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High frequency stimulation

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https://www.readbyqxmd.com/read/28340445/an-updated-meta-analysis-short-term-therapeutic-effects-of-repeated-transcranial-magnetic-stimulation-in-treating-obsessive-compulsive-disorder
#1
REVIEW
Dong-Dong Zhou, Wo Wang, Gao-Mao Wang, Da-Qi Li, Li Kuang
BACKGROUND: This study was conducted to evaluate the short-term therapeutic effects of using repeated transcranial magnetic stimulation (rTMS) to treat obsessive-compulsive disorder (OCD) and to examine potential influencing factors. METHOD: We searched the PubMed, EMBASE, CENTRAL, Wanfang, CNKI, and Sinomed databases on September 18, 2016 and reviewed the references of previous meta-analyses. Sham-controlled, randomized clinical trials using rTMS to treat OCD were included...
March 18, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28339404/the-influence-of-task-related-training-combined-with-transcutaneous-electrical-nerve-stimulation-on-paretic-upper-limb-muscle-activation-in-patients-with-chronic-stroke
#2
Kyoungsim Jung, Jinhwa Jung, Taesung In, Taehoon Kim, Hwi-Young Cho
OBJECTIVES: This study investigated the efficacy of Task-Related Training (TRT) Combined with Transcutaneous Electrical Nerve Stimulation (TENS) on the improvement of upper limb muscle activation in chronic stroke survivors with mild or moderate paresis. METHODS: A single-blind, randomized clinical trial was conducted with 46stroke survivors with chronic paresis. They were randomly allocated two groups: the TRT+TENS group (n = 23) and the TRT+ placebo TENS (TRT+PLBO) group (n = 23)...
March 23, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28338977/effects-of-augmenting-n-methyl-d-aspartate-receptor-signaling-on-working-memory-and-experience-dependent-plasticity-in-schizophrenia-an-exploratory-study-using-acute-d-cycloserine
#3
Jennifer K Forsyth, Peter Bachman, Daniel H Mathalon, Brian J Roach, Elissa Ye, Robert F Asarnow
Cognitive deficits in schizophrenia have been hypothesized to reflect N-methyl-D-aspartate receptor (NMDAR) dysfunction. However, the mechanisms through which the NMDAR contributes to individual cognitive functions differ. To explore how NMDAR signaling relates to specific cognitive deficits in schizophrenia, we tested the effects of enhancing NMDAR signaling on working memory and experience-dependent plasticity using d-cycloserine (DCS). Plasticity was assessed using an EEG paradigm that utilizes high-frequency visual stimulation (HFvS) to induce neural potentiation, and 2 learning tasks, the information integration (IIT) and weather prediction (WPT) tasks...
March 17, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28337126/competition-between-persistent-na-and-muscarine-sensitive-k-currents-shapes-perithreshold-resonance-and-spike-tuning-in-ca1-pyramidal-neurons
#4
Jorge Vera, Julio Alcayaga, Magdalena Sanhueza
Neurons from many brain regions display intrinsic subthreshold theta-resonance, responding preferentially to theta-frequency oscillatory stimuli. Resonance may contribute to selective communication among neurons and to orchestrate brain rhythms. CA1 pyramidal neurons receive theta activity, generating place fields. In these neurons the expression of perithreshold frequency preference is controversial, particularly in the spiking regime, with evidence favoring either non-resonant (integrator-like) or resonant behavior...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28336195/cognitive-correlates-of-visual-neural-plasticity-in-schizophrenia
#5
Carol Jahshan, Jonathan K Wynn, Daniel H Mathalon, Michael F Green
Neuroplasticity may be an important treatment target to improve the cognitive deficits in schizophrenia (SZ). Yet, it is poorly understood and difficult to assess. Recently, a visual high-frequency stimulation (HFS) paradigm that potentiates electroencephalography (EEG)-based visual evoked potentials (VEP) has been developed to assess neural plasticity in the visual cortex. Using this paradigm, we examined visual plasticity in SZ patients (N=64) and its correlations with clinical symptoms, neurocognition, functional capacity, and community functioning...
