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Pollution and diabet

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https://www.readbyqxmd.com/read/29346078/long-term-high-air-pollution-exposure-induced-metabolic-adaptations-in-traffic-policemen
#1
Chaochao Tan, Yupeng Wang, Mingyue Lin, Zhu Wang, Li He, Zhiyi Li, Yu Li, Keqian Xu
OBJECTIVE: To assess the adverse physiological changes induced by long-term exposure to PM2.5. METHODS: Totally 183 traffic policemen and 88 office policemen as the control group, were enrolled in this study. The concentrations of PM2.5 in both the working places of traffic and office policemen were obtained. Detailed personal questionnaires and conventional laboratory tests including hematology, fasting blood glucose, blood lipids, liver, kidney, immunity and tumor-related markers were conducted on all participants of this study...
January 5, 2018: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29342195/association-between-pm10-pm2-5-no2-o3-and-self-reported-diabetes-in-italy-a-cross-sectional-ecological-study
#2
Riccardo Orioli, Giuseppe Cremona, Luisella Ciancarella, Angelo G Solimini
INTRODUCTION: Air pollution represents a serious threat to health on a global scale, being responsible for a large portion of the global burden of disease from environmental factors. Current evidence about the association between air pollution exposure and Diabetes Mellitus (DM) is still controversial. We aimed to evaluate the association between area-level ambient air pollution and self-reported DM in a large population sample in Italy. MATERIALS AND METHODS: We extracted information about self-reported and physician diagnosed DM, risk factors and socio-economic status from 12 surveys conducted nationwide between 1999 and 2013...
2018: PloS One
https://www.readbyqxmd.com/read/29329571/environmental-exposures-and-fetal-growth-the-haifa-pregnancy-cohort-study
#3
Rachel Golan, Itai Kloog, Ronit Almog, Anat Gesser-Edelsburg, Maya Negev, Maya Jolles, Varda Shalev, Vered H Eisenberg, Gideon Koren, Wiessam Abu Ahmad, Hagai Levine
BACKGROUND: The developing fetus is susceptible to environmental insults. Studying the effects of environmental exposures on fetal growth is essential for understanding the causal pathway between prenatal exposures and pregnancy outcomes. Here we describe the Haifa Pregnancy Cohort Study (HPCS) and discuss challenges and opportunities in applying "big data" paradigm. METHODS: Maccabi Healthcare Services (MHS), is the second largest Israeli health maintenance organization (HMO) providing care services to two million beneficiaries...
January 12, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29319630/exposure-to-ambient-ultrafine-particles-and-nitrogen-dioxide-and-incident-hypertension-and-diabetes
#4
Li Bai, Hong Chen, Marianne Hatzopoulou, Michael Jerrett, Jeffrey C Kwong, Richard T Burnett, Aaron van Donkelaar, Ray Copes, Randall V Martin, Keith van Ryswyk, Hong Lu, Alexander Kopp, Scott Weichenthal
BACKGROUND: Previous studies reported that long-term exposure to traffic-related air pollution may increase the incidence of hypertension and diabetes. However, little is known about the associations of ultrafine particles (≤0.1 micrometers in diameter) with these two conditions. METHODS: We conducted a population-based cohort study to investigate the associations between exposures to ultrafine particles and nitrogen dioxide (NO2) and the incidence of diabetes and hypertension...
January 9, 2018: Epidemiology
https://www.readbyqxmd.com/read/29304014/environmental-risk-factors-for-developing-type-2-diabetes-mellitus-a-systematic-review
#5
REVIEW
Tashi Dendup, Xiaoqi Feng, Stephanie Clingan, Thomas Astell-Burt
Different elements of the environment have been posited to influence type 2 diabetes mellitus (T2DM). This systematic review summarizes evidence on the environmental determinants of T2DM identified in four databases. It proposes a theoretical framework illustrating the link between environment and T2DM, and briefly discusses some methodological challenges and potential solutions, and opportunities for future research. Walkability, air pollution, food and physical activity environment and roadways proximity were the most common environmental characteristics studied...
January 5, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29261145/maternal-exposure-to-air-pollutants-and-risk-of-gestational-diabetes-mellitus-in-taiwan
#6
Hsiu-Nien Shen, Sheng-Yuan Hua, Chang-Ta Chiu, Chung-Yi Li
Mounting evidence has shown an increased risk of gestational diabetes mellitus (GDM) in association with elevated exposure to air pollution. However, limited evidence is available concerning the effect of specific air pollutant(s) on GDM incidence. We conducted this case-control study on 6717 mothers with GDM diagnosed in 2006-2013 and 6717 age- and year of delivery-matched controls to further address the risk of GDM in relation to specific air pollutant. Both cases and controls were selected from a cohort of 1-million beneficiaries of Taiwan's National Health Insurance program registered in 2005...
