keyword
https://read.qxmd.com/read/38635076/state-of-open-science-in-cancer-research
#1
JOURNAL ARTICLE
Cristina Rius, Yiming Liu, Andrea Sixto-Costoya, Juan Carlos Valderrama-Zurián, Rut Lucas-Dominguez
PURPOSE: This study has been focused on assessing the Open Science scenario of cancer research during the period 2011-2021, in terms of the derived scientific publications and raw data dissemination. METHODS: A cancer search equation was executed in the Science Citation Index-Expanded, collecting the papers signed by at least one Spanish institution. The same search strategy was performed in the Data Citation Index to describe dataset diffusion. RESULTS: 50,822 papers were recovered, 71% of which belong to first and second quartile journals...
April 18, 2024: Clinical & Translational Oncology
https://read.qxmd.com/read/38632695/significant-healthcare-resource-utilisation-in-the-management-of-skin-and-soft-tissue-infections-in-the-torres-strait-australia
#2
JOURNAL ARTICLE
Haylee Fox, Allison Hempenstall, Pelista Pilot, Emily Callander, Simon Smith, Malcolm I McDonald, Josh Hanson
INTRODUCTION: Aboriginal and Torres Strait Islander Peoples (First Nations Australians) living in remote communities are hospitalised with skin and soft tissue infections (SSTIs) at three times the rate of non-First Nations Australians. The Torres Strait in tropical northern Australia has a highly dispersed population mainly comprising First Nations Australians. This study aimed to define the health service utilisation and health system costs associated with SSTIs in the Torres Strait and to improve the quality of regional healthcare delivery...
April 2024: Rural and Remote Health
https://read.qxmd.com/read/38632118/impact-of-operative-time-on-textbook-outcome-after-minimally-invasive-esophagectomy-a-risk-adjusted-analysis-from-a-high-volume-center
#3
JOURNAL ARTICLE
Yuxin Yang, Chao Jiang, Zhichao Liu, Kaiyuan Zhu, Boyao Yu, Chang Yuan, Cong Qi, Zhigang Li
BACKGROUND: We aimed to study the impact of operative time on textbook outcome (TO), especially postoperative complications and length of postoperative stay in minimally invasive esophagectomy. METHODS: Patients undergoing esophagectomy for curative intent within a prospectively maintained database from 2016 to 2022 were retrieved. Relationships between operative time and outcomes were quantified using multivariable mixed-effects models with medical teams random effects...
April 17, 2024: Surgical Endoscopy
https://read.qxmd.com/read/38631380/identifying-barriers-to-the-implementation-of-communicating-narrative-concerns-entered-by-registered-nurses-an-early-warning-system-smartapp
#4
JOURNAL ARTICLE
Mollie Hobensack, Jennifer Withall, Brian Douthit, Kenrick Cato, Patricia Dykes, Sandy Cho, Graham Lowenthal, Catherine Ivory, Po-Yin Yen, Sarah Rossetti
BACKGROUND:  Nurses are at the frontline of detecting patient deterioration. We developed Communicating Narrative Concerns Entered by Registered Nurses (CONCERN), an early warning system for clinical deterioration that generates a risk prediction score utilizing nursing data. CONCERN was implemented as a randomized clinical trial at two health systems in the Northeastern United States. Following the implementation of CONCERN, our team sought to develop the CONCERN Implementation Toolkit to enable other hospital systems to adopt CONCERN...
March 2024: Applied Clinical Informatics
https://read.qxmd.com/read/38627056/tele-icu-enabled-management-of-an-organ-donor-in-an-under-resourced-setting
#5
JOURNAL ARTICLE
Prudhvi Dasari, Maheeja Reddy, Dileep Singh Parmar, Carl Britto
A man in his 30s was involved in a road traffic crash in a small town in India, not equipped to deal with cases of brainstem death. He was declared brain-dead after a few hours. The patient's information was forwarded to organ specialists across the country, with the goal of preserving the patient's organs for donation via a tele-ICU model. The team comprising bedside doctors and remote intensivists communicating via an indigenously developed tele-ICU platform managed the patient for 24 hours, following treatment protocols and providing critical care to ensure that the patient's vital organs were optimally perfused...
