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https://www.readbyqxmd.com/read/29340495/validation-of-the-stop-bang-questionnaire-as-a-means-of-screening-for-obstructive-sleep-apnea-in-adults-in-brazil
#1
Ricardo Luiz de Menezes Duarte, Lorena Barbosa de Moraes Fonseca, Flavio José Magalhães-da-Silveira, Erika Aparecida da Silveira, Marcelo Fouad Rabahi
OBJECTIVE: To validate the Portuguese-language version of the STOP-Bang (acronym for Snoring, Tiredness, Observed apnea, high blood Pressure, Body mass index, Age, Neck circumference, and Gender) questionnaire, culturally adapted for use in Brazil, as a means of screening for obstructive sleep apnea (OSA) in adults. METHODS: In this validation study, we enrolled patients ≥ 18 years of age, recruited between May of 2015 and November of 2016. All patients completed the STOP-Bang questionnaire and underwent overnight polysomnography...
November 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29335346/severity-of-sacroiliitis-and-erythrocyte-sedimentation-rate-are-associated-with-a-low-trabecular-bone-score-in-young-male-patients-with-ankylosing-spondylitis
#2
Kwi Young Kang, Min Kyung Chung, Ha Neul Kim, Yeon Sik Hong, Ji Hyeon Ju, Sung-Hwan Park
OBJECTIVE: To examine factors related to a low trabecular bone score (TBS) and the association between TBS and vertebral fractures in patients with ankylosing spondylitis (AS). METHODS: One hundred patients (all male, aged < 50 yrs) who fulfilled the modified New York criteria for the classification of AS were enrolled. The TBS and bone mineral density (BMD) were assessed using dual-energy X-ray absorptiometry. Clinical variables, inflammatory markers, and the presence of vertebral fractures were also assessed...
January 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29329660/cochlea-ct-radiomics-predicts-chemoradiotherapy-induced-sensorineural-hearing-loss-in-head-and-neck-cancer-patients-a-machine-learning-and-multi-variable-modelling-study
#3
Hamid Abdollahi, Shayan Mostafaei, Susan Cheraghi, Isaac Shiri, Seied Rabi Mahdavi, Anoshirvan Kazemnejad
OBJECTIVES: Immediately or after head-and-neck (H&N) cancer chemoradiotherapy (CRT), patients may undergone significant sensorineural hearing loss (SNHL) which could affect their quality of life. Radiomic feature analysis is proposed to predict SNHL induced by CRT. MATERIAL AND METHODS: 490 image features of 94 cochlea from 47 patients treated with three dimensional conformal RT (3DCRT) for different H&N cancers were extracted from CT images. Different machine learning (ML) algorithms and also least absolute shrinkage and selection operator (LASSO) penalized logistic regression were implemented on radiomic features for feature selection, classification and prediction...
January 9, 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29323235/the-value-of-narrow-band-imaging-in-diagnosis-of-head-and-neck-cancer-a-meta-analysis
#4
Hui Zhou, Jing Zhang, Linghong Guo, Ji Nie, Chenjing Zhu, Xuelei Ma
Head and neck cancer is difficult to diagnose early. We aimed to estimate the diagnosis value of narrow band imaging(NBI) in head and neck cancers. We identified relevant studies through a search of PubMed, Embase and the Cochrane Library. We used a random effect model. Subgroup analysis and meta-regression analysis were performed to estimate the factors which may influence the sensitivity and specificity of the NBI. We included 25 studies with total 6187 lesions. The pooled sensitivity, specificity, positive likelihood rate, negative likelihood rate and diagnostic odds ratios of NBI were 88...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29289589/few-promising-multivariable-prognostic-models-exist-for-recovery-of-people-with-non-specific-neck-pain-in-musculoskeletal-primary-care-a-systematic-review
#5
Roel W Wingbermühle, Emiel van Trijffel, Paul M Nelissen, Bart Koes, Arianne P Verhagen
QUESTION: Which multivariable prognostic model(s) for recovery in people with neck pain can be used in primary care? DESIGN: Systematic review of studies evaluating multivariable prognostic models. PARTICIPANTS: People with non-specific neck pain presenting at primary care. DETERMINANTS: Baseline characteristics of the participants. OUTCOME MEASURES: Recovery measured as pain reduction, reduced disability, or perceived recovery at short-term and long-term follow-up...
