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cigarette and acne

Hyunsung Park, Jae Jun Park, Yoo Mi Park, Su Jung Baik, Hyun Ju Lee, Da Hyun Jung, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park
BACKGROUND: The association between Helicobacter pylori infection and advanced colorectal neoplasia (ACN) remains controversial. This study aimed to clarify the association between H. pylori infection and ACN according to age groups. METHODS: We retrospectively analyzed the association between H. pylori infection and ACN in patients aged <50 and ≥50 years receiving a health checkup that included colonoscopy. Helicobacter pylori positivity was determined by the results of serum anti-H...
March 29, 2018: Helicobacter
Roshni Bhudia, Amar Ahmad, Onyinye Akpenyi, Angela Whiley, Mark Wilks, Tim Oliver
The microaerophylic organism Propionibacterium acnes has shown consistent association with prostate cancer (PC). Studies linking circumcision with reduced PC further support anaerobes involvement as circumcision reduces anaerobe colonisation on the glans penis. A 1988 study linked anaerobes with PC but considered them as opportunists in necrotic tumour. A hypothesis that a "Helicobacter-like" process causes PC justified this pilot study. Active surveillance patients were enrolled. Post-prostate massage urine samples were screened using the Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) technique for bacterial identification after culture in anaerobic and aerobic conditions...
November 9, 2017: Scientific Reports
Poonam Puri, Shashi Kumar Nandar, Sushruta Kathuria, V Ramesh
The increase in air pollution over the years has had major effects on the human skin. Various air pollutants such as ultraviolet radiation, polycyclic aromatic hydrocarbons, volatile organic compounds, oxides, particulate matter, ozone and cigarette smoke affect the skin as it is the outermost barrier. Air pollutants damage the skin by inducing oxidative stress. Although human skin acts as a biological shield against pro-oxidative chemicals and physical air pollutants, prolonged or repetitive exposure to high levels of these pollutants may have profound negative effects on the skin...
July 2017: Indian Journal of Dermatology, Venereology and Leprology
Ilaria Crivellari, Claudia Sticozzi, Giuseppe Belmonte, Ximena M Muresan, Franco Cervellati, Alessandra Pecorelli, Carlotta Cavicchio, Emanuela Maioli, Christos C Zouboulis, Mascia Benedusi, Carlo Cervellati, Giuseppe Valacchi
For its critical location, the skin represents the major interface between the body and the environment, therefore is one of the major biological barriers against the outdoor environmental stressors. Among the several oxidative environmental stressors, cigarette smoke (CS) has been associated with the development and worsening of many skin pathologies such as acne, dermatitis, delayed wound healing, aging and skin cancer. In our previous work we have demonstrated that CS is able to affect genes involved in skin cholesterol trafficking, among which SRB1, a receptor involved in the uptake of cholesterol from HDL, seems to be very susceptible to the oxidative stress induced by CS...
January 2017: Free Radical Biology & Medicine
Xiaoming Cai, Ruibin Li
Blood plasma is the most popularly used sample matrix for metabolite profiling studies, which aim to achieve global metabolite profiling and biomarker discovery. However, most of the current studies on plasma metabolite profiling focused on either the polar metabolites or lipids. In this study, a comprehensive analysis approach based on HILIC-FTMS was developed to concurrently examine polar metabolites and lipids. The HILIC-FTMS method was developed using mixed standards of polar metabolites and lipids, the separation efficiency of which is better in HILIC mode than in C5 and C18 reversed phase (RP) chromatography...
November 7, 2016: Scientific Reports
Shouai Feng, Kang Wei, Zhaofu Tian, Xiaolan Li, Dongling Meng, Wenlong Liao, Mingming Miao, Yaling Yang
In this work, a simple and effective method based on magnetic solid-phase extraction combined with high-performance liquid chromatography was developed for the determination of benzo[α]pyrene (BaP) in cigarette smoke. Oleic acid coated Fe3O4 (Fe3O4-OA) was synthesized and directly used as an efficient sorbent for the first time in magnetic solid-phase extraction (MSPE) procedure for the clean-up of BaP in cigarette smoke extracts. The synthesized Fe3O4-OA was characterized by transmission electron microscopy, X-ray diffraction and Fourier transformed infrared spectroscopy...
