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Thyroid FNA

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https://www.readbyqxmd.com/read/29035129/factors-influencing-the-outcome-from-ultrasonography-guided-fine-needle-aspiration-of-benign-thyroid-cysts-and-partially-cystic-thyroid-nodules-a-multicenter-study
#1
Hyun Kyung Lim, Dong Wook Kim, Jung Hwan Baek, Jung Yin Huh, Ji Hwa Ryu, Jin Yong Sung, Sung Hee Park
PURPOSE: The effect of ultrasonography (US)-guided fine-needle aspiration (US-FNA) for the collapse of benign cystic thyroid nodules is still unclear. This study aimed to assess the positive response rate following US-FNA of the cystic component of thyroid cysts and of partially cystic thyroid nodules (PCTNs), and to evaluate the factors influencing the outcome. METHODS: From June to December 2013, seven radiologists at seven institutions prospectively performed US-FNA on 320 cystic thyroid nodules in 320 patients...
October 16, 2017: Endocrine Research
https://www.readbyqxmd.com/read/29025986/-18-f-fluorodeoxyglycose-avid-thyroid-incidentalomas-the-importance-of-contextual-interpretation
#2
David A Pattison, Michael Bozin, Alexandra Gorelik, Michael S Hofman, Rodney J Hicks, Anita Skandarajah
Background: FDG-avid thyroid incidentalomas (TI) are seen in approximately 2.5% of patients imaged for staging or response assessment of malignancy and represent thyroid cancer in approximately 35% of cases. Consequently, the 2015 ATA guidelines strongly recommend investigation of all FDG-avid nodules ≥1cm with US and fine needle aspiration cytology (FNA). This study aims to assess the overall and thyroid cancer specific survival in a large cohort of patients with FDG-avid TI with long-term follow-up to assess the validity of this approach...
October 12, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29024261/pathologic-significance-of-a-novel-oncoprotein-in-thyroid-cancer-progression
#3
Anthony A Firek, Mia C Perez, Amber Gonda, Li Lei, Iqbal Munir, Alfred A Simental, Frances E Carr, Benjamin J Becerra, Marino De Leon, Salma Khan
BACKGROUND: The incidence of thyroid cancer is increasing worldwide, and there is an emerging need to develop accurate tools for diagnosis. Fine needle aspiration biopsy has greatly improved evaluation of thyroid nodules, but challenges with indeterminate lesions remain in up to 25% of biopsies. Novel tissue biomarkers may assist in improved nodule characterization. Microcalcifications occurring in thyroid cancers suggest proteins involved in bone formation may play a role in thyroid carcinogenesis...
October 11, 2017: Head & Neck
https://www.readbyqxmd.com/read/29023564/large-%C3%A2-3cm-thyroid-nodules-with-benign-cytology-can-thyroid-imaging-reporting-and-data-system-tirads-help-predict-false-negative-cytology
#4
Se Jin Nam, Jin Young Kwak, Hee Jung Moon, Jung Hyun Yoon, Eun-Kyung Kim, Ja Seung Koo
BACKGROUND: There is controversy about the accuracy of the fine-needle aspiration (FNA) cytology results in large sized thyroid nodules. Our aim was to evaluate the false-negative rate of FNA for large thyroid nodules and the usefulness of the Thyroid Imaging Reporting and Data System (TIRADS) in predicting false-negative cytology for large thyroid nodules with benign cytology. METHODS: 632 thyroid nodules larger than or equal to 3cm in size with subsequent benign cytology on US-guided FNA were included...
