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https://www.readbyqxmd.com/read/29913269/iliac-screw-for-reconstructing-posterior-pelvic-ring-in-tile-type-c1-pelvic-fractures
#1
Yonggang Li, Xiguang Sang, Zhiyong Wang, Lin Cheng, Hao Liu, Tao Qin, Kai Di
BACKGROUND: It is often difficult to achieve stable fixation in Tile type C1 pelvic fractures and there is no standard fixation technique for these types of injuries. HYPOTHESIS: Iliac screw fixation can be used for treating Type C1 pelvic fractures. PATIENTS AND METHODS: A retrospective review was performed on 47 patients who underwent iliac screw fixation in posterior column of ilium (PCI) for Tile type C1 pelvic fractures from July 2007 to December 2014...
June 15, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29885047/in-long-bacterial-cells-the-min-system-can-act-off-center
#2
Joshua S MacCready, Anthony G Vecchiarelli
In many rod-shaped bacteria, the Min system is well known for generating a cell-pole to cell-pole standing wave oscillation with a single node at mid-cell to align cell division. In filamentous E. coli cells, the single-node standing wave transitions into a multi-nodal oscillation. These multi-nodal dynamics have largely been treated simply as an interesting byproduct of artificially elongated cells. However, a recent in vivo study by Muraleedharan et al. shows how multi-nodal Min dynamics are used to align non-mid-cell divisions in the elongated swarmer cells of Vibrio parahaemolyticus (in press)...
June 8, 2018: Molecular Microbiology
https://www.readbyqxmd.com/read/29864352/controlling-nanoantenna-polarizability-through-backaction-via-a-single-cavity-mode
#3
Freek Ruesink, Hugo M Doeleman, Ewold Verhagen, A Femius Koenderink
The polarizability α determines the absorption, extinction, and scattering by small particles. Beyond being purely set by scatterer size and material, in fact polarizability can be affected by backaction: the influence of the photonic environment on the scatterer. As such, controlling the strength of backaction provides a tool to tailor the (radiative) properties of nanoparticles. Here, we control the backaction between broadband scatterers and a single mode of a high-quality cavity. We demonstrate that backaction from a microtoroid ring resonator significantly alters the polarizability of an array of nanorods: the polarizability is renormalized as fields scattered from-and returning to-the nanorods via the ring resonator depolarize the rods...
May 18, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29858499/direction-modulated-brachytherapy-dmbt-tandem-applicator-for-cervical-cancer-treatment-choosing-the-optimal-shielding-material
#4
Habib Safigholi, Dae Yup Han, Abraam Soliman, William Y Song
PURPOSE: To investigate the dose modulation capability of a novel MRI-compatible Direction Modulated Brachytherapy (DMBT) tandem applicator design with various high density shielding materials for brachytherapy treatment of cervical cancer. The shield materials that have been evaluated are tantalum (Ta), pure tungsten (W), gold (Au), rhenium (Re), osmium (Os), platinum (Pt), iridium (Ir), and W' tungsten-alloy (95%W, 3.5%Ni, 1.5%Cu). MATERIALS AND METHODS: The recently proposed six-channel DMBT tandem is composed of non-magnetic tungsten alloy (W') rod with diameter of 5...
June 2, 2018: Medical Physics
https://www.readbyqxmd.com/read/29806335/-development-and-current-situation-of-reconstruction-methods-following-total-sacrectomy
#5
Siyi Huang, Tao Ji, Wei Guo
Objective: To review the development of the reconstruction methods following total sacrectomy, and to provide reference for finding a better reconstruction method following total sacrectomy. Methods: The case reports and biomechanical and finite element studies of reconstruction following total sacrectomy at home and abroad were searched. Development and current situation were summarized. Results: After developing for nearly 30 years, great progress has been made in the reconstruction concept and fixation techniques...
