keyword
https://read.qxmd.com/read/38508535/integrative-model-based-comparison-of-target-site-specific-antimicrobial-effects-a-case-study-with-ceftaroline-and-lefamulin
#21
JOURNAL ARTICLE
Wisse van Os, Anh Duc Pham, Sabine Eberl, Iris K Minichmayr, J G Coen van Hasselt, Markus Zeitlinger
OBJECTIVE: Predictions of antimicrobial effects typically rely on plasma-based pharmacokinetic-pharmacodynamic (PK-PD) targets, ignoring target-site concentrations and potential differences in tissue penetration between antibiotics. In this study, we applied PK-PD modelling to compare target site-specific effects of antibiotics by integrating clinical microdialysis data, in vitro time-kill curves, and antimicrobial susceptibility distributions. As a case study, we compared the effect of lefamulin and ceftaroline against methicillin-resistant Staphylococcus aureus (MRSA) at soft-tissue concentrations...
March 18, 2024: International Journal of Antimicrobial Agents
https://read.qxmd.com/read/38508461/unexpected-high-yield-of-acrolein-underlies-the-importance-of-the-hydrogen-abstraction-mechanism-in-photooxidation-of-allyl-methyl-sulfide-ams
#22
JOURNAL ARTICLE
Alejandro L Cardona, Mariano Teruel, Oscar N Ventura
This work explores theoretically the gas phase oxidation of allyl methyl sulfide (AMS, H2 CCHCH2 SCH3 ) initiated by • OH radicals, focusing on the H-abstraction pathway at the M06-2X-D3/aug-cc-pVTZ and MN15/aug-cc-pVTZ levels of theory (m06Tz and mn15Tz). The formation of a prereactive complex (PRC) is involved in H-abstraction processes with two potential directions of approach for the OH radical, denoted as "α" and "β". The PRCs, demonstrate increased reactivity, primarily due to the interaction between the sulfur atoms and the hydroxyl hydrogen...
March 18, 2024: Chemosphere
https://read.qxmd.com/read/38508384/decompression-alone-versus-interspinous-interlaminar-device-placement-for-degenerative-lumbar-pathologies-systematic-review-and-meta-analysis
#23
REVIEW
Zach Pennington, Nikita Lakomkin, Anthony L Mikula, Aladine A Elsamadicy, Maria Astudillo Potes, Jeremy L Fogelson, Andrew J Grossbach, Benjamin D Elder
INTRODUCTION: Interspinous (ISD) and interlaminar devices (ILD) are marketed as alternatives to conventional surgery for degenerative lumbar pathologies; comparisons to decompression-alone are limited. The present study reviews the extant literature comparing cost and effectiveness of ISDs/ILDs to decompression-alone. METHODS: Articles comparing decompression-alone to ISD/ILD were identified; outcomes of interest included general and disease-specific patient-reported outcomes (PROs), perioperative complications, and total treatment costs...
March 18, 2024: World Neurosurgery
https://read.qxmd.com/read/38507085/long-term-outcomes-of-congenital-tracheal-stenosis-after-slide-tracheoplasty
#24
JOURNAL ARTICLE
Taichi Nakatani, Keiichi Morita, Akiko Yokoi, Tadashi Hatakeyama
PURPOSE: Long-term outcomes of slide tracheoplasty in patients with congenital tracheal stenosis (CTS) have rarely been reported. This study aimed to clarify the long-term outcomes of CTS after slide tracheoplasty. METHODS: The medical records of 33 patients who underwent slide tracheoplasty for CTS at our institution between January 2005 and July 2018, with a follow-up duration > 5 years, were retrospectively reviewed. Patients' characteristics, perioperative condition, operative management, postoperative course, tracheal stenosis rates and growth data, were collected from medical records...
March 20, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38506684/do-patients-accurately-recall-pain-levels-following-sacroiliac-joint-steroid-injection-a-cohort-study-of-recall-bias-in-patient-reported-outcomes
#25
JOURNAL ARTICLE
Davin C Gong, Aditya Muralidharan, Bilal B Butt, Ronald Wasserman, Joshua D Piche, Rakesh D Patel, Ilyas Aleem
BACKGROUND: Sacroiliac joint (SIJ) injections are crucial in the diagnostic toolkit for evaluating SIJ pathology. Recall bias is an important component in patient-reported outcomes that has not been well studied in SIJ injection. OBJECTIVE: The purpose of this study was to characterize the accuracy, direction, and magnitude of pain level recall bias following SIJ steroid injection and study the factors that affect patient recollection. STUDY DESIGN: Prospective cohort study...