2017: PloS One
https://www.readbyqxmd.com/read/29022643/the-efficiency-of-elastography-in-the-diagnostics-of-follicular-lesions-and-nodules-with-an-unequivocal-fna-result
#5
Martyna Wojtaszek-Nowicka, Dorota Słowińska-Klencka, Stanisław Sporny, Bożena Popowicz, Krzysztof Kuzdak, Lech Pomorski, Krzysztof Kaczka, Jan Sopiński, Mariusz Klencki
INTRODUCTION: The aim was to assess the usefulness of strain elastography (SEG) in the diagnostics of two groups of thyroid nodules (TNs): follicular lesions (FL) with low malignancy risk (< 20.0%) and low percentage of papillary carcinomas (PTCs) among cancers as well as TNs with unequivocal cytology (UC) and high percentage of PTCs among cancers. MATERIAL AND METHODS: 168 TNs were analysed and eventually surgically treated: 100 UC (50 benign and 50 malignant - 90...
October 12, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/29017315/thyroid-cytology-the-japanese-system-and-experience-at-yamashita-thyroid-hospital
#6
Shinya Satoh, Hiroyuki Yamashita, Kennichi Kakudo
In Japan, fine needle aspiration (FNA) cytology is the most important diagnostic modalities for triaging patients with thyroid nodules. A clinician (endocrinologist, endocrine surgeon, or head and neck surgeon) generally performs FNA cytology at the outpatient clinic, and ultrasound (US)-guided FNA is widespread because US is extremely common and most clinicians are familiar with it. Although almost all FNA thyroid samples are examined by certified cytopathologists and pathologists, some clinicians assess cytological specimens themselves...
October 11, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28994276/thyroid-fine-needle-aspiration-practice-in-the-philippines
#7
Agustina D Abelardo
Fine-needle aspiration (FNA) is a well accepted initial approach in the management of thyroid lesions. It has gone a long way since its introduction for nearly a century. In the Philippines, FNA of the thyroid started 30 years ago and has been utilized until now as a mainstay in the diagnosis of thyroid malignancy. The procedure is performed by pathologists, endocrinologists, surgeons and radiologists. Majority of pathologists report the cytodiagnosis using a combination of the aspiration biopsy cytology method that closely resembles the histopathologic diagnosis of thyroid disorders and the six-tier nomenclature of The Bethesda System for Reporting Thyroid Cytopathology...
October 5, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28982301/low-malignancy-rates-in-fine-needle-aspiration-cytologies-in-a-primary-care-setting-in-germany
#8
Markus Eszlinger, Maha Ullmann, Ilka Ruschenburg, Katharina Böhme, Fabian Görke, Christiane Franzius, Sabine Adam, Thomas Molwitz, Christian Landvogt, Bassam Amro, Anja Hach, Berit Feldmann, Dieter Graf, Antje E Wefer, Rainer Niemann, Catharina Bullmann, Günther Klaushenke, Reinhard Santen, Gregor Tönshoff, Velimir Ivancevic, Andreas Kögler, Eberhard Bell, Bernd Lorenz, Gerald Kluge, Christoph Hartenstein, Ralf Paschke
BACKGROUND: Reported results for thyroid nodule fine needle aspiration (FNA) cytology mainly originate from tertiary centers. However, thyroid nodule FNA cytology is mainly performed in primary care settings for which the distribution of FNA Bethesda categories and their respective malignancy rates are largely unknown. Therefore, this study investigated FNA cytology malignancy rates of a large primary care setting to determine to what extent current evidence based strategies for the malignancy risk stratification of thyroid nodules are applied and applicable in such primary care settings...
October 6, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28979135/intraoperative-measurement-of-thyroglobulin-in-lymph-node-aspirates-for-the-detection-of-metastatic-papillary-thyroid-carcinoma
#9
Yizeng Wang, Yuanchao Liu, Xiaoning Wang, Xin Li, Ruoyu Jiang, Xianghui He
BACKGROUND: Among patients with papillary thyroid carcinoma (PTC), 30%-80% have cervical lymph node (LN) metastases, which are most commonly located in the central compartment. However, preoperative ultrasonography identifies malignant central compartment LNs in only 20%-30% of cases. We aimed to evaluate the diagnostic value of intraoperative thyroglobulin (Tg) measurement in fine-needle aspirates (FNA-Tg) of suspicious metastatic LNs. METHODS: In total, 75 patients (75 LNs) with PTC or suspected PTC were enrolled in this study...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28977955/a-meta-analysis-of-hashimoto-s-thyroiditis-and-papillary-thyroid-carcinoma-risk
#10
Xingjian Lai, Yu Xia, Bo Zhang, Jianchu Li, Yuxin Jiang
OBJECTIVE: It remains inconclusive whether Hashimoto's thyroiditis (HT) predisposes patients to the development of papillary thyroid carcinoma (PTC). We conducted a meta-analysis of the available data to address this question. RESULTS: Twenty-seven eligible studies were selected, including 18 archival thyroidectomy studies, 6 fine-needle aspiration (FNA) studies, and 3 selective FNA or thyroidectomy studies. A total of 76,281 patients, including 12,476 cases of thyroid cancer, were included in these studies...
