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https://www.readbyqxmd.com/read/28433961/harnessing-the-medical-humanities-for-experiential-learning
#1
Satendra Singh, Purnima Barua, Upreet Dhaliwal, Navjeevan Singh
A month-long workshop on medical humanities was held in the Jorhat Medical College, Assam in September 2015. It employed experiential learning (both online and onsite) using humanities tools, such as the theatre of the oppressed, art, literature, reflective narratives, movies, the history of medicine, graphic medicine, poetry and diversity studies. As a result of the interactions, 28 volunteer participants, comprising students and faculty members, wrote reflective narratives on doctor​-patient relationships, produced a newsletter and a logo for their medical humanities group, and staged cultural performances and forum theatre...
March 29, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28432185/exogenous-cushing-s-syndrome-due-to-a-chinese-herbalist-s-prescription-of-ointment-containing-dexamethasone
#2
Viola Franke, Winnie Francien Scholtens, Ines Alexandra von Rosenstiel, Marie Jose Walenkamp
Eczema in children is a chronic disabling condition. The impact of this condition on the lives of families is often underestimated by conventional physicians. As a consequence parents may investigate complementary treatment options. Close monitoring by a paediatrician is essential, considering that a variety of adverse effects can occur during the use of complementary treatment. We present a 5-year-old girl with eczema. She visited a Chinese herbalist who prescribed an ointment. The parents noticed that the eczema resolved fast, itching decreased and she was finally sleeping well...
April 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28429997/attitudes-toward-cognitive-enhancer-use-among-new-zealand-tertiary-students
#3
Sanyogita Sanya Ram, Safeera Hussainy, Marcus Henning, Kay Stewart, Maree Jensen, Bruce Russell
BACKGROUND: Cognitive enhancement is the use of prescription stimulant medicines by healthy individuals for nonmedical use in academic settings. Commonly used cognitive enhancers (CEs) include methylphenidate, amphetamines, and modafinil. To understand the motivation to use CEs, it is important to look beyond prevalence and explore the extent to which attitudes, beliefs, and intentions predict the decision to use CEs. OBJECTIVE: The study aimed to investigate what factors explain the decision to use CEs among tertiary students in New Zealand, using the Theory of Planned Behaviour (TPB)...
April 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28427041/the-efficacy-of-donepezil-administration-on-acetylcholinesterase-activity-and-altered-redox-homeostasis-in-alzheimer-s-disease
#4
Pinar Atukeren, Mahir Cengiz, Hakan Yavuzer, Remise Gelisgen, Esma Altunoglu, Sena Oner, Fusun Erdenen, Damla Yuceakın, Himmet Derici, Ufuk Cakatay, Hafize Uzun
Alzheimer's disease (AD) is a serious multifactorial disorder with progressive neurodegenerative outcomes related with impaired redox homeostasis. Inhibition of the enzyme acetylcholinesterase (AChE), as one of the major therapeutic strategies, is considered to be offering only symptomatic relief and moderate disease modifying effect. We intended to investigate the effects of acetylcholinesterase inhibition via donepezil on protein carbonyl (PCO), advanced protein oxidation products (AOPP) and ischemia modified albumin (IMA) as protein oxidation markers and ferric reducing antioxidant power (FRAP), prooxidant-antioxidant balance (PAB), total thiol (T-SH), protein thiol (P-SH) as antioxidant status markers and also kynurenine (KYN), N-formyl kynurenine (N-FKYN) and protein bound dityrosine (DT) levels all in one demonstrating the redox homeostasis in Alzheimer patients also correlated with AChE activity...
April 17, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28426117/identifying-the-gaps-in-nepalese-migrant-workers-health-and-well-being-a-review-of-the-literature
#5
Padam P Simkhada, Pramod R Regmi, Edwin van Teijlingen, Nirmal Aryal
Background: The health and well-being of migrant workers from low-income countries is often neglected in travel medicine. This article uses Nepal as a case study to highlight key issues affecting this particular group of international travellers. Methods: This narrative review used a comprehensive systematic literature search to identify relevant studies on Nepal. The included articles were thematically analysed leading to four key themes or risk factors. Results: The search found 18 articles from which we identified 3 key themes related directly to migrant workers: (1) sexual risk taking; (2) occupational health and (3) lifestyles, and a fourth theme related to partners and family of migrant workers who are left behind in Nepal...
July 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28425891/teaching-psychology-in-medicine-the-context-methodologies-and-doctor-s-professional-identity
#6
REVIEW
Silvia Ouakinin
INTRODUCTION: Teaching Psychology in medical curriculum has been the subject of numerous dissertations that focus on the relevance of this knowledge for doctors, at a general level. METHODS: A non-systematic review of the relevant literature, particularly from the last decade, as well as national and international recommendations addressing the need for integration of behavioural and social sciences in medical training, was performed. RESULTS: The literature supports the existence of preconceptions and negative attitudes towards the role of psychology in medical education, demonstrated by research in various european and american universities...
