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https://www.readbyqxmd.com/read/28743083/hall-effect-biosensors-with-ultraclean-graphene-film-for-improved-sensitivity-of-label-free-dna-detection
#1
Phan Thi Kim Loan, Dongqin Wu, Chen Ye, Xiaoqing Li, Vu Thanh Tra, Qiuping Wei, Li Fu, Aimin Yu, Lain-Jong Li, Cheng-Te Lin
The quality of graphene strongly affects the performance of graphene-based biosensors which are highly demanded for the sensitive and selective detection of biomolecules, such as DNA. This work reported a novel transfer process for preparing a residue-free graphene film using a thin gold supporting layer. A Hall effect device made of this gold-transferred graphene was demonstrated to significantly enhance the sensitivity (≈ 5 times) for hybridization detection, with a linear detection range of 1pM to 100nM for DNA target...
July 19, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28742942/regulation-of-transposable-elements-interplay-between-te-encoded-regulatory-sequences-and-host-specific-trans-acting-factors-in-drosophila-melanogaster
#2
Ana Marija Jakšić, Robert Kofler, Christian Schlötterer
Transposable elements (TEs) are mobile genetic elements that can move around the genome and their expression is one precondition for this mobility. Because the insertion of TEs in new genomic positions is largely deleterious, the molecular mechanisms for transcriptional suppression have been extensively studied. In contrast, very little is known about their primary transcriptional regulation. Here, we characterize the expression dynamics of TE families in Drosophila melanogaster across a broad temperature range (13-29°C)...
July 25, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28742326/tellurium-impregnated-porous-cobalt-doped-carbon-polyhedra-as-superior-cathode-for-lithium-tellurium-batteries
#3
Jiarui He, Weiqiang Lv, Yuanfu Chen, Kechun Wen, Chen Xu, Wanli Zhang, Yanrong Li, Wu Qin, Weidong He
Lithium-tellurium (Li-Te) batteries are attractive for energy storage owing to a high theoretical volumetric capacity of 2621 mAh cm-3. In this work, highly nanoporous cobalt and nitrogen co-doped carbon polyhedra (C-Co-N) derived from metal-organic framework (MOF) is synthesized and employed as tellurium host for Li-Te batteries. The Te@C-Co-N cathode with a high Te loading of 77.2 wt% exhibits record-breaking electrochemical performances including an ultrahigh initial capacity of 2615.2 mAh cm-3 approaching the theoretical capacity of Te (2621 mAh cm-3), a superior cycling stability with a high capacity retention of 93...
July 25, 2017: ACS Nano
https://www.readbyqxmd.com/read/28741893/when-epigenetics-meets-bioengineering-a-material-characteristics-and-surface-topography-perspective
#4
REVIEW
Lena Larsson, Sophia P Pilipchuk, William V Giannobile, Rogerio M Castilho
The field of tissue engineering and regenerative medicine (TE/RM) involves regeneration of tissues and organs using implantable biomaterials. The term epigenetics refers to changes in gene expression that are not encoded in the DNA sequence, leading to remodeling of the chromatin and activation or inactivation of gene expression. Recently, studies have demonstrated that these modifications are influenced not only by biological cues but also by mechanical and topographical signals. This review highlights the current knowledge on emerging approaches in TE/RM with a focus on the effect of materials and topography on the epigenetic expression pattern in cells with potential impacts on modulating regenerative biology...
July 25, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28740794/tissue-expanders-and-proton-beam-radiotherapy-what-you-need-to-know
#5
Ashley L Howarth, Joshua R Niska, Kenneth Brooks, Aman Anand, Martin Bues, Carlos E Vargas, Raman C Mahabir
Proton beam radiotherapy (PBR) has gained acceptance for the treatment of breast cancer because of unique beam characteristics that allow superior dose distributions with optimal dose to the target and limited collateral damage to adjacent normal tissue, especially to the heart and lungs. To determine the compatibility of breast tissue expanders (TEs) with PBR, we evaluated the structural and dosimetric properties of 2 ex vivo models: 1 model with internal struts and another model without an internal structure...
