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https://www.readbyqxmd.com/read/28642654/quantitative-evaluation-of-experimental-bone-regeneration-using-indentation-tests
#1
Valéria Trombini Vidotto, Nilza Alzira Batista, José Ricardo Lenzi Mariolani, William Dias Belangero
OBJECTIVES: To determine whether the macroindentation test can be applied to quantitatively assess bone regeneration. METHODS: A 3.2 mm diameter transverse monocortical defect was created on the medial aspect of both proximal metaphyses of the tibia of male Unib-WH rats. For the macroindentation tests, we used 5.00 mm diameter indenters with a 3.2 mm tip. Defect testing was performed 1 to 12 weeks following the surgical procedures to compare the hardness of the newly developed tissue over the 12-week study period...
March 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28598950/drill-induced-cochlear-injury-during-otologic-surgery-intracochlear-pressure-evidence-of-acoustic-trauma
#2
Renee M Banakis Hartl, Jameson K Mattingly, Nathaniel T Greene, Nyssa F Farrell, Samuel P Gubbels, Daniel J Tollin
HYPOTHESIS: Drilling on the incus produces intracochlear pressure changes comparable to pressures created by high-intensity acoustic stimuli. BACKGROUND: New-onset sensorineural hearing loss (SNHL) following mastoid surgery can occur secondary to inadvertent drilling on the ossicular chain. To investigate this, we test the hypothesis that high sound pressure levels are generated when a high-speed drill contacts the incus. METHODS: Human cadaveric heads underwent mastoidectomy, and fiber-optic sensors were placed in scala tympani and vestibuli to measure intracochlear pressures (PIC)...
June 8, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28584936/a-review-of-nitric-oxide-for-the-treatment-of-glaucomatous-disease
#3
REVIEW
Joah Aliancy, W Daniel Stamer, Barbara Wirostko
Glaucoma is the leading cause of irreversible blindness worldwide, affecting 64.3 million people. An estimated 60.5 million people are affected by primary open angle glaucoma globally, and this will increase to 111.8 million by 2040. The definition of glaucoma has evolved greatly over time. Although multiple risk factors such as ischemia, inflammation, myopia, race, age and low ocular perfusion pressure may play a role, intraocular pressure (IOP) is still the main risk factor we can easily identify and modify...
June 5, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28571226/optic-nerve-canal-relation-to-posterior-paranasal-sinuses-in-indian-ethnics-review-and-objective-classification
#4
Rishikesh Madhukar Itagi, Chaitra Parameshwara Adiga, Kiran Kalenahalli, Lakshmikanth Goolahally, Manju Gyanchandani
INTRODUCTION: Posterior paranasal sinuses consisting of posterior ethmoid and sphenoid sinuses show varying pneumatization and relationship to Optic Nerve Canal (ONC). Most commonly ONC is superolateral to sphenoid sinus, however varied protrusion of ONC into the sinuses may occur. Rarely it may pass completely through the sinus. Optic Nerve (ON) is covered by a thin bony layer or by periosteum and sinus mucosa without bone. Extensive pneumatization of sphenoid sinus and bony dehiscence predisposes to ON injury...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28570420/semicircular-canal-pressure-changes-during-high-intensity-acoustic-stimulation
#5
Anne K Maxwell, Renee M Banakis Hartl, Nathaniel T Greene, Victor Benichoux, Jameson K Mattingly, Stephen P Cass, Daniel J Tollin
HYPOTHESIS: Acoustic stimulation generates measurable sound pressure levels in the semicircular canals. BACKGROUND: High-intensity acoustic stimuli can cause hearing loss and balance disruptions. To examine the propagation of acoustic stimuli to the vestibular end-organs, we simultaneously measured fluid pressure in the cochlea and semicircular canals during both air- and bone-conducted sound presentation. METHODS: Five full-cephalic human cadaveric heads were prepared bilaterally with a mastoidectomy and extended facial recess...
May 31, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28538978/the-characteristics-of-deep-optic-nerve-head-morphology-in-myopic-normal-tension-glaucoma
#6
Jong Chul Han, Eun Jung Lee, Si Bum Kim, Changwon Kee
Purpose: To investigate the relationship between axial length (AL) and deep optic nerve head (ONH) structure and to evaluate the characteristics of deep ONH structures in myopic normal tension glaucoma (NTG). Methods: The following parameters were assessed using spectral-domain optical coherence tomography (SD-OCT): externally oblique border tissue (EOBT) length, ONH tilt angle, optic canal (OC) obliqueness, and β-zone peripapillary atrophy (PPA). In addition, the angular location of the maximal value of each parameter and retinal nerve fiber layer (RNFL) defect were measured using infrared and red-free photos...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28527685/optic-canal-decompression-a-comparison-of-two-surgical-techniques
#7
Paulo Moacir Mesquita, Daniel M Prevedello, Luciano Prevedello, Leo F Ditzel Filho, Mariano E Fiore, Ricardo L Dolci, Lamia Buohliqah, Bradley A Otto, Ricardo Carrau
No abstract text is available yet for this article.
