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https://www.readbyqxmd.com/read/29774624/what-does-it-take-to-stress-a-word-digital-manipulation-of-stress-markers-in-ataxic-dysarthria
#1
Anja Lowit, Tolulope Ijitona, Anja Kuschmann, Stephen Corson, John Soraghan
BACKGROUND: Stress production is important for effective communication, but this skill is frequently impaired in people with motor speech disorders. The literature reports successful treatment of these deficits in this population, thus highlighting the therapeutic potential of this area. However, no specific guidance is currently available to clinicians about whether any of the stress markers are more effective than others, to what degree they have to be manipulated, and whether strategies need to differ according to the underlying symptoms...
May 18, 2018: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/29771855/does-multimodal-rehabilitation-for-ankle-instability-improve-patients-self-assessed-functional-outcomes-a-network-meta-analysis
#2
Konstantinos Tsikopoulos, Dimitris Mavridis, Dimitrios Georgiannos, Haris S Vasiliadis
BACKGROUND: Although there are many nonsurgical treatment options for the primary management of chronic ankle instability, the most effective nonoperative intervention has not been defined. QUESTIONS/PURPOSES: The purpose of this study was to perform a network meta-analysis to compare the results of different standalone and/or combined nonsurgical interventions on chronic ankle instability as measured by (1) the Cumberland Ankle Instability Tool (CAIT) at 0 to 6 months after treatment and (2) treatment-related complications...
June 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29766505/esophageal-multimodal-stimulation-and-sensation
#3
REVIEW
Dag Arne Lihaug Hoff, Barry McMahon, Hans Gregersen
Esophageal mechanosensation describes the relationship between a mechanical stimulation of the esophageal wall, such as bag distension, and the reaction to the stimulation perceived or unperceived. When studying mechanosensation in esophageal disease, it is important to recognize that symptoms might be due to alterations at different levels of the neuromuscular system, such as alterations at the mechanoreceptor level or in the afferent mechanosensory pathways, or irregularities in the homeostatic state. One might ask if it is possible to provoke, record, and describe the multidimensional responses behind a mechanosensory experience? It is a complex system and, at a minimum, a multidisciplinary approach is needed to avoid erroneous conclusions...
May 16, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29766371/landsat-phenological-metrics-and-their-relation-to-aboveground-carbon-in-the-brazilian-savanna
#4
M Schwieder, P J Leitão, J R R Pinto, A M C Teixeira, F Pedroni, M Sanchez, M M Bustamante, P Hostert
BACKGROUND: The quantification and spatially explicit mapping of carbon stocks in terrestrial ecosystems is important to better understand the global carbon cycle and to monitor and report change processes, especially in the context of international policy mechanisms such as REDD+ or the implementation of Nationally Determined Contributions (NDCs) and the UN Sustainable Development Goals (SDGs). Especially in heterogeneous ecosystems, such as Savannas, accurate carbon quantifications are still lacking, where highly variable vegetation densities occur and a strong seasonality hinders consistent data acquisition...
May 15, 2018: Carbon Balance and Management
https://www.readbyqxmd.com/read/29763524/separating-extreme-ph-gradients-using-amphiphilic-copolymer-membranes
#5
Lorena Ruiz-Pérez, Claire Hurley, Salvador Tomás, Giuseppe Battaglia
Polymeric vesicles, also called polymersomes, are highly efficient biomimetic systems. They can generate compartmentalized volumes at the nanoscale supported by synthetic amphiphilic membranes that closely mimic their biological counterparts. Membrane permeability and the ability to separate extreme pH gradients is a crucial condition a successful biomimetic system must meet. We show polymersomes formed by non-ionic polybutadiene-b-polyethylene oxide (PBd-b-PEO) amphiphilic block copolymers engineer robust and stable membranes that are able able to sustain pH gradients of 10 for a minimum of 8 days...
May 15, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/29761488/psychological-therapies-for-treatment-resistant-depression-in-adults
#6
REVIEW
Sharea Ijaz, Philippa Davies, Catherine J Williams, David Kessler, Glyn Lewis, Nicola Wiles
BACKGROUND: Antidepressants are a first-line treatment for adults with moderate to severe major depression. However, many people prescribed antidepressants for depression don't respond fully to such medication, and little evidence is available to inform the most appropriate 'next step' treatment for such patients, who may be referred to as having treatment-resistant depression (TRD). National Institute for Health and Care Excellence (NICE) guidance suggests that the 'next step' for those who do not respond to antidepressants may include a change in the dose or type of antidepressant medication, the addition of another medication, or the start of psychotherapy...
May 14, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29754757/-how-does-vaping-products-work
#7
REVIEW
C Bamberger, V Deiss, S Gros
To maximize the chances of replacing smoking with vaping, it is necessary to know the different types of existing devices, their characteristics and their most important settings as well as their influence on sensations. To support a user it is also important to understand the nature of the inhaled and exhaled vapor, as well as the possible mistakes that can lead to a less enjoyable experience. Highlighting e-liquids formulations and emissions can help understanding how a minimum of 95 % risk reduction compared to tobacco smoking is achieved and the influence of compounds on the user's experience...