April 16, 2024: BMJ Case Reports
https://read.qxmd.com/read/38623396/global-health-commodities-supply-chain-in-the-era-of-covid-19-pandemic-challenges-impacts-and-prospects-a-systematic-review
#6
REVIEW
Zelalem Tilahun Mekonen, Teferi Gedif Fenta, Simon Peter Nadeem, Denny J Cho
BACKGROUND: The COVID-19 pandemic led to the most substantial health crisis in the 21st Century. This pandemic interrupted the supply of essential commodities for human beings. Among the essential commodities for human survival, disruption of the supply of essential health commodities has become a global concern. OBJECTIVE: The study aimed to systematically analyze published articles on the challenges, impacts, and prospects of the global health commodities' supply chain in the era of the COVID-19 pandemic...
2024: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/38607438/vein-of-galen-aneurysmal-malformation-does-size-affect-outcome
#7
JOURNAL ARTICLE
Costanza Parodi, Margherita Aluffi Valletti, Domenico Tortora, Silvia Buratti, Marisa Mallamaci, Giulia Tuo, Angela Pistorio, Andrea Moscatelli, Andrea Rossi, Mariasavina Severino
PURPOSE: To validate a semiautomated method for segmenting vein of Galen aneurysmal malformations (VGAM) and to assess the relationship between VGAM volume and other angioarchitectural features, cardiological findings, and outcomes. METHODS: In this retrospective study, we selected all subjects with VGAM admitted to the Gaslini Children's Hospital between 2009 and 2022. Clinical data were retrieved from electronic charts. We compared 3D-Slicer segmented VGAM volumes obtained by two independent observers using phase-contrast MR venography to those obtained with manual measurements performed on T2-weighted images...
April 12, 2024: Neuroradiology
https://read.qxmd.com/read/38599619/provider-perceptions-of-an-electronic-health-record-prostate-cancer-screening-tool
#8
JOURNAL ARTICLE
Sigrid V Carlsson, Mark Preston, Andrew Vickers, Deepak Malhotra, Behfar Ehdaie, Michael Healey, Adam S Kibel
OBJECTIVES:  We conducted a focus group to assess the attitudes of primary care physicians (PCPs) toward prostate-specific antigen (PSA)-screening algorithms, perceptions of using decision support tools, and features that would make such tools feasible to implement. METHODS:  A multidisciplinary team (primary care, urology, behavioral sciences, bioinformatics) developed the decision support tool that was presented to a focus group of 10 PCPs who also filled out a survey...
March 2024: Applied Clinical Informatics
https://read.qxmd.com/read/38585349/toast-stroke-subtype-classification-in-clinical-practice-implications-for-the-get-with-the-guidelines-stroke-nationwide-registry
#9
JOURNAL ARTICLE
Cecelia M Rathburn, Katherine T Mun, Latisha K Sharma, Jeffrey L Saver
INTRODUCTION: The TOAST (Trial of ORG 10172 in Acute Stroke Treatment) is the most commonly used ischemic stroke subtype classification system worldwide and a required field in the US National Get With The Guidelines-Stroke (GWTG-Stroke) registry. However, stroke diagnostics have advanced substantially since the TOAST classification was designed 30 years ago, potentially making it difficult to apply reliably. METHODS: In this prospective diagnostic accuracy study, we analyzed consecutive ischemic stroke patients admitted to a Comprehensive Stroke Center between July-October 2021...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38585252/indications-for-dental-specialists-for-treating-obstructive-sleep-apnea-with-mandibular-advancement-devices-a-narrative-review
#10
REVIEW
Antonino Lo Giudice, Salvatore La Rosa, Vincenzo Ronsivalle, Gaetano Isola, Marco Cicciù, Giulio Alessandri-Bonetti, Rosalia Leonardi
Obstructive sleep apnea (OSA) syndrome is characterized by repeated airway collapse during sleep. It determines cardiovascular, pulmonary, and neurocognitive consequences and is associated with several daytime and nighttime symptoms that influence the patient's quality of life. The contribution of the dental specialist in the clinical management of OSA patients entails participating in the screening process as diagnostic sentinels and providing adequate treatment using mandibular advancement devices (MADs)...
