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https://www.readbyqxmd.com/read/29913540/-significance-of-matrix-augmented-bone-marrow-stimulation-for-treatment-of-cartilage-defects-of-the-knee-a-consensus-statement-of-the-dgou-working-group-on-tissue-regeneration
#1
Philipp Niemeyer, Christoph Becher, Matthias Buhs, Stefan Fickert, Kolja Gelse, Daniel Günther, Raphael Kaelin, Peter Kreuz, Jörg Lützner, Stefan Nehrer, Henning Madry, Stefan Marlovits, Julian Mehl, Henning Ott, Matthias Pietschmann, Gunther Spahn, Thomas Tischer, Martin Volz, Markus Walther, Götz Welsch, Johannes Zellner, Wolfgang Zinser, Peter Angele
Surgical principles for treatment of full-thickness cartilage defects of the knee include bone marrow stimulation techniques (i.e. arthroscopic microfracturing) and transplantation techniques (i.e. autologous chondrocyte implantation and osteochondral transplantation). On the basis of increasing scientific evidence, indications for these established therapeutical concepts have been specified and clear recommendations for practical use have been given. Within recent years, matrix-augmented bone marrow stimulation has been established as a new treatment concept for chondral lesions...
June 18, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29913441/chondroprotective-effects-of-hyaluronic-acid-chitosan-nanoparticles-containing-plasmid-dna-encoding-cytokine-response-modifier-a-in-a-rat-knee-osteoarthritis-model
#2
Pang-Hu Zhou, Bo Qiu, Rong-Hui Deng, Hua-Jie Li, Xiong-Feng Xu, Xi-Fu Shang
BACKGROUND/AIMS: Interleukin (IL)-1β plays an essential role in the pathophysiology of osteoarthritis (OA). Cytokine response modifier A (CrmA) can prevent the generation of active IL-1β. This study aimed to explore the chondroprotective effects of hyaluronic acid-chitosan nanoparticles containing plasmid DNA encoding CrmA (HA/CS-CrmA) in a rat OA model. METHODS: HA/CS-CrmA nanoparticles were synthesized through the complex coacervation of cationic polymers. The characteristics, toxicity, and transfection of the nanoparticles were investigated...
June 15, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29913354/benefits-of-an-increased-prosthetic-ankle-range-of-motion-for-individuals-with-a-trans-tibial-amputation-walking-with-a-new-prosthetic-foot
#3
Daniel W W Heitzmann, Firooz Salami, Alan R De Asha, Julia Block, Cornelia Putz, Sebastian I Wolf, Merkur Alimusaj
BACKGROUND: Individuals with trans-tibial amputation show a greater peak prosthetic ankle power (push- off) when using energy storing and returning (ESAR) prosthetic feet as compared to solid-ankle cushion-heel feet. ESAR feet further contribute to the users' body support and thus limit prosthetic ankle motion. To improve ankle motion, articulating prosthetic feet have been introduced. However, articulating feet may diminish push-off. RESEARCH QUESTION: Does a novel prosthetic foot, with a serial layout of carbon fibre leaf springs, connected by a multi-centre joint construction, have advantages in kinematics and kinetics over a conventional ESAR prosthetic foot?> METHODS: Eleven individuals with unilateral trans-tibial amputation were fitted with the novel foot (NF) and a conventional ESAR Foot (CF) and underwent 3D gait analysis...
June 11, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29913027/patient-satisfaction-with-nonopioid-pain-management-following-knee-arthroscopic-partial-meniscectomy-and-or-chondroplasty
#4
Charles S Carrier, Kirsten D Garvey, Emily M Brook, Elizabeth G Matzkin
The purpose of this study was to determine the efficacy of nonopioid pain management following arthroscopic partial meniscectomy and/or chondroplasty and to assess patients' attitudes regarding their need for opioid pain medication following these procedures. Patients who underwent a knee arthroscopy procedure for either partial meniscectomy and/or chondroplasty from July 2016 to January 2017 by a single surgeon at a single institution were included. Medical records were reviewed, and demographics were recorded...
June 18, 2018: Orthopedics
https://www.readbyqxmd.com/read/29912981/correction-effects-of-collagen-matrix-and-bioreactor-cultivation-on-cartilage-regeneration-of-a-full-thickness-critical-size-knee-joint-cartilage-defects-with-subchondral-bone-damage-in-a-rabbit-model
#5
Kuo-Hwa Wang, Richard Wan, Li-Hsuan Chiu, Yu-Hui Tsai, Chia-Lang Fang, John F Bowley, Kuan-Chou Chen, Hsin-Nung Shih, Wen-Fu Thomas Lai
[This corrects the article DOI: 10.1371/journal.pone.0196779.].
