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https://www.readbyqxmd.com/read/29731926/practical-approach-to-lung-health-experience-from-the-republic-of-macedonia
#1
Biljana Ilievska-Poposka, Maja Zakoska, Stefan Talevski
BACKGROUND: Among the adults and children aged 5 yrs who attend PHC settings, 20-30% seeks to care for respiratory symptoms. Over 80-90% of the respiratory patients suffer from acute respiratory infections (ARI), followed by chronic obstructive pulmonary diseases (COPD), asthma, and less frequently with pneumonia and tuberculosis (TB). To improve the quality of care in patients who seek assistance for respiratory symptoms in PHC settings and the efficiency of respiratory service delivery within healthcare systems, WHO has designated several initiatives among which one is PAL (Practical Approach to Lung Health)...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29676069/perceptions-of-severe-asthma-and-asthma-copd-overlap-syndrome-among-specialists-a-questionnaire-survey
#2
Sang Heon Kim, Ji Yong Moon, Jae Hyun Lee, Ga Young Ban, Sujeong Kim, Mi Ae Kim, Joo Hee Kim, Min Hye Kim, Chan Sun Park, So Young Park, Hyouk Soo Kwon, Jae Woo Kwon, Jae Woo Jung, Hye Ryun Kang, Jong Sook Park, Tae Bum Kim, Heung Woo Park, You Sook Cho, Kwang Ha Yoo, Yeon Mok Oh, Byung Jae Lee, An Soo Jang, Sang Heon Cho, Hae Sim Park, Choon Sik Park, Ho Joo Yoon
PURPOSE: Severe asthma and asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) are difficult to control and are often associated with poor clinical outcomes. However, much is not understood regarding the diagnosis and treatment of severe asthma and ACOS. To evaluate the current perceptions of severe asthma and COPD among asthma and COPD specialists, we designed an e-mail and internet-based questionnaire survey. METHODS: Subjects were selected based on clinical specialty from among the members of the Korean Academy of Asthma, Allergy and Clinical Immunology and the Korean Academy of Tuberculosis and Respiratory Diseases...
May 2018: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/29653129/delivering-drugs-to-the-lungs-the-history-of-repurposing-in-the-treatment-of-respiratory-diseases
#3
Stephen P Newman
The repurposing of drug delivery by the pulmonary route has been applied to treatment and prophylaxis of an increasingly wide range of respiratory diseases. Repurposing has been most successful for the delivery of inhaled bronchodilators and corticosteroids in patients with asthma and chronic obstructive pulmonary disease (COPD). Repurposing utilizes the advantages that the pulmonary route offers in terms of more targeted delivery to the site of action, the use of smaller doses, and a lower incidence of side-effects...
April 11, 2018: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29601494/the-burden-of-serious-fungal-infections-in-cameroon
#4
Christine E Mandengue, David W Denning
Fungal infections are frequent in Cameroon, and invasive fungal infections are sometimes detected, usually in HIV-infected patients. For these reasons, we have estimated the burden of fungal infections. Using published literature and population estimates for the at-risk group, we used deterministic modelling to derive national incidence and prevalence estimates for the most serious fungal diseases. HIV infection is common and an estimated 120,000 have CD4 counts <200 × 10⁶/mL and commonly present with opportunistic infection...
March 30, 2018: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29562641/estimating-the-burden-of-serious-fungal-infections-in-uruguay
#5
Marina Macedo-Viñas, David W Denning
We aimed to estimate for the first time the burden of fungal infections in Uruguay. Data on population characteristics and underlying conditions were extracted from the National Statistics Institute, the World Bank, national registries, and published articles. When no data existed, risk populations were used to estimate frequencies extrapolating from the literature. Population structure (inhabitants): total 3,444,006; 73% adults; 35% women younger than 50 years. Size of populations at risk (total cases per year): HIV infected 12,000; acute myeloid leukemia 126; hematopoietic stem cell transplantation 30; solid organ transplants 134; COPD 272,006; asthma in adults 223,431; cystic fibrosis in adults 48; tuberculosis 613; lung cancer 1400...
