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https://www.readbyqxmd.com/read/28636003/in-vitro-modulation-of-gut-microbiota-by-whey-protein-to-preserve-intestinal-health
#1
T Sánchez-Moya, R López-Nicolás, D Planes, C A González-Bermúdez, G Ros-Berruezo, C Frontela-Saseta
The effect of several types of whey milk - cow, sheep, goat and a mixture of them (60 : 20 : 20, respectively) - was assessed in the human gut microbiota. The prebiotic potential of these substrates was evaluated through in vitro gastrointestinal digestion following faecal batch culture fermentations (mimicking colonic fermentation) for 48 hours, using faeces from normal-weight (NW) and obese (OB) donors. Throughout the fermentation process, pH, gas production, short chain and branched fatty acids (SCFA-BCFA) were measured, as well as the changes of microbiota using qPCR...
June 21, 2017: Food & Function
https://www.readbyqxmd.com/read/28620481/tolerability-and-safety-of-the-intake-of-bovine-milk-oligosaccharides-extracted-from-cheese-whey-in-healthy-human-adults
#2
Jennifer T Smilowitz, Danielle G Lemay, Karen M Kalanetra, Elizabeth L Chin, Angela M Zivkovic, Melissa A Breck, J Bruce German, David A Mills, Carolyn Slupsky, Daniela Barile
Mechanistic research suggests a unique evolutionary relationship between complex milk oligosaccharides and cognate bifidobacteria enriched in breast-fed infants. Bovine milk oligosaccharides (BMO) were recently identified as structurally and functionally similar to human milk oligosaccharides. The present single-blind three-way crossover study is the first to determine the safety and tolerability of BMO consumption by healthy human participants (n 12) and its effects on faecal microbiota and microbial metabolism...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28603087/cysteine-rich-whey-protein-isolate-immunocal%C3%A2-ameliorates-deficits-in-the-gfap-hmox1-mouse-model-of-schizophrenia
#3
Wei Song, Ayda Tavitian, Marisa Cressatti, Carmela Galindez, Adrienne Liberman, Hyman M Schipper
Schizophrenia is a neuropsychiatric disorder that features neural oxidative stress and glutathione (GSH) deficits. Oxidative stress is augmented in brain tissue of GFAP.HMOX1 transgenic mice which exhibit schizophrenia-relevant characteristics. The whey protein isolate, Immunocal® serves as a GSH precursor upon oral administration. In this study, we treated GFAP.HMOX1 transgenic mice daily with either Immunocal (33mg/ml drinking water) or equivalent concentrations of casein (control) between the ages of 5 and 6...
June 8, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28591764/a-randomized-controlled-pilot-trial-of-interventions-to-improve-functional-recovery-after-hospitalization-in-older-adults-feasibility-and-adherence
#4
Rachel R Deer, Shawn M Goodlett, Steve R Fisher, Jacques Baillargeon, Jared M Dickinson, Mukaila Raji, Elena Volpi
Background.: Hospitalization is a major risk factor for functional decline, disability, loss of independence, and mortality in older adults. Evidence-based interventions to improve functional recovery from hospitalization are difficult to evaluate and implement in geriatric patients. The goal of this pilot study was to test the feasibility of recruiting geriatric inpatients and implementing pragmatic interventions to improve physical function following hospitalization. Methods...
June 7, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28577554/fermentation-of-lactose-to-ethanol-in-cheese-whey-permeate-and-concentrated-permeate-by-engineered-escherichia-coli
#5
Lorenzo Pasotti, Susanna Zucca, Michela Casanova, Giuseppina Micoli, Maria Gabriella Cusella De Angelis, Paolo Magni
BACKGROUND: Whey permeate is a lactose-rich effluent remaining after protein extraction from milk-resulting cheese whey, an abundant dairy waste. The lactose to ethanol fermentation can complete whey valorization chain by decreasing dairy waste polluting potential, due to its nutritional load, and producing a biofuel from renewable source at the same time. Wild type and engineered microorganisms have been proposed as fermentation biocatalysts. However, they present different drawbacks (e...
