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tetralogy of fallot adult

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https://www.readbyqxmd.com/read/28483478/left-aberrant-subclavian-artery-systematic-study-in-adult-patients
#1
Paweł Tyczyński, Ilona Michałowska, Rafał Wolny, Piotr Dobrowolski, Hubert Łazarczyk, Justyna Rybicka, Piotr Hoffman, Adam Witkowski
BACKGROUND: Left aberrant subclavian artery (LASA), is a type of right aortic arch (RAA) branching, which takes-off distally to the right subclavian artery and usually crosses behind the esophagus to the left upper limb. Taking into account the rarity of RAA, LASA is much more rarely seen than the right aberrant subclavian artery (RASA) originating from the left aortic arch. However, RAA may be associated with much more frequent presence of LASA, than left aortic arch with RASA. Anatomical LASA characteristics were not described up to date...
April 25, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28471080/twenty-years-of-experience-with-intraoperative-pulmonary-artery-stenting
#2
Jeffrey D Zampi, Emefah Loccoh, Aimee K Armstrong, Sunkyung Yu, Ray Lowery, Albert P Rocchini, Jennifer C Hirsch-Romano
OBJECTIVES: To describe our 20-year experience with intraoperative pulmonary artery (PA) stent placement and evaluate long-term patient outcomes, specifically the need and risk factors for reintervention. BACKGROUND: Intraoperative PA stent placement is an alternative to surgical patch arterioplasty and percutaneous angioplasty or stent placement to treat branch PA stenosis. METHODS: We performed a retrospective review of all intraoperative PA stents placed at our institution from 1994-2013...
May 4, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28464509/forced-vital-capacity-predicts-morbidity-and-mortality-in-adults-with-repaired-tetralogy-of-fallot
#3
Katie E Cohen, Matthew W Buelow, Jennifer Dixon, Ruta Brazauskas, Scott B Cohen, Michael G Earing, Salil Ginde
OBJECTIVE: Abnormal lung function characterized by a reduced forced vital capacity (FVC) is common in adults with repaired tetralogy of Fallot (TOF) and is associated with previous thoracotomies and sternotomies. The impact of abnormal lung function on clinical outcomes in adult patients with repaired TOF is unclear. The aim of this study was to determine the impact of abnormal lung function on the outcome of hospitalization and death in adults with repaired TOF when analyzed with other traditional cardiac risk factors...
May 2, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28457242/clinical-aspects-and-ablation-of-ventricular-arrhythmias-in-tetralogy-of-fallot
#4
REVIEW
Katja Zeppenfeld, Adrianus P Wijnmaalen
Life expectancy of patients with rToF has considerably improved due to refined surgical interventions. Monomorphic fast VTs are frequently encountered in adult patients with rToF. The dominant substrate of VT is anatomical isthmuses bordered by surgical incisions, patch material and valve annuli. Substrate based ablation strategies aim to transect all slow conducting anatomical isthmuses (SCAI) as identified by electroanatomical mapping. Procedural success is defined as non-inducibility of VT and confirmed conduction block over the SCAI resulting in long-term VT free survival in most patients...
June 2017: Cardiac Electrophysiology Clinics
https://www.readbyqxmd.com/read/28457237/sudden-cardiac-death-in-adult-congenital-heart-disease
#5
REVIEW
Pablo Ávila, Marie-A Chaix, Blandine Mondésert, Paul Khairy
Sudden death of presumed arrhythmic etiology is a leading cause of mortality in adults with congenital heart disease. Anticipated benefits of the implantable cardioverter-defibrillator (ICD) must be weighed against high complication rates. Without robust evidence from randomized trials, caregivers face difficult decisions in selecting appropriate candidates. Although secondary prevention indications are often clear-cut, risk stratification for primary prevention ICDs is more challenging. Factors associated with sudden death in patients with tetralogy of Fallot are reasonably consistent across studies...
June 2017: Cardiac Electrophysiology Clinics
https://www.readbyqxmd.com/read/28455532/left-ventricular-stiffness-in-adolescents-and-young-adults-with-repaired-tetralogy-of-fallot
#6
Clement Kwong-Man Yu, Wilfred Hing-Sang Wong, Vivian Wing-Yi Li, Yiu-Fai Cheung
Left ventricular (LV) remodeling after tetralogy of Fallot (TOF) repair may influence LV stiffness. We hypothesized that LV stiffness is altered after TOF repair and related to myocardial calibrated integrated backscatter (cIB) and LV diastolic myocardial deformation. Seventy-seven TOF patients and 80 controls were studied. LV stiffness was assessed by diastolic wall strain (DWS) as defined by (LVPWsystole-LVPWdiastole)/LVPWsystole, where LVPW is LV posterior wall thickness, and stiffness index as defined by (E/e/LV end-diastolic dimension), where E and e are respectively early diastolic transmitral inflow and mitral annular velocities...
