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Thyroid cytopathology

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https://www.readbyqxmd.com/read/27900100/avoidance-of-unnecessary-fine-needle-aspiration-with-the-use-of-the-thyroid-imaging-reporting-data-system-classification-and-strain-elastography-based-on-the-bethesda-system-for-reporting-thyroid-cytopathology
#1
Murat Erkan, Sule Canberk, Gamze Z Kilicoglu, Mine Onenerk, Atay Uludokumaci, Pembegul Gunes, Tugba Atasoy
Thyroid fine-needle aspiration (FNA) biopsy has been widely accepted as an accurate and cost-effective tool in the management of thyroid nodules. To avoid unnecessary FNAs and provide appropriate management, patient evaluation should be based on a multidisciplinary approach. For this purpose, the Thyroid Imaging Reporting and Data System (TI-RADS) and strain elastography (SE) were proposed as tools for the risk assessment of malignancy in thyroid nodules. The aim of the present study was to analyze the utility of TI-RADS system and SE, along with FNA, and prospectively evaluate 369 consecutive patients referred for FNA of a thyroid nodule...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27845971/the-follicular-variant-of-papillary-thyroid-cancer-and-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-niftp
#2
Joseph Scharpf, Dipti Kamani, Peter M Sadow, Gregory W Randolph
PURPOSE OF REVIEW: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a new terminology proposed for encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC). Recently, thyroid cancer incidence has increased dramatically, without affecting related mortality rate. This increase is widely attributed to the intensified surveillance leading to a substantial increase in the diagnosis of small classic papillary thyroid cancers and EFVPTCs...
January 2017: Current Opinion in Oncology
https://www.readbyqxmd.com/read/27805843/diagnosis-and-management-of-small-thyroid-nodules-a-comparative-study-with-six-guidelines-for-thyroid-nodules
#3
Jung Hyun Yoon, Kyunghwa Han, Eun-Kyung Kim, Hee Jung Moon, Jin Young Kwak
Purpose To investigate the diagnostic performances of six guidelines used to assess thyroid nodules and to determine whether any of these guidelines identify cancers of aggressive form in this population. Materials and Methods From March 2007 to February 2010, 4696 thyroid nodules that were 1-2 cm in 4585 patients were diagnosed as benign or malignant on the basis of cytopathologic results. Ultrasonographic examinations of the thyroid nodules were retrospectively reviewed and categorized according to the categories defined by six previously published guidelines for thyroid nodules...
November 2, 2016: Radiology
https://www.readbyqxmd.com/read/27789025/can-thyroid-surgery-be-decided-based-on-ultrasonographic-findings-irrespective-of-cytopathological-findings-five-year-retrospective-study-in-a-district-general-hospital
#4
A A Elsayed, C Murdoch, S Murray, K Bashir
AIM: To evaluate whether thyroid surgery be decided based on ultrasonographic criteria of the nodule(s), irrespective of cytopathological findings. MATERIALS AND METHODS: The histopathological findings of resected thyroid lobes were retrospectively reviewed and the findings were compared with the preoperative ultrasonographic and cytopathological findings. RESULTS: The results suggest that the decision to operate on thyroid lesions based on suspicious sonographic findings was correct in a significant number of patients irrespective of the preoperative cytopathological findings...
October 24, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27788511/the-bethesda-system-for-reporting-thyroid-cytopathology-ii
#5
Syed Z Ali, Edmund S Cibas
No abstract text is available yet for this article.
2016: Acta Cytologica
https://www.readbyqxmd.com/read/27764825/the-bethesda-system-for-reporting-thyroid-cytopathology-proposed-modifications-and-updates-for-the-second-edition-from-an-international-panel
#6
Marc Pusztaszeri, Esther Diana Rossi, Manon Auger, Zubair Baloch, Justin Bishop, Massimo Bongiovanni, Ashish Chandra, Beatrix Cochand-Priollet, Guido Fadda, Mitsuyoshi Hirokawa, SoonWon Hong, Kennichi Kakudo, Jeffrey F Krane, Ritu Nayar, Sareh Parangi, Fernando Schmitt, William C Faquin
The Bethesda System for Reporting Thyroid Cytology (TBSRTC) was proposed in 2007 at the National Cancer Institute Thyroid Fine Needle Aspiration State of the Art and Science Conference held in Bethesda, Maryland. The aim was to address the inconsistent and sometimes confusing reporting terminologies used for thyroid FNA throughout the world. The TBSRTC consists of 6 diagnostic categories, each associated with an implied risk of malignancy that translates directly into a clinical management algorithm. Since the publication of the TBSRTC cytology Atlas in January 2010, considerable experience has been gained regarding its application in cytology practice, clinical impact, and limitations...
