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https://www.readbyqxmd.com/read/29223777/child-care-centre-adherence-to-infant-physical-activity-and-screen-time-recommendations-in-australia-canada-and-the-united-states-an-observational-study
#1
Lyndel Hewitt, Sara E Benjamin-Neelon, Valerie Carson, Rebecca M Stanley, Ian Janssen, Anthony D Okely
OBJECTIVE: The aim of this study was to compare adherence to physical activity and sedentary behaviour recommendations within the 2011 Institute of Medicine Early Childhood Obesity Prevention Policies as well as screen time recommendations from the 2013 American Academy of Pediatrics for samples of infants in child care centres in Australia, Canada, and the United States (US). METHODS: This cross-sectional study used data from: the Australian 2013 Standing Preschools (N=9) and the 2014-2017 Early Start Baseline (N=22) studies; the 2011 Canadian Healthy Living Habits in Pre-School Children study (N=14); and the American 2008 (N=31) and 2013-2017 (N=31) Baby Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) trials...
December 7, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/29223391/effects-of-a-hydroethanolic-extract-of-boophone-disticha-bulb-on-anxiety-related-behaviour-in-naive-balb-c-mice
#2
William Pote, Shamiso Musarira, Donald Chuma, Louis L Gadaga, Ellen Mwandiringana, Dexter Tagwireyi
ETHNOPHARMACOLOGICAL RELEVANCE: Boophone disticha is one of the most important medicinal bulbs of Southern Africa. Previous in vitro studies have shown that it's crude ethanolic extracts and some alkaloidal phytoconstituents possesses high affinity for the serotonin transporter protein (SERT) and serotonin receptor 1a (5HT1a) which are both implicated in the pathogenesis and treatment of anxiety disorders. However, there are no in vivo studies that validates the anxiolytic actions of the plant...
December 6, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29222619/improvement-in-obstructive-sleep-apnea-after-a-tailored-behavioural-sleep%C3%A2-medicine-intervention-targeting-healthy-eating-and-physical-activity-a-randomised-controlled-trial
#3
Helena Igelström, Pernilla Åsenlöf, Margareta Emtner, Eva Lindberg
PURPOSE: The aim of the present single-centre randomised controlled trial was to assess the effect of a behavioural sleep medicine (BSM) intervention on obstructive sleep apnea (OSA) severity in patients who have been referred for new treatment with continuous positive airway pressure (CPAP). METHODS: After baseline assessment including ventilatory and anthropometric parameters, and physical activity monitoring, 86 patients who were overweight (BMI ≥ 25) and had moderate-severe OSA with apnea-hypopnea index (AHI) ≥ 15 were randomised into a control group (CG; CPAP and advice about weight loss) or an experimental group (ExpG; CPAP and BSM intervention targeting physical activity and eating behaviour)...
December 8, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29219669/metabolic-profile-elucidation-of-zhi-zi-da-huang-decoction-in-rat-intestinal-bacteria-using-high-resolution-mass-spectrometry-combined-with-multiple-analytical-perspectives
#4
Miao Wang, Qing Hu, Qingshui Shi, Gongjun Yang, Fang Feng
1. Zhi-Zi-Da-Huang decoction (ZZDHD) has been widely used for the treatment of alcoholic jaundice, alcoholic liver disease and acute hepatitis in China for thousands of years. Conventionally decoctions are administered orally, after which the metabolism caused by the enzymes in intestinal bacteria may influence significantly on the curative effects or toxicity. 2. In this work, the comprehensive metabolic process of ZZDHD in intestinal bacteria was investigated reliably using high resolution HPLC-DAD-ESI-TOF/MS...
December 8, 2017: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
https://www.readbyqxmd.com/read/29219248/-my-mother-told-me-that-i-should-not-a-qualitative-study-exploring-the-restrictions-placed-on-adolescent-girls-living-with-hiv-in-zambia
#5
Constance Rs Mackworth-Young, Virginia Bond, Alison Wringe, Katongo Konayuma, Sue Clay, Chipo Chiiya, Mutale Chonta, Kirsty Sievwright, Anne L Stangl
INTRODUCTION: Adolescent girls in sub-Saharan Africa are disproportionately affected by HIV due to a range of social and structural factors. As they transition to adulthood, they are recipients of increasing blame for HIV infection and 'improper' sex, as well as increasing scrutiny, restrictions and surveillance. This study used a qualitative and participatory approach to explore the messaging and restrictions imposed on adolescent girls living with HIV in Zambia. METHODS: Thirty-four in-depth interviews and four participatory workshops were carried out with 24 adolescent girls aged 15 to 19 years old living with HIV in Lusaka, Zambia...
