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https://www.readbyqxmd.com/read/29238871/minimally-invasive-stabilisation-of-posterior-pelvic-ring-instabilities-with-pedicle-screws-connected-to-a-transverse-rod
#1
Hu Wang, Ya-Hui Fu, Chao Ke, Yan Zhuang, Kun Zhang, Xing Wei, Zhong Li, Jin-Lai Lei, Bin-Fei Zhang, Ping Liu
PURPOSE: The goal was to evaluate the clinical outcomes, quality of reduction and complications of pelvic fractures treated by minimally invasive stabilisation of posterior pelvic ring instabilities with pedicle screws connected to a transverse rod. METHODS: Retrospective analysis of prospectively collected data in a consecutive patient series with pelvic fractures treated by minimally invasive stabilisation of posterior pelvic ring instabilities with pedicle screws between January 2010 and January 2016...
December 14, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29216149/on-chip-wavelength-locking-for-photonic-switches
#2
Akhilesh S P Khope, Takako Hirokawa, Andrew M Netherton, Mitra Saeidi, Yujie Xia, Nicolas Volet, Clint Schow, Roger Helkey, Luke Theogarajan, Adel A M Saleh, John E Bowers, Rod C Alferness
We present an on-chip wavelength reference with a partial drop ring resonator and germanium photodetector. This approach can be used in ring-resonator-based wavelength-selective switches where absolute wavelength alignment is required. We use the temperature dependence of heater resistance as a temperature sensor. Additionally, we discuss locking speed, statistical variation of heater resistances, and tuning speed of the switches.
December 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/29205883/fission-yeast-myo2-molecular-organization-and-diffusion-in-the-cytoplasm
#3
Janice E Friend, Wasim A Sayyad, Rajesh Arasada, Chad D McCormick, John E Heuser, Thomas D Pollard
Myosin-II is required for the assembly and constriction of cytokinetic contractile rings in fungi and animals. We used electron microscopy, fluorescence recovery after photobleaching (FRAP), and fluorescence correlation spectroscopy (FCS) to characterize the physical properties of Myo2 from fission yeast Schizosaccharomyces pombe. By electron microscopy, Myo2 has two heads and a coiled-coiled tail like myosin-II from other species. The first 65 nm of the tail is a stiff rod, followed by a flexible, less-ordered region up to 30 nm long...
December 4, 2017: Cytoskeleton
https://www.readbyqxmd.com/read/29191213/modified-pedicle-screw-rod-fixation-versus-anterior-pelvic-external-fixation-for-the-management-of-anterior-pelvic-ring-fractures-a-comparative-study
#4
Chun Bi, Qiugen Wang, Jianhong Wu, Feng Zhou, Fei Zhang, Haipeng Liang, Fei Lyu, Jiandong Wang
BACKGROUND: Anterior pelvic ring fracture, as high-energy trauma, needs to be effectively treated. The purpose of the current study was to evaluate the clinical applications of modified pedicle screw-rod fixation and anterior pelvic external fixation for the treatment of anterior pelvic ring fracture. METHODS: Either modified pedicle screw-rod fixation (modified PSRF group, N = 21) or anterior pelvic external fixation (APEF group, N = 22) was performed to 43 patients, with or without fixation of posterior ring...
December 1, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29181464/exploration-of-cell-division-times-during-bacterial-cytokinesis
#5
Zi He, Kunkun Guo
Filamenting temperature-sensitive mutant Z (FtsZ), an essential cell division protein in bacteria, has recently emerged as an important and exploitable antibacterial target. The perturbation of FtsZ assembly is found to have an effect on cell cytokinesis and cell survival. Cell division time is an important physical parameter in cell cytokinesis. Here, the theoretical framework that has been developed by combining a phase field model for rod-shaped cells with a kinetic description for FtsZ ring maintenance is extended to explore cell division times during bacterial cytokinesis...
