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Noise and diabet

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https://www.readbyqxmd.com/read/28226752/classification-of-sd-oct-volumes-with-multi-pyramids-lbp-and-hog-descriptors-application-to-dme-detections
#1
Khaled Alsaih, Guillaume Lemaitre, Join Massich Vall, Mojdeh Rastgoo, Desire Sidibe, Tien Y Wong, Ecosse Lamoureux, Dan Milea, Carol Y Cheung, Fabrice Meriaudeau, Khaled Alsaih, Guillaume Lemaitre, Join Massich Vall, Mojdeh Rastgoo, Desire Sidibe, Tien Y Wong, Ecosse Lamoureux, Dan Milea, Carol Y Cheung, Fabrice Meriaudeau, Guillaume Lemaitre, Dan Milea, Carol Y Cheung, Desire Sidibe, Ecosse Lamoureux, Join Massich Vall, Mojdeh Rastgoo, Fabrice Meriaudeau, Tien Y Wong, Khaled Alsaih
This paper deals with the automated detection of Diabetic Macular Edema (DME) on Optical Coherence Tomography (OCT) volumes. Our method considers a generic classification pipeline with preprocessing for noise removal and flattening of each B-Scan. Features such as Histogram of Oriented Gradients (HOG) and Local Binary Patterns (LBP) are extracted and combined to create a set of different feature vectors which are fed to a linear-Support Vector Machines (SVM) Classifier. Experimental results show a promising sensitivity/specificity of 0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226026/diabetes-mellitus-and-sensorineural-hearing-loss-is-there-an-association-baseline-of-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil
#2
Alessandra G Samelli, Itamar S Santos, Renata R Moreira, Camila M Rabelo, Laurie P Rolim, Isabela J Bensenõr, Paulo A Lotufo
OBJECTIVES: Although several studies have investigated the effects of diabetes on hearing loss, the relationship between these two conditions remains unclear. Some studies have suggested that diabetes may cause sensorineural hearing loss, whereas others have failed to find an association. The biggest challenge in investigating the association between diabetes and hearing loss is the presence of confounding variables and the complexity of the auditory system. Our study investigated the association between diabetes and sensorineural hearing loss...
January 1, 2017: Clinics
https://www.readbyqxmd.com/read/28193044/engineered-iro2-nio-core-shell-nanowires-for-sensitive-non-enzymatic-detection-of-trace-glucose-in-saliva
#3
Junjun Wang, Lin Xu, Yang Lu, Kuang Sheng, Wei Liu, Cong Chen, Yang Li, Biao Dong, Hongwei Song
Hierarchical core-shell IrO2@NiO nanowires (NWs) have been designed through two simple steps, which combined electrospinning of IrO2 conductive core and chemical bath deposition growth of ultracontinuous NiO nanoflakes. Scanning electron microscopy, transmission electron microscopy, X-ray diffraction, energy-dispersive X-ray spectrometry mapping, and X-ray photoelectron spectroscopy were employed to characterize the morphologies and structures of the as-prepared samples, and the results were also carefully compared with that of pure NiO nanoflowers and IrO2 NWs...
December 20, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/28188327/tactile-stimuli-affect-long-range-correlations-of-stride-interval-and-stride-length-differently-during-walking
#4
Jung Hung Chien, V N Pradeep Ambati, Chun-Kai Huang, Mukul Mukherjee
Sensory feedback below the sole of the foot using sub-threshold mechanical noise significantly reduced postural sway in patients with diabetes and stroke. However, the effects of tactile parameters on walking are still elusive. Specifically, the effects of such parameters on human gait variability need to be studied because of possible rehabilitation outcomes in terms of bringing improvement in temporal and spatial gait parameters. The purpose of this study was to investigate whether different frequency and amplitude combinations of vibro-tactile stimulation of feet would affect stride-to-stride variability in healthy young adults...
