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https://www.readbyqxmd.com/read/28922683/reproducibility-reliability-and-agreement-of-post-exercise-hypotension
#1
Rafael Yokoyama Fecchio, Marcel Chehuen, Leandro Campos Brito, Tiago Peçanha, Andréia Cristiane Carrenho Queiroz, Claudia Lucia de Moraes Forjaz
This study determined the reproducibility of post-exercise hypotension (PEH) calculated by the following methods: PEH_I=post-exercise BP - pre-exercise BP; PEH_II=post-exercise BP - post-control BP; and PEH_III=[(post-exercise BP - pre-exercise BP)-(post-control BP - pre-control BP)]. Twenty-five participants underwent four sessions divided in two blocks (test and retest). Each block consisted of one exercise and one control session. BP pressure was measured before and after the interventions. The presence of systematic error (paired t-tests), reliability [intraclass coefficient correlation (ICC)], and agreement [typical error (TE) and minimal detectable difference (MDD)] were evaluated...
September 18, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28922325/metacarpal-like-hand-classification-and-treatment-guidelines-for-microsurgical-reconstruction-with-toe-transplantation
#2
Fu-Chan Wei, Nidal F Al Deek, Yu-Te Lin, Chung-Chen Hsu, Cheng-Hung Lin
The metacarpal-like hand is a severe hand injury, never addressed before. It describes a hand that lost a significant degree of prehension through a wide array of amputations, involving all digits proximal to the functional length except in one finger or in two digits, including the thumb.Thumb condition can be used to differentiate between two types.In type I, the thumb is intact or amputated at/or distal to the interphalangeal joint (functional length); and therefore, the reconstruction is focused on fingers mainly...
September 14, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28921831/analysis-of-the-spotted-gar-genome-suggests-absence-of-causative-link-between-ancestral-genome-duplication-and-transposable-element-diversification-in-teleost-fish
#3
Domitille Chalopin, Jean-Nicolas Volff
Teleost fish have been shown to contain many superfamilies of transposable elements (TEs) that are absent from most tetrapod genomes. Since theories predict an increase in TE activity following polyploidization, such diversity might be linked to the 3R whole-genome duplication that occurred approximately 300 million years ago before the teleost radiation. To test this hypothesis, we have analyzed the genome of the spotted gar Lepisosteus oculatus, which diverged from the teleost lineage before the 3R duplication...
September 18, 2017: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/28919927/characterization-of-a-heat-tolerant-chlorella-sp-gd-mutant-with-enhanced-photosynthetic-co2-fixation-efficiency-and-its-implication-as-lactic-acid-fermentation-feedstock
#4
Tse-Min Lee, Yu-Fei Tseng, Chieh-Lun Cheng, Yi-Chuan Chen, Chih-Sheng Lin, Hsiang-Yen Su, Te-Jin Chow, Chun-Yen Chen, Jo-Shu Chang
BACKGROUND: Fermentative production of lactic acid from algae-based carbohydrates devoid of lignin has attracted great attention for its potential as a suitable alternative substrate compared to lignocellulosic biomass. RESULTS: A Chlorella sp. GD mutant with enhanced thermo-tolerance was obtained by mutagenesis using N-methyl-N'-nitro-N-nitrosoguanidine to overcome outdoor high-temperature inhibition and it was used as a feedstock for fermentative lactic acid production...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28918864/tuberculous-tracheoesophageal-fistula-a-rare-entity
#5
Ala-Eddin S Sagar, Sujith V Cherian, Rosa M Estrada-Y-Martin
No abstract text is available yet for this article.