December 20, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29258957/decreased-macrophage-phagocytic-function-due-to-xenobiotic-exposures-in-vitro-difference-in-sensitivity-between-various-macrophage-models
#7
Hanne Friis Berntsen, Anette Kocbach Bølling, Cesilie Granum Bjørklund, Karin Zimmer, Erik Ropstad, Shanbeh Zienolddiny, Rune Becher, Jørn A Holme, Hubert Dirven, Unni Cecilie Nygaard, Johanna Bodin
Both autoimmune disease prevalence and exposure to immunotoxic chemicals have increased the last decades. As a first screening of immunotoxic chemicals possibly affecting development of autoimmunity through attenuated macrophage function, we demonstrate a promising model measuring macrophage function in isolated peritoneal macrophages (PCM) from Wistar rats and C57Bl/6 mice. Immunotoxic effects of bisphenol A (BPA) and a selection of perfluoroalkyl acids (PFAAs) were analysed in vitro assessing phagocytic function of macrophages from different sources...
December 16, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29248851/traffic-related-air-pollution-associated-with-chronic-kidney-disease-among-elderly-residents-in-taipei-city
#8
Szu-Ying Chen, Da-Chen Chu, Jui-Huan Lee, Ya-Ru Yang, Chang-Chuan Chan
The associations of air pollution with chronic kidney disease (CKD) have not yet been fully studied. We enrolled 8,497 Taipei City residents older than 65 years and calculated the estimated glomerular filtration rate (eGFR) using the Taiwanese Chronic Kidney Disease Epidemiology Collaboration equation. Proteinuria was assessed via dipstick on voided urine. CKD prevalence and risk of progression were defined according to the KDIGO 2012 guidelines. Land-use regression models were used to estimate the participants' one-year exposures to PM of different sizes and traffic-related exhaust, PM2...
December 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29227885/neighbourhood-social-and-physical-environment-and-general-practitioner-assessed-morbidity
#9
Peter P Groenewegen, Jan-Paul Zock, Peter Spreeuwenberg, Marco Helbich, Gerard Hoek, Annemarie Ruijsbroek, Maciej Strak, Robert Verheij, Beate Volker, Geeke Waverijn, Martin Dijst
The aim of our study was to investigate the association between health enhancing and threatening, and social and physical aspects of the neighbourhood environment and general practitioner (GP) assessed morbidity of the people living there, in order to find out whether the effects of environmental characteristics add up or modify each other. We combined GP electronic health records with environmental data on neighbourhoods in the Netherlands. Cross-classified logistic multilevel models show the importance of taking into account several environmental characteristics and confounders, as social capital effects on the prevalence of morbidity disappear when other area characteristics are taken into account...
December 8, 2017: Health & Place
https://www.readbyqxmd.com/read/29220800/exposure-to-traffic-related-air-pollution-and-the-composition-of-the-gut-microbiota-in-overweight-and-obese-adolescents
#10
Tanya L Alderete, Roshonda B Jones, Zhanghua Chen, Jeniffer S Kim, Rima Habre, Frederick Lurmann, Frank D Gilliland, Michael I Goran
BACKGROUND: Traffic-related air pollution (TRAP) exposure has been linked to type 2 diabetes and metabolic dysfunction in humans. Animal studies suggest that air pollutants may alter the composition of the gut microbiota, which may negatively impact metabolic health through changes in the composition and/or function of the gut microbiome. OBJECTIVES: The primary aim of this study was to determine whether elevated TRAP exposure was correlated with gut bacterial taxa in overweight and obese adolescents from the Meta-AIR (Metabolic and Asthma Incidence Research) study...
December 5, 2017: Environmental Research
https://www.readbyqxmd.com/read/29212347/oxidative-stress-a-unifying-mechanism-for-cell-damage-induced-by-noise-water-pipe-smoking-and-emotional-stress-therapeutic-strategies-targeting-redox-imbalance
#11
Saeid Golbidi, Huige Li, Ismail Laher
SIGNIFICANCE: Modern technologies have eased our lives but these conveniences can impact our lifestyles in destructive ways. Noise pollution, mental stresses, and smoking (as a stress-relieving solution) are some environmental hazards which affect our well-being and health care budgets. Scrutinizing their pathophysiology could lead to solutions to reduce their harmful effects. Recent advances: Oxidative stress plays an important role in initiating local and systemic inflammation following noise pollution, mental stress, and smoking...
