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https://www.readbyqxmd.com/read/28535481/graphene-oxide-enzyme-hybrid-nanoflowers-for-efficient-water-soluble-dye-removal
#1
Hui Li, Jingwei Hou, Linlin Duan, Chao Ji, Yatao Zhang, Vicki Chen
High efficient enzyme immobilization on carbon based conductive supports could provide wide applications in energy and environmental science. Here, we synthesized a 3D flower-like structured self-assembly hybrid nanocomposite with copper phosphate, laccase, graphite oxide (GO) and carbon nanotubes (CNTs) via a facile one-pot strategy under mild conditions. The prepared nanocomposite exhibited very high enzyme loading and improved laccase activity. During the formation of the nanocomposite, the copper phosphate-laccase petals were interwined by CNTs, and GO nanosheets were further coated on the petal surface...
May 11, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28535116/is-mannitol-the-treatment-of-choice-for-patients-with-ciguatera-fish-poisoning
#2
Michael E Mullins, Robert S Hoffman
CONTEXT: Ciguatera fish poisoning arises primarily from consumption of carnivorous reef fish caught in tropical and sub-tropical waters. Ciguatoxins, a class of tasteless, heat-stable, polycyclic toxins produced by dinoflagellates, accumulate through the food chain and concentrate in various carnivorous fish, such as groupers, barracudas, wrasses, amberjack, kingfishes, and eels. Characteristics of ciguatera fish poisoning include early nausea, vomiting, and diarrhea in the first one to two days post ingestion, followed by the appearance of sensory disturbances...
May 23, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28534676/applications-of-raman-spectroscopy-in-biopharmaceutical-manufacturing-a-short-review
#3
Kevin Buckley, Alan G Ryder
The production of active pharmaceutical ingredients (APIs) is currently undergoing its biggest transformation in a century. The changes are based on the rapid and dramatic introduction of protein- and macromolecule-based drugs (collectively known as biopharmaceuticals) and can be traced back to the huge investment in biomedical science (in particular in genomics and proteomics) that has been ongoing since the 1970s. Biopharmaceuticals (or biologics) are manufactured using biological-expression systems (such as mammalian, bacterial, insect cells, etc...
June 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28530538/qualitative-estimation-of-drug-entrapment-efficiency-in-polymeric-nano-micelles-using-dpd
#4
Farzin Hadizadeh, Jamal Shamsara
BACKGROUND: Dissipative particle dynamics (DPD) is a simulation method that one of its applications is in the field of pharmaceutical science and drug delivery. OBJECTIVE: DPD is employed to study morphology and some other characteristics of polymeric nano-micelles. Two systems were considered in this study: system A which includes curcumin, Polycaprolactone (PCL), Polyethylene glycol (PEG) and water beads and system B which includes paclitaxel, Polylactic acid (PLA), PEG and water beads...
May 22, 2017: Pharmaceutical Nanotechnology
https://www.readbyqxmd.com/read/28526694/measuring-osmosis-and-hemolysis-of-red-blood-cells
#5
Lauren K Goodhead, Frances M MacMillan
Since the discovery of the composition and structure of the mammalian cell membrane, biologists have had a clearer understanding of how substances enter and exit the cell's interior. The selectively permeable nature of the cell membrane allows the movement of some solutes and prevents the movement of others. This has important consequences for cell volume and the integrity of the cell and, as a result, is of utmost clinical importance, for example in the administration of isotonic intravenous infusions. The concepts of osmolarity and tonicity are often confused by students as impermeant isosmotic solutes such as NaCl are also isotonic; however, isosmotic solutes such as urea are actually hypotonic due to the permeant nature of the membrane...