2016: Acta Cytologica
https://www.readbyqxmd.com/read/27761885/diagnostic-assessment-of-intraoperative-cytology-for-papillary-thyroid-carcinoma-using-a-decision-tree-analysis
#7
J-S Pyo, J H Sohn, G Kang
PURPOSE: The aim of this study was to elucidate the cytological characteristics and the diagnostic usefulness of intraoperative cytology (IOC) for papillary thyroid carcinoma (PTC). In addition, using decision tree analysis, effective features for accurate cytological diagnosis were sought. METHODS: We investigated cellularity, cytological features and diagnosis based on the Bethesda System for Reporting Thyroid Cytopathology in IOC of 240 conventional PTCs. The cytological features were evaluated in terms of nuclear score with nuclear features, and additional figures such as presence of swirling sheets, psammoma bodies, and multinucleated giant cells...
October 19, 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27684984/application-of-the-bethesda-classification-for-thyroid-fine-needle-aspiration-institutional-experience-and-meta-analysis
#8
Elliot A Krauss, Megan Mahon, Jean M Fede, Lanjing Zhang
CONTEXT: -Fine-needle aspiration (FNA) biopsies have been an important component in the preoperative evaluation of thyroid nodules. Until the introduction of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) in 2008, individual institutions had developed their own diagnostic categories. The BSRTC proposed 6 categories in an attempt to standardize reporting of thyroid FNA. OBJECTIVE: -To present a 15-year experience of thyroid FNA at one institution, including data before and after introduction of the BSRTC...
October 2016: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27666595/bethesda-classification-is-a-valuable-guide-for-fine-needle-aspiration-reports-and-highly-predictive-especially-for-diagnosing-aggressive-variants-of-papillary-thyroid-carcinoma
#9
B Evranos, S B Polat, H Baser, D Ozdemir, A Kilicarslan, A Yalcin, R Ersoy, B Cakir
BACKGROUND: A fine needle aspiration biopsy (FNAB) is the most valuable diagnostic procedure for pre-operative discrimination of benign and malignant nodules. The Bethesda System for Reporting Thyroid Cytopathology provides standardised reporting and cytomorphological criteria in aspiration smears. The aim of the present study was to determine malignancy rates in nodules with different cytology results and evaluate the diagnostic value of Bethesda for variants of papillary thyroid carcinoma (PTC)...
September 25, 2016: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/27664888/frozen-section-analysis-in-the-post-bethesda-era
#10
Travis M Cotton, Jing Xin, John Sandyhya, Roy Lirov, Barbara S Miller, Mark S Cohen, Paul G Gauger, David T Hughes
BACKGROUND: The utility of frozen section (FS) for indeterminate thyroid nodules is controversial. In 2009, the Bethesda System for Reporting Thyroid Cytopathology was established to further subcategorize indeterminate fine-needle aspiration results (follicular lesions, FL) into Bethesda category 3 (BC3) and Bethesda category 4 (BC4). We hypothesize that FS will have less utility in the evaluation of BC3 lesions when compared to BC4. MATERIALS AND METHODS: A total of 479 patients who underwent thyroid lobectomy from January 2008 to July 2014 were retrospectively reviewed...
October 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27643719/carcinoma-showing-thymus-like-differentiation-castle-cytopathological-features-and-differential-diagnosis
#11
Jennifer A Collins, Bo Ping, Justin A Bishop, Syed Z Ali
BACKGROUND: CASTLE (carcinoma showing thymus-like differentiation) is a rare tumor (accounting for less than 0.15% of thyroid neoplasms) with most of the reported cases from Asia. Although this tumor is rare, distinguishing it from more aggressive neoplasms is critical because of its improved prognosis. To date, there have been limited studies on its cytomorphological features. Herein, we review the cytomorphological features of 10 fine-needle aspiration (FNA) cases of histologically confirmed CASTLE and discuss the findings in light of the current literature...
