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computed tomography perfusion

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https://www.readbyqxmd.com/read/27931057/-quantification-of-ventilation-inflammation-perfusion-and-structure-vips
#1
J Renne, J Vogel-Claussen
Technical innovation in pulmonary imaging during the recent years has led to a shift from morphological description of pulmonary pathologies to regional quantification of pulmonary function. This article summarizes current clinical standards in pulmonary imaging and introduces the reader to new innovative techniques of functional lung imaging. In the context of actual clinical studies for COPD, asthma, pulmonary hypertension and cystic fibrosis the application of quantitative imaging methods using computed tomography and magnetic resonance imaging is demonstrated and possible future applications are discussed...
December 2016: Pneumologie
https://www.readbyqxmd.com/read/27928672/pure-laparoscopic-right-anterior-sectionectomy-for-hepatocellular-carcinoma-with-great-vascular-exposure
#2
Varvara A Kirchner, Ki-Hun Kim, Seok-Hwan Kim, Sang-Kyung Lee
BACKGROUND: Laparoscopic hepatectomy is a common procedure that has been reported frequently [1-3]. However, laparoscopic resection of tumors located in hepatic segments 5 and/or 8 remains a technically difficult procedure as it requires two transection planes [4]. Furthermore, there are a greater number of hepatic vein and glissonian pedicle branches that require a division as compared to other hepatectomy operations. In this report, we present a pure laparoscopic right anterior sectionectomy (RAS) for hepatocellular carcinoma (HCC)...
December 7, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27924778/evaluation-of-anterior-mediastinal-solid-tumors-by-ct-perfusion-a-preliminary-study
#3
Selim Bakan, Sedat Giray Kandemirli, Atilla Süleyman Dikici, Ezel Erşen, Onur Yıldırım, Cesur Samancı, Şebnem Batur, Deniz Çebi Olgun, Fatih Kantarcı, Canan Akman
PURPOSE: We aimed to assess the role of computed tomography (CT) perfusion in differentiation of thymoma from thymic hyperplasia, lymphoma, thymic carcinoma, and lung cancer invading anterior mediastinum. METHODS: In this study, 25 patients with an anterior mediastinal lesion underwent CT perfusion imaging from January 2015 to February 2016. Diagnoses included thymoma (n=7), thymic hyperplasia (n=8), lymphoma (n=4), thymic carcinoma (n=3), and invasive lung cancer (n=3)...
December 7, 2016: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/27924174/feasibility-study-of-computational-fluid-dynamics-simulation-of-coronary-computed-tomography-angiography-based-on-dual-source-computed-tomography
#4
Jing Lu, Jie Yu, Heshui Shi
BACKGROUND: Adding functional features to morphological features offers a new method for non-invasive assessment of myocardial perfusion. This study aimed to explore technical routes of assessing the left coronary artery pressure gradient, wall shear stress distribution and blood flow velocity distribution, combining three-dimensional coronary model which was based on high resolution dual-source computed tomography (CT) with computational fluid dynamics (CFD) simulation. METHODS: Three cases of no obvious stenosis, mild stenosis and severe stenosis in left anterior descending (LAD) were enrolled...
January 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27923226/intraoperative-tumoral-bleeding-of-hypervascular-medulloblastoma-after-ventricular-drainage-a-case-report
#5
Han-Seung Ryu, Tae-Young Jung, Moon-Soo Han, Seul-Ki Kim, Kyung-Hwa Lee
We report a rare case of intraoperative tumoral bleeding of a hypervascular medulloblastoma. A 12-year-old girl presented with dizziness and nausea. Brain magnetic resonance (MR) images revealed an approximately 4.2-cm enhanced mass on the cerebellar vermis associated with mild perilesional edema and increased cerebral blood volume. Angiography showed tumoral staining and developed occipital and circular dural sinuses in the venous phase. A suboccipital craniotomy was performed. To relieve the intracranial pressure, cerebrospinal fluid (CSF) was drained via a lateral ventricular catheter in the occipital horn...
