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https://www.readbyqxmd.com/read/28239936/the-cancer-care-experiences-of-gay-lesbian-and-bisexual-patients-a-secondary-analysis-of-data-from-the-uk-cancer-patient-experience-survey
#1
N J Hulbert-Williams, C O Plumpton, P Flowers, R McHugh, R D Neal, J Semlyen, L Storey
Understanding the effects of population diversity on cancer-related experiences is a priority in oncology care. Previous research demonstrates inequalities arising from variation in age, gender and ethnicity. Inequalities and sexual orientation remain underexplored. Here, we report, for the first time in the UK, a quantitative secondary analysis of the 2013 UK National Cancer Patient Experience Survey which contains 70 questions on specific aspects of care, and six on overall care experiences. 68,737 individuals responded, of whom 0...
February 27, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28239880/long-term-use-of-oral-nucleos-t-ide-analogues-for-chronic-hepatitis-b-does-not-increase-cancer-risk-a-cohort-study-of-44-494-subjects
#2
G L-H Wong, Y-K Tse, T C-F Yip, H L-Y Chan, K K-F Tsoi, V W-S Wong
BACKGROUND: Patients with chronic hepatitis B (CHB) need long-term antiviral treatment with nucleos(t)ide analogues (NA). Animal studies suggest that some NA may increase cancer risk, but human data are lacking. AIM: To investigate cancer risks in patients with or without NA treatment. METHODS: We conducted a territory-wide cohort study using the database from Hospital Authority in Hong Kong. The diagnosis of CHB and various malignancies was based on the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis codes between 2000 and 2012...
February 27, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28239699/stabilization-of-carbocations-ch3-c2h5-i-c3h7-tert-bu-and-cyclo-pentyl-in-solid-phases-experimental-data-versus-calculations
#3
Evgenii S Stoyanov, Anton S Nizovtsev
Comparison of experimental infrared (IR) spectra of the simplest carbocations (with the weakest carborane counterions in terms of basicity, CHB11Hal11(-), Hal = F, Cl) with their calculated IR spectra revealed that they are completely inconsistent, as previously reported for the t-Bu(+) cation [Stoyanov E. S., et al. J. Phys. Chem. A, 2015, 119, 8619]. This means that the generally accepted explanation of hyperconjugative stabilization of the carbocations should be revised. According to the theory, one CH bond (denoted as ) from each CH3/CH2 group transfers its σ-electron density to the empty 2pz orbital of the sp(2) C atom, whereas the σ-electron density on the other CH bonds of the CH3/CH2 group slightly increases...
February 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28239544/measures-of-metabolism-and-complexity-in-the-brain-of-patients-with-disorders-of-consciousness
#4
Olivier Bodart, Olivia Gosseries, Sarah Wannez, Aurore Thibaut, Jitka Annen, Melanie Boly, Mario Rosanova, Adenauer G Casali, Silvia Casarotto, Giulio Tononi, Marcello Massimini, Steven Laureys
BACKGROUND: Making an accurate diagnosis in patients with disorders of consciousness remains challenging. (18)F-fluorodeoxyglucose (FDG)-PET has been validated as a diagnostic tool in this population, and allows identifying unresponsive patients with a capacity for consciousness. In parallel, the perturbational complexity index (PCI), a new measure based on the analysis of the electroencephalographic response to transcranial magnetic stimulation, has also been suggested as a tool to distinguish between unconscious and conscious states...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28239516/nonmotor-symptoms-in-primary-adult-onset-cervical-dystonia-and-blepharospasm
#5
Jing Yang, Na Shao, Wei Song, Qianqian Wei, Ruwei Ou, Ying Wu, Hui-Fang Shang
BACKGROUND: The nature and frequency of nonmotor symptoms in primary adult-onset cervical dystonia (CD) and blepharospasm (BSP) patients in Chinese populations remain unknown. METHODS: Hamilton's Depression Scale (HAMD), Hamilton's Anxiety Scale (HAMA), Addenbrooke's Cognitive Examination Revised (ACE-R), Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale were used to evaluate NMS in 120 patients with primary focal adult-onset dystonia (60 with BSP and 60 with CD) and 60 age-, sex-, and education level- matched healthy controls (HCs)...
