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https://www.readbyqxmd.com/read/29144029/neck-circumference-a-valuable-anthropometric-measurement-to-detect-metabolic-syndrome-among-different-age-groups-in-china
#1
Ting Cui, Ban-Huao Yan, Zhan Liu, Hui Yang, Michael Gyan, Yu-Xia Ma
OBJECTIVES: The aim of this study was to investigate the correlation between neck circumference (NC) and metabolic syndrome (MS) in Chinese residents and to explore the cut-off points of NC for MS in different age groups. METHODS: In all, 4227 Chinese adults (18-90 years) were enrolled in the study and divided into three subgroups (young, middle-aged and elderly) according to their ages. The compared data for the subjects included anthropometric indicators and biochemical detection indices...
November 16, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/29142848/injury-of-the-external-branch-of-the-superior-laryngeal-nerve-in-thyroid-surgery
#2
REVIEW
Andre S Potenza, Vergilius J F Araujo Filho, Claudio R Cernea
The external branch of the superior laryngeal nerve (EBSLN) innervates the cricothyroid muscle (CTM) to promote lengthening and thinning of the vocal fold, thus increasing voice pitch. The close relation with the superior thyroid vessels (STV) puts the EBSLN in risk every time the superior pole of the thyroid is dissected. It travels downward to innervate the CTM, lateral to the thyroid cartilage and to the inferior pharyngeal constrictor muscle (IPCM), being eventually covered by this muscle fibers as it approaches its entry point...
October 2017: Gland Surgery
https://www.readbyqxmd.com/read/29142656/pharyngeal-airway-dimensions-and-head-posture-in-obstructive-sleep-apnea-patients-with-and-without-morphological-deviations-in-the-upper-cervical-spine
#3
Liselotte Sonnesen, Arne Petersson, Søren Berg, Palle Svanholt
Objectives: The aim of the study was to analyse differences in pharyngeal airway dimensions and head posture between obstructive sleep apnea patients with and without morphological deviations in the upper cervical spine and to analyse associations between pharyngeal airway dimensions and head posture in the total sample. Material and Methods: The sample comprised 53 obstructive sleep apnea (OSA) patients of which 32.1% had upper spine morphological deviations. Accordingly two groups were defined: 17 OSA patients with morphological deviations in the upper spine and 36 without upper spine deviations...
July 2017: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/29130107/a-seven-gene-prognostic-signature-for-rapid-determination-of-head-and-neck-squamous-cell-carcinoma-survival
#4
Sipeng Shen, Jianling Bai, Yongyue Wei, Guanrong Wang, Qingya Li, Ruyang Zhang, Weiwei Duan, Sheng Yang, Mulong Du, Yang Zhao, David C Christiani, Feng Chen
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer and displays divergent clinical outcomes. Prognostic biomarkers might improve risk stratification and survival prediction. We aimed to investigate the prognostic genes associated with overall survival. A two-step gene selection method was used to develop a seven-gene-based prognostic model based on the training set collected from The Cancer Genome Atlas (TCGA). In addition, the prognostic model was validated in an independent testing set from Gene Expression Omnibus (GEO)...
December 2017: Oncology Reports
https://www.readbyqxmd.com/read/29123432/a-pictorial-sleepiness-and-sleep-apnoea-scale-to-recognize-individuals-with-high-risk-for-obstructive-sleep-apnea-syndrome
#5
Cathrin Edelmann, Ramesh Ghiassi, Deborah R Vogt, Martyn R Partridge, Ramin Khatami, Jörg D Leuppi, David Miedinger
Purpose: The aim of this study was to evaluate the validity of a new pictorial form of a screening test for obstructive sleep apnea syndrome (OSAS) - the pictorial Sleepiness and Sleep Apnoea Scale (pSSAS). Validation was performed in a sample of patients admitted to sleep clinics in the UK and Switzerland. Patients and methods: All study participants were investigated with objective sleep tests such as full-night-attended polysomnography or polygraphy. The pSSAS was validated by taking into account the individual result of the sleep study, sleep-related questionnaires and objective parameters such as body mass index (BMI) or neck circumference...