July 29, 2016: Journal of Chromatographic Science
Aayush Gupta, Yugal Kishor Sharma, Kedar Nath Dash, Nitin Dinkar Chaudhari, Sumit Jethani
BACKGROUND: Acne vulgaris is known to impair many aspects of quality of life. However, the correlation of this impairment with clinical severity remains equivocal despite various school, community and hospital-based studies. AIM: A hospital-based study was undertaken to measure the impairment of quality of life of patients of acne vulgaris and correlate it with the severity of lesions. METHODS: This was a cross-sectional, questionnaire-based study in a cohort of 100 patients of acne vulgaris attending the outpatient department of our referral hospital...
May 2016: Indian Journal of Dermatology, Venereology and Leprology
Aayush Gupta, Yugal Kishor Sharma, Kedar Nath Dash, Nitin Dinkar Chaudhari, Sumit Jethani
BACKGROUND: Acne vulgaris is known to impair many aspects of quality of life. However, the correlation of this impairment with clinical severity remains equivocal despite various school, community and hospital-based studies. AIM: A hospital-based study was undertaken to measure the impairment of quality of life of patients of acne vulgaris and correlate it with the severity of lesions. METHODS: This was a cross-sectional, questionnaire-based study in a cohort of 100 patients of acne vulgaris attending the outpatient department of our referral hospital...
January 14, 2016: Indian Journal of Dermatology, Venereology and Leprology
Errol Prens, Inge Deckers
The pathogenesis of hidradenitis suppurativa (HS) or acne inversa is not completely understood. Recent research has led to greater insight into the mechanisms involved in the disease. The primary defect in HS pathophysiology rests with the hair follicle. Follicular occlusion, followed by follicular rupture, and a foreign body-type immune response are necessary conditions for the development of clinical HS. A specific genetic signature and environmental factors, such as cigarette smoking, microbial colonization, and adiposity, all contribute to the HS phenotype...
November 2015: Journal of the American Academy of Dermatology
Andrew T Patterson, Frances T Tian, Dirk M Elston, Benjamin H Kaffenberger
Many environmental acne disorders, including chloracne and oil acne, were previously thought to occur predominantly in occupational settings following polycyclic aromatic hydrocarbon exposure. Cigarette smoke has also been shown to contain a large number of these toxic polycyclic aromatic hydrocarbon components and strictly correlates with noninflammatory acneiform lesion development in postadolescent patients. We report a case of localized open comedones associated with occluded cigarette smoke exposure near the nasal cavity due to infrequently changed gauze following rhinectomy...
2015: Dermatology: International Journal for Clinical and Investigative Dermatology
Ozlem Ekiz, Ilknur Balta, Ezgi Unlu, Bilge Bulbul Sen, Emine N Rifaioğlu, Asena C Dogramaci
BACKGROUND: Postadolescent acne is defined as acne that is seen even after the age of 25 years, regardless of the age at onset. The causes of postadolescent acne have not been completely clarified up to now. Androgens are considered to be the major factor involved in pathogenesis. OBJECTIVE: We aimed to investigate the status of thyroid functions and lipid levels in patients with postadolescent acne and determine the effects of lifestyle and environmental factors on postadolescent acne in a Turkish population...
December 2015: International Journal of Dermatology
D-M Pham, B Boussouira, D Moyal, Q L Nguyen
A review of the oxidization of squalene, a specific human compound produced by the sebaceous gland, is proposed. Such chemical transformation induces important consequences at various levels. Squalene by-products, mostly under peroxidized forms, lead to comedogenesis, contribute to the development of inflammatory acne and possibly modify the skin relief (wrinkling). Experimental conditions of oxidation and/or photo-oxidation mechanisms are exposed, suggesting that they could possibly be bio-markers of atmospheric pollution upon skin...
August 2015: International Journal of Cosmetic Science
Pierre Wolkenstein, Laurent Misery, Jean-Michel Amici, Rémi Maghia, Sébastien Branchoux, Christine Cazeau, Jean-Jacques Voisard, Charles Taïeb
BACKGROUND: Dietary factors and smoking play a role in acne. METHODS: CSA Santé conducted a survey in France in 2012. Each individual answered a questionnaire to report acne, with associated epidemiological variables. Data on subjects between 15 and 24 years of age were extracted. The characteristics of subjects reporting acne were compared to subjects reporting no acne, using univariate and multivariate analysis. RESULTS: The daily consumption of chocolate and sweets was independently and highly associated with acne, with an odds ratio of 2...
2015: Dermatology: International Journal for Clinical and Investigative Dermatology
Noah Scheinfeld
This article is dermatological atlas of the morphologic presentations of Hidradenitis Suppurativa (HS). It includes: superficial abscesses (boils, furnucles, carbuncles), abscesses that are subcutaneous and suprafascial, pyogenic granulomas, cysts, painful erythematous papules and plaques, folliculitis, open ulcerations, chronic sinuses, fistulas, sinus tracts, scrotal and genital lyphedema, dermal contractures, keloids (some that are still pitted with follicular ostia), scarring, skin tags, fibrosis, anal fissures, fistulas (i...
