Linnea Hoheisel, Lana Kambeitz-Ilankovic, Julian Wenzel, Shalaila S Haas, Linda A Antonucci, Anne Ruef, Nora Penzel, Frauke Schultze-Lutter, Theresa Lichtenstein, Marlene Rosen, Dominic B Dwyer, Raimo K R Salokangas, Rebekka Lencer, Paolo Brambilla, Stephan Borgwardt, Stephen J Wood, Rachel Upthegrove, Alessandro Bertolino, Stephan Ruhrmann, Eva Meisenzahl, Nikolaos Koutsouleris, Gereon R Fink, Silvia Daun, Joseph Kambeitz
BACKGROUND: Psychosis and depression patients exhibit widespread neurobiological abnormalities. The analysis of dynamic functional connectivity (dFC), allows for the detection of changes in complex brain activity patterns, providing insights into common and unique processes underlying these disorders. METHODS: In the present study, we report the analysis of dFC in a large patient sample including 127 clinical high-risk patients (CHR), 142 recent-onset psychosis (ROP) patients, 134 recent-onset depression (ROD) patients, and 256 healthy controls (HC)...
March 8, 2024: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging