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Adolescent + idiopathic + scoliosis

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https://www.readbyqxmd.com/read/28428982/biomechanical-effect-of-pedicle-screw-distribution-in-ais-instrumentation-using-a-segmental-translation-technique-computer-modeling-and-simulation
#1
Xiaoyu Wang, A Noelle Larson, Dennis G Crandall, Stefan Parent, Hubert Labelle, Charles G T Ledonio, Carl-Eric Aubin
BACKGROUND: Efforts to select the appropriate number of implants in adolescent idiopathic scoliosis (AIS) instrumentation are hampered by a lack of biomechanical studies. The objective was to biomechanically evaluate screw density at different regions in the curve for AIS correction to test the hypothesis that alternative screw patterns do not compromise anticipated correction in AIS when using a segmental translation technique. METHODS: Instrumentation simulations were computationally performed for 10 AIS cases...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28428081/intraoperative-image-guidance-compared-with-free-hand-methods-in-adolescent-idiopathic-scoliosis-posterior-spinal-surgery-a-systematic-review-on-screw-related-complications-and-breach-rates
#2
Andrew Chan, Eric Parent, Karl Narvacan, Cindy San, Edmond Lou
BACKGROUND CONTEXT: Severe adolescent idiopathic scoliosis (AIS) is a 3D spinal deformity requiring surgery to stop curve progression. Posterior spinal instrumentation and fusion with pedicle screws is the standard surgery for AIS curve correction. Vascular and neurologic complications related to screw-malpositioning are concerns in surgeries for AIS. Breach rates are reported at 15.7%, implant-related complications at 1.1% and neurologic deficit at 0.8%. Free-hand screw insertion remains the prevailing method of screw placement while image guidance has been suggested to improve placement accuracy...
April 17, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28418040/the-height-width-depth-ratios-of-the-intervertebral-discs-and-vertebral-bodies-in-adolescent-idiopathic-scoliosis-vs-controls-in-a-chinese-population
#3
Hao Chen, Tom P C Schlösser, Rob C Brink, Dino Colo, Marijn van Stralen, Lin Shi, Winnie C W Chu, Pheng-Ann Heng, René M Castelein, Jack C Y Cheng
Adolescent idiopathic scoliosis (AIS) patients have been reported to be taller and more slender than normal controls, suggesting less mechanical stiffness of their trunk and spine. For assessment of mechanical stiffness, to our best knowledge this is the first to study height-width-depth relations at the level of the individual vertebra and disc in 3-D and to evaluate its relation with the Cobb angle severity. A unique series of high-resolution pre-operative computed tomographic (CT) scans of a total of 105 Chinese patients with moderate to severe AIS and 11 age-matched non-scoliotic controls were used for this study...
April 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28414745/mapping-the-srs-22r-questionnaire-onto-the-eq-5d-5l-utility-score-in-patients-with-adolescent-idiopathic-scoliosis
#4
Carlos King Ho Wong, Prudence Wing Hang Cheung, Dino Samartzis, Keith Dip-Kei Luk, Kenneth M C Cheung, Cindy Lo Kuen Lam, Jason Pui Yin Cheung
This is a prospective study to establish prediction models that map the refined Scoliosis Research Society 22-item (SRS-22r) onto EuroQoL-5 dimension 5-level (EQ-5D-5L) utility scores in adolescent idiopathic scoliosis (AIS) patients. Comparison of treatment outcomes in AIS can be determined by cost-utility analysis. However, the mainstay spine-specific health-related quality of life outcome measure, the SRS-22r questionnaire does not provide utility assessment. In this study, AIS patients were prospectively recruited to complete both the EQ-5D-5L and SRS-22r questionnaires by trained interviewers...