December 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29214157/towards-a-global-initiative-for-fibrosis-treatment-gift
#6
Maria Molina-Molina, Alvar Agusti, Bruno Crestani, David A Schwartz, Melanie Königshoff, Rachel C Chambers, Toby M Maher, Rosa Faner, Ana Lucia Mora, Mauricio Rojas, Katerina M Antoniou, Jacobo Sellares
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterised by increased scarring of lung tissue. Despite the recent introduction of novel drugs that slow disease progression, IPF remains a deadly disease, and the benefits of these new drugs differ markedly between patients. Human diseases arise due to alterations in an almost limitless network of interconnected genes, proteins, metabolites, cells and tissues, in direct relationship with a continuously changing macro- or microenvironment...
October 2017: ERJ Open Research
https://www.readbyqxmd.com/read/29212546/electronic-laboratory-medicine-ordering-with-evidence-based-order-sets-in-primary-care-elmo-study-protocol-for-a-cluster-randomised-trial
#7
Nicolas Delvaux, An De Sutter, Stijn Van de Velde, Dirk Ramaekers, Steffen Fieuws, Bert Aertgeerts
BACKGROUND: Laboratory testing is an important clinical act with a valuable role in screening, diagnosis, management and monitoring of diseases or therapies. However, inappropriate laboratory test ordering is frequent, burdening health care spending and negatively influencing quality of care. Inappropriate tests may also result in false-positive results and potentially cause excessive downstream activities. Clinical decision support systems (CDSSs) have shown promising results to influence the test-ordering behaviour of physicians and to improve appropriateness...
December 6, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29211054/barriers-and-facilitators-for-information-exchange-during-over-the-counter-consultations-in-community-pharmacy-a-focus-group-study
#8
Liza J Seubert, Kerry Whitelaw, Fabienne Boeni, Laetitia Hattingh, Margaret C Watson, Rhonda M Clifford
Consumers are confident managing minor ailments through self-care, often self-medicating from a range of over-the-counter (OTC) medicines available from community pharmacies. To minimise risks, pharmacy personnel endeavour to engage in a consultation when consumers present with OTC enquiries however they find consumers resistant. The aim was to determine stakeholder perspectives regarding barriers and facilitators for information exchange during OTC consultations in community pharmacies and to understand the elicited themes in behavioural terms...
December 6, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29207730/safety-assessment-of-human-bone-marrow-derived-mesenchymal-stromal-cells-transplantation-in-wistar-rats
#9
Ashwini P Aithal, Laxminarayana Kurady Bairy, Raviraja N Seetharam
Introduction: Bone Marrow-derived Mesenchymal Stromal Cells (BM-MSCs) are multipotent stem cells isolated from adult human bone marrow. Properties of MSCs make them potentially ideal candidates for regenerative medicine. The preclinical data available in the literature regarding the safety assessment of MSCs at different dosage group is scanty. Aim: To evaluate the safety of BM-MSCs transplantation in Wistar rats. Materials and Methods: Eighteen adult female Wistar rats were used in the study...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29207713/analysis-of-patient-s-satisfaction-with-phlebotomy-services-in-nabh-accredited-neuropsychiatric-hospital-an-effective-tool-for-improvement
#10
Anshu Gupta, Tanima Dwivedi, Sadhana, Raju Chaudhary
Introduction: Patient's satisfaction is the need of the hour and one of the most important quality indicators in the laboratory medicine. Aim: To assess the patient's satisfaction with phlebotomy services in a neuropsychiatric hospital by a structured questionnaire with grading scale. Also, identify the problems causing dissatisfactions and to undertake necessary Corrective and Preventative Action (CAPA). Materials and Methods: Total 1200 patients were randomly selected over a period of two months (June and July 2016)...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29205419/community-pharmacists-leaders-for-antibiotic-stewardship-in-respiratory-tract-infection
#11
S Essack, J Bell, A Shephard
WHAT IS KNOWN AND OBJECTIVE: Hospital-based pharmacists are established antibiotic stewards, but the potential for community pharmacists is largely untapped. This commentary explores the potential leadership role of the community pharmacist in antibiotic stewardship using upper respiratory tract infection (URTI) as an example. COMMENT: Community pharmacists are well placed for antibiotic stewardship, possessing the capability (knowledge of medicines), opportunity (contact with prescribers and patients) and inherent commitment...
