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complications of respiratory distress syndrome

Asım Enes Özbek, Yavuz Selim Divrikoğlu, Serkan Yılmaz, Nurcihan Ülkü Aytaş, Emrah Çelik
Drug induced acute respiratory distress syndrome (ARDS) is a common clinical condition. Patients typically present with noncardiogenic pulmonary edema. Large number of ARDS cases reported induced by antineoplastic drugs and other drug intoxications. The pathophysiologic mechanisms of drug induced ARDS remains unknown. One of the postulated mechanisms of drug induced ARDS is anaphylaxis. We present a case of acute respiratory distress syndrome complicated by anaphylactic shock after use of two different nonsteroidal antiinflammatory drugs (NSAID)...
July 3, 2018: American Journal of Emergency Medicine
Dong Tien Ngo, Phuc Huu Phan, Shoji Kawachi, Noriko Nakajima, Naoyuki Hirata, Akira Ainai, Thuy Thi Bich Phung, Dien Minh Tran, Hai Thanh Le
BACKGROUND: Tuberculous (TB) pneumonia can induce acute respiratory distress syndrome (ARDS). Although TB pneumonia is one of the causes of disease and death among children worldwide, the literature on TB pneumonia-induced ARDS is limited. We report herein on the successful treatment of a two-year-old female child with TB pneumonia-induced severe ARDS complicated with disseminated intravascular coagulation (DIC). CASE PRESENTATION: A two-year-old Vietnamese female child with sustained fever and cough for 20 days was transferred to our hospital...
July 3, 2018: BMC Infectious Diseases
Radu T Stoica, Ioan Cordoş, Anca Macri
Introduction: The Acute Respiratory Distress Syndrome (ARDS) is a severe hypoxemic acute lung injury that may complicate lung resections. Reported mortality is very high, up to 50%. This report covers an ARDS case occurring post left pneumonectomy, with a favorable outcome, despite association with an acute colonic pseudo-obstruction syndrome (Ogilvie syndrome) that required abdominal surgery for decompression. Case Report: A 60-year old Caucasian male, diagnosed with a stage IIIA left lung tumor underwent a left pneumonectomy...
January 2018: Journal of Critical Care Medicine
Haoshu Ding, Yan Wang, Wenwen Dong, Rongrong Ren, Yanfei Mao, Xiaoming Deng
Ventilator-induced lung injury (VILI) has implications for mortality from acute lung injury (ALI) and for acute respiratory distress syndrome (ARDS) patients; the complicated mechanisms of VILI have not been well defined. To discover new biomarkers and mechanisms of VILI, isobaric Tag for Relative and Absolute Quantitation (iTRAQ)-based quantitative proteomics were applied to identify differentially expressed proteins in mice treated with high tidal volume ventilation (HV), low tidal volume ventilation (LV) and lipopolysaccharide (LPS)...
2018: Chemical & Pharmaceutical Bulletin
Winnie Huiyan Sim, Hamon Ng, Penelope Sheehan
PURPOSE: To provide centre-based outcome data on obstetric and neonatal complications arising from expectantly managed pregnancies affected by preterm prelabour rupture of membranes (PPROM) before viability. MATERIALS AND METHODS: We collected data on 130 consecutive pregnancies complicated by spontaneous rupture of membranes before 24 weeks gestation, occurring over a 7-year period. These were women who delivered > 24 hours after membrane rupture, and had no signs of chorioamnionitis or advanced labour at admission...
July 1, 2018: Journal of Maternal-fetal & Neonatal Medicine
Bicheng Zhan, Jian Chen, Shaoming Du, Yanzheng Xiong, Jian Liu
BACKGROUND:  Minimally invasive Ivor Lewis esophagectomy (MIILE) is increasingly being used in the treatment of middle or lower esophageal cancer. Hand-sewn purse-string stapled anastomosis is a classic approach in open esophagectomy. However, this procedure is technically difficult under thoracoscopy. The hardest part is delivering the anvil into the esophageal stump. Herein, we report an approach to performing this step under thoracoscopy. METHODS:  A total of 257 consecutive patients who underwent MIILE between April 2013 and July 2017 were analyzed retrospectively...
June 28, 2018: Thoracic and Cardiovascular Surgeon
Shally Awasthi, Krishna K Yadav, Monika Pandey, Abbas A Mahdi, Nidhi Awasthi
BACKGROUND: High morbidity and mortality due to community-acquired pneumonia (CAP) is seen in children under 5 years of age in India. Besides identified risk factors for CAP, there may be a phenotype-genotype association with cytokines, resulting in enhanced inflammatory response resulting in the adverse outcome (AO), namely complications and death. AIM: To assess the association of IL1RA gene polymorphism on serum levels of IL1RA and with AO in children under 5 years of age hospitalized with WHO-defined severe CAP...