June 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28737936/a-ii-geteo6-a-mn-cd-pb-non-centrosymmetric-layered-tellurates-with-pbsb2o6-related-structure
#6
Sun Woo Kim, Zheng Deng, Shuang Yu, Haricharan Padmanabhan, Weiguo Zhang, Venkatraman Gopalan, Changqing Jin, Martha Greenblatt
A(II)GeTeO6 (A = Mn, Cd, Pb), new non-centrosymmetric (NCS) honeycomb-layered tellurates, were synthesized and characterized. A(II)GeTeO6 (A = Mn, Cd, Pb) crystallize in trigonal space group P312 (No. 149) of edge-sharing Ge(4+)O6 and Te(6+)O6 octahedra, which form honeycomb-like-layers in the ab-plane with A(II) (A = Mn, Cd, Pb) cations located between the layers. Their crystal structures are PbSb2O6-related, and the ordering of Ge(4+) and Te(6+) in octahedral environment breaks the inversion symmetry of the parent PbSb2O6 structure...
July 24, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28737809/hybrid-density-functional-theory-modeling-of-ca-zn-and-al-ion-batteries-using-the-chevrel-phase-mo6s8-cathode
#7
Taylor R Juran, Manuel Smeu
Hybrid density functional theory (DFT) is used to study the Chevrel phase Mo6X8 (X = S, Se, Te) as a promising cathode material intercalated with various metal ions (M = Li, Na, Be, Mg, Ca, Sr, Ba, Zn, Al). Electronic properties and voltages are calculated for each case. Ca ions are predicted to produce a voltage output ranging from 1.8-2.1 V, comparable to the voltage calculated for Li ions while providing two electrons per transferred ion. The highest voltage is determined to result when the chalcogen X in Mo6X8 is S, over Se or Te...
July 24, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28737233/direct-observation-of-inherent-atomic-scale-defect-disorders-responsible-for-high-performance-ti1-x-hfx-nisn1-y-sby-half-heusler-thermoelectric-alloys
#8
Ki Sung Kim, Young-Min Kim, Hyeona Mun, Jisoo Kim, Jucheol Park, Albina Y Borisevich, Kyu Hyoung Lee, Sung Wng Kim
Structural defects often dominate the electronic- and thermal-transport properties of thermoelectric (TE) materials and are thus a central ingredient for improving their performance. However, understanding the relationship between TE performance and the disordered atomic defects that are generally inherent in nanostructured alloys remains a challenge. Herein, the use of scanning transmission electron microscopy to visualize atomic defects directly is described and disordered atomic-scale defects are demonstrated to be responsible for the enhancement of TE performance in nanostructured Ti1-x Hfx NiSn1-y Sby half-Heusler alloys...
July 24, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28736926/effects-of-testosterone-enanthate-treatment-in-conjunction-with-resistance-training-on-thyroid-hormones-and-lipid-profile-in-male-wistar-rats
#9
M Zarei, M Zaeemi, A Rashidlamir
This study was conducted to determine the effects of 8-week administration of testosterone enanthate (TE) in conjunction with resistance training on thyroid hormones and lipid profiles. Sixty male adult Wistar rats were randomly divided into six groups: C: olive oil, RT: resistance training + olive oil, LD: TE (20 mg/kg), HD: TE (50 mg/kg), RT + LD: RT + TE (20 mg/kg), RT + HD: RT + TE (50 mg/kg). The RT consisted of climbing (5 reps/3 sets) a ladder carrying a load suspended from the tail. At the end, blood specimens were obtained from the orbital sinus and serum concentration of T4, T3, TSH and lipid profiles was determined...
July 23, 2017: Andrologia
https://www.readbyqxmd.com/read/28735662/68ga-dotatoc-and-18f-fdg-pet-ct-for-identifying-the-primary-lesions-of-suspected-and-metastatic-neuroendocrine-tumors-a%C3%A2-prospective-study-in-taiwan
#10
Shih-Hsin Chen, Yu-Chuan Chang, Tsann-Long Hwang, Jen-Shi Chen, Wen-Chi Chou, Chia-Hsun Hsieh, Ta-Sen Yeh, Jun-Te Hsu, Chun-Nan Yeh, Jeng-Hwei Tseng, Tse-Ching Chen, Tzu-Chen Yen
BACKGROUND/PURPOSE: To investigate the diagnostic accuracy of 68Ga-DOTATOC and 18F-FDG PET/CT to identify the primary foci in Taiwanese patients with clinically suspected neuroendocrine tumors (NET) and NET of unknown primary site. METHODS: Patients with clinically suspected NET and NET of unknown primary site were eligible. All participants underwent a conventional workup (including CT, MR, endoscopic ultrasound), 68Ga-DOTATOC, and 18F-FDG PET/CT. The results of pathology and findings on clinical follow-up served as the gold standard...
