assess the impact of a patient-tailored complementary/integrative medicine (CIM) program on gastro-intestinal (GI) symptoms and other concerns in female patients with breast/gynecological cancer undergoing chemotherapy. METHODS: Patients with breast/gynecological cancer reporting GI-related concerns were referred to an integrative physician (IP) consultation. The treatment group included patients agreeing to attend the consultation; controls those who did not...
February 28, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28243415/examining-psychometric-characteristics-of-a-menopausal-health-questionnaire-translation-and-psychometric-evaluation-of-the-persian-version
#18
Nasibeh Sharifi, Somayyeh Khazaeian, Safoura Khazaeian, Marzieh Masjoudi, Azita Fathnejad Kazemi, Anvar-Sadat Nayebi Nia
INTRODUCTION: Menopause is a natural event in a woman's life which affects her general health and quality of life. However, currently there is no Persian instrument for measuring health status during this period. Therefore, the present study was performed to assess the validity and reliability of the Persian version of the Menopausal Health Questionnaire in Iran. METHODS: The questionnaire was translated to Persian with the approach of Jones et al and its validity was assessed by a panel of experts...
January 2017: Electronic Physician
https://www.readbyqxmd.com/read/28242470/lymphedema-after-treatment-for-endometrial-cancer-a-review-of-prevalence-and-risk-factors
#19
REVIEW
Emma Lindqvist, Madelene Wedin, Mats Fredrikson, Preben Kjølhede
Lymphedema is one of the least studied complications of cancer treatment and a chronic condition with a substantial impact on health-related quality of life (HQoL). Lymphedema of the legs (LLL) constitutes a common adverse side effect of lymphadenectomy LA in gynecologic cancer treatment. Primary treatment of endometrial cancer (EC) comprises hysterectomy and bilateral salpingo-oophorectomy. Pelvic and para-aortic lymphadenectomy is recommended in prognostic high risk groups of EC. This review summarizes the published literature concerning the prevalence of LLL after treatment for EC, methods used for measuring LLL, risk factors and HQoL impact...
February 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28238679/how-does-paying-attention-improve-sexual-functioning-in-women-a%C3%A2-review-of-mechanisms
#20
REVIEW
Nikita Arora, Lori A Brotto
INTRODUCTION: Female sexual dysfunction (FSD), consisting of a constellation of distressing sexual symptoms, is highly prevalent worldwide. Given the central role played by psychological factors in the development of FSD, psychologically and in particular mindfulness-based interventions have arisen as potential treatment options for women. Although mindfulness-based interventions have been evaluated in samples of women with gynecologic cancer; a history of sexual abuse; multiple sclerosis; and spinal cord injury; and provoked vestibulodynia, the mechanisms by which mindfulness leads to improvements in sexual functioning are largely unstudied...
February 23, 2017: Sexual Medicine Reviews
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