March 2024: Pain Physician
https://read.qxmd.com/read/38506516/the-modern-alchemy-of-clinical-pathology-turning-the-output-of-microbiology-laboratory-operations-into-gold
#26
REVIEW
Sanjat Kanjilal
The clinical microbiology laboratory generates a huge amount of high-quality data that play a vital role in clinical care. With proper extraction, cleaning, analysis, and validation pipelines, these data can serve multiple other purposes that include supporting laboratory operations, understanding local epidemiology, informing hospital-specific policies, and public health surveillance. In this review, I use one of the core activities of the microbiology laboratory, antimicrobial susceptibility testing (AST), to illustrate several potential applications of next-generation data analytics...
March 20, 2024: Journal of Clinical Microbiology
https://read.qxmd.com/read/38506256/alcohol-health-loss-and-mortality-can-wine-really-save-the-good-name-of-moderate-alcohol-consumption
#27
JOURNAL ARTICLE
Stanisław Surma, Grzegorz Gajos
It is estimated that one third of the world's population consumes alcohol. At the same time, it is well-known that excessive alcohol consumption in one of the leading causes of premature mortality. The history of production of alcoholic beverages, especially wine, date as long as 8000 years ago. However, humans soon realized adverse effects of alcohol abuse and tried to limit its consumption. Higher alcohol consumption is associated with health loss and increased risk of all-cause mortality. It is linearly associated with a higher risk of many types of cancers, liver disease, incidence of atrial fibrillation, hemorrhagic stroke, heart failure...
March 20, 2024: Polish Archives of Internal Medicine
https://read.qxmd.com/read/38502265/investigation-of-fire-regime-dynamics-and-modeling-of-burn-area-over-india-for-the-twenty-first-century
#28
JOURNAL ARTICLE
Somnath Bar, Prasenjit Acharya, Bikash Ranjan Parida, Srikanta Sannigrahi, Arabinda Maiti, Gunadhar Barik, Navneet Kumar
The characteristics of the vegetation fire (VF) regime are strongly influenced by geographical variables such as regional physiographic settings, location, and climate. Understanding the VF regime is extremely important for managing and mitigating the impacts of fires on ecosystems, communities, and human activities in forest fire-prone regions. The present study thereby aimed to explore the potential effects of the confounding factors on VF in India to offer actionable and achievable solutions for mitigating this concurring environmental issue sustainably...
March 19, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38501708/outcomes-of-tibiotalocalcaneal-arthrodesis-vs-talar-body-prosthesis-as-treatment-of-collapsed-avascular-necrosis-of-the-talus-a-10-to-13-year-follow-up-retrospective-comparative-study
#29
JOURNAL ARTICLE
Thos Harnroongroj, Marut Arunakul, Pissanu Reingrittha, Bavornrit Chuckpaiwong, Chayanin Angthong, Theerawoot Tharmviboonsri, Penpun Lertwattanachai
BACKGROUND: Joint salvage surgeries such as tibiotalocalcaneal arthrodesis and talar prosthesis are commonly used in the surgical treatment of collapsed avascular necrosis of the talus (AVNT). However, differences in outcomes of these 2 surgical treatments are still inconclusive. This study compared the 10- to 13-year outcomes and 10-year survivorship rates of tibiotalocalcaneal arthrodesis and talar body prosthesis in the surgical treatment of collapsed AVNT. METHODS: A retrospective comparative study was conducted of patients who underwent either tibiotalocalcaneal arthrodesis or talar body prosthesis implantation between 2005 and 2012...