June 2, 2017: BMC Biotechnology
https://www.readbyqxmd.com/read/28566814/endocrine-responses-and-acute-mtor-pathway-phosphorylation-to-resistance-exercise-with-leucine-and-whey
#6
M T Lane, T J Herda, A C Fry, M A Cooper, M J Andre, P M Gallagher
Leucine ingestion reportedly activates the mTOR pathway in skeletal muscle, contributing to a hypertrophy response. The purpose of the study was to compare the post-resistance exercise effects of leucine and whey protein supplementation on endocrine responses and muscle mTOR pathway phosphorylation. On visit 1, subjects (X±SD; n=20; age=27.8±2.8yrs) provided baseline blood samples for analysis of cortisol, glucose and insulin; a muscle biopsy of the vastus lateralis muscle to assess mTOR signaling pathway phosphorylation; and were tested for maximum strength on the leg press and leg extension exercises...
June 2017: Biology of Sport
https://www.readbyqxmd.com/read/28557663/dietary-supplement-intake-and-associated-factors-among-gym-users-in-a-university-community
#7
Amita Attlee, Amina Haider, Asma Hassan, Noura Alzamil, Mona Hashim, Reyad Shaker Obaid
Dietary supplement intake and associated factors among gym users in a university community in Sharjah, United Arab Emirates (UAE), were assessed using a structured, self-administered questionnaire in this cross-sectional study. Adults (N = 320) from five gyms in the University City of Sharjah participated in this cross-sectional study. The prevalence of dietary supplement intake was 43.8%. Statistically significant associations were found between the use of dietary supplements and sex (47.7% males, 28.1% females; p = ...
May 30, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28542713/withdrawn-infant-formulas-containing-hydrolysed-protein-for-prevention-of-allergic-disease-and-food-allergy
#8
REVIEW
David A Osborn, John Kh Sinn, Lisa J Jones
BACKGROUND: Allergy is common and may be associated with foods, including cow's milk formula (CMF). Formulas containing hydrolysed proteins have been used to treat infants with allergy. However, it is unclear whether hydrolysed formulas can be advocated for prevention of allergy in infants. OBJECTIVES: To compare effects on allergy and food allergy when infants are fed a hydrolysed formula versus CMF or human breast milk. If hydrolysed formulas are effective, to determine what type of hydrolysed formula is most effective, including extensively or partially hydrolysed formula (EHF/PHF)...
May 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28530448/carbohydrates-alone-or-mixing-with-beef-or-whey-protein-promote-similar-training-outcomes-in-resistance-training-males-a-double-blind-randomized-controlled-clinical-trial
#9
Fernando Naclerio, Marco Seijo-Bujia, Eneko Larumbe-Zabala, Conrad P Earnest
Beef powder is a new high-quality protein source scarcely researched relative to exercise performance. The present study examined the impact of ingesting hydrolyzed beef protein, whey protein, and carbohydrate on strength performance (1RM), body composition (via plethysmography), limb circumferences and muscular thickness (via ultrasonography), following an 8-week resistance-training program. After being randomly assigned to one of the following groups: Beef, Whey, or Carbohydrate, twenty four recreationally physically active males (n=8 per treatment) ingested 20 g of supplement, mixed with orange juice, once a day (immediately after workout or before breakfast)...
May 22, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28492492/the-effect-of-dietary-glycemic-properties-on-markers-of-inflammation-insulin-resistance-and-body-composition-in-postmenopausal-american-women-an-ancillary-study-from-a-multicenter-protein-supplementation-trial
#10
Violeta Stojkovic, Christine A Simpson, Rebecca R Sullivan, Anna Maria Cusano, Jane E Kerstetter, Anne M Kenny, Karl L Insogna, Jessica D Bihuniak
Controversy exists as to whether high glycemic index/glycemic load (GI/GL) diets increase the risk of chronic inflammation, which has been postulated as a pathogenic intermediary between such diets and age-related alterations in body composition and insulin resistance. We conducted an ancillary study to a randomized, double-blind trial comparing the effects of a whey protein supplement (PRO, n = 38) and a maltodextrin supplement (CHO, n = 46) on bone density to evaluate the impact of a calibrated increase in GI/GL on inflammation, insulin resistance, and body composition in a healthy aging population...