December 27, 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/29286431/pulling-membrane-nanotubes-from-giant-unilamellar-vesicles
#6
Coline Prévost, Feng-Ching Tsai, Patricia Bassereau, Mijo Simunovic
The reshaping of the cell membrane is an integral part of many cellular phenomena, such as endocytosis, trafficking, the formation of filopodia, etc. Many different proteins associate with curved membranes because of their ability to sense or induce membrane curvature. Typically, these processes involve a multitude of proteins making them too complex to study quantitatively in the cell. We describe a protocol to reconstitute a curved membrane in vitro, mimicking a curved cellular structure, such as the endocytic neck...
December 7, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29285438/neck-circumference-as-a-marker-of-overweight-and-obesity-and-cutoff-values-for-bangladeshi-adults
#7
Nazmul Kabir Qureshi, Tanjina Hossain, Mohammed Imrul Hassan, Nazma Akter, Md Mubinur Rahman, Moushumi Moriam Sultana, S M Ashrafuzzaman, Zafar Ahmed Latif
Objective: There are several methods of assessing overweight and obesity. Several studies conducted in different populations indicate that neck circumference (NC) can be used as a simple measure of overweight and obesity. This study was conducted to evaluate NC as a marker of overweight and obesity and to determine respective cutoff values for Bangladeshi male and female participants. Research Design/Materials and Methods: This cross-sectional observational study was conducted with during July 2013-June 2014 among randomly selected 871 Bangladeshi participants (male = 496 [56...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29283748/femoral-neck-stress-in-older-adults-during-stair-ascent-and-descent
#8
Chen Deng, Jason C Gillette, Timothy R Derrick
A detailed understanding of the hip loading environment is needed to help prevent hip fractures, minimize hip pain, rehabilitate hip injuries and design osteogenic exercises for the hip. The purpose of this study was to compare femoral neck stress during stair ascent and descent and to identify the contribution of muscles and reaction forces to the stress environment in mature adult subjects (n=17; age: 50-65 years). Motion analysis and inverse dynamics were combined with musculoskeletal modelling and optimization, then used as input to an elliptical femoral neck cross-section model to estimate femoral neck stress...
December 28, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/29282073/responsiveness-of-clinical-tests-for-people-with-neck-pain
#9
René Jørgensen, Inge Ris, Carsten Juhl, Deborah Falla, Birgit Juul-Kristensen
BACKGROUND: Responsiveness of a clinical test is highly relevant in order to evaluate the effect of a given intervention. However, the responsiveness of clinical tests for people with neck pain has not been adequately evaluated. The objective of the present study was to examine the responsiveness of four clinical tests which are low cost and easy to perform in a clinical setting, including the craniocervical flexion test, cervical active range of movement, test for the cervical extensors and pressure pain threshold testing...
December 28, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29274161/lower-lip-squamous-cell-carcinoma-in-patients-with-photosensitive-disorders-analysis-of-cases-treated-at-the-brazilian-national-cancer-institute-inca-from-1999-to-2012
#10
J-F-P Borges, N Lanaro, V Bernardo, R Albano, F Dias, P de Faria, L Pinto, S-Q Lourenco
BACKGROUND: Lower lip squamous cell carcinoma (LLSCC) is a common malignancy of the head and neck, being mainly a consequence of a chronic exposure to ultraviolet (UV) light solar radiation. Here, we evaluated the clinicopathological profile of patients with photosensitive disorders (xeroderma pigmentosum, lupus erythematosus and albinism) that developed LLSCC. MATERIAL AND METHODS: Data from patients who had a diagnosed LLSCC with a prior xeroderma pigmentosum, lupus erythematosus or albinism diagnosis that were treated at INCA from 1999 to 2012 were collected from patients medical records (n=16)...
