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https://www.readbyqxmd.com/read/29692295/outbreak-of-chikungunya-in-the-french-caribbean-islands-of-martinique-and-guadeloupe-findings-from-a-hospital-based-surveillance-system-2013-2015
#1
Frédérique Dorléans, Bruno Hoen, Fatiha Najioullah, Cécile Herrmann-Storck, Kinda Maria Schepers, Sylvie Abel, Isabelle Lamaury, Laurence Fagour, Raymond Césaire, Stéphanie Guyomard, Ruth Troudard, Yvette Adélaïde, Marie-José Romagne, Magguy Davidas, Séverine Rochais, Sylvie Boa, Frédérique de Saint-Alary, Annabel Preira, Patrick Saint-Martin, Amandine Vaidie, Mathilde Melin, Elise Daudens-Vaysse, Jacques Rosine, Alain Blateau, Luisiane Carvalho, Alexandra Septfons, Marie-Claire Paty, Ghislain Leduc, Sylvie Cassadou, Martine Ledrans, André Cabié
Chikungunya virus (CHIKV) emerged in the Caribbean island of Saint-Martin in December 2013. We implemented a hospital-based surveillance system to detect and describe CHIKV cases including severe forms of the infection and deaths in the islands of Martinique and Guadeloupe. A case was defined as a patient with a CHIKV laboratory confirmation cared for in a public hospital for chikungunya for at least 24 hours, and a severe CHIKV case was defined as a CHIKV case presenting one or more organ failures. Sociodemographic, clinical, and laboratory data were collected and cases classified into severe or nonsevere based on medical records...
April 23, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29685006/spoligotyping-analysis-of-mycobacterium-tuberculosis-with-tb-sprint-technology
#2
S Ali, C Sola, M Harrison, M Tahir, A Sheed Khan, M Mumtaz, E Chimara, F Hassan
Spoligotyping is a highly reproducible, fast polymerase chain reaction (PCR)-based approach for identification of different strains of Mycobacterium tuberculosis through genotyping of Mycobacterium tuberculosis complex (MTB). Molecular typing of MTB is helpful for understanding and controlling TB epidemics. Spoligotyping was performed on 166 strains of MTB collected from 25 districts of Khyber Pakhtunkhwa, Pakistan. Results were analyzed using online database, SITVIT2, developed by the Institute Pasteur de Guadeloupe, France and SPSS software V...
March 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29674916/occurrence-of-the-large-ostracod-chlamydotheca-unispinosa-baird-1862-in-temporary-waters-of-montserrat-lesser-antilles
#3
Robert E Schmidt, Nathaniel F Shoobs, Erin R McMullin
Four populations of the large freshwater ostracod, Chlamydotheca unispinosa (Baird, 1862), were discovered on the Caribbean island of Montserrat. These are the first records of the species on Montserrat and extend its known distribution approximately 113 km northwest and 63 km southeast of the closest known populations on Îles des Saintes (Guadeloupe) and Nevis, respectively. We provide the first DNA barcode for C. unispinosa , a 686 bp fragment of the COI gene which may be used for future comparative studies of this widely distributed species...
2018: ZooKeys
https://www.readbyqxmd.com/read/29621911/incidence-and-natural-history-of-preeclampsia-eclampsia-at-the-university-maternity-of-antananarivo-madagascar-high-prevalence-of-the-early-onset-condition
#4
Andriamanetsiarivo Tanjona Ratsiatosika, Eric Razafimanantsoa, Valéry Bruno Andriantoky, Noël Ravoavison, Rakotovao Andrianampanalinarivo Hery, Malik Boukerrou, Silvia Iacobelli, Pierre-Yves Robillard
OBJECTIVES: To investigate the incidence of early - (delivery < 34 weeks) (EOP) versus late-onset (delivery ≥ 34 weeks) (LOP) in Madagascar. STUDY DESIGN: Eight months observational study of all preeclamptic/eclamptic women delivering at the maternity of the University Hospital of Befelatanana, Antananarivo, Madagascar. Sociodemographical and obstetrical risk factors are analysed. RESULTS: Over the study period, we found 142 combined preeclampsia/eclampsia among 4316 births (incidence 3...