November 28, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29176772/symphyseal-fixation-in-open-book-injuries-cannot-fully-compensate-anterior-si-joint-injury-a-biomechanical-study-in-a-two-leg-alternating-load-model
#6
Fabian M Stuby, Mark Lenz, Stefan Doebele, Yash Agarwal, Hristo Skulev, Björn G Ochs, Jörn Zwingmann, Boyko Gueorguiev
INTRODUCTION: In open book injuries type Tile B1.1 or B1.2 also classified as APC II (anteroposterior compression), it remains controversial, if a fixation of the anterior ring provides sufficient stability or a fixation of the posterior ring should be included. Therefore the relative motion at the sacroiliac joint was quantified in a two-leg alternating load biomechanical pelvis model in the intact, the injured and the restored pelvis. METHODS: Fresh-frozen intact (I) pelvises (n = 6) were subjected to a non-destructive cyclic test under sinosuidal axial two-leg alternating load with progressively increasing amplitude...
2017: PloS One
https://www.readbyqxmd.com/read/29176531/autoimmune-retinopathy-in-a-patient-with-a-missense-mutation-in-pitpnm3
#7
Mathieu F Bakhoum, Jesse D Sengillo, Xuan Cui, Stephen H Tsang
PURPOSE: To describe a patient with a PITPNM3 missense mutation who developed late-onset autoimmune retinopathy. METHODS: Case report. RESULTS: An 85-year-old man presented with decreased vision, nyctalopia, and photoaversion after an uncomplicated cataract surgery. Multimodal retinal imaging revealed a scalloped pattern of atrophy and a ring of hyperautofluorescence in the perifoveal area on fundus autofluorescence. Spectral domain optical coherence tomography demonstrated loss of the ellipsoid band, along with outer retinal atrophy, sparing the fovea in both eyes...
November 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29167284/molecular-structures-of-yeast-kinetochore-subcomplexes-and-their-roles-in-chromosome-segregation
#8
Simon Jenni, Yoana N Dimitrova, Roberto Valverde, Stephen M Hinshaw, Stephen C Harrison
Kinetochore molecular architecture exemplifies "form follows function." The simplifications that generated the one-chromosome:one-microtubule linkage in point-centromere yeast have enabled strategies for systematic structural analysis and high-resolution visualization of many kinetochore components, leading to specific proposals for molecular mechanisms. We describe here some structural features that allow a kinetochore to remain attached to the end of a depolymerizing microtubule (MT) and some characteristics of the connections between substructures that permit very sensitive regulation by differential kinase activities...
November 22, 2017: Cold Spring Harbor Symposia on Quantitative Biology
https://www.readbyqxmd.com/read/29162705/three-dimensional-superresolution-imaging-of-the-ftsz-ring-during-cell-division-of-the-cyanobacterium-prochlorococcus
#9
Riyue Liu, Yaxin Liu, Shichang Liu, Ying Wang, Kim Li, Ning Li, Daiying Xu, Qinglu Zeng
Superresolution imaging has revealed subcellular structures and protein interactions in many organisms. However, superresolution microscopy with lateral resolution better than 100 nm has not been achieved in photosynthetic cells due to the interference of a high-autofluorescence background. Here, we developed a photobleaching method to effectively reduce the autofluorescence of cyanobacterial and plant cells. We achieved lateral resolution of ~10 nm with stochastic optical reconstruction microscopy (STORM) in the sphere-shaped cyanobacterium Prochlorococcus and the flowering plant Arabidopsis thaliana During the cell cycle of Prochlorococcus, we characterized the three-dimensional (3D) organization of the cell division protein FtsZ, which forms a ring structure at the division site and is important for cytokinesis of bacteria and chloroplasts...
November 21, 2017: MBio
https://www.readbyqxmd.com/read/29162242/current-concepts-in-spondylopelvic-dissociation
#10
REVIEW
André Luiz Loyelo Barcellos, Vinícius M da Rocha, João Antonio Matheus Guimarães
INTRODUCTION: Spondylopelvic dissociation is an uncommon and complex injury that results from high-energy trauma with axial overloading through the sacrum. Due to the life-threatening nature of these injuries, standard Advanced Trauma Life Support® (ATLS) protocol must be used in the trauma setting as part of the initial management of these patients. The key to diagnosis is a good physical exam coupled with high level of suspicion. Radicular neurological deficits commonly are present in spondylopelvic dissociation (L5's roots) and should be documented for future evaluations...