May 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29789819/exploring-the-cellular-uptake-and-localisation-of-phosphorescent-rhenium-fac-tricarbonyl-metallosurfactants-as-a-function-of-lipophilicity
#6
Andrew J Hallett, Emeline Placet, Roxane Prieux, Danielle McCafferty, James A Platts, David Lloyd, Marc Isaacs, Anthony J Hayes, Simon J Coles, Mateusz B Pitak, Sarah Marchant, Stephen N Marriott, Rudolf K Allemann, Athanasia Dervisi, Ian A Fallis
A systematic study of the cellular uptake of emissive complexes as a function of their lipophilicity is presented. Here a series of amphiphilic rhenium fac-tricarbonyl bisimine complexes bearing axial substituted imidazole or thiazole ligands, [Re(bpy)(CO)3(ImCnHm)]+ {n = 1 m = 3 (1+), n = 4 m = 9 (2+), n = 8 m = 17 (3+), n = 12 m = 25 (4+), n = 16 m = 33 (5+), n = 2 m = 3 (6+); bpy = 2,2'-bipyridine, Im = imidazole} and [Re(bpy)(CO)3(L)]+ {L = 1-mesitylimidazole, ImMes (7+), 4,5-dimethylthiazole, dmt (8+) and 4-methyl-5-thiazole-ethanol, mte (9+)} is reported...
May 23, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29785590/clinical-application-of-a-minimally-invasive-cement-augmentable-schanz-screw-rod-system-to-treat-pelvic-ring-fractures
#7
Paul Schmitz, Florian Baumann, Yves P Acklin, Boyko Gueorguiev, Michael Nerlich, Stephan Grechenig, Michael Bernd Müller
PURPOSE: The purpose of this study is to analyze the results using the USS fracture MIS system (DePuy Synthes) to treat instable pelvic ring fractures. As its outstanding feature, it is the only Schanz screw and rod system at present that combines angular stability, perforation/fenestration of the screws for cement-augmentation, a variable screw length, and a large screw diameter. MATERIALS AND METHODS: Retrospective investigation of 134 pelvic ring fractures treated in 2012-2013...
May 21, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29741202/identification-of-protein-kinase-c-%C3%AE-and-tyrosine-hydroxylase-immunoreactive-cells-in-the-microbat-retina
#8
Eun-Bee Park, Joo-Yeong Jeon, Chang-Jin Jeon
A growing number of studies have revealed the functional neuroarchitecture of the microbat retina and suggested that microbats can see using their eyes. To better understand the organization of the microbat retina, quantitative analysis of protein kinase C alpha (PKCα)- and tyrosine hydroxylase (TH)-immunoreactive (IR) cells was conducted on the greater horseshoe bat (Rhinolophus ferrumequinum) retina. As a result, PKCα immunoreactivity was observed in rod bipolar cells, consistent with previous studies on other mammalian retinas...
May 9, 2018: Histology and Histopathology
https://www.readbyqxmd.com/read/29733648/inverse-thermoreversible-mechanical-stiffening-and-birefringence-in-methylcellulose-cellulose-nanocrystal-hydrogel
#9
Ville Hynninen, Sami Hietala, Jason Robert McKee, Lasse Murtomäki, Orlando J Rojas, Olli Ikkala, Nonappa Nonappa
We show that composite hydrogels comprising methyl cellulose (MC) and cellulose nanocrystal (CNC) colloidal rods display a reversible and enhanced rheological storage modulus and optical birefringence upon heating, i.e., inverse thermoreversibility. Dynamic rheology, quantitative polarized optical microscopy (POM), isothermal titration calorimetry (ITC), circular dichroism (CD), and scanning and transmission electron microscopy (SEM and TEM) were used for characterization. The concentration of CNC in aqueous media was varied up to 3...
May 7, 2018: Biomacromolecules
https://www.readbyqxmd.com/read/29724956/structure-of-the-dash-dam1-complex-shows-its-role-at-the-yeast-kinetochore-microtubule-interface
#10
Simon Jenni, Stephen C Harrison
Kinetochores connect mitotic-spindle microtubules with chromosomes, allowing microtubule depolymerization to pull chromosomes apart during anaphase while resisting detachment as the microtubule shortens. The heterodecameric DASH/Dam1 complex (DASH/Dam1c), an essential component of yeast kinetochores, assembles into a microtubule-encircling ring. The ring associates with rodlike Ndc80 complexes to organize the kinetochore-microtubule interface. We report the cryo-electron microscopy structure (at ~4.5-angstrom resolution) of a DASH/Dam1c ring and a molecular model of its ordered components, validated by evolutionary direct-coupling analysis...
