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Particulate matter and diabet

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https://www.readbyqxmd.com/read/28429404/air-pollution-weight-loss-and-metabolic-benefits-of-bariatric-surgery-a-potential-model-for-study-of-metabolic-effects-of-environmental-exposures
#1
R Ghosh, W J Gauderman, H Minor, H A Youn, F Lurmann, K R Cromar, L Chatzi, B Belcher, C R Fielding, R McConnell
BACKGROUND: Emerging experimental evidence suggests that air pollution may contribute to development of obesity and diabetes, but studies of children are limited. OBJECTIVES: We hypothesized that pollution effects would be magnified after bariatric surgery for treatment of obesity, reducing benefits of surgery. METHODS: In 75 obese adolescents, excess weight loss (EWL), high-density lipoprotein (HDL) cholesterol, triglycerides, alkaline phosphatase (ALP) and hemoglobin A1c (HbA1c ) were measured prospectively at baseline and following laparoscopic adjustable gastric banding (LAGB)...
April 21, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/28420118/ambient-air-pollution-and-out-of-hospital-cardiac-arrest-in-beijing-china
#2
Ruixue Xia, Guopeng Zhou, Tong Zhu, Xueying Li, Guangfa Wang
Air pollutants are associated with cardiovascular death; however, there is limited evidence of the effects of different pollutants on out-of-hospital cardiac arrests (OHCAs) in Beijing, China. We aimed to investigate the associations of OHCAs with the air pollutants PM2.5-10 (coarse particulate matter), PM2.5 (particles ≤2.5 μm in aerodynamic diameter), nitrogen dioxide (NO₂), sulfur dioxide (SO₂), carbon monoxide (CO), and ozone (O₃) between 2013 and 2015 using a time-stratified case-crossover study design...
April 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28411585/the-association-between-air-pollution-and-type-2-diabetes-in-a-large-cross-sectional-study-in-leicester-the-champions-study
#3
Gary O'Donovan, Yogini Chudasama, Samuel Grocock, Roland Leigh, Alice M Dalton, Laura J Gray, Thomas Yates, Charlotte Edwardson, Sian Hill, Joe Henson, David Webb, Kamlesh Khunti, Melanie J Davies, Andrew P Jones, Danielle H Bodicoat, Alan Wells
BACKGROUND: Observational evidence suggests there is an association between air pollution and type 2 diabetes; however, there is high risk of bias. OBJECTIVE: To investigate the association between air pollution and type 2 diabetes, while reducing bias due to exposure assessment, outcome assessment, and confounder assessment. METHODS: Data were collected from 10,443 participants in three diabetes screening studies in Leicestershire, UK. Exposure assessment included standard, prevailing estimates of outdoor nitrogen dioxide and particulate matter concentrations in a 1×1km area at the participant's home postcode...
April 12, 2017: Environment International
https://www.readbyqxmd.com/read/28368218/fine-particulate-matter-pm2-5-a-risk-factor-for-rat-gestational-diabetes-with-altered-blood-glucose-and-pancreatic-glut2-expression
#4
Liu Yi, Chen Wei, Wang Fan
Recent studies have shown an intriguing association between air pollution and diabetic risk. This study was to investigate the impact of fine particulate matter (PM2.5) on glucose consequences and pancreas glucose transporter2 (GLUT2) expression in a gestational diabetes mellitus (GDM) rat model. GDM rats were exposed to a low PM2.5 dose during pregnancy. After exposure, interleukin-6 (IL-6) and blood routine tests (BRT) were detected. Pancreas underwent pathologic examination. The levels of pancreatic homogenate glutathione peroxidase (GSH-Px), methane dicarboxylic aldehyde (MDA) and GLUT2 were detected...
April 3, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28346907/long-term-associations-of-modeled-and-self-reported-measures-of-exposure-to-air-pollution-and-noise-at-residence-on-prevalent-hypertension-and-blood-pressure
#5
Anitha Pitchika, Regina Hampel, Kathrin Wolf, Ute Kraus, Josef Cyrys, Wolfgang Babisch, Annette Peters, Alexandra Schneider
Air pollution, traffic noise and noise annoyance are suggested to be associated with hypertension and blood pressure (BP); however, the evidence remains inconsistent. Our study examined the long-term associations of modeled and self-reported measures of air pollution and traffic noise on prevalent hypertension and BP. We analyzed cross-sectional data from 2552 participants aged 31-72years from the KORA F4 (2006-2008) study conducted in the region of Augsburg, Germany. Land-use regression models were used to estimate residential long-term exposure to particulate matter <2...
