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https://www.readbyqxmd.com/read/27814579/the-emergence-of-aspergillus-species-in-chronic-respiratory-disease
#1
Anthony Ca Yii, Mariko S Koh, Therese S Lapperre, Gan L Tan, Sanjay H Chotirmall
Chronic lung disease is recognized as an important risk factor for developing pulmonary aspergillosis. The development of specific aspergillus-associated syndromes depends on host immunity and underlying lung disease. In the setting of asthma, hypersensitivity to Aspergillus can lead to allergic bronchopulmonary aspergillosis (ABPA) or severe asthma with fungal sensitization (SAFS). Chronic use of systemic or inhaled corticosteroids coupled with recurrent antibiotic use for exacerbations prevalent in chronic obstructive pulmonary disease (COPD) predisposes to chronic pulmonary aspergillosis (CPA)...
January 1, 2017: Frontiers in Bioscience (Scholar Edition)
https://www.readbyqxmd.com/read/27806533/epidemiologic-correlates-of-chronic-respiratory-infections-in-adults-an-urban-slum-of-bhubaneswar-odisha-india
#2
Sonali Kar, Ipsa Mohapatra, Amrita Konar
INTRODUCTION: Urbanization is marked by emergence of slum areas, wherein migrants from the nearby villages stay in temporary establishments for seeking avenues of employment. These dwellings lack most of the essential living conditions like safe water, healthy living conditions and access to health services. This population is also vulnerable to social evils like alcohol and tobacco addiction. KIMS, a medical college in Bhubaneswar, Odisha, India has an Urban Health Training Centre (UHTC) that caters to a slum population of nearly 12,000 population for their primary health needs...
August 4, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27787715/bifunctional-drugs-for-the-treatment-of-respiratory-diseases
#3
Clive Page, Mario Cazzola
Over the last decade, there has been a steady increase in the use of fixed dose combinations for the treatment of a range of diseases, including cancer, AIDS, tuberculosis and other infectious diseases. It is now evident that patients with asthma or chronic obstructive pulmonary disease (COPD) can also benefit from the use of fixed dose combinations, including combinations of a long-acting β2-agonist (LABA) and an inhaled corticosteroid (ICS), and combinations of LABAs and long-acting muscarinic receptor antagonists (LAMAs)...
October 28, 2016: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/27725053/primary-care-physicians-ability-to-diagnose-the-most-prevalent-respiratory-diseases
#4
B P de São José, P A M Camargos, E D Bateman, C M A Botelho, J G F de Seixas Maciel, E V Mancuzo, R de Amorim Corrêa
BACKGROUND: There are few reports on the ability of primary care physicians (PCPs) to diagnose acute and chronic respiratory diseases. We assessed the agreement between PCPs and pulmonologists in diagnosing pulmonary tuberculosis (TB), chronic obstructive pulmonary disease (COPD), asthma and acute respiratory infections (ARI). SETTING: Metropolitan Region of Belo Horizonte, State of Minas Gerais, Brazil. METHODS: PCPs filled out a symptom-based questionnaire for adult patients presenting with respiratory symptoms...
October 2016: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/27448309/asthma-chronic-obstructive-pulmonary-diseases-overlap-syndrome-increases-the-risk-of-incident-tuberculosis-a-national-cohort-study
#5
Jun-Jun Yeh, Yu-Chiao Wang, Chia-Hung Kao
PURPOSE: The association between asthma-chronic obstructive pulmonary diseases (COPD) overlap syndrome (ACOS) and tuberculosis (TB) has yet to be studied. METHODS: The newly diagnosed TB patients (age > 20 y) treated from January 2000 to December 2008 were included (ACOS cohort, n = 10 751; non-ACOS cohort, n = 42 966). The non-ACOS cohort involved patients with confirmed absence of ACOS. We calculated incidence rate ratios (IRRs) for TB in the ACOS and non-ACOS cohorts by using poisson regression analysis...
