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computed tomography perfusion

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https://www.readbyqxmd.com/read/30017466/-evaluation-of-the-characteristics-of-aortic-dissection-by-computed-angio-tomography-in-the-mexican-population
#1
Luis Burboa-Noriega, Jesús Burboa-Noriega, César Cristancho-Rojas, Sergio Criales-Vera
OBJECTIVE: To review aortic dissection (AD) in the Mexican population. METHOD: A retrospective study was conducted using 434 medical records of patients with aortic angio-tomography between November 2014 and October 2015. A sample was obtained of 32 patients with a first time diagnosis of AD. An analysis was performed of the dissections according to gender, age group, Stanford/De Bakey classification, and mortality rate 6 months after diagnosis. Statistical analysis was performed by obtaining the Chi squared index for the independent variables of gender, Marfan syndrome, systemic arterial hypertension, as well as calcified atheromatous disease in association with dissection subtypes, re-entry sites, and hypo-perfusion signs...
July 13, 2018: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/30015395/diagnosing-and-grading-heart-failure-with-tomographic-perfusion-lung-scintigraphy-validation-with-right-heart-catheterization
#2
Jonas Jögi, Mariam Al-Mashat, Göran Rådegran, Marika Bajc, Håkan Arheden
AIMS: Pulmonary congestion remains a diagnostic challenge in patients with heart failure (HF). The recommended method, chest X-ray (CXR), lacks in accuracy, whereas quantitative tomographic lung scintigraphy [ventilation/perfusion single-photon emission computed tomography (V/P SPECT)] has shown promising results but needs independent validation. The aim of this study is to evaluate V/P SPECT as a non-invasive method to assess and quantify pulmonary congestion in HF patients, using right heart catheterization as reference method...
July 17, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/30013926/comparison-between-simultaneously-acquired-arterial-spin-labeling-and-18-f-fdg-pet-in-mesial-temporal-lobe-epilepsy-assisted-by-a-pet-mr-system-and-seeg
#3
Yi-He Wang, Yang An, Xiao-Tong Fan, Jie Lu, Lian-Kun Ren, Peng-Hu Wei, Bi-Xiao Cui, Jia-Lin Du, Chao Lu, Di Wang, Hua-Qiang Zhang, Yong-Zhi Shan, Guo-Guang Zhao
Objective: In the detection of seizure onset zones, arterial spin labeling (ASL) can overcome the limitations of positron emission tomography (PET) with 18 F-fluorodeoxyglucose (18 F-FDG), which is invasive, expensive, and radioactive. PET/magnetic resonance (MR) systems have been introduced that allow simultaneous performance of ASL and PET, but comparisons of these techniques with stereoelectroencephalography (SEEG) and comparisons among the treatment outcomes of these techniques are still lacking...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/30013913/which-of-the-branched-chain-amino-acids-increases-cerebral-blood-flow-in-hepatic-encephalopathy-a-double-blind-randomized-trial
#4
Fernando Gomes Romeiro, Marjorie do Val Ietsugu, Letícia de Campos Franzoni, Laís Augusti, Matheus Alvarez, Lívia Alves Amaral Santos, Talles Bazeia Lima, Kátia Hiromoto Koga, Sônia Marta Moriguchi, Carlos Antonio Caramori, Giovanni Faria Silva, Luiz Eduardo Gomes Garcia Betting
Branched-chain amino acids increase the brain perfusion of patients with hepatic encephalopathy (HE), but the amino acid and the mechanisms involved are still unknown. This study compared brain perfusion and clinical improvement during leucine or isoleucine supplementation. After randomization, 27 subjects with cirrhosis and HE received leucine or isoleucine supplements for one year. Brain single Photon Emission Computed Tomography (SPECT) and dynamic brain scintigraphy (DBS) were performed pretreatment and at 1, 8 and 12 months of supplementation...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/30012527/a-randomized-comparison-of-radiation-therapy-techniques-in-the-management-of-node-positive-breast-cancer-primary-outcomes-analysis
#5
Reshma Jagsi, Kent A Griffith, Jean M Moran, Edward Ficaro, Robin Marsh, Robert T Dess, Eugene Chung, Adam L Liss, James A Hayman, Charles S Mayo, Kevin Flaherty, James Corbett, Lori Pierce
PURPOSE: Although inverse-planned intensity modulated radiotherapy (IMRT) and deep inspiration breath hold (DIBH) may allow for more conformal dose distributions, it is unknown whether using these technologies reduces cardiac or pulmonary toxicity of breast radiotherapy. METHODS AND MATERIALS: A randomized controlled trial compared IMRT-DIBH versus standard, free-breathing, forward-planned, three-dimensional conformal radiotherapy in patients with left-sided, node-positive breast cancer in whom the internal mammary nodal region was targeted...
