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Noise and diabet

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https://www.readbyqxmd.com/read/28892786/gestational-diabetes-mellitus-and-exposure-to-ambient-air-pollution-and-road-traffic-noise-a-cohort-study
#1
Marie Pedersen, Sjurdur F Olsen, Thorhallur I Halldorsson, Cuilin Zhang, Dorrit Hjortebjerg, Matthias Ketzel, Charlotta Grandström, Mette Sørensen, Peter Damm, Jens Langhoff-Roos, Ole Raaschou-Nielsen
BACKGROUND: Road traffic is a main source of air pollution and noise. Both exposures have been associated with type 2 diabetes, but associations with gestational diabetes mellitus (GDM) have been studied less. OBJECTIVES: We aimed to examine single and joint associations of exposure to air pollution and road traffic noise on GDM in a prospective cohort. METHODS: We identified GDM cases from self-reports and hospital records, using two different criteria, among 72,745 singleton pregnancies (1997-2002) from the Danish National Birth Cohort...
September 8, 2017: Environment International
https://www.readbyqxmd.com/read/28889780/prevalence-of-hearing-loss-and-associated-factors-in-subjects-with-normal-otoscopy-a-national-cross-sectional-study
#2
Hong Ju Park, Myung Hoon Yoo, Sook-Young Woo, Seon Woo Kim, Yang-Sun Cho
OBJECTIVE: To report the prevalence of hearing loss (HL) and associated factors in a nationwide study. DESIGN: Cross-sectional study. STUDY SAMPLE: We investigated the prevalence of HL in 10,845 participants ≥12 years of age and analysed the associated factors with HL from 7434 participants ≥40 years of age. RESULTS: The prevalence of worse ear HL was 21.9% (1.2% in youngest and 81.9% in oldest) and that of better ear was 12...
September 11, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28888021/simultaneous-monitoring-of-single-cell-and-of-micro-organ-activity-by-pedot-pss-covered-multi-electrode-arrays
#3
Dimitrios A Koutsouras, Romain Perrier, Ariana Villarroel Marquez, Antoine Pirog, Eileen Pedraza, Eric Cloutet, Sylvie Renaud, Matthieu Raoux, George G Malliaras, Jochen Lang
Continuous and long-term monitoring of cellular and micro-organ activity is required for new insights into physiology and novel technologies such as Organs-on-Chip. Moreover, recent advances in stem cell technology and especially in the field of diabetes call for non-invasive approaches in quality testing of the large quantities of surrogate pancreatic islets to be generated. Electrical activity of such a micro-organ results in single cell action potentials (APs) of high frequency and in low frequency changes in local field potentials (slow potentials or SPs), reflecting coupled cell activity and overall organ physiology...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28841762/comparison-of-different-compressed-sensing-algorithms-for-low-snr-19-f-mri-applications-imaging-of-transplanted-pancreatic-islets-and-cells-labeled-with-perfluorocarbons
#4
Sayuan Liang, Tom Dresselaers, Karim Louchami, Ce Zhu, Yipeng Liu, Uwe Himmelreich
Transplantation of pancreatic islets is a possible treatment option for patients suffering from Type I diabetes. In vivo imaging of transplanted islets is important for assessment of the transplantation site and islet distribution. Thanks to its high specificity, the absence of intrinsic background signal in tissue and its potential for quantification, (19) F MRI is a promising technique for monitoring the fate of transplanted islets in vivo. In order to overcome the inherent low sensitivity of (19) F MRI, leading to long acquisition times with low signal-to-noise ratio (SNR), compressed sensing (CS) techniques are a valuable option...
August 25, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28835436/in-vitro-contraction-protects-against-palmitate-induced-insulin-resistance-in-c2c12-myotubes
#5
Stephan Nieuwoudt, Anny Mulya, Ciaran E Fealy, Elizabeth Martelli, Srinivasan Dasarathy, Sathyamangla V Naga Prasad, John P Kirwan
We are interested in understanding mechanisms that govern the protective role of exercise against lipid-induced insulin resistance, a key driver of type 2 diabetes. In this context, cell culture models provide a level of abstraction that aid in our understanding of cellular physiology. Here we describe the development of an in vitro myotube contraction system that provides this protective effect, and which we have harnessed to investigate lipid-induced insulin resistance. C2C12 myocytes were differentiated into contractile myotubes...
