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https://www.readbyqxmd.com/read/29787868/individualized-tractography-based-parcellation-of-the-globus-pallidus-pars-interna-using-7t-mri-in-movement-disorder-patients-prior-to-dbs-surgery
#1
Rémi Patriat, Scott E Cooper, Yuval Duchin, Jacob Niederer, Christophe Lenglet, Joshua Aman, Michael C Park, Jerrold Vitek, Noam Harel
The success of deep brain stimulation (DBS) surgeries for the treatment of movement disorders relies on the accurate placement of an electrode within the motor portion of subcortical brain targets. However, the high number of electrodes requiring relocation indicates that today's methods do not ensure sufficient accuracy for all patients. Here, with the goal of aiding DBS targeting, we use 7 T (T) MRI data to identify the functional territories and parcellate the globus pallidus interna (GPi) into motor, associative and limbic regions in individual subjects...
May 19, 2018: NeuroImage
https://www.readbyqxmd.com/read/29784882/phenotypic-assessment-suggests-multiple-start-codons-for-hetn-an-inhibitor-of-heterocyst-differentiation-in-anabaena-sp-strain-pcc-7120
#2
Orion S Rivers, Silvia Beurmann, Allexa Dow, Loralyn M Cozy, Patrick Videau
Multicellular organisms must carefully regulate the timing, number, and location of specialized cellular development. In the filamentous cyanobacterium Anabaena sp. strain PCC 7120, nitrogen-fixing heterocysts are interspersed between vegetative cells in a periodic pattern to achieve optimal exchange of bioavailable nitrogen and reduced carbon. The spacing between heterocysts is regulated by the activity of two developmental inhibitors: PatS and HetN. PatS functions to create a de novo pattern from a homogenous field of undifferentiated cells, while HetN maintains the pattern throughout subsequent growth...
May 21, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29783793/summary-of-u-s-injuries-and-fatalities-involving-entrapment-and-suffocation-in-grain-transport-vehicles
#3
Yuan-Hsin Cheng, William E Field, Salah F Issa, Kevin Kelley, Matthew Heber, Robert Turner
Since 1978, the Purdue University Agricultural Safety and Health Program has managed a surveillance effort and database to collect information on documented injuries and fatalities in all forms of U.S. agricultural confined spaces. The database currently contains 1,968 cases documented in the U.S. between 1964 and 2016. Of these cases, 174 (8.8%) involved entrapment or suffocation in grain transport vehicles (GTVs), including gravity-flow wagons, semi-truck trailers, and other agricultural transport vehicles that have limited access and are not considered normal work spaces or are classified as confined spaces...
May 7, 2018: Journal of Agricultural Safety and Health
https://www.readbyqxmd.com/read/29783212/changes-in-biochemical-parameters-of-oral-fluid-in-patients-during-the-orthodontic-treatment-with-a-bracket-system-under-the-action-of-a-developed-mucosal-gel-with-probiotic
#4
Anna V Voronkova, Lyubov V Smaglyuk
OBJECTIVE: Introduction: Many research studies involving orthodontic patients focus on changes in levels of oral microbiocenosis after bracket placement. Based upon this the objective of the current study was to determine the effect of the developed mucosal gel with probiotics on the biochemical parameters of the oral fluid of patients during the orthodontic treatment with a bracket system. The aim: Aim of our study is to determine the effect of the developed mucosal gel with probiotics on the biochemical parameters of the oral fluid of patients during the orthodontic treatment with a bracket system...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29766033/use-of-key-performance-indicators-to-improve-milestone-assessment-in-semi-annual-clinical-competency-committee-meetings
#5
Fei Chen, Harendra Arora, Susan M Martinelli
Background: The Accreditation Council for Graduate Medical Education's Next Accreditation System requires residency programs to semiannually submit composite milestone data on each resident's performance. This report describes and evaluates a new assessment review procedure piloted in our departmental Clinical Competency Committee (CCC) semi-annual meeting in June 2016. Methods: A modified Delphi technique was utilized to develop key performance indicators (KPI) linking milestone descriptors to clinical practice...