December 7, 2016: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27920268/clinical-value-of-perfusion-abnormalities-of-brain-on-technetium-99m-hmpao-single-photon-emission-computed-tomography-in-children-with-sydenham-chorea
#6
Sara Maria Delle Acque Giorgio, Maria Grazia Caprio, Flavia Galante, Giustina Russo, Alfonso Romano, Emilia Vergara, Maria Alessio, Alberto Cuocolo
We evaluated whether perfusion brain abnormalities by single-photon emission computed tomography (SPECT) imaging improves diagnostic and prognostic assessment in Sydenham chorea. Twenty-three children with acute autoimmune chorea underwent technetium-99m hexamethylpropyleneamine oxime brain SPECT imaging. In 16 children, SPECT was repeated during the follow-up. A pattern of basal ganglia hyperperfusion was observed in 20 (87%) patients. In 4 of 10 patients with generalized chorea, perfusion was comparable in right and left striatum and right and left thalamus...
December 5, 2016: Journal of Child Neurology
https://www.readbyqxmd.com/read/27916243/safe-reentry-for-false-aneurysm-operations-in-high-risk-patients
#7
Gian Luca Martinelli, Attilio Cotroneo, Philippe Primo Caimmi, Gabriele Musica, David Barillà, Edmond Stelian, Angelo Romano, Eugenio Novelli, Luca Renzi, Marco Diena
BACKGROUND: In the absence of a standardized safe surgical reentry strategy for high-risk patients with large or anterior postoperative aortic false aneurysm (PAFA), we aimed to describe an effective and safe approach for such patients. METHODS: We prospectively analyzed patients treated for PAFA between 2006 and 2015. According to the preoperative computed tomography scan examination, patients were divided into two groups according to the anatomy and extension of PAFA: in group A, high-risk PAFA (diameter ≥3 cm) developed in the anterior mediastinum; in group B, low-risk PAFA (diameter <3 cm) was situated posteriorly...
December 1, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27913507/diagnosis-of-suspected-venous-thromboembolism
#8
Clive Kearon
The primary goal of diagnostic testing for venous thromboembolism (VTE) is to identify all patients who could benefit from anticoagulant therapy. Test results that identify patients as having a ≤2% risk of VTE in the next 3 months are judged to exclude deep vein thrombosis (DVT) or pulmonary embolism (PE). Clinical evaluation, with assessment of: (1) clinical pretest probability (CPTP) for VTE; (2) likelihood of important alternative diagnoses; and (3) the probable yield of D-dimer and various imaging tests, guide which tests should be performed...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27908971/13n-ammonia-pet-ct-detection-of-myocardial-perfusion-abnormalities-in-beagle-dogs-after-local-heart-irradiation
#9
Jianbo Song, Rui Yan, Zhifang Wu, Jianguo Li, Min Yan, Xinzhong Hao, Jianzhong Liu, Sijin Li
: To determine the potential value of (13)N-ammonia positron emission tomography (PET)/computed tomography (CT) myocardial perfusion imaging (MPI) for detection of myocardial perfusion changes at early stage induced by radiation damage. METHODS: Thirty-six Beagle dogs were randomly divided into the control (n = 18) or the irradiation groups (n = 18). The irradiation group underwent local irradiation to the left ventricular anterior cardiac wall with a single dose of 20 Gy, whereas the control group received sham irradiation...
December 1, 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/27908505/diagnostic-advantage-of-stress-computed-tomography-myocardial-perfusion-over-single-photon-emission-computed-tomography-for-the-assessment-of-myocardial-ischemia
#10
Yasushi Ueki, Atsushi Izawa, Daisuke Kashiwagi, Shigeki Nishiyama, Shinichi Aso, Chihiro Suzuki, Shumpei Sakurai, Kazuhiro Oguchi, Yoshikazu Yazaki, Uichi Ikeda, Koichiro Kuwahara
BACKGROUND: This study compared adenosine stress computed tomography myocardial perfusion (CTP) with single-photon emission computed tomography (SPECT) in the diagnosis of functionally significant coronary artery stenosis using fractional flow reserve (FFR) as reference standard. METHODS: We included a total of 93 coronary arteries from 31 patients in whom at least one vessel with ≥50% stenosis was detected with computed tomography coronary angiography. All patients underwent both SPECT and adenosine stress CTP, followed by invasive coronary angiography (ICA) and FFR...
