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https://www.readbyqxmd.com/read/30010694/cost-effectiveness-of-renal-denervation-therapy-for-treatment-resistant-hypertension-a-best-case-scenario
#1
Enayet K Chowdhury, Christopher M Reid, Ella Zomer, Darren J Kelly, Danny Liew
Background: Renal denervation (RDN) is effective at reducing blood pressure (BP) among patients with treatment-resistant hypertension (TRH). However, recent findings regarding the effectiveness of RDN for BP reduction compared to standard treatment of care (SoC) has initiated rigorous debate about its role in TRH management. In this study, we sought to determine the thresholds for cardiovascular risk and costs of RDN which would make RDN cost-effective. Methods: A Markov model was constructed to simulate cardiovascular events over a life time among TRH subjects aged 60-years at baseline, and without prior cardiovascular disease...
July 13, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/30010598/real-time-event-driven-classification-technique-for-early-detection-and-prevention-of-myocardial-infarction-on-wearable-systems
#2
Dionisije Sopic, Amin Aminifar, Amir Aminifar, David Atienza
A considerable portion of government health-care spending is allocated to the continuous monitoring of patients suffering from cardiovascular diseases, particularly myocardial infarction (MI). Wearable devices present a cost-effective means of monitoring patients' vital signs in ambulatory settings. A major challenge is to design such ultra-low energy devices for long-term patient monitoring. In this paper, we present a real-time event-driven classification technique based on the random forest classification scheme, which uses a confidence-related decision-making process...
July 16, 2018: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/30010594/blood-cholesterol-monitoring-with-smartphone-as-miniaturized-electrochemical-analyzer-for-cardiovascular-disease-prevention
#3
Yusheng Fu, Jinhong Guo
Currently, cardiovascular diseases become one of the major threat to human's life. The early prevention of cardiovascular diseases plays a critical role in the healthcare engineering. Point of care monitoring the blood lipid level is capable of making the positive contribution to the prevention of cardiovascular disease. Ubiquitous smartphones paved the way as the flexible and widespread platform for the interaction of various health information. In this manuscript, we report the world's first medical smartphone as an electrochemical analyzer for blood lipid monitoring...
July 16, 2018: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/30008800/prevalence-of-non-communicable-diseases-and-access-to-care-among-non-camp-syrian-refugees-in-northern-jordan
#4
Manuela Rehr, Muhammad Shoaib, Sara Ellithy, Suhib Okour, Cono Ariti, Idriss Ait-Bouziad, Paul van den Bosch, Anais Deprade, Mohammad Altarawneh, Abdel Shafei, Sadeq Gabashneh, Annick Lenglet
Background: Tackling the high non-communicable disease (NCD) burden among Syrian refugees poses a challenge to humanitarian actors and host countries. Current response priorities are the identification and integration of key interventions for NCD care into humanitarian programs as well as sustainable financing. To provide evidence for effective NCD intervention planning, we conducted a cross-sectional survey among non-camp Syrian refugees in northern Jordan to investigate the burden and determinants for high NCDs prevalence and NCD multi-morbidities and assess the access to NCD care...
2018: Conflict and Health
https://www.readbyqxmd.com/read/30005962/surveillance-of-pediatric-hypertension-using-smartphone-technology
#5
Hope Bussenius, Angela M Zeck, Bryan Williams, Angela Haynes-Ferere
INTRODUCTION: Elevated blood pressure is becoming increasingly common in the pediatric population. Hypertension costs nearly $51 billion/year, and cardiovascular disease is responsible for 17% of the nation's health care expenditures. Traditionally, time-consuming and complicated interpretation standards result in infrequent pediatric blood pressure screenings. This may lead to the under-diagnosis of pediatric hypertension. Early detection of elevated blood pressure is important in order to prevent hypertension related conditions such as, target organ damage, left ventricular hypertrophy, and cerebrovascular disease...
