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Abdulrahman Darraj, Walid Barakat, Mona Kenani, Reem Shajry, Abdullah Khawaji, Sultan Bakri, Abdulrahman Makin, Azza Mohanna, Abu Obaida Yassin
BACKGROUND: The rise in childhood eye diseases has become a matter of concern in Saudi Arabia, and hence a study has been conducted on the residents of Jazan. The aim of the research was to find out the root cause of such issues and provide a solution to prevent such circumstances for it may affect the vision of children. In this study, therefore, we aimed to determine the types of childhood eye diseases in Jazan and to discuss the best ways to prevent them or prevent their effect on the vision of our children...
2016: Ophthalmology and Eye Diseases
Bin Zhou, Ernst Pöppel, Lingyan Wang, Taoxi Yang, Yuliya Zaytseva, Yan Bao
UNLABELLED: Single cases may lead to unexpected hypotheses in psychology. We retrospectively analyzed single case studies that suggested organizational principles along the early visual pathway, which have remained unanswered until now. FIRST CASE: In spite of the inhomogeneity of sensitivity, paradoxically the visual field on the subjective level appears to be homogeneous; constancy of brightness of supra-threshold stimuli throughout the visual field is claimed to be responsible for homogeneity; specific summation properties of retinal ganglion cells are hypothesized to guarantee this effect...
September 2016: PsyCh Journal
Muhammad Ummear Raza, Waheed Ullah, Sajid Malik
Congenital constriction ring (CCR) and symbrachydactyly are two distinct, rare, and heterogeneous limb deficiency conditions which affect the digits. Here, we report on two different individuals with an unusual presentation of limb deficiency accompanying intellectual disability (ID) and certain other malformations. In the first index female, CCR occurred with mild ID, squint eyes, obesity, and metatarsus adductus. The second index male was presented with symbrachydactyly, profound ID, and speech/hearing impairments...
September 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Reiji Yoshimura, Hikaru Hori, Asuka Katsuki, Kiyokazu Atake
Meige syndrome is a relatively rare type of oral facial dystonia. The dominant symptoms involve involuntary eye blinking and chin thrusting. Some patients may experience excessive tongue protrusion, squinting, muddled speech, or uncontrollable contraction of the platysma muscle. A 44-year-old Japanese male was suffering from schizophrenia. The initial presentation of his psychosis consisted of auditory hallucinations, delusions of persecution, psychomotor excitement, loosening association, and restlessness...
September 2016: Journal of UOEH
Yong Jia, Xiaoling Zhong, Jiangang Liu, Yong Guo
Through-wall-radar imaging is of interest for mapping the wall layout of buildings and for the detection of stationary targets within buildings. In this paper, we present an easy single-side two-location spotlight imaging method for both wall layout mapping and stationary target detection by utilizing multiple-input multiple-output (MIMO) through-wall-radar. Rather than imaging for building walls directly, the images of all building corners are generated to speculate wall layout indirectly by successively deploying the MIMO through-wall-radar at two appropriate locations on only one side of the building and then carrying out spotlight imaging with two different squint-views...
2016: Sensors
Brenna M Munro
Tracing a series of intertextually linked short stories from the 1990s to the present by women writers from Nigeria and its diaspora-Chimamanda Ngozi Adichie, Unoma Azuah, Chinelo Okparanta, and Lola Shoneyin-I suggest that although the figure of the African lesbian appears "new" in the context of heightened contemporary attention to the issue of homosexuality, this figure has a literary history. Ghanaian Ama Ata Aidoo's novel Our Sister Killjoy: Or, Reflections From A Black-Eyed Squint (1977) inaugurates this formation, in which the imagining of female same-sex desire is entangled with articulating the experience of migration under the shadow of imperial histories...
September 7, 2016: Journal of Lesbian Studies
Chao-Kai Kang, Chia-Shian Lin, Yao-Chung Hu, Shu-Chuan Tsai, Tsung-Han Lee
Milkfish, a species within the primitive teleost lineage Otocephala, can survive in water conditions ranging from hypo- to hyper-saline. This study explored the effects of environmental salinity on apical morphologies of ionocytes and the expression of villin homologs in the gills of milkfish acclimated to either seawater (SW) or fresh water (FW). Scanning electron microscopy revealed that the ionocytes in the gill filaments of SW and FW milkfish, respectively, cellular apical morphologies were hole-type and squint-type...