November 28, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27908148/local-attenuation-curve-optimization-framework-for-high-quality-perfusion-maps-in-low-dose-cerebral-perfusion-ct
#11
Vincent Van Nieuwenhove, Geert Van Eyndhoven, K Joost Batenburg, Nico Buls, Jef Vandemeulebroucke, Jan De Beenhouwer, Jan Sijbers
PURPOSE: Cerebral perfusion x-ray computed tomography (PCT) is a powerful tool for noninvasive imaging of hemodynamic information throughout the brain. Conventional PCT requires the brain to be imaged multiple times during the perfusion process, and hence radiation dose is a major concern. The authors propose a PCT reconstruction algorithm that allows for lowering the dose while maintaining a high quality of the perfusion maps. It relies on an accurate estimation of the arterial input function (AIF), which in turn depends on the quality of the attenuation curves in the arterial region...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27901210/effects-of-alveolar-bone-displacement-with-segmental-osteotomy-micro-ct-and-histomorphometric-analysis-in-rats
#12
Taegun Kim, Won Lee, Sang-Ho Baek, Sungwoon Pyo, Yoon-Ah Kook, Mohamed Bayome, Insoo Kim
The purpose of this study was to evaluate the effects of segmental osteotomy on the blood vessels and osteoclasts in rats using micro-computed tomography (micro-CT) and histomorphometric analysis. After segmental osteotomy was performed around the maxillary first molars of 36 male Sprague-Dawley rats (n = 72), the samples were divided into a control group (no displacement), 0.5 D group (0.5 mm buccal displacement) and 1.0 D group (1.0 mm buccal displacement) (n = 24/group). At 1, 2, 4 and 8 weeks after surgery, changes in the blood vessel volume were investigated using micro-CT with perfusion of radiopaque silicone rubber...
November 28, 2016: Brazilian Oral Research
https://www.readbyqxmd.com/read/27900758/99mtc-hmpao-perfusion-spect-ct-in-the-diagnosis-of-brain-death
#13
Thorsten Derlin, Desiree Weiberg
This report describes a case of brain death (BD) evaluated by 99mTc-hexamethylpropylene amine oxime (HMPAO) single photon emission tomography/computed tomography (SPECT/CT). A 16-year-old boy with a history of rapid unexpected brain herniation due to pilocytic astrocytoma underwent 99mTc-HMPAO SPECT/CT for evaluation of brain death in the context of organ donation. Flow images demonstrated lack of blood flow to the brain, and delayed images showed absence of demonstrable radionuclide activity within the brain...
2016: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/27896227/stress-first-single-photon-emission-computed-myocardial-perfusion-imaging
#14
C I Aquino, M Scarano, F Squame, G Casaburi, S L Nori, L Pace
BACKGROUND: Myocardial perfusion imaging (MPI) with single photon emission tomography (SPET) is widely used in coronary artery disease evaluation. Recently major dosimetric concerns have arisen. The aim of this study was to evaluate if a pre-test scoring system could predict the results of stress SPET MPI, thus avoiding two radionuclide injections. METHODS: All consecutive patients (n=309) undergoing SPET MPI during the first 6 months of 2014 constituted the study group...
November 2016: Translational Medicine @ UniSa
https://www.readbyqxmd.com/read/27895453/a-case-of-a-living-related-kidney-transplantation-after-ex-vivo-repair-of-the-donor-renal-artery-aneurysm
#15
P Christopoulos, A Faryal, M Dosani, D Rix, D Talbot
BACKGROUND: Kidney transplantation is the definite surgical treatment for end-stage renal disease. Shortage of organs and the increasing number of patients with end-stage renal disease has led to an expansion of the selection criteria promoting the use of organs from marginal donors. Use of kidneys with renal artery aneurysm (RAA) is one such example. Description of the case: We report a case of living-related kidney transplantation from a 46-year-old female donor with unilateral RAA to her 68-year-old father...