September 14, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28917847/release-of-polyphenols-from-starch-chitosan-based-films-containing-thyme-extract
#6
Emma Talón, Kata T Trifkovic, María Vargas, Amparo Chiralt, Chelo González-Martínez
The release kinetics of thyme extract polyphenols (TE) from chitosan (CH), pea starch (S) and CH:S blend films in different solvents was evaluated, as well as their antioxidant activity in each release media. Pure starch films showed the fastest delivery rate and the highest delivery ratio of polyphenols, although the corresponding release media exhibited the lowest antioxidant capacity. TE provided CH based films with remarkable antioxidant activity, despite the lower polyphenol release obtained in all solvents, due to the strong polyphenols-chitosan interactions...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28916874/development-of-cacta-transposon-derived-scar-markers-and-their-use-in-population-structure-analysis-in-zea-mays
#7
Neha Samir Roy, Kyong-Cheul Park, Sung-Il Lee, Min-Ji Im, Rahul Vasudeo Ramekar, Nam-Soo Kim
Molecular marker technologies have proven to be an important breakthrough for genetic studies, construction of linkage maps and population genetics analysis. Transposable elements (TEs) constitute major fractions of repetitive sequences in plants and offer a wide range of possible areas to be explored as molecular markers. Sequence characterized amplified region (SCAR) marker development provides us with a simple and time saving alternative approach for marker development. We employed the CACTA-TD to develop SCARs and then integrated them into linkage map and used them for population structure and genetic diversity analysis of corn inbred population...
September 15, 2017: Genetica
https://www.readbyqxmd.com/read/28916214/management-of-acquired-nonmalignant-tracheoesophageal-fistula-surgical-pearls
#8
EDITORIAL
K Robert Shen
No abstract text is available yet for this article.
August 24, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28916047/anorectal-malformation-hirschsprung-s-disease-a-cross-sectional-comparison-of-quality-of-life-and-bowel-function-to-healthy-controls
#9
Shireen Anne Nah, Caroline C P Ong, Seyed Ehsan Saffari, Lin Yin Ong, Te-Lu Yap, Yee Low, Anette S Jacobsen
BACKGROUND: Patients with anorectal malformation (ARM) and Hirschsprung's disease (HD) face long-term disturbance in bowel function even after definitive surgery. This study evaluates the quality of life (QOL) of patients with ARM and HD, and compares them to healthy controls using self-report questionnaires. METHODOLOGY: A prospective study was performed recruiting patients with ARM or HD from September 2013 to December 2014 who had primary surgery done in our institution at least 2 years prior to participation...
August 25, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28914785/hsp90%C3%AE-mediates-bmi1-expression-in-breast-cancer-stem-progenitor-cells-through-facilitating-nuclear-translocation-of-c-myc-and-ezh2
#10
Yueh-Chun Lee, Wen-Wei Chang, Yi-Ying Chen, Yu-Hung Tsai, Ying-Hsiang Chou, Hsien-Chun Tseng, Hsin-Lin Chen, Chun-Chieh Wu, Ju Chang-Chien, Hsueh-Te Lee, Huei-Fan Yang, Bing-Yen Wang
Heat shock protein 90 (Hsp90) is a molecular chaperone that facilitates the correct folding and functionality of its client protein. Numerous Hsp90-client proteins are involved in cancer development. Thus, Hsp90 inhibitors have potential applications as anti-cancer drugs. We previously discovered that Hsp90α expression increased in breast cancer stem cells (BCSCs), which can initiate tumorigenesis and metastasis and resist treatment. In the present study, we further demonstrated that 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), an inhibitor of Hsp90, could suppress the self-renewal of BCSCs by downregulating B lymphoma Mo-MLV insertion region 1 homolog (BMI1), a polycomb family member with oncogenic activity in breast cancer...