April 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29566237/allelic-variation-in-a-single-genomic-region-alters-the-microbiome-of-the-snail-biomphalaria-glabrata
#5
Euan R O Allan, Jacob A Tennessen, Thomas J Sharpton, Michael S Blouin
Freshwater snails are the intermediate hosts for numerous parasitic worms which can have negative consequences for human health and agriculture. Understanding the transmission of these diseases requires a more complete characterization of the immunobiology of snail hosts. This includes the characterization of its microbiome and genetic factors which may interact with this important commensal community. Allelic variation in the Guadeloupe Resistance Complex (GRC) genomic region of Guadeloupean Biomphalaria glabrata influences their susceptibility to schistosome infection, and may have other roles in the snail immune response...
March 16, 2018: Journal of Heredity
https://www.readbyqxmd.com/read/29525296/further-evidence-for-a-distinctive-atypical-degenerative-parkinsonism-in-the-caribbean-a-new-cluster-in-the-french-west-indian-island-of-martinique
#6
Annie Lannuzel, Régine Edragas, Angéla Lackmy, Benoit Tressières, Véronique Pelonde, Mireille Edimo Nana Kaptué, Sylvie Mécharles, Alexis Demas, Billy François, Eavan McGovern, Marie Vidailhet, Bertrand Gaymard, Emmanuel Roze
BACKGROUND: A high prevalence of an atypical levodopa-resistant parkinsonism has been reported in the Caribbean island of Guadeloupe. These seminal observations have not been replicated or extended to neighbouring populations who share genetic and environmental characteristics. METHODS: To further characterise this atypical parkinsonism we prospectively investigated 305 consecutive patients with neurodegenerative parkinsonism in a community-based population from Guadeloupe and Martinique, a neighbouring French Caribbean island where the population has similar environmental and genetic backgrounds...
May 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29477278/-initiation-of-first-dialysis-and-three-months-quality-of-life-of-patients-with-end-stage-renal-disease-in-the-french-territories-of-guadeloupe-and-guyane
#7
Jacqueline Deloumeaux, Gaël Samut, Devi Rochemont, Henri Merault, Roger Dufresne, Valérie Galantine, Yannick Tirolien, Catherine Léonardi, Antoine Adenis, Jessica Peruvien, Mathieu Nacher, Jean-Marc Gabriel
End stage renal disease is a major public health problem in the French Departments of Guadeloupe and Guiana because of the high prevalence of both type 2 diabetes and hypertension. We investigated factors associated with an emergency start of dialysis, 3 months' quality of life for patients starting a first replacement therapy in Guadeloupe and French Guiana using the data of the Réseau épidémiologie et information en néphrologie network, completed with data from the quality of life questionnaires SF-36 and KDQoL...
February 21, 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29449664/incidence-and-clinical-characteristics-of-ciguatera-fish-poisoning-in-guadeloupe-french-west-indies-between-2013-and-2016-a-retrospective-cases-series
#8
Denis Boucaud-Maitre, Jean-Paul Vernoux, Stéphane Pelczar, Elise Daudens-Vaysse, Lyderic Aubert, Sylvie Boa, Serge Ferracci, Robert Garnier
This retrospective case study analysed the incidence and symptoms of ciguatera fish poisoning (ciguatera) in Guadeloupe (French West Indies) between 2013 and 2016. Cases attending the emergency departments of the two public hospitals and the reports received by the regional health authority in charge of monitoring (ARS) were compiled. Two hundred and thirty-four cases of poisoning were observed, with a mean annual incidence of 1.47/10,000 (95% CI): 1.29-1.66), i.e 5 times higher than the previously reported incidence (1996-2006)...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29314392/using-isotopic-spike-from-tropical-storm-to-understand-water-exchange-on-large-scale-case-study-of-hurricane-rafael-in-the-lesser-antilles-archipelago-october-2012
#9
Luc Lambs, Félix Bompy, Maguy Dulormne
RATIONALE: Studies of wetland eco-hydrology in tropical coastal area are scarce, and the use of water stable isotopes can be of great help. Key constraints for their analysis are (i) the small difference in δ18 O values between seawater and old evaporated freshwater, and (ii) the fact that the presence of old brackish water limits the determination of the water origin and dynamic. METHODS: The water of tropical storms displays distinctively depleted heavy stable isotopes, in comparison with usual tropical rainfall without strong convective thunderstorms...