May 10, 2018: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/29751849/effect-of-continuous-compression-stimulation-on-pressure-pain-threshold-and-muscle-spasms-in-older-adults-with-knee-osteoarthritis-a-randomized-trial
#8
Ryo Tanaka, Takuya Umehara, Yuuki Kawabata, Tomohiko Sakuda
OBJECTIVE: The purpose of this study was to assess the effect of continuous compression stimulation on pressure-pain threshold and muscle spasms in older adults with knee osteoarthritis. METHODS: Thirty-two older adults with knee osteoarthritis on outpatient visits were randomly divided into 2 groups. Those in the treatment group (n = 16) received 5-minute massage therapy (continuous compression stimulation), and those in the control group (n = 16) received sham massage therapy (touch without compression)...
May 2018: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29749912/comparative-durability-and-costs-analysis-of-ventricular-shunts
#9
Nitin Agarwal, Ahmed Kashkoush, Michael M McDowell, William R Lariviere, Naveed Ismail, Robert M Friedlander
OBJECTIVE Ventricular shunt (VS) durability has been well studied in the pediatric population and in patients with normal pressure hydrocephalus; however, further evaluation in a more heterogeneous adult population is needed. This study aims to evaluate the effect of diagnosis and valve type-fixed versus programmable-on shunt durability and cost for placement of shunts in adult patients. METHODS The authors retrospectively reviewed the medical records of all patients who underwent implantation of a VS for hydrocephalus at their institution over a 3-year period between August 2013 and October 2016 with a minimum postoperative follow-up of 6 months...
May 11, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29748758/how-to-accurately-predict-solution-phase-gold-nanostar-stability
#10
Wenjing Xi, Hoa T Phan, Amanda J Haes
Unwanted nanoparticle aggregation and/or agglomeration may occur when anisotropic nanoparticles are dispersed in various solvents and matrices. While extended Derjaguin-Landau-Verwey-Overbeek (DLVO) theory has been successfully applied to predict nanoparticle stability in solution, this model fails to accurately predict the physical stability of anisotropic nanostructures; thus limiting its applicability in practice. Herein, DLVO theory was used to accurately predict gold nanostar stability in solution by investigating how the choice of the nanostar dimension considered in calculations influences the calculated attractive and repulsive interactions between nanostructures...
May 11, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29748161/effects-of-contributor-experience-on-the-quality-of-health-related-wikipedia-articles
#11
Peter Holtz, Besnik Fetahu, Joachim Kimmerle
BACKGROUND: Consulting the Internet for health-related information is a common and widespread phenomenon, and Wikipedia is arguably one of the most important resources for health-related information. Therefore, it is relevant to identify factors that have an impact on the quality of health-related Wikipedia articles. OBJECTIVE: In our study we have hypothesized a positive effect of contributor experience on the quality of health-related Wikipedia articles. METHODS: We mined the edit history of all (as of February 2017) 18,805 articles that were listed in the categories on the portal health & fitness in the English language version of Wikipedia...
May 10, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29746963/patient-phenotypes-associated-with-outcome-following-surgery-for-mild-degenerative-cervical-myelopathy-a-principal-component-regression-analysis
#12
Jetan H Badhiwala, Christopher Witiw, Farshad Nassiri, Blessing Jaja, Muhammad A Akbar, Alireza Mansouri, Zamir Merali, George M Ibrahim, Jefferson R Wilson, Michael G Fehlings
BACKGROUND CONTEXT: Predictors of outcome after surgery for degenerative cervical myelopathy (DCM) have been determined previously through hypothesis-driven multivariate statistical models that rely on a priori knowledge of potential confounders, exclude potentially important variables due to restrictions in model building, cannot include highly collinear variables in the same model, and ignore intrinsic correlations among variables. PURPOSE: To apply a data-driven approach to identify patient phenotypes that may predict outcomes after surgery for mild DCM...
May 7, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29739634/mindfulness-based-exposure-and-response-prevention-for-obsessive-compulsive-disorder-findings-from-a-pilot-randomised-controlled-trial
#13
Clara Strauss, Laura Lea, Mark Hayward, Elizabeth Forrester, Tamara Leeuwerik, Anna-Marie Jones, Claire Rosten
BACKGROUND: Only about half of people with obsessive compulsive disorder (OCD) show clinically significant improvement following the recommended therapy, exposure and response prevention (ERP), partly due to poor therapy acceptability. A mindfulness-based approach to ERP (MB-ERP) has the potential to improve acceptability and outcomes. METHODS: This was an internal pilot randomised controlled trial (RCT) of group MB-ERP compared to group ERP. 37 participants meeting DSM-IV OCD criteria were randomly allocated to MB-ERP or ERP...
