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'Therapeutic ultrasound'

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https://www.readbyqxmd.com/read/29849768/survey-of-ultrasound-practice-amongst-podiatrists-in-the-uk
#1
Heidi J Siddle, Aimie Patience, James Coughtrey, Jean Mooney, Martin Fox, Lindsey Cherry
Background: Ultrasound in podiatry practice encompasses musculoskeletal ultrasound imaging, vascular hand-held Doppler ultrasound and therapeutic ultrasound. Sonography practice is not regulated by the Health and Care Professions Council (HCPC), with no requirement to hold a formal qualification. The College of Podiatry does not currently define ultrasound training and competencies.This study aimed to determine the current use of ultrasound, training received and mentorship received and/or provided by podiatrists using ultrasound...
2018: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29784015/induction-of-multiple-myeloma-cancer-stem-cell-apoptosis-using-conjugated-anti-abcg2-antibody-with-epirubicin-loaded-microbubbles
#2
Fangfang Shi, Miao Li, Jing Wang, Di Wu, Meng Pan, Mei Guo, Jun Dou
BACKGROUND: Multiple myeloma (MM) currently remains largely incurable. Cancer stem cells (CSCs) are believed to be responsible for drug resistance and eventual relapse. In this study, we exploited a novel agent to evaluate its inhibitory effect on MM CSCs. METHODS: Epirubicin (EPI)-loaded lipid microbubbles (MBs) conjugated with anti-ABCG2 monoclonal antibody (EPI-MBs + mAb) were developed and their effect on MM 138- CD34- CSCs isolated from human MM RPMI 8226 cell line plus ultrasound exposure in vitro and in vivo in a nonobese diabetic/severe combined immunodeficient mouse model were assessed...
May 21, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29767650/immediate-effect-of-continuous-ultrasound-vs-sham-ultrasound-for-bilateral-masseter-myalgia-a-double-blinded-trial
#3
Haseeb Hussain, Heidi Crow, Yoly Gonzalez, W D McCall
AIMS: To investigate the local and segmental effects of therapeutic ultrasound at a dose of 0.4 w/cm2 with 100% duty cycle for 5 minutes compared to the effect of sham ultrasound on painful masticatory muscles. METHODS: A total of 20 adult female subjects with bilateral masseter myalgia diagnosed according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) were included. Each subject was randomized to either an active ultrasound group or a sham ultrasound group...
May 15, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29759425/simultaneous-evaluation-of-thermal-and-non-thermal-effects-of-high-intensity-focused-ultrasound-on-a-tissue-mimicking-phantom
#4
Yong Tae Kim, Donghee Ma, Jai Kyoung Sim, Se-Hwa Kim
Physiologically relevant phantoms with high reliability are essential for extending the therapeutic applications of high-intensity therapeutic ultrasound. Here we describe a tissue-mimicking phantom capable of quantifying temperature changes and observing non-thermal phenomena by high-intensity therapeutic ultrasound. Using polydiacetylene liposomes, we fabricated agar-based polydiacetylene hydrogel phantoms (PHPs) that not only respond to temperature, but also have acoustic properties similar to those of human liver tissue...
May 11, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29721100/establishing-sheep-as-an-experimental-species-to-validate-ultrasound-mediated-blood-brain-barrier-opening-for-potential-therapeutic-interventions
#5
Matthew Pelekanos, Gerhard Leinenga, Mostafa Odabaee, Maryam Odabaee, Siamak Saifzadeh, Roland Steck, Jürgen Götz
Rationale: Treating diseases of the brain such as Alzheimer's disease (AD) is challenging as the blood-brain barrier (BBB) effectively restricts access of a large number of potentially useful drugs. A potential solution to this problem is presented by therapeutic ultrasound, a novel treatment modality that can achieve transient BBB opening in species including rodents, facilitated by biologically inert microbubbles that are routinely used in a clinical setting for contrast enhancement. However, in translating rodent studies to the human brain, the presence of a thick cancellous skull that both absorbs and distorts ultrasound presents a challenge...
2018: Theranostics
https://www.readbyqxmd.com/read/29705468/the-short-term-effects-of-tens-plus-therapeutic-ultrasound-combinations-in-chronic-neck-pain
#6
Selcuk Sayilir
INTRODUCTION: To investigate the effects of TENS plus therapeutic ultrasound combinations on symptom relief, physical functionality, perceived stress levels, daytime sleepiness and neck mobility in patients with chronic neck pain (CNP). METHODS: A total of 64 patients were divided into two groups as the TENS plus ultrasound group (n = 39) and the control CNP group (n = 25). The therapy comprised TENS and therapeutic ultrasound applications for 10 sessions...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29613883/long-term-course-of-shoulders-after-ultrasound-therapy-for-calcific-tendinitis-results-of-the-ten-years-follow-up-of-an-rct
#7
Karin Pieber, Martina Grim-Stieger, Franz Kainberger, Martin Funovics, Karl-Ludwig Resch, Thomas Bochdansky, Eleonore Pablik, Gerold Ebenbichler
OBJECTIVE: To follow both the structure and function related long-term course of shoulders that had been treated with therapeutic ultrasound (US) for symptomatic calcific tendinitis. DESIGN: Long-term follow-up of 45 shoulders (37 patients) that had been treated for symptomatic calcific tendinitis with either a series of US or sham US ten years ago. The main outcome variables were presence of calcium deposits and subacromial impingement on standardized X-ray imaging, shoulder symptoms (Binder score) and function (Constant score)...