October 2017: Journal of Education in Perioperative Medicine: JEPM
https://www.readbyqxmd.com/read/29764267/clinical-narratives-in-residency-education-exploration-of-the-learning-process
#6
Jennifer A Furze, Bruce H Greenfield, J B Barr, Kathleen Geist, Judith Gale, Gail M Jensen
BACKGROUND: Post-professional residency educational programs aim to advance the knowledge and skills of therapists in a clinical specialty area, however, little is known about the process, outcomes, or effectiveness of residency education. PURPOSE: The purpose of this study was to use narrative as a teaching and learning tool to gain insight into the progressive development of the residents' learning process. DESIGN: Qualitative methods including a retrospective analysis of residents' narratives were used to explore the professional development and thought process of residents...
May 15, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29757719/providing-mr-imaging-for-cervical-cancer-brachytherapy-lessons-for-radiologists
#7
Thomas Sullivan, Joseph H Yacoub, Matthew M Harkenrider, William Small, Murat Surucu, Steven M Shea
Brachytherapy (BT), the use of a locally placed or implanted radioactive source for treatment of an adjacent tumor, is an important component in the treatment of patients with both early- and advanced-stage cervical cancer and is increasingly part of the standard treatment protocol. When it is feasible, many radiation oncologists choose to include a magnetic resonance (MR) imaging examination for planning BT treatment (ie, an MR imaging examination after placement of the applicator but before radiation dosing)...
May 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29753159/defining-incidence-and-risk-factors-for-catheter-associated-bloodstream-infections-in-an-outpatient-adult-hematopoietic-cell-transplant-program
#8
Marissa K McDonald, Kathryn A Culos, Katie S Gatwood, Caleb Prow, Heidi Chen, Bipin N Savani, Michael Byrne, Adetola A Kassim, Brian G Engelhardt, Madan Jagasia, Gowri Satyanarayana
BACKGROUND: Allogeneic hematopoietic cell transplant (HCT) patients are at an increased risk of developing central line-associated bloodstream infections (CLABSIs) due to prolonged periods of myelosuppression, immunosuppression, and indwelling catheter days. CLABSIs are among the most serious complications in HCT recipients and can lead to prolonged hospitalizations, intensive care unit (ICU) admissions, lengthy antimicrobial therapies, and increased mortality. There is a lack of data regarding the incidence and risk factors associated with the development of CLABSIs in the HCT population undergoing outpatient transplantation...
May 9, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29751144/the-homelessness-prevention-and-re-housing-outcomes
#9
Molly Brown, Lauren Klebek, Gia Chodzen, Samantha Scartozzi, Camilla Cummings, Alejandro Raskind
The Homelessness Prevention and Rapid Re-housing Program (HPRP) was a federally-funded program in the United States that provided short-term financial and support services to individuals and families who were at-risk or currently experiencing homelessness. There is limited research on factors that predict placement in permanent housing following prevention and rapid rehousing interventions, particularly for single adult populations. The present study examined demographic and program-related predictors of permanent housing upon program exit among two groups of adults enrolled in HPRP in Indianapolis, IN: Homelessness Prevention (HP) recipients (n = 219) and Rapid Re-housing (RRH) recipients (n = 296)...
April 30, 2018: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29750754/the-barrow-biomimetic-spine-fluoroscopic-analysis-of-a-synthetic-spine-model-made-of-variable-3d-printed-materials-and-print-parameters
#10
Michael A Bohl, Michael A Mooney, Garrett J Repp, Peter Nakaji, Steve W Chang, Jay D Turner, U Kumar Kakarla
STUDY DESIGN: Objective and subjective fluoroscopic assessments of a new synthetic spine model. OBJECTIVE: To analyze the fluoroscopic performance and fidelity to human tissue of a new synthetic spine model. SUMMARY OF BACKGROUND DATA: The [blinded for review] Biomimetic Spine project aims to develop a 3-dimensional (3D) printed, synthetic spine model that will one day replace cadaveric tissue in spine biomechanical research. A crucial component to any biomimetic spine model is that it performs similarly to cadaveric tissue on standard diagnostic imaging modalities...
