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https://www.readbyqxmd.com/read/28727718/quantity-of-disc-removal-and-radiological-outcomes-of-percutaneous-endoscopic-lumbar-discectomy
#1
Ji Han Heo, Chi Heon Kim, Chun Kee Chung, Yunhee Choi, Young-Geun Seo, Dong Hoi Kim, Sung Bae Park, Jung Hyeon Moon, Won Heo, Jong-Myung Jung
BACKGROUND: Herniated intervertebral disc disease (HIVD) is a common cause of lower back and leg pain. Percutaneous endoscopic lumbar discectomy (PELD) is indicated when non-surgical treatments such as medication and interventions are intractable. Ruptured discs and loose fragments inside discs are removed during PELD. Nerve root decompression is usually assessed by visualizing the free movement of the traversing nerve root or epidural fat, the free passage of a probe into the epidural space, the depression of the annulus, and the removal of the expected ruptured discs and loose fragments based on preoperative magnetic resonance images (MRI)...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28715552/large-perivascular-spaces-visible-on-magnetic-resonance-imaging-cerebral-small-vessel-disease-progression-and-risk-of-dementia-the-age-gene-environment-susceptibility-reykjavik-study
#2
Jie Ding, Sigurður Sigurðsson, Pálmi V Jónsson, Gudny Eiriksdottir, Andreas Charidimou, Oscar L Lopez, Mark A van Buchem, Vilmundur Guðnason, Lenore J Launer
Importance: With advancing age, an increased visibility of perivascular spaces (PVSs) on magnetic resonance imaging (MRI) is hypothesized to represent impaired drainage of interstitial fluid from the brain and may reflect underlying cerebral small vessel disease (SVD). However, whether large perivascular spaces (L-PVSs) (>3 mm in diameter) visible on MRI are associated with SVD and cognitive deterioration in older individuals is unknown. Objective: To examine whether L-PVSs are associated with the progression of the established MRI markers of SVD, cognitive decline, and increased risk of dementia...
July 17, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28704802/trajectories-of-depressive-symptoms-and-their-relationship-to-the-progression-of-dementia
#3
Maria Lage Barca, Karin Persson, Rannveig Eldholm, Jūratė Šaltytė Benth, Hege Kersten, Anne-Brita Knapskog, Ingvild Saltvedt, Geir Selbaek, Knut Engedal
BACKGROUND: The relationship between progression of Alzheimer's disease and depression and its underlying mechanisms has scarcely been studied. METHODS: A sample of 282 outpatients with Alzheimer's disease (AD; 105 with amnestic AD and 177 with Alzheimer's dementia) from Norway were followed up for an average of two years. Assessment included Cornell Scale for Depression in Dementia and Clinical Dementia Rating Scale (CDR) at baseline and follow-up to examine the relationship between AD and depression...
July 8, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28700672/prediction-of-clinical-depression-scores-and-detection-of-changes-in-whole-brain-using-resting-state-functional-mri-data-with-partial-least-squares-regression
#4
Kosuke Yoshida, Yu Shimizu, Junichiro Yoshimoto, Masahiro Takamura, Go Okada, Yasumasa Okamoto, Shigeto Yamawaki, Kenji Doya
In diagnostic applications of statistical machine learning methods to brain imaging data, common problems include data high-dimensionality and co-linearity, which often cause over-fitting and instability. To overcome these problems, we applied partial least squares (PLS) regression to resting-state functional magnetic resonance imaging (rs-fMRI) data, creating a low-dimensional representation that relates symptoms to brain activity and that predicts clinical measures. Our experimental results, based upon data from clinically depressed patients and healthy controls, demonstrated that PLS and its kernel variants provided significantly better prediction of clinical measures than ordinary linear regression...
2017: PloS One
https://www.readbyqxmd.com/read/28694044/more-randomized-and-resilient-in-the-topological-properties-of-functional-brain-networks-in-patients-with-major-depressive-disorder
#5
Huaizhou Li, Haiyan Zhou, Yang Yang, Haiyuan Wang, Ning Zhong
Previous studies have reported the enhanced randomization of functional brain networks in patients with major depressive disorder (MDD). However, little is known about the changes of key nodal attributes for randomization, the resilience of network, and the clinical significance of the alterations. In this study, we collected the resting-state functional MRI data from 19 MDD patients and 19 healthy control (HC) individuals. Graph theory analysis showed that decreases were found in the small-worldness, clustering coefficient, local efficiency, and characteristic path length (i...