2017: PloS One
https://www.readbyqxmd.com/read/28413830/an-observational-study-on-surgically-treated-adult-idiopathic-scoliosis-patients-quality-of-life-outcomes-at-1-and-2-year-follow-ups-and-comparison-to-controls
#5
Jennifer C Theis, Anna Grauers, Elias Diarbakerli, Panayiotis Savvides, Allan Abbott, Paul Gerdhem
BACKGROUND: Prospective data on health-related quality of life in patients with idiopathic scoliosis treated surgically as adults is needed. We compared preoperative and 1- and 2-year follow-up data in surgically treated adults with idiopathic scoliosis with juvenile or adolescent onset. Results were compared to untreated adults with scoliosis and population normative data. METHODS: A comparison of preoperative and 1- and 2-year follow-up data of 75 adults surgically treated for idiopathic scoliosis at a mean age of 28 years (range 18 to 69) from a prospective national register study, as well as a comparison with age- and sex-matched data from 75 untreated adults with less severe scoliosis and 75 adults without scoliosis, was made...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28405634/adolescents-with-idiopathic-scoliosis-and-their-parents-have-a-positive-attitude-towards-the-thermobrace-monitor-results-from-a-survey
#6
Sabrina Donzelli, Fabio Zaina, Gregorio Martinez, Francesca Di Felice, Alberto Negrini, Stefano Negrini
BACKGROUND: A temperature monitor is used to objectively measure brace wear time in adolescent idiopathic scoliosis. The reliability of this device have been demonstrated, and some specialists introduced the use of a compliance monitor as a standard of care in everyday clinical practice, as we did since 2010 with the Thermobrace (TB). The attitude towards these objective monitors has never been investigated. The present study aims to investigate the attitude of parents and patients towards the use of temperature sensors for measuring brace wear compliance...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28399556/incidence-of-pleural-fluid-and-its-associated-risk-factors-after-posterior-spinal-fusion-in-patients-with-adolescent-idiopathic-scoliosis
#7
Kazunori Hayashi, Hidetomi Terai, Hiromitsu Toyoda, Akinobu Suzuki, Masatoshi Hoshino, Koji Tamai, Shoichiro Ohyama, Hiroaki Nakamura
STUDY DESIGN: Retrospective review of prospectively-collected data. OBJECTIVE: To determine the incidence pleural fluid (PF) and its associated risk factors after posterior corrective spinal fusion (PCSF) in patients with adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA: Subclinical PF is often observed after PCSF in AIS patients. However, a few reports have been published regarding the incidence, characteristics, and associated risk factors...
April 15, 2017: Spine
https://www.readbyqxmd.com/read/28393345/-bracing-in-adolescent-idiopathic-scoliosis
#8
Yi-Fang Lo, Yu-Chu Huang
Scoliosis is a common medical problem, with an incidence of between 0.47% and 5.2% in the general population globally. Adolescent idiopathic scoliosis (AIS) accounts for nearly 80% of all scoliosis. Young people with AIS often experience negative social consequences in association with their condition. Without proper and timely treatment, the potential resulting disabilities range from trunk deformity, pain, and neurological complications to compromised cardiopulmonary function, all of which may cause lifelong suffering...
April 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/28389887/selective-versus-hyperselective-posterior-fusions-in-lenke-5-adolescent-idiopathic-scoliosis-comparison-of-radiological-and-clinical-outcomes
#9
B Ilharreborde, E Ferrero, A Angelliaume, Y Lefèvre, F Accadbled, A L Simon, J Sales de Gauzy, K Mazda
PURPOSE: Recent literature has reported that the ]progression risk of Lenke 5 adolescent idiopathic scoliosis (AIS) during adulthood had been underestimated. Surgery is, therefore, proposed more to young patients with progressive curves. However, choice of the approach and fusion levels remains controversial. The aim of this study was to analyze the influence of the length of posterior fusion on clinical and radiological outcomes in Lenke 5 AIS. METHODS: All Lenke 5 AIS operated between 2008 and 2012 were included with a minimum 2-year follow-up...
April 7, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28379517/convex-rod-derotation-maneuver-on-lenke-type-i-adolescent-idiopathic-scoliosis
#10
Huang Zifang, Fan Hengwei, Deng Yaolong, Sui Wenyuan, Wang Qifei, Cao Lei, Fobao Li, Yang Junlin
BACKGROUND: Convex-rod derotation may have potential advantages for adolescent idiopathic scoliosis (AIS) correction; however, study of this technique has been limited. OBJECTIVE: To compare the radiographic outcomes of Lenke type I AIS patients treated by the convex- or concave-rod derotation maneuvers. METHODS: A retrospective study was designed to compare 2 cohorts, including 81 Lenke type I AIS patients treated with convex-rod derotation (n = 38) or concave-rod derotation (n = 43), between July 2008 and September 2012...