2016: Acta Cytologica
https://www.readbyqxmd.com/read/27633961/mammary-analog-secretory-carcinoma-of-thyroid-a-case-report
#12
Aaron P Rupp, Thèrése J Bocklage
Mammary analog secretory carcinoma (MASC) is a recently described rare neoplasm that was first reported in the salivary gland with an associated ETV6-NTRK3 fusion. We present a case of MASC involving and presumably arising in the thyroid, which was originally diagnosed as papillary thyroid carcinoma on fine needle aspiration and surgical resection. The later correct diagnosis of MASC was confirmed by immunohistochemistry and molecular studies. The cytopathological features of MASC in the salivary gland are previously described; however, we present the first cytopathological description of MASC arising in the thyroid with the unique feature of prominent nuclear grooves...
September 15, 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27629534/using-computerized-cytomorphometry-to-distinguish-between-benign-and-malignant-cases-in-thyroid-fine-needle-aspiration-cytology
#13
Zeliha Esin Celik, Serdar Altinay, Fahriye Kilinc, Nur Arslan, Burcu Sanal Yilmaz, Pınar Karabagli, Ceyhan Ugurluoglu
BACKGROUND: Only a small number of studies on computerized cytomorphometry have been performed for thyroid FNAC. The present study aimed to determine the usefulness of computerized cytomorphometry methods to further classify thyroid lesions as benign or malignant and to compare the practicability and value of using Papanicolaou (Pap) and Giemsa stains in thyroid FNAC by evaluating their association to various cytologic nuclear parameters. METHODS: Fifty-eight thyroid lesions diagnosed by FNAC and categorized according to the Bethesda system for reporting thyroid cytopathology were evaluated in terms of various cytologic nuclear parameters, including nuclear area (NA), nuclear perimeter (NP), nuclear density (ND), long nuclear diameter (LND), and short nuclear diameter (SND)...
November 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27627674/a-different-perspective-on-evaluating-the-malignancy-rate-of-the-non-diagnostic-category-of-the-bethesda-system-for-reporting-thyroid-cytopathology-a-single-institute-experience-and-review-of-the-literature
#14
Pembegul Gunes, Sule Canberk, Mine Onenerk, Murat Erkan, Nilufer Gursan, Emine Kilinc, Gamze Zeynep Kilicoglu
OBJECTIVE: To determine the malignancy rate in the non-diagnostic (ND) category of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) based on a different approach in relation to histopathology diagnoses. STUDY DESIGN: All ND fine needle aspirations (FNAs) that were performed under ultrasound guidance by an interventional radiologist with rapid on-site evaluation were included in the study. Slides were reevaluated to identify the cause of inadequacy as "qualitative" or "quantitative...
2016: PloS One
https://www.readbyqxmd.com/read/27623969/proposal-for-a-novel-management-of-indeterminate-thyroid-nodules-on-the-basis-of-cytopathological-subclasses
#15
Martina Rossi, Sabrina Lupo, Roberta Rossi, Paola Franceschetti, Giorgio Trasforini, Stefania Bruni, Federico Tagliati, Mattia Buratto, Giovanni Lanza, Luca Damiani, Ettore Degli Uberti, Maria Chiara Zatelli
Indeterminate thyroid nodules include heterogeneous lesions that could benefit from a differential management. Our aim is to better define the management of the Bethesda System for Reporting Thyroid Cytopathology class III and IV nodules, by identifying cytological subcategories among Bethesda System for Reporting Thyroid Cytopathology class III associated with different clinical risk, by means of ultrasound, repeated FNAB, and BRAFV600E molecular analysis. We also evaluated the outcome of nodules not operated, over a 5-year follow-up...
