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complications of respiratory distress syndrome

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https://www.readbyqxmd.com/read/30431163/rescue-therapy-for-hypercapnia-due-to-high-peep-mechanical-ventilation-in-patients-with-ards-and-renal-failure
#1
April A Grant, Valerie J Hart, Edward B Lineen, Brian C Forsberg, Alan Klima, Mehdi Mirsaeidi, Ivonne H Schulman, Amit Badiye, Rodrigo M Vianna, Amit Patel, Matthias Loebe, Ali Ghodsizad
Extracorporeal removal of carbon dioxide in patients experiencing severe hypercapnia due to lung protective mechanical ventilation was first described over four decades ago. There have been many devices developed and described in the interim, many of which require additional training, resources and staff. This manuscript describes a readily available and relatively simple adjunct that can provide partial lung support in patients with acute respiratory distress syndrome complicated by severe hypercapnia and acute kidney injury requiring dialysis...
November 15, 2018: Artificial Organs
https://www.readbyqxmd.com/read/30429690/poractant-alfa-versus-beractant-for-neonatal-respiratory-distress-syndrome-a-retrospective-cost-analysis
#2
Sara Brown, Jeff Hurren, Heidi Sartori
OBJECTIVES: The objectives of this study were to determine the average medication cost per patient of poractant alfa and beractant, and to compare the outcomes of treatment with these agents. METHODS: We conducted a retrospective, observational, cohort study of patients who received surfactant, before and after an institutional formulary change from beractant to poractant alfa. The primary outcome was the average medication cost per case. Secondary measures were clinical outcomes, including duration of respiratory support, length of hospital stay, and the occurrence of complications...
September 2018: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/30429074/effectiveness-of-ecmo-for-burn-related-acute-respiratory-distress-syndrome
#3
R Scott Eldredge, Yan Zhai, Amalia Cochran
INTRODUCTION: Acute respiratory distress syndrome (ARDS) is a complication that affects approximately 40% of burn patients and is associated with high mortality rates. Extracorporeal membrane oxygenation (ECMO) therapy is a management option for severe refractory hypoxemic respiratory failure; however, there is little literature reporting the effectiveness of this therapy in burns. Our study objective was to review patient outcomes in burns following severe ARDS treated with ECMO. METHODS: We retrospectively reviewed all patients treated with ECMO for ARDS who received their burn care at a single regional burn center between 9/1/2006 and 8/31/2016...
November 11, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/30428928/is-goal-directed-fluid-therapy-based-on-dynamic-variables-alone-sufficient-to-improve-clinical-outcomes-among-patients-undergoing-surgery-a-meta-analysis
#4
Qi-Wen Deng, Wen-Cheng Tan, Bing-Cheng Zhao, Shi-Hong Wen, Jian-Tong Shen, Miao Xu
BACKGROUND: Whether goal-directed fluid therapy based on dynamic predictors of fluid responsiveness (GDFTdyn) alone improves clinical outcomes in comparison with standard fluid therapy among patients undergoing surgery remains unclear. METHODS: PubMed, EMBASE, the Cochrane Library and ClinicalTrials.gov were searched for relevant studies. Studies comparing the effects of GDFTdyn with that of standard fluid therapy on clinical outcomes among adult patients undergoing surgery were considered eligible...
November 14, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/30424584/diabetes-in-pregnancy-and-micrornas-promises-and-limitations-in-their-clinical-application
#5
REVIEW
Adriana Ibarra, Begoña Vega-Guedes, Yeray Brito-Casillas, Ana M Wägner
Maternal diabetes is associated with an increased risk of complications for the mother and her offspring. The latter have an increased risk of foetal macrosomia, hypoglycaemia, respiratory distress syndrome, preterm delivery, malformations and mortality but also of life-long development of obesity and diabetes. Epigenetics have been proposed as an explanation for this long-term risk, and microRNAs (miRNAs) may play a role, both in short- and long-term outcomes. Gestation is associated with increasing maternal insulin resistance, as well as β-cell expansion, to account for the increased insulin needs and studies performed in pregnant rats support a role of miRNAs in this expansion...