May 4, 2018: Science
https://www.readbyqxmd.com/read/29713038/motorizing-fibres-with-geometric-zero-energy-modes
#11
Arthur Baumann, Antoni Sánchez-Ferrer, Leandro Jacomine, Philippe Martinoty, Vincent Le Houerou, Falko Ziebert, Igor M Kulić
Responsive materials1-3 have been used to generate structures with built-in complex geometries4-6 , linear actuators7-9 and microswimmers10-12 . These results suggest that complex, fully functional machines composed solely from shape-changing materials might be possible 13 . Nonetheless, to accomplish rotary motion in these materials still relies on the classical wheel and axle motifs. Here we explore geometric zero-energy modes to elicit rotary motion in elastic materials in the absence of a rigid wheel travelling around an axle...
April 30, 2018: Nature Materials
https://www.readbyqxmd.com/read/29694781/composite-reinforcement-by-magnetic-control-of-fiber-density-and-orientation
#12
Omri Goldberg, Israel Greenfeld, H Daniel Wagner
The flexural rigidity of cylindrical specimens, composed of epoxy reinforced by short, magnetized glass fibers, was enhanced using weak magnetic fields (<100 mT). By spatially controlling the magnitude and direction of the field, and thereby the torques and forces acting locally on the fibers, the orientation and concentration of the fillers in the matrix could be tuned prior to curing. Unidirectional alignment of the fibers, achieved using an air-core solenoid, improved the contribution of the fibers to the flexure modulus by a factor of 3...
May 16, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29691705/retinal-dysfunction-in-a-presymptomatic-patient-with-huntington-s-disease
#13
Jonelle Knapp, Dean A VanNasdale, Keith Ramsey, Julie Racine
PURPOSE: Huntington's disease (HD) is an autosomal dominant, neurodegenerative disorder characterized by progressive motor dysfunction, cognitive decline, and psychiatric disturbances. Studies have shown retinal abnormalities in patients and mouse models with HD; however, to our knowledge, no prior research papers evaluated retinal structure and function in a presymptomatic patient with HD. The aim of this report is to present a case of retinal dysfunction in a presymptomatic patient with HD...
April 24, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29676528/e3-ubiquitin-ligase-rnf123-targets-lamin-b1-and-lamin-binding-proteins
#14
Richa Khanna, Vidhya Krishnamoorthy, Veena K Parnaik
Lamins are key nuclear proteins which are important for maintaining nuclear structure and function. Mutations in lamins cause a spectrum of genetic diseases termed as laminopathies. RING finger containing E3 ubiquitin ligase, RNF123, is transcriptionally upregulated in cells expressing rod domain lamin A mutations. However, the functional relevance of RNF123 in laminopathic cells is not clear. Using a mass spectrometry-based approach, we identified lamins and lamin-binding proteins retinoblastoma protein (pRb), lamina-associated polypeptide 2α (LAP2α), and emerin as RNF123-interacting proteins...
April 20, 2018: FEBS Journal
https://www.readbyqxmd.com/read/29671671/progressive-expansion-of-the-hyperautofluorescent-ring-in-cone-rod-dystrophy-patients
#15
Luiz H Lima, Claudio Zett, Vinícius Kniggendorf, Bruna Marianelli, Ricardo A P de Carvalho, Michel E Farah, Juliana M F Sallum
PURPOSE: To evaluate the expansion of the hyperautofluorescent ring and the retinal structure changes over time in cone-rod dystrophy (CRD) patients, using fundus autofluorescence (FAF) and spectral-domain optical coherence tomography (SD-OCT). METHODS: Retrospective case series study. Six eyes of three CRD patients with a parafoveal hyperautofluorescent ring were studied. The diagnosis of CRD was established by the presence of the implicit time shift at 30-Hz flicker and prevalent decrease of photopic over scotopic responses on electroretinography...