March 19, 2024: Foot & Ankle International
https://read.qxmd.com/read/38500506/influenza-and-covid-19-co-infection-and-vaccine-effectiveness-against-severe-cases-a-mathematical-modeling-study
#30
JOURNAL ARTICLE
Jingyi Liang, Yangqianxi Wang, Zhijie Lin, Wei He, Jiaxi Sun, Qianyin Li, Mingyi Zhang, Zichen Chang, Yinqiu Guo, Wenting Zeng, Tie Liu, Zhiqi Zeng, Zifeng Yang, Chitin Hon
BACKGROUND: Influenza A virus have a distinctive ability to exacerbate SARS-CoV-2 infection proven by in vitro studies. Furthermore, clinical evidence suggests that co-infection with COVID-19 and influenza not only increases mortality but also prolongs the hospitalization of patients. COVID-19 is in a small-scale recurrent epidemic, increasing the likelihood of co-epidemic with seasonal influenza. The impact of co-infection with influenza virus and SARS-CoV-2 on the population remains unstudied...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38498474/the-invasive-weed-trianthema-portulacastrum-in-israel
#31
JOURNAL ARTICLE
Yaakov Goldwasser, Onn Rabinowitz, Guy Achdary, Omer Kapiluto, Jackline Abu-Nasser, Evgeny Smirnov, Hanan Eizenberg
Trianthema portulacastrum L. (Aizoaceae), commonly known as desert horse purslane or black pigweed, is a C4 dicot succulent annual herb that is widespread in Southeast Asia, tropical America, Africa, and Australia. In Israel, it is an invasive weed of increasing importance in agricultural fields. The aim of this study was to investigate the biology of this invasive weed and its spread in the Hula Valley of Israel. Initial studies included the investigation of the T. portulacastrum specimens held at the Israel National Herbarium...
February 14, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38497765/update-of-the-minimum-information-about-biobank-data-sharing-miabis-core-terminology-to-the-3-rd-version
#32
JOURNAL ARTICLE
Niina Eklund, Cäcilia Engels, Michael Neumann, Andrzej Strug, Esther van Enckevort, Ronny Baber, Margreet Bloemers, Annelies Debucquoy, Aad van der Lugt, Heimo Müller, Lauri Parkkonen, Philip R Quinlan, Esmond Urwin, Petr Holub, Kaisa Silander, Gabriele Anton
Introduction: The Minimum Information About BIobank Data Sharing (MIABIS) is a biobank-specific terminology enabling the sharing of biobank-related data for different purposes across a wide range of database implementations. After 4 years in use and with the first version of the individual-level MIABIS component Sample , Sample donor, and Event , it was necessary to revise the terminology, especially to include biobanks that work more in the data domain than with samples. Materials & Methods: Nine use-cases representing different types of biobanks, studies, and networks participated in the development work...
March 18, 2024: Biopreservation and Biobanking
https://read.qxmd.com/read/38495634/depression-scores-decrease-after-hip-arthroscopy-for-femoroacetabular-impingement-syndrome
#33
JOURNAL ARTICLE
Anthony J Zacharias, Matthew Dooley, Samuel Mosiman, Andrea M Spiker
PURPOSE: To evaluate clinical depression scores and functional outcomes following arthroscopic treatment of femoroacetabular impingement syndrome in patients with elevated preoperative depressive symptoms as defined by Patient-Reported Outcomes Measurement Information System for Depression (PROMIS-D). METHODS: Patients with femoroacetabular impingement syndrome completed the PROMIS-D Computer Adaptive Test and additional patient-reported outcome (PRO) measures preoperatively and at the time of postoperative visits...
April 2024: Arthroscopy, sports medicine, and rehabilitation
https://read.qxmd.com/read/38495186/numerical-entropy-analysis-of-mhd-electro-osmotic-flow-of-peristaltic-movement-in-a-nanofluid
#34
JOURNAL ARTICLE
M Gnaneswara Reddy, K Venugopal Reddy, Basma Souayeh, H Fayaz
The present study investigates the MHD electro-osmotic flow of entropy generation analysis for peristaltic movement in a nanofluid with temperature-dependent viscosity. Long wavelengths, i.e., The magnitude of a wave's energy corresponds directly to its frequency while being inversely related to its wavelength in terms of velocity, temperature, and concentration, govern and confine the flow stream in the laminar region. Ohmic heating and hall effects are also included. Graphs are used to obtain and examine numerical solutions for axial velocity, temperature, concentration, Bejan number, and entropy generation...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38493855/salinity-mediated-enhancement-of-quaternary-ammonium-compounds-resistance-and-removal-in-endophytic-bacteria-lse01
#35
JOURNAL ARTICLE
Xiao Xiao, Junjie Li, Xiaotong Wang, Lin Ding, Shengju Shen, Ting Liu, Zhong Ren, Xubiao Luo
The widespread usage of quaternary ammonium compounds (QACs) as disinfectants during the COVID-19 pandemic poses significant environmental risks, such as toxicity to organisms and the emergence of superbugs. In this study, different inorganic salts (NaCl, KCl, CaCl2 , MgCl2 ) were used to induce endophytes LSE01 isolated from hyperaccumulating plants. After five generations of cultivation under 80 g/L NaCl, the minimum inhibitory concentration (MIC) of LSE01 to QACs increased by about 3-fold, while its degradation extent increased from 8% to 84% for C12 BDMA-Cl and 5%-89% for C14 BDMA-Cl...
