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Monkey ultrasonography

Lin Huang, Keng Chen, Fu-Chao Chen, Hui-Yong Shen, Ji-Chao Ye, Zhao-Peng Cai, Xi Lin
This study tried to quantify spinal cord perfusion by using contrast-enhanced ultrasound (CEUS) in rhesus monkey models with acute spinal cord injury. Acute spinal cord perfusion after injury was detected by CEUS, coupling with conventional ultrasound (US) and Color Doppler US (CDFI). Time-intensity curves and perfusion parameters were obtained by autotracking contrast quantification (ACQ) software in the epicenter and adjacent regions of injury, respectively. Neurological and histological examinations were performed to confirm the severity of injury...
June 20, 2017: Oncotarget
Kyo Won Lee, Chan Woo Cho, Ji Eun Lee, Hyojun Park, Gyu-Seong Choi, Woo Kyoung Jeong, Jae Berm Park, Sungjoo Kim
The present study evaluated the anatomic and ultrasonographic features of the liver in normal cynomolgus monkeys (Macaca fascicularis). Healthy, male, cynomolgus monkeys from Cambodia (n = 25; mean age, 58.1 mo) were sedated with ketamine (7 mg/kg) and examined by using 2D and Doppler ultrasonography. We measured the diameters of the vascular structures and bile duct, determined the velocities of the hepatic artery and portal vein, and calculated the resistance index of the hepatic artery. Vessel diameters were: proper hepatic artery, 1...
March 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
Kyo Won Lee Chan Woo Cho Ji Eun Lee Hyojun Park Gyu-Seong Choi Woo Kyoung Jeong Jae Berm Park And Sungjoo Kim
The present study evaluated the anatomic and ultrasonographic features of the liver in normal cynomolgus monkeys (Macacafascicularis). Healthy, male, cynomolgus monkeys from Cambodia (n = 25; mean age, 58.1 mo) were sedated with ketamine (7mg/kg) and examined by using 2D and Doppler ultrasonography. We measured the diameters of the vascular structures and bile duct, determined the velocities of the hepatic artery and portal vein, and calculated the resistance index of the hepatic artery. Vessel diameters were: proper hepatic artery, 1...
February 16, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
Fernanda Luiza de Miranda Lins E Lins, Pedro Mayor, Ednaldo Silva Filho, Aline Amaral Imbeloni, Wellington Bandeira da Silva, Maria Vivina Barros Monteiro, Diana Célia Sousa Nunes-Pinheiro, Frederico Ozanan Barros Monteiro
BACKGROUND: The combined use of renal biochemistry and ultrasonographic imaging may improve the correct management of renal disease. Although renal disease is frequently observed in nonhuman primates, renal function markers have not yet been studied in Squirrel monkeys (Saimiri collinsi). OBJECTIVES: The aim of this study was to establish normal renal biochemistry variables and ultrasonographic features in Squirrel monkeys. MATERIAL AND METHODS: Renal biochemistry variables and ultrasonographic images were documented in 29 healthy Squirrel monkeys (15 males and 14 females)...
February 6, 2017: Veterinary Clinical Pathology
Yukako Homma, Kazuhiro Mori, Yasuhiro Ohnishi, Keisuke Fujioka, Tomomasa Terada, Ayumi Sasaki, Takashi Nagai, Miki Inoue
We report the case of a 7-year-old girl with intestinal obstruction due to post-traumatic intramural duodenal hematoma. She had fallen from the monkey bars the day before presenting to our hospital, and was admitted with signs of abdominal pain, vomiting, and nausea. Abdominal ultrasonography, computed tomography (CT), and magnetic resonance imaging (MRI) demonstrated a heterogeneous solid mass located within the duodenal wall, compressing the descending part of the duodenum. The inferior vena cava was also compressed by the mass lesion, although no associated symptoms were evident...
July 2016: Journal of Medical Ultrasonics
Mia T Lieberman, Lynn M Wachtman, Robert P Marini, Vasu Bakthavatchalu, James G Fox
A mature female squirrel monkey was noted during routine semiannual examinations to have moderate progressive weight loss. Serum chemistry panels revealed marked increases in hepatic enzyme, bilirubin, and bile salt concentrations and hypoalbuminemia. Abdominal ultrasonography revealed echogenic, shadowing debris in the gallbladder, consistent with cholelithiasis. At necropsy, marked thickening and distension of the gallbladder, cystic duct, and common bile duct was noted, and more than 50 irregularly shaped, black gallstones were removed from the biliary tract...