August 21, 2016: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
Deepa John, Karthik Muthusamy, Bhavagna Bandla, Sniya Valsa Sudhakar, Maya Thomas
Moya Moya Disease (MMD) is characterised by idiopathic vasculopathy affecting the terminal internal carotid arteries resulting in the formation of extensive collaterals at the base of the brain, leptomeninges and parenchymal regions with resultant infarcts and bleeds. Four children presented with clinico-radiological features suggestive of Moyamoya disease/syndrome. This includes global developmental delay, recurrent seizures, transient ischaemic attacks and impaired vision. The first patient had vision of 6/15 in both eyes with bilateral optic disc pallor...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
Teresa Tatoli, Donato Conteduca, Francesco Dell'Olio, Caterina Ciminelli, Mario N Armenise
The design of an integrated graphene-based fine-tunable optical delay line on silicon nitride for optical beamforming in phased-array antennas is reported. A high value of the optical delay time (τ<sub>g</sub>=920  ps) together with a compact footprint (4.15  mm<sup>2</sup>) and optical loss <27  dB make this device particularly suitable for highly efficient steering in active phased-array antennas. The delay line includes two graphene-based Mach-Zehnder interferometer switches and two vertically stacked microring resonators between which a graphene capacitor is placed...
June 1, 2016: Applied Optics
Kai Jing, Jia Xu, Zuzhen Huang, Di Yao, Teng Long
To realize ground moving target indication (GMTI) for a forward-looking array, we propose a novel synthetic aperture radar (SAR) system, called rotatable cross-track interferometry SAR (Ro-XTI-SAR), for squint-looking application in this paper. By changing the angle of the cross-track baseline, the interferometry phase component of squint-looking Ro-XTI-SAR caused by the terrain height can be approximately adjusted to zero, and then the interferometry phase of Ro-XTI-SAR is only sensitive to targets' motion and can be equivalent to the along track interferometry SAR (ATI-SAR)...
2016: Sensors
Kelly MacKenzie, Joanne Hancox, Hayley McBain, Daniel G Ezra, Gill Adams, Stanton Newman
BACKGROUND: Strabismus, also known as squint, can have a debilitating effect on a person's self-esteem, quality of life and mood, as well as increase their feelings of social anxiety and avoidance behaviour. Strabismus surgery can improve both the alignment of a person's eyes and, in appropriate cases, relieve symptoms such as double vision. However, evidence indicates that not all patients experience a meaningful improvement in their quality of life postsurgery. Pre-surgical psychosocial interventions have been found to improve patient reported outcomes in other long-term conditions...
2016: Cochrane Database of Systematic Reviews
Matthew S Yorek, Eric P Davidson, Pieter Poolman, Lawrence J Coppey, Alexander Obrosov, Amey Holmes, Randy H Kardon, Mark A Yorek
PURPOSE: Diagnosis of peripheral neuropathy (PN), which affects approximately 50% of the diabetic population, is subjective, with many patients seeking a diagnosis only after presenting with symptoms. Recently, in vivo confocal microscopy of subepithelial corneal nerve density has been promoted as a surrogate marker for early detection of PN, but imaging of corneal nerves requires sophisticated instrumentation, expertise in confocal imaging, cooperative patients, and automated analysis tools to derive corneal nerve density...
May 1, 2016: Investigative Ophthalmology & Visual Science
Suzan A AlKhater
BACKGROUND: Primary immunodeficiency disorders associated with autoimmunity are poorly understood. Central nervous system (CNS) vasculitis can complicate the courses of such entities, but it is underappreciated. Deletion of the dedicator of cytokinesis 8 (DOCK8) gene is considered to be the autosomal recessive form of hyperimmunoglobulin E syndrome which is a rare type of primary immunodeficiency disease characterized by elevated levels of IgE antibody, eczema, and recurrent staphylococcal infections...