September 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28969133/fine-needle-aspiration-of-de-quervain-s-thyroiditis-subacute-granulomatous-thyroiditis-a-cytological-review-of-20-cases
#11
Rachna Lamichaney, Mingma Sherpa, Deepak Das, Chumila Thinley Bhutia, Sabina Laishram
INTRODUCTION: De Quervain's Thyroiditis (DQT) is a self limiting inflammatory disease of the thyroid gland that presents with pain and sore throat. Although the diagnosis is usually made clinically, Fine Needle Aspiration (FNA) may provide assistance, particularly in excluding other thyroid lesions. AIM: The objective of this study was to reveal the cytological characteristics of DQT. MATERIALS AND METHODS: We retrospectively reviewed the clinical and FNAC findings of 20 cases of DQT to find the most reliable features for a confident cytological diagnosis...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28962946/mitochondrial-dna-common-deletion-in-post-fna-infarcted-oncocytic-thyroid-tumors
#12
Luca Conti, Simona Vatrano, Luca Bertero, Lavinia Masu, Donatella Pacchioni, Lorenzo Daniele, Giovanni De Rosa, Paola Cassoni, Marco Volante, Mauro Papotti
Thyroid fine needle aspiration (FNA) can rarely induce morphological changes potentially hindering the histopathological diagnosis, especially in Hurthle cell tumors (HCT), which may easily undergo post-FNA infarction or necrosis. HCTs contain mitochondrion (mt)-rich cells that may bear mtDNA mutations, the most frequent being the so-called "common deletion" (CD). The aim of this study was to determine the presence and extent of the mtDNA CD in a series of thyroid HCT that underwent extensive infarction following FNA procedure, in comparison with a control series of HCT lacking post-FNA ischemic/hemorrhagic alterations...
September 26, 2017: Human Pathology
https://www.readbyqxmd.com/read/28949443/value-of-cytopathologist-review-of-ultrasound-examinations-in-non-diagnostic-unsatisfactory-thyroid-fna
#13
David N Poller
BACKGROUND: Correlation of cytologic and ultrasound findings is extremely valuable for the cytopathologist in management of thyroid nodules. METHODS: Ultrasound scans (US) of all thyroid FNA taken over a 13 month period and reported by a single cytologist were reviewed at the time of reporting, focusing on aspirates that were non-diagnostic/unsatisfactory, equivalent to Bethesda Class I, UK Royal College of Pathologists Class Thy1 or Thy1c. RESULTS: FNA cases [68 (40...
September 26, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28937915/mir-146b-measurement-in-fna-to-distinguish-papillary-thyroid-cancer-from-benign-thyroid-masses
#14
F Yang, H Zhang, X Leng, F Hao, L Wang
No abstract text is available yet for this article.
