keyword
https://read.qxmd.com/read/38640241/coin-sized-fully-integrated-and-minimally-invasive-continuous-glucose-monitoring-system-based-on-organic-electrochemical-transistors
#1
JOURNAL ARTICLE
Jing Bai, Dingyao Liu, Xinyu Tian, Yan Wang, Binbin Cui, Yilin Yang, Shilei Dai, Wensheng Lin, Jixiang Zhu, Jinqiang Wang, Aimin Xu, Zhen Gu, Shiming Zhang
Continuous glucose monitoring systems (CGMs) are critical toward closed-loop diabetes management. The field's progress urges next-generation CGMs with enhanced antinoise ability, reliability, and wearability. Here, we propose a coin-sized, fully integrated, and wearable CGM, achieved by holistically synergizing state-of-the-art interdisciplinary technologies of biosensors, minimally invasive tools, and hydrogels. The proposed CGM consists of three major parts: (i) an emerging biochemical signal amplifier, the organic electrochemical transistor (OECT), improving the signal-to-noise ratio (SNR) beyond traditional electrochemical sensors; (ii) a microneedle array to facilitate subcutaneous glucose sampling with minimized pain; and (iii) a soft hydrogel to stabilize the skin-device interface...
April 19, 2024: Science Advances
https://read.qxmd.com/read/38640128/the-impact-of-environmental-and-occupational-noise-on-maternal-and-perinatal-pregnancy-outcomes
#2
JOURNAL ARTICLE
Mara Ulin, Nneoma Edokobi, Brandon Ganjineh, Everett F Magann, Megan D Whitham
IMPORTANCE: Pregnant women are exposed to both occupational and environmental noise during their pregnancy. The association between noise and adverse health outcomes is well known. Less is known about the relationship between noise and its effects on the embryo/fetus and pregnancy. OBJECTIVES: The purpose of the study is to review what is known about the effect(s) of environment and occupational noise during pregnancy on maternal and perinatal outcomes. EVIDENCE ACQUISITION: Electronic databases (PubMed, CINAHL, and Embase) were searched from 1995-2023 with the only limitation being that the articles were in English...
April 2024: Obstetrical & Gynecological Survey
https://read.qxmd.com/read/38633420/diabetic-retinopathy-detection-using-bilayered-neural-network-classification-model-with-resubstitution-validation
#3
JOURNAL ARTICLE
Herman Khalid Omer
In recent years, eye diseases in diabetic patients are one of the most common has been diabetic retinopathy (DR). which leads to complete blindness in advanced stages. Diabetes affects the blood vessels in the retina and causes vision loss. One of the ways to decrease the risk of this issue is to detect diabetic retinopathy in its early stages. This study describes a computer-aided screening system (DREAM) that uses a neural network classification model in machine learning to assess fundus images with different illumination and fields of vision and provide a severity grade for diabetic retinopathy...
June 2024: MethodsX
https://read.qxmd.com/read/38617422/air-pollution-traffic-noise-greenness-and-temperature-and-the-risk-of-incident-type-2-diabetes-results-from-the-kora-cohort-study
#4
JOURNAL ARTICLE
Mahnaz Badpa, Alexandra Schneider, Lars Schwettmann, Barbara Thorand, Kathrin Wolf, Annette Peters
INTRODUCTION: Type 2 diabetes (T2D) is a major public health concern, and various environmental factors have been associated with the development of this disease. This study aimed to investigate the longitudinal effects of multiple environmental exposures on the risk of incident T2D in a German population-based cohort. METHODS: We used data from the KORA cohort study (Augsburg, Germany) and assessed exposure to air pollutants, traffic noise, greenness, and temperature at the participants' residencies...
April 2024: Environmental Epidemiology
https://read.qxmd.com/read/38609927/hearing-health-survey-of-the-population-in-bangkok
#5
JOURNAL ARTICLE
Suwimol Ruencharoen, Krisna Lertsukprasert, Ravin Suvanich, Jirapat Seesangnom, Mondnath Chockboondee, Wichai Aekplakorn, Chanchai Jariengprasert, Sivaporn Kiatthanabumrung, Tosapohn Wisupagan
In this cross-sectional random survey among Thai adults living in Bangkok, we aimed to identify the prevalence of hearing problems and examine their relationship with individual factors. We administered a self-report questionnaire and performed pure-tone air conduction threshold audiometry. A total of 2463 participants (1728 female individuals) aged 15-96 years were included. The hearing loss prevalence was 53.02% and increased with age. The prevalence of a moderate or greater degree of hearing impairment was 2...
