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Pc asl

Taiga Itagaki, Christopher T Chenelle, Desmond J Bennett, Daniel F Fisher, Robert M Kacmarek
BACKGROUND: During both nasal noninvasive ventilation (NIV) and invasive ventilation of neonates, the presence of air leaks causes triggering and cycling asynchrony. METHODS: Five ICU ventilators (PB840, PB980, Servo-i, V500, and Avea) were compared in available invasive ventilation and NIV ventilator modes (pressure control continuous spontaneous ventilation [PC-CSV] and pressure control continuous mandatory ventilation [PC-CMV]). The V500 and Avea do not provide PC-CSV and PC-CMV in NIV...
September 20, 2016: Respiratory Care
Siobhan M Hoscheidt, J Mikhail Kellawan, Sara E Berman, Leonardo A Rivera-Rivera, Rachel A Krause, Jennifer M Oh, Michal S Beeri, Howard A Rowley, Oliver Wieben, Cynthia M Carlsson, Sanjay Asthana, Sterling C Johnson, William G Schrage, Barbara B Bendlin
Insulin resistance (IR) is associated with poor cerebrovascular health and increased risk for dementia. Little is known about the unique effect of IR on both micro- and macrovascular flow particularly in midlife when interventions against dementia may be most effective. We examined the effect of IR as indexed by the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) on cerebral blood flow in macro- and microvessels utilizing magnetic resonance imaging (MRI) among cognitively asymptomatic middle-aged individuals...
August 3, 2016: Journal of Cerebral Blood Flow and Metabolism
Robert L Chatburn, Eduardo Mireles-Cabodevila, Madhu Sasidhar
UNLABELLED: Tidal volume (VT) measurement during pressure control (PC) ventilation with preset inspiratory time may produce errors due to patient inspiratory effort. We evaluated VT error in 3 common ICU ventilators. METHODS: Simulated patient: 60kg adult with ARDS using IngMar Medical ASL 5000 having moderate inspiratory effort. Ventilators evaluated: Covidien PB 840, Maquet Servo-i, and Dräger Evita XL, PC breaths at preset inspiratory time (TI) 0.6-1.4s. VT error was defined as ventilator displayed VT minus the simulator displayed VT (mL/kg or % of true)...
August 1, 2016: Computers in Biology and Medicine
P Vilela, M Pimentel, I Sousa, P Figueiredo
Arterial spin labeling (ASL) is a non-invasive MRI technique that allows the quantitative measurement of perfusion, (regional cerebral blood flow (rCBF)). The ASL techniques use the labeling of the blood, by inverting or saturating the spins of water molecules of the blood supplying the imaged region. When reaching the capillary bed, these will be exchanged with tissue water giving rise to a perfusion-weighted signal. The subtraction of control (without label) from labeled images yields a signal difference that directly reflects the local perfusion...
March 29, 2011: Neuroradiology Journal
Andrew J Wheaton, Mitsue Miyazaki
Noncontrast-enhanced magnetic resonance angiography (NCE-MRA) methods have been demonstrated in anatomies throughout the body. Previously established NCE-MRA techniques suffered from long scan times or low sensitivity. Advances in hardware and software have made NCE-MRA scan times clinically feasible. Recent concerns over the safety of gadolinium-based contrast material combined with the expense of the material and its administration have generated a demand for NCE-MRA. In response, several new NCE-MRA methods have been developed...
August 2012: Journal of Magnetic Resonance Imaging: JMRI
Laxman Mainali, Marija Raguz, Theodore G Camenisch, James S Hyde, Witold K Subczynski
Saturation-recovery (SR) EPR at W-band (94 GHz) to obtain profiles of the membrane fluidity and profiles of the oxygen transport parameter is demonstrated for lens lipid membranes using phosphatidylcholine (n-PC), stearic acid (n-SASL), and cholesterol analog (ASL and CSL) spin labels, and compared with results obtained in parallel experiments at X-band (9.4 GHz). Membranes were derived from the total lipids extracted from 2-year-old porcine lens cortex and nucleus. Two findings are especially significant. First, measurements of the spin-lattice relaxation times T1 for n-PCs allowed T1 profiles across the membrane to be obtained...
September 2011: Journal of Magnetic Resonance
R S Lanzman, P Schmitt, P Kröpil, D Blondin
Especially in regard to the potential risks for the development of nephrogenic systemic fibrosis (NSF) following the administration of Gadolinium-based contrast material, nonenhanced MR angiography (MRA) methods are becoming ever more important. Besides well-established time-of-flight (TOF) and phase-contrast (PC) MRA, alternative imaging techniques based on balanced steady-state free precession (bSSFP) and turbo-spin-echo (TSE) sequences are increasingly used in combination with or without arterial spin labeling (ASL) strategies...