September 13, 2016: Endocrine
https://www.readbyqxmd.com/read/27617626/current-status-and-diagnostic-values-of-the-bethesda-system-for-reporting-thyroid-cytopathology-in-a-papillary-thyroid-carcinoma-prevalent-area
#16
You-Bin Lee, Yoon Young Cho, Ju Young Jang, Tae Hyuk Kim, Hye Won Jang, Jae Hoon Chung, Young Lyun Oh, Sun Wook Kim
BACKGROUND: Most studies validating the Bethesda system for reporting thyroid cytopathology (TBSRTC) have been conducted in Western countries. We explored the current status of TBSRTC in an area where most thyroid malignancies are papillary carcinomas. METHODS: Fine-needle aspirations (FNAs) of thyroid nodules performed in 2013 were retrospectively analyzed and the results were compared to final pathology on resection. RESULTS: Of 1947 FNAs, 1925 (98...
September 12, 2016: Head & Neck
https://www.readbyqxmd.com/read/27594994/comparison-of-1869-thyroid-ultrasound-guided-fine-needle-aspiration-biopsies-between-general-surgeons-and-interventional-radiologists
#17
Hilmi Bozkurt, Oktay İrkörücü, Mehmet Aziret, Enver Reyhan, Mehmet Kemal Okuyan
BACKGROUND: Thyroid nodules are commonly encountered problems in clinical practice. For patients who have a thyroid nodule, the fine-needle aspiration biopsy (FNAB) is the most important test, as it is the most reliable diagnostic method for distinguishing between benign thyroid nodules and cancerous nodules. FNAB is able to be performed either via an ultrasound (USG) or alone and is the first choice when it comes to diagnosing thyroid nodules, given that it is cheap, safe and provides accurate results...
September 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27543982/fine-needle-aspiration-cytology-of-noninvasive-follicular-variant-of-papillary-thyroid-carcinoma-is-cytomorphologically-distinct-from-the-invasive-counterpart
#18
Ashley A Ibrahim, Howard H Wu
OBJECTIVES: To review a series of noninvasive encapsulated follicular variant of papillary thyroid carcinomas (FVPTCs) in an attempt to further define the role of cytopathology in the diagnosis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features and invasive FVPTC. METHODS: Surgical pathology cases diagnosed as FVPTC with correlating thyroid fine-needle aspiration (FNA) were identified and divided into two FVPTC groups: noninvasive and invasive...
September 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/27513265/the-incidence-of-18f-fdg-pet-ct-thyroid-incidentalomas-andthe-prevalence-of-malignancy-a-prospective-study
#19
Mine Şencan Eren, Özhan Özdoğan, Arzu Gedik, Mehmet Ceylan, Merih Güray Durak, Mustafa Seçil, Mehmet Ali Koçdor, Abdurrahman Çömlekçi, Hatice Durak
BACKGROUND/AIM: To determine the prevalence of malignancy in thyroid incidentalomas (TIs) detected by fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). MATERIALS AND METHODS: 18F-FDG PET/CT images were evaluated prospectively for the presence of thyroid uptake. The patients with a TI were evaluated by an endocrinologist according to the predefined diagnostic algorithm. The final diagnosis was obtained clinically and/or by pathology...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27465606/diagnosis-and-surgical-indications-of-oxyphilic-follicular-tumors-in-japan-surgical-specimens-and-cytology
#20
Yasuhiro Ito, Mitsuyoshi Hirokawa, Akira Miyauchi, Minoru Kihara, Tomonori Yabuta, Hiroo Masuoka, Mitsuhiro Fukushima, Takuya Higashiyama, Kaoru Kobayashi, Akihiro Miya
Oxyphilic cell carcinoma is a relatively rare type of differentiated thyroid carcinoma. We investigated the diagnosis of oxyphilic cell carcinoma based on surgical specimens and cytology to elucidate the indications for surgery for oxyphilic tumors. Among 330 patients pathologically diagnosed as having an oxyphilic cell carcinoma or adenoma, the incidence of carcinoma was 21%. The pathological diagnosis of oxyphilic cell carcinoma was related to tumor size (>4 cm). On cytology, 79% of the tumors were classified as category IV or greater by the Bethesda System for Reporting Thyroid Cytopathology (BSRTC), but no significant difference was established between category IV or greater and categories I-III regarding the incidence of carcinoma...
November 30, 2016: Endocrine Journal
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