December 30, 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28424057/personalized-medicine-in-europe-not-yet-personal-enough
#7
Antonello Di Paolo, François Sarkozy, Bettina Ryll, Uwe Siebert
BACKGROUND: Personalized medicine has the potential to allow patients to receive drugs specific to their individual disease, and to increase the efficiency of the healthcare system. There is currently no comprehensive overview of personalized medicine, and this research aims to provide an overview of the concept and definition of personalized medicine in nine European countries. METHODS: A targeted literature review of selected health databases and grey literature was conducted to collate information regarding the definition, process, use, funding, impact and challenges associated with personalized medicine...
April 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28421750/how-frequently-are-pan-assay-interference-compounds-active-large-scale-analysis-of-screening-data-reveals-diverse-activity-profiles-low-global-hit-frequency-and-many-consistently-inactive-compounds
#8
Swarit Jasial, Ye Hu, Jürgen Bajorath
Undetected pan assay interference compounds (PAINS) with false-positive activities in assays often propagate through medicinal chemistry programs and compromise their outcome. Although a large number of PAINS have been classified, often on the basis of individual studies or chemical experience, little has been done so far to systematically assess their activity profiles. Herein, we report a large-scale analysis of the behaviour of PAINS in biological screening assays. More than 23,000 extensively tested compounds containing PAINS substructures were identified and their hit rates determined...
April 19, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28421338/tailoring-pharmacotherapy-to-specific-eating-behaviours-in-obesity-can-recommendations-for-personalised-therapy-be-made-from-the-current-data
#9
Carl A Roberts, Paul Christiansen, Jason C G Halford
Pharmacotherapy provides an adjunct to behaviour modification in the management of obesity. There are a number of new drug therapies purportedly targeting appetite; liraglutide, and bupropion/naltrexone, which are European Medicines Agency and US Food and Drug Administration (FDA) approved, and lorcaserin and phentermine/topiramate, which have FDA approval only. Each of the six drugs, used singly or in combination, has distinct pharmacological, and presumably distinct behavioural, mechanisms of action, thus the potential to provide defined therapeutic options to personalise the management of obesity...
April 19, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/28413365/integrating-the-principles-of-evidence-based-medicine-and-evidence-based-public-health-impact-on-the-quality-of-patient-care-and-hospital-readmission-rates-in-jordan
#10
Mohammad S Alyahya, Heba H Hijazi, Hussam A Alshraideh, Mohammad Aser Alsharman, Rabah Al Abdi, Heather Lea Harvey
INTRODUCTION: Hospital readmissions impose not only an extra burden on health care systems but impact patient health outcomes. Identifying modifiable behavioural risk factors that are possible causes of potentially avoidable readmissions can lower readmission rates and healthcare costs. METHODS: Using the core principles of evidence based medicine and public health, the purpose of this study was to develop a heuristic guide that could identify what behavioural risk factors influence hospital readmissions through adopting various methods of analysis including regression models, t-tests, data mining, and logistic regression...
August 31, 2016: International Journal of Integrated Care
https://www.readbyqxmd.com/read/28412219/medicinal-plant-uses-and-names-from-the-herbarium-of-francesc-bol%C3%A3-s-1773-1844
#11
Airy Gras, Teresa Garnatje, Neus Ibàñez, Jordi López-Pujol, Neus Nualart, Joan Vallè
ETHNOPHARMACOLOGICAL RELEVANCE: Ethnobotany takes into account past uses to be projected into the present and future. Most current ethnobotanical research is focused, especially in industrialised countries, on obtaining information of plant uses from elderly people. Historical ethnobotany is less cultivated, although papers have demonstrated its interest. Particularly poor, but potentially very relevant, is the attention paid to historical herbaria as a source of data on useful plants...
April 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28407198/chlorpromazine-dose-for-people-with-schizophrenia
#12
REVIEW
Katharine Dudley, Xiaomeng Liu, Saskia De Haan
BACKGROUND: The World Health Organization (WHO) Model Lists of Essential Medicines lists chlorpromazine as one of its five medicines used in psychotic disorders. OBJECTIVES: To determine chlorpromazine dose response and dose side-effect relationships for schizophrenia and schizophrenia-like psychoses. SEARCH METHODS: We searched the Cochrane Schizophrenia Group's Study-Based Register of Trials (December 2008; 2 October 2014; 19 December 2016)...
April 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28404722/evaluation-of-perceived-and-actual-competency-in-a-family-medicine-objective-structured-clinical-examination
#13
Lisa Graves, Leonora Lalla, Meredith Young
OBJECTIVE: To examine the relationship between objective assessment of performance and self-rated competence immediately before and after participation in a required summative family medicine clerkship objective structured clinical examination (OSCE). DESIGN: Learners rated their competence (on a 7-point Likert scale) before and after an OSCE along 3 dimensions: general, specific, and professional competencies relevant to family medicine. SETTING: McGill University in Montreal, Que...