April 30, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29738299/perception-of-diabetic-foot-ulcers-among-general-practitioners-in-four-european-countries-knowledge-skills-and-urgency
#14
José Luis Garcia-Klepzig, Juan Pedro Sánchez-Ríos, Chris Manu, Raju Ahluwalia, Claas Lüdemann, Marco Meloni, Elisabetta Lacopi, Víctor Rodriguez-Saenz De Buruaga, Benjamin Bouillet, Julien Vouillarmet, Jose Luis Lazaro Martinez, Kristien Van Acker
OBJECTIVE: Diabetic foot ulcers (DFU) have the potential to deteriorate rapidly, in the absence of prompt assessment and treatment. The aim of this study was to analyse the awareness and perception of DFU among general practitioners (GPs) from four European countries, and to find possible differences between these countries in terms of management. METHOD: A two-part, quantitative, online questionnaire was distributed to GPs across four countries in Europe-the UK, France, Germany and Spain...
May 2, 2018: Journal of Wound Care
https://www.readbyqxmd.com/read/29736548/electric-field-mediated-elastic-contact-lithography-of-thin-viscoelastic-films-for-miniaturized-and-multiscale-patterns
#15
Abir Ghosh, Dipankar Bandyopadhyay, Ashutosh Sharma
Elastic contact lithography (ECL) and electric field lithography (EFL) have both shown significant potential to develop large-area micropatterns on polymeric surfaces. Recently, the major challenges associated with these processes have been the improvement of the aspect ratio and reduction in the size and periodicity of the patterns fabricated. Herein, with the help of non-linear simulations, we show that combining these methods can be one recipe to overcome these limitations. We consider a linear viscoelastic film for the linear and non-linear analyses...
May 8, 2018: Soft Matter
https://www.readbyqxmd.com/read/29735134/inter-and-intraobserver-reliability-of-pelvic-obliquity-measurement-methods-in-patients-with-cerebral-palsy
#16
M Wade Shrader, Emily M Andrisevic, Mohan V Belthur, Gregory R White, Carla Boan, William Wood
STUDY DESIGN: Retrospective, chart review. OBJECTIVES: The identification and management of pelvic obliquity in neuromuscular scoliosis can be difficult; therefore, appropriate evaluation of this pathology is important. Variations in presentation have resulted in various methods of measurement, without a consensus or gold standard measurement. This study is the evaluation of reliability of five methods commonly used to determine pelvic obliquity in the frontal plane...
May 2018: Spine Deformity
https://www.readbyqxmd.com/read/29733680/change-in-koos-and-womac-scores-in-a-young-athletic-population-with-and-without-anterior-cruciate-ligament-injury
#17
Ivan J Antosh, Steven J Svoboda, Karen Y Peck, E'Stephan J Garcia, Kenneth L Cameron
BACKGROUND: Several studies have examined changes in patient-reported outcome measures (PROMs) after anterior cruciate ligament (ACL) injury, but no studies to date have prospectively evaluated changes from preinjury baseline through injury and follow-up among ACL-injured patients compared to the baseline and follow-up changes of uninjured patients. PURPOSE: To examine changes in PROMs over time from preinjury baseline to at least 2 years after ACL reconstruction and to compare these changes with those of an uninjured control group having similar physical activity requirements...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29732712/dento-alveolar-measurements-and-histomorphometric-parameters-of-maxillary-and-mandibular-first-molars-using-micro-ct
#18
Charlotte E G Theye, André Hattingh, Tamsin J Cracknell, Anna C Oettlé, Maryna Steyn, Stefan Vandeweghe
BACKGROUND: Micro-CT is a high-resolution, non-invasive, and non-destructive imaging technique, currently acknowledged as a gold standard modality for assessing quantitatively and objectively dental morphology and bone microarchitecture parameters. PURPOSE: The aim of this study was to analyze critical dental and periodontal measurements characterizing the mandibular (MandFM) and maxillary (MaxFM) first molar architecture, as well as the corresponding bony socket, using micro-CT...
May 6, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29730138/establishing-maximal-medical-improvement-after-anatomic-total-shoulder-arthroplasty
#19
REVIEW
Richard N Puzzitiello, Avinesh Agarwalla, Joseph N Liu, Gregory L Cvetanovich, Anthony A Romeo, Brian Forsythe, Nikhil N Verma
BACKGROUND: As a heightened emphasis continues to be placed on value-based health care, quality outcomes following orthopedic procedures must be properly defined. With knowledge of the time to maximal medical improvement following total shoulder arthroplasty (TSA), physician resources can be justly allocated to optimize value in ambulatory orthopedic care. MATERIALS AND METHODS: A systematic review was conducted to identify studies reporting sequential follow-up at several time points, up to a minimum of 2 years after TSA...
May 2, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29729942/performance-of-the-asthma-impact-on-quality-of-life-scale-a-iqols-in-diverse-asthma-research-populations-and-demographic-sub-groups
#20
Sandra R Wilson, Robert A Wise, Mario Castro, Michael J Mulligan, Estela Ayala, Alan Chausow, Qiwen Huang, Santosh Gummidipundi
BACKGROUND: The Asthma Impact on Quality of Life Scale (A-IQOLS) assesses patient-perceived negative effect of asthma on quality of life (QoL). Its standard error of measurement is known, it has strong construct, convergent, and divergent validity, and provides information that is unique among asthma outcome measures. OBJECTIVE: To characterize A-IQOLS' psychometric properties and suitability for use in demographically and clinically diverse adult asthma populations...
May 3, 2018: Journal of Allergy and Clinical Immunology
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