May 10, 2018: Spine
https://www.readbyqxmd.com/read/29737441/long-term-supportive-housing-is-associated-with-decreased-risk-for-new-hiv-diagnoses-among-a-large-cohort-of-homeless-persons-in-new-york-city
#11
Christopher T Lee, Andrea Winquist, Ellen W Wiewel, Sarah Braunstein, Hannah T Jordan, L Hannah Gould, R Charon Gwynn, Sungwoo Lim
It is unknown whether providing housing to persons experiencing homelessness decreases HIV risk. Housing, including access to preventive services and counseling, might provide a period of transition for persons with HIV risk factors. We assessed whether the new HIV diagnosis rate was associated with duration of supportive housing. We linked data from a cohort of 21,689 persons without a previous HIV diagnosis who applied to a supportive housing program in New York City (NYC) during 2007-2013 to the NYC HIV surveillance registry...
May 8, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29732645/procedural-sedation-in-children-with-autism-spectrum-disorders-a-survey-of-current-practice-patterns-of-the-society-for-pediatric-sedation-members
#12
Pradip P Kamat, Leah N Bryan, Courtney E McCracken, Harold K Simon, John W Berkenbosch, Jocelyn R Grunwell
BACKGROUND: Children with autism spectrum disorder are challenging to sedate because of communication, sensory, and behavioral challenges. AIMS: The aim of this survey was to determine how procedural sedation is provided to children with autism spectrum disorders and whether sedation programs have specialized protocols for procedural sedation of these children. METHODS: We surveyed physician Medical Directors of sedation programs who are members of the Society for Pediatric Sedation, asking about practice characteristics and resource utilization during procedural sedation of children with autism spectrum disorders...
May 6, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29728925/student-perspectives-on-the-impact-of-an-undergraduate-work-integrated-learning-program-on-admission-and-transition-to-medical-school
#13
Rachel McDonald, Adam Bobrowski, Leah Drost, Leigha Rowbottom, Judene Pretti, Hany Soliman, Stephanie Chan, Edward Chow
Work-integrated learning (WIL) is a form of education that integrates academic and workplace study. Such programs provide students the opportunity to concurrently develop cognitive and non-cognitive competencies. The purpose of this study is to explore which experiences and skills learned in a WIL placement are useful in applying to medical school and transitioning into the first year of a Doctor of Medicine program. All individuals who worked in the Rapid Response Radiotherapy Program (RRRP; WIL placement) since 2004 and had completed at least 1 year of medical school were invited to participate...
May 5, 2018: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29728866/pregnancy-in-women-with-psychotic-disorders-risk-factors-associated-with-mother-baby-separation
#14
Agathe Cès, Bruno Falissard, Nine M C Glangeaud-Freudenthal, Anne-Laure Sutter-Dallay, Florence Gressier
Pregnancy in women suffering from psychotic disorders is becoming more common. However, this psychiatric disorder is linked to the highest risk of early mother and child separation. The aim of this study was to evaluate risk factors associated with these separations. In an observational, naturalist, and multicentric study, 320 women suffering from a psychotic disorder and jointly hospitalized with their child in one of the sixteen mother-baby units (MBUs) in France and Belgium between 2001 and 2010 were assessed for risk factors associated with mother-child separation...
May 4, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29728555/prosthetic-rehabilitation-using-a-telescopic-crown-constructed-with-computer-assisted-design-and-computer-assisted-manufacturing-a-case-report-with-a-2-year-follow-up
#15
Nasser M Al Ahmari
Aim and background: This case report describes a 74-year-old female patient whose teeth were rehabilitated using telescopic crowns (TCs) on abutments and fixed dental prostheses (FDPs) in the maxillary arch with the aid of computer-assisted design and computer-assisted manufacturing (CAD/CAM) technology. The mandibular arch was restored using casted removable dental prostheses (RDPs) and surveyed crowns. Case report: The treatment sequences were followed as recommended in the dental literature. First, existing defective restorations were eliminated, caries was removed, and excellent mouth preparation was performed...