July 20, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28735660/case-detection-and-diagnosis-of-primary-aldosteronism-the-consensus-of-taiwan-society-of-aldosteronism
#11
Vin-Cent Wu, Ya-Hui Hu, Leay Kiaw Er, Ruoh-Fang Yen, Chia-Hui Chang, Ya-Li Chang, Ching-Chu Lu, Chin-Chen Chang, Jui-Hsiang Lin, Yen-Hung Lin, Tzung-Dau Wang, Chih-Yuan Wang, Shih Te Tu, Shih-Chieh Jeff Chueh, Ching-Chung Chang, Fen-Yu Tseng, Kwan-Dun Wu
BACKGROUND/PURPOSE: Even though the increasing clinical recognition of primary aldosteronism (PA) as a public health issue, its heightened risk profiles and the availability of targeted surgical/medical treatment being more understood, consensus in its diagnosis and management based on medical evidence, while recognizing the constraints of our real-world clinical practice in Taiwan, has not been reached. METHODS: The Taiwan Society of Aldosteronism (TSA) Task Force acknowledges the above-mentioned issues and reached this Taiwan PA consensus at its inaugural meeting, in order to provide updated information of internationally acceptable standards, and also to incorporate our local disease characteristics into the management of PA...
July 20, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28735064/associations-of-fibroblast-growth-factor-21-with-cardiovascular-risk-and-%C3%AE-cell-function-in-patients-who-had-no-history-of-diabetes
#12
Jun-Sing Wang, Wayne Huey-Herng Sheu, Wen-Jane Lee, I-Te Lee, Shih-Yi Lin, Wen-Lieng Lee, Kae-Woei Liang, Shing-Jong Lin
BACKGROUND: We investigated the associations of fibroblast growth factor 21 (FGF-21) with cardiovascular risk and β-cell function in patients who had no history of diabetes. METHODS: We enrolled 269 outpatients who had been referred for an oral glucose tolerance test (OGTT). Plasma glucose, insulin, and FGF-21 were measured before and at 2h after the OGTT. β-cell function was assessed using the insulinogenic index, corrected for insulin resistance. Patients' 10-year coronary heart disease (CHD) risk was assessed using the Chinese Multi-provincial Cohort Study functions...
July 19, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28733693/asia-s-first-minimal-access-left-ventricular-assist-device-implantation
#13
Jia Lin Soon, Teing Ee Tan, Choon Pin Lim, David Kl Sim, Hazel Sp Chan, Ka Lee Kerk, Cumaraswamy Sivathasan
No abstract text is available yet for this article.
June 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28733527/effects-of-chinese-herbal-medicines-on-the-occurrence-of-diabetic-retinopathy-in-type-2-diabetes-patients-and-protection-of-arpe-19-retina-cells-by-inhibiting-oxidative-stress
#14
Fuu-Jen Tsai, Te-Mao Li, Cheng-Hang Ko, Chi-Fung Cheng, Tsung-Jung Ho, Xiang Liu, Hsinyi Tsang, Ting-Hsu Lin, Chiu-Chu Liao, Ju-Pi Li, Shao-Mei Huang, Jung-Chun Lin, Chih-Chien Lin, Wen-Miin Liang, Ying-Ju Lin
Diabetic retinopathy is a microvascular complication of type 2 diabetes and the leading cause of acquired blindness. In Taiwan, Chinese herbal medicine (CHM) is a popular adjunctive therapy. In this study, we investigated the CHM prescription patterns and their effects. We identified 23,701 subjects with type 2 diabetes in a database, and after matching for age and gender, 6,948 patients each were assigned to CHM and non-CHM groups. In the female subgroups, the cumulative retinopathy probability was lower for the CHM users than that for the CHM non-users (P < 0...
June 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732940/sonochemical-synthesis-formation-mechanism-and-solar-cell-application-of-tellurium-nanoparticles
#15
Mehdi Mousavi-Kamazani, Reza Rahmatolahzadeh, Seyed Amin Shobeiri, Farshad Beshkar
Tellurium inherently tends to form 1-D structures and while the 0-D Te nanostructures have better properties and applications in solar cell. In the present study, 0-D Te nanostructures including rice-like and spherical nanoparticles with the particle size of 15-40nm were successfully synthesized via a facile sonochemical method. In the absence of ultrasonic irradiation nanorods were produced while performing the reaction under ultrasonic waves (at 200W for 30min) led to the formation of nanoparticles. Finally, the efficiency of various as-synthesized Te nanostructures in quantum dot-sensitized solar cells (QDSSCs) were evaluated...