March 15, 2024: Environmental Research
https://read.qxmd.com/read/38493263/effective-social-spider-optimization-algorithms-for-distributed-assembly-permutation-flowshop-scheduling-problem-in-automobile-manufacturing-supply-chain
#36
JOURNAL ARTICLE
Weiwei Zhang, Jianhua Hao, Fangai Liu
This paper presents a novel distributed assembly permutation flowshop scheduling problem (DAPFSP) based on practical problems in automobile production. Different from the existing research on DAPFSP, this study considers that each component of the final product is composed of more than one part. Components are processed in a set of identical components manufacturing factories and are assembled into products in the assembly factory. The integration of manufacturing processes is an important objective of Industry 4...
March 16, 2024: Scientific Reports
https://read.qxmd.com/read/38493082/associations-of-physical-activity-intensity-frequency-duration-and-volume-with-the-incidence-of-sarcopenia-in-middle-aged-and-older-adults-a-4-year-longitudinal-study-in-china
#37
JOURNAL ARTICLE
Xiaoguang Zhao, Dongxue Liu, Hongjun Zhang, Shaoshuai Shen, Naipeng Zhang, Yihan Pan, Chao Fu, Wenjiao Wang, Hang Ren, Xiaopeng Pan
BACKGROUND: Physical activity (PA) plays an important role in the process of several chronic diseases. It may be also associated with the incidence of sarcopenia. This study aimed to determine the association of PA from different components including frequency, duration, intensity, and volume with the incidence of sarcopenia in middle-aged and older adults. METHODS: This study used data from the China Health and Retirement Longitudinal Study in 2011 and 2015. A total of 3,760 individuals aged ≥ 40 years were involved in this study...
March 16, 2024: BMC Geriatrics
https://read.qxmd.com/read/38492629/primary-and-revision-reverse-total-shoulder-arthroplasty-using-a-patient-matched-glenoid-implant-for-severe-glenoid-bone-deficiency
#38
JOURNAL ARTICLE
Richard M Michelin, Isaac Manuputy, Rajesh Rangarajan, Brian K Lee, Mark Schultzel, John M Itamura
BACKGROUND: Severe glenoid bone loss in the setting of both primary and revision reverse total shoulder arthroplasty (rTSA) continues to remain a significant challenge. The purpose of this study was to report on radiographic and clinical outcomes of primary and revision rTSA using a patient-matched, 3-dimensionally printed metal glenoid implant to address severe glenoid bone deficiency. This is a follow-up study to previously reported preliminary results. METHODS: A retrospective review was performed on 62 patients with severe glenoid bone deficiency underwent either primary or revision rTSA using the Comprehensive Vault Reconstruction System (VRS) (Zimmer Biomet, Warsaw, IN, USA) at a single institution...
March 14, 2024: Journal of Shoulder and Elbow Surgery
https://read.qxmd.com/read/38490073/physical-function-and-activity-of-patients-after-open-abdominal-surgery-a-prospective-cohort-study-comparing-the-clinimetric-properties-of-two-outcome-measures
#39
JOURNAL ARTICLE
Marelee Fourie, Heleen van Aswegen
OBJECTIVES: To measure and compare the clinimetric properties of the Chelsea Critical Care Physical Assessment (CPAx) and Physical Function in Intensive Care Test-scored (PFIT-s) for assessment of physical function and activity. DESIGN: Prospective cohort design using crossover-randomisation of the sequence in which participants were assessed with CPAx and PFIT-s. SETTING: Surgical and transplant intensive care units (ICU) in an academic hospital...
February 10, 2024: Physiotherapy
https://read.qxmd.com/read/38487993/a-multidisciplinary-approach-to-identifying-and-managing-heterotopic-gastric-inlet-patches
#40
JOURNAL ARTICLE
L Ayres, S Perring, S A R Nouraei
INTRODUCTION: Gastric inlet patches are often incidental, but can also be a treatable cause of laryngo-esophageal symptoms. METHODS: We retrospectively reviewed all patients whose gastric inlet patches were diagnosed following assessment for laryngopharyngeal and swallowing symptoms. Improvement following Argon Plasma Coagulation (APC) was assessed using Minimum Clinically-Important Difference methodology combining voice, throat, and swallowing domains. Correlations between APC response and measures of reflux and mucosal barrier integrity, measured during 24-h pH-impedance manometry, were obtained...
March 15, 2024: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
keyword
keyword
108871
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.