2016: PloS One
https://www.readbyqxmd.com/read/27336790/phenotyping-adults-with-non-cystic-fibrosis-bronchiectasis-a-10-year-cohort-study-in-a-french-regional-university-hospital-center
#6
Matthieu Buscot, Héloïse Pottier, Charles-Hugo Marquette, Sylvie Leroy
BACKGROUND: Data concerning phenotypes in bronchiectasis are scarce. OBJECTIVE: The aim of this study was to describe the clinical, functional and microbiological phenotypes of patients with bronchiectasis. METHODS: A monocentric retrospective study in a university hospital in France was conducted over 10 years (2002-2012). Non-cystic fibrosis patients with tomographic confirmation of bronchiectasis were included. The clinical, functional and microbiological data of patients were analyzed relying on the underlying etiology...
2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27152607/allergic-bronchopulmonary-aspergillosis-complicating-swyer-james-macleod-s-syndrome-case-report-and-review-of-literature
#7
I S Sehgal, S Dhooria, D Behera, R Agarwal
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder that results from immune responses mounted against antigens of Aspergillus fumigatus, resulting in non-specific respiratory symptoms and structural lung damage. Classically defined in individuals suffering from bronchial asthma and cystic fibrosis, ABPA has recently been described in other lung diseases including COPD, pulmonary tuberculosis, idiopathic bronchiectasis and others. Herein, we report the first case of ABPA complicating Swyer-James-Macleod's syndrome that was successfully treated with oral antifungal therapy...
May 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27102185/smokehaz-systematic-reviews-and-meta-analyses-of-the-effects-of-smoking-on-respiratory-health
#8
Leah Jayes, Patricia L Haslam, Christina G Gratziou, Pippa Powell, John Britton, Constantine Vardavas, Carlos Jimenez-Ruiz, Jo Leonardi-Bee
BACKGROUND: Smoking tobacco increases the risk of respiratory disease in adults and children, but communicating the magnitude of these effects in a scientific manner that is accessible and usable by the public and policymakers presents a challenge. We have therefore summarized scientific data on the impact of smoking on respiratory diseases to provide the content for a unique resource, SmokeHaz. METHODS: We conducted systematic reviews and meta-analyses of longitudinal studies (published to 2013) identified from electronic databases, gray literature, and experts...
July 2016: Chest
https://www.readbyqxmd.com/read/27038474/the-risk-factors-and-characteristics-of-copd-among-nonsmokers-in-korea-an-analysis-of-knhanes-iv-and-v
#9
Su Hwan Lee, Eu Dong Hwang, Ju Eun Lim, Sungwoo Moon, Young Ae Kang, Ji Ye Jung, Moo Suk Park, Se Kyu Kim, Joon Chang, Young Sam Kim, Song Yee Kim
PURPOSE: Chronic obstructive pulmonary disease (COPD) is increasing in prevalence and mortality. This study evaluated the prevalence, risk factors, characteristics, and health-related quality of life (HRQoL) of COPD among nonsmokers in Korea. METHODS: This was a population-based cross-sectional study using data obtained from the Fourth and Fifth Korean National Health and Nutrition Examination Survey, which was conducted from 2007 to 2011. RESULTS: A total of 15,063 participants completely answered the questionnaire and performed the spirometry...
June 2016: Lung
https://www.readbyqxmd.com/read/26985430/a-review-of-vitamin-d-effects-on-common-respiratory-diseases-asthma-chronic-obstructive-pulmonary-disease-and-tuberculosis
#10
REVIEW
Mohammad Esmaeil Hejazi, Faezeh Modarresi-Ghazani, Taher Entezari-Maleki
Despite the classic role of Vitamin D in skeletal health, new aspects of Vitamin D have been discovered in tissues and organs other than bones. Epidemiological and observational studies demonstrate a link between Vitamin D deficiency and risk of developing respiratory diseases including asthma, chronic obstructive pulmonary disease (COPD), and tuberculosis (TB). To review the literature, we searched the terms "Vitamin D" (using the set operator) and "asthma," "COPD" and "TB" in electronic databases, including PubMed/MEDLINE, Scopus, and Google Scholar until July 2015...