November 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28732067/thromboembolic-adverse-event-study-of-combined-estrogen-progestin-preparations-using-japanese-adverse-drug-event-report-database
#16
Shiori Hasegawa, Toshinobu Matsui, Yuuki Hane, Junko Abe, Haruna Hatahira, Yumi Motooka, Sayaka Sasaoka, Akiho Fukuda, Misa Naganuma, Kouseki Hirade, Yukiko Takahashi, Yasutomi Kinosada, Mitsuhiro Nakamura
Combined estrogen-progestin preparations (CEPs) are associated with thromboembolic (TE) side effects. The aim of this study was to evaluate the incidence of TE using the Japanese Adverse Drug Event Report (JADER) database. Adverse events recorded from April 2004 to November 2014 in the JADER database were obtained from the Pharmaceuticals and Medical Devices Agency (PMDA) website (www.pmda.go.jp). We calculated the reporting odds ratios (RORs) of suspected CEPs, analyzed the time-to-onset profile, and assessed the hazard type using Weibull shape parameter (WSP)...
2017: PloS One
https://www.readbyqxmd.com/read/28731981/technology-in-strength-and-conditioning-assessing-bodyweight-squat-technique-with-wearable-sensors
#17
Martin A OʼReilly, Darragh F Whelan, Tomas E Ward, Eamonn Delahunt, Brian M Caulfield
O'Reilly, MA, Whelan, DF, Ward, TE, Delahunt, E, and Caulfield, BM. Technology in strength and conditioning: assessing bodyweight squat technique with wearable sensors. J Strength Cond Res 31(8): 2303-2312, 2017-Strength and conditioning (S&C) coaches offer expert guidance to help those they work with achieve their personal fitness goals. However, it is not always practical to operate under the direct supervision of an S&C coach and consequently individuals are often left training without expert oversight. Recent developments in inertial measurement units (IMUs) and mobile computing platforms have allowed for the possibility of unobtrusive motion tracking systems and the provision of real-time individualized feedback regarding exercise performance...
August 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28731760/steady-states-of-infinite-size-dissipative-quantum-chains-via-imaginary-time-evolution
#18
Adil A Gangat, Te I, Ying-Jer Kao
Directly in the thermodynamic limit, we show how to combine local imaginary and real-time evolution of tensor networks to efficiently and accurately find the nonequilibrium steady states (NESSs) of one-dimensional dissipative quantum lattices governed by a local Lindblad master equation. The imaginary time evolution first bypasses any highly correlated portions of the real-time evolution trajectory by directly converging to the weakly correlated subspace of the NESS, after which, real-time evolution completes the convergence to the NESS with high accuracy...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731683/synthesis-and-optical-properties-of-cu6e6-snph-2-pph2et-6-e-s-se-te-cluster-molecules
#19
Andreas Eichhöfer, Michael Kühn, Sergei Lebedkin, Max Kehry, Manfred M Kappes, Florian Weigend
A homologous series of three copper-tin-chalcogenide cluster molecules [Cu6E6(SnPh)2(PPh2Et)6] (E = S, Se, Te) was synthesized by reactions of CuO(O)CCH3 and PhSnCl3 with E(SiMe3)2 in the presence of PPh2Et. The cluster cage structures are similar, with slight differences in the bridging modes of the respective chalcogenide ligands E. The onset of the optical absorption displays a significant decrease of ca. 1.1 eV on going from sulfur to tellurium. The differences in bonding and electronic excitations can be rationalized by DFT and TDDFT calculations...
July 21, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28731570/susceptibility-weighted-imaging-and-quantitative-susceptibility-mapping-of-the-cerebral-vasculature-using-ferumoxytol
#20
Saifeng Liu, Jean-Christophe Brisset, Jiani Hu, E Mark Haacke, Yulin Ge
PURPOSE: To demonstrate the potential of imaging cerebral arteries and veins with ferumoxytol using susceptibility weighted imaging (SWI) and quantitative susceptibility mapping (QSM). MATERIALS AND METHODS: The relationships between ferumoxytol concentration and the apparent susceptibility at 1.5T, 3T, and 7T were determined using phantom data; the ability of visualizing subvoxel vessels was evaluated using simulations; and the feasibility of using ferumoxytol to enhance the visibility of small vessels was confirmed in three healthy volunteers at 7T(with doses 1 mg/kg to 4 mg/kg)...
July 21, 2017: Journal of Magnetic Resonance Imaging: JMRI
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