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Pollution and diabet

Stacey E Alexeeff, Ananya Roy, Jun Shan, Xi Liu, Kyle Messier, Joshua S Apte, Christopher Portier, Stephen Sidney, Stephen K Van Den Eeden
BACKGROUND: Some studies have linked long-term exposure to traffic related air pollutants (TRAP) with adverse cardiovascular health outcomes; however, previous studies have not linked highly variable concentrations of TRAP measured at street-level within neighborhoods to cardiovascular health outcomes. METHODS: Long-term pollutant concentrations for nitrogen dioxide [NO2 ], nitric oxide [NO], and black carbon [BC] were obtained by street-level mobile monitoring on 30 m road segments and linked to residential addresses of 41,869 adults living in Oakland during 2010 to 2015...
May 15, 2018: Environmental Health: a Global Access Science Source
Rajiv Janardhanan
The latter half of the twentieth century has witnessed a humongous spurt in the use of synthetic chemicals in a wide variety of industrial and agricultural applications are leading to niche specific perturbations affecting every trophic level of the ecosystems due to unmitigated environmental contamination. Despite the incremental usefulness of endocrine disrupting chemicals (EDCs) such as pesticides and plasticizers, their statutory impact on environmental health is assuming worrisome proportions. The EDCs can disrupt physiological homeostasis resulting in developmental and reproductive abnormalities...
May 14, 2018: Current Drug Targets
Patrick D M C Katoto, Friedrich Thienemann, André N H Bulabula, Tonya M Esterhuizen, Aimé B Murhula, Pierre P M Lunjwire, Dieudonné M Bihehe, Jean B Nachega
OBJECTIVE: To determine the prevalence of and risk factors for metabolic syndrome (MS) in HIV-infected adults at three urban clinics in Bukavu, Democratic Republic of the Congo. DESIGN: Cross-sectional study. METHODS: From July to September 2016, baseline socio-demographics, risk factors, and clinical characteristics were collected using a structured questionnaire or extracted from medical records. Fasting blood sugar and lipids were measured...
May 12, 2018: Tropical Medicine & International Health: TM & IH
Ralph Chapman, Michael Keall, Philippa Howden-Chapman, Mark Grams, Karen Witten, Edward Randal, Alistair Woodward
Active travel (walking and cycling) is beneficial for people’s health and has many co-benefits, such as reducing motor vehicle congestion and pollution in urban areas. There have been few robust evaluations of active travel, and very few studies have valued health and emissions outcomes. The ACTIVE before-and-after quasi-experimental study estimated the net benefits of health and other outcomes from New Zealand’s Model Communities Programme using an empirical analysis comparing two intervention cities with two control cities...
May 11, 2018: International Journal of Environmental Research and Public Health
Wei-Shan Chin, Yu-Kang Chang, Li-Feng Huang, Hung-Chang Tsui, Chih-Cheng Hsu, Yue-Liang Leon Guo
OBJECTIVE: No study has examined the effects of air pollutants on albuminuria in type 2 diabetes. Therefore, the present study investigated this association. METHODS: This follow-up study enrolled 812 patients with type 2 diabetes between 2003 and 2012. The urinary albumin-to-creatinine ratio (ACR) was recorded annually. Exposure to the air pollutants CO, NO2 , O3 , SO2 , and PM2.5 was interpolated from 72 air-quality monitoring stations to residences by using the kriging method...
April 23, 2018: International Journal of Hygiene and Environmental Health
Mathew Joseph Valamparampil, Ananth Mohan, Chinu Jose, Deepthi Kottassery Sadheesan, Jemin Jose Aby, Prasannakumar Vasudevakaimal, Sara Varghese, Anish Tekkumkara Surendrannair, Achu Laila Ashokan, Resmi Santhakumari Madhusoodhanan, Insija Selene Ilyas, Amjith Rajeevan, Sreekanth Balakrishnan Karthikeyan, Krishna Sulochana Devadhas, Rajesh Raghunath, Sethulekshmi Surendran, Harikrishnan Muraleedharanpillai, Zinia Thajudeen Nujum
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the world. The determinants of CVD in an urban population using conventional and geographic information system techniques were attempted as a community-based census-type cross-sectional study in Kerala, India, among 1649 individuals residing in 452 households. Sociodemographic details, risk factor exposures, and self-reported disease prevalence were determined. Location of houses, wells from which subjects drew drinking water, and distances of the house from the outer road (proxy for air pollution) were mapped using differential global positioning system and pH of water samples determined...