September 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28914407/association-of-fetuin-b-with-markers-of-liver-fibrosis-in-nonalcoholic-fatty-liver-disease
#11
Thomas Ebert, Nicolas Linder, Alexander Schaudinn, Harald Busse, Joachim Berger, Ralf Lichtinghagen, Volker Keim, Johannes Wiegand, Thomas Karlas
OBJECTIVE: The liver-derived plasma protein fetuin B is associated with nonalcoholic fatty liver disease (NAFLD) and impaired glucose homeostasis in mice. However, its association with non-invasive ultrasound- and magnetic resonance (MR)-based markers of liver fibrosis and steatosis, the enhanced liver fibrosis (ELF) score, liver biopsy, as well as rs738409 in PNPLA3, has not been elucidated in NAFLD, so far. DESIGN AND METHODS: The association of circulating fetuin B and transient elastography (TE), controlled attenuation parameter (CAP), (1)H-MR-spectroscopy, the ELF score, liver biopsy, as well as risk alleles in rs738409 in PNPLA3, was studied in 101 NAFLD patients as compared to 15 healthy controls...
September 15, 2017: Endocrine
https://www.readbyqxmd.com/read/28914345/comparison-of-clinical-outcomes-between-open-and-thoracoscopic-repair-for-esophageal-atresia-with-tracheoesophageal-fistula-a-systematic-review-and-meta-analysis
#12
Yuhao Wu, Hongyu Kuang, Tiewei Lv, Chun Wu
OBJECTIVE: A meta-analysis was performed for a comparison of outcomes between open repair (OR) and thoracoscopic repair (TR) for esophageal atresia with tracheoesophageal fistula (EA with TEF). METHODS: Electronic databases, including PubMed, Cochrane Library, and Medline, were searched systematically for the literatures aimed mainly at comparing the therapeutic effects for EA with TEF administrated by OR and TR. Corresponding data sets were extracted and two reviewers independently assessed the methodological quality...
September 15, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28914302/li3co1-06-1-teo6-synthesis-single-crystal-structure-and-physical-properties-of-a-new-tellurate-compound-with-co-ii-co-iii-mixed-valence-and-orthogonally-oriented-li-ion-channels
#13
Gunter Heymann, Elisabeth Selb, Michaela Kogler, Thomas Götsch, Eva-Maria Köck, Simon Penner, Martina Tribus, Oliver Janka
A tellurate compound with Co(II)/Co(III) mixed valence states and lithium ions within orthogonally oriented channels was realized in Li3Co1.06(1)TeO6. The single-crystal structure determination revealed two independent and interpenetrating Li/O and (Co,Te)/O substructures with octahedral oxygen coordination of the metal atoms. In contrast to other mixed oxides, a honeycomb-like ordering of CoO6 and TeO6 octahedra was not observed. Li3Co1.06(1)TeO6 crystallizes orthorhombically with the following unit cell parameters and refinement results: Fddd, a = 588...
September 15, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28913328/editorial-oesophageal-atresia-tracheoesophageal-fistula
#14
EDITORIAL
Usha Krishnan, Christophe Faure
No abstract text is available yet for this article.
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28912075/ventricular-repolarization-disturbances-after-high-dose-intravenous-methylprednisolone-theraphy
#15
Gokhan Altunbas, Murat Sucu, Orhan Zengin
OBJECTIVE: There are no randomized trials evaluating the effects of pulse steroid treatment on cardiac electrophysiologic functions. The data are limited only to case series. In this study, we sought to evaluate the effects of high dose intravenous methylprednisolone therapy on indices of ventricular repolarization. METHODS: Fifty patients with various autoimmune and inflammatory disorders were enrolled to the study. Electrocardiography (ECG) was obtained 4h before and 12h after the pulse steroid treatment...
August 1, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28912014/acute-alerting-effects-of-light-a-systematic-literature-review
#16
REVIEW
Jan L Souman, Angelica M Tinga, Susan F Te Pas, Raymond van Ee, Björn N S Vlaskamp
Periodic, well timed exposure to light is important for our health and wellbeing. Light, in particular in the blue part of the spectrum, is thought to affect alertness both indirectly, by modifying circadian rhythms, and directly, giving rise to acute effects. We performed a systematic review of empirical studies on direct, acute effects of light on alertness to evaluate the reliability of these effects and to assess to what extent they depend on other factors, such as time of day, exposure duration and sleep pressure...
