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https://www.readbyqxmd.com/read/29036213/the-value-of-real-time-continuous-glucose-monitoring-in-premature-infants-of-diabetic-mothers
#1
Hean-Pat Saw, Nai-Wei Yao, Cheng-Di Chiu, Jia-Yuh Chen
To determine the feasibility of using a real-time continuous glucose monitoring system (RTGMS) in intensive care units, our study focus on preterm infants with diabetic mothers owing to their high risk of blood sugar abnormalities. Thirty preterm babies (M = 15 and F = 15; ≤ 36 week gestation age) were studied from within 72 hours of delivery. These babies were admitted to the newborn intensive care and were further categorized into groups based on whether their mothers with or without diabetic mellitus. Blood sugar levels were monitored by both RTGMS and the traditional intermittent arterial line (A-Line) glucose method...
2017: PloS One
https://www.readbyqxmd.com/read/29033859/multi-watt-near-infrared-phototherapy-for-the-treatment-of-comorbid-depression-an-open-label-single-arm-study
#2
Theodore A Henderson, Larry D Morries
BACKGROUND: The treatment of depression has been hampered by low efficacy of antidepressant medications and safety concerns with alternative modalities. Recent work demonstrated that multi-Watt transcranial near-infrared light therapy (NILT) can effectively treat traumatic brain injury (TBI). The current objective is to explore multi-Watt NILT efficacy in a proof-of-concept study as a treatment for depression. METHODS: Thirty-nine sequential patients treated for TBI between March 2013 and May 2017 provided depression self-assessment data and/or were administered the Hamilton depression rating scale...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29031979/doxorubicin-loaded-micelles-of-amphiphilic-diblock-copolymer-with-pendant-dendron-improve-antitumor-efficacy-in-vitro-and-in-vivo-studies
#3
Siew Hui Voon, Chin Siang Kue, Toyoko Imae, Wen Shang Saw, Hong Boon Lee, Lik Voon Kiew, Lip Yong Chung, Shin-Ichi Yusa
Previously reported amphiphilic diblock copolymer with pendant dendron moieties (P71D3) has been further evaluated in tumor-bearing mice as a potential drug carrier. This P71D3-based micelle of an average diameter of 100nm was found to be biocompatible, non-toxic and physically stable in colloidal system up to 15days. It enhanced the in vitro potency of doxorubicin (DOX) in 4T1 breast tumor cells by increasing its uptake, by 3-fold, compared to free DOX. In 4T1 tumor-bearing mice, the tumor growth rate of P71D3/DOX (2mg/kg DOX equivalent) treated group was significantly delayed and their tumor volume was significantly reduced by 1...
October 12, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29031695/-hesitant-compliers-qualitative-analysis-of-concerned-fully-vaccinating-parents
#4
Stephanie L Enkel, Katie Attwell, Thomas L Snelling, Hayley E Christian
OBJECTIVE: Some parents are hesitant about vaccines and yet still vaccinate their children. Vaccine behaviours are not fixed and parents who are concerned but nonetheless adherent to standard schedules could switch to an unconventional schedule, delaying or cherry-picking vaccines. There is a need to better understand vaccine hesitancy in specific contexts, acknowledging cultural and geographical variation, to ensure interventions targeting hesitancy are well directed and received. METHODS: To identify the behaviours, knowledge and attitudes of 'hesitant compliers' in Perth, Western Australia, nine one-on-one in-depth interviews were conducted with vaccinating parents of children (<5 years) who were identified as being hesitant...
October 11, 2017: Vaccine
https://www.readbyqxmd.com/read/29031107/accuracy-precision-and-inter-rater-reliability-of-micro-ct-analysis-of-false-starts-on-bones-a-preliminary-validation-study
#5
Guido Pelletti, Giovanni Cecchetto, Alessia Viero, Paolo Fais, Michael Weber, Diego Miotto, Massimo Montisci, Guido Viel, Chiara Giraudo
Micro computed tomography (micro-CT) has already been proposed as a useful technique for the qualitative analysis of false starts (FS) produced on human bones, although the reliability and the error rate of this technique have not been tested yet, neither for qualitative nor for quantitative assessments. The aim of the present study was to test the morphological agreement, accuracy, precision and inter-rater reliability of micro-CT analysis of FS on bones. The morphological agreement was assessed through the degree of concordance among the 3 independent blind raters in the identification of the shape of 24 FS manually produced on bones by 3 different saws (8 FS for each saw)...