April 2, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29560717/heating-induced-by-therapeutic-ultrasound-in-the-presence-of-magnetic-nanoparticles
#8
Katarzyna Kaczmarek, Tomasz Hornowski, Martina Kubovčíková, Milan Timko, Marceli Koralewski, Arkadiusz Józefczak
The efficiency of ultrasound hyperthermia for anti-cancer treatments such as radiotherapy or chemotherapy can be improved by using sonosensitizers, which are materials that enhance the attenuation and dissipation of acoustic energy. We propose the use of magnetic nanoparticles as sonosensitizers because of their biocompatibility, nontoxicity, and common use in several medical applications. A magnetic material was synthetized and then incorporated in the form of a magnetic fluid in agar tissue-mimicking phantoms...
April 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29553049/the-influence-of-medium-elasticity-on-the-prediction-of-histotripsy-induced-bubble-expansion-and-erythrocyte-viability
#9
Kenneth B Bader
Histotripsy is a form of therapeutic ultrasound that liquefies tissue mechanically via acoustic cavitation. Bubble expansion is paramount in the efficacy of histotripsy therapy, and the cavitation dynamics are strongly influenced by the medium elasticity. In this study, an analytic model to predict histotripsy-induced bubble expansion in a fluid was extended to include the effects of medium elasticity. Good agreement was observed between the predictions of the analytic model and numerical computations utilizing highly nonlinear excitations (shock-scattering histotripsy) and purely tensile pulses (microtripsy)...
May 2, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29496981/advanced-ultrasound-technologies-for-diagnosis-and-therapy
#10
Anne Rix, Wiltrud Lederle, Benjamin Theek, Twan Lammers, Chrit Moonen, Georg Schmitz, Fabian Kiessling
Ultrasound is among the most rapidly advancing imaging techniques. Functional methods such as elastography have been clinically introduced, and tissue characterization is improved by contrast-enhanced scans. Here, novel superresolution techniques provide unique morphologic and functional insights into tissue vascularization. Functional analyses are complemented by molecular ultrasound imaging, to visualize markers of inflammation and angiogenesis. The full potential of diagnostic ultrasound may become apparent by integrating these multiple imaging features in radiomics approaches...
May 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29451124/copper-oxide-loaded-plga-nanospheres-towards-a-multifunctional-nanoscale-platform-for-ultrasound-based-imaging-and-therapy
#11
Or Perlman, Iris S Weitz, Sarit S Sivan, Hiba Abu-Khalla, Madeleine Benguigui, Yuval Shaked, Haim Azhari
Copper oxide nanoparticles (CuO-NPs) are increasingly becoming the subject of investigation exploring their potential use for diagnostic and therapeutic purposes. Recent work has demonstrated their anticancer potential, as well as contrast agent capabilities for magnetic resonance imaging (MRI) and through-transmission ultrasound. However, no capability of CuO-NPs has been demonstrated using conventional ultrasound systems, which, unlike the former, are widely deployed in the clinic. Furthermore, in spite of their potential as multifunctional nano-based materials for diagnosis and therapy, CuO-NPs have been delayed from further clinical application due to their inherent toxicity...
May 4, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29406415/magnetic-resonance-imaging-guided-high-intensity-focused-ultrasound-applications-in-pediatrics-early-experience-at-children-s-national-medical-center
#12
Karun V Sharma, Pavel S Yarmolenko, Avinash Eranki, Ari Partanen, Haydar Celik, AeRang Kim, Matthew Oetgen, Peter C W Kim
Magnetic resonance imaging-guided high-intensity focused ultrasound (MR-HIFU) is a novel technology that integrates magnetic resonance imaging with therapeutic ultrasound. This unique approach provides a completely noninvasive method for precise thermal ablation of targeted tissues with real-time imaging feedback. Over the past 2 decades, MR-HIFU has shown clinical success in several adult applications ranging from treatment of painful bone metastases to uterine fibroids to prostate cancer and essential tremor...
February 2018: Topics in Magnetic Resonance Imaging: TMRI
https://www.readbyqxmd.com/read/29389657/diffraction-effects-and-compensation-in-passive-acoustic-mapping
#13
Michael D Gray, Erasmia Lyka, Constantin C Coussios
Over the last decade, a variety of noninvasive techniques have been developed to monitor therapeutic ultrasound procedures in support of safety or efficacy assessments. One class of methods employs diagnostic ultrasound arrays to sense acoustic emissions, thereby providing a means to passively detect, localize, and quantify the strength of nonlinear sources, including cavitation. Real array element diffraction patterns may differ substantially from those presumed in existing beamforming algorithms. However, diffraction compensation has received limited treatment in passive and active imaging, and measured diffraction data have yet to be used for array response correction...