January 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/26962806/pre-existing-pulmonary-diseases-and-survival-in-patients-with-stage-dependent-lung-adenocarcinoma-a-strobe-compliant-article
#11
Zhi-Hong Jian, Jing-Yang Huang, Oswald Ndi Nfor, Kai-Ming Jhang, Wen-Yuan Ku, Chien-Chang Ho, Chia-Chi Lung, Hui-Hsien Pan, Yu-Chiu Liang, Ming-Fang Wu, Yung-Po Liaw
Asthma, chronic obstructive pulmonary disease (COPD), and pulmonary tuberculosis (TB) are common lung diseases associated with lung cancer mortality. This study evaluated sex disparities in pre-existing pulmonary diseases and stage-dependent lung adenocarcinoma survival.Patients newly diagnosed with lung adenocarcinoma between 2003 and 2008 were identified using the National Health Insurance Research Database and Cancer Registry. Cases with lung adenocarcinoma were followed until the end of 2010. Survival curves were estimated by the Kaplan-Meier method...
March 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26950245/common-polymorphisms-in-il-27-genes-may-contribute-to-risk-of-various-human-diseases-in-asian-populations-a-meta-analysis
#12
Yun-Feng Zhang, An-Di Zhao
BACKGROUND: Genetic variations in the IL-27 gene have been proven to be associated with various types of human cancers and diseases. The purpose of the current study was to clarify the associations of the IL-27 rs153109 A>G and rs181206 T>C variants with human diseases using a meta-analysis study. MATERIAL/METHODS: A comprehensive electronic and manual search was carried out to find potential eligible studies. The effect size was represented by the unadjusted odds ratios (ORs)...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/26864653/radiomics-based-differentiation-of-lung-disease-models-generated-by-polluted-air-based-on-x-ray-computed-tomography-data
#13
Krisztián Szigeti, Tibor Szabó, Csaba Korom, Ilona Czibak, Ildikó Horváth, Dániel S Veres, Zoltán Gyöngyi, Kinga Karlinger, Ralf Bergmann, Márta Pócsik, Ferenc Budán, Domokos Máthé
BACKGROUND: Lung diseases (resulting from air pollution) require a widely accessible method for risk estimation and early diagnosis to ensure proper and responsive treatment. Radiomics-based fractal dimension analysis of X-ray computed tomography attenuation patterns in chest voxels of mice exposed to different air polluting agents was performed to model early stages of disease and establish differential diagnosis. METHODS: To model different types of air pollution, BALBc/ByJ mouse groups were exposed to cigarette smoke combined with ozone, sulphur dioxide gas and a control group was established...
February 11, 2016: BMC Medical Imaging
https://www.readbyqxmd.com/read/26636168/chronic-obstructive-pulmonary-disease-diagnosis-and-classification-of-severity
#14
REVIEW
P J Viviers, R N van Zyl-Smit
Chronic obstructive pulmonary disease (COPD) is a common, progressive and preventable non-communicable respiratory disorder. It is often confused with asthma and poorly understood by many lay people. The primary cause of COPD is tobacco smoking, but in the South African (SA) context, biomass fuel exposure/household pollution, tuberculosis, HIV and mining exposure are additional important causes.There is a very high prevalence of COPD in SA and it is the third leading cause of mortality globally.The diagnosis of COPD is based predominantly on symptoms, i...
September 2015: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/26578109/strengthening-the-delivery-of-asthma-and-chronic-obstructive-pulmonary-disease-care-at-primary-health-care-facilities-study-design-of-a-cluster-randomized-controlled-trial-in-pakistan
#15
RANDOMIZED CONTROLLED TRIAL
Muhammad Amir Khan, Maqsood Ahmed, Shirin Anil, John Walley
BACKGROUND: Respiratory diseases, namely asthma and chronic obstructive pulmonary disease (COPD), account for one-fourth of the patients at the primary health-care (PHC) facilities in Pakistan. Standard care practices to manage these diseases are necessary to reduce the morbidity and mortality rate associated with non-communicable diseases in developing countries. OBJECTIVE: To develop and measure the effectiveness of operational guidelines and implementation materials, with sound scientific evidence, for expanding lung health care, especially asthma and COPD through PHC facilities already strengthened for tuberculosis (TB) care in Pakistan...