October 6, 2017: Legal Medicine
https://www.readbyqxmd.com/read/29030915/political-transition-and-emergent-forest-conservation-issues-in-myanmar
#6
REVIEW
Graham W Prescott, William J Sutherland, Daniel Aguirre, Matthew Baird, Vicky Bowman, Jake Brunner, Grant M Connette, Martin Cosier, David Dapice, Jose Don T De Alban, Alex Diment, Julia Fogerite, Jefferson Fox, Win Hlaing, Saw Htun, Jack Hurd, Katherine LaJeunesse Connette, Felicia Lasmana, Cheng Ling Lim, Antony Lynam, Aye Chan Maung, Benjamin McCarron, John F McCarthy, William J McShea, Frank Momberg, Myat Su Mon, Than Myint, Robert Oberndorf, Thaung Naing Oo, Jacob Phelps, Madhu Rao, Dietrich Schmidt-Vogt, Hugh Speechly, Oliver Springate-Baginski, Robert Steinmetz, Kirk Talbott, Maung Maung Than, Tint Lwin Thaung, Salai Cung Lian Thawng, Kyaw Min Thein, Shwe Thein, Robert Tizard, Tony Whitten, Guy Williams, Trevor Wilson, Kevin Woods, Alan D Ziegler, Michal Zrust, Edward L Webb
Political and economic transitions have had substantial impacts on forest conservation. Where transitions are underway or anticipated, historical precedent and methods for systematically assessing future trends should be used to anticipate likely threats to forest conservation and design appropriate and prescient policy measures to counteract them. Myanmar is transitioning from an authoritarian, centralized state with a highly regulated economy to a more decentralized and economically liberal democracy and is working to end a long-running civil war...
October 14, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29029604/trauma-burden-in-tanzania-a-one-day-survey-of-all-district-and-regional-public-hospitals
#7
Hendry R Sawe, Juma A Mfinanga, Khalid R Mbaya, Phillip M Koka, Said S Kilindimo, Michael S Runyon, Victor G Mwafongo, Lee A Wallis, Teri A Reynolds
BACKGROUND: Trauma contributes significantly to the burden of disease and mortality throughout the world, but particularly in developing countries. In Tanzania, there is an enormous research gap on trauma; the limited data available reflects realities in cities and areas with moderately- to highly-resourced treatment centers. Our aim was to provide a description of the injury epidemiology across all of Tanzania. Our data will serve as a basis for future larger studies. METHODS: This is a subgroup analysis of a cross-sectional, prospective study of the clinical epidemiology of patients presenting at all public district and regional hospitals in Tanzania...
October 13, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/29029262/chikungunya-fever-outbreak-identified-in-north-bali-indonesia
#8
Kartika Sari, Khin Saw Aye Myint, Ayu Rai Andayani, Putu Dwi Adi, Rama Dhenni, Aditya Perkasa, Chairin Nisa Ma'roef, Ni Putu Diah Witari, Dewi Megawati, Ann M Powers, Ungke Anton Jaya
Background: Chikungunya virus (CHIKV) infections have been reported sporadically within the last 5 years in several areas of Indonesia including Bali. Most of the reports, however, have lacked laboratory confirmation. Method: A recent fever outbreak in a village in the North Bali area was investigated using extensive viral diagnostic testing including both molecular and serological approaches. Results and conclusions: Ten out of 15 acute febrile illness samples were confirmed to have CHIKV infection by real-time PCR or CHIKV-specific IgM enzyme-linked immunosorbent assay (ELISA)...