February 10, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28107976/sensitive-fluorescent-detection-of-h2o2-and-glucose-in-human-serum-based-on-inner-filter-effect-of-squaric-acid-iron-iii-on-the-fluorescence-of-upconversion-nanoparticle
#5
Hongyu Chen, Aijin Fang, Li He, Youyu Zhang, Shouzhuo Yao
Diabetes mellitus is an epidemic disease that it has became a worldwide public health problem. Thus, blood glucose monitoring has attracted extensive attention. Here, we report a nanosensor based on inner filter effect (IFE) between upconversion nanoparticles (UCNPs) and squaric acid (SQA)-iron(III) for the highly sensitive and selective detection of glucose levels in human serum. In this assay, GOx-catalyzed oxidization of glucose produces gluconic acid and hydrogen peroxide (H2O2). The latter can catalytically oxidize iron(II) to iron(III) which can rapidly (<1min) coordinate with the SQA to produce (SQA)-iron(III)...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28063388/nanostructured-biosensor-for-detecting-glucose-in-tear-by-applying-fluorescence-resonance-energy-transfer-quenching-mechanism
#6
Longyi Chen, Wai Hei Tse, Yi Chen, Matthew W McDonald, James Melling, Jin Zhang
In this paper, a nanostructured biosensor is developed to detect glucose in tear by using fluorescence resonance energy transfer (FRET) quenching mechanism. The designed FRET pair, including the donor, CdSe/ZnS quantum dots (QDs), and the acceptor, dextran-binding malachite green (MG-dextran), was conjugated to concanavalin A (Con A), an enzyme with specific affinity to glucose. In the presence of glucose, the quenched emission of QDs through the FRET mechanism is restored by displacing the dextran from Con A...
May 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27981066/blood-vessel-extraction-of-diabetic-retinopathy-using-optimized-enhanced-images-and-matched-filter
#7
Asit Subudhi, Subhra Pattnaik, Sukanta Sabut
Accurate extraction of structural changes in the blood vessels of the retina is an essential task in diagnosis of retinopathy. Matched filter (MF) technique is the effective way to extract blood vessels, but the effectiveness is reduced due to noisy images. The concept of MF and MF with first-order derivative of Gaussian (MF-FDOG) has been implemented for retina images of the DRIVE database. The optimized particle swarm optimization (PSO) algorithm is used for enhancing the images by edgels to improve the performance of filters...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27876036/diabetes-screening-intervals-based-on-risk-stratification
#8
Sachiko Ohde, Emily McFadden, Gautam A Deshpande, Hiroshi Yokomichi, Osamu Takahashi, Tsuguya Fukui, Rafael Perera, Zentaro Yamagata
BACKGROUND: Guidelines for frequency of Type 2 diabetes mellitus (DM) screening remain unclear, with proposed screening intervals typically based on expert opinion. This study aims to demonstrate that HbA1c screening intervals may differ substantially when considering individual risk for diabetes. METHODS: This was a multi-institutional retrospective open cohort study. Data were collected between April 1999 to March 2014 from one urban and one rural cohort in Japan...
November 22, 2016: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/27811997/effects-of-chronic-noise-on-glucose-metabolism-and-gut-microbiota-host-inflammatory-homeostasis-in-rats
#9
Bo Cui, Zhihui Gai, Xiaojun She, Rui Wang, Zhuge Xi
Chronic noise exposure has been implicated in increased risk of diabetes. However, there is limited experimental evidence of the mechanisms linking chronic noise stress and glucose metabolism. We addressed this in the present study by examining glucose metabolism, immune response, and changes in gut microbiota/host inflammatory homeostasis in rats exposed to noise for 30 consecutive days. Chronic noise exposure increased blood glucose and corticosterone levels for at least 14 days after cessation of noise. Stressed rats also exhibited elevated levels of glycogen and triglyceride in the liver and impaired hepatic insulin production via insulin-induced insulin receptor/insulin receptor substrate 1/glycogen synthase kinase 3β signalling, which persisted for 3-14 days after cessation of noise exposure...
November 4, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27763533/non-enzymatic-glucose-sensing-using-carbon-quantum-dots-decorated-with-copper-oxide-nanoparticles
#10
Houcem Maaoui, Florina Teodoresu, Qian Wang, Guo-Hui Pan, Ahmed Addad, Radhouane Chtourou, Sabine Szunerits, Rabah Boukherroub
Perturbations in glucose homeostasis is critical for human health, as hyperglycemia (defining diabetes) leads to premature death caused by macrovascular and microvascular complications. However, the simple and accurate detection of glucose in the blood at low cost remains a challenging task, although it is of great importance for the diagnosis and therapy of diabetic patients. In this work, carbon quantum dots decorated with copper oxide nanostructures (CQDs/Cu₂O) are prepared by a simple hydrothermal approach, and their potential for electrochemical non-enzymatic glucose sensing is evaluated...