December 4, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29202423/suicide-and-self-harm-in-nepal-a-scoping-review
#12
REVIEW
Suresh Thapaliya, Pawan Sharma, Kapil Upadhyaya
BACKGROUND: Suicide and self harm behavior has become a major public health issue in recent years in Nepal. This small south Asian country was ranked 7th by suicide rate globally by the 2014 World Health Organization report with an estimated 6,840 suicides annually, or 24.9 suicides per 100,000 people. We decided to explore the epidemiology of suicidal behaviour and self harm, modes of attempt, associated risk factors and trends in specific population. METHODOLOGY: Two researchers independently reviewed 47 studies published in the US National Library of Medicine's PubMed electronic Database and Google Scholar till December 2016...
December 1, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29194912/sharing-of-prescription-analgesics-amongst-patients-in-family-practice-frequency-and-associated-factors
#13
F Markotic, D Jurisic, M Curkovic, M Puljiz, M Novinscak, K Bonassin, D Vrdoljak, Z Vojvodic, S Permozer Hajdarovic, T Pekez-Pavlisko, M Tomicic, I Diminic-Lisica, S Fabris Ivsic, D Nejasmic, I Miosic, I Novak, L Puljak
OBJECTIVE: To analyse the frequency of nonrecreational prescription analgesic sharing, associated factors and differences between lenders and borrowers. METHODS: A cross-sectional study was conducted in 10 outpatient family medicine practices in Croatia amongst 1000 patients to whom their physicians have prescribed analgesics at least once in their lives. A questionnaire was used to collect data about patients' pain intensity, prescription analgesic sharing habits, factors associated with this behaviour, perception of risks associated with the conduct and demographic data...
December 1, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29193284/drug-burden-index-to-define-the-burden-of-medicines-in-older-adults-with-intellectual-disabilities-an-observational-cross-sectional-study
#14
J O'Connell, E Burke, N Mulryan, C O'Dwyer, C Donegan, P McCallion, M McCarron, M C Henman, M O'Dwyer
AIMS: The Drug Burden Index (DBI) is a dose-related measure of anticholinergic and sedative drug exposure. This cross-sectional study described DBI in older adults with intellectual disabilities (ID) and the most frequently reported therapeutic classes contributing to DBI and examined associations between higher DBI scores and potential adverse effects as well as physical function. METHODS: This study analysed data from Wave 2 (2013/2014) of the Intellectual Disability Supplement to the Irish Longitudinal Study on Ageing (IDS-TILDA), a representative study on the ageing of people with ID in Ireland...
November 29, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29188883/dietary-approach-to-stop-hypertension-with-sodium-reduction-for-chinese-canadians-dashna-cc-a-pilot-randomized-controlled-trial
#15
P Zou, C-L Dennis, R Lee, M Parry
BACKGROUND: There is a lack of culturally sensitive dietary interventions targeting Chinese Canadians despite unhealthy dietary behaviours being identified as the most important modifiable risk factor for hypertension in the Chinese population. AIMS: To determine the feasibility of a culturally sensitive dietary intervention for hypertension control; to examine the potential effects of the intervention on blood pressure and health-related quality of life among Chinese Canadians in community...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29186647/-students-clinical-nurse-preceptors-and-academic-tutors-perception-and-experience-in-relation-to-the-implementation-of-a-dedicated-education-unit-a-qualitative-study-using-focus-group
#16
Loris Bonetti, Manuela Cattalani, Angela Pacciani, Cristina Angelini, Patrizia Basile, Maria Cristina Currà, Ernesto Evicelli, Daniela Spotti, Carmela Crisalide, Giuseppina LeDonne
OBJECTIVE: analyse students, clinical nurse preceptors and academic tutors' perception and experience further to the implementation of a Dedicated Education Unit (DEU) in a pulmonary medicine ward. METHOD: The study follows a qualitative descriptive method. Data have been collected through focus groups (FGs). We have organized four different FGs, a specific focus group for each stakeholder (students, nurses and tutors) and a closing one with everybody. Each FG followed a qualitative content analysis method...