April 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28454836/right-ventricular-dysfunction-in-tetralogy-of-fallot-inhibition-of-the-renin-angiotensin-aldosterone-system-redefine-trial-rationale-and-design-of-a-randomized-double-blind-placebo-controlled-clinical-trial
#7
Jouke P Bokma, Michiel M Winter, Esmée M Kornaat, Hubert W Vliegen, Arie P van Dijk, Joost P van Melle, Folkert J Meijboom, Martijn C Post, Jacqueline K Berbee, Aeilko H Zwinderman, Barbara J M Mulder, Berto J Bouma
Renin-angiotensin-aldosterone system (RAAS) inhibition with angiotensin II receptor blockers or angiotensin-converting enzyme inhibitors is beneficial in patients with acquired left ventricular dysfunction. Adult patients with tetralogy of Fallot (TOF) with right ventricular (RV) dysfunction are at high risk for heart failure, arrhythmias, and sudden cardiac death. However, the efficacy of RAAS inhibition has not been established in these patients. METHODS: The REDEFINE is an investigator-initiated, multicenter, prospective, randomized, double-blind, placebo-controlled trial to study the effects of the angiotensin II receptor blocker losartan (target dosage of 150 mg once daily) in adult patients with TOF...
April 2017: American Heart Journal
https://www.readbyqxmd.com/read/28402450/sudden-cardiac-death-in-adults-with-congenital-heart-disease-does-qrs-complex-fragmentation-discriminate-in-structurally-abnormal-hearts
#8
Jim T Vehmeijer, Zeliha Koyak, Jouke P Bokma, Werner Budts, Louise Harris, Barbara J M Mulder, Joris R de Groot
Aims: Sudden cardiac death (SCD) causes a large portion of all mortality in adult congenital heart disease (ACHD) patients. However, identification of high-risk patients remains challenging. Fragmented QRS-complexes (fQRS) are a marker for SCD in patients with acquired heart disease but data in ACHD patients are lacking. We therefore aim to evaluate the prognostic value of fQRS for SCD in ACHD patients. Methods and results: From a multicentre cohort of 25 790 ACHD patients, we included tachyarrhythmic SCD cases (n = 147), and controls (n = 266) matched by age, gender, congenital defect and (surgical) intervention...
April 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28364481/postoperative-interventricular-septal-haematoma-following-tetralogy-of-fallot-repair-and-perimembranous-ventricular-septal-defect-repair
#9
Fiona J Bailey, Salim G M Jivanji, Martin Kostolny
Interventricular septal haematoma is a rare postoperative complication in congenital heart surgery. We present one case of a 6-month-old after tetralogy of Fallot repair and 1 case of a 10-month-old after ventricular septal defect repair. Both were noted to have interventricular septal haematoma on intraoperative transoesophageal and postoperative echocardiogram. Although multiple previous reports, mainly in adults, have suggested aggressive intervention, both these cases were managed conservatively, highlighting the management and evolution of a rare postoperative complication in the paediatric population...
February 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28347634/ten-year-outcomes-of-monomorphic-ventricular-tachycardia-catheter-ablation-in-repaired-tetralogy-of-fallot
#10
Mikaël Laredo, Robert Frank, Xavier Waintraub, Estelle Gandjbakhch, Laurence Iserin, Sebastien Hascoët, Caroline Himbert, Yves Gallais, Françoise Hidden-Lucet, Guillaume Duthoit
BACKGROUND: Monomorphic ventricular tachycardia (MVT) is common in adults with repaired tetralogy of Fallot (TOF), and is associated with sudden cardiac death. Management of MVT is not defined, and results of catheter ablation (CA) are limited. AIMS: To evaluate long-term outcomes of MVT CA in repaired TOF. METHODS: Thirty-four patients (mean age 32±10.3 years; 59% male) with repaired TOF underwent CA for symptomatic MVT between 1990 and 2012 in our centre; direct-current ablation (DCA) was used in 6%, radiofrequency followed by DCA in 29% and radiofrequency alone in 65%...