July 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28691530/depressive-symptoms-in-parkinson-s-disease-are-related-to-decreased-left-hippocampal-volume-correlation-with-the-15-item-shortened-version-of-the-geriatric-depression-scale
#6
Masami Goto, Koji Kamagata, Taku Hatano, Nobutaka Hattori, Osamu Abe, Shigeki Aoki, Masaaki Hori, Tsutomu Gomi
Background The relationship between hippocampal and amygdaloid volumes and depression in patients with Parkinson's disease (PD) is a controversial issue. Purpose To investigate the correlation between the 15-item shortened version of the Geriatric Depression Scale (GDS-15) and gray matter volume in PD. Material and Methods In the present study, 46 participants with PD were scanned with 3 T magnetic resonance imaging (MRI) to obtain three-dimensional (3D) T1-weighted (T1W) images. Neurologists specializing in movement disorders performed clinical evaluations of the participants (e...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28690225/-grey-matter-concentration-revealed-by-voxel-based-morphometry-in-individuals-with-cognitive-vulnerability-to-depression
#7
Shuwen Yuan, Hui Lei, Shuqiao Yao, Xiaocui Zhang
To explore the grey matter concentration in individuals with cognitive vulnerability to depression.
 Methods: Thirty individuals with cognitive vulnerability to depression and thirty age- and gender-matched healthy controls were enrolled in this study, and they were subjected to magnetic resonance imaging (MRI) examination. The grey matter concentration differences were compared between the two groups by using voxel-based morphometry (VBM) following MRI.
 Results: Individuals with cognitive vulnerability to depression showed significantly lower grey matter density in bilateral insular, left cerebellum, right supplementary motor area, and left precentral gyrus than those in the healthy controls, while the healthy controls showed significantly lower grey density in the right inferior frontal gyrus, right middle frontal gyrus, and left cuneus than those in the individuals with cognitive vulnerability to depression...
June 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28688824/white-matter-lesions-are-associated-with-specific-depressive-symptom-trajectories-among-incident-depression-and-dementia-populations-three-city-dijon-mri-study
#8
Phillip J Tully, Stephanie Debette, Bernard Mazoyer, Christophe Tzourio
OBJECTIVE: Evidence is mixed as to whether periventricular or deep white matter hyperintensities (WMHs) increase the risk for depressive symptoms, partly because of heterogeneity in depression measurement, short follow-up, and confounding by prodromal dementia. The study objective was to evaluate WMH volume in relation to discrete depressive symptoms over 10 years, stratifying by incident depression and dementia. METHODS: In this prospective longitudinal cohort study of a representative population sample from Dijon, France, 1,440 participants aged 65-80 years (median age: 72 years; 59...
July 5, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28681749/bilateral-anterior-capsulotomy-for-patients-with-refractory-obsessive-compulsive-disorder-a-multicenter-long-term-follow-up-study
#9
Hong Bin Liu, Qi Zhong, Wei Wang
OBJECTIVE: The objectives of this retrospective study were to analyze the short-term and long-term effects and complications of stereotactic anterior capsulotomy for patients with refractory obsessive-compulsive disorder (OCD). The advantages and disadvantages of stereotactic anterior capsulotomy have been discussed. MATERIALS AND METHODS: Between October 2007 and June 2010, 37 patients with OCD underwent anterior capsulotomy in West China Hospital of Sichuan University or Mian Yang Central Hospital...
July 2017: Neurology India
https://www.readbyqxmd.com/read/28674759/impaired-sensory-processing-measured-by-functional-mri-in-bipolar-disorder-manic-and-depressed-mood-states
#10
Joseph J Shaffer, Casey P Johnson, Jess G Fiedorowicz, Gary E Christensen, John A Wemmie, Vincent A Magnotta
Bipolar disorder is characterized by recurring episodes of depression and mania. Defining differences in brain function during these states is an important goal of bipolar disorder research. However, few imaging studies have directly compared brain activity between bipolar mood states. Herein, we compare functional magnetic resonance imaging (fMRI) responses during a flashing checkerboard stimulus between bipolar participants across mood states (euthymia, depression, and mania) in order to identify functional differences between these states...