November 12, 2018: Non-Coding RNA
https://www.readbyqxmd.com/read/30422928/envenomation-by-the-common-european-adder-vipera-berus-a-case-series-of-219-patients
#6
Mette N Hermansen, Andrea H Krug, Eirik Tjønnfjord, Mikkel Brabrand
OBJECTIVES: Every year, several patients are bitten by the common European adder (Vipera berus). The aim of this study is to present a large consecutive case series of patients bitten by V. berus, and to identify signs and symptoms indicative of complicated illness. PATIENTS AND METHODS: This is a retrospective case series from the Hospital of South West Jutland, Denmark. All 219 patients bitten by V. berus (diagnosed by history or clinical findings) from 1994 to 2012 were identified through hospital databases...
November 12, 2018: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/30419501/current-evidence-on-%C3%AF-3-fatty-acids-in-enteral-nutrition-in-the-critically-ill-a-systematic-review-and-meta-analysis
#7
REVIEW
Wac Kristine Koekkoek, Vasilianna Panteleon, Arthur Rh van Zanten
Fish oil exerts anti-inflammatory and immunomodulatory properties that may be beneficial for critically ill patients, thus multiple randomized controlled trials and meta-analyses have been performed. However, controversy remains as to whether fish oil-enriched enteral nutrition can improve clinical outcomes in adult critically ill patients in intensive care units (ICUs). The aim of this study was to provide an up-to-date systematic review and meta-analysis of all randomized controlled trials of fish oil-containing enteral nutrition addressing relevant clinical outcomes in critically ill patients...
July 31, 2018: Nutrition
https://www.readbyqxmd.com/read/30417214/treatment-of-a-broncho-esophageal-fistula-complicated-by-severe-ards
#8
E Tautz, D Wagner, S Wiesemann, A Jonaszik, C Bode, T Wengenmayer, D Staudacher, P Biever, J Hoeppner, D Duerschmied
INTRODUCTION: Broncho-esophageal fistula formation is a rare complication of tuberculosis, most often seen in immunocompromised patients. METHODS AND RESULTS: In this paper, we report the case of a young non-immunocompromised refugee from Somalia diagnosed with open pulmonary tuberculosis complicated by extensive osseous involvement and a broncho-esophageal fistula with consecutive aspiration of gastric contents. The patient rapidly developed a severe acute respiratory distress syndrome (ARDS) requiring venovenous extracorporeal membrane oxygenation (ECMO) therapy for nearly 2 months...
November 11, 2018: Infection
https://www.readbyqxmd.com/read/30405282/clinical-and-laboratory-features-associated-with-acute-kidney-injury-in-severe-malaria
#9
Hiren Anghan, Prayas Sethi, Manish Soneja, Sandeep Mahajan, Naveet Wig
Introduction: Critically ill severe malaria constitutes one of the major hospital admissions in Indian setting. Clinical studies identifying the factors associated with acute kidney injury (AKI) in malaria are lacking. This study aimed to identify these factors. Methods: This prospective observational study was conducted in a tertiary care center of North India. All adult patients with severe malaria were studied during 2012-2014. Results: The study included 79 patients and AKI was observed in 36 patients...
October 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/30402491/a-retrospective-study-on-the-risk-of-respiratory-distress-syndrome-in-singleton-pregnancies-with-preterm-premature-rupture-of-membranes-between-24-0-and-36-6-weeks-using-regression-analysis-for-various-factors
#10
Anna Niesłuchowska-Hoxha, Wojciech Cnota, Bartosz Czuba, Aleksandra Ruci, Magdalena Ciaciura-Jarno, Agnieszka Jagielska, Dominik Wójtowicz, Rafał Kierach, Krzysztof Dąbrowski, Marcin Sidorowicz, Wioletta Skrzypulec-Plinta, Agata Wloch, Dariusz Borowski, Piotr Węgrzyn
Aim: This study aimed to investigate the cause of respiratory distress syndrome (RDS) in neonates from singleton pregnancies with preterm premature rupture of membranes (pPROM) between 24+0 and 36+6 weeks by using regression analysis for various factors. Methods: In 175 singleton pregnancies with pPROM, 95 cases of RDS (54,29%) were diagnosed. In all cases the following information was collected: latency period of PROM, gestational age at birth, Umbilical Artery Pulsatility Index (UA PI), Middle Cerebral Artery Pulsatility Index (MCA PI), fetal distress, antenatal steroids use, delivery type, pregnancy hypertension disease, gestational glucose intolerance or diabetes, neonatal laboratory parameters, gender, weight, Apgar score, and other neonatal complications...