September 22, 2017: British Journal of Biomedical Science
https://www.readbyqxmd.com/read/28927353/recurrent-metastatic-medullary-thyroid-carcinoma-a-case-of-sustained-response-to-prolonged-treatment-with-somatostatin-analogues
#15
Juana María Cano, Rocío Galán, Rafael López
BACKGROUND: Medullary thyroid carcinoma (MTC) is a rare disease. Treatment options for recurrent disease are limited. Somatostatin analogues might have a role as anticancer agents agents in MTC, although the evidence is inconclusive. PATIENT FINDINGS: A 64-year old male was diagnosed with MTC in January 2010. Total thyroidectomy with neck dissection (stage IVA, pT2pN1bM0, R1) was performed, followed by adjuvant locoregional radiotherapy. Two years later, the patient developed recurrent metastatic disease evidenced by elevated carcinoembryonic antigen (CEA) and calcitonin levels, and a positive uptake (Octreoscan®) in the right adrenal gland and pancreatic head...
September 19, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28926837/vascular-proliferation-associated-with-florid-granulomatous-reaction-after-fna-in-a-benign-thyroid-nodule
#16
José Cândido Caldeira Xavier-Júnior, Deolino João Camilo-Júnior, Solange Correa Garcia Pires D'ávilla, Neivio José Mattar
No abstract text is available yet for this article.
September 20, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28925594/pharyngoesophageal-diverticula-simulating-thyroid-nodules-an-unusual-occurrence-with-unique-features
#17
Karen K Nauschuetz, Lorna L Ogden, Cherry E Starling, Mohammad J Saleh, Allan C Golding, S Thomas Traweek
Pharyngoesophageal diverticula (PED) of the Zenker's and Killian-Jamieson types arise in close proximity to the thyroid gland, and may rarely be confused with a thyroid nodule on ultrasonography. In this brief report, we detail the cytologic, clinical, and radiologic findings of three PED that were thought to be thyroid nodules, and were subjected to fine-needle aspiration (FNA). The patients were females with an age range of 51-64 years. All three patients had multiple thyroid nodules, and two patients reported symptoms attributable to the diverticulum...
September 19, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28920749/american-association-of-clinical-endocrinologists-and-american-college-of-endocrinology-disease-state-commentary-managing-thyroid-tumors-diagnosed-as-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features
#18
Zubair W Baloch, R Mack Harrell, Elise M Brett, Gregory Randolph, Jeffrey R Garber
This commentary summarizes the history and reclassification of noninvasive follicular thyroid neoplasm with papillary-like nuclei (NIFTP). It reviews the salient histopathologic features that are based on immunohistochemical and molecular profiles and serve as inclusion and exclusion criteria. The authors also provide their own point of view regarding the practical issues and possible concerns that may be raised by both clinicians and patients based on the diagnosis of NIFTP. ABBREVIATIONS: AACE = American Association of Clinical Endocrinologists EFVPTC = encapsulated FVPTC FNA = fine-needle aspiration FVPTC = follicular variant of papillary thyroid carcinoma NIFTP = noninvasive follicular thyroid neoplasm with papillary-like nuclear features PTC = papillary thyroid carcinoma...
September 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28914983/suggesting-the-cytologic-diagnosis-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-niftp-a-retrospective-analysis-of-atypical-and-suspicious-nodules
#19
Kyle C Strickland, Brooke E Howitt, Justine A Barletta, Edmund S Cibas, Jeffrey F Krane
BACKGROUND: The term "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) has replaced a subset of follicular variant of papillary thyroid carcinoma due to the indolent behavior of such tumors. NIFTPs are most often classified in an "indeterminate" diagnostic category. In the current study, the authors sought to identify cytologic features helpful in distinguishing NIFTP from other entities in these categories, particularly benign nodules. METHODS: The authors retrospectively evaluated a consecutive cohort of 130 thyroid fine-needle aspiration (FNA) specimens with an indeterminate diagnosis and available histopathologic follow-up...
September 15, 2017: Cancer
https://www.readbyqxmd.com/read/28914044/how-many-patients-with-tir3-fna-really-have-a-thyroid-neoplasm
#20
Angela Pezzolla, Serafina Lattarulo, Andrea Madaro, Giovanni Docimo, Emanuela Lacalendola, Francesco Prete, Rinaldo Marzaioli
No abstract text is available yet for this article.
December 2017: Minerva Endocrinologica
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