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https://www.readbyqxmd.com/read/29137971/clearance-of-schistosome-parasites-by-resistant-genotypes-at-a-single-genomic-region-in-biomphalaria-glabrata-snails-involves-cellular-components-of-the-hemolymph
#1
Euan R O Allan, Benjamin Gourbal, Camila B Dores, Anais Portet, Christopher J Bayne, Michael S Blouin
Schistosomiasis is one of the most detrimental neglected tropical diseases. Controlling the spread of this parasitic illness requires effective sanitation, access to chemotherapeutic drugs, and control over populations of the freshwater snails, such as Biomphalaria glabrata, that are essential intermediate hosts for schistosomes. Effectively controlling this disease, while minimising ecological implications of such control, will require an extensive understanding of the immunological interactions between schistosomes and their molluscan intermediate hosts...
November 12, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/29121918/-no-generics-doctor-the-perspective-of-general-practitioners-in-two-french-regions
#2
Béatrice Riner, Adèle Bussy, Jeannie Hélène-Pelage, Nycrees Moueza, Sébastien Lamy, Philippe Carrère
BACKGROUND: Generic medicines are essential to controlling health expenditures. Their market share is still small in France. The discourse and practices of prescribers may play a major role in their use. The purpose of this study was to explore the knowledge, attitudes and practices of general practitioners (GPs) toward generic medicines in two French regions with the lowest penetration rate of these products. METHODS: An observational study was carried out from October 2015 to February 2016 in Guadeloupe and Martinique...
November 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29120835/characteristics-of-invasive-breast-cancer-and-overall-survival-of-patients-eligible-for-mass-breast-cancer-screening-in-guadeloupe-compared-to-those-of-the-preceding-age-group
#3
Philippe Kadhel, Daphné Borja De Mozota, Stéphanie Gaumond, Jacqueline Deloumeaux
BACKGROUND: Mass breast cancer screening is offered to French women between the ages of 50 and 74. In the French overseas department of Guadeloupe, where the population is of mostly African ancestry, a low age at diagnosis of breast cancer has been reported, as for African-Americans. This raises the question of whether breast cancer is more aggressive in the age group preceding that eligible for mass screening (40-49) in Guadeloupe. METHODS: We compared the tumor-related prognostic factors, first line therapy and overall survival rates of breast cancer cases diagnosed between the 40-49 and 50-74 age groups, based on reports of the cancer registry of Guadeloupe for the period 2008-2013...
October 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/29118595/a-taxonomic-review-of-the-selenophori-group-coleoptera-carabidae-harpalini-in-the-west-indies-with-descriptions-of-new-species-and-notes-about-classification-and-biogeography
#4
Danny Shpeley, Wesley Hunting, George E Ball
Primarily a taxonomic review of the West Indian elements of the selenophorine Harpalini, this paper includes a classification, a key, descriptions and illustrations of taxa, re-rankings, and new synonymies. In total, 45 species and subspecies are treated, six of which are described as new. A new genus and new species are as follows, with type localities in parentheses: Paraulacoryssusgen. n., (type species Selenophorus puertoricensis Mutchler, 1934); Neodiachipteryx davidsonisp. n., (Zamba, Dominican Republic); Selenophorus spinosussp...
2017: ZooKeys
https://www.readbyqxmd.com/read/29107743/allelic-variation-partially-regulates-galactose-dependent-hydrogen-peroxide-release-from-circulating-hemocytes-of-the-snail-biomphalaria-glabrata
#5
Euan R O Allan, Michael S Blouin
Freshwater snails are the intermediate hosts for numerous parasitic worms that are detrimental to human and agricultural health. Understanding the immune responses of these snails could be vital for finding ways to block transmission of those parasites. Allelic variation in a recently discovered genomic region in the snail, Biomphalaria glabrata, influences their susceptibility to schistosomes. Here we tested whether genes in that region, termed the Guadeloupe Resistance Complex (GRC), are involved in recognition of common pathogen-associated molecules that have been shown to be stimulants of the hydrogen peroxide defense pathway...
October 28, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29053358/bioinvasion-triggers-rapid-evolution-of-life-histories-in-freshwater-snails
#6
Elodie Chapuis, Thomas Lamy, Jean-Pierre Pointier, Nicolas Juillet, Adeline Ségard, Philippe Jarne, Patrice David
Biological invasions offer interesting situations for observing how novel interactions between closely related, formerly allopatric species may trigger phenotypic evolution in situ. Assuming that successful invaders are usually filtered to be competitively dominant, invasive and native species may follow different trajectories. Natives may evolve traits that minimize the negative impact of competition, while trait shifts in invasives should mostly reflect expansion dynamics, through selection for colonization ability and transiently enhanced mutation load at the colonization front...