July 3, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28672181/corpus-callosum-macro-and-microstructure-in-late-life-depression
#11
Louise Emsell, Christopher Adamson, François-Laurent De Winter, Thibo Billiet, Daan Christiaens, Filip Bouckaert, Katarzyna Adamczuk, Rik Vandenberghe, Marc L Seal, Pascal Sienaert, Stefan Sunaert, Mathieu Vandenbulcke
BACKGROUND: Differences in corpus callosum (CC) morphology and microstructure have been implicated in late-life depression and may distinguish between late and early-onset forms of the illness. However, a multimodal approach using complementary imaging techniques is required to disentangle microstructural alterations from macrostructural partial volume effects. METHODS: 107 older adults were assessed: 55 currently-depressed patients without dementia and 52 controls without cognitive impairment...
June 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28671125/distribution-of-types-of-dementia-in-the-first-100-patients-seen-at-a-dementia-clinic-in-india
#12
Vijay Chandra, Veer Singh Mehta
The aim of our study was to determine if the distribution of types of dementia could explain the reported lower prevalence of dementia in India. The study is an observational study of the first 100 cases of dementia. All patients were evaluated clinically and with blood tests and MRI of the brain. The causes of dementia were: Lewy body dementia (22%), depression (20%), Alzheimer's disease (13%), and mild cognitive impairment (18%). Other dementias were less common. The distribution of dementia types in this series is different from that reported globally...
June 28, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28670128/clinical-features-of-limbic-encephalitis-with-lgi1-antibody
#13
Meiling Wang, Xiaoyu Cao, Qingxin Liu, Wenbin Ma, Xiaoqian Guo, Xuewu Liu
OBJECTIVE: The objective of this study was to analyze the clinical manifestation, course, evolution, image manifestation, and treatments of LGI1 limbic encephalitis (LE). PATIENTS AND METHODS: Studies confirmed that LE with the complex antibody of voltage-gated potassium channels is LGI1 LE. Since then, LE cases have been reported. In this study, 10 typical LE cases were searched in PubMed. These cases and one additional case, which we reported herein, were retrospectively analyzed...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28667426/maternal-depressive-symptoms-during-pregnancy-are-associated-with-amygdala-hyperresponsivity-in-children
#14
Noortje J F van der Knaap, Floris Klumpers, Hanan El Marroun, Sabine Mous, Dirk Schubert, Vincent Jaddoe, Albert Hofman, Judith R Homberg, Henning Tiemeier, Tonya White, Guillén Fernández
Depression during pregnancy is highly prevalent and has a multitude of potential risks of the offspring. Among confirmed consequences is a higher risk of psychopathology. However, it is unknown how maternal depression may impact the child's brain to mediate this vulnerability. Here we studied amygdala functioning, using task-based functional MRI, in children aged 6-9 years as a function of prenatal maternal depressive symptoms selected from a prospective population-based sample (The Generation R Study). We show that children exposed to clinically relevant maternal depressive symptoms during pregnancy (N = 19) have increased amygdala responses to negative emotional faces compared to control children (N = 20) [F(1,36) 7...
