keyword
https://read.qxmd.com/read/38464765/neuropathological-characteristics-of-abnormal-white-matter-functional-signaling-in-adolescents-with-major-depression
#21
JOURNAL ARTICLE
Xin-Lin Huang, Ju Gao, Yong-Ming Wang, Feng Zhu, Jing Qin, Qian-Nan Yao, Xiao-Bin Zhang, Hong-Yan Sun
BACKGROUND: Major depression disorder (MDD) constitutes a significant mental health concern. Epidemiological surveys indicate that the lifetime prevalence of depression in adolescents is much higher than that in adults, with a corresponding increased risk of suicide. In studying brain dysfunction associated with MDD in adole-scents, research on brain white matter (WM) is sparse. Some researchers even mistakenly regard the signals generated by the WM as noise points. In fact, studies have shown that WM exhibits similar blood oxygen level-dependent signal fluctuations...
February 19, 2024: World Journal of Psychiatry
https://read.qxmd.com/read/38463457/severe-refractory-obsessive-compulsive-disorder-and-depression-should-we-consider-stereotactic-neurosurgery
#22
JOURNAL ARTICLE
Ludvic Zrinzo
Functional neurosurgery involves modulation of activity within neural circuits that drive pathological activity. Neurologists and neurosurgeons have worked closely together, advancing the field for over a century, such that neurosurgical procedures for movement disorders are now accepted as "standard of care", benefiting hundreds of thousands of patients. As with movement disorders, some neuropsychiatric illnesses, including obsessive compulsive disorder and depression, can be framed as disorders of neural networks...
2024: Neuropsychiatric Disease and Treatment
https://read.qxmd.com/read/38462522/mild-encephalopathy-encephalitis-with-reversible-splenial-lesions-after-amphetamine-and-opioid-use
#23
JOURNAL ARTICLE
Youichi Yanagawa, Hiroki Nagasawa, Noriko Torizawa, Ikuto Takeuchi
A 47-year-old woman with a history of substance abuse, depression, and insomnia experienced a collapse. Upon arrival at the hospital, the patient displayed low systolic blood pressure, confusion, dehydration, and renal failure. Urine tests confirmed an amphetamine and opioid overdose. Her condition fluctuated with reduced consciousness, myoclonic movements, fever, and suspected psychogenic seizures. Brain magnetic resonance imaging revealed abnormalities in the splenium of the corpus callosum, which later resolved...
March 11, 2024: Internal Medicine
https://read.qxmd.com/read/38461964/alterations-of-functional-connectivity-dynamics-in-affective-and-psychotic-disorders
#24
JOURNAL ARTICLE
Linnea Hoheisel, Lana Kambeitz-Ilankovic, Julian Wenzel, Shalaila S Haas, Linda A Antonucci, Anne Ruef, Nora Penzel, Frauke Schultze-Lutter, Theresa Lichtenstein, Marlene Rosen, Dominic B Dwyer, Raimo K R Salokangas, Rebekka Lencer, Paolo Brambilla, Stephan Borgwardt, Stephen J Wood, Rachel Upthegrove, Alessandro Bertolino, Stephan Ruhrmann, Eva Meisenzahl, Nikolaos Koutsouleris, Gereon R Fink, Silvia Daun, Joseph Kambeitz
BACKGROUND: Psychosis and depression patients exhibit widespread neurobiological abnormalities. The analysis of dynamic functional connectivity (dFC), allows for the detection of changes in complex brain activity patterns, providing insights into common and unique processes underlying these disorders. METHODS: In the present study, we report the analysis of dFC in a large patient sample including 127 clinical high-risk patients (CHR), 142 recent-onset psychosis (ROP) patients, 134 recent-onset depression (ROD) patients, and 256 healthy controls (HC)...
March 8, 2024: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://read.qxmd.com/read/38461654/hybrid-representation-learning-for-cognitive-diagnosis-in-late-life-depression-over-5-years-with-structural-mri
#25
JOURNAL ARTICLE
Lintao Zhang, Lihong Wang, Minhui Yu, Rong Wu, David C Steffens, Guy G Potter, Mingxia Liu
Late-life depression (LLD) is a highly prevalent mood disorder occurring in older adults and is frequently accompanied by cognitive impairment (CI). Studies have shown that LLD may increase the risk of Alzheimer's disease (AD). However, the heterogeneity of presentation of geriatric depression suggests that multiple biological mechanisms may underlie it. Current biological research on LLD progression incorporates machine learning that combines neuroimaging data with clinical observations. There are few studies on incident cognitive diagnostic outcomes in LLD based on structural MRI (sMRI)...