2018: BioMed Research International
https://www.readbyqxmd.com/read/30370228/respiratory-failure-in-the-hematopoietic-stem-cell-transplant-recipient
#11
REVIEW
Patrick M Wieruszewski, Svetlana Herasevich, Ognjen Gajic, Hemang Yadav
The number of patients receiving hematopoietic stem cell transplantation (HSCT) is rapidly rising worldwide. Despite substantial improvements in peri-transplant care, pulmonary complications resulting in respiratory failure remain a major contributor to morbidity and mortality in the post-transplant period, and represent a major barrier to the overall success of HSCT. Infectious complications include pneumonia due to bacteria, viruses, and fungi, and most commonly occur during neutropenia in the early post-transplant period...
October 16, 2018: World Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/30353096/clinical-characteristics-of-patients-with-laboratory-confirmed-influenza-a-h1n1-pdm09-during-the-2013-2014-and-2015-2016-clade-6b-6b-1-6b-2-predominant-outbreaks
#12
Yu-Chia Hsieh, Kuo-Chien Tsao, Ching-Tai Huang, Kuang-Yi Chang, Yhu-Chering Huang, Yu-Nong Gong
A novel pandemic influenza A(H1N1)pdm09 virus emerged in 2009 globally, and it continues to circulate in humans. The National Influenza Surveillance Network in Taiwan identified five A(H1N1)pdm09-predominant seasons, representing the 2009/2010, 2010/2011, 2012/2013, 2013/2014, and 2015/2016 outbreaks from 2009 to 2016. Independently, a retrospective cohort study (which enrolled 639 infected patients during the five seasons) was conducted at Chang Gung Memorial Hospital to explore the risk factors associated with influenza A(H1N1)pdm09-related complications...
October 23, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30345124/moderate-hypertriglyceridemia-causing-recurrent-pancreatitis-a-case-report-and-the-literature-review
#13
Vijay Gayam, Amrendra Kumar Mandal, Pavani Garlapati, Mazin Khalid, Arshpal Gill, Khalid Mowyad
Recurrent acute pancreatitis secondary to hypertriglyceridemia (HTG) with levels below 1000 mg/dL has been rarely reported in the literature. HTG is the third most common cause of acute pancreatitis and has been established in the literature as a risk factor when levels are greater than 1000 mg/dL. A 43-year-old patient presented to the hospital with severe epigastric abdominal pain. Initial laboratory investigations were significant for a lipase level of 4143 U/L and a triglyceride level of 600 mg/dL. Computed tomography (CT) of the abdomen showed diffuse enlargement of the pancreas consistent with pancreatitis...
2018: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/30344561/controlled-blood-pressure-elevation-and-limited-fluid-resuscitation-in-the-treatment-of-multiple-injuries-in-combination-with-shock
#14
Yan Lu, Liping Liu, Jing Wang, Limin Cui
Objective: To explore the effectiveness of controlled blood pressure elevation and limited fluid resuscitation in treating patients with multiple injuries in combination with shock in Intensive Care Unit (ICU). Methods: One hundred and sixty-four patients with multiple injuries in combination with shock who were admitted into the ICU of the hospital between June 2014 and November 2017 were selected and divided into an observation group and a control group using random number table, 82 each group...
September 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/30338088/preparedness-for-rapid-veno-venous-extracorporeal-membrane-oxygenation-introduction-for-pediatric-severe-acute-respiratory-distress-syndrome-a-case-report
#15
Chiaki Toida, Takashi Muguruma, Katsutaka Hashiba, Masayasu Gakumazawa, Naoto Morimura
Case: Previous research has suggested that venovenous extracorporeal membrane oxygenation (vvECMO) is useful for patients refractory to conventional therapy. We report a pediatric case of influenza A(H1N1)pdm09 infection with a good outcome following rapid initiation of vvECMO.This patient was a 13-year-old boy with severe acute respiratory distress syndrome due to influenza virus. Severe acute respiratory distress syndrome according to the Berlin definition, Murray score of 3.3, and severe air leak syndrome were found...