March 20, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28334175/attenuated-fast-steady-state-visual-evoked-potentials-during-human-sleep
#6
Omer Sharon, Yuval Nir
During sleep, external sensory events rarely elicit a behavioral response or affect perception. However, how sensory processing differs between wakefulness and sleep remains unclear. A major difficulty in this field stems from using brief auditory stimuli that often trigger nonspecific high-amplitude "K-complex" responses and complicate interpretation. To overcome this challenge, here we delivered periodic visual flicker stimulation across sleep and wakefulness while recording high-density electroencephalography (EEG) in humans...
February 25, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28333372/characterisation-and-functional-mapping-of-surface-potentials-in-the-rat-dorsal-column-nuclei
#7
Alastair J Loutit, Ted Maddess, Stephen J Redmond, John W Morley, Greg J Stuart, Jason R Potas
The brainstem dorsal column nuclei (DCN) play a role in early processing of somatosensory information arising from a variety of functionally distinct peripheral structures, before being transmitted to the cortex via the thalamus. To improve our understanding of how sensory information is represented by the DCN, we characterised and mapped low- (<200 Hz) and high-frequency (550-3300 Hz) components of nerve-evoked DCN surface potentials. DCN surface potentials were evoked by electrical stimulation of the left and right nerves innervating cutaneous (sural nerve), or a mix of cutaneous and deep structures (peroneal nerve), in 8 week-old urethane anaesthetised male Wistar rats...
March 23, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28331355/observing-continuous-change-in-heart-rate-variability-and-photoplethysmography-derived-parameters-during-the-process-of-pain-production-relief-with-thermal-stimuli
#8
Jing-Jhao Ye, Kuan-Ting Lee, Jing-Siang Lin, Chiung-Cheng Chuang
Continuously monitoring and efficiently managing pain has become an important issue. However, no study has investigated a change in physiological parameters during the process of pain production/relief. This study modeled the process of pain production/relief using ramped thermal stimulation (no pain: 37°C water, process of pain production: a heating rate of 1°C/min, and subject feels pain: water kept at the painful temperature for each subject, with each segment lasting 10 min). In this duration, the variation of the heat rate variability and photoplethysmography-derived parameters was observed...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28328013/validation-of-surface-to-volume-ratio-measurements-derived-from-oscillating-gradient-spin-echo-on-a-clinical-scanner-using-anisotropic-fiber-phantoms
#9
Gregory Lemberskiy, Steven H Baete, Martijn A Cloos, Dmitry S Novikov, Els Fieremans
A diffusion measurement in the short-time surface-to-volume ratio (S/V) limit (Mitra et al., Phys Rev Lett. 1992;68:3555) can disentangle the free diffusion coefficient from geometric restrictions to diffusion. Biophysical parameters, such as the S/V of tissue membranes, can be used to estimate microscopic length scales non-invasively. However, due to gradient strength limitations on clinical MRI scanners, pulsed gradient spin echo (PGSE) measurements are impractical for probing the S/V limit. To achieve this limit on clinical systems, an oscillating gradient spin echo (OGSE) sequence was developed...
March 22, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28327942/evaluation-of-the-high-frequency-monopolar-stimulation-technique-for-mapping-and-monitoring-the-corticospinal-tract-in-patients-with-supratentorial-gliomas-a-proposal-for-intraoperative-management-based-on-neurophysiological-data-analysis-in-a-series-of-ninety
#10
Gerard Plans, Isabel Fernández-Conejero, Xavier Rifà-Ros, Alejandro Fernández-Coello, Aleix Rosselló, Andreu Gabarrós
BACKGROUND: Intraoperative identification and preservation of the corticospinal tract is often necessary for glioma resection. OBJECTIVE: To make a proposal for intraoperative management with the high-frequency monopolar stimulation technique for monitoring the corticospinal tract. METHODS: Ninety-two patients operated on with the assistance of the high-frequency monopolar stimulation. Clinical and neurophysiological data have been related with the motor status at 3 months to establish prognostic factors of motor deterioration...