June 30, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28666514/a-rare-neuropsychiatric-presentation-of-adult-onset-wilson-s-disease
#15
Ather Muneer
Wilson's disease is characterised by deposition of copper in various tissues of the body, most markedly in the liver and the brain. Cerebral involvement, evident as neuropsychiatric symptoms, may be the presenting form of the illness in up to 50% of the adults. When patients present initially with psychiatric manifestations, the correct diagnosis is frequently missed. This case report describes an adult in his late 20's who presented with symptoms of major depressive disorder, but failed to respond to standard antidepressant treatment...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28665375/-the-comprehensive-step-by-step-rehabilitation-of-the-patients-after-acute-disturbances-of-the-cerebral-circulation
#16
N F Miryutova, V A Chistyakova, V A Vorob'eva, A A Zaitsev
AIM: The objective of the present study was to evaluate the therapeutic effectiveness of the comprehensive one- and two-stage rehabilitation including the application of mirror therapy and orthetics on an individual basis. MATERIAL AND METHODS: The study included 125 patients (66 men and 59 women) at the medium age of 57 (52; 63) years who had undergone the acute disorders of cerebral circulation (the diagnosis was verified based on the results of CT or MRI of the brain)...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/28661067/medial-prefrontal-cortex-deficits-correlate-with-unrefreshing-sleep-in-patients-with-chronic-fatigue-syndrome
#17
Zack Y Shan, Richard Kwiatek, Richard Burnet, Peter Del Fante, Donald R Staines, Sonya M Marshall-Gradisnik, Leighton R Barnden
Unrefreshing sleep is a hallmark of chronic fatigue syndrome/myalgic encephalomyelitis (CFS). This study examined brain structure variations associated with sleep quality in patients with CFS. 38 patients with CFS (34.8 ± 10.1 years old) and 14 normal controls (NCs) (34.7 ± 8.4 years old) were recruited. All subjects completed the Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index (PSQI), and Chalder Fatigue Scale (CFQ) questionnaires. Brain MRI measures included global and regional grey and white matter volumes, magnetization transfer T1 weighted (MT-T1w) intensities, and T1 weighted (T1w) and T2 weighted spin echo signal intensities...
June 29, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28657552/the-neural-correlates-of-the-metacognitive-function-of-other-perspective-a-multiple-regression-analysis-study
#18
Syouichi Shiota, Yasumasa Okamoto, Go Okada, Koki Takagaki, Masahiro Takamura, Asako Mori, Satoshi Yokoyama, Yoshiko Nishiyama, Ran Jinnin, Ryuichiro Hashimoto, Shigeto Yamawaki
Perspective taking is defined as the social cognitive function of imagining the world or imagining oneself from another's viewpoint. Previously, we reported that behavioral activation increased the dorsal medial prefrontal cortex (dmPFC) activation during other perspective self-referential processing for positive words in subthreshold depression, but did not report whether metacognitive function was related to the dmPFC activation. Therefore, we sought to test the relationship between the dmPFC activation during other perspective self-referential processing for positive words and an individual's metacognitive evaluation of other perspective...
August 2, 2017: Neuroreport
https://www.readbyqxmd.com/read/28653033/neuroticism-depression-and-anxiety-traits-exacerbate-the-state-of-cognitive-impairment-and-hippocampal-vulnerability-to-alzheimer-s-disease
#19
Valérie Zufferey, Alessia Donati, Julius Popp, Reto Meuli, Jérôme Rossier, Richard Frackowiak, Bogdan Draganski, Armin von Gunten, Ferath Kherif
INTRODUCTION: Certain personality traits are associated with higher risk of Alzheimer's disease, similar to cognitive impairment. The identification of biological markers associated with personality in mild cognitive impairment could advance the early detection of Alzheimer's disease. METHODS: We used hierarchical multivariate linear models to quantify the interaction between personality traits, state of cognitive impairment, and MRI biomarkers (gray matter brain volume, gray matter mean water diffusion) in the medial temporal lobe (MTL)...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/28652971/loss-of-integrity-and-atrophy-in-cingulate-structural-covariance-networks-in-parkinson-s-disease
#20
Laura J de Schipper, Jeroen van der Grond, Johan Marinus, Johanna M L Henselmans, Jacobus J van Hilten
BACKGROUND: In Parkinson's disease (PD), the relation between cortical brain atrophy on MRI and clinical progression is not straightforward. Determination of changes in structural covariance networks - patterns of covariance in grey matter density - has shown to be a valuable technique to detect subtle grey matter variations. We evaluated how structural network integrity in PD is related to clinical data. METHODS: 3 Tesla MRI was performed in 159 PD patients. We used nine standardized structural covariance networks identified in 370 healthy subjects as a template in the analysis of the PD data...
2017: NeuroImage: Clinical
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