March 24, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28329231/cardiac-protective-effects-of-remote-ischaemic-preconditioning-in-children-undergoing-tetralogy-of-fallot-repair-surgery-a-randomized-controlled-trial
#11
Qingping Wu, Tingting Wang, Shiqiang Chen, Quanjun Zhou, Haobo Li, Na Hu, Yinglu Feng, Nianguo Dong, Shanglong Yao, Zhengyuan Xia
Aims: Remote ischaemic preconditioning (RIPC) by inducing brief ischaemia in distant tissues protects the heart against myocardial ischaemia-reperfusion injury (IRI) in children undergoing open-heart surgery, although its effectiveness in adults with comorbidities is controversial. The effectiveness and mechanism of RIPC with respect to myocardial IRI in children with tetralogy of Fallot (ToF), a severe cyanotic congenital cardiac disease, undergoing open heart surgery are unclear. We hypothesized that RIPC can confer cardioprotection in children undergoing ToF repair surgery...
February 18, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28327874/left-atrial-deformation-analysis-in-patients-with-corrected-tetralogy-of-fallot-by-3d-speckle-tracking-echocardiography-from-the-magyar-path-study
#12
Kálmán Havasi, Péter Domsik, Anita Kalapos, Jackie S McGhie, Jolien W Roos-Hesselink, Tamás Forster, Attila Nemes
Background: Three-dimensional (3D) echocardiography coupled with speckle-tracking echocardiographic (STE) capability is a novel methodology which has been demontrated to be useful for the assessment of left atrial (LA) volumes and functional properties. There is increased scientific interest on myocardial deformation analysis in adult patients with corrected tetralogy of Fallot (cTOF). Objectives: To compare LA volumes, volume-based functional properties and strain parameters between cTOF patients and age- and gender-matched healthy controls...
February 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28303658/anchor-balloon-buddy-wire-and-wire-and-sheath-techniques-to-deploy-percutaneous-pulmonary-valves-in-tetralogy-of-fallot-patients
#13
Ruchit R Shah, Paul Poommipanit, Mark A Law, Zahid Amin
Advances in surgical techniques in tetralogy of Fallot (TOF) patients have improved survival of these patients into adulthood. The procedure requires right ventricular outflow tract or trans-annular patch with resultant pulmonary stenosis and/or regurgitation. As such, adult patients seen with this condition may have increasing right ventricular hypertrophy and/or right ventricular dilation. Recently, the Sapien XT valve (Edwards Lifesciences, CA) was approved by the FDA for pulmonary implantation. In some cases, advancing the valve in right ventricular outflow tract is difficult...
March 17, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28292861/assessment-of-diffuse-ventricular-myocardial-fibrosis-using-native-t1-in-children-with-repaired-tetralogy-of-fallot
#14
Deane Yim, Eugenie Riesenkampff, Pablo Caro-Dominguez, Shi-Joon Yoo, Mike Seed, Lars Grosse-Wortmann
BACKGROUND: Myocardial fibrosis is linked with adverse clinical outcomes in adults after tetralogy of Fallot repair (rTOF). Native T1 times (T1) by cardiac magnetic resonance have been shown to be a surrogate marker of diffuse myocardial fibrosis. The objective was to quantify native T1 in children post-rTOF and to evaluate their relationship with surgical, imaging, and clinical factors. METHODS AND RESULTS: A retrospective cross-sectional study was performed. Midventricular native T1 were obtained in 100 children post-rTOF using a modified look-locker inversion recovery cardiac magnetic resonance sequence and compared with 35 pediatric controls...
March 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28292589/tricuspid-valve-repair-and-pulmonary-valve-replacement-in-adults-with-repaired-tetralogy-of-fallot
#15
François Roubertie, Pierre-Emmanuel Séguéla, Zakaria Jalal, Xavier Iriart, Xavier Roques, Bernard Kreitmann, Mohammed Al-Yamani, Xavier Pillois, Jean-Benoît Thambo
BACKGROUND: Pulmonary valve replacement (PVR) often is performed in adults with repaired tetralogy of Fallot (TOF). For patients who have tricuspid regurgitation (TR), tricuspid valve (TV) repair associated to PVR is still debated. OBJECTIVE: We sought to evaluate perioperative factors related to TV repair when performed at the time of PVR in patients with repaired TOF. METHODS: We retrospectively reviewed 104 patients with repaired TOF (or its equivalent) who underwent PVR (2002-2014)...