June 1, 2017: Advances in Physiology Education
https://www.readbyqxmd.com/read/28525935/design-synthesis-and-characterization-of-doped-titanium-oxide-nanomaterials-with-environmental-and-angiogenic-applications
#6
Susheel Kumar Nethi, Neeraja Aparna Anand P, Beatriz Rico-Oller, Antonio Rodríguez-Diéguez, Santiago Gómez-Ruiz, Chitta Ranjan Patra
Since the last decade, the metal composite nanostructures have evolved as promising candidates in regard to their wide applications in the fields of science and engineering. Recently, several investigators identified the titanium based nanomaterials as excellent agents for multifunctional environmental and biomedical applications. In this perspective, we have developed a series of zinc-doped (2 and 5%) titanium oxide-based nanomaterials using various reaction conditions and calcination temperatures (TZ1-TZ3: calcined at 500°C, TZ4-TZ6: calcined at 600°C and TZ7-TZ9: calcined at 700°C)...
May 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28523825/biphasic-supramolecular-self-assembly-of-ferric-ions-and-tannic-acid-across-interfaces-for-nanofilm-formation
#7
Beom Jin Kim, Sol Han, Kyung-Bok Lee, Insung S Choi
Cell nanoencapsulation provides a chemical tool for the isolation and protection of living cells from harmful, and often lethal, external environments. Although several strategies are available to form nanometric films, most methods heavily rely on time-consuming multistep processes and are not biocompatible. Here, the interfacial supramolecular self-assembly and film formation of ferric ions (Fe(III) ) and tannic acid (TA) in biphasic systems is reported, where Fe(III) and TA come into contact each other and self-assemble across the interface of two immiscible phases...
May 19, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28520802/aquatic-cycling-what-do-we-know-a-scoping-review-on-head-out-aquatic-cycling
#8
Stefanie Rewald, Ilse Mesters, Antoine F Lenssen, Jens Bansi, Johan Lambeck, Rob A de Bie, Benjamin Waller
Over the past few years, aquatic cycling has become a trending fitness activity. However, the literature has not been reviewed exhaustively. Therefore, using scoping review methodology, the aim of this review was to explore the current state of the literature concerning aquatic cycling. This study specifically focused on study designs, populations and outcomes. A comprehensive search of seven databases (PubMed, MEDLINE, Cinahl, Embase, PEDro,Web of Science, WorldCat) was conducted up to 30th September 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28518407/nad-a-big-player-in-cardiac-and-skeletal-muscle-remodeling-and-aging
#9
REVIEW
Pankaj Chaturvedi, Suresh C Tyagi
In the past decade, NAD+ has gained importance for its beneficial effects as antioxidant and antiaging molecule. A paper in science by Zhang et al (2016) has described that NAD+ when replenished, ameliorates muscle dystrophy in mice by improving mitochondrial function. NAD+ was also demonstrated by the authors to improve the life span of mice. Cox et al (2002) demonstrated the cardiac effects of NAD+ which mitigated chronic heart failure via mitochondrial redox state mechanism. Cox et al (2002) also demonstrated that NAD+ is provided in the drinking water, it improves cardiac relaxation in volume overload model of heart failure...
May 18, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28518189/structure-and-dynamics-of-water-confined-in-a-graphene-nanochannel-under-gigapascal-high-pressure-dependence-of-friction-on-pressure-and-confinement
#10
Lei Yang, Yanjie Guo, Dongfeng Diao
Recently, water flow confined in nanochannels has become an interesting topic due to its unique properties and potential applications in nanofluidic devices. The trapped water is predicted to experience high pressure in the gigapascal regime. Theoretical and experimental studies have reported various novel structures of the confined water under high pressure. However, the role of this high pressure on the dynamic properties of water has not been elucidated to date. In the present study, the structure evolution and interfacial friction behavior of water constrained in a graphene nanochannel were investigated via molecular dynamics simulations...
