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https://www.readbyqxmd.com/read/27911476/nd-yag-and-pulsed-dye-laser-therapy-in-infantile-hemangiomas-a-retrospective-analysis-of-271-treated-hemangiomas-in-149-children
#1
F Hartmann, A Lockmann, L-L Grönemeyer, H A Haenssle, M Zutt, H von Fintel, I Kühnle, M P Schön, K-M Thoms
BACKGROUND: Infantile hemangiomas (IH) are common benign tumors in infancy. Most IH resolve spontaneously, but some require treatment due to ulceration, functional impairment or cosmetic disfiguration. While systemic propranolol is effective in many cases, laser therapy may be a safe topical alternative. OBJECTIVE: To assess the efficacy of combined Nd:YAG/pulsed dye laser (PDL) or PDL alone for therapy of IH. PATIENTS AND METHODS: 271 IH in 149 infants were treated with combined Nd:YAG/PDL or PDL alone...
December 2, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27911447/the-enlarged-extraocular-muscle-to-relax-reflect-or-refer
#2
F Shafi, P Mathewson, P Mehta, H S Ahluwalia
PurposeExtraocular muscle enlargement (EOME) is most commonly associated with thyroid eye disease, but there are other causes. We report our outcomes of investigating and managing non-thyroid-related EOME (NTR-EOME).MethodsRetrospective consecutive case series. Sixteen patients identified by clinical features and orbital imaging. Patient demographics, radiological features, and adjuvant tests including biopsy and final diagnosis were recorded.ResultsMean age at presentation 59.3 years (range 24-89 years). Mean follow-up 3...
December 2, 2016: Eye
https://www.readbyqxmd.com/read/27911299/chronotropic-response-and-cognitive-function-in-a-cohort-at-risk-for%C3%A2-alzheimer-s-disease
#3
Lena L Law, Stephanie A Schultz, Elizabeth A Boots, Jean A Einerson, Ryan J Dougherty, Jennifer M Oh, Claudia E Korcarz, Dorothy F Edwards, Rebecca L Koscik, N Maritza Dowling, Catherine L Gallagher, Barbara B Bendlin, Cynthia M Carlsson, Sanjay Asthana, Bruce P Hermann, Mark A Sager, Sterling C Johnson, Dane B Cook, James H Stein, Ozioma C Okonkwo
The objective of this study was to examine the association of chronotropic response (CR) and heart rate (HR) recovery- two indices of cardiovascular function within the context of a graded exercise test- with cognitive performance in a cognitively healthy, late-middle-aged cohort at risk for Alzheimer's disease (AD). Ninety participants (age = 63.52±5.86 years; 65.6% female) from the Wisconsin Registry for Alzheimer's Prevention participated in this study. They underwent graded exercise testing and a comprehensive neuropsychological assessment that assessed the following four cognitive domains: Immediate Memory, Verbal & Learning Memory, Working Memory, and Speed & Flexibility...
December 1, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27911231/systematic-review-of-ventricular-peritoneal-shunt-and-percutaneous-endoscopic-gastrostomy-a-safe-combination
#4
Leendert H Oterdoom, D L Marinus Oterdoom, Johannes C F Ket, J Marc C van Dijk, Pieter Scholten
OBJECTIVE Various international and national gastrointestinal guidelines take different positions on whether ventriculoperitoneal shunt (VPS) insertion is a contraindication to percutaneous endoscopic gastrostomy (PEG). The objective of this meta-analysis was to try to answer the question of whether VPS insertion is a contraindication to PEG. METHODS A systematic review of the literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Electronic databases PubMed and Embase were searched using variations of the terms "ventriculo-peritoneal shunt" and "percutaneous (endoscopic) gastrostomy...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27911046/verticillium-dahliae-lysm-effectors-differentially-contribute-to-virulence-on-plant-hosts
#5
Anja Kombrink, Hanna Rovenich, Xiaoqian Shi-Kunne, Eduardo Rojas-Padilla, Grardy C M van den Berg, Emmanouil Domazakis, Ronnie de Jonge, Dirk-Jan Valkenburg, Andrea Sánchez-Vallet, Michael F Seidl, Bart P H J Thomma
Chitin-binding LysM effectors contribute to virulence of various plant pathogenic fungi that are causal agents of foliar diseases. Here, we report on LysM effectors of the soil-borne fungal vascular wilt pathogen Verticillium dahliae. Comparative genomics revealed three core LysM effectors that are conserved in a collection of V. dahliae strains. Remarkably, and in contrast to the previously studied LysM effectors of other plant pathogens, no expression of core LysM effectors was monitored in planta in a taxonomically diverse panel of host plants...