November 2017: American Naturalist
https://www.readbyqxmd.com/read/28921374/prostate-cancer-clinical-presentation-incidence-mortality-and-survival-in-guadeloupe-over-the-period-2008-2013-from-a-population-based-cancer-registry
#7
J Deloumeaux, B Bhakkan, R Eyraud, F Braud, N Manip M'Ebobisse, P Blanchet, L Brureau
PURPOSE: The Caribbean population of Guadeloupe has one of the highest incidence rates of prostate cancer worldwide. In 2008, a population-based cancer registry was set up for the monitoring of cancer incidence in the aftermath of the environmental pollution with chlordecone, a persistent organochlorine insecticide formerly used in banana plantations. We describe the clinical presentation, incidence, mortality and survival of prostate cancer for the period 2008-2013. METHODS: The Guadeloupe cancer registry has been routinely collecting all incident cases of cancer since 2008...
November 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28838639/effect-of-acute-zika-virus-infection-on-sperm-and-virus-clearance-in-body-fluids-a-prospective-observational-study
#8
Guillaume Joguet, Jean-Michel Mansuy, Giulia Matusali, Safouane Hamdi, Marie Walschaerts, Lynda Pavili, Stefanie Guyomard, Nadia Prisant, Pierre Lamarre, Nathalie Dejucq-Rainsford, Christophe Pasquier, Louis Bujan
BACKGROUND: Evidence of human sexual transmission during Zika virus emergence is a matter of concern, particularly in procreation, but to date, kinetics of seminal shedding and the effects of infection on human reproductive function have not been described. To investigate the effects of Zika virus infection on semen and clearance of Zika virus from semen and body fluids, we aimed to study a cohort of Zika virus-infected men. METHODS: This prospective observational study recruited men presenting with acute Zika virus infection at Pointe-à-Pitre University Hospital in Guadeloupe, French Caribbean, where a Zika virus outbreak occurred between April and November, 2016...
November 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28804479/molecular-characterization-of-arbuscular-mycorrhizal-fungi-in-an-agroforestry-system-reveals-the-predominance-of-funneliformis-spp-associated-with-colocasia-esculenta-and-pterocarpus-officinalis-adult-trees-and-seedlings
#9
Alexandre Geoffroy, Hervé Sanguin, Antoine Galiana, Amadou Bâ
Pterocarpus officinalis (Jacq.) is a leguminous forestry tree species endemic to Caribbean swamp forests. In Guadeloupe, smallholder farmers traditionally cultivate flooded taro (Colocasia esculenta) cultures under the canopy of P. officinalis stands. The role of arbuscular mycorrhizal (AM) fungi in the sustainability of this traditional agroforestry system has been suggested but the composition and distribution of AM fungi colonizing the leguminous tree and/or taro are poorly characterized. An in-depth characterization of root-associated AM fungal communities from P...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28769627/disjunctitermes-insularis-a-new-soldierless-termite-genus-and-species-isoptera-termitidae-apicotermitinae-from-guadeloupe-and-peru
#10
Rudolf H Scheffrahn, Tiago F Carrijo, Anthony C Postle, Francesco Tonini
Disjunctitermes insularisgen. n. & sp. n. is described from workers collected on Guadeloupe and in Peru and is the first soldierless termite found on a deep-water island. As with many soldierless and soil-feeding termite species, the enteric valve morphology is an essential diagnostic character of D. insularis. The D. insularis sequence cluster, derived from a barcode analysis with twelve other described genera of New World Apicotermitinae, is well resolved. Results of a stochastic dynamic spread model suggest that the occurrence of D...