October 2011: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
Marija Raguz, Laxman Mainali, Justyna Widomska, Witold K Subczynski
Electron paramagnetic resonance (EPR) spin-labeling methods were used to study the organization of cholesterol and phospholipids in membranes formed from Chol/POPS (cholesterol/1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylserine) mixtures, with mixing ratios from 0 to 3. It was confirmed using the discrimination by oxygen transport and polar relaxation agent accessibility methods that the immiscible cholesterol bilayer domain (CBD) was present in all of the suspensions when the mixing ratio exceeded the cholesterol solubility threshold (CST) in the POPS membrane...
April 2011: Biochimica et Biophysica Acta
Hanna Järnum, Elena G Steffensen, Linda Knutsson, Ernst-Torben Fründ, Carsten Wiberg Simonsen, Søren Lundbye-Christensen, Ajit Shankaranarayanan, David C Alsop, Finn Taagehøj Jensen, Elna-Marie Larsson
INTRODUCTION: The purpose of this study was to compare the non-invasive 3D pseudo-continuous arterial spin labelling (PC ASL) technique with the clinically established dynamic susceptibility contrast perfusion magnetic resonance imaging (DSC-MRI) for evaluation of brain tumours. METHODS: A prospective study of 28 patients with contrast-enhancing brain tumours was performed at 3 T using DSC-MRI and PC ASL with whole-brain coverage. The visual qualitative evaluation of signal enhancement in tumour was scored from 0 to 3 (0 = no signal enhancement compared with white matter, 3 = pronounced signal enhancement with equal or higher signal intensity than in grey matter/basal ganglia)...
April 2010: Neuroradiology
Golnaz Bahramali, Majid Sadeghizadeh, Samad Amini-Bavil-Olyaee, Seyed-Moayed Alavian, Abbas Behzad-Behbahani, Ahmad Adeli, Mohammad-Reza Aghasadeghi, Safieh Amini, Fereidoun Mahboudi
AIM: To characterize the clinical, serologic and virologic features of hepatitis B virus (HBV) infection in Iranian patients with different stages of liver disease. METHODS: Sixty two patients comprising of 12 inactive carriers, 30 chronic hepatitis patients, 13 patients with liver cirrhosis and 7 patients with hepatocellular carcinoma (HCC) were enrolled in the study. The HBV S, C and basal core promoter (BCP) regions were amplified and sequenced, and the clinical, serologic, phylogenetic and virologic characteristics were investigated...
September 21, 2008: World Journal of Gastroenterology: WJG
K K W Siu, K S Morgan, D M Paganin, R Boucher, K Uesugi, N Yagi, D W Parsons
We seek to establish non-invasive imaging able to detect and measure aspects of the biology and physiology of surface fluids present on airways, in order to develop novel outcome measures able to validate the success of proposed genetic or pharmaceutical therapies for cystic fibrosis (CF) airway disease. Reduction of the thin airway surface liquid (ASL) is thought to be a central pathophysiological process in CF, causing reduced mucociliary clearance that supports ongoing infection and destruction of lung and airways...
December 2008: European Journal of Radiology
H R Arias
This work deals with the localization of the high-affinity non-competitive quinacrine binding site on the muscle-type nicotinic acetylcholine receptor (AChR). Specifically, quantitative steady-state fluorescence spectroscopy is used to determine whether quinacrine binds to a site located at either the annular or the non-annular lipid domain. For this purpose, we measure the ability of spin-labelled phosphatidylcholine (SL-PC) to quench AChR-bound quinacrine, AChR-bound ethidium and membrane-partitioned 7-(9-anthroyloxy)stearate (7-AS) fluorescence...
July 12, 1997: Biochimica et Biophysica Acta
M Pasenkiewicz-Gierula, W K Subczynski, A Kusumi
Rotational diffusion of androstane spin-label (ASL), a sterol analogue, in various phosphatidylcholine (PC)-cholesterol membranes was systematically studied by computer simulation of steady-state ESR spectra as a function of the chain length and unsaturation of the alkyl chains, cholesterol mole fraction, and temperature for a better understanding of phospholipid-cholesterol and cholesterol-cholesterol interactions. Special attention was paid to the differences in the cholesterol effects on ASL motion between saturated and unsaturated PC membranes...
May 1, 1990: Biochemistry
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