David H Au, Emily Gleason, Rachel Hunter-Merrill, Anna E Barón, Margaret Collins, Corina Ronneberg, Nan Lv, Peter Rise, Travis Hee Wai, Robert Plumley, Stephen R Wisniewski, Frank Sciurba, Dong-Yun Kim, Paul Simonelli, Jerry A Krishnan, Christine H Wendt, Laura C Feemster, Gerard J Criner, Veeranna Maddipati, Arjun Mohan, Jun Ma
Rationale Being overweight or obese is common among patients with chronic obstructive pulmonary disease (COPD), but whether interventions targeted at weight loss improve functional impairments is unknown. Objectives INSIGHT tested whether a pragmatic low-intensity lifestyle intervention would lead to better physical functional status among participants with overweight or obesity and COPD. Methods The trial was a 12-month, multicentered, patient-level pragmatic clinical trial. Participants were recruited from April 2017 to August 2019 from 38 sites across the U...
September 28, 2023: Annals of the American Thoracic Society