August 1, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/30010229/the-frequency-of-substantial-salvageable-penumbra-in-thrombectomy-ineligible-patients-with-acute-stroke
#6
Mersedeh Bahr Hosseini, Graham Woolf, Latisha K Sharma, Jason D Hinman, Neal M Rao, Bryan Yoo, Reza Jahan, Sidney Starkman, May Nour, Radoslav Raychev, David S Liebeskind, Jeffrey L Saver
BACKGROUND AND PURPOSE: Endovascular therapy (ET) has become the standard of care for selected patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO). However, many LVO or medium vessel occlusion (MVO) patients are ineligible for ET, including some who harbor salvageable tissues. To develop complementary therapies for these patients, it is important to delineate their prevalence, clinical features, and outcomes. METHODS: In a prospectively maintained database, we reviewed consecutive AIS patients between December 2015 and September 2016...
July 16, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/30010157/effect-of-pre-surgery-assessments-on-the-prognosis-of-patients-received-extracranial-intracranial-bypass-surgery
#7
Chen Li, Xuhua Cao, Zhizhao Ma, Xiaofeng Sun, Fuguang Hu, Liqun Wang
BACKGROUND: Extracranial-intracranial (EC-IC) bypass surgery has been used to improve the conditions of cerebral ischemia symptoms for selected patients resulting from diverse complications such as stroke and atherosclerotic disease. However, several clinical trials showed EC-IC bypass surgery failed to prevent recurrent ischemic stroke in certain patients. OBJECTIVE: Our clinical trial aimed to investigate whether there is a correlation between pre-surgery assessments and prognosis of patients received EC-IC bypass operation...
June 28, 2018: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/30008186/effect-of-a-clinical-flowchart-incorporating-wells-score-perc-rule-and-age-adjusted-d-dimer-on-pulmonary-embolism-diagnosis-scan-rates-and-diagnostic-yield
#8
Paul Buntine, Francis Thien, John Stewart, Yee Ping Woo, Martin Koolstra, Lindsay Bridgford, Mineesh Datta, Stella M Gwini
OBJECTIVE: To assess the association between the use of a flowchart incorporating Wells score, PERC rule and age-adjusted D-dimer and subsequent imaging and yield rates of computed tomography pulmonary angiogram and nuclear medicine ventilation perfusion scans being ordered in the ED for the assessment of pulmonary embolism. METHODS: A flowchart governing ED pulmonary embolism investigation was introduced across three EDs in Melbourne, Australia for a 12 month period...
July 15, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/30006891/comparison-of-cone-beam-tomography-and-cross-sectional-imaging-for-volumetric-and-dosimetric-calculations-in-resin-yttrium-90-radioembolization
#9
Marco Ertreo, Hailey Choi, David Field, Jonathan W Lischalk, Emil Cohen, George E Lynskey, Theresa Caridi, Donna Buckley, Keith Unger, Alexander Y Kim
PURPOSE: To compare the use of cone-beam computed tomography versus contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI) in the calculation of liver volume and planned dose for yttrium-90 radioembolization. MATERIALS AND METHODS: The study retrospectively assessed 47 consecutive patients who underwent resin Y-90 radioembolization consecutively over a 2-year period at a single center. Volume calculation software was used to determine perfused lobar liver volumes from cone-beam CT (CBCT) images obtained during mapping angiography...
July 13, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29996650/radioiodinated-pentixather-for-spect-imaging-of-the-chemokine-receptor-cxcr4-expression-in-rat-myocardial-infarction-reperfusion-models
#10
Jindian Li, Chenyu Peng, Zhide Guo, Changrong Shi, Rongqiang Zhuang, Xingfang Hong, Xiangyu Wang, Duo Xu, Pu Zhang, Deliang Zhang, Ting Liu, Xinhui Su, Xianzhong Zhang
The purpose of this study is to develop a specific CXCR4-targeting radioiodinated agent (125I/131I-pentixather) for single-photon emission computed tomography (SPECT) imaging of CXCR4 expression in myocardial infarction/reperfusion (MI/R) rat models. After SPECT/CT imaging with 125I-pentixather at 4, 12, 36 h, 3 and 7 d after MI/R, the models were validated by ex vivo autoradiography, TTC staining and immunohistochemistry, and in vivo echocardiography and classical 99mTc-MIBI perfusion imaging, respectively...