2017: ZooKeys
https://www.readbyqxmd.com/read/28754134/occurrence-of-a-novel-mastrevirus-in-sugarcane-germplasm-collections-in-florida-guadeloupe-and-r%C3%A3-union
#11
Wardatou Boukari, Ricardo I Alcalá-Briseño, Simona Kraberger, Emmanuel Fernandez, Denis Filloux, Jean-Heinrich Daugrois, Jack C Comstock, Jean-Michel Lett, Darren P Martin, Arvind Varsani, Philippe Roumagnac, Jane E Polston, Philippe C Rott
BACKGROUND: In Africa and Asia, sugarcane is the host of at least seven different virus species in the genus Mastrevirus of the family Geminiviridae. However, with the exception of Sugarcane white streak virus in Barbados, no other sugarcane-infecting mastrevirus has been reported in the New World. Conservation and exchange of sugarcane germplasm using stalk cuttings facilitates the spread of sugarcane-infecting viruses. METHODS: A virion-associated nucleic acids (VANA)-based metagenomics approach was used to detect mastrevirus sequences in 717 sugarcane samples from Florida (USA), Guadeloupe (French West Indies), and Réunion (Mascarene Islands)...
July 28, 2017: Virology Journal
https://www.readbyqxmd.com/read/28746998/bioaccumulation-distribution-and-elimination-of-chlordecone-in-the-giant-freshwater-prawn-macrobrachium-rosenbergii-field-and-laboratory-studies
#12
Anne Lafontaine, Eric Gismondi, Nathalie Dodet, Célia Joaquim-Justo, Céline Boulangé-Lecomte, Fanny Caupos, Soazig Lemoine, Laurent Lagadic, Joëlle Forget-Leray, Jean-Pierre Thomé
Chlordecone is a persistent organochlorine pesticide that has been widely used in Guadeloupe (French West Indies) to control the banana weevil Cosmopolites sordidus from 1972 to 1993. A few years after its introduction, widespread contamination of soils, rivers, wild animals and aquatic organisms was reported. Although high chlordecone concentrations have been reported in several crustacean species, its uptake, internal distribution, and elimination in aquatic species have never been described. This study aimed at investigating the accumulation and tissue distribution of chlordecone in the giant freshwater prawn Macrobrachium rosenbergii, using both laboratory (30 days exposure) and field (8 months exposure) approaches...
October 2017: Chemosphere
https://www.readbyqxmd.com/read/28722564/guillain-barr%C3%A3-syndrome-and-chikungunya-description-of-all-cases-diagnosed-during-the-2014-outbreak-in-the-french-west-indies
#13
Stephanie Balavoine, Mathilde Pircher, Bruno Hoen, Cecile Herrmann-Storck, Fatiha Najioullah, Benjamin Madeux, Aissatou Signate, Ruddy Valentino, Annie Lannuzel, Magali Saint Louis, Sylvie Cassadou, André Cabié, Kinda Schepers
The Guillain-Barré syndrome (GBS) has been reported as a possible complication of acute chikungunya infection. The chikungunya epidemics, which occurred in Martinique and Guadeloupe in 2014, affected 308,000 people in these two islands. GBS occurred during or immediately after acute chikungunya infection in 13 patients (10 men, three women; mean age: 61 years). Median time from acute chikungunya to GBS onset was 9 days. Twelve patients were treated with intravenous polyvalent immunoglobulins, nine of whom improved within 7 days...
August 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28711467/retrospective-study-of-jellyfish-envenomation-in-emergency-wards-in-guadeloupe-between-2010-and-2016-when-to-diagnose-irukandji-syndrome
#14
Djoudi Bouyer-Monot, Stéphane Pelczar, Serge Ferracci, Denis Boucaud-Maitre
BACKGROUND: In Guadeloupe (French West Indies), many marine envenomation cases by jellyfish are observed. Some of them might induce an Irukandji syndrome (IS). The aim of this study was to analyse the clinical features of IS from the envenomation cases in the two public hospitals in Guadeloupe, and to compare them to non-IS stings. METHODS: All jellyfish envenomation cases between the 1st of January 2010 and the 1st of September 2016, from the emergencies data-base, have been extracted...
July 13, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28699005/study-of-chlordecone-desorption-from-activated-carbons-and-subsequent-dechlorination-by-reduced-cobalamin
#15
Ronald Ranguin, Axelle Durimel, Reeka Karioua, Sarra Gaspard
Since 1972, the French departments of Guadeloupe and Martinique have intensively used organochlorinated pesticides such as chlordecone (CLD) and hexachlorocyclohexane (HCH) isomers to prevent the proliferation of banana weevil (Cosmopolite sordidus). These molecules are stable in the environment, leading to a continuous contamination of soils, water, and food chain in the banana-producing areas. In these polluted areas, water treatment plants are equipped with activated carbon (AC) filters. In order to improve treatment of CLD-contaminated waters by AC, CLD adsorption and desorption kinetic studies are carried out using different ACs produced from sugar cane bagasse as adsorbents and subsequent CLD degradation is performed using reduced vitamin B12 (VB12)...