April 1, 2018: Asia-Pacific Journal of Public Health
Sarah A Lucht, Frauke Hennig, Clara Matthiessen, Simone Ohlwein, Andrea Icks, Susanne Moebus, Karl-Heinz Jöckel, Hermann Jakobs, Barbara Hoffmann
BACKGROUND: Despite the importance of understanding the connection between air pollution exposure and diabetes, studies investigating links between air pollution and glucose metabolism in nondiabetic adults are limited. OBJECTIVE: We aimed to estimate the association of medium-term air pollution exposures with blood glucose and glycated hemoglobin A1c (HbA1c) among nondiabetics. METHODS: This study included observations from nondiabetic participants (nobs =7,108) of the population-based Heinz Nixdorf Recall study at baseline (2000–2003) and follow-up examination (2006–2008)...
April 3, 2018: Environmental Health Perspectives
Bo-Yi Yang, Zhengmin Min Qian, Shanshan Li, Gongbo Chen, Michael S Bloom, Michael Elliott, Kevin W Syberg, Joachim Heinrich, Iana Markevych, Si-Quan Wang, Da Chen, Huimin Ma, Duo-Hong Chen, Yimin Liu, Mika Komppula, Ari Leskinen, Kang-Kang Liu, Xiao-Wen Zeng, Li-Wen Hu, Yuming Guo, Guang-Hui Dong
BACKGROUND: Health effects of air pollution on diabetes have been scarcely studied in developing countries. We aimed to explore the associations of long-term exposure to ambient particulate matter (PM) and gaseous pollutants with diabetes prevalence and glucose-homoeostasis markers in China. METHODS: Between April 1 and Dec 31, 2009, we recruited a total of 15 477 participants aged 18-74 years using a random number generator and a four-staged, stratified and cluster sampling strategy from a large cross-sectional study (the 33 Communities Chinese Health Study) from three cities in Liaoning province, northeastern China...
February 2018: Lancet. Planetary Health
Angel M Dzhambov
No abstract text is available yet for this article.
February 2018: Lancet. Planetary Health
John Baptist Nzukizi Mudumbi, Seteno Karabo Obed Ntwampe, Lukhanyo Mekuto, Tandi Matsha, Elie Fereche Itoba-Tombo
Type 2 diabetes mellitus (T2DM) is the most common form of diabetes and it is characterized by high blood sugar and abnormal sera lipid levels. Although the specific reasons for the development of these abnormalities are still not well understood, traditionally, genetic and lifestyle behavior have been reported as the leading causes of this disease. In the last three decades, the number of diabetic patients has drastically increased worldwide, with current statistics suggesting the number is to double in the next two decades...
April 2, 2018: Environmental Monitoring and Assessment
Minzhen Wang, Shan Zheng, Yonghong Nie, Jun Weng, Ning Cheng, Xiaobin Hu, Xiaowei Ren, Hongbo Pei, Yana Bai
Air pollution exposure may play an adverse role in diabetes. However, little data are available directly evaluating the effects of air pollution exposure in blood lipids of which dysfunction has been linked to diabetes or its complications. We aimed to evaluate the association between air pollution and lipids level among type 2 diabetic patients in Northwest China. We performed a population-based study of 3912 type 2 diabetes patients in an ongoing cohort study in China. Both spline and multiple linear regressions analysis were used to examine the association between short-term exposure to PM10 , SO₂, NO₂ and total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C)...
March 30, 2018: International Journal of Environmental Research and Public Health
Buddha Basnyat, Maxine Caws, Zarir Udwadia
Background: Tuberculosis (TB) remains the most common cause of infectious disease deaths worldwide. What is perhaps less appreciated is that the caseload of tuberculosis patients in South Asia is staggering.South Asia has almost 40% of the global TB burden with 4,028,165 cases in 2015. This region also has a disproportionate share of TB deaths (681,975 deaths, 38% of the global burden). Worldwide just 12.5% of TB cases are in HIV positive individuals, but much research and investment has focused on HIV-associated TB...
2018: Multidisciplinary Respiratory Medicine
Olanrewaju I Fatola, Francis A Olaolorun, Funmilayo E Olopade, James O Olopade
Vanadium, atomic number 23, is a transition metal widely distributed in nature. It is a major contaminant of fossil fuels and is widely used in industry as catalysts, in welding, and making steel alloys. Over the years, vanadium compounds have been generating interests due to their use as therapeutic agents in the control of diabetes, tuberculosis, and some neoplasms. However, the toxicity of vanadium compounds is well documented in literature with occupational exposure of workers in vanadium allied industries, environmental pollution from combustion of fossil fuels and industrial exhausts receiving concerns as major sources of toxicity and a likely predisposing factor in the aetiopathogenesis of neurodegenerative diseases...