August 23, 2017: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/28806613/automatic-blood-vessels-segmentation-based-on-different-retinal-maps-from-octa-scans
#6
Nabila Eladawi, Mohammed Elmogy, Omar Helmy, Ahmed Aboelfetouh, Alaa Riad, Harpal Sandhu, Shlomit Schaal, Ayman El-Baz
The retinal vascular network reflects the health of the retina, which is a useful diagnostic indicator of systemic vascular. Therefore, the segmentation of retinal blood vessels is a powerful method for diagnosing vascular diseases. This paper presents an automatic segmentation system for retinal blood vessels from Optical Coherence Tomography Angiography (OCTA) images. The system segments blood vessels from the superficial and deep retinal maps for normal and diabetic cases. Initially, we reduced the noise and improved the contrast of the OCTA images by using the Generalized Gauss-Markov random field (GGMRF) model...
August 7, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28783619/fully-automated-segmentation-of-fluid-cyst-regions-in-optical-coherence-tomography-images-with-diabetic-macular-edema-using-neutrosophic-sets-and-graph-algorithms
#7
Abdolreza Rashno, Dara D Koozekanani, Paul M Drayna, Behzad Nazari, Saeed Sadri, Hossein Rabbani, Keshab K Parhi
This paper presents a fully-automated algorithm to segment fluid-associated (fluid-filled) and cyst regions in optical coherence tomography (OCT) retina images of the subjects with diabetic macular edema (DME). The OCT image is segmented using a novel neutrosophic transformation and a graph-based shortest path method. In neutrosophic domain, an image g is transformed into three sets: T (true), I (indeterminate) that represents noise, and F (false). This paper makes four key contributions. First, a new method is introduced to compute the indeterminacy set I, and a new λ-correction operation is introduced to compute the set T in neutrosophic domain...
July 31, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28721941/blood-glucose-concentration-control-for-type-1-diabetic-patients-a-non-linear-suboptimal-approach
#8
Yazdan Batmani
In this study, a closed-loop treatment strategy is proposed for the control of blood glucose levels in type 1 diabetic patients. Toward this end, a non-linear technique for designing suboptimal tracking controllers, called the state-dependent Riccati equation tracker, is used based on a mathematical model of the glucose-insulin regulatory system. Since two state variables of the utilised model are not available to the controller, a non-linear filter is also designed to estimate these variables using the measured blood glucose concentration...
August 2017: IET Systems Biology
https://www.readbyqxmd.com/read/28720778/visualization-of-kidney-fibrosis-in-diabetic-nephropathy-by-long-diffusion-tensor-imaging-mri-with-spin-echo-sequence
#9
Jun-Ya Kaimori, Yoshitaka Isaka, Masaki Hatanaka, Satoko Yamamoto, Naotsugu Ichimaru, Akihiko Fujikawa, Hiroshi Shibata, Akira Fujimori, Sosuke Miyoshi, Takashi Yokawa, Kagayaki Kuroda, Toshiki Moriyama, Hiromi Rakugi, Shiro Takahara
Renal fibrosis (RF) is an indicator for progression of chronic kidney disease (CKD). Although diabetic nephropathy (DN) is the leading cause of CKD and end-stage renal disease in Western populations, the ability of MRI to evaluate RF in DN patients has not been determined. As a first step to identify possible MRI methods for RF evaluation, we examined the use of diffusion tensor imaging (DTI) MRI to evaluate RF in a rat model of DN (SHR/NDmcr-cp(cp/cp): SHR/ND). The signal-to-noise ratio in DTI MRI was enhanced using a spin-echo sequence, and a special kidney attachment was developed for long-term stabilization...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28720223/absorbance-detector-for-high-performance-liquid-chromatography-based-on-a-deep-uv-light-emitting-diode-at-235nm
#10
João Flavio da Silveira Petruci, Michael G Liebetanz, Arnaldo Alves Cardoso, Peter C Hauser
In this communication, we describe a flow-through optical absorption detector for HPLC using for the first time a deep-UV light-emitting diode with an emission band at 235nm as light source. The detector is also comprised of a UV-sensitive photodiode positioned to enable measurement of radiation through a flow-through cuvette with round aperture of 1mm diameter and optical path length of 10mm, and a second one positioned as reference photodiode; a beam splitter and a power supply. The absorbance was measured and related to the analyte concentration by emulating the Lambert-Beer law with a log-ratio amplifier circuitry...
