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Attila Nemes, Kálmán Havasi, Nóra Ambrus, Mária Kohári, László Sághy, Tamás Forster
Left atrial appendage is a cardiac chamber in variable shapes and sizes. Its condition is associated with atrial arrhytmias and the presence of a thrombus. Due to its difficult visualisation, the present review aimed to demonstrate the role of different echocardiographic methods in its assessment. Orv Hetil. 2018; 159(9): 335-345.
March 2018: Orvosi Hetilap
Duccio Di Carlo, Bruno Marino
No abstract text is available yet for this article.
March 1, 2018: International Journal of Cardiology
Michela Casella, Valentina Ribatti, Valentina Catto, Giulia Vettor, Gaetano Fassini, Viviana Biagioli, Antonio Dello Russo, Claudio Tondo
Electrophysiology procedures are traditionally performed under fluoroscopic guidance. Nowadays a growing interest in the radiation risk associated to these procedures has been cultivated, since radiation exposure has non-neglegible stochastic and deterministic effects on health. A correlation between radiation exposure and lifetime malignancy effect is difficult to establish and the threshold of a completely safe exposure dose is unknown. Thus, electrophisiologists have become aware of the use of fluoroscopy and they have tried to use all the complementary imaging technologies available in order to reduce the radiological exposure...
August 31, 2017: Minerva Cardioangiologica
Erick A Perez Alday, Michael A Colman, Philip Langley, Henggui Zhang
Atrial tachy-arrhytmias, such as atrial fibrillation (AF), are characterised by irregular electrical activity in the atria, generally associated with erratic excitation underlain by re-entrant scroll waves, fibrillatory conduction of multiple wavelets or rapid focal activity. Epidemiological studies have shown an increase in AF prevalence in the developed world associated with an ageing society, highlighting the need for effective treatment options. Catheter ablation therapy, commonly used in the treatment of AF, requires spatial information on atrial electrical excitation...
March 2017: PLoS Computational Biology
Zdeňka Límanová, Jan Jiskra
Cardiovascular system is essentially affected by thyroid hormones by way of their genomic and non-genomic effects. Untreated overt thyroid dysfunction is associated with higher cardiovascular risk. Although it has been studied more than 3 decades, in subclinical thyroid dysfunction the negative effect on cardiovascular system is much more controversial. Large meta-analyses within last 10 years have shown that subclinical hyperthyroidism is associated with higher cardiovascular risk than subclinical hypothyroidism...
December 0: Vnitr̆ní Lékar̆ství
Katarzyna Foryś, Mariusz Foryś, Katarzyna Piotrowicz
The obstructive sleep apnea (OSA) is a mortality risk factor of the cardiovascular system diseases. One of the elements of this relationship is the occurrence of nocturnal cardiac arrhythmias. The arrhytmias in question are resistant to drug therapy so it is suggested to consider electrotherapy. However, the coexistence of OSA and thus recurrent episodes of nocturnal hypoxia, may have significant impact on the diagnosis and the treatment applied as shown in the following cases. In some cases, the decision of electrotherapy should be preceded by the use of therapy with continuous positive airway pressure (CPAP)...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Emanuele Cecchi, Francesco Grossi, Matteo Rossi, Cristina Giglioli, Maria Laura De Feo
Hypocalcemia is frequent in the setting of endocrine disorders, bone diseases and renal failure. When hypocalcemia is severe it can predispose to life-threatening ventricular arrhythmias; in such cases a rapid admission to hospital and a prompt correction of electrolyte imbalance are needed. We report the case of an old patient suffering from renal failure that was admitted to our cardiac step-down unit because of severe hypocalcemia associated with ventricular arrhythmias. Hypocalcemia was promptly treated and an endocrinologic consult was requested for investigating the causes of this electrolyte imbalance...
September 2015: Clinical Cases in Mineral and Bone Metabolism
Valentina D A Corino, Simone Monacizzo, Roberto Sassi, Luca T Mainardi, Juan Pablo Martinez
Implantable cardioverter defibrillators (ICD) are the most effective way of preventing sudden cardiac death (SCD). However, the implantation of an ICD is an invasive procedure with associated risks and a high cost. Therefore, it is necessary to determine non-invasive risk markers that identify patients at a higher risk of suffering malignant arrhytmias. One of the most promising non-invasive indices is T-wave alternans (TWA). This work assesses T-wave alternans using the Amplitude of Dominant T-Wave Alternans (ADTWA), that is derived from the dominant T wave associated to a number of consecutive beats...