November 2017: Injury
https://www.readbyqxmd.com/read/29156591/plasmonic-spectral-splitting-in-ring-rod-metasurface
#11
Naseer Muhammad, Adnan Daud Khan, Zi-Lan Deng, Karim Khan, Ashish Yadav, Qiang Liu, Zhengbiao Ouyang
We report spectral splitting behaviors based on Fano resonances in a novel simple planar metasurface composed of gold nanobars and nanorings. Multiple plasmonic modes and sharp Fano effects are achieved in a broadband transmittance spectrum by exploiting the rotational symmetry of the metasurface. The transmission properties are effectively modified and tuned by modulating the structural parameters. The highest single side Q-factor and FoM which reaches 196 and 105 are observed at Fano resonances. Our proposed design is relatively simple and can be applied for various applications such as multi-wavelength highly sensitive plasmonic sensors, switching, and slow light devices...
November 19, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29155710/dna-nanotubes-as-a-versatile-tool-to-study-semiflexible-polymers
#12
Jörg Schnauß, Martin Glaser, Jessica S Lorenz, Carsten Schuldt, Christin Möser, Martin Sajfutdinow, Tina Händler, Josef A Käs, David M Smith
Mechanical properties of complex, polymer-based soft matter, such as cells or biopolymer networks, can be understood in neither the classical frame of flexible polymers nor of rigid rods. Underlying filaments remain outstretched due to their non-vanishing backbone stiffness, which is quantified via the persistence length (lp), but they are also subject to strong thermal fluctuations. Their finite bending stiffness leads to unique, non-trivial collective mechanics of bulk networks, enabling the formation of stable scaffolds at low volume fractions while providing large mesh sizes...
October 25, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29150593/rapid-and-efficient-crispr-cas9-based-mating-type-switching-of-saccharomyces-cerevisiae
#13
Ze-Xiong Xie, Leslie A Mitchell, Hui-Min Liu, Bing-Zhi Li, Duo Liu, Neta Agmon, Yi Wu, Xia Li, Xiao Zhou, Bo Li, Wen-Hai Xiao, Ming-Zhu Ding, Ying Wang, Ying-Jin Yuan, Jef D Boeke
Rapid and highly efficient mating-type switching of Saccharomyces cerevisiae enables a wide variety of genetic manipulations such as the construction of strains, for instance isogenic haploid pairs of both mating-types, diploids and polyploids. We used the CRISPR/Cas9 system to generate a double-strand break (DSB) at the MAT locus, and in a single co-transformation, both haploid and diploid cells were switched to the specified mating-type at ~80% efficiency. The mating-type of strains carrying either rod or ring chromosome III were switched, including those lacking HMLα and HMRa cryptic mating loci...
November 17, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29148119/the-anatomy-of-the-pediatric-airway-has-our-knowledge-changed-in-120-years-a-review-of-historic-and-recent-investigations-of-the-anatomy-of-the-pediatric-larynx
#14
REVIEW
Josef Holzki, Karen A Brown, Robert G Carroll, Charles J Coté
BACKGROUND: There is disagreement regarding the anatomy of the pediatric airway, particularly regarding the shape of the cricoid cartilage and the location of the narrowest portion of the larynx. AIMS: The aim of this review is to clarify the origin and the science behind these differing views. METHODS: We undertook a review of published literature, University Libraries, and authoritative textbooks with key search words and phrases. RESULTS: In vivo observations suggest that the narrowest portion of the airway is more proximal than the cricoid cartilage...
November 17, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29099187/influence-of-chain-length-on-the-self-assembly-of-poly-%C3%AE%C2%B5-caprolactone-grafted-graphene-quantum-dots
#15
Nabasmita Maity, Priyadarshi Chakraborty, Arun K Nandi
The multifarious applications of graphene quantum dots (GQDs) necessitate surface modifications to enhance their solution processability. Herein, we report the synthesis and self-assembly of GQDs grafted with poly(ε-caprolactone) (PCL) of different degrees of polymerization (3, 7, 15, and 21) produced from ring-opening polymerization. Optical and morphological studies unveil the transformation of the assemblies from J-aggregates to H-aggregates, accompanied by an alteration in morphology from toroid to spheroid to rodlike structures with increasing chain length of PCL...