July 10, 2018: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/30005935/second-generation-lai-are-associated-to-favorable-outcome-in-a-cohort-of-incident-patients-diagnosed-with-schizophrenia
#6
René Ernst Nielsen, Kristian Bjørn Hessellund, Jan Brink Valentin, Rasmus W Licht
OBJECTIVE: Investigate the associations of long-acting injectable (LAI) second generation antipsychotic drugs with number of relapses, psychiatric admissions, days hospitalized, intentional self-harm events, and costs linked to hospitalizations in incident patients diagnosed with schizophrenia. METHOD: A nationwide, population-based, retrospective study utilizing mirror-image models before and after initiation of LAI SGA. RESULTS: 10,509 patients were included as study population, with analyses being conducted on 2223 patients in a six-month period, 1383 in a 12-month period, 713 in a 24-month period...
July 10, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/30005761/economic-burden-of-cardiovascular-disease-in-type-2-diabetes-a-systematic-review
#7
REVIEW
Thomas R Einarson, Annabel Acs, Craig Ludwig, Ulrik H Panton
BACKGROUND: Cardiovascular diseases (CVDs) constitute major comorbidities in type 2 diabetes mellitus (T2DM), contributing substantially to treatment costs for T2DM. An updated overview of the economic burden of CVD in T2DM has not been presented to date. OBJECTIVE: To systematically review published articles describing the costs associated with treating CVD in people with T2DM. METHODS: Two reviewers searched MEDLINE, Embase, and abstracts from scientific meetings to identify original research published between 2007 and 2017, with no restrictions on language...
July 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/30004797/pharmacological-management-of-hypertension-in-the-elderly-and-frail-populations
#8
Ashish Correa, Yogita Rochlani, Mohammed Hassan Khan, Wilbert S Aronow
Cardiovascular disease is a leading cause of mortality in the elderly. Hypertension is an important modifiable risk factor that contributes to cardiovascular morbidity and mortality. The prevalence of hypertension is known to increase with age, and hypertension has been associated with an increase in risk for cardiovascular disease in the elderly. There is a wealth of evidence that supports aggressive control of blood pressure to lower cardiovascular risk in the general population. However, there are limited data to guide management of hypertension in the elderly and frail patient subgroups...
July 13, 2018: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/30002725/mobile-personal-health-monitoring-for-automated-classification-of-electrocardiogram-signals-in-elderly
#9
Luis J Mena, Vanessa G Félix, Alberto Ochoa, Rodolfo Ostos, Eduardo González, Javier Aspuru, Pablo Velarde, Gladys E Maestre
Mobile electrocardiogram (ECG) monitoring is an emerging area that has received increasing attention in recent years, but still real-life validation for elderly residing in low and middle-income countries is scarce. We developed a wearable ECG monitor that is integrated with a self-designed wireless sensor for ECG signal acquisition. It is used with a native purposely designed smartphone application, based on machine learning techniques, for automated classification of captured ECG beats from aged people. When tested on 100 older adults, the monitoring system discriminated normal and abnormal ECG signals with a high degree of accuracy (97%), sensitivity (100%), and specificity (96...
2018: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29998344/screening-for-peripheral-artery-disease-and-cardiovascular-disease-risk-assessment-with-the-ankle-brachial-index-us-preventive-services-task-force-recommendation-statement
#10
Susan J Curry, Alex H Krist, Douglas K Owens, Michael J Barry, Aaron B Caughey, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Martha Kubik, C Seth Landefeld, Carol M Mangione, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng, John B Wong
Importance: Peripheral artery disease (PAD) is a manifestation of atherosclerosis in the lower limbs. It can impair walking and, in severe cases, can lead to tissue loss, infection, and amputation. In addition to morbidity directly caused by PAD, patients with PAD are at increased risk for cardiovascular disease (CVD) events, because atherosclerosis is a systemic disease that also causes coronary and cerebrovascular events. Objective: To update the 2013 US Preventive Services Task Force (USPSTF) recommendation on screening for PAD and CVD risk with the ankle-brachial index (ABI)...