October 18, 2016: Sensors
https://www.readbyqxmd.com/read/27761267/the-association-between-long-working-hours-and-hearing-impairment-in-noise-unexposed-workers-data-from-the-5th-korea-national-health-and-nutrition-examination-survey-knhanes-2010-2012
#11
Jung-Woo Park, Jin-Soo Park, Seyoung Kim, Minkyu Park, Hyunrim Choi, Sinye Lim
BACKGROUND: This study is aimed at finding out the relationship between long working hours, one of major job stress elements, and hearing impairment in unexposed workers to occupational and environmental noise. METHODS: This study was performed on 1628 regular, full-time wage workers between the age of 25-64 who indicated in the survey of having no experience of exposure to noise, normal otoscopic findings, and not suffering from diabetes based on the data from the fifth Korea National Health and Nutrition Examination Survey (KNHANES 2010-2012)...
2016: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27756410/stiff-person-syndrome-in-south-asia
#12
Thashi Chang, Bethan Lang, Angela Vincent
BACKGROUND: Stiff person syndrome is a highly disabling, progressive autoimmune disorder of the central nervous system characterized by muscle rigidity and spasms. Stiff person syndrome is rare, but is believed to be under diagnosed with only 14 cases been reported among a 1.7 billion population in South Asia. We report the first authenticated case from Sri Lanka. CASE PRESENTATION: A 55-year-old Sri Lankan female presented with difficulty in walking and recurrent falls due to progressive muscular rigidity in her lower limbs and trunk with superimposed muscle spasms that occurred in response to unexpected noise, startle or emotional upset...
October 18, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27729094/identification-of-donor-origin-and-condition-of-transplanted-islets-in-situ-in-the-liver-of-a-type-1-diabetic-recipient
#13
Cornelis R van der Torren, Jessica S Suwandi, DaHae Lee, Ernst-Jan T van 't Wout, Gaby Duinkerken, Godelieve Swings, Arend Mulder, Frans H J Claas, Zhidong Ling, Pieter Gillard, Bart Keymeulen, Peter In 't Veld, Bart O Roep
Transplantation of islet allografts into type 1 diabetic recipients usually requires multiple pancreas donors to achieve insulin independence. This adds to the challenges of immunological monitoring of islet transplantation currently relying on surrogate immune markers in peripheral blood. We investigated donor origin and infiltration of islets transplanted in the liver of a T1D patient who died of hemorrhagic stroke four months after successful transplantation with two intraportal islet grafts combining six donors...
October 10, 2016: Cell Transplantation
https://www.readbyqxmd.com/read/27714563/performance-analysis-of-fuzzy-pid-controller-for-blood-glucose-regulation-in-type-1-diabetic-patients
#14
Jyoti Yadav, Asha Rani, Vijander Singh
This paper presents Fuzzy-PID (FPID) control scheme for a blood glucose control of type 1 diabetic subjects. A new metaheuristic Cuckoo Search Algorithm (CSA) is utilized to optimize the gains of FPID controller. CSA provides fast convergence and is capable of handling global optimization of continuous nonlinear systems. The proposed controller is an amalgamation of fuzzy logic and optimization which may provide an efficient solution for complex problems like blood glucose control. The task is to maintain normal glucose levels in the shortest possible time with minimum insulin dose...
December 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/27709075/automated-registration-and-enhanced-processing-of-clinical-optical-coherence-tomography-angiography
#15
Acner Camino, Miao Zhang, Changlei Dongye, Alex D Pechauer, Thomas S Hwang, Steven T Bailey, Brandon Lujan, David J Wilson, David Huang, Yali Jia
BACKGROUND: Motion artifacts degrade the quality of optical coherence tomography angiography (OCTA). Orthogonal registration can eliminate the majority of these artifacts, but some artifacts persist in most clinical images. We evaluate an automated registration algorithm with selective merging and filtering to remove remaining artifacts and improve the quality of images. METHODS: A 70 kHz commercial spectral domain OCT was used to obtain 3 mm × 3 mm OCTA in 10 healthy, 5 age-related macular degeneration (AMD), and 31 diabetic retinopathy (DR) participants...