March 6, 2024: Medical Image Analysis
https://read.qxmd.com/read/38460393/childhood-adversity-modulates-structural-brain-changes-in-borderline-personality-but-not-in-major-depression-disorder
#26
JOURNAL ARTICLE
Vicente Camacho-Téllez, Mariana N Castro, Agustina E Wainsztein, Ximena Goldberg, Gabriela De Pino, Elsa Y Costanzo, Narcís Cardoner, José M Menchón, Carles Soriano-Mas, Salvador M Guinjoan, Mirta F Villarreal
Adverse childhood experiences (ACEs) negatively affect the function and structure of emotion brain circuits, increasing the risk of various psychiatric disorders. It is unclear if ACEs show disorder specificity with respect to their effects on brain structure. We aimed to investigate whether the structural brain effects of ACEs differ between patients with major depression (MDD) and borderline personality disorder (BPD). These disorders share many symptoms but likely have different etiologies. To achieve our goal, we obtained structural 3T-MRI images from 20 healthy controls (HC), 19 MDD patients, and 18 BPD patients, and measured cortical thickness and subcortical gray matter volumes...
March 1, 2024: Psychiatry Research. Neuroimaging
https://read.qxmd.com/read/38453029/effective-connectivity-of-the-locus-coeruleus-in-patients-with-late-life-major-depressive-disorder-or-mild-cognitive-impairment
#27
JOURNAL ARTICLE
Pablo Maturana-Quijada, Pamela Chavarría-Elizondo, Inés Del Cerro, Ignacio Martínez-Zalacaín, Asier Juaneda-Seguí, Andrés Guinea-Izquierdo, Jordi Gascón-Bayarri, Ramón Reñé, Mikel Urretavizcaya, José M Menchón, Isidre Ferrer, Virginia Soria, Carles Soriano-Mas
INTRODUCTION: We compared effective connectivity from the locus coeruleus (LC) during the resting-state in patients with late-life Major Depressive Disorder (MDD), individuals with amnestic Mild Cognitive Impairment (aMCI), and Healthy Controls (HCs). PARTICIPANTS: 23 patients with late-life MDD, 22 patients with aMCI, and 28 HCs. MATERIAL AND METHODS: Participants were assessed in two time-points, 2 years apart. They underwent a resting-state functional magnetic resonance imaging and a high-resolution anatomical acquisition, as well as clinical assessments...
March 5, 2024: Span J Psychiatry Ment Health
https://read.qxmd.com/read/38451374/evaluation-of-the-effect-of-cervical-and-lumbar-disc-herniations-on-female-sexual-function-a-comparative-prospective-study
#28
JOURNAL ARTICLE
Sameh Fayek GamalEl Din, Nashaat Nabil, Mohamed Alaa, Mohamed Ahmed Abdel Salam, Ahmed Raef, Rana Barakat Elhalaly, Ahmed Abo Sief
PURPOSE: We aimed to evaluate the effect of cervical disc herniation (CDH) and lumbar disc herniation (LDH) on female sexual functioning before and after surgical intervention. METHODS: The current study was conducted from February 2022 to February 2023. A total of 100 sexually active female patients in their reproductive phase who were diagnosed with CDH and LDH based on physical examination and previous magnetic resonance imaging (MRI) results, as well as 50 healthy females, were enrolled...
March 7, 2024: European Spine Journal
https://read.qxmd.com/read/38450380/revised-temperament-and-character-inventory-factors-predict-neuropsychiatric-symptoms-and-aging-related-cognitive-decline-across-25%C3%A2-years
#29
JOURNAL ARTICLE
Lucas Ronat, Michael Rönnlund, Rolf Adolfsson, Alexandru Hanganu, Sara Pudas
INTRODUCTION: Personality traits and neuropsychiatric symptoms such as neuroticism and depression share genetic overlap and have both been identified as risks factors for development of aging-related neurocognitive decline and Alzheimer's disease (AD). This study aimed to examine revised personality factors derived from the Temperament and Character Inventory, previously shown to be associated with psychiatric disorders, as predictors of neuropsychiatric, cognitive, and brain trajectories of participants from a population-based aging study...
2024: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/38447356/neural-correlates-of-cognitive-behavioral-therapy-based-interventions-for-bipolar-disorder-a-scoping-review
#30
REVIEW
Francesca Girelli, Maria Gloria Rossetti, Cinzia Perlini, Marcella Bellani
Cognitive Behavioral Therapy (CBT) is among the gold-standard psychotherapeutic interventions for the treatment of psychiatric disorders, including bipolar disorder (BD). While the clinical response of CBT in patients with BD has been widely investigated, its neural correlates remain poorly explored. Therefore, this scoping review aimed to discuss neuroimaging studies on CBT-based interventions in bipolar populations. Particular attention has been paid to similarities and differences between studies to inform future research...