December 2, 2016: Molecular Plant Pathology
https://www.readbyqxmd.com/read/27911016/positive-impact-of-omalizumab-on-angioedema-and-quality-of-life-in-patients-with-refractory-chronic-idiopathic-spontaneous-urticaria-analyses-according-to-the-presence-or-absence-of-angioedema
#6
M Maurer, H Sofen, B Ortiz, F Kianifard, S Gabriel, J A Bernstein
BACKGROUND: Approximately 50% of patients with chronic idiopathic/spontaneous urticaria (CIU/CSU) report hives and angioedema; some experience hives/ angioedema only. OBJECTIVE: Assess omalizumab's effect on angioedema and quality of life (QoL) in subgroups with refractory CIU/CSU: those with and without angioedema. METHODS: Patients received omalizumab (75, 150 or 300 mg) or placebo every 4 weeks for 12/24 weeks. Angioedema and QoL was assessed (Urticaria Patient Daily Diary and Dermatology Quality of Life Index [DLQI])...
December 2, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27910989/catalytic-asymmetric-aldol-addition-reactions-of-3-fluoro-indolinone-derived-enolates
#7
Lijun Zhang, Wenzhong Zhang, Haibo Mei, Jianlin Han, Vadim A Soloshonok, Yi Pan
Reported herein is a Cu(i)/bisoxazoline ligand-catalyzed aldol reaction of unprotected tertiary enolates generated in situ from 3-(1,1-dihydroxy-2,2,2-trifluoroethyl)-substituted derivatives of 3-fluoro-2-oxindoles. A range of α-fluoro-β-aryl/hetaryl/alkyl-β-hydroxy-indolin-2-ones containing C-F quaternary stereogenic centers of high pharmaceutical importance were furnished in good yields and satisfactory diastereo- and enantioselectivities. The reactions were conducted under operationally convenient conditions and displayed wide substrate/functional group generality including unprotected N-H on the tertiary enolates, and aromatic, hetero-aromatic and aliphatic aldehydes...
December 2, 2016: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/27910985/uvb-radiation-vitamin-d-and-multiple-sclerosis
#8
H F DeLuca, L Plum
Acheson et al. (1960) observed an inverse relationship between sunlight exposure and the incidence of Multiple Sclerosis (MS). This led to the suggestion that increased levels of vitamin D caused by sunlight in some way suppresses MS. Further, super physiological doses of the metabolically active metabolite of vitamin D, i.e. 1α,25 dihydroxy vitamin D suppresses the animal model of MS i.e. experimental autoimmune encephalomyelitis (EAE). However, this response was accompanied by hypercalcemia. Hypercalcemia itself can suppress EAE...
December 2, 2016: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/27910843/unique-thermodynamic-relationships-for-%C3%AE-fh-o-and-%C3%AE-fg-o-for-crystalline-inorganic-salts-i-predicting-the-possible-existence-and-synthesis-of-na2so2-and-na2seo2-addendum
#9
Ángel Vegas, Joel F Liebman, H Donald Brooke Jenkins
Addendum to Vegas et al. [(2012), Acta Cryst. B68, 511-527].
December 1, 2016: Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
https://www.readbyqxmd.com/read/27910842/comparison-of-hydrogen-bonds-and-diverse-weak-interactions-of-the-nitro-group-in-2-methyl-4-nitroanilinium-nitrate-bisulfate-and-two-hexafluoridosilicates-elementary-graph-set-approach
#10
Marek Daszkiewicz, Agnieszka Mielcarek
Crystal structures of (H2m4na)NO3 (1), (H2m4na)HSO4 (2), (H2m4na)2SiF6 (3) and (H2m4na)2SiF6·2H2O (4), where 2m4na = 2-methyl-4-nitroaniline, are presented. Two layers of interactions occur in the structures, N-H...O/F hydrogen bonds and interactions with the nitro group. Although diverse, hydrogen-bonding patterns are compared with each other by means of interrelations among elementary graph-set descriptors and descriptors of hydrogen-bonding patterns. Using mathematical relations, the gradual expansion of the ring patterns was shown in the crystal structures...