April 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29724107/mapping-the-interprofessional-education-landscape-for-students-on-rural-clinical-placements-an-integrative-literature-review
#16
Lorraine Walker, Merylin Cross, Tony Barnett
INTRODUCTION: Interprofessional collaboration and effective teamwork are core to optimising rural health outcomes; however, little is known about the opportunities available for interprofessional education (IPE) in rural clinical learning environments. This integrative literature review addresses this deficit by identifying, analysing and synthesising the research available about the nature of and potential for IPE provided to undergraduate students undertaking rural placements, the settings and disciplines involved and the outcomes achieved...
May 2018: Rural and Remote Health
https://www.readbyqxmd.com/read/29723597/hybrid-ear-cubes-for-local-controlled-dexamethasone-delivery-to-the-inner-ear
#17
M Gehrke, J Verin, D Gnansia, G Tourrel, M Risoud, C Vincent, F Siepmann, J Siepmann
A new type of miniaturized implants for local controlled drug delivery to the inner ear is proposed: Hybrid Ear Cubes. They are composed of two main parts: (i) a cylinder, which is placed into a tiny hole (<0.4 mm) drilled into (or close to) the oval (or round) window, and (ii) a cuboid, which is placed into the middle ear. The drug is released at a pre-programmed rate into the perilymph: (i) via the cylindrical part of the implant, which is in direct contact with this liquid, and (ii) via diffusion from the cuboid through the oval/round window...
April 30, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29723021/promising-practices-in-vocational-services-for-the-community-reintegration-of-returning-veterans-the-individual-placement-and-support-model-and-beyond
#18
Nancy J Wewiorski, Jay A Gorman, Arielle A J Scoglio, Seiya Fukuda, Erin Reilly, Lisa Mueller, Maureen O'Connor, Walter E Penk, Charles E Drebing
Supporting returning veterans' job-seeking, hiring, and retention issues has become an essential goal for effective community reintegration. Given both the particular strengths and challenges associated with veterans transitioning from military to civilian life, multiple models for supported employment have become integrated into Veterans Affairs health care facilities across the nation. In this article, we review the state of vocational rehabilitation for veterans, with a particular focus on individual placement and support-supported employment (IPS-SE), the current vocational services model that is considered the gold standard of vocational rehabilitation...
May 2018: Psychological Services
https://www.readbyqxmd.com/read/29710108/association-of-a-proactive-swallowing-rehabilitation-program-with-feeding-tube-placement-in-patients-treated-for-pharyngeal-cancer
#19
Gaurav S Ajmani, Cheryl C Nocon, Bruce E Brockstein, Nicholas P Campbell, Amy B Kelly, Jamie Allison, Mihir K Bhayani
Importance: A proactive speech and language pathology (SLP) program is an important component of the multidisciplinary care of patients with head and neck squamous cell carcinoma (HNSCC). Swallowing rehabilitation can reduce the rate of feeding tube placement, thereby significantly improving quality of life. Objective: To evaluate the initiation of a proactive SLP rehabilitation program at a single institution and its association with rates of feeding tube placement and dietary intake in patients with HNSCC...
April 19, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29705049/proficiency-based-cervical-cancer-brachytherapy-training
#20
Sherry Zhao, Louise Francis, Dorin Todor, Emma C Fields
PURPOSE: Although brachytherapy increases the local control rate for cervical cancer, there has been a progressive decline in its use. Furthermore, the training among residency programs for gynecologic brachytherapy varies considerably, with some residents receiving little to no training. This trend is especially concerning given the association between poor applicator placement and decline in local control. Considering the success of proficiency-based training in other procedural specialties, we developed and implemented a proficiency-based cervical brachytherapy training curriculum for our residents...
April 25, 2018: Brachytherapy
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