February 2016: Comparative Medicine
Yousuf S Jafarey, Christopher S Hanley, Ric A Berlinski, Connie Warner, Anthony Armstrong
A 13-yr-old female nulliparous Allen's swamp monkey (Allenopitchecus nigroviridis) presented with intermittent excessive vaginal bleeding, cyclical lethargy, and a history of irregular menstrual cycles. Abdominal ultrasonography revealed a subjectively thickened, irregular endometrium, multiple leiomyomata (uterine fibroids), and bilateral anechoic foci on the ovaries. Treatment was initiated with leuprolide acetate i.m. monthly for 6 mo. Recheck ultrasound at 3 mo showed a decrease in leiomyoma diameter and no evidence of active follicles on the ovaries...
December 2015: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Liangjing Yang, Junchen Wang, Takehiro Ando, Akihiro Kubota, Hiromasa Yamashita, Ichiro Sakuma, Toshio Chiba, Etsuko Kobayashi
BACKGROUND: Surgical navigation technology directed at fetoscopic procedures is relatively underdeveloped compared with other forms of endoscopy. The narrow fetoscopic field of views and the vast vascular network on the placenta make examination and photocoagulation treatment of twin-to-twin transfusion syndrome challenging. Though ultrasonography is used for intraoperative guidance, its navigational ability is not fully exploited. This work aims to integrate 3D ultrasound imaging and endoscopic vision seamlessly for placental vasculature mapping through a self-contained framework without external navigational devices...
September 2016: Surgical Endoscopy
Earl L Smith, Li-Fang Hung, Baskar Arumugam, Brien A Holden, Maureen Neitz, Jay Neitz
PURPOSE: Differences in the spectral composition of lighting between indoor and outdoor scenes may contribute to the higher prevalence of myopia in children who spend low amounts of time outdoors. Our goal was to determine whether environments dominated by long-wavelength light promote the development of myopia. METHODS: Beginning at 25 ± 2 days of age, infant monkeys were reared with long-wavelength-pass (red) filters in front of one (MRL, n = 6) or both eyes (BRL, n = 7)...
October 2015: Investigative Ophthalmology & Visual Science
P Michael Iuvone, Rashidul Haque, Alcides Fernandes, Scott R Lambert
Neonatal aphakia is associated with retardation of the axial elongation of the neonatal eye. In contrast, form deprivation increases axial elongation, an effect that has been associated with decreased retinal dopamine metabolism. The present investigation was conducted to test the hypothesis that neonatal aphakia induces an effect on the levels of retinal dopamine opposite to form deprivation. Lensectomy and vitrectomy were performed on the right eyes of rhesus monkeys at approximately 1 week of age; their left eyes were unmanipulated...
November 2015: Experimental Eye Research
Yifeng Wang, Ying Zhu, Ping Yu, Gaowen Chen, Baota Cai, Zhengguang Zhang, Na Liu, Xiaogang Lü, Juxiang Xiong, Lijuan Zhong, Junhua Rao
OBJECTIVE: To evaluate the surgical feasibility of uterine autologous transplantation in female cynomolgus monkeys and explore the effect of microsurgical technique. METHODS: From May 2011 to March 2014, 6 female cynomolgus monkeys, aged 7 to 12 years, were randomly divided into 2 surgical groups. In group A, gross surgeries were performed with naked eyes. In group B, uterine re-transplantation was performed under 10-time-magnifying microscopy. Anatomical data and operative durations were recorded and analyzed...
December 23, 2014: Zhonghua Yi Xue za Zhi [Chinese medical journal]
K Spanos, M De Maeseneer, A Nicolaides, A D Giannoukas
AIM: Venous training in Europe is lacking a formal curriculum among various specialties related to management of venous diseases. We conducted a survey in order to have a snapshot on the actual education and training level among physicians practicing currently venous surgery and phlebology in Europe. METHODS: From April 7, 2014 to June 11, 2014 a survey was carried out using the Survey Monkey system, including 11 main questions covering all the domains of training and education in venous surgery and phlebology...
April 2015: International Angiology: a Journal of the International Union of Angiology
Baskar Arumugam, Li-Fang Hung, Chi-Ho To, Brien Holden, Earl L Smith
PURPOSE: We investigated the effects of two simultaneously imposed, competing focal planes on refractive development in monkeys. METHODS: Starting at 3 weeks of age and continuing until 150 ± 4 days of age, rhesus monkeys were reared with binocular dual-focus spectacle lenses. The treatment lenses had central 2-mm zones of zero power and concentric annular zones with alternating powers of +3.0 diopter [D] and plano (pL or 0 D) (n = 7; +3D/pL) or -3.0 D and plano (n = 7; -3D/pL)...