2024: International Journal of Dentistry
https://read.qxmd.com/read/38572844/nurses-practices-in-stroke-related-dysphagia-in-low-and-middle-income-countries
#11
JOURNAL ARTICLE
Kirsten Rowe, Maria N Du Toit, Sarveshvari B Pillay, Esedra Krüger
BACKGROUND:  Nurses are often required to perform dysphagia screening prior to oral intake by people following stroke. Previous studies report limited knowledge of nurses in identifying symptoms of post-stroke dysphagia. OBJECTIVE:  To explore existing literature regarding nurses' practices and knowledge in the identification and management of post-stroke oropharyngeal dysphagia (OPD) in low- and middle income countries (LMICs). METHOD:  A scoping review was conducted according to the PRISMA-ScR guidelines...
March 28, 2024: Curationis
https://read.qxmd.com/read/38570233/point-of-care-device-for-the-noninvasive-assessment-of-hepatic-macrosteatosis-in-liver-donors
#12
JOURNAL ARTICLE
Allwyn S Rajamani, Ashwin Rammohan, Kuzhandai Shamlee J, Abdul R Hakeem, V V Raghavendra Sai, Mukul Vij, Mohamed Rela
BACKGROUND: Quantification of macrosteatosis (MS) in the liver is important given that it has shown to directly correlate with adverse post-liver transplant (LT) outcomes. With advances in medical technology and an implicit understanding of pathology, noninvasive methods of quantitatively assessing MS are in various stages of development. Each of these methods is based on the physical principles of differences between a fat-laden hepatocyte and a normal one. METHODS: In this regard, after a proof-of-concept study on a prototype for a simple, real-time, handheld device using the principle of diffuse reflectance spectroscopy, this study presents an upgraded point-of-care (POC) device for the noninvasive assessment of hepatic MS in liver donors...
February 29, 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38566118/-nowhere-and-no-one-is-safe-spatial-analysis-of-damage-to-critical-civilian-infrastructure-in-the-gaza-strip-during-the-first-phase-of-the-israeli-military-campaign-7-october-to-22-november-2023
#13
JOURNAL ARTICLE
Yara Asi, David Mills, P Gregg Greenough, Dennis Kunichoff, Saira Khan, Jamon Van Den Hoek, Corey Scher, Saleem Halabi, Sawsan Abdulrahim, Nadine Bahour, A Kayum Ahmed, Bram Wispelwey, Weeam Hammoudeh
BACKGROUND: Since the Hamas attacks in Israel on 7 October 2023, the Israeli military has launched an assault in the Gaza Strip, which included over 12,000 targets struck and over 25,000 tons of incendiary munitions used by 2 November 2023. The objectives of this study include: (1) the descriptive and inferential spatial analysis of damage to critical civilian infrastructure (health, education, and water facilities) across the Gaza Strip during the first phase of the military campaign, defined as 7 October to 22 November 2023 and (2) the analysis of damage clustering around critical civilian infrastructure to explore broader questions about Israel's adherence to International Humanitarian Law (IHL)...
April 2, 2024: Conflict and Health
https://read.qxmd.com/read/38561472/correlation-of-glycolysis-immune-related-genes-in-the-follicular-microenvironment-of-endometriosis-patients-with-art-outcomes
#14
JOURNAL ARTICLE
Shana Guo, Qizhen Chen, Jiaqi Liang, Huanmei Wu, Li Li, Yanqiu Wang
Endometriosis (EMT) -related infertility has been a challenge for clinical research. Many studies have confirmed that abnormal alterations in the immune microenvironment and glycolysis are instrumental in causing EMT-related infertility. Recently, our research team identified several key glycolysis-immune-related genes in the endometrial cells of EMT patients. This study aimed to further investigate the expression patterns of pyruvate dehydrogenase kinase 3 (PDK3), glypican-3 (GPC3), and alcohol dehydrogenase 6 (ADH6), which are related to glycolysis and immunity, in the follicular microenvironment of infertile patients with EMT using enzyme-linked immunosorbent assay (ELISA) and quantitative real-time polymerase chain reaction (qRT-PCR) assays...
April 1, 2024: Reproductive Sciences
https://read.qxmd.com/read/38560485/an-integrative-systematic-review-of-promoting-patient-safety-within-prehospital-emergency-medical-services-by-paramedics-a-role-theory-perspective
#15
REVIEW
Maria Strandås, M Flores Vizcaya-Moreno, Kari Ingstad, Jaana Sepp, Ljudmila Linnik, Mojtaba Vaismoradi
Timely and effective prehospital care significantly impacts patient outcomes. Paramedics, as the frontline providers of emergency medical services, are entrusted with a range of critical responsibilities aimed at safeguarding the well-being of patients from the moment they initiate contact in the out-of-hospital environment to the time of handover at healthcare facilities. This study aimed to understand the multifaceted roles of paramedics in promoting patient safety within the context of prehospital emergency medical services...