June 26, 2018: Pediatric Pulmonology
Jesse Gitaka, Alice Natecho, Humphrey M Mwambeo, Daniel Maina Gatungu, David Githanga, Timothy Abuya
BACKGROUND: Neonatal mortality is a major health burden in Bungoma County with the rate estimated at 31 per 1000 live births and is above the national average of 22 per 1000. Nonetheless, out of the nine sub county hospitals, only two are fairly equipped with necessary infrastructure and skilled personnel to manage neonatal complications such as prematurity, neonatal sepsis, neonatal jaundice, birth asphyxia and respiratory distress syndrome. Additionally, with more than 50% of neonates delivered without skilled attendance, in below par hygiene environments such as home and on the roadsides, with non-existent community based referral system, the situation is made worse...
June 25, 2018: BMC Health Services Research
Tharwat El Zahran, Ziad Kazzi, Ahel Al-Hajj Chehadeh, Riyad Sadek, Mazen J El Sayed
Background: Snakebites lead to at least 421,000 envenomations and result in more than 20,000 deaths per year worldwide. Few reports exist in the Mediterranean region. This study describes demographic and clinical characteristics, treatment modalities, and outcomes of snakebites in Lebanon. Materials and Methods: This was a retrospective chart review of patients who presented with snakebite complaint to the emergency department between January 2000 and September 2014...
April 2018: Journal of Emergencies, Trauma, and Shock
Hua-Kung Wang, Mong-Hong Lee, Yee-Chun Chen, Po-Ren Hsueh, Shan-Chwen Chang
BACKGROUND/PURPOSE: The clinical, epidemiological, and laboratory factors associated with disease severity and mortality from confirmed leptospirosis patients in Taiwan are not well known. This retrospective study examined patients with suspected leptospirosis admitted to En-Chu-Kong Hospital, a regional teaching hospital in northern Taiwan. METHODS: From January 2002 to July 2014, 733 suspected cases were reported to the National Reference Laboratory, 57 of which were identified as laboratory and clinical confirmed...
June 6, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
Ruihua Ma, Pinwen Wu, Qiqing Shi, Dongli Song, Hao Fang
Mechanical ventilation (MV) is an important procedure for the treatment of patients with acute lung injury or acute respiratory distress syndrome in a clinical setting; however, MV can lead to severe complications, including ventilator-induced lung injury (VILI). Telocytes (TCs) can promote tissue repair following injury in the heart, kidneys, and other organs. The aim of this study was to investigate the role of TCs in VILI in mice and the associated mechanisms. By using in vivo studies in mice and in vitro studies in cells, we demonstrated that an airway injection of TCs can reduce the pulmonary inflammatory response and improve the lung function in mice with VILI and promote the proliferation of pulmonary vascular endothelial cells...
June 19, 2018: Acta Biochimica et Biophysica Sinica
Cory N Criss, Ryan Barbaro, Kristy Ann Bauman, Odetola Folafoluwa, Ranjith Vellody, Marcus D Jarboe
INTRODUCTION: This case highlights the successful utilization of a multidisciplinary approach to numerous bilateral bronchopleural fistulae (BPF) using minimally invasive techniques. In this study, we present a previously healthy 14-year-old male hospitalized with 2009 H1N1 influenza and methicillin-resistant Staphylococcus aureus coinfection complicated by severe acute respiratory distress syndrome and multifocal necrotizing pneumonia, with significant lung tissue damage requiring prolonged extracorporeal membrane oxygenation (ECMO) support...
June 19, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Abdulrahman M Al-Nemri, Fahd Alsohime, Asfaq H Shaik, Ghasan A El-Hissi, Mohammed I Al-Agha, Nada F Al-Abdulkarim, Sarar Mohamed
OBJECTIVES: To determine the perinatal and neonatal morbidity related to diabetes associated with pregnancy. METHODS: This is a prospective cohort study conducted at a tertiary university hospital in Central Saudi Arabia. All neonates born to mothers with pregnancy associated diabetes between July 2014 and June 2015 were recruited for the purpose of this study. Infants born at 23 weeks or less, infants who died within 3 hours of delivery, twins, and unbooked pregnant ladies were excluded from the study...