October 5, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29027513/-sharing-patient-information-with-neighbourhood-social-support-teams-a-legal-perspective
#9
V E T Dörenberg
The beginning of 2015 saw the transition of responsibility for social care, youth care and participation of vulnerable groups in the Netherlands from the government to local authorities. A large majority of municipalities chose to work with neighbourhood social support teams. Their main purpose is to offer integrated care to citizens. Integrated care requires information-sharing between organisations and (healthcare) professionals. Are medical practitioners authorized to share patient information with neighbourhood social support teams? Legal analysis shows that a medical practitioner may play one of the following three roles when sharing information with such teams: the role of referrer, the role of expert or the role of informant...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29026516/ascending-cholangitis-rare-presentation-of-a-ruptured-right-sided-renal-angiomyolipoma
#10
Stefanie M Croghan, Orla McCormack, Anna L Walsh, Ted McDermott
We report the case of a 46-year-old female who presented to the Emergency Department with acute, painful obstructive jaundice, with evidence of secondary ascending cholangitis. Surprisingly, imaging revealed the clinical picture to be caused not by hepatobiliary pathology, but by external compression of the biliary tree from a ruptured renal angiomyolipoma (AML) of the right kidney. The patient remained haemodynamically stable and conservative management saw resolution of biliary obstruction. We believe this to be the first report of a renal AML presenting in this way...
October 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29026358/medicine-in-society-health-project-five-students-journey-to-a-resource-limited-clinic-in-the-haitian-countryside
#11
Aneesh Gupta, Marie Claire Lamb, John Sisney, Chantel Taylor, Timothy Ziethen, Yvens Laborde
BACKGROUND: Five medical students traveled with 4 doctors and a medical photographer to Mayaya, La Victoire, Haiti, as part of a Medicine in Society rotation to provide medical care to the indigenous population. METHODS: Preparation for the trip involved special study in identifying microbes and using blood analysis equipment; work in a clinic for underserved people in the New Orleans, LA, area; background reading; Haitian dialect classes; and development of ideas for streamlining clinic operations...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29024771/development-of-dot-elisa-for-the-detection-of-venoms-of-major-indian-venomous-snakes
#12
Innus K Shaikh, Prashant P Dixit, Balasaheb S Pawade, Indrasen G Waykar
India remained an epicenter for the snakebite-related mortality and morbidities due to widespread agricultural activities across the country and a considerable number of snakebites offended by Indian cobra (Naja naja), common krait (Bungarus caeruleus), Russell's viper (Daboia russelii), and saw-scaled viper (Echis carinatus). Presently, there is no selective test available for the detection of snake envenomation in India before the administration of snake antivenin. Therefore, the present study aimed to develop rapid, sensitive assay for the management of snakebite, which can detect venom, responsible snake species and serve as a tool for the reasonable administration of snake antivenin, which have scarcity across the world...
October 9, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29024079/the-preadolescent-acne-microbiome-a-prospective-randomized-pilot-study-investigating-characterization-and-effects-of-acne-therapy
#13
Carrie C Coughlin, Shane M Swink, Joseph Horwinski, Georgia Sfyroera, Julia Bugayev, Elizabeth A Grice, Albert C Yan
BACKGROUND/OBJECTIVES: Acne, a common pediatric disease, tends to be more comedonal in preadolescents, whereas older individuals are more likely to have inflammatory lesions in addition to comedones. Thus the microbiome of preadolescents may be different. In this pilot study we aimed to characterize the preadolescent acne microbiome, compare the microbiome in preadolescents with and without acne, and investigate changes in the microbiome after topical treatment with benzoyl peroxide or a retinoid in a small cohort of preadolescents...
October 11, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29023559/the-relationship-between-orexin-levels-and-blood-pressure-changes-in-patients-with-narcolepsy
#14
Mariusz Sieminski, Kamil Chwojnicki, Tomi Sarkanen, Markku Partinen
STUDY OBJECTIVE: Narcolepsy type 1 (NT1) is caused by a deficiency or absence of the neurotransmitter orexin. NT1 is also associated with a reduced nocturnal "dipping" of blood pressure (BP). The study objective was to analyze whether nocturnal BP values differed in patients depleted of orexin, versus those in whom production was preserved. METHODS: We performed a retrospective analysis of the polysomnographic recordings, orexin levels, and BP values of patients with NT1...
2017: PloS One
https://www.readbyqxmd.com/read/29023499/understanding-the-perceived-logic-of-care-by-vaccine-hesitant-and-vaccine-refusing-parents-a-qualitative-study-in-australia
#15
Paul R Ward, Katie Attwell, Samantha B Meyer, Philippa Rokkas, Julie Leask
In terms of public health, childhood vaccination programs have benefits that far outweigh risks. However, some parents decide not to vaccinate their children. This paper explores the ways in which such parents talked about the perceived risks and benefits incurred by vaccinating (or not vaccinating) their children. Between 2013-2016 we undertook 29 in-depth interviews with non-vaccinating and/or 'vaccine hesitant' parents in Australia. Interviews were conducted in an open and non-judgmental manner, akin to empathic neutrality...