July 12, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29992262/myocardial-perfusion-during-atrial-fibrillation-in-patients-with-non-ischaemic-systolic-heart-failure-a-cross-sectional-study-using-rubidium-82-positron-emission-tomography-computed-tomography
#11
Christina Byrne, Philip Hasbak, Andreas Kjær, Jens Jakob Thune, Lars Køber
Aims: Patients with non-ischaemic systolic heart failure often have reduced myocardial blood flow without significant coronary atherosclerosis. Likewise, patients with atrial fibrillation (AF) have reduced myocardial perfusion during AF compared with sinus rhythm. The aim of this study was to explore whether there is an additive negative effect of AF during scan on the myocardial perfusion in patients with non-ischaemic systolic heart failure. Methods and results: We included 27 young healthy controls and 114 patients with non-ischaemic systolic heart failure to a Rubidium-82 positron emission tomography/computed tomography perfusion scan (23 with AF during scan)...
July 9, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29991840/pulmonary-thromboembolism-new-diagnostic-imaging-techniques
#12
Julia Noschang, Marcos Duarte Guimarães, Diogo Fábio Dias Teixeira, Juliana Cristina Duarte Braga, Bruno Hochhegger, Pablo Rydz Pinheiro Santana, Edson Marchiori
The accurate diagnosis of pulmonary thromboembolism is essential to reducing the morbidity and mortality associated with the disease. The diagnosis of pulmonary thromboembolism is challenging because of the nonspecific nature of the clinical profile and the risk factors. Imaging methods provide the definitive diagnosis. Currently, the imaging method most commonly used in the evaluation of pulmonary thromboembolism is computed tomography. The recent development of dual-energy computed tomography has provided a promising tool for the evaluation of pulmonary perfusion through iodine mapping...
May 2018: Radiologia Brasileira
https://www.readbyqxmd.com/read/29991309/nihss-sub-item-scores-predict-collateral-flow-in-acute-middle-cerebral-artery-infarction
#13
Jaechun Hwang, Mi Ji Lee, Jong-Won Chung, Oh Young Bang, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee
Background and purpose The status of collateral vessels has important clinical implications in acute ischemic stroke. To evaluate which components of ischemic symptoms were predictive of pretreatment collateral status, we tested the hypothesis that sub-item scores from the National Institutes of Health Stroke Scale (NIHSS) are associated with leptomeningeal collateral status in acute ischemic stroke with middle cerebral artery (MCA) occlusion. Methods This study included consecutive patients with acute M1 occlusion who underwent revascularization treatment for acute MCA infarction...
January 1, 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29979416/diagnostic-value-of-quantitative-coronary-flow-reserve-and-myocardial-blood-flow-estimated-by-dynamic-320-mdct-scanning-in-patients-with-obstructive-coronary-artery-disease
#14
Masahiko Obara, Masanao Naya, Noriko Oyama-Manabe, Tadao Aikawa, Yuuki Tomiyama, Tsukasa Sasaki, Yasuka Kikuchi, Osamu Manabe, Chietsugu Katoh, Nagara Tamaki, Hiroyuki Tsutsui
We have developed the method for dynamic 320-row multidetector computed tomography (MDCT)-derived quantitative coronary flow reserve (CFRCT) and hyperemic myocardial blood flow (MBFCT). We evaluated diagnostic value of CFRCT and hyperemic MBFCT for detecting obstructive coronary artery disease (CAD) in per-patient and per-vessel analysis, and their relations with the severity of CAD burden.Adenosine stressed and rest dynamic myocardial perfusion MDCT were prospectively performed in patients with known or suspected CAD...
July 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29979286/neuroimaging-correlates-of-periodic-discharges
#15
Aline Herlopian, Aaron F Struck, Eric Rosenthal, Brandon M Westover
Despite being first described over 50 years ago, periodic discharges continue to generate controversy as to whether they are always, sometimes, or never "ictal." Investigators and clinicians have proposed adjunctive markers to help clarify this distinction-in particular measures of perfusion and metabolism. Here, we review the growing number of neuroimaging studies using Fluorodeoxyglucose-PET, MRI diffusion, Magnetic resonance perfusion, Single Photon Emission Computed Tomography, and Magnetoencepgalography to gain further insight into the physiology and clinical significance of periodic discharges...
July 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29971980/postoperative-transient-neurologic-dysfunction-a-proposal-for-pathophysiology
#16
Ji Hoon Phi, Seung Jin Lee, Hyun Seung Kang, Jeong Eun Kim, Seung Ki Kim, Won Sang Cho, Seo Young Lee
BACKGROUND AND PURPOSE: Sudden neurological deterioration which cannot be explained by structural change, ischemia or seizure is often observed among neurosurgical patients. We aimed to provide new insight into the pathophysiology of postoperative transient neurologic dysfunction. METHODS: We describe prolonged but fully reversible focal neurologic dysfunction of unknown origin based on the initial evaluation in 8 patients who had received encephalo-duro-arterio-synangiosis for moyamoya disease...