July 10, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29994232/blood-triglyceride-monitoring-with-smartphone-as-electrochemical-analyzer-for-cardiovascular-disease-prevention
#11
Jian Wang, Xiwei Huang, Shiyang Tang, Gongming Shi, Xing Ma, Jinhong Guo
Nowadays, cardiovascular diseases have become one of the most risks threating human being's life in the world. The early screening and efficient management of cardiovascular diseases are critically important to extend the patients' life. Blood lipid level is a key biochemical factor used to estimate the cardiovascular disease in clinical situation. Triglyceride as one important blood lipid plays an indispensable role in the blood test. On the other hand, smartphone has unprecedentedly large scale users since the last decade, which paves the wide avenue for the dissemination of smartphone-associated medical devices...
June 11, 2018: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/29993172/cardiovascular-and-metabolic-comorbidities-in-patients-with-alzheimer-s-disease-and-vascular-dementia-compared-to-a-psychiatric-control-cohort
#12
Jonathan Vogelgsang, Claus Wolff-Menzler, Bernhard Kis, Mona Abdel-Hamid, Jens Wiltfang, Philipp Hessmann
BACKGROUND: Multimorbidity in dementia is associated with an increased risk of complications and a higher need for care. Having knowledge of cardiovascular and metabolic comorbidities is crucial when making decisions about diagnostic procedures and therapies. We compared the prevalence of comorbidities in hospitalized patients with Alzheimer's disease (AD), vascular dementia, and psychiatric diseases other than dementia. Additionally, we compared clinically relevant health-care indicators (length of hospital stay, rate of re-hospitalization) between these groups...
July 11, 2018: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/29992191/delivery-of-public-health-services-by-community-health-workers-chws-in-primary-health-care-settings-in-china-a-systematic-review-1996-2016
#13
Wenting Huang, Hongfei Long, Jiang Li, Sha Tao, Pinpin Zheng, Shenglan Tang, Abu S Abdullah
Background: Community Health Workers (CHWs) have been widely used in response to the shortage of skilled health workers especially in resource limited areas. China has a long history of involving CHWs in public health intervention project. CHWs in China called village doctors who have both treatment and public health responsibilities. This systematic review aimed to identify the types of public health services provided by CHWs and summarized potential barriers and facilitating factors in the delivery of these services...
2018: Global Health Research and Policy
https://www.readbyqxmd.com/read/29989911/economic-outcomes-of-a-precision-medicine-blood-test-to-assess-obstructive-coronary-artery-disease-results-from-the-preset-registry
#14
Joseph A Ladapo, Matthew J Budoff, Pejman Azarmina, David Sharp, Alice Baker, Bruce Maniet, Lee Herman, Mark Monane
PURPOSE: The evaluation of obstructive coronary artery disease (CAD) is inefficient and costly. Previous studies of an age/sex/gene expression score (ASGES) in this diagnostic workup have shown a 96% negative predictive value, as well as an 85% decreased likelihood of cardiac referral among low-score outpatients at 45 days. The objective was to explore the one-year cost implications of ASGES use among symptomatic outpatients. DESIGN: A prospective PRESET Registry (NCT01677156) enrolled stable, nonacute adult patients presenting with symptoms suggestive of obstructive CAD at 21 U...
June 2018: Managed Care
https://www.readbyqxmd.com/read/29988604/public-health-implications-of-overscreening-for-carotid-artery-stenosis-prediabetes-and-thyroid-cancer
#15
REVIEW
Bich-May Nguyen, Kenneth W Lin, Ranit Mishori
Background: Overscreening occurs when people without symptoms undergo tests for diseases and the results will not improve their health. In this commentary, we examine three examples of how campaigns to screen and treat specific vascular, metabolic, and oncologic diseases in asymptomatic individuals have produced substantial overdiagnosis and may well have contributed to more harm than good. These conditions were chosen because they may not be as well known as other cases such as screening for breast or prostate cancer...