February 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28239499/a-dual-case-of-peritonitis-and-central-nervous-system-infection-caused-by-nutritionally-variant-streptococcal-species
#6
Sussi Vivar, Jennifer E Girotto, Thomas S Murray
Nutritional variant streptococci (NVS) are difficult to identify bacteria that can cause invasive infections such as endocarditis and meningitis. NVS as a cause of peritonitis has not been routinely described. This case of NVS as the etiology of peritonitis associated with previous neurosurgery and ventriculoperitoneal (VP) shunt revision demonstrates its potential role as a significant pathogen in patients with peritonitis and VP shunts. Therapy consists of vancomycin plus a second agent but since there are no standards for susceptibility testing, clinical response remains the standard for determining the efficacy of treatment...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28239485/protocol-for-the-evaluation-of-a-digital-storytelling-approach-to-address-stigma-and-improve-readiness-to-seek-services-among-veterans
#7
Brian E Bunnell, Tatiana M Davidson, Jessica L Hamblen, Danna L Cook, Anouk L Grubaugh, Brian E Lozano, Peter W Tuerk, Kenneth J Ruggiero
BACKGROUND: Research suggests that at least 10% of veterans returning from Iraq and Afghanistan meet criteria for posttraumatic stress disorder (PTSD) related to their military experiences. National dissemination initiatives have increased veterans' access to best-practice interventions. However, treatment-seeking remains low among veterans with PTSD, often due to perceived stigma and other associated barriers. The National Center for PTSD recently developed and launched AboutFace, a digital storytelling (DST) resource designed to help veterans recognize PTSD and motivate them to seek evidence-based treatment...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28239386/local-climate-heterogeneity-shapes-population-genetic-structure-of-two-undifferentiated-insular-scutellaria-species
#8
Huan-Yi Hsiung, Bing-Hong Huang, Jui-Tse Chang, Yao-Moan Huang, Chih-Wei Huang, Pei-Chun Liao
Spatial climate heterogeneity may not only affect adaptive gene frequencies but could also indirectly shape the genetic structure of neutral loci by impacting demographic dynamics. In this study, the effect of local climate on population genetic variation was tested in two phylogenetically close Scutellaria species in Taiwan. Scutellaria taipeiensis, which was originally assumed to be an endemic species of Taiwan Island, is shown to be part of the widespread species S. barbata based on the overlapping ranges of genetic variation and climatic niches as well as their morphological similarity...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28239314/second-korean-guidelines-for-the-management-of-crohn-s-disease
#9
REVIEW
Jae Jun Park, Suk-Kyun Yang, Byong Duk Ye, Jong Wook Kim, Dong Il Park, Hyuk Yoon, Jong Pil Im, Kang Moon Lee, Sang Nam Yoon, Heeyoung Lee
Crohn's disease (CD) is a chronic, progressive, and disabling inflammatory bowel disease (IBD) with an uncertain etiopathogenesis. CD can involve any site of the gastrointestinal tract from the mouth to the anus, and is associated with serious complications, such as bowel strictures, perforations, and fistula formation. The incidence and prevalence rates of CD in Korea are still lower compared with those in Western countries, but they have been rapidly increasing during the recent decades. Although there are no definitive curative modalities for CD, various medical and surgical therapies have been applied for the treatment of this disease...
