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Whey supplement

Masahiro Kita, Kuniaki Obara, Sumio Kondo, Satoshi Umeda, Yasuhisa Ano
Background: Previous epidemiological and clinical studies have shown that dairy products have beneficial effects on cognitive decline and dementia. Enzymatic digestion of whey protein produces a whey peptide rich in tryptophan-tyrosine-related peptides which improve cognitive performance in mice. We evaluated the effects of whey peptides on cognitive functions in healthy adults in a randomized, double-blind, placebo-controlled design. Methods: 101 healthy adults (45 to 64 years), with a self-awareness of cognitive decline received either whey peptide or placebo supplements for 12 weeks...
July 13, 2018: Nutrients
Caroline Giezenaar, Natalie D Luscombe-Marsh, Amy T Hutchison, Kylie Lange, Trygve Hausken, Karen L Jones, Michael Horowitz, Ian Chapman, Stijn Soenen
BACKGROUND/OBJECTIVES: Protein supplements, usually drinks rich in whey protein, are used widely for weight loss purposes in overweight adults. Information comparing the effects of whey protein on appetite and energy intake in men and women is limited. The objective was to compare the acute effects of whey-protein intake on energy intake, appetite, gastric emptying and gut hormones in healthy young men and women. SUBJECTS/METHODS: Gastric emptying (3D-ultrasonography), blood glucose and plasma insulin, glucagon, ghrelin, cholecystokinin (CCK), gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) concentrations (0-180 min), appetite (visual analogue scales), and ad libitum energy intake from a buffet meal (180-210 min) were determined after ingestion of 30 g (120 kcal) or 70 g (280 kcal) whey protein, or a flavoured-water control drink (~2 kcal) in 8 healthy young men (25 ± 2 y, 72 ± 3 kg, 23 ± 1 kg/m2 ) and 8 women (23 ± 1 y, 64 ± 2 kg, 24 ± 0...
July 13, 2018: Nutrition & Diabetes
K Naidoo, R Naidoo, V Bangalee
The South African sport supplement industry has experienced rapid growth in recent years. Despite the massive market demand, this industry remains poorly regulated. From raw ingredient contamination to label compliance discrepancies, the sport supplement industry is an area of growing concern and warrants further public debate.
February 27, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Julien Sauser, Sophie Nutten, Nanda de Groot, Sophie Pecquet, Dagmar Simon, Hans-Uwe Simon, Jonathan M Spergel, Sibylle Koletzko, Carine Blanchard
Limited evidence is available regarding the effect of partially hydrolyzed whey-based formula (pHF-W) on growth and atopic dermatitis (AD) risk reduction in infants within the general infant population, and without a familial history of allergy as an inclusion or exclusion criterion. We reviewed the current evidence available from studies using pHF-W in the general population and summarized the data on safety (growth) and efficacy outcomes (reduction of AD), comparing the studies side by side. A total of 8 clinical trials were identified from the literature search, 7 of which used the same pHF-W...
July 12, 2018: International Archives of Allergy and Immunology
Karl E Cogan, Brendan Egan
PURPOSE: Acute protein co-ingestion or a single bout of aerobic exercise can attenuate postprandial glycemia, but their combined effect has not been investigated in type 2 diabetics. METHODS: Using a randomised crossover design, male type 2 diabetics (n = 8) [mean (95% CI); age, 55.0 (45.2, 64.8) year; BMI, 33.7 (25.6, 41.8) kg·m- 2 ; 2 h glucose 14.0 (12.5, 15.5) mM] completed (1) 75 g oral glucose tolerance test (OGTT) (CON); (2) OGTT supplemented with 0...
July 6, 2018: European Journal of Applied Physiology
C Moran, A Scotto di Palumbo, J Bramham, A Moran, B Rooney, G De Vito, B Egan
OBJECTIVES: To investigate the impact of a six-month multi-ingredient nutrition supplement intervention (Smartfish®), containing omega-3 polyunsaturated fatty acids (PUFAs), vitamin D, resveratrol, and whey protein, on cognitive function in Irish older adults. DESIGN: Double-blind, randomised controlled trial ( NCT02001831). A quantitative, mixed-model design was employed in which the dependent variable (cognitive function) was analysed with a between-subjects factor of group (placebo, intervention) and within-subjects factor of testing occasion (baseline, three-months, six-months)...
2018: Journal of Prevention of Alzheimer's Disease
Mónica Costas Malvido, Elisa Alonso González, David Outeiriño, Nelson Pérez Guerra
In this study, probiotic biomass and nisin productions by Lactococcus lactis CECT 539 were followed in two realkalized fed-batch cultures in diluted whey (DW) supplemented with KH2 PO4 up to a total phosphorus concentration of 0.459 g/L. Increased biomass (5.12 g/L, 2.18 × 1010 CFU/mL) and nisin (235.23 BU/mL) concentrations were obtained in the culture fed concentrated whey and concentrated mussel processing waste (CMPW) medium supplemented with glucose up to a concentration of 400 g/L (CMPW + G medium) compared with similar fed-batch fermentations in DW medium...