May 18, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28516796/legionella-spp-in-dental-unit-waterlines
#11
E Sedlata Juraskova, H Sedlackova, J Janska, O Holy, I Lalova, I Matouskova
OBJECTIVE: To determine the current presence of Legionella spp. in the output water of dental unit waterlines (DUWLs) and examine its mitigation by disinfection at the Institute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc. MATERIAL AND METHODS: The first stage of our survey involved collecting samples of DUWL output water from 50 dental chair units (DCUs), and 2 samples of the incoming potable water...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28516359/evolution-of-choice-of-solubility-and-dissolution-media-after-two-decades-of-biopharmaceutical-classification-system
#12
Nadia Bou-Chacra, Katherine Jasmine Curo Melo, Ivan Andrés Cordova Morales, Erika S Stippler, Filippos Kesisoglou, Mehran Yazdanian, Raimar Löbenberg
The introduction of the biopharmaceutics drug classification system (Biopharmaceutics Classification System (BCS)), in 1995, provided a simple way to describe the biopharmaceutics behavior of a drug. Solubility and permeability are among the major parameters, which determine the fraction dose absorbed of a drug substance and consequently its chances to be bioavailable. The purpose of this review is to summarize the evolution of the media used for determining solubility and dissolution and how this can be used in modern drug development...
May 17, 2017: AAPS Journal
https://www.readbyqxmd.com/read/28512146/science-signaling-podcast-for-16-may-2017-vibrio-rewires-host-cells
#13
Nicole J De Nisco, Kim Orth, Annalisa M VanHook
This Podcast features a conversation with Kim Orth and Nicole De Nisco, authors of a Research Resource that appears in the 16 May 2017 issue of Science Signaling, about how the marine bacterium Vibrio parahaemolyticus rewires host cell signaling networks. V. parahaemolyticus thrives in warm brackish waters and infects both shellfish and finfish. This bacterium causes gastroenteritis when humans consume contaminated seafood that is raw or undercooked. V. parahaemolyticus delivers virulence factors into host cells through two different type 3 secretion systems (T3SSes)...
May 16, 2017: Science Signaling
https://www.readbyqxmd.com/read/28511509/comparative-evaluation-of-colour-stability-and-surface-hardness-of-methacrylate-based-flowable-and-packable-composite-in-vitro-study
#14
Saron Ramesh Nair, Nandini Thipannanavar Niranjan, Arun Jayasheel, Deepak Bythnal Suryakanth
INTRODUCTION: With the advent of new technology in material sciences in recent years, the quality of composite resin restorations has improved; however, discolouration and wear of composite resin materials remains to be a major problem in long-term clinical studies. AIM: The aim of the present study was to compare the colour stability and surface hardness of methacrylate based flowable nano composite with methacrylate based packable nano composite. MATERIALS AND METHODS: The difference in colour stability and microhardness of the three composites: G aenial Universal Flo (GC India), Filtek Z350XT (3MESPE) and Tetric N Ceram (Ivoclar Vivadent) were evaluated...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28509531/hierarchical-porous-structured-sio2-sno2-nanofibrous-membrane-with-superb-flexibility-for-molecular-filtration
#15
Haoru Shan, Xueqin Wang, Feihao Shi, Jianhua Yan, Jianyong Yu, Bin Ding
The separation and purification of chemical molecules from organic media under harsh chemical environments are of vital importance in the fields of water treatment, biomedical engineering, and organic recycling. Herein, we report the preparation of a flexible SiO2/SnO2 nanofibrous membrane (SiO2/SnO2 NFM) with high surface area and hierarchical porous structure by selecting poly(vinyl butyral) as pore-forming agent and embedding crystalline phase into amorphous matrix without using surfactant as sacrificial template...