January 3, 2018: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29216354/high-prevalence-of-rare-monogenic-forms-of-obesity-in-obese-guadeloupean-afro-caribbean-children
#10
Lydia Foucan, Laurent Larifla, Emmanuelle Durand, Christine Rambhojan, Christophe Armand, Carl-Thony Michel, Rachel Billy, Véronique Dhennin, Franck De Graeve, Iandry Rabearivelo, Olivier Sand, Jean-Marc Lacorte, Philippe Froguel, Amélie Bonnefond
Context: The population of Guadeloupe Island exhibits a high prevalence of obesity. Objective: We aimed to investigate whether rare genetic mutations in genes involved in monogenic obesity (or diabetes) might be causal in this population of Afro-Caribbean ancestry. Design and Setting: This was a secondary analysis of a study on obesity conducted in schoolchildren from Guadeloupe in 2013 that aimed to assess changes in children's profiles after a lifestyle intervention program...
February 1, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29183229/prevalence-of-sickle-cell-disease-among-grenadian-newborns
#11
Magdalene Antoine, Ketty Lee, Tyhiesia Donald, Yonni Belfon, Ali Drigo, Sharon Polson, Francis Martin, George Mitchell, Maryse Etienne-Julan, Marie-Dominique Hardy-Dessources
Objective To establish the birth prevalence of sickle cell disease in Grenada, with a view to assess the requirement for a population-based neonatal screening programme. Methods A two-year pilot neonatal screening programme, involving the Ministry of Health of Grenada, the Sickle Cell Association of Grenada, and the diagnostic laboratory of hemoglobinopathies of the University Hospital of Guadeloupe, was implemented in 2014-2015 under the auspices of the Caribbean Network of Researchers on Sickle Cell Disease and Thalassemia...
March 2018: Journal of Medical Screening
https://www.readbyqxmd.com/read/29162379/-epidemiology-of-urolithiasis-in-french-west-indies-a-retrospective-study
#12
K Kaulanjan, A Cerruti, V Galantine, C Laine, J Rose Dite Modestine, G Gourtaud, C Senechal, V Roux, R Eyraud, P Blanchet, L Brureau
INTRODUCTION: The incidence of urolithiasis is increasing with dietary changes especially in developed countries. Guadeloupe is a French department overseas where western diet meets traditional local food. The objective was to describe and analyze the epidemiology of urolithiasis in Guadeloupe. MATERIAL AND METHODS: We conducted a retrospective single-center study throughout the year 2015 on patients hospitalized for urolithiasis at University Hospital of Pointe-à-Pitre...
February 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29137971/clearance-of-schistosome-parasites-by-resistant-genotypes-at-a-single-genomic-region-in-biomphalaria-glabrata-snails-involves-cellular-components-of-the-hemolymph
#13
Euan R O Allan, Benjamin Gourbal, Camila B Dores, Anais Portet, Christopher J Bayne, Michael S Blouin
Schistosomiasis is one of the most detrimental neglected tropical diseases. Controlling the spread of this parasitic illness requires effective sanitation, access to chemotherapeutic drugs, and control over populations of the freshwater snails, such as Biomphalaria glabrata, that are essential intermediate hosts for schistosomes. Effectively controlling this disease, while minimising ecological implications of such control, will require an extensive understanding of the immunological interactions between schistosomes and their molluscan intermediate hosts...
November 12, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/29121918/-no-generics-doctor-the-perspective-of-general-practitioners-in-two-french-regions
#14
Béatrice Riner, Adèle Bussy, Jeannie Hélène-Pelage, Nycrees Moueza, Sébastien Lamy, Philippe Carrère
BACKGROUND: Generic medicines are essential to controlling health expenditures. Their market share is still small in France. The discourse and practices of prescribers may play a major role in their use. The purpose of this study was to explore the knowledge, attitudes and practices of general practitioners (GPs) toward generic medicines in two French regions with the lowest penetration rate of these products. METHODS: An observational study was carried out from October 2015 to February 2016 in Guadeloupe and Martinique...
November 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29120835/characteristics-of-invasive-breast-cancer-and-overall-survival-of-patients-eligible-for-mass-breast-cancer-screening-in-guadeloupe-compared-to-those-of-the-preceding-age-group
#15
Philippe Kadhel, Daphné Borja De Mozota, Stéphanie Gaumond, Jacqueline Deloumeaux
BACKGROUND: Mass breast cancer screening is offered to French women between the ages of 50 and 74. In the French overseas department of Guadeloupe, where the population is of mostly African ancestry, a low age at diagnosis of breast cancer has been reported, as for African-Americans. This raises the question of whether breast cancer is more aggressive in the age group preceding that eligible for mass screening (40-49) in Guadeloupe. METHODS: We compared the tumor-related prognostic factors, first line therapy and overall survival rates of breast cancer cases diagnosed between the 40-49 and 50-74 age groups, based on reports of the cancer registry of Guadeloupe for the period 2008-2013...