December 6, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29194408/exposure-to-night-time-traffic-noise-melatonin-regulating-gene-variants-and-change-in-glycemia-in-adults
#12
Ikenna C Eze, Medea Imboden, Maria Foraster, Emmanuel Schaffner, Ashish Kumar, Danielle Vienneau, Harris Héritier, Franziska Rudzik, Laurie Thiesse, Reto Pieren, Arnold von Eckardstein, Christian Schindler, Mark Brink, Jean-Marc Wunderli, Christian Cajochen, Martin Röösli, Nicole Probst-Hensch
Traffic noise has been linked to diabetes, with limited understanding of its mechanisms. We hypothesize that night-time road traffic noise (RTN) may impair glucose homeostasis through circadian rhythm disturbances. We prospectively investigated the relationship between residential night-time RTN and subsequent eight-year change in glycosylated hemoglobin (ΔHbA1c) in 3350 participants of the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA), adjusting for diabetes risk factors and air pollution levels...
December 1, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29178978/the-association-between-exposure-to-air-pollutants-including-pm10-pm2-5-ozone-carbon-monoxide-sulfur-dioxide-and-nitrogen-dioxide-concentration-and-the-relative-risk-of-developing-stemi-a-case-crossover-design
#13
Mohammad Ali Akbarzadeh, Isa Khaheshi, Amirsina Sharifi, Negin Yousefi, Mohammadreza Naderian, Mohammad Hasan Namazi, Morteza Safi, Hossein Vakili, Habibollah Saadat, Saeed Alipour Parsa, Negin Nickdoost
BACKGROUND: Unfavorable associations between air pollution and myocardial infarction are broadly investigated in recent studies and some of them revealed considerable associations; however, controversies exists between these investigations with regard to culprit components of air pollution and significance of correlation between myocardial infarction risk and air pollution. METHODS: The association between exposure to PM10, PM2.5, ozone, carbon monoxide, sulfur dioxide, and nitrogen dioxide concentration of background air that residents of Tehran, the capital city of Iran, which is ranked as the most air polluted city of Iran and the relative risk of developing ST-elevation myocardial infarction (STEMI) were investigated by a case-crossover design...
November 24, 2017: Environmental Research
https://www.readbyqxmd.com/read/29161632/ambient-air-pollution-adipokines-and-glucose-homeostasis-the-framingham-heart-study
#14
Wenyuan Li, Kirsten S Dorans, Elissa H Wilker, Mary B Rice, Itai Kloog, Joel D Schwartz, Petros Koutrakis, Brent A Coull, Diane R Gold, James B Meigs, Caroline S Fox, Murray A Mittleman
OBJECTIVE: To examine associations of proximity to major roadways, sustained exposure to fine particulate matter (PM2.5), and acute exposure to ambient air pollutants with adipokines and measures of glucose homeostasis among participants living in the northeastern United States. METHODS: We included 5958 participants from the Framingham Offspring cohort examination cycle 7 (1998-2001) and 8 (2005-2008) and Third Generation cohort examination cycle 1 (2002-2005) and 2 (2008-2011), who did not have type 2 diabetes at the time of examination visit...
November 18, 2017: Environment International
https://www.readbyqxmd.com/read/29160704/nanobiotechnology-for-environment-innovative-solutions-for-the-management-of-harmful-algal-blooms
#15
Matthew Robert Gellert, Beum Jun Kim, Samuel Evan Reffsin, Sebastian Eureko Jusuf, Nicole Denise Wagner, Stephen Winans, Mingming Wu
Nanobiotechnology has played important roles in solving contemporary health problems including cancer and diabetes, but has not yet been widely exploited for problems in food security and environmental protection. Water scarcity is an emerging worldwide problem due to climate change and population increase. Current methods of managing water resources are not efficient or sustainable. In this perspective, we focus on harmful algal blooms to demonstrate how nanobiotechnology can be explored to understand microbe-environment interaction and allow for toxin/pollutant detection with significantly improved sensitivity...