July 2017: Professioni Infermieristiche
https://www.readbyqxmd.com/read/29185627/strategies-for-enhancing-the-implementation-of-school-based-policies-or-practices-targeting-risk-factors-for-chronic-disease
#17
REVIEW
Luke Wolfenden, Nicole K Nathan, Rachel Sutherland, Sze Lin Yoong, Rebecca K Hodder, Rebecca J Wyse, Tessa Delaney, Alice Grady, Alison Fielding, Flora Tzelepis, Tara Clinton-McHarg, Benjamin Parmenter, Peter Butler, John Wiggers, Adrian Bauman, Andrew Milat, Debbie Booth, Christopher M Williams
BACKGROUND: A number of school-based policies or practices have been found to be effective in improving child diet and physical activity, and preventing excessive weight gain, tobacco or harmful alcohol use. Schools, however, frequently fail to implement such evidence-based interventions. OBJECTIVES: The primary aims of the review are to examine the effectiveness of strategies aiming to improve the implementation of school-based policies, programs or practices to address child diet, physical activity, obesity, tobacco or alcohol use...
November 29, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29182956/unintentional-mortality-associated-with-paracetamol-and-codeine-preparations-with-and-without-doxylamine-in-australia
#18
Ria E Hopkins, Malcolm Dobbin, Jennifer L Pilgrim
INTRODUCTION: Misuse of paracetamol, codeine and doxylamine combination analgesics may lead to addiction and mortality. This study aimed to (1) identify unintentional deaths in Australia associated with use of combination analgesic products containing paracetamol, codeine and doxylamine; (2) describe cases characteristics, including demographics and additional medication use; and (3) identify common factors associated with misuse and mortality of these medicines in Australia. DESIGN: This retrospective case series analysed National Coronial Information System data to identify cases of unintentional death attributable to paracetamol, codeine and doxylamine products between 2002 and 2012...
November 23, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29175885/how-effective-is-community-physical-activity-promotion-in-areas-of-deprivation-for-inactive-adults-with-cardiovascular-disease-risk-and-or-mental-health-concerns-study-protocol-for-a-pragmatic-observational-evaluation-of-the-active-herts-physical-activity-programme
#19
Neil Howlett, Andy Jones, Lucy Bain, Angel Chater
INTRODUCTION: There is a high prevalence of inactive adults in the UK, and many suffer from conditions such as cardiovascular disease (CVD) or poor mental health. These coexist more frequently in areas of higher socioeconomic deprivation. There is a need to test the effectiveness, acceptability and sustainability of physical activity programmes. Active Herts uses novel evidence-based behaviour change techniques to target physical inactivity. METHODS AND ANALYSIS: Active Herts is a community physical activity programme for inactive adults aged 16+ with one or more risk factors for CVD and/or a mild to moderate mental health condition...
November 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/29171414/non-invasive-electrical-brain-stimulation-from-acute-to-late-stage-treatment-of-central-nervous-system-damage
#20
REVIEW
Petra Henrich-Noack, Elena G Sergeeva, Bernhard A Sabel
Non-invasive brain current stimulation (NIBS) is a promising and versatile tool for inducing neuroplasticity, protection and functional rehabilitation of damaged neuronal systems. It is technically simple, requires no surgery, and has significant beneficial effects. However, there are various technical approaches for NIBS which influence neuronal networks in significantly different ways. Transcranial direct current stimulation (tDCS), alternating current stimulation (ACS) and repetitive transcranial magnetic stimulation (rTMS) all have been applied to modulate brain activity in animal experiments under normal and pathological conditions...
October 2017: Neural Regeneration Research
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