December 1, 2016: Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
https://www.readbyqxmd.com/read/27910833/cu-ii-and-zn-ii-%C3%AE-diketonate-coordination-polymers-based-on-pyrimidin-2-amine-pyrazine-and-1-2-bis-4-pyridyl-ethane
#11
Franc Perdih
Copper(II) and zinc(II) bis(4,4,4-trifluoro-1-phenylbutane-1,3-dionato) compounds with pyrimidin-2-amine (pyr2a), pyrazine (pyz) and 1,2-bis(4-pyridyl)ethane (dpet) were prepared and solid-state structures of coordination polymers [M(tfpb)2(pyr2a)]∞ [M = Cu (1), Zn (2); tfpb = 4,4,4-trifluoro-1-phenylbutane-1,3-dionate], [M(tfpb)2(pyz)]∞ [M = Cu (3), Zn (4a, 4b)] and [Cu(tfpb)2(dpet)]∞ (5), respectively, were determined by single-crystal X-ray analysis. The coordination of metal centers in all compounds is octahedral with nitrogen ligands occupying the axial positions...
December 1, 2016: Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials
https://www.readbyqxmd.com/read/27910823/optimized-mlaa-for-quantitative-non-tof-pet-mr-of-the-brain
#12
Didier Benoit, Claes N Ladefoged, Ahmadreza Rezaei, Sune H Keller, Flemming L Andersen, Liselotte Højgaard, Adam E Hansen, Søren Holm, Johan Nuyts
For quantitative tracer distribution in positron emission tomography, attenuation correction is essential. In a hybrid PET/CT system the CT images serve as a basis for generation of the attenuation map, but in PET/MR, the MR images do not have a similarly simple relationship with the attenuation map. Hence attenuation correction in PET/MR systems is more challenging. Typically either of two MR sequences are used: the Dixon or the ultra-short time echo (UTE) techniques. However these sequences have some well-known limitations...
December 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27910712/development-of-a-nanogel-formulation-for-transdermal-delivery-of-tenoxicam-a-pharmacokinetic-pharmacodynamic-modeling-approach-for-quantitative-prediction-of-skin-absorption
#13
Mohammed H Elkomy, Shahira F El Menshawe, Hussein M Eid, Ahmed M A Ali
This study investigates potentials of solid lipid nanoparticles (SLN) based gel for transdermal delivery of tenoxicam (TNX) and describes a pharmacokinetics-pharmacodynamics (PK-PD) modeling approach for predicting concentration-time profile in skin. A 2(3) factorial design was adopted to study the effect of formulation factors on SLN properties and determine the optimal formulation. SLN-gel tolerability was investigated using rabbit skin irritation test. Its anti-inflammatory activity was assessed by carrageenan induced rat paw edema test...
December 2, 2016: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/27910696/a-new-setup-for-localized-implantation-and-live-characterization-of-kev-energy-multiply-charged-ions-at-the-nanoscale
#14
S Guillous, C Bourin, B Ban D'Etat, A Benyagoub, A Cassimi, C Feierstein, E Gardés, E Giglio, S Girard, C Grygiel, A Houel, H Lebius, A Méry, I Monnet, J-M Ramillon, J Rangama, F Ropars, E Verzeroli, M Viteau, A Delobbe
An innovative experimental setup, PELIICAEN, allowing the modification of materials and the study of the effects induced by multiply charged ion beams at the nanoscale is presented. This ultra-high vacuum (below 5 × 10(-10) mbar) apparatus is equipped with a focused ion beam column using multiply charged ions and a scanning electron microscope developed by Orsay Physics, as well as a scanning probe microscope. The dual beam approach coupled to the scanning probe microscope achieves nanometer scale in situ topological analysis of the surface modifications induced by the ion beams...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910673/implementation-of-the-new-multichannel-x-mode-edge-density-profile-reflectometer-for-the-icrf-antenna-on-asdex-upgrade
#15
D E Aguiam, A Silva, V Bobkov, P J Carvalho, P F Carvalho, R Cavazzana, G D Conway, O D'Arcangelo, L Fattorini, H Faugel, A Fernandes, H Fünfgelder, B Gonçalves, L Guimarais, G De Masi, L Meneses, J M Noterdaeme, R C Pereira, G Rocchi, J M Santos, A A Tuccillo, O Tudisco
A new multichannel frequency modulated continuous-wave reflectometry diagnostic has been successfully installed and commissioned on ASDEX Upgrade to measure the plasma edge electron density profile evolution in front of the Ion Cyclotron Range of Frequencies (ICRF) antenna. The design of the new three-strap ICRF antenna integrates ten pairs (sending and receiving) of microwave reflectometry antennas. The multichannel reflectometer can use three of these to measure the edge electron density profiles up to 2 × 10(19) m(-3), at different poloidal locations, allowing the direct study of the local plasma layers in front of the ICRF antenna...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910656/the-design-of-the-optical-thomson-scattering-diagnostic-for-the-national-ignition-facility