2017: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29115210/surgeon-performed-ultrasonography
#6
Tobias Todsen
Surgeons are increasingly using ultrasonography (US) in their clinical management of patients. However, US is a very user-dependent imaging modality and proper skills of the US operator are needed to ensure quality in patient care. This thesis explores the validity evidence for assessment of competence in abdominal and head & neck ultrasonography using the Objective Structured Assessment of Ultrasound Skills (OSAUS) scale. With the use of Messick's unitary framework of validity, five sources of validity evidence were explored: test content, response processes, inter-nal structure, relations to other variables, and consequences...
November 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/29114619/incorporating-big-data-into-treatment-plan-evaluation-development-of-statistical-dvh-metrics-and-visualization-dashboards
#7
Charles S Mayo, John Yao, Avraham Eisbruch, James M Balter, Dale W Litzenberg, Martha M Matuszak, Marc L Kessler, Grant Weyburn, Carlos J Anderson, Dawn Owen, William C Jackson, Randall Ten Haken
Purpose: To develop statistical dose-volume histogram (DVH)-based metrics and a visualization method to quantify the comparison of treatment plans with historical experience and among different institutions. Methods and materials: The descriptive statistical summary (ie, median, first and third quartiles, and 95% confidence intervals) of volume-normalized DVH curve sets of past experiences was visualized through the creation of statistical DVH plots. Detailed distribution parameters were calculated and stored in JavaScript Object Notation files to facilitate management, including transfer and potential multi-institutional comparisons...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29114180/head-and-neck-cancer-tumor-segmentation-using-support-vector-machine-in-dynamic-contrast-enhanced-mri
#8
Wei Deng, Liangping Luo, Xiaoyi Lin, Tianqi Fang, Dexiang Liu, Guo Dan, Hanwei Chen
Objective: We aimed to propose an automatic method based on Support Vector Machine (SVM) and Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to segment the tumor lesions of head and neck cancer (HNC). Materials and Methods: 120 DCE-MRI samples were collected. Five curve features and two principal components of the normalized time-intensity curve (TIC) in 80 samples were calculated as the dataset in training three SVM classifiers. The other 40 samples were used as the testing dataset...
2017: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29113308/kdm4a-as-a-prognostic-marker-of-oral-squamous-cell-carcinoma-evidence-from-tissue-microarray-studies-in-a-multicenter-cohort
#9
Xin Jin, Hao Xu, Xingyu Wu, Taiwen Li, Jing Li, Yu Zhou, Hongxia Dan, Lu Jiang, Xin Zeng, Ping Ji, Qianming Chen
Purpose: Previous studies have identified histone demethylase KDM4A to be a key epigenetic priming factor for the invasive squamous cell carcinoma growth and metastasis. The purpose of this study was to examine KDM4A as an independent prognostic marker in oral squamous cell carcinoma, using multicenter tissue microarrays. Results: The expression of KDM4A was significantly correlated with lymph node metastasis and TNM stage. KDM4A overexpression was associated with poor overall survival, and it was found to be a statistically significant independent predictor of all-cause mortality...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29111185/morphological-characteristics-associated-with-rupture-risk-of-multiple-intracranial-aneurysms
#10
Guang-Xian Wang, Lan-Lan Liu, Li Wen, Yun-Xing Cao, Yu-Chun Pei, Dong Zhang
OBJECTIVE: To identify the morphological parameters that are related to intracranial aneurysms (IAs) rupture using a case-control model. METHODS: A total of 107 patients with multiple IAs and aneurysmal subarachnoid hemorrhage between August 2011 and February 2017 were enrolled in this study. Characteristics of IAs location, shape, neck width, perpendicular height, depth, maximum size, flow angle, parent vessel diameter (PVD), aspect ratio (AR) and size ratio (SR) were evaluated using CT angiography...