February 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29373113/comparison-of-the-effects-of-1mhz-and-3mhz-therapeutic-ultrasound-on-endothelium-dependent-vasodilation-of-humans-a-randomised-clinical-trial
#14
M Hauck, C Noronha Martins, M Borges Moraes, P Aikawa, F da Silva Paulitsch, R Della Méa Plentz, S Teixeira da Costa, A M Vargas da Silva, L U Signori
OBJECTIVE: To compare the effects of different waveforms of 1MHz and 3MHz therapeutic ultrasound on endothelial function in healthy subjects. DESIGN: Randomised placebo-controlled, crossover study with concealed allocation and assessor blinding. SETTING: Imaging Centre of the University Hospital. PARTICIPANTS: Thirty volunteers aged between 18 and 35 years were divided into two homogeneous groups (1MHz and 3MHz). INTERVENTIONS: Continuous (CUT; 0...
December 5, 2017: Physiotherapy
https://www.readbyqxmd.com/read/29346155/diagnostic-and-therapeutic-ultrasound-on-venous-and-arterial-ulcers-a-focused-review
#15
(no author information available yet)
No abstract text is available yet for this article.
February 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29346145/diagnostic-and-therapeutic-ultrasound-on-venous-and-arterial-ulcers-a-focused-review
#16
Steven J Kavros, Robert Coronado
GENERAL PURPOSE: To provide information about the use of ultrasound for diagnostic and therapeutic treatment of venous and arterial ulcers. TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After completing this continuing education activity, you should be able to: ABSTRACT: To review the diagnostic and therapeutic use of ultrasound on venous and arterial ulcers...
February 2018: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/29318418/investigation-of-the-effectiveness-of-therapeutic-ultrasound-with-high-resolution-ultrasonographic-cross-sectional-area-measurement-of-cervical-nerve-roots-in-patients-with-chronic-cervical-radiculopathy-a-prospective-controlled-single-blind-study
#17
Burcu Metin Ökmen, Korgün Ökmen, Lale Altan
PURPOSE: The purpose of our study was to evaluate the effects of therapeutic ultrasound (US) on chronic cervical radiculopathy (CR) patients using both the clinical parameters and the cross-sectional area (CSA) values of the cervical nerve roots (NR) measured by high-resolution ultrasonography (HRUS). METHODS: Thirty-two patients with chronic CR were included in this prospective, controlled, and single-blind study. All of the patients received therapeutic US at continuous mode, 1-MHz frequency, and 1...
January 9, 2018: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29278606/local-application-of-ultrasound-attenuates-neuropathic-allodynia-and-proinflammatory-cytokines-in-rats-after-thoracotomy
#18
Ching-Hsia Hung, Chong-Chi Chiu, Chen-Chih Liu, Yu-Wen Chen
BACKGROUND AND OBJECTIVES: We aimed to investigate the effect of therapeutic ultrasound (TU) on pain sensitivity and the concentration inflammatory cytokines in a thoracotomy rat model. METHODS: Rats were distributed randomly into 4 groups: (1) sham operated, (2) thoracotomy and rib retraction (TRR), (3) TRR rats that received TU (TRR + TU-1), and (4) TRR rats that received TU with the ultrasound turned off (TRR + TU-0). Ultrasound was set at 1-MHz frequency (1...
February 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29205374/ethyl-chloride-spray-for-musculoskeletal-ultrasound-guided-injections-an-alternative-to-subcutaneous-injection-of-local-anesthetic-solution
#19
Amit Shah, Alessandro Vidoni, Sharon McGarry, Mark Davies, Steven James, Rajesh Botchu
Ultrasound-guided injections such as steroid injections are common procedures involving the musculoskeletal system. They are usually performed after a subcutaneous injection of local anesthetic (LA), which can be painful. In 126 consecutive patients, local anesthesia was performed using ethyl chloride spray prior to a therapeutic ultrasound-guided injection in joints, tendons, or bursae. Ninety-nine (78.5%) patients found the use of ethyl chloride spray helpful. The use of ethyl chloride spray is an effective, patient-friendly alternative to the standard injection of local aesthetic for ultrasound-guided therapeutic musculoskeletal injections with the advantage of a lower cost of $0...
February 2018: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29195473/clustering-dynamics-of-microbubbles-exposed-to-low-pressure-1-mhz-ultrasound
#20
Carole Lazarus, Antonios N Pouliopoulos, Marc Tinguely, Valeria Garbin, James J Choi
Ultrasound-driven microbubbles have been used in therapeutic applications to deliver drugs across capillaries and into cells or to dissolve blood clots. Yet the performance and safety of these applications have been difficult to control. Microbubbles exposed to ultrasound not only volumetrically oscillate, but also move due to acoustic radiation, or Bjerknes, forces. The purpose of this work was to understand the extent to which microbubbles moved and clustered due to secondary Bjerknes forces. A microbubble population was exposed to a 1-MHz ultrasound pulse with a peak-rarefactional pressure of 50-100 kPa and a pulse length of 20 ms...
November 2017: Journal of the Acoustical Society of America
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