May 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28527594/whole-globe-biomechanics-using-high-field-mri
#8
Andrew P Voorhees, Leon C Ho, Ning-Jiun Jan, Huong Tran, Yolandi van der Merwe, Kevin Chan, Ian A Sigal
The eye is a complex structure composed of several interconnected tissues acting together, across the whole globe, to resist deformation due to intraocular pressure (IOP). However, most work in the ocular biomechanics field only examines the response to IOP over smaller regions of the eye. We used high-field MRI to measure IOP induced ocular displacements and deformations over the whole globe. Seven sheep eyes were obtained from a local abattoir and imaged within 48 h using MRI at multiple levels of IOP. IOP was controlled with a gravity perfusion system and a cannula inserted into the anterior chamber...
May 17, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28526645/carotid-falciform-optic-neuropathy-microsurgical-treatment
#9
M Neil Woodall, Cargill H Alleyne
BACKGROUND: Several recent reports have implicated vascular ectasia and vessel contact with dysfunction of the visual apparatus. A subset of patients with pre-chiasmatic visual deterioration have an ectatic internal carotid artery (ICA) that displaces and flattens the optic nerve (ON) rostrally as the ON exits the skull base. We will offer a proposed pathophysiological mechanism and describe a straightforward surgical technique for dealing with this interesting problem. METHODS: Via an ipsilateral pterional craniotomy, the bony roof of the optic canal is removed...
May 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28516966/expanded-transcanal-transpromontorial-approach-to-the-internal-auditory-canal-and-cerebellopontine-angle-a-cadaveric-study
#10
L Presutti, M Bonali, D Marchioni, G Pavesi, A Feletti, L Anschuetz, M Alicandri-Ciufelli
The aim of this paper is to describe and evaluate the feasibility of an expanded endoscopic transcanal transpromotorial approach (ExpTTA) to the internal auditory canal and the cerebellopontine angle. To this end, we performed a cadaveric dissection study in September 2015. In total, 2 heads (4 sides) were dissected focusing on anatomical landmarks and surgical feasibility. Data from dissections were reviewed and analysed for further consideration. In all 4 sides of the cadavers the procedure was feasible. In all cadavers, it was necessary to extensively drill the temporo-mandibular joint and to calibrate the external ear canal to allow adequate room to manoeuver the instruments and optics and to comfortably access the cerebellopontine angle...
June 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28483236/the-prevalence-of-the-onodi-cell-most-suitable-method-of-ct-evaluation-in-its-detection
#11
L P Chmielik, A Chmielik
BACKGROUND: The Onodi cell (sphenoethmoidal air cell) is an anatomic variant of the most posterior ethmoid cell that pneumatised superiorly and laterally to the sphenoid sinus, and is in close relation to the optic nerve. The proper identification of the Onodi cell is essential during a pre-operative computer tomography (CT) examination, as the presence of that ethmoid cell variant makes sphenoid sinus surgery more risky. The bulging of the optic nerve to the ethmoid cell wall is well visualized during endoscopic examination, but there are no clearly defined criteria for a potentially dangerous Onodi cell type in CT examinations...
June 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28474186/sphenoorbital-meningioma-surgical-series-and-design-of-an-intraoperative-management-algorithm
#12
Lior Gonen, Eytan Nov, Nir Shimony, Ben Shofty, Nevo Margalit
Current surgical removal of sphenoorbital meningiomas (SOM) mainly aims at reduction of proptosis and restoration of visual function; some stages of the surgical technique are controversial. In this study, we aim to present a surgical decision-making algorithm for SOM. A retrospective study of 27 patients who underwent resection of SOM in our center (2005-2014) was conducted. The primary outcomes evaluated were postoperative visual function and radiological exophthalmos. In our study, clinical proptosis was the most common presenting sign (92%), followed by visual loss (37%)...
May 4, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28455115/reduced-free-communication-of-the-subarachnoid-space-within-the-optic-canal-in-the-human
#13
Mikee Liugan, Zhaoyang Xu, Ming Zhang
PURPOSE: Recent studies in patients demonstrated that cerebrospinal fluid does not flow continuously between the intracranial subarachnoid space (SAS) and the space around the optic nerve in the orbit. Its anatomical basis remains elusive. The objective of this study was to use a novel anatomical technology, the epoxy sheet plastination, to reveal the configuration of the fibrous structures within the optic canal and their relationship with the optic nerve, SAS and ophthalmic artery. DESIGN: A human cadaveric study...
April 25, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28440591/imaging-collector-channel-entrance-with-a-new-intraocular-micro-probe-swept-source-optical-coherence-tomography
#14
Chen Xin, Xiaoya Chen, Meng Li, Yan Shi, Huaizhou Wang, Ruikang Wang, Ningli Wang
PURPOSE: To describe the use of a newly developed side-viewing catheter probe to provide the cross-sectional images of collector channel entrance (CCE), achieved by swept-source optical coherence tomography (SS-OCT). METHODS: A side-viewing SS-OCT catheter probe was developed that has a core probe diameter of 0.15 mm and an outer diameter of 0.25 mm, for the purpose of imaging CCEs within eye globe. Cadaver eyes harvested from swine and human were used to demonstrate its feasibility...