October 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/29110580/clinical-significance-of-low-2-methoxyestradiol-levels-in-serum-and-tissue-of-recurrent-juvenile-onset-laryngeal-papillomatosis
#11
Danling Liu, Jiadong Wang, Yanan Xu
Objective We aim to explore the correlation between serum and tissue 2-methoxyestradiol (2-ME-2) levels and recurrence of juvenile-onset respiratory papillomatosis (JORRP). Study Design Retrospective cohort studies. Settings Laboratory of Otolaryngology, Department of Head and Neck Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University. Subjects and Methods Sixty-four patients diagnosed with JORRP in our department from January 2007 to December 2012 were enrolled. Patients were divided into recurrence and nonrecurrence groups, with 32 patients in each group...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29109636/comparison-of-polyvinyl-chloride-curved-reinforced-and-straight-reinforced-endotracheal-tubes-for-tracheal-intubation-through-airtraq%C3%A2-laryngoscope-in-anesthetized-patients
#12
Kush Ashokkumar Goyal, Shaji Mathew, Arun Kumar Handigodu Duggappa, Kanika P Nanda, Souvik Chaudhuri, Renganathan Sockalingam
Background and Aims: The Airtraq™ video laryngoscope facilitates tracheal intubations in patients with difficult airway or cervical spine immobilization. However, curved reinforced tracheal tube and straight reinforced tracheal tubes are useful where neck of the patient is likely to be moved or flexed or if patient is in prone position, wherein nonreinforced endotracheal tube (ETT) might get kinked and/or compressed. We compared intubation success rate of curved and straight reinforced tracheal tubes with polyvinyl chloride (PVC) tracheal tube using Airtaq™ laryngoscope in paralyzed and anesthetized patients...
July 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/29103774/a-single-arm-open-label-clinical-trial-of-autologous-epidermal-cell-transplantation-for-stable-vitiligo-a-30-month-follow-up
#13
Zahra Orouji, Amir Bajouri, Mahshid Ghasemi, Parvaneh Mohammadi, Nasrin Fallah, Atefeh Shahbazi, Mohammad Rezvani, Fatemeh Vaezirad, Zahra Khalajasadi, Ahad Alizadeh, Ehsan Taghiabadi, Sara Dashtbozorgi, Raheleh Aghdami, Seyedeh Esmat Hosseini, Hossein Bahahrvand, Saeed Shafieyan, Nasser Aghdami
BACKGROUND: Recently, we introduced intralesional injection of autologous epidermal cells as a safe and feasible approach for transplantation in patients with stable vitiligo. This approach resulted in less pain during and after the procedure, no scarring or cobblestone formation at the recipient site, and was more feasible to perform on curved surfaces such as joints, lips, eyelids, ears, and face. OBJECTIVE: In this study, we aimed to investigate the long-term efficacy and safety of this transplantation technique...
October 18, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29103748/tumor-thickness-versus-depth-of-invasion-analysis-of-the-8th-edition-american-joint-committee-on-cancer-staging-for-oral-cancer
#14
Richard Dirven, Ardalan Ebrahimi, Nikolaus Moeckelmann, Carsten Erich Palme, Ruta Gupta, Jonathan Clark
OBJECTIVES: The primary aim of this study is to compare the effect of using tumor thickness versus depth of invasion (DOI) to determine the 8th edition AJCC T-category on survival in a large cohort of OSCC. MATERIALS AND METHODS: A retrospective cohort study of patients whose clinicopathologic information had been collected prospectively into a dedicated head and neck database. 927 patients with oral SCC were identified in this cohort, with the final study population including 456 patients with complete information on DOI, tumor thickness, T and N staging and follow-up...
November 2017: Oral Oncology
https://www.readbyqxmd.com/read/29102773/appropriate-neck-circumference-cut-off-points-for-metabolic-syndrome-in-turkish-patients-with-type-2-diabetes
#15
Ismail Ozkaya, Bulent Yardimci, Aydin Tunckale
OBJECTIVE: To investigate the association between neck circumference (NC), overweight, and metabolic syndrome (MS) in Turkish patients with type 2 diabetes. METHODS: A total of 264 diabetic patients (mean age: 52.9±8.1 years) were recruited from two centers in Istanbul to perform anthropometric measurements, including waist and hip circumference, NC, and body mass index. Blood pressure, fasting glucose, and lipid profile (total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglyceride levels) were determined...