February 26, 2024: Journal of Psychiatric Research
https://read.qxmd.com/read/38447315/classification-of-recurrent-major-depressive-disorder-using-a-residual-denoising-autoencoder-framework-insights-from-large-scale-multisite-fmri-data
#31
JOURNAL ARTICLE
Peishan Dai, Yun Shi, Da Lu, Ying Zhou, Jialin Luo, Zhuang He, Zailiang Chen, Beiji Zou, Hui Tang, Zhongchao Huang, Shenghui Liao
BACKGROUND AND OBJECTIVE: Recurrent major depressive disorder (rMDD) has a high recurrence rate, and symptoms often worsen with each episode. Classifying rMDD using functional magnetic resonance imaging (fMRI) can enhance understanding of brain activity and aid diagnosis and treatment of this disorder. METHODS: We developed a Residual Denoising Autoencoder (Res-DAE) framework for the classification of rMDD. The functional connectivity (FC) was extracted from fMRI data as features...
March 2, 2024: Computer Methods and Programs in Biomedicine
https://read.qxmd.com/read/38444878/the-emotion-regulation-of-acupuncture-in-chronic-low-back-pain-a-clinical-neuroimaging-protocol
#32
JOURNAL ARTICLE
Peng Lai, Shirui Cheng, Xingyao Chen, Fangdong Cheng, Jun Cheng, Ming Xin, Deliang Zhu, Zhengjie Li, Xi Wu, Fang Zeng
INTRODUCTION: Acupuncture is effective for patients with chronic low back pain (CLBP), which can relieve pain intensity and regulate negative emotional states such as pain-related anxiety and depression. Previous studies mainly discuss the analgesic mechanism of acupuncture treatment of CLBP, but there are multiple dimensions to pain, including sensation, emotion and cognition. Therefore, this study aims to investigate the central mechanism of acupuncture for CLBP from the perspective of emotional regulation by functional magnetic resonance imaging (fMRI)...
2024: Journal of Pain Research
https://read.qxmd.com/read/38444775/structural-and-functional-abnormalities-in-the-medial-prefrontal-cortex-were-associated-with-pain-and-depressive-symptoms-in-patients-with-adhesive-capsulitis
#33
JOURNAL ARTICLE
Jie Li, Rui Zhao, Chenguang Wang, Jiajun Song, Xing Guo, Yeqi Ge, Xu Chu
INTRODUCTION: Chronic pain and depression have been shown to coexist in patients with adhesive capsulitis (AC). Recent studies identified the shared brain plasticity between pain and depression; however, how such neuroplasticity contributes to AC remains unclear. Here, we employed a combination of psychophysics, structural MRI, and functional MRI techniques to examine the brain's structural and functional changes in AC. METHODS: Fifty-two patients with AC and 52 healthy controls (HCs) were included in our study...
April 2024: Pain Reports
https://read.qxmd.com/read/38443878/reduced-gray-matter-volume-of-the-hippocampal-tail-in-melancholic-depression-evidence-from-an-mri-study
#34
JOURNAL ARTICLE
Zhaosong Chu, Lijin Yuan, Kun Lian, Mengxin He, Yi Lu, Yuqi Cheng, Xiufeng Xu, Zonglin Shen
BACKGROUND: Melancholic depression (MD) is one of the most prevalent and severe subtypes of major depressive disorder (MDD). Previous studies have revealed inconsistent results regarding alterations in grey matter volume (GMV) of the hippocampus and amygdala of MD patients, possibly due to overlooking the complexity of their internal structure. The hippocampus and amygdala consist of multiple and functionally distinct subregions, and these subregions may play different roles in MD. This study aims to investigate the volumetric alterations of each subregion of the hippocampus and amygdala in patients with MD and non-melancholic depression (NMD)...
March 5, 2024: BMC Psychiatry
https://read.qxmd.com/read/38443354/a-distinctive-subcortical-functional-connectivity-pattern-linking-negative-affect-and-treatment-outcome-in-major-depressive-disorder
#35
JOURNAL ARTICLE
Yan-Kun Wu, Yun-Ai Su, Lin-Lin Zhu, ChaoGan Yan, Ji-Tao Li, Jing-Yu Lin, JingXu Chen, Lin Chen, Ke Li, Dan J Stein, Tian-Mei Si
Major depressive disorder (MDD) is associated with functional disturbances in subcortical regions. In this naturalistic prospective study (NCT03294525), we aimed to investigate relationships among subcortical functional connectivity (FC), mood symptom profiles and treatment outcome in MDD using multivariate methods. Medication-free participants with MDD (n = 135) underwent a functional magnetic resonance imaging scan at baseline and completed posttreatment clinical assessment after 8 weeks of antidepressant monotherapy...