August 2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Petr Tomášek, Petra Dohnalová, Tereza Kubíková, Milena Králíčková, Michal Beran, Zbyněk Tonar
Arrhythmogenic ventricular cardiomyopathy is considered to be a primary cardiomyopathy. Over the last few decades, although being a relatively rare disease with its prevalence 1:2000 - 1:5000, there were numerous studies performed with the aim to elucidate the underlaying causes, pathogenesis, diagnostical aspects and possible treatment options of the disease. Arrhythmogenic ventricular cardiomyopathy is genetically conditioned disease where proteins of the cell-cell junctions are involved. Mutations of the myocardial intercalated dics proteins, mainly desmosomal proteins (e...
2015: Soudní Lékarství
Erzsébet Rőth
The reperfusion of acute ischaemic myocardium is essential for myocardial salvage, so-called "gold standard" therapy, however it can result in serious damage to the myocardium. Functional alterations occur, including depressed contractile function and decreased coronary flow as well as altered vascular reactivity. Over several decades it has been demonstrated that oxygen radical formation is greatly increased in the post-ischaemic heart and serves as a critical central mechanism of ischaemic-reperfusion injury...
November 22, 2015: Orvosi Hetilap
Jan Matějka, Ivo Varvařovský, Vladimír Rozsíval, Aleš Herman, Karel Bláha, Jan Večeřa, Tomáš Lazarák, Vojtěch Novotný, Vladimíra Mužáková, Petr Vojtíšek
BACKGROUND: ST elevation myocardial infarction (STEMI) patients treated by primary percutaneous coronary intervention (PCI) are at higher risk of acute kidney injury (AKI) than patients undergoing PCI in stable clinical conditions. This fact suggests that mechanisms other than contrast nephrotoxicity are involved. AIM: To evaluate the incidence, risk factors, and consequences of AKI in patients undergoing primary PCI for STEMI in current daily practice. METHODS: Analysis of all consecutive patients who underwent primary PCI over a one-year period...
2016: Kardiologia Polska
Ismet Sarikaya
Routine use of cardiac positron emission tomography (PET) applications has been increasing but has not replaced cardiac single-photon emission computerized tomography (SPECT) studies yet. The majority of cardiac PET tracers, with the exception of fluorine-18 fluorodeoxyglucose (18F-FDG), are not widely available, as they require either an onsite cyclotron or a costly generator for their production. 18F-FDG PET imaging has high sensitivity for the detection of hibernating/viable myocardium and has replaced Tl-201 SPECT imaging in centers equipped with a PET/CT camera...
October 2015: Nuclear Medicine Communications
M Hrtánková, K Biringer, J Siváková, P Šumichrastová, P Lukáč, J Danko
OBJECTIVE: An overwiev of the new diagnostic method of fetal wellbeing - fetal magnetocardiography (fMCG). DESIGN: A review article. SETTING: Department of Gynecology and Obstetrics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Slovak Republic. METHODS: An analysis of the literature using database search engines PubMed, and SCOPE in field of fMCG. RESULTS: Fetal magnetocardiography is a non-invasive technique able to monitor the spontaneous electrophysiological activity of the fetal heart...
January 2015: Ceská Gynekologie
Osman Güvenç, Fatma Sevinç Şengül, Murat Saygı, Yakup Ergül, Alper Güzeltaş
Costello syndrome is a rare syndrome characterized by failure to thrive, short stature, mental motor retardation, characteristic facial features, macrocephaly, a short neck, loose soft skin with deep palmar and plantar creases, and hypertrichosis. Cardiac involvement is seen in almost two thirds of patients, and is a determinant for the prognosis of Costello syndrome. The most common cardiac anomalies are pulmonary stenosis, hypertrophic cardiomyopathy, atrial septal defect, ventricular septal defect and arrhytmia...
December 2014: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
Carlo Basile, Pasquale Libutti, Piero Lisi, Annalisa Teutonico, Luigi Vernaglione, Francesco Casucci, Carlo Lomonte
BACKGROUND: One of the most important pathogenetic factors involved in the onset of intradialysis arrhytmias is the alteration in electrolyte concentration, particularly potassium (K(+)). METHODS: Two studies were performed: Study A was designed to investigate above all the isolated effect of the factor time t on intradialysis K(+) mass balance (K(+)MB): 11 stable prevalent Caucasian anuric patients underwent one standard (∼4 h) and one long-hour (∼8 h) bicarbonate haemodialysis (HD) session...
