Satu J Lehtola, Jetro J Tuulari, Noora M Scheinin, Linnea Karlsson, Riitta Parkkola, Harri Merisaari, John D Lewis, Vladimir S Fonov, D Louis Collins, Alan Evans, Jani Saunavaara, Niloofar Hashempour, Tuire Lähdesmäki, Henriette Acosta, Hasse Karlsson
Maternal psychological distress during pregnancy (PPD)1 has been associated with changes in offspring amygdalar and hippocampal volumes. Studies on child amygdalae suggest that sex moderates the vulnerability of fetal brains to prenatal stress. However, this has not yet been observed in these structures in newborns. Newborn studies are crucial, as they minimize the confounding influence of postnatal life. We investigated the effects of maternal prenatal psychological symptoms on newborn amygdalar and hippocampal volumes and their interactions with newborn sex in 123 newborns aged 2-5 weeks (69 males, 54 females)...
2020: NeuroImage: Clinical