March 5, 2024: Translational Psychiatry
https://read.qxmd.com/read/38438854/expanded-clinical-phenotype-and-untargeted-metabolomics-analysis-in-rars2-related-mitochondrial-disorder-a-case-report
#36
JOURNAL ARTICLE
Ameya S Walimbe, Keren Machol, Stephen F Kralik, Elizabeth A Mizerik, Yoel Gofin, Mir Reza Bekheirnia, Charul Gijavanekar, Sarah H Elsea, Lisa T Emrick, Fernando Scaglia
BACKGROUND: RARS2-related mitochondrial disorder is an autosomal recessive mitochondrial encephalopathy caused by biallelic pathogenic variants in the gene encoding the mitochondrial arginyl-transfer RNA synthetase 2 (RARS2, MIM *611524, NM_020320.5). RARS2 catalyzes the transfer of L-arginine to its cognate tRNA during the translation of mitochondrially-encoded proteins. The classical presentation of RARS2-related mitochondrial disorder includes pontocerebellar hypoplasia (PCH), progressive microcephaly, profound developmental delay, feeding difficulties, and hypotonia...
March 4, 2024: BMC Neurology
https://read.qxmd.com/read/38433711/retinal-vascular-density-as-a-potential-biomarker-of-diabetic-cerebral-small-vessel-disease
#37
JOURNAL ARTICLE
Yinqiong Huang, Siyun Wang, Chi Cai, Xinwei Huang, Yan Chen, Xiaohong Wu, Yiping Zhang, Yan Zhang, Xiahong Lin
AIM: The retina and brain share similar anatomical and physiological features. Thus, retinal imaging by optical coherence tomography angiography (OCTA) might be a potential tool for the early diagnosis of diabetic cerebral small vessel disease (CSVD). In this study, we aimed to evaluate retinal vascular density (VD) in diabetic CSVD by OCTA imaging and explore the associations between retinal VD and cerebral magnetic resonance imaging (MRI) markers and cognitive function. METHODS: In total, 131 patients were enrolled, including CSVD (n = 43) and non-CSVD groups (n = 88)...
March 4, 2024: Diabetes, Obesity & Metabolism
https://read.qxmd.com/read/38431655/exploring-the-impact-of-immersive-virtual-reality-on-depression-knowledge-and-stigma-reduction-a-cross-over-rct-fmri-study
#38
JOURNAL ARTICLE
Wey Guan Lem, Kelssy Hitomi Dos Santos Kawata, Hiroshi Oyama
The stigma of mental illness is a form of negative judgmental knowledge and is a barrier to individual seeking treatment. Contact-based educational interventions with first-person perspective (1PP) combined with immersive virtual reality (IVR) is promising as an anti-stigma intervention. This study aims to investigate the effectiveness of 1PP anti-stigma IVR intervention compared to video in enhancing depression knowledge and reducing stigma, as well as to examine the corresponding depression knowledge brain activity change using functional magnetic resonance imaging (fMRI)...
March 2, 2024: Scientific Reports
https://read.qxmd.com/read/38430994/evaluation-of-fluoroscopically-guided-transforaminal-selective-nerve-root-sleeve-injections-for-lumbar-spinal-stenosis-with-radiculopathy-utilizing-patient-reported-outcome-measurement-information-system-as-an-outcome-measure
#39
JOURNAL ARTICLE
Andrew R Stephens, Ramz El Hassasn, Rajeev K Patel
OBJECTIVE: To evaluate the therapeutic effect of transforaminal selective nerve root sleeve injections (TFSNRIs) in a specific subset of patients with clinical symptoms and presentation consistent with spinal stenosis DESIGN: Retrospective review SETTING: tertiary academic spine center. PARTICIPANTS: A total of 176 patients with radicular leg pain with or without low back pain as well as ≥3 clinical features of spinal stenosis and corroborative radiographic features of spinal stenosis on lumbar spine magnetic resonance imaging without confounding spinal pathology...
February 29, 2024: Archives of Physical Medicine and Rehabilitation
https://read.qxmd.com/read/38430816/explainable-multimodal-prediction-of-treatment-resistance-in-patients-with-depression-leveraging-brain-morphometry-and-natural-language-processing
#40
JOURNAL ARTICLE
Dong Yun Lee, Narae Kim, ChulHyoung Park, Sujin Gan, Sang Joon Son, Rae Woong Park, Bumhee Park
Although 20 % of patients with depression receiving treatment do not achieve remission, predicting treatment-resistant depression (TRD) remains challenging. In this study, we aimed to develop an explainable multimodal prediction model for TRD using structured electronic medical record data, brain morphometry, and natural language processing. In total, 247 patients with a new depressive episode were included. TRD-predictive models were developed based on the combination of following parameters: selected tabular dataset features, independent components-map weightings from brain T1-weighted magnetic resonance imaging (MRI), and topic probabilities from clinical notes...
February 25, 2024: Psychiatry Research
keyword
keyword
109117
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.