#16
P S Datte, J S Ross, D H Froula, K D Daub, J Galbraith, S Glenzer, B Hatch, J Katz, J Kilkenny, O Landen, D Manha, A M Manuel, W Molander, D Montgomery, J Moody, G F Swadling, J Weaver
The National Ignition Facility (NIF) is a 192 laser beam facility designed to support the Stockpile Stewardship, High Energy Density and Inertial Confinement Fusion (ICF) programs. We report on the design of an Optical Thomson Scattering (OTS) diagnostic that has the potential to transform the community's understanding of NIF hohlraum physics by providing first principle, local, time-resolved measurements of under-dense plasma conditions. The system design allows operation with different probe laser wavelengths by manual selection of the appropriate beam splitter and gratings before the shot...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910640/calibration-of-the-microcalorimeter-spectrometer-on-board-the-hitomi-astro-h-observatory-invited
#17
M E Eckart, K R Boyce, G V Brown, M P Chiao, R Fujimoto, D Haas, J-W den Herder, Y Ishisaki, R L Kelley, C A Kilbourne, M A Leutenegger, D McCammon, K Mitsuda, F S Porter, M Sawada, G A Sneiderman, A E Szymkowiak, Y Takei, M Tashiro, M Tsujimoto, C P de Vries, T Watanabe, S Yamada, N Y Yamasaki
The Hitomi Soft X-ray Spectrometer (SXS) was a pioneering non-dispersive imaging x-ray spectrometer with 5 eV FWHM energy resolution, consisting of an array of 36 silicon-thermistor microcalorimeters at the focus of a high-throughput soft x-ray telescope. The instrument enabled astrophysical plasma diagnostics in the 0.3-12 keV band. We introduce the SXS calibration strategy and corresponding ground calibration measurements that took place from 2012-2015, including both the characterization of the microcalorimeter array and measurements of the x-ray transmission of optical blocking filters...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910629/fast-island-phase-identification-for-tearing-mode-feedback-control-on-j-text-tokamak
#18
B Rao, D Li, F R Hu, Y H Ding, Q M Hu, H Jin
A new method to control the tearing mode (TM) in tokamaks has been proposed [Q. Hu and Q. Yu, Nucl. Fusion 56, 034001 (5pp.) (2016)], according to which, the external resonant magnetic perturbation needs to be applied in certain magnetic island phase regions. Therefore, it is very important to identify the helical phase of magnetic islands in real time. The TM in tokamak plasmas is normally rotating and carries magnetic oscillations, which are known as Mirnov oscillations and can be detected by Mirnov probes...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910626/a-high-resolving-power-x-ray-spectrometer-for-the-omega-ep-laser-invited
#19
P M Nilson, F Ehrne, C Mileham, D Mastrosimone, R K Jungquist, C Taylor, C R Stillman, S T Ivancic, R Boni, J Hassett, D J Lonobile, R W Kidder, M J Shoup, A A Solodov, C Stoeckl, W Theobald, D H Froula, K W Hill, L Gao, M Bitter, P Efthimion, D D Meyerhofer
A high-resolving-power x-ray spectrometer has been developed for the OMEGA EP Laser System based on a spherically bent Si [220] crystal with a radius of curvature of 330 mm and a Spectral Instruments (SI) 800 Series charge-coupled device. The instrument measures time-integrated x-ray emission spectra in the 7.97- to 8.11-keV range, centered on the Cu Kα1 line. To demonstrate the performance of the spectrometer under high-power conditions, Kα1,2 emission spectra were measured from Cu foils irradiated by the OMEGA EP laser with 100-J, 1-ps pulses at focused intensities above 10(18) W/cm(2)...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27910615/measurement-of-diagnostic-neutral-beam-parameters-on-j-text
#20
J R Wang, Z F Cheng, Z Li, Y Li, J Luo, X L Zhang, G Zhuang
A Doppler frequency shift spectrum (DFSS) system composed of two spectrometers has been developed for the joint Texas experimental tokamak to measure diagnostic neutral beam parameters including the beam energy fractions, intensity distributions, and divergences. The beam energy fractions are derived from measurements of H-alpha (Hα) emission using collisional excitation cross sections. The beam intensity distributions are obtained using an 11-channel measurement with a reconstruction technique. The beam divergences are obtained from spectrum broadening and geometric calculations...
November 2016: Review of Scientific Instruments
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