July 2018: 3 Biotech
Hans-Jürgen Heidebrecht, José Toro-Sierra, Ulrich Kulozik
The use of bioactive bovine milk immunoglobulins (Ig) has been found to be an alternative treatment for certain human gastrointestinal diseases. Some methodologies have been developed with bovine colostrum. These are considered in laboratory scale and are bound to high cost and limited availability of the raw material. The main challenge remains in obtaining high amounts of active IgG from an available source as mature cow milk by the means of industrial processes. Microfiltration (MF) was chosen as a process variant, which enables a gentle and effective concentration of the Ig fractions (ca...
June 28, 2018: Foods (Basel, Switzerland)
Elizabeth Ignowski, Aimee N Winter, Nathan Duval, Holly Fleming, Tyler Wallace, Evan Manning, Lilia Koza, Kendra Huber, Natalie J Serkova, Daniel A Linseman
Traumatic brain injury (TBI)1 is a major public health problem estimated to affect nearly 1.7 million people in the United States annually. Due to the often debilitating effects of TBI, novel preventative agents are highly desirable for at risk populations. Here, we tested a whey protein supplement, Immunocal®, for its potential to enhance resilience to TBI. Immunocal® is a non-denatured whey protein preparation which has been shown to act as a cysteine delivery system to increase levels of the essential antioxidant glutathione (GSH)...
June 22, 2018: Free Radical Biology & Medicine
Ana Batista, Cristina P Monteiro, Rute Borrego, Catarina N Matias, Filipe J Teixeira, Maria João Valamatos, Ana Cláudia Oliveira, Joana F Reis, Lino Mendes, Luís B Sardinha
The purpose of this study was to evaluate the association between whey protein supplementation, body composition and muscle strength, in resistance-trained individuals. Forty-nine healthy males, aged 18 to 35 years that were engaged in resistance training for at least one year, were assigned into two groups according to whey protein intake (Whey: n=26, 30.7 ± 7.4 yr, 75.8 ± 9.0 kg; WithoutWhey: n=23, 31.0 ± 7.4 yr, 77.9 ± 9.3 kg). Using a cross-sectional design, a morning assessment of body fat mass (FM) (by dual energy X-ray absorptiometry) and strength (using 1RM for bench press and back squat) was performed...
June 15, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Gethin H Evans, Lewis Mattin, Isabelle Ireland, William Harrison, Adora M W Yau, Victoria McIver, Tristan Pocock, Elizabeth Sheader, Lewis J James
Whey protein is a commonly ingested nutritional supplement amongst athletes and regular exercisers; however, its role in post-exercise rehydration remains unclear. Eight healthy male and female participants completed two experimental trials involving the ingestion of 35 g of whey protein (WP) or maltodextrin (MD) at the onset of a rehydration period, followed by ingestion of water to a volume equivalent to 150% of the amount of body mass lost during exercise in the heat. The gastric emptying rates of the solutions were measured using 13 C breath tests...
June 14, 2018: Nutrients
Michaela C Devries, Chris McGlory, Douglas R Bolster, Alison Kamil, Maike Rahn, Laura Harkness, Steven K Baker, Stuart M Phillips
Background: Older adults show a blunted muscle protein synthesis (MPS) response to postprandial hyperaminoacidemia relative to younger adults. Evidence suggests that this anabolic resistance can be overcome by consuming greater quantities of leucine. Objective: The purpose of this trial was to determine whether the addition of leucine to a smaller dose (10 g) of milk proteins would, when compared with a larger dose (25 g) of whey protein isolate (WPI), result in similar increases in acute (hourly) and integrated (daily) myofibrillar protein synthesis (myoPS)...
July 1, 2018: Journal of Nutrition
Sarah R Jackman, Matthew S Brook, Richard M Pulsford, Emma J Cockcroft, Matthew I Campbell, Debbie Rankin, Philip Atherton, Kenneth Smith, Joanna L Bowtell
BACKGROUND: Oxidative stress and inflammation may contribute to anabolic resistance in response to protein and exercise in older adults. We investigated whether consumption of montmorency cherry concentrate (MCC) increased anabolic sensitivity to protein ingestion and resistance exercise in healthy older men. METHODS: Sixteen healthy older men were randomized to receive MCC (60 mL·d-1 ) or placebo (PLA) for two weeks, after baseline measures in week 1. During week 3, participants consumed 10 g whey protein·d-1 and completed three bouts of unilateral leg resistance exercise (4 × 8-10 repetitions at 80% 1RM)...
June 8, 2018: Experimental Gerontology
Tim Snijders, Kirsten E Bell, Joshua P Nederveen, Nelson I Saddler, Nicole Mazara, Dinesh A Kumbhare, Stuart M Phillips, Gianni Parise
Background: Nutritional supplementation can have beneficial effects on body composition, strength, and function in older adults. However, whether the response of satellite cells can be altered by nutritional supplementation in older adults remains unknown. Objective: We assessed whether a multi-ingredient protein-based supplement taken over a prolonged period of time could alter the muscle satellite cell response after exercise in older men. Methods: Twenty-seven older men [mean ± SD age: 73 ± 1 y; mean ± SD body mass index (kg/m2): 28 ± 1] participated in a randomized double-blind experiment...