August 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/27681078/decreases-in-gap-junction-coupling-recovers-ca2-and-insulin-secretion-in-neonatal-diabetes-mellitus-dependent-on-beta-cell-heterogeneity-and-noise
#16
Aleena M Notary, Matthew J Westacott, Thomas H Hraha, Marina Pozzoli, Richard K P Benninger
Diabetes is caused by dysfunction to β-cells in the islets of Langerhans, disrupting insulin secretion and glucose homeostasis. Gap junction-mediated electrical coupling between β-cells in the islet plays a major role in coordinating a pulsatile secretory response at elevated glucose and suppressing insulin secretion at basal glucose. Previously, we demonstrated that a critical number of inexcitable cells can rapidly suppress the overall islet response, as a result of gap junction coupling. This was demonstrated in a murine model of Neonatal Diabetes Mellitus (NDM) involving expression of ATP-insensitive KATP channels, and by a multi-cellular computational model of islet electrical activity...
September 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27635151/improved-ceemdan-and-pso-svr-modeling-for-near-infrared-noninvasive-glucose-detection
#17
Xiaoli Li, Chengwei Li
Diabetes is a serious threat to human health. Thus, research on noninvasive blood glucose detection has become crucial locally and abroad. Near-infrared transmission spectroscopy has important applications in noninvasive glucose detection. Extracting useful information and selecting appropriate modeling methods can improve the robustness and accuracy of models for predicting blood glucose concentrations. Therefore, an improved signal reconstruction and calibration modeling method is proposed in this study. On the basis of improved complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) and correlative coefficient, the sensitive intrinsic mode functions are selected to reconstruct spectroscopy signals for developing the calibration model using the support vector regression (SVR) method...
2016: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/27613658/an-adaptive-nonlinear-basal-bolus-calculator-for-patients-with-type-1-diabetes
#18
Dimitri Boiroux, Tinna Björk Aradóttir, Kirsten Nørgaard, Niels Kjølstad Poulsen, Henrik Madsen, John Bagterp Jørgensen
BACKGROUND: Bolus calculators help patients with type 1 diabetes to mitigate the effect of meals on their blood glucose by administering a large amount of insulin at mealtime. Intraindividual changes in patients physiology and nonlinearity in insulin-glucose dynamics pose a challenge to the accuracy of such calculators. METHOD: We propose a method based on a continuous-discrete unscented Kalman filter to continuously track the postprandial glucose dynamics and the insulin sensitivity...
September 8, 2016: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/27586488/a-fully-automatic-nerve-segmentation-and-morphometric-parameter-quantification-system-for-early-diagnosis-of-diabetic-neuropathy-in-corneal-images
#19
Shumoos Al-Fahdawi, Rami Qahwaji, Alaa S Al-Waisy, Stanley Ipson, Rayaz A Malik, Arun Brahma, Xin Chen
Diabetic Peripheral Neuropathy (DPN) is one of the most common types of diabetes that can affect the cornea. An accurate analysis of the nerve structures can assist the early diagnosis of this disease. This paper proposes a robust, fast and fully automatic nerve segmentation and morphometric parameter quantification system for corneal confocal microscope images. The segmentation part consists of three main steps. First, a preprocessing step is applied to enhance the visibility of the nerves and remove noise using anisotropic diffusion filtering, specifically a Coherence filter followed by Gaussian filtering...
October 2016: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/27572140/in-vivo-retinal-and-choroidal-hypoxia-imaging-using-a-novel-activatable-hypoxia-selective-near-infrared-fluorescent-probe
#20
Shinichi Fukuda, Kensuke Okuda, Genichiro Kishino, Sujin Hoshi, Itsuki Kawano, Masahiro Fukuda, Toshiharu Yamashita, Simone Beheregaray, Masumi Nagano, Osamu Ohneda, Hideko Nagasawa, Tetsuro Oshika
PURPOSE: Retinal hypoxia plays a crucial role in ocular neovascular diseases, such as diabetic retinopathy, retinopathy of prematurity, and retinal vascular occlusion. Fluorescein angiography is useful for identifying the hypoxia extent by detecting non-perfusion areas or neovascularization, but its ability to detect early stages of hypoxia is limited. Recently, in vivo fluorescent probes for detecting hypoxia have been developed; however, these have not been extensively applied in ophthalmology...
December 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
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