April 25, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28437265/unilateral-blindness-after-septoplasty
#15
Ahmet Erdem Kilavuz, Duzgun Yildirim, Gediz Murat Serin, Asim Kaytaz
Septoplasty is a frequently performed procedure with mostly minor complications. Nevertheless, it may lead to serious complications.The authors present a 29-year-old patient admitted to their hospital 10 days after septoplasty in another institution. He suffered a total loss of vision immediately after the surgery.High-resolution computed tomography and magnetic resonance imaging revealed a direct trauma of the optic canal and an inflamed and edematous optic nerve. Even though a successful endoscopic optic nerve was performed, the patient's loss of vision did not improve after the surgery...
April 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28435366/comparative-evaluation-of-antimicrobial-efficacy-of-triple-antibiotic-paste-calcium-hydroxide-and-a-proton-pump-inhibitor-against-resistant-root-canal-pathogens
#16
Shibha Mehta, Promila Verma, Aseem Prakash Tikku, Anil Chandra, Rhythm Bains, Gopa Banerjee
OBJECTIVE: The objective of this study is to compare the antimicrobial efficacy of triple antibiotic paste (TAP) and a proton pump inhibitor (PPI) (omeprazole) in combination with calcium hydroxide (CH) against Enterococcus faecalis and Candida albicans. MATERIALS AND METHODS: E. faecalis and C. albicans were subcultured and inoculated at 37° overnight and were treated with different dilutions of TAP, 25 μg/ml (Group 1), CH (Group 2, control), CH 16 mg/ml + omeprazole 2 mg/ml (Group 3a) (CH 16 mg/ml + omeprazole 4 mg)/ml (Group 3b) for 24, 48, and 72 h in sterile uncoated 96-well microtiter plates...
January 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28416309/detection-of-apical-root-cracks-using-spectral-domain-and-swept-source-optical-coherence-tomography
#17
Bruna Paloma de Oliveira, Andréa Cruz Câmara, Daniel Amancio Duarte, Anderson Stevens Leonidas Gomes, Richard John Heck, Antonio Celso Dantas Antonino, Carlos Menezes Aguiar
INTRODUCTION: This study aimed to evaluate the ability of 2 optical coherence tomographic (OCT) systems to detect apical dentinal microcracks. METHODS: Twenty extracted human single-rooted mandibular incisors were selected. After root canal preparation with an R40 Reciproc file (VDW, Munich, Germany), the specimens presenting apical microcracks were identified using micro-computed tomographic (micro-CT) scanning as the gold standard. Then, the apical portions of the roots were imaged with spectral domain OCT (SD-OCT) and swept-source OCT systems, and the resulting images were blindly evaluated by 3 independent examiners to detect microcracks...
April 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28413768/surgical-resection-of-an-optic-nerve-sheath-meningioma-relevance-of-endoscopic-endonasal-approaches-to-the-optic-canal
#18
Patrick J Hunt, Franco DeMonte, Rosa A Tang, Shirley Y Su, Shaan M Raza
Optic nerve sheath meningiomas (ONSMs) account for less than 2% of meningiomas and 1.7% of orbital tumors. Although rare, the management of these tumors is important as unilateral blindness often results in untreated cases. Radiotherapy has emerged as the preferred treatment. However, therapies for ONSMs are controversial due to the variable natural history of the disease and limitations of surgical and radiotherapy options. A 60-year-old woman presented with monocular left diminished color perception and blurred vision...
April 2017: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/28405489/three-dimensional-optical-coherence-tomography-imaging-and-treatment-of-glaucomatous-optic-nerve-head-defects-associated-with-schisis-like-maculopathy
#19
Zafer Öztaş, Jale Menteş, Halil Ateş, Serhad Nalçacı
We present the three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) findings of schisis-like maculopathy associated with structural changes of the optic nerve (ON) head as well as the treatment outcomes of a case of advanced glaucoma. In addition to ophthalmological examination, B-scan and 3D-SD-OCT images of the ON head, peripapillary retina, and the macula were obtained. The B-scan images only detected typical retinoschisis findings. However, the 3D-SD-OCT images of the ON head revealed defects of various sizes, shapes, and depths at the outer wall of the prelaminar and laminar regions of the ON canal...
April 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28388344/the-revised-anatomy-of-the-canals-connecting-the-orbit-with-the-cranial-cavity
#20
Marì Regoli, Eugenio Bertelli
Orbits are connected with the middle cranial fossa via the optic canal, the superior orbital fissure, the M-type orbitomeningeal foramen, the metoptic canal, an accessory anterior opening of the foramen rotundum, and Warwick's canal. They are also in communication with the anterior cranial fossa via the ethmoidal canals and the A-type orbitomeningeal foramen. The anatomy of these conduits has been recently enriched with several details that are summarized and reviewed in this article.
April 2017: Orbit
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