March 18, 2018: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29494484/the-burden-of-fungal-diseases-in-romania
#6
Mihai Mareș, Valentina Ruxandra Moroti-Constantinescu, David W Denning
OBJECTIVE: To estimate for the first time the burden of fungal infections in Romania. METHODS: Data derived from the World Health Organization (WHO), National Institute of Statistics, Romanian public health agencies and non-profit health organizations, and published annual reports on local epidemiology were used in the present study. When no data were available, specific at-risk populations were used to calculate frequencies of serious fungal diseases, using previously published epidemiological parameters...
March 1, 2018: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29260309/hiv-infection-pulmonary-tuberculosis-and-copd-in-rural-uganda-a-cross-sectional-study
#7
Crystal M North, Joseph G Allen, Samson Okello, Ruth Sentongo, Bernard Kakuhikire, Edward T Ryan, Alexander C Tsai, David C Christiani, Mark J Siedner
PURPOSE: HIV is associated with chronic obstructive pulmonary disease (COPD) in high resource settings. Similar relationships are less understood in low resource settings. We aimed to estimate the association between HIV infection, tuberculosis, and COPD in rural Uganda. METHODS: The Uganda Non-communicable Diseases and Aging Cohort study observes people 40 years and older living with HIV (PLWH) on antiretroviral therapy, and population-based HIV-uninfected controls in rural Uganda...
February 2018: Lung
https://www.readbyqxmd.com/read/29238186/severe-copd-cases-from-korea-poland-and-usa-have-substantial-differences-in-respiratory-symptoms-and-other-respiratory-illnesses
#8
Woo Jin Kim, Jae-Joon Yim, Deog Kyeom Kim, Myung Goo Lee, Anne L Fuhlbrigge, Pawel Sliwinski, Iwona Hawrylkiewicz, Emily S Wan, Michael H Cho, Edwin K Silverman
Purpose: Chronic obstructive pulmonary disease (COPD), characterized by irreversible airflow obstruction, is a major cause of morbidity and mortality worldwide. However, geographic differences in the clinical characteristics of severe COPD patients have not been widely studied. Methods: We recruited a total of 828 severe COPD cases from three continents. Subjects in Poland were enrolled by the Institute of Tuberculosis and Lung Diseases in Warsaw; subjects in Korea participated at several university hospitals in Korea; and subjects in USA were enrolled at two clinics affiliated with academic medical centers...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29228947/estimating-prevalence-of-chronic-obstructive-pulmonary-disease-in-the-southern-cone-of-latin-america-how-different-spirometric-criteria-may-affect-disease-burden-and-health-policies
#9
Edgardo Sobrino, Vilma E Irazola, Laura Gutierrez, Chung-Shiuan Chen, Fernando Lanas, Matías Calandrelli, Jacqueline Ponzo, Nora Mores, Pamela Serón, Allison Lee, Jiang He, Adolfo L Rubinstein
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide. The study aimed to determine and compare the prevalence of COPD in the general population aged 45-74 years old according to fixed ratio and lower limit of normal (LLN) thresholds in four cities in the Southern Cone of Latin America. METHODS: The Pulmonary Risk in South America (PRISA) study used a 4-stage stratified sampling method to select 5814 participants from 4 cities in the Southern Cone of Latin America (Bariloche and Marcos Paz, Argentina; Temuco, Chile; and Pando-Barros Blancos, Uruguay)...