January 13, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28327124/exploring-the-influence-of-cultural-orientations-on-assessment-of-communication-behaviours-during-patient-practitioner-interactions
#11
Kyle J Wilby, Marjan J B Govaerts, Zubin Austin, Diana H J M Dolmans
BACKGROUND: Research has shown that patients' and practitioners' cultural orientations affect communication behaviors and interpretations in cross-cultural patient-practitioner interactions. Little is known about the effect of cultural orientations on assessment of communication behaviors in cross-cultural educational settings. The purpose of this study is to explore cultural orientation as a potential source of assessor idiosyncrasy or between-assessor variability in assessment of communication skills...
March 21, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28326730/-influences-of-vibration-on-rapid-osteogenic-response-of-osteoblasts
#12
Zhu Zhuoli, Zhang Ling, Ma Ruiyang, Gan Xueqi
OBJECTIVE: This study investigated the rapid response of osteoblasts, which were derived from low-magnitude high-frequency vibration (LMHFV). Refractory period-derived memory response was also observed. METHODS: MC3T3-E1 cells were incubated and received LMHFV stimulation (0.49 g, 40 Hz) for 30 min. After application of LMHFV, mRNA levels of earlier osteogenic differentiation markers Runt-related transcription factor 2 (Runx2), collagen typeⅠ(Col-Ⅰ), and alkaline phosphatase (ALP) were immediately detected by real-time fluorescence quantitative polymerase chain reaction in the absence or presence of antioxidant...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28326080/characterization-of-the-highly-prevalent-regulatory-cd24-hi-cd38-hi-b-cell-population-in-human-cord-blood
#13
Ana Esteve-Solé, Irene Teixidó, Angela Deyà-Martínez, Jordi Yagüe, Ana M Plaza-Martín, Manel Juan, Laia Alsina
The newborn's immune system must transition from a sterile haploidentical uterus to the world full of antigens. Regulatory B-cells (Breg; broadly defined as CD19(+)CD24(hi)CD38(hi)) are tolerance promoters in the adult immune system. They can inhibit IFN-γ and IL-17 production by T-cells and are essential in different conditions, including pregnancy. Breg have still not been well characterized in umbilical cord blood, where we hypothesize that they are pivotal in the achievement of tolerance. We studied CD19(+)CD24(hi)CD38(hi) Breg in healthy umbilical cord blood (hUCB) compared to healthy peripheral adult blood (hAPB)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28324983/the-precuneus-may-encode-irrationality-in-human-gambling
#14
P Sacre, M S D Kerr, S Subramanian, K Kahn, J Gonzalez-Martinez, M A Johnson, S V Sarma, J T Gale
Humans often make irrational decisions, especially psychiatric patients who have dysfunctional cognitive and emotional circuitry. Understanding the neural basis of decision-making is therefore essential towards patient management, yet current studies suffer from several limitations. Functional magnetic resonance imaging (fMRI) studies in humans have dominated decision-making neuroscience, but have poor temporal resolution and the blood oxygenation level-dependent signal is only a proxy for neural activity. On the other hand, lesion studies in humans used to infer functionality in decision-making lack characterization of neural activity altogether...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324765/hd-tdcs-in-refractory-lateral-frontal-lobe-epilepsy-patients
#15
Sanaz Ahmadi Karvigh, Mahmoud Motamedi, Mahsa Arzani, Javad Hasan Nia Roshan
PURPOSE: To evaluate the anticonvulsant effect of the novel high definition transcranial direct current stimulation (HD-tDCS) method on patients with refractory lateral frontal lobe epilepsy. The effects of HD-tDCS on working memory were also examined. METHOD: 10 adult patients with intractable lateral frontal lobe epilepsy were studied. A central cathode electrode was placed on the epileptogenic zone according to LTM, and 20-min sessions of 2mA HD-tDCS were applied for 10 consecutive days...