October 2018: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/30337650/the-emergence-of-pathogenic-tnf-inos-producing-dendritic-cells-tip-dcs-in-a-malaria-model-of-acute-respiratory-distress-syndrome-ards-is-dependent-on-ccr4
#16
Bruno Galvão-Filho, Júlia Teixeira de Castro, Maria Marta Figueiredo, Claudio Gonçalves Rosmaninho, Lis Ribeiro do Valle Antonelli, Ricardo Tostes Gazzinelli
Malaria-associated acute respiratory distress syndrome (MA-ARDS) and acute lung injury (ALI) are complications that cause lung damage and often leads to death. The MA-ARDS/ALI is associated with a Type 1 inflammatory response mediated by T lymphocytes and IFN-γ. Here, we used the Plasmodium berghei NK65 (PbN)-induced MA-ALI/ARDS model that resembles human disease and confirmed that lung CD4+ and CD8+ T cells predominantly expressed Tbet and IFN-γ. Surprisingly, we found that development of MA-ALI/ARDS was dependent on functional CCR4, known to mediate the recruitment of Th2 lymphocytes and regulatory T cells...
October 18, 2018: Mucosal Immunology
https://www.readbyqxmd.com/read/30337209/two-medullary-hemorrhage-cases-complicated-by-respiratory-distress-in-the-early-phase
#17
Ryuichiro Yagi, Yoshinori Nishimoto, Satoshi Yamada, Hanae Nakashima, Kensuke Okada, Fumie Konoeda, Haruhiko Hoshino
Medullary hemorrhage is quite rare among brain stem hemorrhage cases, thus the clinical course remains unclear. In the medulla oblongata, respiratory centers are located and previous reports indicate that medullary lesions have possible relationship with acute respiratory distress syndrome. This kind of respiratory failure is commonly caused by neurogenic pulmonary edema (NPE), which is defined as noncardiac noninfectious acute respiratory distress syndrome with changes in intracranial condition including cerebrovascular events...
October 15, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30318947/fetal-pulmonary-artery-acceleration-ejection-time-prognostic-accuracy-for-respiratory-complications-in-preterm-prelabor-rupture-of-membranes
#18
Jose R Duncan, Ana M Tobiasz, Katherine M Dorsett, Michael M Aziz, Rebecca E Thompson, Zoran Bursac, Ajay J Talati, Giancarlo Mari M D Mba, Mauro H Schenone
OBJECTIVE: To determine the prognostic accuracy of the fetal pulmonary artery acceleration time/ejection time (PATET) for the prediction of neonatal respiratory complications (NRC) in pregnancies with preterm premature rupture of membranes (PPROM). METHODS: This is a prospective cohort of singleton pregnancies complicated by PPROM managed in our institution from October 2015 to April 2018. Inclusion criteria included mothers from 13-46 years of age and singleton pregnancies with PATET measurements < 7 days prior to delivery...
October 14, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30310009/-modified-david-komeda-repair-for-ventricular-septal-perforation-complicated-with-severe-postoperative-acute-respiratory-distress-syndrome-report-of-a-case
#19
Takeshi Katsube, Satoshi Saito, Hiroyuki Tsukui, Kenji Yamazaki, Hiroshi Niinami
A 61-year-old man presented by ambulance with dyspnea. He was diagnosed with myocardial infarction complicated with ventricular septal perforation (VSP), and intraaortic balloon pumping support and intensive care were started. Because of instability of hemodynamic status, modified David-Komeda operation with double patch was performed in the subacute phase of VSP. Although he developed acute respiratory distress syndrome( ARDS) on the 21st day after operation, he was successfully treated with corticosteroid pulse therapy and artificial ventilation...
October 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/30306815/epidemiology-and-outcome-of-acute-kidney-injury-due-to-venomous-animals-from-a-subtropical-region-of-india
#20
Sanjay Vikrant, Ajay Jaryal, Dalip Gupta, Anupam Parashar
AIM: To study the epidemiology and outcome of acute kidney injury (AKI) caused by venomous animals. METHODS: A retrospective study of patients admitted at Indira Gandhi Medical College Hospital, Shimla, with AKI due to venomous animals over a period of 15 years (January 2003-December 2017). Medical records were evaluated for patient information on demographic factors, clinical characteristics, complications, and outcome. Outcomes of requirement for intensive care unit (ICU) support, treatment with dialysis, survival, and mortality were analyzed...
October 11, 2018: Clinical Toxicology
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