2016: BMC Neurology
Luigi Bartalena, Lelio Baldeschi, Kostas Boboridis, Anja Eckstein, George J Kahaly, Claudio Marcocci, Petros Perros, Mario Salvi, Wilmar M Wiersinga
Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease, though severe forms are rare. Management of GO is often suboptimal, largely because available treatments do not target pathogenic mechanisms of the disease. Treatment should rely on a thorough assessment of the activity and severity of GO and its impact on the patient's quality of life. Local measures (artificial tears, ointments and dark glasses) and control of risk factors for progression (smoking and thyroid dysfunction) are recommended for all patients...
March 2016: European Thyroid Journal
Ashish R Deshwar, Serene C Chng, Lena Ho, Bruno Reversade, Ian C Scott
The Apelin receptor (Aplnr) is essential for heart development, controlling the early migration of cardiac progenitors. Here we demonstrate that in zebrafish Aplnr modulates Nodal/TGFβ signaling, a key pathway essential for mesendoderm induction and migration. Loss of Aplnr function leads to a reduction in Nodal target gene expression whereas activation of Aplnr by a non-peptide agonist increases the expression of these same targets. Furthermore, loss of Aplnr results in a delay in the expression of the cardiogenic transcription factors mespaa/ab...
2016: ELife
A Eckstein, D Dekowski, D Führer-Sakel, U Berchner-Pfannschmidt, J Esser
Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease and the full clinical picture can impair the quality of life of the patients considerably. Active inflammation can often be effectively treated by intravenous steroids/immunosuppression, however does not lead to full remission, since inflammation rather quickly results in irreversible fibrosis and increase of orbital fat. Very important is the control of risk factors (smoking cessation, good control of thyroid function, selenium supplementation) to prevent progression to severe stages...
April 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Rohit Saxena, Digvijay Singh, Shiva Prasad Gantyala, Sneha Aggarwal, Murli Manohar Sachdeva, Pradeep Sharma
AIM: To evaluate the profile of strabismus and amblyopia in patients presenting to a tertiary care institution in order to understand the disease burden. MATERIALS AND METHODS: A retrospective, prospective hospital-based observational study was conducted at a tertiary level eye care hospital in India. All patients with strabismus or amblyopia who presented over a 1-year period were identified and referred to the squint clinic, where they were evaluated with a detailed clinical history and examination...
April 2016: Indian Journal of Community Medicine
Cynthia Lions, Lucile Colleville, Emmanuel Bui-Quoc, Maria Pia Bucci
OBJECTIVE: The first goal of the present study is to analyze the postural control in strabismic children in four different visual conditions (eyes open, eyes closed and monocular viewing with squint eye and non-squint eye). Secondly, we wish to explore the effect of strabismus surgery in postural control. METHOD: Postural stability was recorded with a platform (TechnoConcept) in 23 strabismic children aged from 4.4 to 14.8 years old (mean age: 8.4 years); 12 of these children were also examined at least two months after strabismus surgery...
March 23, 2016: Neuroscience Letters
Suk-Gyu Ha, Seung-Hyun Kim
PURPOSE: To examine clinical preoperative and postoperative symptoms and changes in exotropia according to constancy and age. METHODS: A survey was conducted of 50 patients on the day before and 1 month after exotropia surgery. Survey results were analyzed by type of exotropia at presentation and age. Changes in subjective symptoms from preoperatively to postoperatively were examined for stereopsis (5 items), asthenopia (5 items), and appearance (5 items). Each item was rated on a 5-point scale ranging from 0 to 4...
January 2016: Journal of Pediatric Ophthalmology and Strabismus
Andreas Schnapp, Ann-Christin Niehoff, Annika Koch, Klaus Dreisewerd
Silver-assisted laser desorption/ionization mass spectrometry can be used for the analysis of small molecules. For example, adduct formation with silver cations enables the molecular analysis of long-chain hydrocarbons, which are difficult to ionize via conventional matrix-assisted laser desorption ionization (MALDI). Here we used highly porous silver foils, produced by etching with nitric acid, as sample substrates for LDI mass spectrometry. As model system for the analysis of complex lipid mixtures, cuticular extracts of fruit flies (Drosophila melanogaster) and worker bees (Apis mellifera) were investigated...
July 15, 2016: Methods: a Companion to Methods in Enzymology
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