April 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28376758/the-value-of-applying-a-melatonin-antagonist-luzindole-in-improving-the-success-rate-of-the-bipedal-rat-scoliosis-model
#11
Shuo Yang, Chaojun Zheng, Jianyuan Jiang, Feizhou Lu, Xinlei Xia, Wei Zhu, Xiang Jin, Xiaosheng Ma
BACKGROUND: An ideal animal model has always been the key to research the pathogenesis and treatment of adolescent idiopathic scoliosis (AIS), while available methods have obvious disadvantages. The deficiency of melatonin has been proved relating to AIS. In this research, we intended to apply Luzindole, the melatonin antagonist, in bipedal rat model, for the block of combination of melatonin and its receptor, to inhibit the melatonin effect, and then to understand whether this method can effectively improve the scoliosis rate of bipedal rat model, and investigate the role of melatonin in scoliosis...
April 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28374731/-the-spa-and-health-resort-based-treatment-of-back-pain-syndrome-in-the-adolescents-presenting-with-juvenile-idiopathic-scoliosis
#12
E Yu Kravtsova, S V Murav'ev, Yu I Kravtsov
The relevance of the problem arises from the lack of substantiation for the inclusion of transcutaneous spinal direct current stimulation (tSDCS) in the comprehensive spa and health resort-based treatment of back pain syndrome in the adolescents presenting with juvenile idiopathic scoliosis. AIM: The objective of the present study was to demonstrate the effectiveness of transcutaneous spinal direct current stimulation for the comprehensive spa and health resort-based treatment of back pain syndrome in the adolescents presenting with juvenile idiopathic scoliosis...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/28373082/five-major-controversial-issues-about-fusion-level-selection-in-corrective-surgery-for-adolescent-idiopathic-scoliosis-a-narrative-review
#13
REVIEW
Choon Sung Lee, Chang Ju Hwang, Dong-Ho Lee, Jae Hwan Cho
BACKGROUND CONTEXT: Shoulder imbalance, coronal decompensation, and adding-on phenomenon following corrective surgery in adolescent idiopathic scoliosis patients are known to be related to the fusion level selected. Although many studies have assessed the appropriate selection of the proximal and distal fusion level, no definite conclusions have been drawn thus far. PURPOSE: We aimed to assess the problems with fusion level selection for corrective surgery in patients with adolescent idiopathic scoliosis, and to enhance understanding about these problems...
March 31, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28355357/the-influence-of-body-image-on-surgical-decisions-in-adolescent-idiopathic-scoliosis-patients
#14
Paulo Alvim Borges, José Thomé de Carvalho, Olavo Biraghi Letaif, Raphael Martus Marcon, Alexandre Fogaça Cristante
OBJECTIVES: The objective of this study was to evaluate whether the severity of deformities in patients with adolescent idiopathic scoliosis contributes to patients' decision regarding whether to undergo an operation. METHODS: We evaluated body image factors in adolescent idiopathic scoliosis patients. We evaluated the magnitude of the main scoliotic curve, gibbosity (magnitude and location), shoulder height asymmetry and patient's age. We analyzed the correlation of these data with the number of years the patient was willing to trade for surgery, as measured by the time-trade-off method...
March 2017: Clinics
https://www.readbyqxmd.com/read/28349268/segmental-vs-non-segmental-thoracic-pedicle-screws-constructs-in-adolescent-idiopathic-scoliosis-is-there-any-implant-alloy-effect
#15
Mario Di Silvestre, Georgeous Bakaloudis, Carlo Ruosi, Valerio Pipola, Gianluca Colella, Tiziana Greggi, Alberto Ruffilli, Francesco Vommaro
PURPOSE: The aim of this study is to understand how many anchor sites are necessary to obtain maximum posterior correction of idiopathic scoliotic curve and if the alloy of instrumentation, stainless steel or titanium, may have a role in the percent of scoliosis correction. METHODS: We reviewed 143 consecutive patients, affected by AIS (Lenke 1-2), who underwent a posterior spinal fusion with pedicle screw-only instrumentation between 2002 and 2005. According to the implant density and alloy used we divided the cohort in four groups...