May 23, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28508441/synthesis-of-an-aluminum-hydroxide-octamer-through-a-simple-dissolution-method
#16
Cory K Perkins, Eric S Eitrheim, Brantly L Fulton, Lauren B Fullmer, Christopher A Colla, Deok-Hie Park, Anna F Oliveri, James E Hutchison, May Nyman, William H Casey, Tori Z Forbes, Darren W Johnson, Douglas A Keszler
Multimeric oxo-hydroxo Al clusters function as models for common mineral structures and reactions. Cluster research, however, is often slowed by a lack of methods to prepare clusters in pure form and in large amounts. Herein, we report a facile synthesis of the little known cluster Al8 (OH)14 (H2 O)18 (SO4 )5 (Al8 ) through a simple dissolution method. We confirm its structure by single-crystal X-ray diffraction and show by (27) Al NMR spectroscopy, electrospray-ionization mass spectrometry, and small- and wide-angle X-ray scattering that it also exists in solution...
May 16, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28505718/mechanics-of-a-granular-skin
#17
Somnath Karmakar, Anit Sane, S Bhattacharya, Shankar Ghosh
Magic sand, a hydrophobic toy granular material, is widely used in popular science instructions because of its nonintuitive mechanical properties. A detailed study of the failure of an underwater column of magic sand shows that these properties can be traced to a single phenomenon: the system self-generates a cohesive skin that encapsulates the material inside. The skin, consisting of pinned air-water-grain interfaces, shows multiscale mechanical properties: they range from contact-line dynamics in the intragrain roughness scale, to plastic flow at the grain scale, all the way to sample-scale mechanical responses...
April 2017: Physical Review. E
https://www.readbyqxmd.com/read/28505456/self-polymerization-of-dopamine-in-acidic-environments-without-oxygen
#18
Tung-Po Chen, Tianchi Liu, Tsan-Liang Su, Jun-Feng Liang
An alkaline environment and the presence of oxygen are essential requirements for dopamine polymerization. In this study, we are the first to demonstrate the self-polymerization of dopamine through plasma-activated water (PAW) under acidic environments (pH<5.5). Resulting poly(dopamine) (PDA) were characterized using Nanosizer, SEM, FTIR, UV-vis, and fluorescence spectrophotometers and proved to have similar physical and chemical properties to those polymerized under a basic condition except that the PDA particles formed in PAW were more stable and hardly aggregated at varied pHs...
May 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28505412/diffraction-free-bloch-surface-waves
#19
Ruxue Wang, Yong Wang, Douguo Zhang, Guangyuan Si, Liangfu Zhu, Luping Du, Shanshan Kou, Ramachandram Badugu, Mary Rosenfeld, Jiao Lin, Pei Wang, Hai Ming, Xiaocong Larry Yuan, Joseph R Lakowicz
In this article, we demonstrate a diffraction-free Bloch surface wave sustained on all-dielectric multilayers that does not diffract after being passed through three obstacles or across a single mode fiber. It can propagate in a straight line for distances longer than 110 μm at a wavelength of 633 nm and could be applied as an in-plane optical virtual probe, both in air and in an aqueous environment. The ability to be used in water, its long diffraction-free distance, and its tolerance to multiple obstacles make this wave ideal for certain applications in areas such as the biological sciences, where many measurements are made on glass surfaces or for which an aqueous environment is required, and for high-speed interconnections between chips, where low loss is necessary...
May 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/28505393/the-science-behind-one-health-at-the-interface-of-humans-animals-and-the-environment
#20
Michael P Murtaugh, Clifford J Steer, Srinand Sreevatsan, Ned Patterson, Shaun Kennedy, P Sriramarao
Humans face a grand quality-of-life challenge as growing demands for resources for an ever-expanding population threaten the existence of wildlife populations, degrade land, and pollute air and water. Public investment and policy decisions that will shape future interactions of humans, animals, and the environment need scientific input to help find common ground for durable and sustainable success. The Second International Conference on One Medicine One Science brought together a broad range of scientists, trainees, regulatory authorities, and health experts from 34 countries to inform and discuss the human impacts of air quality; the complexities of water quality, access, and conflicts; the opportunities and uncertainties in precision medicine; and the role of science communication in health policy formulation...
May 2017: Annals of the New York Academy of Sciences
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