April 12, 2024: BMC Public Health
https://read.qxmd.com/read/38593641/source-free-active-domain-adaptation-for-diabetic-retinopathy-grading-based-on-ultra-wide-field-fundus-images
#6
JOURNAL ARTICLE
Jinye Ran, Guanghua Zhang, Fan Xia, Ximei Zhang, Juan Xie, Hao Zhang
Domain adaptation (DA) is commonly employed in diabetic retinopathy (DR) grading using unannotated fundus images, allowing knowledge transfer from labeled color fundus images. Existing DAs often struggle with domain disparities, hindering DR grading performance compared to clinical diagnosis. A source-free active domain adaptation method (SFADA), which generates features of color fundus images by noise, selects valuable ultra-wide-field (UWF) fundus images through local representation matching, and adapts models using DR lesion prototypes, is proposed to upgrade DR diagnostic accuracy...
April 5, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38574855/evidence-based-cesarean-delivery-preoperative-management-part-7
#7
REVIEW
A Dhanya Mackeen, Maranda V Sullivan, Vincenzo Berghella
The preoperative preparation for cesarean delivery is a multistep approach for which protocols should exist at each hospital system. These protocols should be guided by the findings of this review. The interventions reviewed and recommendations made for this review have a common goal of decreasing maternal and neonatal morbidity and mortality related to cesarean delivery (CD). The preoperative time period starts prior to the patient's arrival to the hospital and ends immediately prior to skin incision. Skin cleansing in addition to CDC recommendations of showering with either soap or an antiseptic solution at least the night prior to a procedure has not been shown to further decrease rates of infection...
April 2, 2024: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/38520228/environmental-risk-factors-protective-factors-and-biomarkers-for-hearing-loss-an-umbrella-review
#8
REVIEW
Xianpeng Xu, Yiru Liao, Lihong Zhang, Yu He, Ying Zhang, Dajing Xiong, Hui Xie
OBJECTIVE: We aimed to investigate the potential environmental risk factors, protective factors, and biomarkers of hearing loss (HL), and establish a hierarchy of evidence. DATA SOURCES: Embase, PubMed, Cochrane Library, and Web of Science electronic database from inception to June 1, 2023. REVIEW METHODS: We included meta-analyses of observational studies of associations between HL and environmental risk factors, protective factors, or biomarkers...
March 23, 2024: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/38512768/mnfe-microbiome-network-flow-entropy-for-detecting-pre-disease-states-of-type-1-diabetes
#9
JOURNAL ARTICLE
Rong Gao, Peiluan Li, Yueqiong Ni, Xueqing Peng, Jing Ren, Luonan Chen
In the development of Type 1 diabetes (T1D), there are critical states just before drastic changes, and identifying these pre-disease states may predict T1D or provide crucial early-warning signals. Unlike gene expression data, gut microbiome data can be collected noninvasively from stool samples. Gut microbiome sequencing data contain different levels of phylogenetic information that can be utilized to detect the tipping point or critical state in a reliable manner, thereby providing accurate and effective early-warning signals...
2024: Gut Microbes
https://read.qxmd.com/read/38501044/cardiometabolic-diseases-according-to-the-type-and-degree-of-hearing-loss-in-noise-exposed-workers
#10
JOURNAL ARTICLE
KyooSang Kim, Sun-Haeng Choi
BACKGROUND: This study aimed to determine the association between cardiometabolic diseases, including metabolic syndrome, hypertension, and diabetes, and the type and degree of hearing loss in noise-exposed workers. METHODS: A total of 237,028 workers underwent air conduction pure tone audiometry in 2015 to assess their health and diagnose cardiometabolic diseases. The study defined metabolic syndrome, hypertension, and diabetes using blood pressure, fasting blood sugar, cholesterol, and triglyceride levels...