2018: PloS One
https://www.readbyqxmd.com/read/29912857/stretch-could-reduce-hamstring-injury-risk-during-sprinting-by-right-shifting-the-length-torque-curve
#6
Mianfang Ruan, Li Li, Chen Chen, Xie Wu
Ruan, M, Li, L, Chen, C, and Wu, X. Stretch could reduce hamstring injury risk during sprinting by right shifting the length-torque curve. J Strength Cond Res XX(X): 000-000, 2018-It was hypothesized that static stretch would shift the length-torque curve to the right, which may reduce the risk of muscle strain injuries. The purpose of this study was to evaluate the acute effects of static stretching of hamstring (SSH) on the risk of hamstring injury during sprinting indicated by the shift of the length-torque relationship...
June 15, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29912806/corr-insights%C3%A2-intraocular-pressure-increases-after-intraarticular-knee-injection-with-triamcinolone-but-not-hyaluronic-acid
#7
Brian T Barlow
No abstract text is available yet for this article.
July 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29912747/editor-s-spotlight-take-5-increased-mortality-and-reoperation-rates-after-treatment-for-septic-arthritis-of-the-knee-in-people-who-inject-drugs-nationwide-inpatient-sample-2000-2013
#8
https://www.readbyqxmd.com/read/29912600/a-non-invasive-measurement-of-the-knee-contact-force-using-a-subject-specific-musculoskeletal-model-to-investigate-osteotomy
#9
Fateme Badie, Hamid Reza Katouzian, Mostafa Rostami
The varus knee has been defined as a Hip-Knee-Ankle alignment of less than 180 degrees. Varus knee alignment increases the load on the medial knee and also the risk of osteoarthritis. High tibial osteotomy has been designed to modify the malalignment of varus knee. The aim of this study was to investigate the osteotomy effects on knee adduction moment (KAM) and contact forces using a musculoskeletal and subject-specific knee model. A patient with varus knee and no symptoms of any other disease or disability participated in this study...
June 18, 2018: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/29912071/influence-of-sex-on-current-methods-of-adjusting-saddle-height-in-indoor-cycling
#10
Alberto Encarnación-Martínez, Ventura Ferrer-Roca, Juan García-López
Encarnación-Martínez, A, Ferrer-Roca, V, and García-López, J. Influence of sex on current methods of adjusting saddle height in indoor cycling. J Strength Cond Res XX(X): 000-000, 2018-The popularity of indoor cycling has increased in fitness centers, and therefore, proper bike fitting is important to avoid biomechanical-related injuries. However, no previous studies have compared the biomechanical kinematics of various existing protocols of saddle-height adjustment in indoor cycling. Furthermore, it was not clear if these protocols were appropriate for both men and women, as these equations were primarily obtained in male cyclists...
June 14, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29911741/intentional-weight-loss-for-overweight-and-obese-knee-osteoarthritis-patients-is-more-better
#11
Stephen P Messier, Allison E Resnik, Daniel P Beavers, Shannon L Mihalko, Gary D Miller, Barbara J Nicklas, Paul DeVita, David J Hunter, Mary F Lyles, Felix Eckstein, Ali Guermazi, Richard F Loeser
OBJECTIVE: To determine the dose response to weight loss on clinical and mechanistic outcomes in overweight and obese adults with knee osteoarthritis. METHODS: This is a secondary analysis of the diet-only (D) and diet plus exercise (D+E) groups in the Intensive Diet and Exercise for Arthritis (IDEA) randomized controlled clinical trial. Participants were 240 overweight and obese older community-dwelling adults with pain and radiographic knee OA. Participants were divided into 4 groups according to weight loss achieved over an 18-month period; less than 5% (<5% group), between 5 and 10% (≥5% group), between 10 and 20% (≥ 10% group), and greater than 20% (≥20% group)...
June 18, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29911739/ethnic-differences-in-preoperative-patient-characteristics-and-postoperative-functional-outcomes-after-total-knee-arthroplasty-among-chinese-malays-and-indians
#12
Nadir Zahir Shah, Rishi Malhotra, Choon Chiet Hong, Jonathan By Sng, Chee Hoe Kong, Liang Shen, Nazrul Nashi, Lingaraj Krishna
No abstract text is available yet for this article.
May 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29911616/pain-intensity-and-duration-in-a-cohort-of-norwegian-construction-workers
#13
K B Veiersted, L-K Lunde, M Koch, M Wærsted, S Knardahl
Aims To compare musculoskeletal pain intensity and duration of construction workers as a function of type of work. Methods 239 male construction workers in active employment filled out a (baseline) questionnaire for a prospective study of jobs with assumed heavy work load. Reports of pain presented here was collected from the men in four work categories; project leaders/foremen (N = 62, age 45 y, SD ± 13), carpenters (N = 60, 41 y ± 13), concrete workers (N = 35, 42 y ± 12) and miscellaneous other manual workers (e...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911584/knee-osteoarthritis-patients-with-intact-pain-modulating-systems-may-have-low-risk-of-persistent-pain-after-knee-joint-replacement
#14
Audun Stubhaug, Harald Breivik
No abstract text is available yet for this article.