2015: Global Health Action
https://www.readbyqxmd.com/read/26526071/the-effects-of-pulmonary-diseases-on-histologic-types-of-lung-cancer-in-both-sexes-a-population-based-study-in-taiwan
#16
Jing-Yang Huang, Zhi-Hong Jian, Oswald Ndi Nfor, Wen-Yuan Ku, Pei-Chieh Ko, Chia-Chi Lung, Chien-Chang Ho, Hui-Hsien Pan, Chieh-Ying Huang, Yu-Chiu Liang, Yung-Po Liaw
BACKGROUND: The associations between pulmonary diseases (asthma, chronic obstructive pulmonary disease [COPD], and tuberculosis [TB]) and subsequent lung cancer risk have been reported, but few studies have investigated the association with different histologic types of lung cancer. METHODS: Patients newly diagnosed with lung cancer from 2004 to 2008 were identified from the National Health Insurance Research Database in Taiwan. Histologic types of lung cancer were further confirmed using the Taiwan Cancer Registry Database...
2015: BMC Cancer
https://www.readbyqxmd.com/read/26508848/effect-of-tiotropium-on-lung-function-decline-in-early-stage-of-chronic-obstructive-pulmonary-disease-patients-propensity-score-matched-analysis-of-real-world-data
#17
Ha Youn Lee, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Chang-Hoon Lee, Deog Kyeom Kim, Sang-Min Lee, Ho Il Yoon, Jae-Joon Yim, Young Whan Kim, Sung Koo Han, Chul-Gyu Yoo
BACKGROUND: Tiotropium failed to slow the annual rate of forced expiratory volume in 1 second (FEV1) decline in chronic obstructive pulmonary disease (COPD) patients with <70% predicted FEV1. However, the rate of FEV1 decline is known to be faster at early stages, which suggests that the effects of tiotropium may be more prominent in early-stage of COPD patients. The aim of this study was to test the hypothesis that tiotropium modifies the rate of FEV1 decline in COPD patients with an FEV1≥70%...
2015: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/26451840/chronic-airflow-obstruction-in-a-black-african-population-results-of-bold-study-ile-ife-nigeria
#18
Daniel O Obaseki, Gregory E Erhabor, Louisa Gnatiuc, Olufemi O Adewole, Sonia A Buist, Peter G Burney
Global estimates suggest that Chronic Obstructive Pulmonary Disease (COPD) is emerging as a leading cause of death in developing countries but there are few spirometry-based general population data on its prevalence and risk factors in sub-Saharan Africa. We used the Burden of Obstructive Lung Disease (BOLD) protocol to select a representative sample of adults aged 40 years and above in Ile-Ife, Nigeria. All the participants underwent spirometry and provided information on smoking history, biomass and occupational exposures as well as diagnosed respiratory diseases and symptoms...
2016: COPD
https://www.readbyqxmd.com/read/26449513/burden-of-serious-fungal-infections-in-ukraine
#19
Ali Osmanov, David W Denning
Ukraine has high rates of TB, AIDS and cancer. We estimated the burden of fungal disease from epidemiology papers and specific populations at risk and fungal infection frequencies. HIV/AIDS cases and deaths (2012) and tuberculosis statistics were obtained from the State Service of Ukraine, while chronic obstructive pulmonary disease (COPD) cases were from M. Miravitlles et al., Thorax 64, 863-868 (2009). Annual estimates are 893,579 Ukrainian women get recurrent vaginal thrush (≥4× per year), 50,847 cases of oral candidiasis and 13,727 cases of oesophageal candidiasis in HIV, and 101 (1%) of 10,085 new AIDS cases develop cryptococcal meningitis, 6152 cases of Pneumocystis pneumonia (13...
October 2015: Mycoses
https://www.readbyqxmd.com/read/26250371/allergic-bronchopulmonary-aspergillosis-in-an-adult-with-kartagener-syndrome
#20
REVIEW
Inderpaul Singh Sehgal, Sahajal Dhooria, Amanjit Bal, Ritesh Agarwal
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder resulting from immune responses directed against inhaled Aspergillus fumigatus antigens. It manifests with poorly controlled asthma, fleeting pulmonary opacities and structural lung damage in the form of bronchiectasis. Initially defined in individuals suffering from bronchial asthma and cystic fibrosis, it has also been described in patients with other structural lung disorders such as chronic obstructive pulmonary disease, pulmonary tuberculosis, idiopathic bronchiectasis and others...
August 6, 2015: BMJ Case Reports
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