2024: Annals of Occupational and Environmental Medicine
https://read.qxmd.com/read/38423797/interleaved-trinuclear-mrs-for-single-session-investigation-of-carbohydrate-and-lipid-metabolism-in-human-liver-at-7t
#11
JOURNAL ARTICLE
Simone Poli, Ahmed F Emara, Naomi F Lange, Edona Ballabani, Angeline Buser, Michele Schiavon, David Herzig, Chiara Dalla Man, Lia Bally, Roland Kreis
The liver plays a central role in metabolic homeostasis, as exemplified by a variety of clinical disorders with hepatic and systemic metabolic disarrays. Of particular interest are the complex interactions between lipid and carbohydrate metabolism in highly prevalent conditions such as obesity, diabetes, and fatty liver disease. Limited accessibility and the need for invasive procedures challenge direct investigations in humans. Hence, noninvasive dynamic evaluations of glycolytic flux and steady-state assessments of lipid levels and composition are crucial for basic understanding and may open new avenues toward novel therapeutic targets...
February 29, 2024: NMR in Biomedicine
https://read.qxmd.com/read/38419242/comparison-of-effect-of-machine-muteness-to-reduce-noise-anxiety-vs-regular-settings-on-patient-compliance-during-pan-retinal-photocoagulation
#12
JOURNAL ARTICLE
Amna Anam, Irfan Qayyum Malik, Zeeshan Hameed
This Quasi Experimental study was conducted at Major Eye Clinic, Gujranwala, from January to December 2022, to study the effect of muting the sound of Argon Laser machine on patient compliance and the pain felt during pan-retinal photocoagulation (PRP). Eighty patients were included in the study with proliferative diabetic retinopathy (PDR), retinal breaks, lattice and myopic fundus degenerations for which PRP was performed. A total of 80 patients were enrolled, who were divided in two groups with 40 patients in each group...
February 2024: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/38373835/the-association-between-serum-lipid-levels-and-tinnitus-prevalence-and-severity-in-korean-elderly-a-nationwide-population-based-cross-sectional-study
#13
JOURNAL ARTICLE
Hye Jun Lee, Duk Chul Lee, Choon Ok Kim
PURPOSE: We aimed to investigate the association between serum lipid level and tinnitus risk in Korean older adults. MATERIALS AND METHODS: This study used data from the 2016-2018 Korea National Health and Nutrition Examination Survey. Overall, 6021 subjects aged ≥60 years were included. Hypertriglyceridemia was defined as a serum triglyceride level of ≥200 mg/dL. The high-risk threshold of the total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio was defined as above 5...
March 2024: Yonsei Medical Journal
https://read.qxmd.com/read/38373067/a-novel-deep-learning-model-for-diabetic-retinopathy-detection-in-retinal-fundus-images-using-pre-trained-cnn-and-hwblstm
#14
JOURNAL ARTICLE
S V Hemanth, Saravanan Alagarsamy, T Dhiliphan Rajkumar
Diabetic retinopathy (DR) is a global visual indicator of diabetes that leads to blindness and loss of vision. Manual testing presents a more difficult task when attempting to detect DR due to the complexity and variances of DR. Early detection and treatment prevent the diabetic patients from visual loss. Also classifying the intensity and levels of DR is crucial to provide necessary treatment. This study develops a novel deep learning (DL) approach called He Weighted Bi-directional Long Short-term Memory (HWBLSTM) with an effective transfer learning technique for detecting DR from the RFI...
February 19, 2024: Journal of Biomolecular Structure & Dynamics
https://read.qxmd.com/read/38359851/prediction-of-diabetes-using-data-mining-and-machine-learning-algorithms-a-cross-sectional-study
#15
JOURNAL ARTICLE
Hassan Shojaee-Mend, Farnia Velayati, Batool Tayefi, Ebrahim Babaee
OBJECTIVES: This study aimed to develop a model to predict fasting blood glucose status using machine learning and data mining, since the early diagnosis and treatment of diabetes can improve outcomes and quality of life. METHODS: This crosssectional study analyzed data from 3376 adults over 30 years old at 16 comprehensive health service centers in Tehran, Iran who participated in a diabetes screening program. The dataset was balanced using random sampling and the synthetic minority over-sampling technique (SMOTE)...