November 2014: Investigative Ophthalmology & Visual Science
L Yang, J Wang, T Ando, A Kubota, H Yamashita, I Sakuma, T Chiba, E Kobayashi
This work introduces a self-contained framework for endoscopic camera tracking by combining 3D ultrasonography with endoscopy. The approach can be readily incorporated into surgical workflows without installing external tracking devices. By fusing the ultrasound-constructed scene geometry with endoscopic vision, this integrated approach addresses issues related to initialization, scale ambiguity, and interest point inadequacy that may be faced by conventional vision-based approaches when applied to fetoscopic procedures...
March 2015: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
M C Peluffo, J Stanley, N Braeuer, A Rotgeri, K-H Fritzemeier, U Fuhrmann, B Buchmann, T Adevai, M J Murphy, M B Zelinski, B Lindenthal, J D Hennebold, R L Stouffer
STUDY QUESTION: Can administration of a prostaglandin (PG) E2 receptor 2 (PTGER2) antagonist prevent pregnancy in adult female monkeys by blocking periovulatory events in the follicle without altering menstrual cyclicity or general health? SUMMARY ANSWER: This is the first study to demonstrate that a PTGER2 antagonist can serve as an effective non-hormonal contraceptive in primates. WHAT IS KNOWN ALREADY: The requirement for PGE2 in ovulation and the release of an oocyte surrounded by expanded cumulus cells (cumulus-oocyte expansion; C-OE) was established through the generation of PTGS2 and PTGER2 null-mutant mice...
July 2014: Human Reproduction
Julia Deanehan, Rachel Gallagher, Rebecca Vieira, Jason Levy
We present a case of a 3-year-old girl brought to the emergency department for evaluation of limp after falling off the monkey bars 1 day prior. X-rays of the entire left lower extremity were normal with no evidence of fracture, dislocation, or effusion. Point-of-care ultrasound of the left hip demonstrated a hip effusion, which prompted further imaging, ultimately revealing an occult fracture of the left proximal femoral metaphysis. This case demonstrates the ability of point-of-care ultrasound to guide the management of patients presenting to the pediatric emergency department with musculoskeletal complaints...
April 2014: Pediatric Emergency Care
Nancy C Boedeker, Philip Guzzetta, Steven L Rosenthal, Luis R Padilla, Suzan Murray, Kurt Newman
A 10-y-old ovariohysterectomized ring-tailed lemur (Lemur catta) was presented for exacerbation of respiratory signs. The lemur had a history of multiple examinations for various problems, including traumatic lacerations and recurrent perivulvar dermatitis. Examination revealed abnormal lung sounds and a femoral arteriovenous fistula with a palpable thrill and auscultable bruit in the right inguinal area. A diagnosis of congestive heart failure was made on the basis of exam findings, radiography, abdominal ultrasonography, and echocardiography...
February 2014: Comparative Medicine
Iori Kisu, Makoto Mihara, Kouji Banno, Hisako Hara, Yohei Masugi, Jun Araki, Takuya Iida, Yohei Yamada, Yojiro Kato, Takashi Shiina, Nobuhiko Suganuma, Daisuke Aoki
AIM: Uterine transplantation (UTx) is a potential option for child-bearing in women with uterine infertility. Recovery of uterine function after allogeneic UTx in non-human primates has not been reported. The objective of this study is to establish the functional uterine transplant model in non-human primates. METHODS: Uteri of two cynomolgus monkeys were simultaneously removed, cooled at 4°C and perfused with heparin saline. The uteri were interchanged with each other and then orthotopically transplanted...
April 2014: Journal of Obstetrics and Gynaecology Research
Rui Liu, Min Hu, Ji C He, Xing-Tao Zhou, Jin-Hui Dai, Xiao-Mei Qu, Hong Liu, Ren-Yuan Chu
PURPOSE: Influence of longitudinal chromatic aberration (LCA) on emmetropization during early eye development has not been studied in primates. We investigated the effects of quasi-monochromatic lighting on refractive development and eye growth in rhesus monkeys. METHODS: Infant rhesus monkeys were raised under one of three lighting conditions for 51 weeks: quasi-monochromatic blue light (peak 455 nm), red light (peak 610 nm), and white light (color temperature 5000 K)...
March 2014: Investigative Ophthalmology & Visual Science
Fabrice Marquet, Tobias Teichert, Shih-Ying Wu, Yao-Sheng Tung, Matthew Downs, Shutao Wang, Cherry Chen, Vincent Ferrera, Elisa E Konofagou
The delivery of drugs to specific neural targets faces two fundamental problems: (1) most drugs do not cross the blood-brain barrier, and (2) those that do, spread to the entire brain. To date, there exists only one non-invasive methodology with the potential to solve these problems: selective blood-brain barrier (BBB) opening using micro-bubble enhanced focused ultrasound. We have recently developed a single-element 500-kHz spherical transducer ultrasound setup for targeted BBB opening in the non-human primate that does not require simultaneous MRI monitoring...
2014: PloS One
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