May 11, 2017: Nutrients
https://www.readbyqxmd.com/read/28483498/design-of-a-randomized-trial-to-determine-the-optimum-protein-intake-to-preserve-lean-body-mass-and-to-optimize-response-to-a-promyogenic-anabolic-agent-in-older-men-with-physical-functional-limitation
#11
Shalender Bhasin, Caroline M Apovian, Thomas G Travison, Karol Pencina, Grace Huang, Lynn L Moore, Wayne W Campbell, Andrew Howland, Ruo Chen, Martha R Singer, Mitali Shah, Richard Eder, Haley Schram, Richelle Bearup, Yusnie M Beleva, Ashley C McCarthy, Zhouying Li, Erin Woodbury, Jennifer McKinnon, Thomas W Storer, Shehzad Basaria
The dietary protein allowance for older men to maintain lean body mass and muscle strength and to accrue optimal anabolic responses to promyogenic stimuli is poorly characterized. The OPTIMEN trial was designed to assess in older men with moderate physical dysfunction and insufficient habitual protein intake (<recommended dietary allowance, RDA, 0.8g·kg(-1)·d(-1)) the efficacy of consuming diets containing 163% RDA (1.3g·kg(-1)·d(-1)) for protein, compared to RDA, to increase lean mass, muscle performance, and physical function...
July 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28480079/prevalence-of-dietary-supplements-use-among-gymnasium-users
#12
Ayman H Jawadi, Abdulmalik M Addar, Abdulaziz S Alazzam, Fahad O Alrabieah, Abdullah S Al Alsheikh, Roaa R Amer, Al Anoud S Aldrees, Maha A Al Turki, Ali K Osman, Motasim Badri
Background. Several studies showed that regular gymnasium users use various dietary supplements without comprehension of their potential risks. Objective. To determine the prevalence and dietary supplement intake and assess the awareness of supplement use among regular gymnasium users in Riyadh, Saudi Arabia. Methods. A descriptive cross-sectional study was conducted among regular gymnasium users in Riyadh, Saudi Arabia, between April 2015 and June 2015. A validated structured questionnaire was used. Results...
2017: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28458804/nutrition-pharmacological-and-training-strategies-adopted-by-six-bodybuilders-case-report-and-critical-review
#13
Paulo Gentil, Claudio Andre Barbosa de Lira, Antonio Paoli, José Alexandre Barbosa Dos Santos, Roberto Deivide Teixeira da Silva, José Romulo Pereira Junior, Edson Pereira da Silva, Rodrigo Ferro Magosso
The purpose of this study was to report and analyze the practices adopted by bodybuilders in light of scientific evidence and to propose evidence-based alternatives. Six (four male and two female) bodybuilders and their coaches were directly interviewed. According to the reports, the quantity of anabolic steroids used by the men was 500-750 mg/week during the bulking phase and 720-1160 mg during the cutting phase. The values for women were 400 and 740 mg, respectively. The participants also used ephedrine and hydrochlorothiazide during the cutting phase...
February 24, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/28443026/short-term-effects-of-lupin-vs-whey-supplementation-on-glucose-and-insulin-responses-to-a-standardized-meal-in-a-randomized-cross-over-trial
#14
Kathrin Schopen, Ann C Ewald, Bernd W Johannes, Wilhelm Bloch, Jörn Rittweger, Petra Frings-Meuthen
Background: Whey protein is known to reduce postprandial glycaemia in people with type 2 diabetes mellitus. Lupin as a vegetable source of protein could be considered as an alternative, as the percentage of vegetarian and vegan consumers is raising. The present study compares the acute glycemic effects of whey and lupin in healthy volunteers following a carbohydrate-rich reference meal. Methods In cross-over design, three standardized meals (reference meal; reference meal + whey; reference meal + lupin) were provided to 12 healthy male and female volunteers, aged between 23 and 33, in a balanced, randomized order...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28433470/daily-supplementation-of-dietary-protein-improves-the-metabolic-effects-of-glp-1-based-pharmacotherapy-in-lean-and-obese-rats
#15
Elizabeth G Mietlicki-Baase, Kieran Koch-Laskowski, Lauren E McGrath, Joanna Krawczyk, Tram Pham, Rinzin Lhamo, David J Reiner, Matthew R Hayes
Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from intestinal L-cells in response to food entering into the gastrointestinal tract. GLP-1-based pharmaceuticals improve blood glucose regulation and reduce feeding. Specific macronutrients, when ingested, may trigger GLP-1 secretion and enhance the effects of systemic sitagliptin, a pharmacological inhibitor of DPP-IV (an enzyme that rapidly degrades GLP-1). In particular, macronutrient constituents found in dairy foods may act as potent secretagogues for GLP-1, and acute preclinical trials show that ingestion of dairy protein may represent a promising adjunct behavioral therapy in combination with sitagliptin...