March 22, 2018: Brain Research Bulletin
Stephanie T Grady, Petros Koutrakis, Jaime E Hart, Brent A Coull, Joel Schwartz, Francine Laden, Junfeng Jim Zhang, Jicheng Gong, Marilyn L Moy, Eric Garshick
OBJECTIVES: We assessed relationships between indoor black carbon (BC) exposure and urinary oxidative stress biomarkers, 8-hydroxy-2'-deoxyguanosine (8-OHdG) and malondialdehyde (MDA), in participants with chronic obstructive pulmonary disease (COPD). METHODS: Eighty-two participants completed in-home air sampling for one week prior to providing urine samples up to four times in a year. Weekly indoor and daily outdoor concentrations were used to estimate indoor daily lags and moving averages...
March 22, 2018: Environment International
Daniela Caccamo, Sergio Ricca, Monica Currò, Riccardo Ientile
Hypovitaminosis D has become a pandemic, being observed in all ethnicities and age groups worldwide. Environmental factors, such as increased air pollution and reduced ultraviolet B (UVB) irradiation, as well as lifestyle factors, i.e., decreased outdoor activities and/or poor intake of vitamin D-rich food, are likely involved in the etiology of a dramatic reduction of vitamin D circulating levels. The insufficiency/deficiency of vitamin D has long been known for its association with osteoporosis and rickets...
March 17, 2018: International Journal of Molecular Sciences
Lesya Marushka, Xuefeng Hu, Malek Batal, Tonio Sadik, Harold Schwartz, Amy Ing, Karen Fediuk, Constantine Tikhonov, Hing Man Chan
We previously studied the association between fish consumption and prevalence of type 2 diabetes (T2D) in Manitoba and Ontario First Nations (FNs), Canada and found different results. In this study, we used a difference in difference model to analyze the data. Dietary and health data from the First Nations Food Nutrition and Environment Study, a cross-sectional study of 706 Manitoba and 1429 Ontario FNs were analyzed. The consumption of fish was estimated using a food frequency questionnaire. Fish samples were analyzed for dichloro diphenyldichloro ethylene (DDE) and polychlorinated biphenyls (PCBs) content...
March 17, 2018: International Journal of Environmental Research and Public Health
Vanesa Bellou, Lazaros Belbasis, Ioanna Tzoulaki, Evangelos Evangelou
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a global epidemic associated with increased health expenditure, and low quality of life. Many non-genetic risk factors have been suggested, but their overall epidemiological credibility has not been assessed. METHODS: We searched PubMed to capture all meta-analyses and Mendelian randomization studies for risk factors of T2DM. For each association, we estimated the summary effect size, its 95% confidence and prediction interval, and the I2 metric...
2018: PloS One
Marnie F Hazlehurst, Paula S Nurius, Anjum Hajat
Psychosocial and environmental stress exposures across the life course have been shown to be relevant in the development of cardiovascular disease (CVD). Assessing more than one stressor from different domains (e.g., individual and neighborhood) and across the life course moves us towards a more integrated picture of how stress affects health and well-being. Furthermore, these individual and neighborhood psychosocial stressors act on biologic pathways, including immune function and inflammatory response, which are also impacted by ubiquitous environmental exposures such as air pollution...
March 8, 2018: International Journal of Environmental Research and Public Health
Stefanie Lanzinger, Joachim Rosenbauer, Dorothea Sugiri, Tamara Schikowski, Birgit Treiber, Daniela Klee, Wolfgang Rathmann, Reinhard W Holl
AIMS/HYPOTHESIS: Studies on the association between air pollution and metabolic control in children and adolescents with type 1 diabetes are rare and findings are inconsistent. We examined the relationship between air pollution variables (particulate matter with an aerodynamic diameter <10 μm [PM10 ], NO2 and accumulated ozone exposure [O3 -AOT]) and metabolic variables (HbA1c and daily insulin dose [U/kg body weight]) in children and adolescents with type 1 diabetes. METHODS: We investigated 37,372 individuals with type 1 diabetes aged <21 years, documented between 2009 and 2014 in 344 German centres of the prospective diabetes follow-up registry (Diabetes-Patienten-Verlaufsdokumentation [DPV])...
June 2018: Diabetologia
Geng Zong, Damaskini Valvi, Brent Coull, Thomas Göen, Frank B Hu, Flemming Nielsen, Philippe Grandjean, Qi Sun
BACKGROUND: Exposure to persistent organic pollutants (POPs) may predispose to the development of type 2 diabetes (T2D), but prospective human evidence is scarce. OBJECTIVES: We investigated the association between plasma-POP concentrations in the late 1990s and incident T2D over 11 years of follow-up in the Nurses' Health Study II. DISCUSSION: Three organochlorine pesticides and 20 polychlorinated biphenyls (PCBs) were measured in banked plasma from 793 case-control pairs of T2D...
May 2018: Environment International
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