December 11, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29112181/vitamin-d-supplementation-in-respiratory-diseases-evidence-from-randomized-controlled-trials
#10
Carolien Mathyssen, Ghislaine Gayan-Ramirez, Roger Bouillon, Wim Janssens
Pulmonary diseases are one of the most important causes of morbidity and mortality. Although vitamin D is best known for its role in calcium, phosphorus, and bone homeostasis, it has gained attention in the recent years because of a wide range of extraskeletal effects, including its immunomodulatory and antibacterial potential. Vitamin D deficiency is highly prevalent in chronic pulmonary diseases such as chronic obstructive pulmonary disease (COPD), cystic fibrosis, tuberculosis, and asthma, and several clinical studies have been conducted investigating the effect of vitamin D supplementation on disease outcomes...
November 30, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29060142/classification-of-voluntary-coughs-applied-to-the-screening-of-respiratory-disease
#11
Christian Infante, Daniel B Chamberlain, Rahul Kodgule, Richard Ribon Fletcher
Pulmonary and respiratory diseases (e.g. asthma, COPD, allergies, pneumonia, tuberculosis, etc.) represent a large proportion of the global disease burden, mortality, and disability. In this context of creating automated diagnostic tools, we explore how the analysis of voluntary cough sounds may be used to screen for pulmonary disease. As a clinical study, voluntary coughs were recorded using a custom mobile phone stethoscope from 54 patients, of which 7 had COPD, 15 had asthma, 11 had allergic rhinitis, 17 had both asthma and allergic rhinitis, and four had both COPD and allergic rhinitis...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28931659/the-risk-of-mycobacterial-infections-associated-with-inhaled-corticosteroid-use
#12
Sarah K Brode, Michael A Campitelli, Jeffrey C Kwong, Hong Lu, Alex Marchand-Austin, Andrea S Gershon, Frances B Jamieson, Theodore K Marras
Inhaled corticosteroid (ICS) use is associated with an increased risk of pneumonia. This study was performed to determine if ICS use is associated with an increased risk of nontuberculous mycobacterial pulmonary disease (NTM-PD) or tuberculosis (TB).We conducted a population-based nested case-control study using linked laboratory and health administrative databases in Ontario, Canada, including adults aged ≥66 years with treated obstructive lung disease ( i.e. asthma, chronic obstructive pulmonary disease (COPD) or asthma-COPD overlap syndrome) between 2001 and 2013...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28762660/effect-of-pre-existing-respiratory-conditions-on-survival-of-lung-cancer-patients-a-nationwide-population-based-cohort-study
#13
Seri Hong, Eun-Cheol Park, Tae Hyun Kim, Jeoung A Kwon, Ki-Bong Yoo, Kyu-Tae Han, Ji Won Yoo, Sun Jung Kim
BACKGROUND: Common diseases with potential to increase the risk of death from lung cancer have so far not been studied in large populations. METHODS: We did a population-based retrospective cohort study using nationwide health insurance claims data from 2005 to 2012 in Korea including 205 403 lung cancer patients. Multivariate-adjusted hazard ratios (aHRs) of lung cancer mortality by presence, time intervals with lung cancer diagnosis and combinations of pre-existing chronic obstructive pulmonary disease (COPD), pneumonia, asthma and tuberculosis were calculated using the Cox-proportional hazards model...
August 1, 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28554925/a-cross-sectional-study-on-prevalence-of-chronic-obstructive-pulmonary-disease-copd-in-india-rationale-and-methods
#14
Prabu Rajkumar, Kamaraj Pattabi, Selvaraj Vadivoo, Arvind Bhome, Bill Brashier, Prashanta Bhattacharya, Sanjay M Mehendale
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common preventable and treatable chronic respiratory disease, which affects 210 million people globally. Global and national guidelines exist for the management of COPD. Although evidence-based, they are inadequate to address the phenotypic and genotypic heterogeneity in India. Co-existence of other chronic respiratory diseases can adversely influence the prognosis of COPD.India has a huge burden of COPD with various risk factors and comorbid conditions...