2024: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/38557155/exploring-the-inclusion-of-person-centered-care-domains-in-stroke-transitions-of-care-interventions-a-scientific-statement-from-the-american-heart-association
#16
REVIEW
Michelle L A Nelson, Evan MacEachern, Janet Prvu Bettger, Michelle Camicia, James J García, Moira K Kapral, Claranne Mathiesen, Jill I Cameron
BACKGROUND: Health care teams along the stroke recovery continuum have a responsibility to support care transitions and return to the community. Ideally, individualized care will consider patient and family preferences, best available evidence, and health care professional input. Person-centered care can improve patient-practitioner interactions through shared decision-making in which health professionals and institutions are sensitive to those for whom they provide care. However, it is unclear how the concepts of person-centered care have been described in reports of stroke transitional care interventions...
April 1, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38554567/nursing-students-experiences-with-test-enhanced-learning-in-teams-a-cross-sectional-study
#17
JOURNAL ARTICLE
Marianne Synnes Emblemsvåg
BACKGROUND: Many nursing students struggle with the disciplines of biosciences, particularly Anatomy, physiology, and biochemistry, which are introduced in the first year. Nursing students' motivation, prior knowledge, and academic performance matter, but teaching methods may also influence students' learning process. Retrieving knowledge through testing has previously proven to enhance learning to a greater extent than time spent on other classroom activities. OBJECTIVE: The aim of this study was to explore nursing students' experiences with test-enhanced learning as a way of enhancing learning in Anatomy, physiology, and biochemistry...
March 27, 2024: Nurse Education Today
https://read.qxmd.com/read/38549934/the-global-landscape-and-research-trend-of-lymphangiogenesis-in-breast-cancer-a-bibliometric-analysis-and-visualization
#18
REVIEW
Liuyan Xu, Xuan Wang, Beibei Wang, Bingxin Meng, Xiaohua Pei
BACKGROUND: Breast cancer persists as a major public health issue on a global scale. Lymphangiogenesis is an indispensable element in the promotion of breast cancer metastasis. Inhibiting the metastasis of breast cancer can be accomplished through targeting lymphangiogenesis. The purpose of this study was to examine research trends, major topics, and development directions of lymphangiogenesis in breast cancer through a bibliometric analysis, which may serve as a reference for future research and clinical practice...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38541994/haemophilia-and-cancer-a-literature-review
#19
REVIEW
Ezio Zanon, Annamaria Porreca, Paolo Simioni
BACKGROUND: Opinions in the literature on the impact of cancer on patients with haemophilia are contradictory. There is a lack of data on the clinical presentation and management of cancer in patients with haemophilia (PWH). METHODS: Papers were found following a comprehensive search in PubMed, Google Scholar, and Scopus using the terms "cancer" and "haemophilia" without time limits and using the English language as a filter. The references from all the retrieved original articles and reviews were assessed for additional relevant articles...
March 19, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38517387/identification-and-validation-of-a-novel-signature-based-on-macrophage-marker-genes-for-predicting-prognosis-and-drug-response-in-kidney-renal-clear-cell-carcinoma-by-integrated-analysis-of-single-cell-and-bulk-rna-sequencing
#20
JOURNAL ARTICLE
Xiaoxu Chen, Zheyu Zhang, Zheng Qin, Xiao Zhu, Kaibin Wang, Lijuan Kang, Changying Li, Haitao Wang
Macrophages are found in a variety of tumors and play a critical role in shaping the tumor microenvironment, affecting tumor progression, metastasis, and drug resistance. However, the clinical relevance of marker genes associated with macrophage in kidney renal clear cell carcinoma (KIRC) has yet to be documented. In this study, we initiated a thorough examination of single-cell RNA sequencing (scRNA-seq) data for KIRC retrieved from the Gene Expression Omnibus (GEO) database and determined 244 macrophage marker genes (MMGs)...
March 20, 2024: Aging
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