April 16, 2014: Dermatology Online Journal
Yun Seok Yang, Hee Kyeong Lim, Kyung Kook Hong, Min Kyung Shin, Jin Woo Lee, Sung Won Lee, Nack-In Kim
BACKGROUND: Lipid peroxide (LPO) in comedones, which are produced as a result of sebum oxidation, might potentially induce interleukin-1α (IL-1α) and exacerbate comedogenesis and inflammatory changes in comedones. OBJECTIVE: To investigate the relationship of proinflammatory cytokines and LPO levels in the extracts of comedones with the acne of clinical difference between smokers and non-smokers, and with the severity and distribution of the acne lesions. METHODS: Twenty-two non-smoking and 21 smoking adult acne patients were evaluated by comedone extraction and measurement of proinflammatory cytokines and LPO levels...
February 2014: Annals of Dermatology
S G Bilgili, H U Ozkol, A S Karadag, O Calka
INTRODUCTION: Over the past decade, complementary and alternative medicine (CAM) has become increasingly popular around the world. OBJECTIVES: In this study, we aim to investigate how frequently CAM is used and the types of CAM methods used for dermatological disease in Eastern Turkey. MATERIALS AND METHODS: We recruited 1610 patients from our clinic for this study. The sociodemographic features and the CAM methods were investigated with a survey...
February 2014: Human & Experimental Toxicology
L B Håkonsen, J Olsen, H Støvring, A Ernst, A M Thulstrup, J L Zhu, A Shrestha, C H Ramlau-Hansen
Epidemiological studies have raised concern about the reproductive consequences of prenatal cigarette smoking exposure, possibly affecting semen quality and onset of pubertal development of the offspring. The aim of this study was to further investigate pubertal development in young men exposed to cigarette smoking in foetal life. In a Danish pregnancy cohort, information on maternal smoking during pregnancy was available from questionnaires administered in 1984-1987, and information on pubertal development, assessed by age at first nocturnal emission, acne, voice break and regular shaving, was obtained from a follow-up questionnaire administered in 2005 to the young men (age: 18-21)...
March 2013: Andrology
Florence Poli, Nicole Auffret, Claire Beylot, Martine Chivot, Michel Faure, Dominique Moyse, Henri Pawin, Jean Revuz, Brigitte Dréno
Acne can have an important psychological impact. We surveyed 852 adolescents aged 12-25 years about their knowledge of acne and its treatment in a non-medical context. The study involved a questionnaire administered to callers to a youth telephone helpline in France. Callers were categorized into those who currently had acne, those who had had acne previously, and those who had never had acne. Most respondents (66.2%) had experienced acne symptoms, which were mild in 50.2% of cases and severe in 16% of cases...
September 2011: Acta Dermato-venereologica
Gaku Tsuji, Masakazu Takahara, Hiroshi Uchi, Satoshi Takeuchi, Chikage Mitoma, Yoichi Moroi, Masutaka Furue
BACKGROUND: Benzo(a)pyrene (BaP) is an environmental contaminant found in cigarette smoke. It is well known that cigarette smoking exacerbates interleukin-8 (IL-8)-related inflammatory skin diseases such as psoriasis, palmoplantar pustulosis and acne. Although BaP has been shown to exert its biological effects via the aryl hydrocarbon receptor (AhR) signaling pathway, the mechanism of its inflammatory effects on skin remains unanswered. OBJECTIVE: To elucidate whether or not BaP cause AhR activation and subsequent oxidative stress leading to IL-8 production in normal human epidermal keratinocytes (NHEKs)...
April 2011: Journal of Dermatological Science
B Dréno
The prevalence of acne is about 80% in the majority of the countries worldwide. Moderate and severe acne account for 20% of all cases. Prognostic factors of acne severity were identified: hyper seborrhea, an age of beginning of acne after 17 years or pre pubertray, extension of acne lesions to the trunk, stress for the two sexes, and notion of family acne (hereditary). The role of cigarette and food remains discussed. Acne of the adult (man and woman) is in increase and is estimated at 40% of the adults. In addition, recent epidemiologic data reveal that the acneic subject consults little the doctor (on average, one out of two) and, in the same way, only one young person out of two teenagers declaring a severe acne is treated...
November 2010: Annales de Dermatologie et de Vénéréologie
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