January 2016: Hippokratia
https://www.readbyqxmd.com/read/27893680/the-value-of-ezis-analysis-of-tc-99m-ecd-spect-on-identifying-cerebellar-hypoperfusion-in-a-patient-with-superficial-siderosis-a-case-report
#16
Cheng-Yu Wei, Tai-Yi Chen, Ian Shih, Pai-Yi Chiu, Guang-Uei Hung, Hiroshi Matsuda
INTRODUCTION: Brain perfusion single photon computed tomography (SPECT) is a functional imaging modality and has been widely utilized in evaluation of various kinds of neurological disorders. Easy z-score imaging system (eZIS) is a computer-assisted statistical analysis, based on the comparison with age-classified ethyl cysteinate dimer (ECD) normal database, which provides objectively interpretation of Tc-99m ECD brain perfusion SPECT.Here we presented a 64-year-old male with dizziness, spin sensation, nausea, and vomiting in the emergency room, and brain computed tomography scan showed only small hypodensity lesion in cerebellum...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27891826/ct-brain-perfusion-a-static-phantom-study-of-contrast-to-noise-ratio-and-radiation-dose
#17
Stewart M Midgley, Damien L Stella, Bruce Cv Campbell, Francesca Langenberg, Paul F Einsiedel
INTRODUCTION: Computed tomography perfusion (CTP) is increasingly employed in the diagnosis and management of ischaemic stroke but radiation dose can be significant and optimising contrast-to-noise ratio (CNR) is challenging. This study aimed to quantify and optimise the balance between CNR as a surrogate for image quality and radiation dose. METHODS: A perspex head phantom with vials of dilute contrast agent was scanned using a Siemens Definition Flash 128-slice scanner...
November 27, 2016: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/27886985/efficacy-of-lens-protection-systems-dependency-on-different-cranial-ct-scans-in-the-acute-stroke-setting
#18
Nika Guberina, Michael Forsting, Adrian Ringelstein
To evaluate the dose-reduction potential with different lens protectors for patients undergoing cranial computed tomography (CT) scans. Eye lens dose was assessed in vitro (α-Al2O3:C thermoluminescence dosemeters) using an Alderson-Rando phantom(®) in cranial CT protocols at different CT scanners (SOMATOM-Definition-AS+(®)(CT1) and SOMATOM-Definition-Flash(®) (CT2)) using two different lens-protection systems (Somatex(®) (SOM) and Medical Imaging Systems(®) (MIS)). Summarised percentage of the transmitted photons: (1) CT1 (a) unenhanced CT (nCT) with gantry angulation: SOM = 103%, MIS = 111%; (2) CT2 (a) nCT without gantry angulation: SOM = 81%, MIS = 91%; (b) CT angiography (CTA) with automatic dose-modulation technique: SOM = 39%, MIS = 74%; (c) CTA without dose-modulation technique: SOM = 22%, MIS = 48%; (d) CT perfusion: SOM = 44%, MIS = 69%...
November 24, 2016: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27886421/pathophysiology-of-dyspnoea-in-acute-pulmonary-embolism-a-cross-sectional-evaluation
#19
Olivier Sanchez, Aurore Caumont-Prim, Elisabeth Riant, Laurent Plantier, Martin Dres, Bruno Louis, Marie-Anne Collignon, Benoit Diebold, Guy Meyer, Claudine Peiffer, Christophe Delclaux
BACKGROUND AND OBJECTIVE: Dyspnoea in pulmonary embolism (PE) remains poorly characterized. Little is known about how to measure intensity or about the underlying mechanisms that may be related to ventilatory abnormalities, alveolar dead space ventilation or modulating factors such as psychological modulate. We hypothesized that dyspnoea would mainly be associated with pulmonary vascular obstruction and its pathophysiological consequences, while the sensory-affective domain of dyspnoea would be influenced by other factors...
November 25, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27880734/the-role-of-necrosis-acute-hypoxia-and-chronic-hypoxia-in-18-f-fmiso-pet-image-contrast-a-computational-modelling-study
#20
Daniel R Warren, Mike Partridge
Positron emission tomography (PET) using (18)F-fluoromisonidazole (FMISO) is a promising technique for imaging tumour hypoxia, and a potential target for radiotherapy dose-painting. However, the relationship between FMISO uptake and oxygen partial pressure ([Formula: see text]) is yet to be quantified fully. Tissue oxygenation varies over distances much smaller than clinical PET resolution (<100 μm versus  ∼4 mm), and cyclic variations in tumour perfusion have been observed on timescales shorter than typical FMISO PET studies (∼20 min versus a few hours)...
December 21, 2016: Physics in Medicine and Biology
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