March 14, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28322886/high-gamma-oscillations-in-the-motor-cortex-during-visuo-motor-coordination-a-tacs-interferential-study
#16
E Santarnecchi, A Biasella, E Tatti, A Rossi, D Prattichizzo, S Rossi
BACKGROUND: While the role of beta (∼20Hz), theta (∼5Hz) and alpha (∼10Hz) oscillations in the motor areas have been repeatedly associated with defined properties of motor performance, the investigation of gamma (∼40-90Hz) oscillatory activity is a more recent and still not fully understood component of motor control physiology, despite its potential clinical relevance for motor disorders. OBJECTIVE/HYPOTHESIS: We have implemented an online neuromodulation paradigm based on transcranial alternating current stimulation (tACS) of the dominant motor cortex during a visuo-motor coordination task...
March 18, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28322825/dissection-of-mechanoresponse-elements-in-promoter-sites-of-the-mechanoresponsive-cyr61-gene
#17
Lothar Seefried, Sigrid Mueller-Deubert, Melanie Krug, Almoatazbellah Youssef, Norbert Schuetze, Anita Ignatius, Franz Jakob, Regina Ebert
Mechanotransduction is important for mesenchymal regeneration and differentiation. Exaggerated high or very low impact yields pathological outcome resulting in fracture or tissue atrophy. Pathological strain in animal models was described but tools to dissect the respective stimuli and downstream pathways are limited. We expand the analytical tools to describe DNA strain response elements in a reporter gene approach. Deletion constructs of the human cysteine-rich protein 61 (CYR61) promoter were cloned into luciferase vectors and stably transfected into human telomerase-immortalized mesenchymal stem cells (hMSC-TERT)...
March 16, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28321419/pvaxhsp65-vaccination-primes-for-high-il-10-production-and-decreases-experimental-encephalomyelitis-severity
#18
Sofia Fernanda Gonçalves Zorzella-Pezavento, Fernanda Chiuso-Minicucci, Thais Graziela Donegá França, Larissa Lumi Watanabe Ishikawa, Larissa Camargo da Rosa, Priscila Maria Colavite, Bianca Balbino, Camila Marques, Maura Rosane Valerio Ikoma, Ana Paula Masson, Célio Lopes Silva, Alexandrina Sartori
Experimental autoimmune encephalomyelitis (EAE) is a demyelinating pathology of the central nervous system (CNS) used as a model to study multiple sclerosis immunopathology. EAE has also been extensively employed to evaluate potentially therapeutic schemes. Considering the presence of an immune response directed to heat shock proteins (hsps) in autoimmune diseases and the immunoregulatory potential of these molecules, we evaluated the effect of a previous immunization with a genetic vaccine containing the mycobacterial hsp65 gene on EAE development...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28318948/comparative-assessment-of-intrinsic-mechanical-stimuli-on-knee-cartilage-and-compressed-agarose-constructs
#19
A Completo, C Bandeiras, F Fonseca
A well-established cue for improving the properties of tissue-engineered cartilage is mechanical stimulation. However, the explicit ranges of mechanical stimuli that correspond to favorable metabolic outcomes are elusive. Usually, these outcomes have only been associated with the applied strain and frequency, an oversimplification that can hide the fundamental relationship between the intrinsic mechanical stimuli and the metabolic outcomes. This highlights two important key issues: the firstly is related to the evaluation of the intrinsic mechanical stimuli of native cartilage; the second, assuming that the intrinsic mechanical stimuli will be important, deals with the ability to replicate them on the tissue-engineered constructs...
March 17, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28315614/repetitive-transcranial-magnetic-stimulation-for-treating-the-symptoms-of-schizophrenia-a-prisma-compliant-meta-analysis
#20
Hairong He, Jun Lu, Lihong Yang, Jie Zheng, Fan Gao, Yajing Zhai, Junqin Feng, Yajuan Fan, Xiancang Ma
OBJECTIVE: To explore the efficacies of 1-Hz (low frequency) and 10-Hz (high frequency) repetitive transcranial magnetic stimulation (rTMS) in treating auditory hallucinations and negative symptoms of schizophrenia, respectively. METHODS: Electronic databases were searched to identify relevant literature. Standard mean difference (SMD) and 95% confidence interval (CI) values were used to evaluate the effects of rTMS. The stability and sensitivity of the results, the source of heterogeneity, and the recommended grade of the evidence were also analyzed...
February 22, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
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