April 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28404527/-when-you-are-homeless-you-are-not-thinking-about-your-medication-but-your-food-shelter-or-heat-for-the-night-behavioural-determinants-of-homeless-patients-adherence-to-prescribed-medicines
#14
V Paudyal, K MacLure, C Buchanan, L Wilson, J Macleod, D Stewart
OBJECTIVES: This study aimed to explore behavioural determinants of homeless patients' adherence to prescribed medicines using Theoretical Domains Framework (TDF). STUDY DESIGN: A qualitative study using semi-structured, face-to-face interviews. METHODS: Participants were recruited from a homelessness primary healthcare centre in Aberdeen, United Kingdom (UK). Face-to-face interviews were audio-recorded and transcribed verbatim. Thematic analysis of the interview data was conducted using the Framework Approach based on the Theoretical Domains Framework...
March 31, 2017: Public Health
https://www.readbyqxmd.com/read/28397317/evaluating-the-effectiveness-of-risk-minimisation-measures-the-application-of-a-conceptual-framework-to-danish-real-world-dabigatran-data
#15
REVIEW
Martin Erik Nyeland, Mona Vestergaard Laursen, Torbjörn Callréus
PURPOSE: For both marketing authorization holders and regulatory authorities, evaluating the effectiveness of risk minimization measures is now an integral part of pharmacovigilance in the European Union. The overall aim of activities in this area is to assess the performance of risk minimization measures implemented in order to ensure a positive benefit-risk balance in patients treated with a medicinal product. METHODS: Following a review of the relevant literature, we developed a conceptual framework consisting of four domains (data, knowledge, behaviour and outcomes) intended for the evaluation of risk minimization measures put into practice in the Danish health-care system...
April 11, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28387049/training-residents-in-depression-and-grief
#16
Angela Ghesquiere, Johanna Martinez, Cathy Jalali, Jo Anne Sirey, Susana Morales
BACKGROUND: About 20 per cent of Americans will experience depression in their lifetimes, and almost all will experience the death of a loved one. Both depression and grief have been associated with adverse health outcomes, including a decline in quality of life and excess mortality. Primary care physicians (PCPs) are the initial health care contact for most patients with depression and grief, yet often perceive that they lack the skills to adequately address these issues. Previous studies have investigated whether educational efforts improve PCP depression and grief knowledge or perceived skills, but few have focused on medical residents...
April 6, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28386916/identification-of-factors-that-may-influence-the-selection-of-first-line-biologic-therapy-for-people-with-psoriasis-a-prospective-multi-centre-cohort-study
#17
N J Davison, R B Warren, K J Mason, K McElhone, B Kirby, A D Burden, C H Smith, K Payne, C E M Griffiths
BACKGROUND: The Psoriasis Stratification to Optimise Relevant Therapy (PSORT) consortium has a collective aim to develop a prescribing algorithm to help stratify eligible psoriasis patients to the most appropriate biologic treatment. To facilitate the adoption of a stratified approach, it is necessary to first understand the factors driving the choice of first-line biologic therapy. OBJECTIVES: To identify and quantify factors which influence the selection of the first-line biologic therapy for people with psoriasis...
April 7, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28385098/pharmacological-evaluation-of-the-anxiolytic-like-effects-of-lippia-graveolens-and-bioactive-compounds
#18
María Eva González-Trujano, Laura Yunuen Hernández-Sánchez, Verónica Muñoz Ocotero, Alejandro Dorazco-González, Patricia Guevara Fefer, Eva Aguirre-Hernández
CONTEXT: Lippia species (Verbenaceae) are widely used in Latin America and Africa as folk medicine for their tranquilizing properties. OBJECTIVE: To evaluate the anxiolytic-like effects and safety of Lippia graveolens Kunth. by exploring its aqueous and organic leaf extracts and identifying the responsible chemical constituents. MATERIAL AND METHODS: Aqueous and organic extracts (hexane, ethyl acetate and methanol) were pharmacologically evaluated at several doses...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28382769/the-blindfolded-code-training-exercise
#19
Rami Ahmed, Kate Hughes, Patrick Hughes
BACKGROUND: Communication errors are the leading cause of preventable patient harm in medicine. There is little description in the literature of advanced techniques to teach crisis resource management (CRM) communication strategies, or how to improve real-time ineffective behaviour or habits that may persist despite appropriate behaviour and leadership witnessed in the simulation lab. CONTEXT: This article presents an advanced teaching technique to force the adoption of closed-loop communication strategies...
April 5, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28379415/adaptation-to-european-spanish-and-psychometric-properties-of-the-patient-activation-measure-13-in-patients-with-chronic-diseases
#20
Cibeles Moreno-Chico, Luis González-de Paz, Cristina Monforte-Royo, Emilia Arrighi, M Dolores Navarro-Rubio, Alberto Gallart Fernández-Puebla
Background: . The 13-item Patient Activation Measure (PAM-13) is an instrument that assesses people's knowledge, skills and confidence for self-management of their health and health care. Scores on the PAM-13 have been shown to predict adherence to health behaviours, health-related outcomes and health care costs. Objectives: . To develop a European Spanish adaptation of the original PAM-13 and to examine its psychometric properties in a sample of chronic patients...
March 31, 2017: Family Practice
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