October 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/29118595/a-taxonomic-review-of-the-selenophori-group-coleoptera-carabidae-harpalini-in-the-west-indies-with-descriptions-of-new-species-and-notes-about-classification-and-biogeography
#16
Danny Shpeley, Wesley Hunting, George E Ball
Primarily a taxonomic review of the West Indian elements of the selenophorine Harpalini, this paper includes a classification, a key, descriptions and illustrations of taxa, re-rankings, and new synonymies. In total, 45 species and subspecies are treated, six of which are described as new. A new genus and new species are as follows, with type localities in parentheses: Paraulacoryssus gen. n. , (type species Selenophorus puertoricensis Mutchler, 1934); Neodiachipteryx davidsoni sp. n. , (Zamba, Dominican Republic); Selenophorus spinosus sp...
2017: ZooKeys
https://www.readbyqxmd.com/read/29107743/allelic-variation-partially-regulates-galactose-dependent-hydrogen-peroxide-release-from-circulating-hemocytes-of-the-snail-biomphalaria-glabrata
#17
Euan R O Allan, Michael S Blouin
Freshwater snails are the intermediate hosts for numerous parasitic worms that are detrimental to human and agricultural health. Understanding the immune responses of these snails could be vital for finding ways to block transmission of those parasites. Allelic variation in a recently discovered genomic region in the snail, Biomphalaria glabrata, influences their susceptibility to schistosomes. Here we tested whether genes in that region, termed the Guadeloupe Resistance Complex (GRC), are involved in recognition of common pathogen-associated molecules that have been shown to be stimulants of the hydrogen peroxide defense pathway...
January 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29053358/bioinvasion-triggers-rapid-evolution-of-life-histories-in-freshwater-snails
#18
Elodie Chapuis, Thomas Lamy, Jean-Pierre Pointier, Nicolas Juillet, Adeline Ségard, Philippe Jarne, Patrice David
Biological invasions offer interesting situations for observing how novel interactions between closely related, formerly allopatric species may trigger phenotypic evolution in situ. Assuming that successful invaders are usually filtered to be competitively dominant, invasive and native species may follow different trajectories. Natives may evolve traits that minimize the negative impact of competition, while trait shifts in invasives should mostly reflect expansion dynamics, through selection for colonization ability and transiently enhanced mutation load at the colonization front...
November 2017: American Naturalist
https://www.readbyqxmd.com/read/28921374/prostate-cancer-clinical-presentation-incidence-mortality-and-survival-in-guadeloupe-over-the-period-2008-2013-from-a-population-based-cancer-registry
#19
J Deloumeaux, B Bhakkan, R Eyraud, F Braud, N Manip M'Ebobisse, P Blanchet, L Brureau
PURPOSE: The Caribbean population of Guadeloupe has one of the highest incidence rates of prostate cancer worldwide. In 2008, a population-based cancer registry was set up for the monitoring of cancer incidence in the aftermath of the environmental pollution with chlordecone, a persistent organochlorine insecticide formerly used in banana plantations. We describe the clinical presentation, incidence, mortality and survival of prostate cancer for the period 2008-2013. METHODS: The Guadeloupe cancer registry has been routinely collecting all incident cases of cancer since 2008...
November 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28838639/effect-of-acute-zika-virus-infection-on-sperm-and-virus-clearance-in-body-fluids-a-prospective-observational-study
#20
Guillaume Joguet, Jean-Michel Mansuy, Giulia Matusali, Safouane Hamdi, Marie Walschaerts, Lynda Pavili, Stefanie Guyomard, Nadia Prisant, Pierre Lamarre, Nathalie Dejucq-Rainsford, Christophe Pasquier, Louis Bujan
BACKGROUND: Evidence of human sexual transmission during Zika virus emergence is a matter of concern, particularly in procreation, but to date, kinetics of seminal shedding and the effects of infection on human reproductive function have not been described. To investigate the effects of Zika virus infection on semen and clearance of Zika virus from semen and body fluids, we aimed to study a cohort of Zika virus-infected men. METHODS: This prospective observational study recruited men presenting with acute Zika virus infection at Pointe-à-Pitre University Hospital in Guadeloupe, French Caribbean, where a Zika virus outbreak occurred between April and November, 2016...
November 2017: Lancet Infectious Diseases
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