December 23, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29259395/cervical-spine-mechanism-for-reproduction-of-the-biomechanical-behaviours-of-the-human-neck-during-rotation-traction-manipulation
#11
Yuancan Huang, Shuai Li, Minshan Feng, Liguo Zhu
Rotation-traction (RT) manipulation is a commonly used physical therapy procedure in TCM (traditional Chinese medicine) for cervical spondylosis. This procedure temporarily separates the C3 and C4 cervical vertebrae from each other when a physician applies a jerky action while the neck is voluntarily turned by the patient to a specific position as instructed by the physician, where the cervical vertebrae are twisted and locked. However, a high rate of cervical injury occurs due to inexperienced physician interns who lack sufficient training...
2017: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/29249574/ultimate-force-and-stiffness-of-2-piece-zirconium-dioxide-implants-with-screw-retained-monolithic-lithium-disilicate-reconstructions
#12
Tim Joda, Benjamin Voumard, Philippe K Zysset, Urs Brägger, Marco Ferrari
PURPOSE: The aims were to analyze stiffness, ultimate force, and failure modes of a 2-piece zirconium dioxide (ZrO2) implant system. METHODS: Eleven 2-piece ZrO2 implants, each mounted with ZrO2 abutments plus bonded monolithic lithium disilicate (LS2) restorations, were grouped for 3.3mm (A) and 4.1mm (B) diameter samples. Quasi-static load was monotonically applied under a standardized test set-up (loading configuration according to DIN ISO 14801). The ultimate force was defined as the maximum force that implants are able to carry out until fracture; stiffness was measured as the maximum slope during loading...
December 14, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/29246721/functional-outcomes-after-de-escalated-chemoradiation-therapy-for-human-papillomavirus-positive-oropharyngeal-cancer-secondary-analysis-of-a-phase-2-trial
#13
John V Hegde, Narek Shaverdian, Carol Felix, Pin-Chieh Wang, Darlene Veruttipong, Sophia Hsu, Jonathan W Riess, Shyam D Rao, Megan E Daly, Allen M Chen
PURPOSE: To analyze functional outcomes for patients treated on a phase 2 trial of de-escalated chemoradiation therapy for human papillomavirus-positive oropharyngeal cancer. METHODS AND MATERIALS: Patient eligibility included p16-positive, stage III or IV oropharyngeal squamous cell carcinoma and a Zubrod performance status of 0 to 1. Treatment was induction chemotherapy with paclitaxel, 175 mg/m2, and carboplatin, area under the curve (AUC) of 6 mg/ml/min, for 2 cycles every 21 days, followed by concurrent paclitaxel, 30 mg/m2, every 7 days with dose-reduced radiation therapy of 54 or 60 Gy...
November 6, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29246717/comparative-analysis-of-the-reconstruction-of-individual-hip-anatomy-using-3-different-cementless-stem-designs-in-patients-with-primary-hip-osteoarthritis
#14
Moritz M Innmann, Katrin Spier, Marcus R Streit, Peter R Aldinger, Thomas Bruckner, Tobias Gotterbarm, Christian Merle
BACKGROUND: We questioned whether there was a radiographic difference in hip geometry reconstruction and implant fixation between 3 different cementless stem design concepts in patients with primary end-stage hip osteoarthritis. METHODS: We retrospectively evaluated the preoperative and postoperative radiographs by 2 independent and blinded reviewers in a series of 264 consecutive patients who had received either a straight double-tapered stem with 3 offset options (group A), a straight double-tapered stem with 2 shape options and modular necks (group B), and a bone-preserving curved tapered stem with 4 offset options (group C)...
November 21, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29246667/serum-25-hydroxybitamin-d-bone-turnover-markers-and-bone-mneral-density-in-postmenopausal-women
#15
Liang He, Jixing Fan, Ning Li, Xiaogong Feng
BACKGROUND: We explored the relationship between serum 25(OH)D, bone turnover markers and bone mineral density in Chinese postmenopausal women with hip fracture. METHODS: A total of 277 patients with hip fractures and 272 patients without fractures were included in this study. The serum 25(OH)D, bone formation markers, including N-terminal extension propeptide of type-I collagen (P1NP), alkaline phosphatase (ALP) and osteocalcin(OC), bone resorption markers, including C-terminal telopeptide of type-I collagen (CTX-1), and bone mineral density were collected and analyzed...