January 2024: Healthcare Informatics Research
https://read.qxmd.com/read/38321416/a-reliable-diabetic-retinopathy-grading-via-transfer-learning-and-ensemble-learning-with-quadratic-weighted-kappa-metric
#16
JOURNAL ARTICLE
Sai Venkatesh Chilukoti, Liqun Shan, Vijay Srinivas Tida, Anthony S Maida, Xiali Hei
The most common eye infection in people with diabetes is diabetic retinopathy (DR). It might cause blurred vision or even total blindness. Therefore, it is essential to promote early detection to prevent or alleviate the impact of DR. However, due to the possibility that symptoms may not be noticeable in the early stages of DR, it is difficult for doctors to identify them. Therefore, numerous predictive models based on machine learning (ML) and deep learning (DL) have been developed to determine all stages of DR...
February 6, 2024: BMC Medical Informatics and Decision Making
https://read.qxmd.com/read/38319369/exploring-the-impact-of-type-ii-diabetes-mellitus-on-voice-quality
#17
JOURNAL ARTICLE
M A Saghiri, Julia Vakhnovetsky, Mahsa Amanabi, Kasra Karamifar, Maziar Farhadi, Saeid B Amini, Michael Conte
PURPOSE: This cross-sectional study aimed to investigate the potential of voice analysis as a prescreening tool for type II diabetes mellitus (T2DM) by examining the differences in voice recordings between non-diabetic and T2DM participants. METHODS: 60 participants diagnosed as non-diabetic (n = 30) or T2DM (n = 30) were recruited on the basis of specific inclusion and exclusion criteria in Iran between February 2020 and September 2023...
February 6, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38317177/is-occupational-noise-associated-with-arthritis-cross-sectional-evidence-from-us-population
#18
JOURNAL ARTICLE
Zhounan Wu, Yuhang Liang, Ammna Khan, Jinshen He
BACKGROUND: The impact of occupational noise exposure on various diseases, including ear and cardiovascular diseases, has been studied extensively. Nevertheless, the connection between osteoarthritis (OA) and rheumatoid arthritis (RA) and occupational noise exposure remains largely unexplored in real-world scenarios. This study assessed the association between occupational noise exposure and the prevalence of two types of arthritis. METHODS: This study used database data from 2005 to 2012 and 2015-March 2020 from the prepandemic National Health and Nutrition Examination Survey (NHANES) related to occupational noise exposure and arthritis...
February 5, 2024: BMC Public Health
https://read.qxmd.com/read/38279673/analysis-of-microvascular-pattern-in-diabetes-mellitus-condition-using-the-nailfold-capillaroscopy-images
#19
JOURNAL ARTICLE
Sowmiya Elumalai, Nirmala Krishnamoorthi, Naveen Periyasamy, Mohamed Farazullah, Kiran Raj, Shriraam Mahadevan
Diabetes is often considered a vascular disease due to its impact on blood vessels, it is a complex condition with various metabolic and autoimmune factors involved. One of the long term comorbidities of diabetes includes microvascular complications. The microvascular complications can be analyzed using the Nailfold capillaroscopy, a non-invasive technique that allows for the visualization and analysis of capillaries in the proximal nailfold area. Using advanced video capillaroscopy with high magnification, capillary images can be captured from and processed to analyze their morphology...
January 27, 2024: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://read.qxmd.com/read/38248277/effect-of-magnetic-resonance-image-quality-on-structural-and-functional-brain-connectivity-the-maastricht-study
#20
JOURNAL ARTICLE
Joost J A de Jong, Jacobus F A Jansen, Laura W M Vergoossen, Miranda T Schram, Coen D A Stehouwer, Joachim E Wildberger, David E J Linden, Walter H Backes
In population-based cohort studies, magnetic resonance imaging (MRI) is vital for examining brain structure and function. Advanced MRI techniques, such as diffusion-weighted MRI (dMRI) and resting-state functional MRI (rs-fMRI), provide insights into brain connectivity. However, biases in MRI data acquisition and processing can impact brain connectivity measures and their associations with demographic and clinical variables. This study, conducted with 5110 participants from The Maastricht Study, explored the relationship between brain connectivity and various image quality metrics (e...
January 8, 2024: Brain Sciences
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