2018: Public Health Reviews
https://www.readbyqxmd.com/read/29988602/the-charms-pilot-study-a-multi-method-assessment-of-the-feasibility-of-a-sexual-counselling-implementation-intervention-in-cardiac-rehabilitation-in-ireland
#16
Patrick J Murphy, Chris Noone, Maureen D'Eath, Dympna Casey, Sally Doherty, Tiny Jaarsma, Andrew W Murphy, Martin O'Donnell, Noeleen Fallon, Paddy Gillespie, Amirhossein Jalali, Jenny Mc Sharry, John Newell, Elaine Toomey, Elaine E Steinke, Molly Byrne
Background: Many people living with cardiovascular disease (CVD) are affected by sexual problems associated with the condition. International guidelines recommend all patients with CVD should receive sexual counselling, yet this is rarely provided by health professionals. The current study piloted the Cardiac Health and Relationship Management and Sexuality (CHARMS) intervention, a complex multi-level intervention designed to increase the implementation of sexual counselling guidelines in hospital-based cardiac rehabilitation (CR) in Ireland...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29988313/cardiovascular-diseases-monitoring-lessons-from-population-based-registries-to-address-future-opportunities-and-challenges-in-europe
#17
Luigi Palmieri, Giovanni Veronesi, Giovanni Corrao, Giuseppe Traversa, Marco M Ferrario, Giovanni Nicoletti, Anna Di Lonardo, Chiara Donfrancesco, Flavia Carle, Simona Giampaoli
Background: Population-based registries implement the comprehensive collection of all disease events that occur in a well-characterized population within a certain time period and represent the preferred tools for disease monitoring at a population level. Main characteristics of a Population-based registry are to provide answers to defined research questions, also related to clinical and health policy purposes, assuring completeness of event identification, and implementing a process of case adjudication (validation) according to standardised diagnostic criteria...
2018: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29985946/knowledge-attitude-and-practice-on-diet-and-physical-activity-among-mothers-with-young-children-in-the-jhaukhel-duwakot-health-demographic-surveillance-site-nepal
#18
Natalia Oli, Abhinav Vaidya, Katja Pahkala, Gabriele Eiben, Alexandra Krettek
The prevalence of cardiovascular diseases is increasing in low and middle-income countries; Nepal's population shows a high prevalence of behavioral risk factors. Our cross-sectional study in the Jhaukhel-Duwakot Health Demographic Surveillance Site (JD-HDSS), located near the capital Kathmandu, explored knowledge, attitude, and practice (KAP) of mothers with young children regarding diet and physical activity and mothers' perception of their children's attitude and behavior toward the same issues. The purpose of our study was to assess needs of the mothers concerning cardiovascular health in general and more specifically regarding diet and physical activity, and to establish a baseline for future intervention in the community by comparing two villages of JD-HDSS...
2018: PloS One
https://www.readbyqxmd.com/read/29984667/statins-pharmacokinetics-pharmacodynamics-and-cost-effectiveness-analysis
#19
Gabriella Ricci, Marco Matteo Ciccone, Paola Giordano, Francesca Cortese
Cardiovascular diseases secondary to atherosclerosis are the primary causes of early death and disability worldwide and dyslipidaemia represents one of the most important modifiable risk factors. Among lipid abnormalities that define it, low-density lipoprotein cholesterol (LDL-C) is the primary target of therapy, since multiple randomized controlled trials have shown the positive impact of its reduction on atherosclerosis development. For their ability to lower LDL-C levels, statins are the most studied drugs in cardiovascular disease prevention, of proven utility in slowing the progression or even determining regression of atherosclerosis...
July 6, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29983644/primary-and-secondary-prevention-interventions-for-cardiovascular-disease-in-low-income-and-middle-income-countries-a-systematic-review-of-economic-evaluations
#20
REVIEW
Leopold Ndemnge Aminde, Noah Fongwen Takah, Belen Zapata-Diomedi, J Lennert Veerman
Background: Cardiovascular disease (CVD) is the leading cause of deaths globally, with greatest premature mortality in the low- and middle-income countries (LMIC). Many of these countries, especially in sub-Saharan Africa, have significant budget constraints. The need for current evidence on which interventions offer good value for money to stem this CVD epidemic motivates this study. Methods: In this systematic review, we included studies reporting full economic evaluations of individual and population-based interventions (pharmacologic and non-pharmacologic), for primary and secondary prevention of CVD among adults in LMIC...
2018: Cost Effectiveness and Resource Allocation: C/E
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