July 11, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28720102/environmental-lifestyle-factors-in-the-pathogenesis-and-prevention-of-type-2-diabetes
#11
REVIEW
Hubert Kolb, Stephan Martin
BACKGROUND: Environmental and lifestyle changes, in addition to the ageing of populations, are generally believed to account for the rapid global increase in type 2 diabetes prevalence and incidence in recent decades. DISCUSSION: In this review, we present a comprehensive overview of factors contributing to diabetes risk, including aspects of diet quality and quantity, little physical activity, increased monitor viewing time or sitting in general, exposure to noise or fine dust, short or disturbed sleep, smoking, stress and depression, and a low socioeconomic status...
July 19, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28707484/autoregressive-modeling-of-drift-and-random-error-to-characterize-a-continuous-intravascular-glucose-monitoring-sensor
#12
Tony Zhou, Jennifer L Dickson, J Geoffrey Chase
BACKGROUND: Continuous glucose monitoring (CGM) devices have been effective in managing diabetes and offer potential benefits for use in the intensive care unit (ICU). Use of CGM devices in the ICU has been limited, primarily due to the higher point accuracy errors over currently used traditional intermittent blood glucose (BG) measures. General models of CGM errors, including drift and random errors, are lacking, but would enable better design of protocols to utilize these devices. This article presents an autoregressive (AR) based modeling method that separately characterizes the drift and random noise of the GlySure CGM sensor (GlySure Limited, Oxfordshire, UK)...
July 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28697826/-risk-factors-for-congenital-heart-disease-in-chinese-neonates-a-meta-analysis
#13
Yi Liu, Bei Zhu, Lin Zhuo, Ming-Yu He, Yang Xu, Tong-Tong Wang, Qing-Qing Cai, Bin Hu, Ji-Cheng Xu, Wen-Hui Zhang
OBJECTIVE: To investigate the major risk factors for congenital heart disease (CHD) in Chinese neonates and to provide a reference for the prevention of CHD. METHODS: A literature search was performed to collect the case-control studies on the risk factors for CHD in Chinese neonates published in 2001-2016. The relevant data were extracted accordingly. The quality of included studies was assessed by Newcastle-Ottawa Scale. Sensitivity analysis was conducted using different models to analyze the same data...
July 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28685099/integrative-analysis-of-pathway-deregulation-in-obesity
#14
Francesc Font-Clos, Stefano Zapperi, Caterina A M La Porta
Obesity is a pandemic disease, linked to the onset of type 2 diabetes and cancer. Transcriptomic data provides a picture of the alterations in regulatory and metabolic activities associated with obesity, but its interpretation is typically blurred by noise. Here, we solve this problem by collecting publicly available transcriptomic data from adipocytes and removing batch effects using singular value decomposition. In this way we obtain a gene expression signature of 38 genes associated to obesity and identify the main pathways involved...
2017: NPJ Systems Biology and Applications
https://www.readbyqxmd.com/read/28678080/noise-history-and-auditory-function-in-young-adults-with-and-without-type-1-diabetes-mellitus
#15
Christopher Spankovich, Colleen G Le Prell, Edward Lobarinas, Linda J Hood
OBJECTIVES: The purpose of this study was to examine the relationship between noise exposure history, type 1 diabetes mellitus (DM), and suprathreshold measures of auditory function. DESIGN: A cross-sectional study was conducted; 20 normal-hearing participants without type 1 DM were matched on age and sex to 20 normal-hearing participants with type 1 DM (n=40). Participants, all having normal audiometric thresholds, completed noise history questionnaires and a battery of auditory physiological tests including transient evoked otoacoustic emissions, distortion product otoacoustic emissions, and auditory brainstem responses (ABR) at 80 dB nHL and at 2 different stimulus rates in both ears...