September 11, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28906471/largest-magnetic-moments-in-the-half-heusler-alloys-xcrz-x-li-k-rb-cs-z-s-se-te-a-first-principles-study
#17
Xiaotian Wang, Zhenxiang Cheng, Guodong Liu
A recent theoretical work indicates that intermetallic materials LiMnZ (Z = N, P) with a half-Heusler structure exhibit half-metallic (HM) behaviors at their strained lattice constants, and the magnetic moments of these alloys are expected to reach as high as 5 μB per formula unit. (Damewood et al. Phys. Rev. B2015, 91, 064409). This work inspired us to find new Heusler-based half-metals with the largest magnetic moment. With the help of the first-principles calculation, we reveal that XCrZ (X = K, Rb, Cs; Z = S, Se, Te) alloys show a robust, half-metallic nature with a large magnetic moment of 5 μB at their equilibrium and strained lattice constants in their most stable phases, while the excellent HM nature of LiCrZ (Z = S, Se, Te) alloys can be observed in one of their metastable phases...
September 14, 2017: Materials
https://www.readbyqxmd.com/read/28905887/an-efficient-non-viral-dendritic-vector-for-gene-delivery-in-tissue-engineering
#18
D P Walsh, A Heise, F J O'Brien, S-A Cryan
Recent developments within the field of tissue engineering (TE) have shown that biomaterial scaffold systems can be augmented via the incorporation of gene therapeutics. The objective of this study was to assess the potential of the activated polyamidoamine dendrimer (dPAMAM) transfection reagent (Superfect(TM)) as a gene delivery system to mesenchymal stem cells (MSCs) in both monolayer and 3D culture on collagen based scaffolds. dPAMAM-pDNA polyplexes at a mass ratio (M:R) 10:1 (dPAMAM : pDNA) (1 ug pDNA) were capable of facilitating prolonged reporter gene expression in monolayer MSCs which was superior to that facilitated using polyethylenimine (PEI)-pDNA polyplexes (2 ug pDNA)...
September 14, 2017: Gene Therapy
https://www.readbyqxmd.com/read/28905512/comparison-of-molecular-interactions-of-ag2-te-and-cdte-quantum-dots-with-human-serum-albumin-by-spectroscopic-approaches
#19
Qi Xiao, Yu Liang, Yi Liu, Shuangyan Lu, Shan Huang
Ag2 Te quantum dots (QDs) have attracted great attention in biological applications due to their superior photoluminescence qualities and good biocompatibility, but their potential biotoxicity at a molecular biology level has been rarely discussed. In order to better understand the basic behavior of Ag2 Te QDs in biological systems and compare their biotoxicity to cadmium-containing QDs, a series of spectroscopic measurements was applied to reveal the molecular interactions of Ag2 Te QDs and CdTe QDs with human serum albumin (HSA)...
September 14, 2017: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/28904110/the-chromatin-accessibility-signature-of-human-immune-aging-stems-from-cd8-t-cells
#20
Duygu Ucar, Eladio J Márquez, Cheng-Han Chung, Radu Marches, Robert J Rossi, Asli Uyar, Te-Chia Wu, Joshy George, Michael L Stitzel, A Karolina Palucka, George A Kuchel, Jacques Banchereau
Aging is linked to deficiencies in immune responses and increased systemic inflammation. To unravel the regulatory programs behind these changes, we applied systems immunology approaches and profiled chromatin accessibility and the transcriptome in PBMCs and purified monocytes, B cells, and T cells. Analysis of samples from 77 young and elderly donors revealed a novel and robust aging signature in PBMCs, with simultaneous systematic chromatin closing at promoters and enhancers associated with T cell signaling and a potentially stochastic chromatin opening mostly found at quiescent and repressed sites...
September 13, 2017: Journal of Experimental Medicine
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