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911577/the-dynamics-of-the-pain-system-is-intact-in-patients-with-knee-osteoarthritis-an-exploratory-experimental-study
#15
Tanja Schjødt Jørgensen, Marius Henriksen, Sara Rosager, Louise Klokker, Karen Ellegaard, Bente Danneskiold-Samsøe, Henning Bliddal, Thomas Graven-Nielsen
Background and aims Despite the high prevalence of knee osteoarthritis (OA) it remains one of the most frequent knee disorders without a cure. Pain and disability are prominent clinical features of knee OA. Knee OA pain is typically localized but can also be referred to the thigh or lower leg. Widespread hyperalgesia has been found in knee OA patients. In addition, patients with hyperalgesia in the OA knee joint show increased pain summation scores upon repetitive stimulation of the OA knee suggesting the involvement of facilitated central mechanisms in knee OA...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911491/performance-determinants-of-fixed-gear-cycling-during-criteriums
#16
Nicolas Babault, Maxime Poisson, Guiseppe Cimadoro, Carole Cometti, Christos Païzis
Nowadays, fixed gear competitions on outdoor circuits such as criteriums are regularly organized worldwide. To date, no study has investigated this alternative form of cycling. The purpose of the present study was to examine fixed gear performance indexes and to characterize physiological determinants of fixed gear cyclists. This study was carried out in two parts. Part 1 (n = 36) examined correlations between performance indexes obtained during a real fixed gear criterium (time trial, fastest laps, averaged lap time during races, fatigue indexes) and during a sprint track time trial...
June 17, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29911480/safety-and-feasibility-of-intravascular-lithotripsy-for-treatment-of-below-the-knee-arterial-stenoses
#17
Marianne Brodmann, Andrew Holden, Thomas Zeller
PURPOSE: To evaluate the safety and feasibility of treating calcified infrapopliteal stenoses using an intravascular lithotripsy (IVL) system. METHODS: The Disrupt BTK study was a prospective, nonrandomized, multicenter, feasibility, and safety trial that enrolled 20 patients (mean age 79.0±9.6 years; 14 men) at 3 participating sites ( ClinicalTrials.gov identifier NCT02911623). Fifteen patients had Rutherford category 5 ischemia, and all patients had moderate to severe below-the-knee arterial calcification...
June 1, 2018: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/29911282/knee-osteoarthritis-in-professional-football-is-related-to-severe-knee-injury-and-knee-surgery
#18
Vincent Gouttebarge, Haruhito Aoki, Gino M M J Kerkhoffs
BACKGROUND: As a consequence of severe knee injuries, knee osteoarthritis (OA) seems prevalent in retired professional footballers. However, some epidemiological data remain missing, for instance whether knee OA is also prevalent in current professional footballers, whether knee OA is associated with knee injuries and surgeries, and whether knee OA leads to a lower level of functioning. Therefore, three research questions were answered: (i) what is the prevalence of knee osteoarthritis (OA) among current and retired professional footballers? (ii) is severe knee injury or knee surgery associated with knee OA among current and retired professional footballers? (iii) what are the consequences of knee OA on physical knee function among current and retired professional footballers? METHODS: An observational study based on a cross-sectional design by means of questionnaires was conducted...
June 18, 2018: Injury Epidemiology
https://www.readbyqxmd.com/read/29911276/anti-inflammatory-drug-dexamethasone-treatment-during-the-remobilization-period-improves-range-of-motion-in-a-rat-knee-model-of-joint-contracture
#19
Akinori Kaneguchi, Junya Ozawa, Kaoru Yamaoka
Joint inflammation following remobilization is an important factor in the progression of arthrogenic contracture. We evaluated the effects of an anti-inflammatory treatment during the remobilization period of recovery after joint immobilization in rats. Three groups of rats had their right knee joints immobilized for 3 weeks using an external fixator at a flexion of 140° to generate flexion contracture. Next, the fixation device was removed, allowing immobilized knees to freely move again for 1 or 7 days...
June 18, 2018: Inflammation
https://www.readbyqxmd.com/read/29911143/simultaneous-quadruple-joint-replacement-qjr-in-disabling-juvenile-rheumatoid-arthritis-a-case-report-with-review-of-literature
#20
Rajesh Malhotra, Deepak Gautam, Bhavuk Garg, Anjan Trikha
We wish to present a case of 47-year-old patient with Juvenile Rheumatoid Arthritis and ankylosis of both hips and both knees treated by bilateral hip and knee arthroplasty in a single anaesthesia i.e. Quadruple joint replacement in single sitting. He was back on his feet from his bed-ridden state within the fortnight following surgery. He has been followed up for four years and has been performing his activities of daily living independently. We discuss the preoperative planning, surgical details and post-operative rehabilitation and unique challenges pertaining to this case...
May 2018: Archives of Bone and Joint Surgery
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