March 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28212639/erectile-dysfunction-and-exposure-to-ambient-air-pollution-in-a-nationally-representative-cohort-of-older-men
#6
Lindsay A Tallon, Justin Manjourides, Vivian C Pun, Murray A Mittleman, Marianthi-Anna Kioumourtzoglou, Brent Coull, Helen Suh
BACKGROUND: Little is known about the association between air pollution and erectile dysfunction (ED), a disorder occurring in 64% of men over the age of 70, and to date, no studies have been published. To address this significant knowledge gap, we explored the relationship between ED and air pollution in a group of older men who were part of the National Social Life, Health, and Aging Project (NSHAP), a nationally representative cohort study of older Americans. METHODS: We obtained incident ED status and participant data for 412 men (age 57-85)...
February 17, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28169030/association-of-pm2-5-with-diabetes-asthma-and-high-blood-pressure-incidence-in-canada-a-spatiotemporal-analysis-of-the-impacts-of-the-energy-generation-and-fuel-sales
#7
Weeberb J Requia, Matthew D Adams, Petros Koutrakis
Numerous studies have reported an association between fine particulate matter (PM2.5) and human health. Often these relationships are influenced by environmental factor that varies spatially and/or temporally. To our knowledge, there are no studies in Canada that have considered energy generation and fuel sales as PM2.5 effects modifiers. Determining exposure and disease-specific risk factors over space and time is crucial for disease prevention and control. In this study, we evaluated the association of PM2...
April 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28153529/ambient-ozone-and-incident-diabetes-a-prospective-analysis-in-a-large-cohort-of-african-american-women
#8
Michael Jerrett, Robert Brook, Laura F White, Richard T Burnett, Jeffrey Yu, Jason Su, Edmund Seto, Julian Marshall, Julie R Palmer, Lynn Rosenberg, Patricia F Coogan
BACKGROUND: Ozone is a ubiquitous air pollutant with increasing concentrations in many populous regions. Toxicological studies show that ozone can cause oxidative stress and increase insulin resistance. These pathways may contribute to metabolic changes and diabetes formation. In this paper, we investigate the association between ozone and incident type 2 diabetes in a large cohort of African American women. METHODS: We used Cox proportional hazards models to calculate hazard ratios (HRs) for incident type 2 diabetes associated with exposure to ozone in a cohort of 45,231 African American women living in 56 metropolitan areas across the United States...
January 30, 2017: Environment International
https://www.readbyqxmd.com/read/28142053/interactions-between-cigarette-smoking-and-ambient-pm2-5-for-cardiovascular-mortality
#9
Michelle C Turner, Aaron Cohen, Richard T Burnett, Michael Jerrett, W Ryan Diver, Susan M Gapstur, Daniel Krewski, Jonathan M Samet, C Arden Pope
Associations between long-term exposure to ambient fine particulate matter (PM2.5) and all-cause and cardiovascular mortality are well documented however less is known regarding possible interactions with cigarette smoking. We previously reported a supra-additive synergistic relationship between PM2.5 and cigarette smoking for lung cancer mortality. Here we examine interactions for all-cause and cardiovascular mortality among 429,406 current or never smoking participants in the prospective American Cancer Society Cancer Prevention Study-II with modeled PM2...
April 2017: Environmental Research
https://www.readbyqxmd.com/read/28137791/longitudinal-associations-between-ambient-air-pollution-with-insulin-sensitivity-%C3%AE-cell-function-and-adiposity-in-los-angeles-latino-children
#10
Tanya L Alderete, Rima Habre, Claudia M Toledo-Corral, Kiros Berhane, Zhanghua Chen, Frederick W Lurmann, Marc J Weigensberg, Michael I Goran, Frank D Gilliland
Evidence suggests that ambient air pollution (AAP) exposure may contribute to the development of obesity and type 2 diabetes. The objective of this study was to determine whether exposure to elevated concentrations of nitrogen dioxide (NO2) and particulate matter with aerodynamic diameter less than 2.5 (PM2.5) had adverse effects on longitudinal measures of insulin sensitivity, β-cell function, and obesity in children at high risk for developing diabetes. Overweight and obese Latino children (8-15 years; n=314) were enrolled between 2001-2012 from Los Angeles, California and followed for an average of 3...