November 9, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28973904/molecular-architecture-of-the-sheathed-polar-flagellum-in-vibrio-alginolyticus
#16
Shiwei Zhu, Tatsuro Nishikino, Bo Hu, Seiji Kojima, Michio Homma, Jun Liu
Vibrio species are Gram-negative rod-shaped bacteria that are ubiquitous and often highly motile in aqueous environments. Vibrio swimming motility is driven by a polar flagellum covered with a membranous sheath, but this sheathed flagellum is not well understood at the molecular level because of limited structural information. Here, we use Vibrio alginolyticus as a model system to study the sheathed flagellum in intact cells by combining cryoelectron tomography (cryo-ET) and subtomogram analysis with a genetic approach...
October 10, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28964921/percutaneous-posterior-fixation-for-unstable-pelvic-ring-fractures
#17
C Tempelaere, C Vincent, C Court
INTRODUCTION: Several posterior fixation techniques for unstable pelvic ring fractures have been described. Here we present a minimally invasive, percutaneous technique to fix the two posterior iliac crests using spinal instrumentation. MATERIAL AND METHODS: Between September 2008 and March 2012, 11 patients with a mean age of 36.4 years were operated because of a vertically unstable Tile C pelvic ring fracture. Posterior fixation was performed using two polyaxial screws in each iliac crest with two subfascial connector rods...
September 27, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28963935/sustained-molecular-oxygen-activation-by-solid-iron-doped-silicon-carbide-under-microwave-irradiation-mechanism-and-application-to-norfloxacin-degradation
#18
Hongbo Li, Jing Chen, Huijie Hou, Hong Pan, Xiaoxue Ma, Jiakuan Yang, Linling Wang, John C Crittenden
Sustained molecular oxygen activation by iron doped silicon carbide (Fe/SiC) was investigated under microwave (MW) irradiation. The catalytic performance of Fe/SiC for norfloxacin (NOR) degradation was also studied. Rapid mineralization in neutral solution was observed with a pseudo-first-order rate constant of 0.2239 min(-1) under 540 W of MW irradiation for 20 min. Increasing Fe/SiC rod and MW power significantly enhanced the degradation and mineralization rate with higher yield of reactive oxygen species (ROS)...
December 1, 2017: Water Research
https://www.readbyqxmd.com/read/28961434/photoisomerization-induced-scission-of-rod-like-micelles-unravelled-with-multiscale-modeling
#19
Gabriel Heerdt, Ionut Tranca, Albert J Markvoort, Bartłomiej M Szyja, Nelson H Morgon, Emiel J M Hensen
HYPOTHESIS: In photorheological fluids, subtle molecular changes caused by light lead to abrupt macroscopic alterations. Upon UV irradiation of an aqueous cetyltrimethylammonium bromide (CTAB) and trans-ortho-methoxycinnamic acid (trans-OMCA) solution, for instance, the viscosity drops over orders of magnitude. Multiscale modeling allows to elucidate the mechanisms behind these photorheological effects. EXPERIMENTS: We use time-dependent DFT calculations to study the photoisomerization, and a combination of atomistic molecular dynamics (MD) and DFT to probe the influence of both OMCA isomers on the micellar solutions...
January 15, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28959238/z-ring-structure-and-constriction-dynamics-in-e-coli
#20
Pramod Kumar, Amarjeet Yadav, Itzhak Fishov, Mario Feingold
The Z-ring plays a central role in bacterial division. It consists of FtsZ filaments, but the way these reorganize in the ring-like structure during septation remains largely unknown. Here, we measure the effective constriction dynamics of the ring. Using an oscillating optical trap, we can switch individual rod-shaped E. coli cells between horizontal and vertical orientations. In the vertical orientation, the fluorescent Z-ring image appears as a symmetric circular structure that renders itself to quantitative analysis...
2017: Frontiers in Microbiology
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