November 21, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29142003/disparities-in-environmental-exposures-to-endocrine-disrupting-chemicals-and-diabetes-risk-in-vulnerable-populations
#16
Daniel Ruiz, Marisol Becerra, Jyotsna S Jagai, Kerry Ard, Robert M Sargis
Burgeoning epidemiological, animal, and cellular data link environmental endocrine-disrupting chemicals (EDCs) to metabolic dysfunction. Disproportionate exposure to diabetes-associated EDCs may be an underappreciated contributor to disparities in metabolic disease risk. The burden of diabetes is not uniformly borne by American society; rather, this disease disproportionately affects certain populations, including African Americans, Latinos, and low-income individuals. The purpose of this study was to review the evidence linking unequal exposures to EDCs with racial, ethnic, and socioeconomic diabetes disparities in the U...
November 15, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29118034/cardiovascular-effects-of-long-term-exposure-to-air-pollution-a-population-based-study-with-900%C3%A2-845%C3%A2-person-years-of-follow-up
#17
Hyeanji Kim, Joonghee Kim, Sunhwa Kim, Si-Hyuck Kang, Hee-Jun Kim, Ho Kim, Jongbae Heo, Seung-Muk Yi, Kyuseok Kim, Tae-Jin Youn, In-Ho Chae
BACKGROUND: Studies have shown that long-term exposure to air pollution such as fine particulate matter (≤2.5 μm in aerodynamic diameter [PM2.5]) increases the risk of all-cause and cardiovascular mortality. To date, however, there are limited data on the impact of air pollution on specific cardiovascular diseases. This study aimed to evaluate cardiovascular effects of long-term exposure to air pollution among residents of Seoul, Korea. METHODS AND RESULTS: Healthy participants with no previous history of cardiovascular disease were evaluated between 2007 and 2013...
November 8, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29118024/arsenic-exposure-induces-glucose-intolerance-and-alters-global-energy-metabolism
#18
Andrew G Kirkley, Christopher M Carmean, Daniel Ruiz, Honggang Ye, Shane M Regnier, Ananta Poudel, Manami Hara, Wakanene Kamau, Daniel N Johnson, Austin A Roberts, Patrick J Parsons, Susumu Seino, Robert Michael Sargis
Environmental pollutants acting as endocrine disrupting chemicals (EDCs) are recognized as potential contributors to metabolic disease pathogenesis. One such pollutant, arsenic, contaminates the drinking water of approximately 100 million people globally and has been associated with insulin resistance and diabetes in epidemiological studies. Despite these observations, the precise metabolic derangements induced by arsenic remain incompletely characterized. In the present study, arsenic's impact on in vivo metabolic physiology was examined in 8 week old male C57BL/6J mice exposed to 50 mg/L inorganic arsenite in their drinking water for 8 weeks...
November 8, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29117118/diet-and-asthma-is-it-time-to-adapt-our-message
#19
REVIEW
Laurent Guilleminault, Evan J Williams, Hayley A Scott, Bronwyn S Berthon, Megan Jensen, Lisa G Wood
Asthma is a chronic respiratory disorder which is associated with airway inflammation. Environmental factors, in association with genetic susceptibility, play a critical role in asthma pathophysiology. Inhaled allergens, smoke exposure, indoor and outdoor air pollution are common triggers of asthma symptoms. Although the role of diet has clearly established mechanisms in diseases such as cardiovascular disease, type 2 diabetes, and cancer, it is not commonly identified as a causal factor in asthma. However, some dietary patterns, such as the Western diet, which includes a high intake of refined grains, processed and red meats, and desserts, have pro-inflammatory effects...
November 8, 2017: Nutrients
https://www.readbyqxmd.com/read/29111283/pancreatic-islet-autonomous-effect-of-arsenic-on-insulin-secretion-through-endoplasmic-reticulum-stress-autophagy-pathway
#20
Wei Wu, Xiaofeng Yao, Liping Jiang, Qiaoting Zhang, Jie Bai, Tianming Qiu, Lei Yang, Ni Gao, Guang Yang, Xiaofang Liu, Min Chen, Xiance Sun
Inorganic arsenic is a worldwide environmental pollutant. Arsenic's relationship with the incidence of diabetes arouses concerns on its etiological mechanism. In this study, the glucose-stimulated insulin secretion (GSIS) from isolated pancreatic islets of As2O3-treated mice was significantly lower than that of control mice. It indicated that the effect of As2O3-inhibited GSIS was pancreatic islet-autonomous. The level of phospho-PERK (p-PERK), a biomarker of endoplasmic reticulum (ER) stress, in pancreas of As2O3-treated mice was increased significantly...
October 27, 2017: Food and Chemical Toxicology
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