April 19, 2018: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29665440/mri-compatible-ms2-nanoparticles-designed-to-cross-the-blood-brain-barrier-providing-a-path-towards-tinnitus-treatment
#16
Aaron K Apawu, Stephanie M Curley, Angela R Dixon, Mirabela Hali, Moaz Sinan, Rod D Braun, James Castracane, Anthony T Cacace, Magnus Bergkvist, Avril Genene Holt
Fundamental challenges of targeting specific brain regions for treatment using pharmacotherapeutic nanoparticle (NP) carriers include circumventing the blood-brain-barrier (BBB) and tracking delivery. Angiopep-2 (AP2) has been shown to facilitate the transport of large macromolecules and synthetic nanoparticles across the BBB. Thus, conjugation of AP2 to an MS2 bacteriophage based NP should also permit transport across the BBB. We have fabricated and tested a novel MS2 capsid-based NP conjugated to the ligand AP2...
April 14, 2018: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29656527/self-assembly-of-rod-coil-block-copolymers-on-carbon-nanotubes-a-route-toward-diverse-surface-nanostructures
#17
Yang Han, Chunhua Cai, Jiaping Lin, Shuting Gong, Wenheng Xu, Rui Hu
In this work, it is reported that poly(γ-benzyl-l-glutamate)-block-poly(ethylene glycol) (PBLG-b-PEG) rod-coil block copolymers (BCPs) can disperse carbon nanotubes (CNTs) in solution and form various surface nanostructures on the CNTs via solution self-assembly. In an organic solvent that dissolves the BCPs, the PBLG rod blocks adsorb on CNT surfaces, and the BCPs form conformal coatings. Then, by the introduction of water, a selective solvent for PEG blocks, the BCPs in the coatings further self-assemble into diverse surface nanostructures, such as helices (left-handed or right-handed), gyros, spheres, and rings...
May 2018: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29610277/the-cell-division-protein-mind-from-pseudomonas-aeruginosa-dominates-the-assembly-of-the-minc-mind-copolymers
#18
Haiyan Huang, Ping Wang, Li Bian, Masaki Osawa, Harold P Erickson, Yaodong Chen
Cell division of rod-shaped bacteria requires the Z ring, a ring of FtsZ filaments associated with the inner-membrane wall. The MinCDE proteins help localize the Z ring to the center of the Escherichia coli cell. MinC, which inhibits Z-ring assembly, is a passenger on MinD. Previous studies have shown that MinC-MinD from E. coli and Aquifex aeolicus assemble in vitro into extended filaments with a 1:1 stoichiometry. However, a recent study has raised questions about the function of the MinC-MinD copolymer in vivo , because its assembly appears to require a high concentration of these two proteins and has a long lag time, and its blockade does not affect in vivo activities...
May 18, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29604020/ultra-fast-all-optical-decoder-based-on-nonlinear-photonic-crystal-ring-resonators
#19
Tina Daghooghi, Mohammad Soroosh, Karim Ansari-Asl
In this paper, a 2-to-4 all-optical decoder based on photonic crystal ring resonators is introduced. The photonic crystal structure has a 2D square chalcogenide rod lattice whose maximum response time is 2 ps. Three ring resonators including nonlinear rods with 9×10-17   m2 /W for a Kerr coefficient carry out a switching operation at 1550 nm wavelength. The switching speed of the device is 500 GHz, which is more than that in previously presented works. Also, the small size of the structure is sufficient for optical integrated circuits...
March 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29565439/ph-induced-evolution-of-surface-patterns-in-micelles-assembled-from-dirhamnolipids-dissipative-particle-dynamics-simulation
#20
Jianchang Xu, Shuangqing Sun, Zhikun Wang, Shiyuan Peng, Songqing Hu, Lijuan Zhang
Dissipative particle dynamics (DPD) simulation is used to study the effect of pH on the morphological transition in micelles assembled from dirhamnolipids (diRLs), and analyze the pH-driven mechanism and influence factors of micellar surface patterns. At pH < 4.0, various multilayer structures with homogeneous surface patterns are observed, whereas diRLs can self-assemble into novel anisotropic morphologies with phase-separated surface patterns at pH > 7.4, such as patchy spherical micelles, rod-like micelles with helical surface patterns and a lamellar phase with anisotropic surface patterns...
April 4, 2018: Physical Chemistry Chemical Physics: PCCP
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