Hitomi Saito, Takashi Ueta, Makoto Araie, Nobuko Enomoto, Mitsuki Kambayashi, Hiroshi Murata, Tsutomu Kikawa, Kazuhisa Sugiyama, Tomomi Higashide, Atsuya Miki, Aiko Iwase, Goji Tomita, Toru Nakazawa, Makoto Aihara, Kyoko Ohno-Matsui, Tae-Woo Kim, Christopher Kai Shun Leung, Linda M Zangwill, Robert N Weinreb
PURPOSE: To investigate factors associated with the severity of prelaminar schisis (PLS) in heathy subjects and glaucoma patients. DESIGN: Prospective cross-sectional study METHODS: Two hundred seventeen eyes of 217 subjects (110 normal eyes and 107 open angle glaucoma eyes). Frequency and severity of PLS were compared between normal and glaucomatous eyes. Multivariate logistic models were used to assess factors associated with the severity of PLS. Factors considered were age, axial length, glaucomatous damage indices, Bruch's membrane opening (BMO) and anterior scleral canal opening parameters, tractional forces (posterior vitreous staging and the presence of Bergmeister's papilla), circumpapillary choroidal thickness, lamina cribrosa (LC) parameters and peripapillary scleral (PPS) angle...
September 7, 2023: American Journal of Ophthalmology