May 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28386744/impact-of-chronic-kidney-disease-among-korean-adults-with-chronic-obstructive-pulmonary-disease
#15
Min Young Kim, Sungmin Boo, Mijung Yoo, Jonghyun Lee, Na Ree Kang
PURPOSE: Chronic kidney disease (CKD) is an emerging issue in patients with chronic obstructive pulmonary disease (COPD). In COPD, loss of muscle mass is relatively common finding, and diagnosis of CKD should be based on measured or estimated GFR (Cavailles et al. Eur Respir Rev 22:454-475, 2013; Gosker et al. Am J Clin Nutr 71:1033-1047, 2000; Delanaye and Mariat Nat Rev Nephrol 9:513-522, 2013). We aimed to determine the prevalence and impact of CKD, defined by using chronic kidney disease epidemiology collaboration (CKD-EPI) equation, in COPD patients...
July 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28360458/prevalence-and-etiological-profile-of-chronic-obstructive-pulmonary-disease-in-nonsmokers
#16
Tariq Mahmood, Ravindra Kumar Singh, Surya Kant, Amitabh Das Shukla, Alok Chandra, Rajneesh Kumar Srivastava
BACKGROUND: Tobacco smoking has been recognized as the most important risk factor for chronic obstructive pulmonary disease (COPD) for a long time, but recent studies have shown that nonsmokers also contribute to a significant proportion of COPD. This study was performed to find out the proportion of nonsmoker individuals among COPD patients and to determine various etiologies in nonsmoker COPD patients. MATERIALS AND METHODS: This study was an observational cross-sectional study conducted in Department of Pulmonary Medicine, MLN Medical College, Allahabad...
March 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28268242/tuberculosis-associated-chronic-obstructive-pulmonary-disease
#17
REVIEW
Malay Sarkar, Srinivasa, Irappa Madabhavi, Kushal Kumar
OBJECTIVES: Reviewed the epidemiology, clinical characteristics, mechanisms, and treatment of tuberculosis associated chronic obstructive pulmonary disease. DATA SOURCE: We searched PubMed, EMBASE, and the CINAHL from inception to June 2016. We used the following search terms: Tuberculosis, COPD, Tuberculosis associated COPD, and so forth. All types of study were chosen. RESULTS AND CONCLUSION: Chronic obstructive pulmonary disease (COPD) and tuberculosis are significant public health problems, particularly in developing countries...
May 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28213689/serious-fungal-infections-in-egypt
#18
S M Zaki, D W Denning
We aimed to estimate the burden of serious fungal infections in Egypt, currently unknown, based on the size of the populations at risk and available epidemiological data. Data were obtained from the World Health Organization (WHO), the Joint United Nations Programme on HIV/AIDS (UNAIDS), and published reports with clearcut denominators. When no data existed, risk populations were used to estimate frequencies of fungal infections, using previously described methodology. The population of Egypt in 2011 was ∼82,500,000; 31% children, and 8% women >60 years of age...
June 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28188493/serious-fungal-infections-in-chile
#19
E Alvarez Duarte, D W Denning
The incidence and prevalence of fungal infections in Chile are unknown. Here, we have estimated the burden of serious fungal diseases from data obtained from clinical reports, WHO reports, Chilean census, OECD reports and comprehensive literature search available on PubMed and SciELO, among other scientific resources. Due the lack of official data about fungal diseases, frequencies were calculated based on the specific populations at risk. Recurrent vulvovaginal candidiasis (>4 episodes/year) is estimated to occur in 3108/100,000...
June 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28188492/serious-fungal-infections-in-portugal
#20
R Sabino, C Verissímo, J Brandão, C Martins, D Alves, C Pais, D W Denning
There is a lack of knowledge on the epidemiology of fungal infections worldwide because there are no reporting obligations. The aim of this study was to estimate the burden of fungal disease in Portugal as part of a global fungal burden project. Most published epidemiology papers reporting fungal infection rates from Portugal were identified. Where no data existed, specific populations at risk and fungal infection frequencies in those populations were used in order to estimate national incidence or prevalence, depending on the condition...
July 2017: European Journal of Clinical Microbiology & Infectious Diseases
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