December 12, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29243996/validation-of-the-visual-analog-scale-in-the-cervical-spine
#16
Anna MacDowall, Martin Skeppholm, Yohan Robinson, Claes Olerud
OBJECTIVE The visual analog scale (VAS) is frequently used to measure treatment outcome in patients with cervical spine disorders. The minimum clinically important difference (MCID) is the smallest change in a score that has clinical importance to the patient. Although it has been established for other medical fields, knowledge of the VAS MCID for the cervical spine is sparse, and it has rarely been considered in relation to measurement noise. The goals in this study were as follows: 1) to validate the VAS-neck and VAS-arm instruments for the cervical spine (e...
December 15, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29243981/assessment-of-intracranial-venous-blood-flow-after-subarachnoid-hemorrhage-a-new-approach-to-diagnose-vasospasm-with-transcranial-color-coded-duplex-sonography
#17
Florian Connolly, Stephan J Schreiber, Christoph Leithner, Georg Bohner, Peter Vajkoczy, José M Valdueza
OBJECTIVE Transcranial color-coded duplex sonography (TCCS) is a reliable tool that is used to assess vasospasm in the M1 segment of the middle cerebral artery (MCA) after subarachnoid hemorrhage (SAH). A distinct increase in blood flow velocity (BFV) is the principal criterion for vasospasm. The MCA/internal carotid artery (ICA) index (Lindegaard Index) is also widely used to distinguish between vasospasm and cerebral hyperperfusion. However, extracranial ultrasonography assessment of the neck vessels might be difficult in an intensive care unit...
December 15, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29235924/unplanned-stents-in-thoracic-endovascular-aortic-repair-for-type-b-aortic-dissection-a-16-year-single-center-report
#18
Junjun Liu, Rongjie Zhang, Rui Feng, Jiaxuan Feng, Zhiqing Zhao, Zhenjiang Li, Yuxi Zhao, Yiming Li, Jian Zhou, Zaiping Jing
Background Unplanned stents in thoracic endovascular aortic repair mean additional stents implantation beyond the preoperative planning to achieve operation success. This study aimed to reveal the prevalence and consequences of unplanned stents in thoracic endovascular aortic repair for type B aortic dissection and explore the reasons, risk factors and solutions for unplanned stents. Methods Retrospectively analysis consecutive patients diagnosed as type B aortic dissection with initial tear originating distal from the left subclavian artery and underwent thoracic endovascular aortic repair from September 1998 to June 2014 in our center...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/29234624/thyroidectomy-improves-tracheal-anatomy-and-airflow-in-patients-with-nodular-goiter-a-prospective-cohort-study
#19
Jesper Roed Sorensen, Jeppe Faurholdt Lauridsen, Helle Døssing, Nina Nguyen, Laszlo Hegedüs, Steen Joop Bonnema, Christian Godballe
Objective: A large goiter may cause compression of the trachea. The aim of this study was to investigate the impact of thyroidectomy on tracheal anatomy and airflow and to correlate this with changes in health-related quality of life (HRQoL) in patients with benign nodular goiter. Methods: Magnetic resonance images of the neck and respiratory flow-volume curves, including both inspiration and expiration, were performed prior to and 6 months following surgery. HRQoL was measured by selected scales from the thyroid-specific patient-reported outcome (ThyPRO)...
November 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/29232883/same-abbreviated-injury-scale-values-may-be-associated-with-different-risks-to-mortality-in-trauma-patients-a-cross-sectional-retrospective-study-based-on-the-trauma-registry-system-in-a-level-i-trauma-center
#20
Cheng-Shyuan Rau, Shao-Chun Wu, Pao-Jen Kuo, Yi-Chun Chen, Peng-Chen Chien, Hsiao-Yun Hsieh, Ching-Hua Hsieh
The Abbreviated Injury Scale (AIS) measures injury severity of a trauma patient with a numeric method for ranking anatomy-based specific injuries. The summation of the squares of the three most severe injuries in the AIS of six predefined body regions comprises the Injury Severity Score (ISS). It assumes that the mortality of a given AIS value is similar across all body regions. However, such an assumption is less explored in the literature. In this study, we aimed to compare the mortality rates of the patients with the same AIS value in different injured body regions in a level I trauma center...
December 11, 2017: International Journal of Environmental Research and Public Health
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