2017: PloS One
https://www.readbyqxmd.com/read/29019820/split-overlapping-genioplasty-surgical-technique-morphological-and-radiological-long-term-outcomes
#16
Flore Roul-Yvonnet, Julien Quilichini, Patrick Leyder
BACKGROUND: The overlapping bone flap genioplasty, described by Tessier, was developed to treat major retrognathia or long and retruded chins. For 15 years, we have used a modified version of this technique to avoid its drawbacks. The aim of this article is to describe our modification and evaluate the long-term morphologic and radiologic outcomes. PATIENTS AND METHOD: The authors included every split-overlapping genioplasty performed in our department between 2004 and 2014...
October 10, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29018115/kaposi-s-sarcoma-associated-herpesvirus-increases-pd-l1-and-proinflammatory-cytokine-expression-in-human-monocytes
#17
Kurtis M Host, Sarah R Jacobs, John A West, Zhigang Zhang, Lindsey M Costantini, Charles M Stopford, Dirk P Dittmer, Blossom Damania
Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with the human malignancy Kaposi's sarcoma and the lymphoproliferative disorders primary effusion lymphoma and multicentric Castleman's disease. KSHV establishes lytic infection of monocytes in vivo, which may represent an important cellular reservoir during KS disease progression. KS tumors consist of latently infected endothelial cells; however, lytic phase gene products are important for KS onset. Early KS lesion progression is driven by proinflammatory cytokines supplied by immune cell infiltrates including T cells and monocytes...
October 10, 2017: MBio
https://www.readbyqxmd.com/read/29017035/bee-cognition
#18
Lars Chittka
Maeterlinck did not mean to suggest that honeybees rival humans in intelligence - rather he saw in the bee a qualitatively different form of intelligence, tailored to the challenges of a profoundly different kind of society and lifestyle. Insects are strange "aliens from inner space", with sensory and cognitive worlds wholly different from our own. The 19(th) century discovery that ants can detect ultraviolet light triggered a golden age in the exploration of the diversity of sensory systems of insects (and indeed other animals), identifying such abilities as magnetic compasses, electrosensitivity, polarization vision, and peculiar locations for sense organs such as the infrared sensors on the abdomens of some beetles or photoreceptors on the genitalia of some butterflies...
October 9, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29016291/chikungunya-detection-during-dengue-outbreak-in-sumatra-indonesia-clinical-manifestations-and-virological-profile
#19
R Tedjo Sasmono, Aditya Perkasa, Benediktus Yohan, Sotianingsih Haryanto, Frilasita A Yudhaputri, Rahma F Hayati, Chairin Nisa Ma'roef, Jeremy P Ledermann, Khin Saw Aye Myint, Ann M Powers
Chikungunya fever (CHIK) is an acute viral infection caused by infection with chikungunya virus (CHIKV). The disease affects people in areas where certain Aedes species mosquito vectors are present, especially in tropical and subtropical countries. Indonesia has witnessed CHIK disease since the early 1970s with sporadic outbreaks occurring throughout the year. The CHIK clinical manifestation, characterized by fever, headache, and joint pain, is similar to that of dengue (DEN) disease. During a molecular study of a DEN outbreak in Jambi, Sumatra, in the early 2015, DEN-negative samples were evaluated for evidence of CHIKV infection...
September 25, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28994884/trauma-of-the-hand-from-circular-saw-table-a-series-of-a-130-cases
#20
Yafa Hadj Hassine, Mohamed Hmid, Walid Baya
INTRODUCTION: Trauma of the hand from a circular saw table is a common occurrence in developing countries it tends to occur in young hand working people and it causes a serious lesions. METHODS: It was a retrospective series about a 130 cases of hand trauma from circular saw table. Epidemiological features, treatment, and permanent disabilities left by hand trauma from circular saw table were studied to identify ways to prevent such an accident. RESULTS: The average age was 31...
December 2016: La Tunisie Médicale
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