March 2015: Nephrology, Dialysis, Transplantation
Husniye Baser, Nihal Akar Bayram, Burcak Polat, Berna Evranos, Reyhan Ersoy, Engin Bozkurt, Bekir Cakir
INTRODUCTION: It was aimed to calculate QT intervals in patients with acromegaly and to reveal its correlation between QT intervals, and growth hormone and insulin like growth factor-1. MATERIAL AND METHODS: Forty-one patients with acromegaly were enrolled into the study. Another 41 individuals with similar features, such as comorbid diseases, age and sex constituted the control group. The electrocardiographies of patients with acromegaly were evaluated at the baseline and after the follow-up...
July 2014: Acta Médica Portuguesa
Emir Karacaglar, Alp Aydinalp, Mehmet Coskun, Haldun Muderrisoglu
Anomalous origin of coronary arteries is also a relatively rare congenital malformation and has been reported as the cause of angina pectoris and arrhythmia. Long QT syndrome (LQTS) is a rare inherited arrythmogenic disease characterized by susceptibility to life-threatening arrhytmias andsudden cardiac death. We present a 36-year-old patient in whom two rare anomalies coexist and treated succesfully with β-blocker therapy.
September 28, 2011: Clinics and Practice
Walmor C De Mello
UNLABELLED: The influence of hypertonic solution on dye coupling was investigated in cell pairs isolated from the left ventricle of adult Sprague Dawley rats.The hypertonic solution together with Lucifer Yellow CH, were dialyzed into one cell of the pair using the whole cell clamp tecnique, and the diffusion of dye in the dialyzed as well as in non-dialyzed cell, was followed by measuring the intensity of fluorescence in both cells as a function of time.The results indicated that: (1) Lucifer Yellow CH dialyzed into one cell of the pair diffuses easily into the nondialyzed cell through gap junctions; (2) the intracellular dialysis of an hypertonic solution into one cell of the pair, increases the area of the dialyzed cell and reduced the area of the non-dialyzed cell suggesting intercellular movement of water; (3) the hypertonic solution dialyzed into one cell of the pair abolished the dye coupling; (4) the gap junction permeability (Pj) estimated before and after administration of hypertonic solution showed an appreciably decrease of Pj; (5) angiotensin (1-7) (Ang (1-7) (10-9M) administered to the bath re-established the dye coupling abolished by hypertonic solution and reduced the cell area; (6) the effect of Ang (1-7) was related to the activation of Mas receptor and was dependent on the activation of PKA...
May 1, 2014: Experimental Cell Research
Krzysztof Gałczyński, Beata Marciniak, Janusz Kudlicki, Zaneta Kimber-Trojnar, Bozena Leszczyńska-Gorzelak, Jan Oleszczukz
The incidence of cardiac arrhythmias is estimated et 1.2 per 1000 pregnancies, usually in the third trimester and 50% of them are asymptomatic. They may appear for the first time in pregnancy or have a recurring character An important risk factor related to their appearance is the presence of structural heart disease, which complicates < 1% of pregnancies. Generally the symptoms are mild and the treatment is not necessary but in some cases pharmacotherapy is necessary Pharmacotherapy must be a compromise between the potentially adverse effects of drugs on the fetus and the beneficial effects on the cardiovascular system of the mother...
October 2013: Ginekologia Polska
Martina Raudenska, Jaromir Gumulec, Petr Babula, Tibor Stracina, Marketa Sztalmachova, Hana Polanska, Vojtech Adam, Rene Kizek, Marie Novakova, Michal Masarik
Haloperidol (HP) is used for the symptomatic treatment of psychosis, manic phases, hyperactivity, aggressiveness, and acute delirium. Long-term use leads to various adverse side effects, especially to severe impairment of extrapyramidal nerve tracts and in particular, altered QT interval and increased incidence of arrhytmias. It is believed that cytotoxicity of HP and its metabolites is responsible for both neurotoxicity and cardiotoxicity. Extrapyramidal and cardiac adverse side effects may be explained by the HP-induced oxidative stress, as implicated by many studies...
December 2013: Mini Reviews in Medicinal Chemistry
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