June 1, 2018: Journal of Nutrition
Takamitsu Tsukahara, Takio Inatomi, Konosuke Otomaru, Masaaki Amatatsu, Gustavo A Romero-Pérez, Ryo Inoue
We investigated if probiotic supplementation could improve the health and reproductive performance of unvaccinated lactating sows infected with porcine epidemic diarrhea (PED) virus. Twenty unvaccinated pregnant sows were equally allocated to probiotic-supplemented (P) and control (C) groups. For the experiment, 15 g/day of probiotic compound BIO-THREE PZ was given to P sows. Reproductive performance was checked daily. The number of neonates fostered by each sow was maintained at eight throughout the experiment...
May 27, 2018: Animal Science Journal, Nihon Chikusan Gakkaihō
Asmaa T Y Kishawy, Shimaa A Amer, Ali Osman, Shafika A M Elsayed, Mohamed E Abd El-Hack, Ayman A Swelum, Hani Ba-Awadh, Islam M Saadeldin
The present study evaluated the impact of supplementing the rabbit diet with graded levels of whey powder and citric acid. The dietary treatments were as follows: T1, control diet (basal diet); T2, basal diet + 10 g/kg citric acid; T3, T2 + whey powder (7.5 g/kg); T4, T2 + whey powder (15 g/kg); and T5, T2 + whey powder (22.5 g/kg). Results, the T5 diet resulted in the best (P < 0.05) final body weight, body weight gain, feed conversion ratio, protein efficiency, relative growth rate, and dressed weight...
May 23, 2018: AMB Express
Rabin Gyawali, Salam A Ibrahim
The objective of the study reported in this Research Communication was to investigate the effects of pectin and whey protein concentrate (WPC) on the generation of acid whey during Greek-style yogurt (GSY) processing. Yogurt samples were prepared using pectin (0·05%, w/v) and whey protein concentrate (WPC-80) (1%, w/v) as possible ingredients that reduce the acid whey production. Control yogurt sample was prepared without addition of these ingredients. The results showed that yogurt made with pectin plus WPC had significantly higher water holding capacity (~56%) than the control (33%)...
May 2018: Journal of Dairy Research
Sharmela Sahathevan, Chee-Hee Se, SeeHoe Ng, Ban-Hock Khor, Karuthan Chinna, Bak Leong Goh, Halim A Gafor, Sunita Bavanandan, Ghazali Ahmad, Tilakavati Karupaiah
BACKGROUND AND AIMS: Poor dietary intake is commonly associated with malnutrition in the dialysis population and oral nutritional supplementation is strategized to redress dietary inadequacy. Knowledge on clinical efficacy of whey protein supplementation (WPS) as an option to treat malnutrition in continuous ambulatory peritoneal dialysis (CAPD) patients is limited. METHODS: This multicenter, parallel, open-label, randomized controlled trial investigated the clinical efficacy of WPS in 126 malnourished CAPD patients with serum albumin <40 g/L and body mass index (BMI) <24 kg/m2 ...
June 2018: Clinical Nutrition ESPEN
Rodrigo R Fernandes, Hellen C G Nabuco, Paulo Sugihara Junior, Edilaine F Cavalcante, Paolo M C Fabro, Crisieli M Tomeleri, Alex S Ribeiro, Décio S Barbosa, Danielle Venturini, Brad J Schoenfeld, Edilson S Cyrino
OBJECTIVE: The aim of this study was to analyze the effects of higher protein (HP) intake associated with resistance training (RT) on parameters of cardiometabolic risk disease (CMR). METHODS: A randomized, double-blind and placebo-controlled design was conducted. Thirty-two pre-conditioned older women were randomized in two groups to receive 35 g of protein (high protein group - HP) or 35 g of placebo (low protein group - LP) after training sessions. The RT program was carried out over 12 weeks, 3 days per week and 3 sets of 8-12 repetitions...
May 9, 2018: Experimental Gerontology
Hellen C G Nabuco, Crisieli M Tomeleri, Paulo Sugihara Junior, Rodrigo R Fernandes, Edilaine F Cavalcante, Melissa Antunes, Alex S Ribeiro, Denilson C Teixeira, Analiza M Silva, Luís B Sardinha, Edilson S Cyrino
Aging is associated with sarcopenia and dynapenia, with both processes contributing to functional dependence and mortality in older adults. Resistance training (RT) and increased protein intake are strategies that may contribute to health improvements in older adults. Therefore, the aim was to investigate the effects of whey protein (WP) supplementation consumed either immediately pre- or post-RT on skeletal muscle mass (SMM), muscular strength, and functional capacity in pre-conditioned older women. Seventy older women participated in this investigation and were randomly assigned to one of three groups: whey protein pre-RT and placebo post-RT (WP-PLA, n = 24), placebo pre-RT and whey protein post-RT (PLA-WP, n = 23), and placebo pre- and post-RT (PLA-PLA, n = 23)...
May 3, 2018: Nutrients
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