January 2017: Intestinal Research
https://www.readbyqxmd.com/read/28238990/factorial-invariance-and-convergent-validity-of-the-group-based-medical-mistrust-scale-across-gender-and-ethnoracial-identity
#10
Christopher W Wheldon, Stephanie K Kolar, Natalie D Hernandez, Ellen M Daley
The objective of this study was to assess the factorial invariance and convergent validity of the Group-Based Medical Mistrust Scale (GBMMS) across gender (male and female) and ethnoracial identity (Latino and Black). Minority students (N = 686) attending a southeastern university were surveyed in the fall of 2011. Psychometric analysis of the GBMMS was performed. A three-factor solution fit the data after the omission of two problematic items. This revised version of the GBMMS exhibited sufficient configural, metric, and scalar invariance...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28238986/symptomology-of-elevated-blood-pressure-in-black-women-with-hypertension
#11
Devita T Stallings, Joanne Kraenzle Schneider
Understanding factors that influence hypertension self-management may improve blood pressure control in Black women; however, little is known about Black women's perceptions of symptoms associated with hypertension. In this study, using the revised version of the Illness Perception Questionnaire (IPQ-R), we examined Black women's perceptions of symptoms that they associate with hypertension. While over half (52.5%) reported no symptoms of high blood pressure, 41.3% of the women reported one to six symptoms they attributed to high blood pressure...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28238584/perioperative-and-early-postoperative-comparison-of-a-modern-cemented-and-cementless-total-knee-arthroplasty-of-the-same-design
#12
Denis Nam, Judith E Kopinski, Zachary Meyer, Richard D Rames, Ryan M Nunley, Robert L Barrack
BACKGROUND: Cementless total knee arthroplasty (TKA) designs that incorporate a highly porous, titanium surface have the potential to achieve biologic fixation and improve component survivorship. This study's purpose was to compare perioperative and early postoperative outcomes of a cemented vs cementless TKA of the same design. METHODS: This was a retrospective review of a consecutive series of TKAs performed at a single institution using a cemented or cementless TKA of the same design (Triathlon, Stryker Inc, Mahwah, NJ)...
February 7, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28238582/do-high-flexion-total-knee-designs-increase-the-risk-of-femoral-component-loosening
#13
Young-Hoo Kim, Jang-Won Park, Jun-Shik Kim
BACKGROUND: The purpose of our prospective, randomized, long-term investigation is to compare the aseptic loosening rate of the femoral component of the total knee prosthesis and clinical and radiographic results of high-flexion posterior cruciate-substituting knee prosthesis or standard posterior cruciate-substituting knee prosthesis in the same patients. METHODS: There were 960 patients (mean age 71.3 years). The mean follow-up period was 13.2 years (range 10-14)...
February 4, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28238580/concurrent-central-venous-stent-and-central-venous-access-device-placement-does-not-compromise-stent-patency-or-catheter-function-in-patients-with-malignant-central-venous-obstruction
#14
Katherine Clark, Jeffrey Forris Beecham Chick, Shilpa N Reddy, Benjamin J Shin, Gregory J Nadolski, Timothy W Clark, Scott O Trerotola
PURPOSE: To determine if concurrent placement of a central venous stent (CVS) and central venous access device (CVAD) compromises stent patency or catheter function in patients with malignant central venous obstruction. MATERIALS AND METHODS: CVS placement for symptomatic stenosis resulting from malignant compression was performed in 33 consecutive patients who were identified retrospectively over a 10-year period; 28 (85%) patients had superior vena cava syndrome, and 5 (15%) had arm swelling...
February 23, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28238496/prevalence-of-polycystic-ovary-syndrome-in-chinese-obese-women-of-reproductive-age-with-or-without-metabolic-syndrome
#15
Peiwen Liang, Liuqing Xi, Juan Shi, Wanyu Li, Shaoqian Zhao, Yuying Deng, Rui Wang, Yingkai Sun, Bin Gu, Lihui Yuan, Yifei Zhang, Weiqiong Gu, Weiqing Wang, Jie Hong
OBJECTIVE: To compare the prevalence of polycystic ovary syndrome (PCOS) and related clinical characteristics between metabolically unhealthy obese (MUO) and metabolically healthy obese (MHO) women of reproductive age. DESIGN: Cross-sectional clinical study. SETTING: Tertiary hospital. PATIENT(S): We studied 299 MUO and 122 MHO Chinese women matched on body mass index. Metabolically healthy obese was defined as obesity with no more than one metabolic abnormality...