July 11, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28692894/occurrence-survey-and-spatial-distribution-of-perfluoroalkyl-and-polyfluoroalkyl-surfactants-in-groundwater-surface-water-and-sediments-from-tropical-environments
#16
Gabriel Munoz, Pierre Labadie, Fabrizio Botta, François Lestremau, Benjamin Lopez, Emmanuel Geneste, Patrick Pardon, Marie-Hélène Dévier, Hélène Budzinski
The occurrence and spatial distribution of 22 selected perfluoroalkyl and polyfluoroalkyl substances (PFASs) in surface water (n=75), groundwater (n=80) and surficial sediment (n=15) were investigated for the first time in the tropical areas constituted by the French Overseas Territories (French Guiana, Guadeloupe, Martinique, Mayotte and Reunion). Descriptive statistics and correlations between PFASs were evaluated through the use of specific statistical treatments to handle left-censored data ("non-detects")...
December 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28659453/human-impacts-reduce-morphological-diversity-in-an-insular-species-of-lizard
#17
Corentin Bochaton, Salvador Bailon, Anthony Herrel, Sandrine Grouard, Ivan Ineich, Anne Tresset, Raphaël Cornette
Fossil remains provide useful insights into the long-term impact of anthropogenic phenomena on faunas and are often used to reveal the local (extirpations) or global (extinctions) losses of populations or species. However, other phenomena such as minor morphological changes can remain inconspicuous in the fossil record depending on the methodology used. In this study, we used the anole of Marie-Galante Island (Anolis ferreus) in Guadeloupe (French, West Indies) as a model to demonstrate how the morphological evolution of an insular lizard can be tracked through the Pleistocene/Holocene climatic transition and the recent anthropization of the island...
June 28, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28624921/lung-adenocarcinoma-survival-in-egfr-mutated-african-caribbean-patients-a-multicenter-study-in-the-french-west-indies
#18
Nicolas Leduc, Vincent Atallah, Moustapha Agossou, Vincent Vinh-Hung, Mathieu Orre, Paul Sargos, Vincent Molinie
BACKGROUND: Lung cancer is the leading cause of cancer-related death worldwide. Shorter survival has been repeatedly reported for patients of African ancestry. Multivariate analysis demonstrated that this gap could be a consequence of socio-economic disparities instead of genetic specificities. However, those results were obtained in a pre-targeted therapies era and the effect of tyrosine kinase inhibitors targeting EGFR are not known in this population. OBJECTIVE: In this French West Indies study, we report overall survival (OS) in a frequently mutated population treated for lung adenocarcinoma within an equal-access healthcare system...
October 2017: Targeted Oncology
https://www.readbyqxmd.com/read/28610787/spolsimilaritysearch-a-web-tool-to-compare-and-search-similarities-between-spoligotypes-of-mycobacterium-tuberculosis-complex
#19
David Couvin, Thierry Zozio, Nalin Rastogi
Spoligotyping is one of the most commonly used polymerase chain reaction (PCR)-based methods for identification and study of genetic diversity of Mycobacterium tuberculosis complex (MTBC). Despite its known limitations if used alone, the methodology is particularly useful when used in combination with other methods such as mycobacterial interspersed repetitive units - variable number of tandem DNA repeats (MIRU-VNTRs). At a worldwide scale, spoligotyping has allowed identification of information on 103,856 MTBC isolates (corresponding to 98049 clustered strains plus 5807 unique isolates from 169 countries of patient origin) contained within the SITVIT2 proprietary database of the Institut Pasteur de la Guadeloupe...
July 2017: Tuberculosis
https://www.readbyqxmd.com/read/28543620/squamous-cell-carcinoma-in-the-afro-caribbean-community-an-11-year-retrospective-study
#20
N Cordel, L Bonnecarrère, B Tressières
BACKGROUND: Squamous cell carcinoma (SCC) is considered the most frequent skin cancer in Black people. Its incidence is not known in the Afro-Caribbean population. OBJECTIVE: To assess the incidence of SCC in Guadeloupe, the largest island of the Lesser Antilles (405 000 inhabitants, mostly Black people of African and European descent). The second objective was to characterize clinical and histological patterns of SCC occurring in the Afro-Caribbean community. METHODS: This retrospective study was conducted over an 11-year period (2000-2010)...
May 22, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
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