July 2018: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/29969956/reversible-cerebral-vasoconstriction-complicated-with-brain-infarction-immediately-after-carotid-artery-stenting
#17
Eiji Higashi, Takeshi Uwatoko, Taichiro Mizokami, Yusuke Sakaki, Shuji Sakata, Hiroshi Sugimori
Reversible cerebral vasoconstriction is a very rare complication after carotid artery stenting (CAS). It has been reported to occur more than several hours after CAS and to have a good clinical course. A 73-year-old man underwent CAS for a high-grade symptomatic stenosis of his left carotid artery. Immediately after CAS, he had consciousness disturbance and right hemiparesis. We first suspected hyperperfusion syndrome, but antihypertensive therapy exacerbated his symptoms. On repeated postoperative angiography, the middle cerebral artery (MCA) appeared to become progressively narrower...
January 1, 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29968157/stomach-interference-in-82-rb-pet-myocardial-perfusion-imaging
#18
Thomas Rasmussen, Andreas Kjær, Philip Hasbak
BACKGROUND: 82 Rubidium(82 Rb)-positron-emission-tomography (PET) is prone to some of the same imaging artifacts as single-photon-emission-computed-tomography myocardial perfusion imaging (MPI) including interference from excessive subdiaphragmatic activity. Our aim was to determine associations between clinical parameters and MPI interference including any potential correlation between interference severity and stomach volume. METHODS AND RESULTS: Two hundred men and women fasted two hours prior to standard clinical 82 Rb myocardial perfusion rest/stress PET...
July 2, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29963580/development-of-a-pulmonary-imaging-biomarker-pipeline-for-phenotyping-of-chronic-lung-disease
#19
Fumin Guo, Dante Capaldi, Miranda Kirby, Khadija Sheikh, Sarah Svenningsen, David G McCormack, Aaron Fenster, Grace Parraga
We designed and generated pulmonary imaging biomarker pipelines to facilitate high-throughput research and point-of-care use in patients with chronic lung disease. Image processing modules and algorithm pipelines were embedded within a graphical user interface (based on the .NET framework) for pulmonary magnetic resonance imaging (MRI) and x-ray computed-tomography (CT) datasets. The software pipelines were generated using C++ and included: (1) inhaled <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mmultiscripts> <mml:mrow> <mml:mi>He</mml:mi> </mml:mrow> <mml:mprescripts/> <mml:none/> <mml:mrow> <mml:mn>3</mml:mn> </mml:mrow> </mml:mmultiscripts> <mml:mo>/</mml:mo> <mml:mmultiscripts> <mml:mrow> <mml:mi>Xe</mml:mi> </mml:mrow> <mml:mprescripts/> <mml:none/> <mml:mrow> <mml:mn>129</mml:mn> </mml:mrow> </mml:mmultiscripts> <mml:mtext> </mml:mtext> <mml:mi>MRI</mml:mi> </mml:mrow> </mml:math> ventilation and apparent diffusion coefficients, (2) CT-MRI coregistration for lobar and segmental ventilation and perfusion measurements, (3) ultrashort echo-time <mml:math xmlns:mml="http://www...
April 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29962073/cardiac-shock-wave-therapy-improves-myocardial-perfusion-and-preserves-left-ventricular-mechanics-in-patients-with-refractory-angina-a-study-with-speckle-tracking-echocardiography
#20
Anderson S Duque, Conrado L Ceccon, Wilson Mathias, Joana Diniz Majesky, Luis H Gowdak, João C N Sbano, Luis Antonio Machado Cesar, Maria Cristina Abduch, Márcio S M Lima, Paulo M M Dourado, Cecilia B B V Cruz, Jeane M Tsutsui
BACKGROUND: Cardiac shockwave therapy (CSWT) is a new potential option for the treatment of patients with chronic coronary disease and refractory angina (RA). We aimed to study the effects of CSWT on left ventricular myocardial perfusion and mechanics in patients with RA. METHOD: We prospectively studied 19 patients who underwent CSWT. Left ventricular mechanics were evaluated by speckle tracking echocardiography (STE), and myocardial perfusion by single-photon emission computed tomography, using stress/rest-Technetium-99 m Sestamibi, for determination of summed stress score (SSS)...
July 1, 2018: Echocardiography
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