February 23, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28238388/multicenter-evaluation-of-the-revised-rida%C3%A2-quick-test-n1402-for-rapid-detection-of-norovirus-in-a-diagnostic-laboratory-setting
#16
Stijn Jonckheere, Nadine Botteldoorn, Patricia Vandecandelaere, Johan Frans, Wim Laffut, Guy Coppens, Anne Vankeerberghen, Hans De Beenhouwer
The updated RIDA® QUICK (N1402) immunochromatographic assay (R-Biopharm) for detection of norovirus was evaluated during a prospective, multicenter study using 771 stool samples from patients with gastroenteritis. Compared to real-time reverse transcriptase polymerase chain reaction (RT-rtPCR) as gold standard, the RIDA® QUICK had an overall sensitivity of 72.8% (91/125) and a specificity of 99.5% (640/643). Genotype analysis of the polymerase (ORF1) and capsid (ORF2) region of the genome indicated that the RIDA® QUICK assay could detect a broad range of genotypes including new variants (15 of 125 positive samples) which were detected by an in-house SYBR®Green RT-rtPCR, but not by the RIDA® GENE PCR PG1415 (R-Biopharm) and mostly not by the RIDA® GENE PCR PG1405 and the Xpert® Norovirus assay (Cepheid)...
February 12, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28238178/verification-of-recall-criteria-for-masses-detected-on-ultrasound-breast-cancer-screening
#17
Kanako Ban, Hiroko Tsunoda, Sakiko Suzuki, Rie Takaki, Kyouko Sasaki, Minako Nakagawa
PURPOSE: Mammography is the only modality for breast cancer screening demonstrated to reduce the mortality rate. However, ultrasonographic screening is already being widely performed as opportunistic screening in Japan. The recall criteria for masses are very important as quality controls. The purpose of this study was to verify these criteria at multiple institutions. METHODS: Screening was performed by five institutions in various regions in Japan. The total number of cases screened at all five institutions was 10,519...
February 25, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28238115/sex-differences-in-diagnosis-and-clinical-phenotypes-of-chinese-children-with-autism-spectrum-disorder
#18
Shihuan Wang, Hongzhu Deng, Cong You, Kaiyun Chen, Jianying Li, Chun Tang, Chaoqun Ceng, Yuanyuan Zou, Xiaobing Zou
The aim of this study was to explore the differences between boys and girls in the diagnosis and clinical phenotypes of autism spectrum disorder (ASD) in China's mainland. Children diagnosed with ASD (n = 1064, 228 females) were retrospectively included in the analysis. All children were assessed using the Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS). The results showed that girls scored significantly higher in ADI-R socio-emotional reciprocity than boys, and also scored lower in ADI-R and ADOS restricted and repetitive behaviors (RRBs)...
February 25, 2017: Neuroscience Bulletin
https://www.readbyqxmd.com/read/28238012/two-revision-surgeries-on-cemented-custom-made-tumor-prostheses
#19
Yukihiro Yoshida, Yuki Okamura, Mamoru Akita, Masashi Taniguchi, Toshio Kojima, Eiji Osaka, Yasuaki Tokuhashi
We performed revision surgery in 2 patients for stem fracture of a cemented tumor prosthesis that occurred more than 25 years after the initial surgery. For revision, the global modular replacement system (GMRS) was used. However, as bone cement in the bone could not be adequately removed, stems with respective diameters of 11 and 12.5 mm were used. In revision surgery for cemented tumor prostheses, adequate removal of residual bone cement is optimal. However, when there is a risk of fracture, it may be appropriate to insert a thicker stem after reaming the femoral canal as much as possible, and then fix the stem using the cement-in-cement method...
February 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28238009/results-of-total-elbow-arthroplasty-with-cementless-implantation-of-an-alumina-ceramic-elbow-prosthesis-for-patients-with-rheumatoid-arthritis
#20
Keiichiro Nishida, Kenzo Hashizume, Masatsugu Ozawa, Ayumu Takeshita, Daisuke Kaneda, Ryuichi Nakahara, Yoshihisa Nasu, Yasunori Shimamura, Hajime Inoue, Toshifumi Ozaki
We investigated the long-term clinical results of total elbow arthroplasty (TEA) by cementless fixation of alumina ceramic unlinked elbow prostheses (J-alumina ceramic elbows: JACE) for the reconstruction of elbow joints with rheumatoid arthritis (RA). Seventeen elbows in 17 patients (aged 44-72 years, average 54.8) replaced by JACE TEA without bone cement were investigated. The average follow-up period was 10.7 (range, 1.0-19.3) years. Clinical conditions of each elbow before and after surgery were assessed according to the Mayo Elbow Performance Index (MEPI)...
February 2017: Acta Medica Okayama
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