January 30, 2017: Diabetes
https://www.readbyqxmd.com/read/28122165/association-between-particulate-matter-2-5-and-diabetes-mellitus-a-meta-analysis-of-cohort-studies
#11
Dian He, Shaowen Wu, Haiping Zhao, Hongyan Qiu, Yang Fu, Xingming Li, Yan He
AIMS/INTRODUCTION: This Meta-analysis was conducted to assess the association between exposure to the level of atmospheric particulate matter 2.5 (PM2.5, fine particulate matter with aerodynamic diameter less than 2.5 μm) with type 2 diabetes mellitus (T2DM) or gestational diabetes mellitus (GDM). MATERIALS AND METHODS: We searched the Medline, EMBASE, Cochrane and Web of Science databases to obtain articles according to the responding literature search strategies...
January 25, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/27879970/mortality-hospital-days-and-expenditures-attributable-to-ambient-air-pollution-from-particulate-matter-in-israel
#12
Gary M Ginsberg, Ehud Kaliner, Itamar Grotto
BACKGROUND: Worldwide, ambient air pollution accounts for around 3.7 million deaths annually. Measuring the burden of disease is important not just for advocacy but also is a first step towards carrying out a full cost-utility analysis in order to prioritise technological interventions that are available to reduce air pollution (and subsequent morbidity and mortality) from industrial, power generating and vehicular sources. METHODS: We calculated the average national exposure to particulate matter particles less than 2...
2016: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/27835752/chemical-components-of-respirable-particulate-matter-associated-with-emergency-hospital-admissions-for-type-2-diabetes-mellitus-in-hong-kong
#13
Shengzhi Sun, Hong Qiu, Kin-Fai Ho, Linwei Tian
BACKGROUND: Epidemiological studies have shown that short-term exposure to particulate matter (PM) mass is associated with diabetes morbidity and mortality, although inconsistencies still exist. Variation of chemical components in PM may have contributed to these inconsistencies. We hypothesize that certain components of respirable particulate matter (PM10), not simply PM10 mass, can exacerbate symptoms or cause acute complications for type 2 diabetes mellitus (T2DM). METHODS: We used a Poisson time-series model to examine the association between 17 chemical components of PM10 and daily emergency hospital admissions for T2DM among residents aged 65years or above from January 1998 to December 2007 in Hong Kong...
December 2016: Environment International
https://www.readbyqxmd.com/read/27788733/-fine-particulate-matter-and-nonalcoholic-fatty-liver-disease
#14
M Li, Y M Li
Fine particulate matter is defined as the particulate matter with an aerodynamic diameter of < 2.5 μm, i.e., PM2.5. Its surface absorbs large amounts of toxic and hazardous substances, which can deposit in pulmonary alveoli through respiration and reach other organs through pulmonary ventilation. Many studies have confirmed that PM2.5 is closely associated with pulmonary and cardiovascular diseases. Nonalcoholic fatty liver disease(NAFLD)has similar risk factors as these diseases, as well as obesity, hyperlipidemia, and type 2 diabetes, and it is considered a part of metabolic syndrome...
September 20, 2016: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/27780802/association-between-short-term-exposure-to-pm2-5-and-pm10-and-mortality-in-susceptible-subgroups-a-multisite-case-crossover-analysis-of-individual-effect-modifiers
#15
Ester Rita Alessandrini, Massimo Stafoggia, Annunziata Faustini, Giovanna Berti, Cristina Canova, Aldo De Togni, Katiuscia Di Biagio, Bianca Gherardi, Simone Giannini, Paolo Lauriola, Paolo Pandolfi, Giorgia Randi, Andrea Ranzi, Lorenzo Simonato, Stefano Zauli Sajani, Ennio Cadum, Francesco Forastiere
We performed a multisite study to evaluate demographic and clinical conditions as potential modifiers of the particulate matter (PM)-mortality association. We selected 228,619 natural deaths of elderly persons (ages ≥65 years) that occurred in 12 Italian cities during the period 2006-2010. Individual data on causes of death, age, sex, location of death, and preexisting chronic and acute conditions from the previous 5 years' hospitalizations were collected. City-specific conditional logistic regression models were applied within the case-crossover "time-stratified" framework, followed by random-effects meta-analysis...