August 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28422532/effects-of-post-exercise-protein-intake-on-muscle-mass-and-strength-during-resistance-training-is-there-an-optimal-ratio-between-fast-and-slow-proteins
#16
Marina Fabre, Christophe Hausswirth, Eve Tiollier, Odeline Molle, Julien Louis, Alexandre Durguerian, Nathalie Neuveux, Xavier Bigard
While effects of the two classes of proteins found in milk (i.e. soluble proteins, including whey, and casein) on muscle protein synthesis have been well investigated after a single bout of resistance exercise (RE), the combined effects of these two proteins on the muscle responses to resistance training (RT) have not yet been investigated. Therefore, the aim of this study was to examine the effects of protein supplementation varying by the ratio between milk soluble proteins (fast-digested protein) and casein (slow-digested protein) on the muscle to a 9-week RT program...
April 19, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28415067/effect-of-whey-protein-in-conjunction-with-a-caloric-restricted-diet-and-resistance-training
#17
Wesley D Dudgeon, Elizabeth P Kelley, Timothy P Scheett
Dudgeon, WD, Kelley, EP, and Scheett, TP. Effect of whey protein in conjunction with a caloric-restricted diet and resistance training. J Strength Cond Res 31(5): 1353-1361, 2017-Caloric-restricted weight loss, especially rapid weight loss, results from a decrease in both lean and fat mass (FM). The goal for many is to lose FM while retaining lean body mass (LBM) and muscular performance thus many turn to supplements. Sixteen resistance-trained men (24 ± 1.6 years of age) completed a 4 d·wk body building style split resistance training program for 8 weeks in conjunction with a pre-exercise, periexercise, and postexercise ingestion of whey protein (WHEY) nutritional supplement or carbohydrate (CON)-based nutritional supplement...
May 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28397754/oral-supplementation-with-bovine-colostrum-decreases-intestinal-permeability-and-stool-concentrations-of-zonulin-in-athletes
#18
Maciej Hałasa, Dominika Maciejewska, Magdalena Baśkiewicz-Hałasa, Bogusław Machaliński, Krzysztof Safranow, Ewa Stachowska
Increased intestinal permeability has been implicated in various pathologies, has various causes, and can develop during vigorous athletic training. Colostrum bovinum is a natural supplement with a wide range of supposed positive health effects, including reduction of intestine permeability. We assessed influence of colostrum supplementation on intestinal permeability related parameters in a group of 16 athletes during peak training for competition. This double-blind placebo-controlled study compared supplementation for 20 days with 500 mg of colostrum bovinum or placebo (whey)...
April 8, 2017: Nutrients
https://www.readbyqxmd.com/read/28382342/impact-of-whey-proteins-on-the-systemic-and-local-intestinal-level-of-mice-with-diet-induced-obesity
#19
D Swiątecka, D Złotkowska, L H Markiewicz, A M Szyc, B Wróblewska
Obesity is a serious public health problem and being multifactorial is difficult to tackle. Since the intestinal ecosystem's homeostasis is, at least partially, diet-dependent, its modulation may be triggered by food components that are designed to exert a modulatory action leading to a health-promoting effect. Milk whey proteins, are considered as such promising factors since they influence satiation as well as body weight and constitute the source of biologically active peptides which may modulate health status locally and systemically...
April 19, 2017: Food & Function
https://www.readbyqxmd.com/read/28382336/supplementation-of-fermented-maillard-reactive-whey-protein-enhances-immunity-by-increasing-nk-cell-activity
#20
Miso Kang, Nam Su Oh, Minjoo Kim, Hyeon Yeong Ahn, Hye Jin Yoo, Minghan Sun, Shin-Ho Kang, Hye Jeong Yang, Dae Young Kwon, Jong Ho Lee
OBJECTIVE: The objective of this study was to investigate the impact of supplementation with fermented Maillard-reactive whey protein (F-MRP) on natural killer (NK) cell activity, circulating cytokines, and serum protein levels. METHODS: A randomized, double-blind, placebo-controlled study was conducted on a sample of 80 participants without diabetes or obesity. Over an 8-week study period, the F-MRP group consumed 6 g of powder containing 4.2 g of F-MRP each day, whereas the placebo group consumed the same amount of maltodextrin...
April 19, 2017: Food & Function
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