June 2018: Saudi Medical Journal
Xiaoyao Li, Lu Ke, Jie Dong, Bo Ye, Lei Meng, Wenjian Mao, Qi Yang, Weiqin Li, Jieshou Li
BACKGROUND: Unlike western world, gallstones and hypertriglyceridemia (HTG) are among the first two etiologies of acute pancreatitis (AP) in China. But yet, detailed differences in clinical features and outcomes between hypertriglyceridemia and biliary acute pancreatitis have not been well described. METHODS: This retrospective study enrolled 730 acute pancreatitis patients from July 1, 2013 to October 1, 2016 in Jinling Hospital. The causes of the study patients were defined according to specific diagnostic criteria...
June 19, 2018: BMC Gastroenterology
Onnen Moerer, Francesco Vasques, Eleonora Duscio, Francesco Cipulli, Federica Romitti, Luciano Gattinoni, Michael Quintel
Extracorporeal gas exchange is increasingly used for various indications. Among these are refractory acute respiratory failure, including the acute respiratory distress syndrome (ARDS), and the avoidance of ventilator-induced lung injury (VILI) by enabling lung-protective ventilation. Additionally, extracorporeal gas exchange allows the treatment of hypercapnic respiratory failure while helping to unload the respiratory muscles and avoid intubation and invasive ventilation, as well as facilitating weaning from the ventilator...
July 2018: Critical Care Clinics
Thananit Sangkomkamhang, Wilaiphorn Thinkhamrop, Bandit Thinkhamrop, Wongsa Laohasiriwong
Background : The management of multiple injuries is complex. Type and timing of treatment for lower extremity fractures is a controversial subject. Although many studies have demonstrated the safety and effectiveness of early treatment, others have suggested that early definitive stabilization may cause complications, especially with chest and head injuries. The aim of this study was to determine the complications and effects of timing of fixation, and investigate risk factors for complications in multiple injuries patients with lower extremity fractures...
2018: F1000Research
Juan Li, Bo Yu, Wei Wang, Luo, Qian-Ling Dai, Xiao-Qin Gan
OBJECTIVE: To investigate whether intact umbilical cord milking (I-UCM) can aggravate infection or result in other undesirable complications in preterm infants with premature prolonged rupture of membranes (PPROM). METHODS: Neonates vaginally delivered between 28 and 37 weeks' gestation and complicated by PPROM before birth were randomly divided into two groups according to the cord clamping procedure: I-UCM before clamping and immediate cord clamping (ICC). Various parameters of the study participants were compared between the two groups...
June 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
Mary F Stuever, Ryan F Kidner, Floria E Chae, David C Evans
Enteral nutrition (EN) is widely used in intensive care units around the world, but the optimal dosing strategy during the first week of critical illness is still controversial. Numerous studies in the past decade have provided conflicting recommendations regarding the roles of trophic and permissive/intentional underfeeding strategies. Further complicating effective medical decision making is the widespread, yet unintentional and persistent underdelivery of prescribed energy and protein, in addition to the trend for recommending ever-higher amounts of protein delivery...
June 2018: Nutrition in Clinical Practice
Marcelo L M Pereira, Claudio R F Marinho, Sabrina Epiphanio
Malaria is a serious disease and was responsible for 429,000 deaths in 2015. Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is one of the main clinical complications of severe malaria; it is characterized by a high mortality rate and can even occur after antimalarial treatment when parasitemia is not detected. Rodent models of ALI/ARDS show similar clinical signs as in humans when the rodents are infected with murine Plasmodium . In these models, it was shown that the induction of the enzyme heme oxygenase 1 (HO-1) is protective against severe malaria complications, including cerebral malaria and ALI/ARDS...
2018: Frontiers in Cellular and Infection Microbiology
Konstantinos Bouchagier, Evangelos Solakis, Serafeim Klimopoulos, Theano Demesticha, Dimitrios Filippou, Panagiotis Skandalakis
Laparoscopic cholecystectomy is considered as the gold standard in the treatment of gallbladder disease. Laparoscopy presents significant advantages including decreased hospital stay, better aesthetic results, faster rehabilitation, less pain, reduced cost, and increased patient satisfaction. The complications' prevalence is low; however, the overall serious complication rate seems to be higher compared to open cholecystectomy, despite the increasing experience. Diaphragmatic injury following laparoscopic cholecystectomy is an extremely rare complication, and a high index of clinical suspicion is necessary to diagnose this situation that has a variety of clinical presentations and might be life-threatening...
2018: Case Reports in Surgery
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