October 25, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27745901/ambient-air-pollution-and-the-risk-of-central-retinal-artery-occlusion
#16
Hui-Chen Cheng, Ren-Hao Pan, Huan-Jui Yeh, K Robert Lai, May-Yung Yen, Chien-Lung Chan, An-Guor Wang
PURPOSE: To investigate whether daily changes in ambient air pollution were associated with an increased risk of central retinal artery occlusion (CRAO). DESIGN: Retrospective population-based cohort study. PARTICIPANTS: We identified patients newly diagnosed with CRAO between 2001 and 2013 in a representative database of 1 000 000 patients that were randomly selected from all registered beneficiaries of the National Health Insurance program in Taiwan...
October 13, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27743970/association-of-temporal-distribution-of-fine-particulate-matter-with-glucose-homeostasis-during-pregnancy-in-women-of-chiayi-city-taiwan
#17
Mei-Chun Lu, Panchalli Wang, Tsun-Jen Cheng, Chun-Pai Yang, Yuan-Horng Yan
BACKGROUND: To investigate the effects of fine particulate matter (PM2.5) on the indicators of glucose homeostasis during pregnancy. METHODS: A total of 3589 non-diabetic pregnant women who underwent a 3-h 100-g oral glucose tolerance test (OGTT) were enrolled from a tertiary teaching hospital in Chiayi City, Taiwan between 2006 and 2014. Fasting, 1-h, 2-h, and 3-h glucose levels after an OGTT were used as indicators of glucose homeostasis. PM2.5 and other air pollution data were obtained from one fixed-site monitoring station (Chiayi City station) operated by Taiwan Environmental Protection Administration (EPA)...
January 2017: Environmental Research
https://www.readbyqxmd.com/read/27708206/short-term-exposure-to-ambient-fine-particulate-matter-pm2-5-and-pm10-and-the-risk-of-heart-rhythm-abnormalities-and-stroke
#18
Małgorzata Kowalska, Krzysztof Kocot
Results of epidemiological studies suggest a significant impact of ambient particulate matter air pollution (PM10 and PM2,5) on the health of the population. Increased level of these pollutants is connected with increased rate of daily mortality and hospitalizations due to cardiovascular diseases. Among analyzed health effects, heart arrhythmias and stroke are mentioned most frequently. The aim of the study was to present the current knowledge of potential influence of the exposure to fine particulate matter on the presence of arrhythmias and strokes...
September 28, 2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/27650313/the-nlrp3-inflammasome-in-pathogenic-particle-and-fibre-associated-lung-inflammation-and-diseases
#19
REVIEW
Mutlay Sayan, Brooke T Mossman
The concept of the inflammasome, a macromolecular complex sensing cell stress or danger signals and initiating inflammation, was first introduced approximately a decade ago. Priming and activation of these intracellular protein platforms trigger the maturation of pro-inflammatory chemokines and cytokines, most notably, interleukin-1β (IL-1β) and IL-18, to promulgate innate immune defenses. Although classically studied in models of gout, Type II diabetes, Alzheimer's disease, and multiple sclerosis, the importance and mechanisms of action of inflammasome priming and activation have recently been elucidated in cells of the respiratory tract where they modulate the responses to a number of inhaled pathogenic particles and fibres...
September 20, 2016: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/27605624/association-between-long-term-exposure-to-air-pollution-and-biomarkers-related-to-insulin-resistance-subclinical-inflammation-and-adipokines
#20
Kathrin Wolf, Anita Popp, Alexandra Schneider, Susanne Breitner, Regina Hampel, Wolfgang Rathmann, Christian Herder, Michael Roden, Wolfgang Koenig, Christa Meisinger, Annette Peters
Insulin resistance (IR) is present long before the onset of type 2 diabetes and results not only from inherited and lifestyle factors but also likely from environmental conditions. We investigated the association between modeled long-term exposure to air pollution at residence and biomarkers related to IR, subclinical inflammation, and adipokines. Data were based on 2,944 participants of the KORA (Cooperative Health Research in the Region Augsburg) F4 study conducted in southern Germany (2006-2008). We analyzed associations between individual air pollution concentration estimated by land use regression and HOMA-IR, glucose, insulin, HbA1c, leptin, and high-sensitivity C-reactive protein levels from fasting samples using multivariable linear regression models...
November 2016: Diabetes
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