March 27, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28349022/evaluating-accuracy-of-free-hand-pedicle-screw-insertion-in-adolescent-idiopathic-scoliosis-using-postoperative-multi-slice-computed-tomography-scan
#16
Mohammadreza Etemadifar, Mohammadhossein Jamalaldini
BACKGROUND: Pedicle screw instrumentation has many advantages for correction of adolescent idiopathic scoliosis (AIS) deformity including better correction and fewer late complications. On the other hand, screw insertion in AIS is challenging. Intraoperative fluoroscopy or navigation techniques are expensive, time-consuming, and exposed to high radiation. Free-hand technique relies on the surgeon's experience and locating the pedicle entry point with anatomical landmarks. There are few studies that evaluated pedicle screw position accuracy with postoperative multi-slice computed tomography scan...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28346762/predicting-the-pain-continuum-after-adolescent-idiopathic-scoliosis-surgery-a-prospective-cohort-study
#17
V Chidambaran, L Ding, D L Moore, K Spruance, E M Cudilo, V Pilipenko, M Hossain, P Sturm, S Kashikar-Zuck, L J Martin, S Sadhasivam
BACKGROUND: Chronic postsurgical pain (CPSP) affects half a million children annually in the United States, with dire socioeconomic consequences, including long-term disability into adulthood. The few studies of CPSP in children are limited by sample size, follow-up duration, non-homogeneity of surgical procedure and factors evaluated. METHODS: In a prospective study of 144 adolescents undergoing a single major surgery (spine fusion), we evaluated demographic, perioperative, surgical and psychosocial factors as predictors of a continuum of postsurgical pain: immediate, pain maintenance at 2-3 months (chronic pain/CP) and persistence of pain a year (persistent pain/PP) after surgery...
March 27, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28344731/review-of-physical-activity-benefits-and-potential-considerations-for-individuals-with-surgical-fusion-of-spine-for-scoliosis
#18
EDITORIAL
Rumit Singh Kakar, Kathy J Simpson, Bhibha M DAS, Cathleen N Brown
Evidence-based recommendations for physical activity following spinal fusion surgeries for idiopathic scoliosis are limited, specifically in the adolescent population. Individuals with scoliosis treated operatively or non-operatively have been reported to participate in less than 1-3 days/week of even mildly strenuous physical exercises. Over 40% of individuals with scoliosis returned to sports at a level lower than pre-operative participation levels or did not return at all post spinal fusion. It is particularly important for human movement specialists, such as physical therapists, occupational therapists, athletic trainers and kinesiologists to assist these individuals effectively transition to and maintain engagement in physical activity...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28343332/posterior-elements-disruption-with-hybrid-constructs-in-ais-patients-is-there-an-impact-on-proximal-junctional-kyphosis
#19
S Ghailane, Sebastien Pesenti, E Peltier, E Choufani, B Blondel, J L Jouve
PURPOSE: Proximal junctional kyphosis (PJK) is a frequent proximal adjacent segment disease following spinal fusion in adolescent idiopathic scoliosis (AIS) and its rate has been estimated to 28% in the literature. The etiology is multifactorial, and risk factors associated with PJK are controversial. The aim of this study was to demonstrate that the disruption of muscular and bony tissue above the upper instrumented vertebra (UIV) during surgery does not increase the rate of PJK in patients undergoing posterior fusion for adolescent idiopathic scoliosis...
March 25, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28342042/genetic-variant-of-bnc2-gene-is-functionally-associated-with-adolescent-idiopathic-scoliosis-in-chinese-population
#20
Leilei Xu, Chao Xia, Xiaodong Qin, Weixiang Sun, Nelson Leung-Sang Tang, Yong Qiu, Jack Chun-Yiu Cheng, Zezhang Zhu
Adolescent idiopathic scoliosis (AIS) is a structural curvature of the spine that was estimated to affect millions of children worldwide. Recent study shows that the functional variant rs10738445 could add to the risk of AIS through the regulation of BNC2 gene. This study aims to investigate whether the rs10738445 of BNC2 gene is a functional susceptible locus for AIS in the Chinese population and to further clarify the association of the BNC2 expression with the curve severity. SNP rs10738445 was genotyped in 1952 patients and 2492 controls, and further replicated in 693 patients and 254 controls...
March 25, 2017: Molecular Genetics and Genomics: MGG
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