February 10, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28276717/rv-to-pa-conduits-impact-of-transcatheter-pulmonary-valve-replacement-in-adults-a-national-register-study
#16
Kristofer Skoglund, Gunnar Svensson, Ulf Thilén, Mikael Dellborg, Peter Eriksson
OBJECTIVE: The use of a conduit is an established surgical method for reconstruction of the right ventricular outflow tract in congenital heart disease; however, its limited durability makes reintervention almost inevitable. We studied the trends in new implantation, reoperation, and transcatheter pulmonary valve replacement (TPVR) from a Swedish national perspective. DESIGN AND RESULTS: The Swedish registry of congenital heart disease (SWEDCON) was used to collect data...
February 15, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/28275877/cardiovascular-autonomic-dysfunction-and-carotid-stiffness-in-adults-with-repaired-tetralogy-of-fallot
#17
Marko Novaković, Katja Prokšelj, Vito Starc, Borut Jug
PURPOSE: Adults after surgical repair of tetralogy of Fallot (ToF) may have impaired vascular and cardiac autonomic function. Thus, we wanted to assess interrelations between heart rate variability (HRV) and heart rate recovery (HRR), as parameters of cardiac autonomic function, and arterial stiffness, as a parameter of vascular function, in adults with repaired ToF as compared to healthy controls. METHODS: In a case-control study of adults with repaired ToF and healthy age-matched controls we measured: 5-min HRV variability (with time and frequency domain data collected), carotid artery stiffness (through pulse-wave analysis using echo-tracking ultrasound) and post-exercise HRR (cycle ergometer exercise testing)...
March 8, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28270260/what-is-the-diagnostic-value-of-the-paediatric-exercise-tolerance-test-results-from-a-uk-centre
#18
Magdalena A Sajnach-Menke, Sarah C Walpole
Purpose The aim of this study was to determine whether the exercise tolerance test can provide diagnostic and prognostic information regarding children and young adults and help predict outcome. METHODS: A total of 87 patients, aged 7-29 years (median 13, mean 13.4) were selected retrospectively. They underwent exercise test at the Freeman Hospital from December, 2015 to May, 2016. There were two groups of patients - 46 had symptoms such as chest pain, palpitations, syncope, or dyspnoea on exertion and no cardiac diagnosis, and 40 patients had a cardiac diagnosis such as hypertrophic cardiomyopathy, transposition of the great arteries with post-arterial switch operation, aortic stenosis or regurgitation, tetralogy of Fallot, abnormal coronary arteries, Wolff-Parkinson-White syndrome, or supraventricular tachycardia...
March 8, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28268081/prognostic-value-of-left-atrial-size-and-function-in-adults-with-tetralogy-of-fallot
#19
Vivan J M Baggen, Anne-Rose W Schut, Judith A A E Cuypers, Maarten Witsenburg, Eric Boersma, Annemien E van den Bosch, Jolien W Roos-Hesselink
BACKGROUND: Left atrial (LA) size predicts cardiovascular outcome in chronic heart failure. Its prognostic value in adults with repaired tetralogy of Fallot (ToF) is unknown. This study therefore investigated the association of LA size and function with cardiovascular events in adults with ToF. METHODS: Clinically stable adults with ToF who visited the outpatient clinic between 2011 and 2013 underwent echocardiography and were prospectively followed for the occurrence of death, heart failure, hospitalizations, arrhythmia, thromboembolic events, and re-interventions...
March 3, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28258242/successful-cardiac-transplantation-outcomes-in-patients-with-adult-congenital-heart-disease
#20
Jonathan N Menachem, Jessica R Golbus, Maria Molina, Jeremy A Mazurek, Nicole Hornsby, Pavan Atluri, Stephanie Fuller, Edo Y Birati, Yuli Y Kim, Lee R Goldberg, Joyce W Wald
OBJECTIVES: The purpose of our study is (1) to characterise patients with congenital heart disease undergoing heart transplantation by adult cardiac surgeons in a large academic medical centre and (2) to describe successful outcomes associated with our multidisciplinary approach to the evaluation and treatment of adults with congenital heart disease (ACHD) undergoing orthotopic heart transplantation (OHT). BACKGROUND: Heart failure is the leading cause of death in patients with ACHD leading to increasing referrals for OHT...
March 3, 2017: Heart: Official Journal of the British Cardiac Society
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