July 1, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28660337/differential-mobility-spectrometry-tandem-mass-spectrometry-with-multiple-ion-monitoring-for-the-bioanalysis-of-liraglutide
#16
Xiangjun Meng, Haitong Xu, Zhi Zhang, John Paul Fawcett, Junru Li, Yan Yang, Jingkai Gu
Liraglutide is a glucagon-like peptide-1 analog for the treatment of type 2 diabetes. Major interference in plasma of human and animals and low fragment signal in tandem mass spectrometry are the main difficulties encountered in the bioanalysis of liraglutide. In this study, by combining differential mobility spectrometry (DMS) with multiple ion monitoring detection (MIM), a liquid chromatography differential mobility spectrometry tandem mass spectrometry with multiple ion monitoring detection (LC-DMS-MIM) method was developed for the quantitation of liraglutide in dog plasma...
June 28, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28659725/system-level-meta-analysis-of-microarray-datasets-for-elucidation-of-diabetes-mellitus-pathobiology
#17
Aditya Saxena, Kumar Sachin, Ashok Kumar Bhatia
BACKGROUND: Type 2 diabetes (T2D) is a common multi-factorial disease that is primarily ac-counted to ineffective insulin action in lowering blood glucose level and later escalates to impaired insu-lin secretion by pancreatic β cells. Deregulation in insulin signaling to its target organs is attributed to this disease phenotype. Various genome-wide microarray studies from multiple insulin responsive tis-sues have been conducted in past but due to inherent noise in microarray data and heterogeneity in dis-ease etiology; reproduction of prioritized pathways/genes is very low across various studies...
June 2017: Current Genomics
https://www.readbyqxmd.com/read/28604634/modeling-the-error-of-the-medtronic-paradigm-veo-enlite-glucose-sensor
#18
Lyvia Biagi, Charrise M Ramkissoon, Andrea Facchinetti, Yenny Leal, Josep Vehi
Continuous glucose monitors (CGMs) are prone to inaccuracy due to time lags, sensor drift, calibration errors, and measurement noise. The aim of this study is to derive the model of the error of the second generation Medtronic Paradigm Veo Enlite (ENL) sensor and compare it with the Dexcom SEVEN PLUS (7P), G4 PLATINUM (G4P), and advanced G4 for Artificial Pancreas studies (G4AP) systems. An enhanced methodology to a previously employed technique was utilized to dissect the sensor error into several components...
June 12, 2017: Sensors
https://www.readbyqxmd.com/read/28584317/exposure-to-self-reported-occupational-noise-and-diabetes-a-cross-sectional-relationship-in-7th-european-social-survey-ess7-2014
#19
Angel Mario Dzhambov
OBJECTIVES: Almost nothing is known about the effect of occupational noise on diabetes, and this is particularly relevant given the wide spread of both noise exposure and diabetes. This study has aimed to determine whether occupational noise exposure is associated with higher risk of diabetes in Europe. MATERIAL AND METHODS: This study is based on 7th European Social Survey (ESS7, 2014) - a multi-country population-based questionnaire survey, which covered 28 221 Europeans aged ≥ 15 years old...
April 14, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28560245/assistive-lesion-emphasis-system-an-assistive-system-for-fundus-image-readers
#20
Samrudhdhi B Rangrej, Jayanthi Sivaswamy
Computer-assisted diagnostic (CAD) tools are of interest as they enable efficient decision-making in clinics and the screening of diseases. The traditional approach to CAD algorithm design focuses on the automated detection of abnormalities independent of the end-user, who can be an image reader or an expert. We propose a reader-centric system design wherein a reader's attention is drawn to abnormal regions in a least-obtrusive yet effective manner, using saliency-based emphasis of abnormalities and without altering the appearance of the background tissues...
April 2017: Journal of Medical Imaging
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