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Subgemmal neurogenous plaque

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https://www.readbyqxmd.com/read/28488063/subgemmal-neurogenous-plaque-of-the-tongue-a-report-of-three-cases
#1
Amanda Katarinny Goes Gonzaga, Deborah Gondim Lambert Moreira, Dáurea Adília Cóbe Sena, Maria Luiza Diniz de Sousa Lopes, Lélia Batista de Souza, Lélia Maria Guedes Queiroz
Subgemmal neurogenous plaque (SNP) is a biphasic neural structure associated with the taste buds. Clinically, SNP usually presents as an asymptomatic, normally colored, papule located in the posterior lateral border of the tongue. Accurate diagnosis is based only on histopathological examination, which shows a superficial neurofibroma-like pattern and a neuroma-like in the deep zone. Appropriate recognition of clinical and morphological aspects of SNPs can avoid their misdiagnosis as neural neoplasms. We report three cases of SNP with detailed clinical, histopathological, and immunohistochemical features...
May 10, 2017: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28229898/histomorphometric-characterization-of-subgemmal-neurogenous-plaques
#2
Ana Carolina Amorim Pellicioli, Felipe Paiva Fonseca, Rodrigo Neves Silva, Luiz Alcino Monteiro Gueiros, Oslei Paes de Almeida, Pablo Agustin Vargas, Marcio Ajudarte Lopes, Helder Antonio Rebelo Pontes, Manoela Domingues Martins, Vinícius Coelho Carrard, Alan Roger Santos-Silva
OBJECTIVES: The aim of this study was to characterize the histomorphometric features of subgemmal neurogenous plaques (SNPs) to better understand their relationship to surrounding microanatomy included in the tissue biopsy samples of the tongue. STUDY DESIGN: A 12-year retrospective study on the files of 3 oral pathology centers yielded 28 SNPs. Hematoxylin and eosin-stained sections were used for histologic analysis, and immunohistochemical staining for S100 protein was performed to better characterize the neural structures...
January 9, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/19913727/subgemmal-neurogenous-plaque-clinical-and-microscopic-evaluation-of-7-cases
#3
Luiz Alcino Gueiros, Jorge Esquiche León, Jair Carneiro Leão, Márcio Ajudarte Lopes, Jacks Jorge, Oslei Paes de Almeida
Subgemmal neurogenous plaques (SNPs) are biphasic neural structures found on the posterolateral border of the tongue. Fewer than 40 cases have been reported and only a few were symptomatic. The present report details the features of 7 cases of SNP retrieved from the files of a single institution. Clinical and histopathological data were reviewed and immunohistochemical analysis was performed for S100, CD56, neuron-specific enolase, epithelial membrane antigen, CK7, CK8, CK14, and CK20. All cases showed similar morphological and immunohistochemical characteristics...
December 2009: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
https://www.readbyqxmd.com/read/18372161/subgemmal-neurogenous-plaque-associated-with-burning-tongue-report-of-two-cases-and-review-of-the-literature
#4
REVIEW
L A Gueiros, J E Leon, M A Lopes, O P de Almeida, J Jorge
Subgemmal neurogenous plaques, biphasic structures with a neurofibroma and neuroma patterns, are observed in tongue biopsies involving subepithelial areas, being characterized as aggregates of nerve plexus and ganglion cells. Oral burning symptoms, having many possible causes, are commonly observed during oral medicine practice, but the association of subgemmal neurogenous plaque with tongue burning symptoms is very unusual. Reported here are two cases of focal burning sensation in the lateral border of the tongue diagnosed as subgemmal neurogenous plaque through biopsy...
August 2008: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/16872442/lingual-subgemmal-neurogenous-plaques-with-pseudoepitheliomatous-hyperplasia-incidental-pseudomalignant-condition
#5
J Fernando Val-Bernal, Isidro Rivadulla, M Francisca Garijo
Pseudoepitheliomatous hyperplasia is a reactive proliferation of benign squamous epithelium that can mimic squamous cell carcinoma. Herein is a report on this type of reaction on two subgemmal neurogenous plaques in a lingual circumvallate papilla. To the authors' knowledge this is the first report on this combination of lesions. A 66-year-old man died with disseminated squamous cell carcinoma of the lung. At autopsy the tongue was found to have an incidental pseudoepitheliomatous hyperplasia on two subgemmal neurogenous plaques with ganglion cells...
August 2006: Pathology International
https://www.readbyqxmd.com/read/15297966/structural-organization-of-subgemmal-neurogenous-plaques-in-foliate-papillae-of-tongue
#6
Asterios Triantafyllou, Philip Coulter
Little is known about subgemmal neurogenous plaques in the foliate papillae of tongue, which prompted the present investigation. The plaques were immunohistochemically studied in biopsies from 16 adults with the use of neural, stromal, basement membrane, and cell-cycle markers. They displayed a zonal pattern of organization. The neurofibroma-like superficial zone expanded lamina propria and was contiguous to the epithelium covering the papillae. It consisted of tangled composites of S-100 protein-positive spindled cells and fibrils stained for protein gene product 9...
August 2004: Human Pathology
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