November 1, 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/29101409/characterization-of-trabecular-bone-microstructure-in-premenopausal-women-with-distal-radius-fractures
#16
T D Rozental, F Johannesdottir, K C Kempland, M L Bouxsein
Individual trabecular segmentation was utilized to identify differences in trabecular bone structure in premenopausal women with wrist fractures and non-fracture controls. Fracture subjects had reduced trabecular plate volume, number, thickness, and connectivity. Identifying altered trabecular microarchitecture in young women offers opportunities for counseling and lifestyle modifications to reduce fracture risk. INTRODUCTION: Premenopausal women with distal radius fractures (DRF) have worse trabecular bone microarchitecture than non-fracture controls (CONT), yet the characteristics of their trabecular bone structure are unknown...
November 3, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29100453/preoperative-vitamin-d-deficiency-and-postoperative-hypocalcemia-in-thyroid-cancer-patients-undergoing-total-thyroidectomy-plus-central-compartment-neck-dissection
#17
Xiaofei Wang, Jingqiang Zhu, Feng Liu, Yanping Gong, Zhihui Li
Background: There appears to be a lack of consensus whether preoperative vitamin D deficiency (VDD) increases the risk of postoperative hypocalcemia and decreases the accuracy of postoperative parathyroid hormone (PTH) in predicting hypocalcemia in thyroid cancer patients undergoing total thyroidectomy (TT) plus central compartment neck dissection (CCND). This study aims to address these issues. Method: All consecutive thyroid cancer patients who underwent TT plus CCND were retrospectively reviewed through a prospectively collected database between October 2015 and April 2016 in a tertiary referral hospital...
September 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29095680/prediction-of-ischemic-heart-disease-and-stroke-in-survivors-of-childhood-cancer
#18
Eric J Chow, Yan Chen, Melissa M Hudson, Elizabeth A M Feijen, Leontien C Kremer, William L Border, Daniel M Green, Lillian R Meacham, Daniel A Mulrooney, Kirsten K Ness, Kevin C Oeffinger, Cécile M Ronckers, Charles A Sklar, Marilyn Stovall, Helena J van der Pal, Irma W E M van Dijk, Flora E van Leeuwen, Rita E Weathers, Leslie L Robison, Gregory T Armstrong, Yutaka Yasui
Purpose We aimed to predict individual risk of ischemic heart disease and stroke in 5-year survivors of childhood cancer. Patients and Methods Participants in the Childhood Cancer Survivor Study (CCSS; n = 13,060) were observed through age 50 years for the development of ischemic heart disease and stroke. Siblings (n = 4,023) established the baseline population risk. Piecewise exponential models with backward selection estimated the relationships between potential predictors and each outcome. The St Jude Lifetime Cohort Study (n = 1,842) and the Emma Children's Hospital cohort (n = 1,362) were used to validate the CCSS models...
November 2, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29075808/the-kidney-liver-index-surgery-and-c-reactive-protein-score-is-a-predictor-of-treatment-response-in-acute-prosthetic-joint-infection
#19
C Jiménez-Garrido, J M Gómez-Palomo, I Rodriguez-Delourne, F J Durán-Garrido, E Nuño-Álvarez, E Montañez-Heredia
PURPOSE: This work seeks to verify the utility of the KLIC score as a predictor of treatment success or failure in patients with knee and hip acute prosthetic joint infections (APJI). These patients were treated in our centre, which is not a prosthetic joint infection reference centre. The KLIC score assesses factors such as chronic kidney failure (2 points) (Kidney), liver disease (1.5 points) (Liver), revision surgery or femoral neck fracture (1.5 points)and cemented prosthesis (2 points) (Index surgery) and a C-reactive protein level (CRP) greater than 11...
October 26, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29072678/specific-detection-of-soluble-epha2-fragments-in-blood-as-a-new-biomarker-for-pancreatic-cancer
#20
Naohiko Koshikawa, Tomoko Minegishi, Hirofumi Kiyokawa, Motoharu Seiki
Because membrane type 1-matrix metalloproteinase 1 (MT1-MMP) and erythropoietin-producing hepatocellular receptor 2 (EphA2) expression are upregulated by the Ras/mitogen-activated protein kinase pathway, they are frequently coexpressed in malignant tumors. MT1-MMP cleaves the N-terminal ligand-binding domain of EphA2 and inactivates its ligand-dependent tumor-suppressing activity. Therefore, specific detection of the cleaved N-terminal EphA2 fragment in blood might be an effective biomarker to diagnose malignant tumors...
October 26, 2017: Cell Death & Disease
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