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https://www.readbyqxmd.com/read/28944455/introducing-a-new-column-peer-review-accreditation-and-a-focus-on%C3%A2-plasmalogens
#1
EDITORIAL
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No abstract text is available yet for this article.
September 2017: FEBS Letters
https://www.readbyqxmd.com/read/28944371/prosthetic-protocols-in-implant-based-oral-rehabilitations-a-systematic-review-on-the-clinical-outcome-of-monolithic-all-ceramic-single-and-multi-unit-prostheses
#2
Frank A Spitznagel, Sebastian D Horvath, Petra C Gierthmuehlen
AIM: The purpose of this systematic review was to assess the clinical performance of implant-supported monolithic all-ceramic single- and multi-unit restorations. MATERIALS AND METHODS: The electronic databases of MEDLINE via PubMed, the Cochrane Library (CENTRAL) and EMBASE were searched for clinical studies on monolithic all-ceramic single and multi-unit implant-supported fixed dental prostheses. Human studies with a mean follow-up of at least 2 years and published in English or German language peer-reviewed journals up until August 2016 were included...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28943990/motivators-and-barriers-of-tamoxifen-use-as-risk-reducing-medication-amongst-women-at-increased-breast-cancer-risk-a-systematic-literature-review
#3
REVIEW
B Meiser, W K T Wong, M Peate, C Julian-Reynier, J Kirk, G Mitchell
BACKGROUND: Selective estrogen receptor modulators, such as tamoxifen, reduce breast cancer risk by up to 50% in women at increased risk for breast cancer. Despite tamoxifen's well-established efficacy, many studies show that most women are not taking up tamoxifen. This systematic literature review aimed to identify the motivators and barriers to tamoxifen use 's amongst high-risk women. METHODS: Using MEDLINE, PsycINFO, and Embase plus reviewing reference lists of relevant articles published between 1995 and 2016, 31 studies (published in 35 articles) were identified, which addressed high-risk women's decisions about risk-reducing medication to prevent breast cancer and were peer-reviewed primary clinical studies...
2017: Hereditary Cancer in Clinical Practice
https://www.readbyqxmd.com/read/28943361/developing-a-short-form-of-the-german-barriers-questionnaire-ii-a-validation-study-in-four-steps
#4
Antje Koller, Patrick Jahn
CONTEXT: Patient-related barriers to cancer pain management are most commonly assessed with the Barriers Questionnaire-II (BQII; 27 items). OBJECTIVES: The aim of this study was to develop a valid short form of the BQII-German (BQII-G) to increase usability in clinical routines and reduce patient burden. METHODS: The validation study comprised a stepwise approach. In the first step, the linguistic validated version of the BQII-G was psychometrically tested for internal consistency and factor structure (N=207)...
September 21, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28942713/where-is-the-evidence-the-use-of-routinely-collected-patient-data-to-retain-adults-on-antiretroviral-treatment-in-low-and-middle-income-countries-a-state-of-the-evidence-review
#5
Nena do Nascimento, Catherine Barker, Isabel Brodsky
Retention rates in antiretroviral treatment (ART) in low- and middle-income countries are suboptimal for meeting global "90-90-90" treatment targets. Interventions using routinely collected patient data to follow up with ART defaulters is recommended to improve retention; yet, little is documented on how these data are used in practice. This state of the evidence review summarizes how facilities and programmes use patient data to retain adults on ART in low- and middle-income countries, and what effect, if any, these interventions have on retention...
September 25, 2017: AIDS Care
https://www.readbyqxmd.com/read/28941813/the-use-of-tailored-subheadings-was-successful-in-enhancing-compliance-with-consort-in-a-dental-journal
#6
Despina Koletsi, Padhraig S Fleming, Rolf G Behrents, Christopher D Lynchd, Nikolaos Pandis
OBJECTIVES: Efforts to enhance the reporting of clinical trials have intensified in recent years with automated strategies and editorial involvement showing promise in improving compliance with accepted guidelines. This study aimed to evaluate the effectiveness of a concerted approach to adherence to CONSORT (CONsolidated Standards Of Reporting Trials) guidelines in a dental journal. MATERIALS AND METHODS: Following the publication of an exemplar clinical trial on the American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO) website and related changes to the author guidelines, trial submissions were required to follow a standard format incorporating subheadings mirroring the CONSORT guidelines...
September 20, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28941605/prevention-of-left-ventricular-thrombus-formation-and-systemic-embolism-after-anterior-myocardial-infarction-a%C3%A2-systematic-literature-review
#7
REVIEW
Alexandra Bastiany, Marie-Eve Grenier, Alexis Matteau, Samer Mansour, Benoit Daneault, Brian J Potter
BACKGROUND: Anterior myocardial infarction (MI) with apical dysfunction is associated with an increased risk of left ventricular thrombus (LVT) formation and systemic embolism (SE). However, the role for prophylactic anticoagulation in current practice is a matter of debate. METHODS: We conducted a systematic review of peer-reviewed original articles in either English or French on the benefit of combining anticoagulation with standard therapy for the prevention of LVT/SE after MI by searching PubMed, Ovid/MedLine/Embase, the Cochrane Library, and Google Scholar...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28941564/cancer-therapy-with-checkpoint-inhibitors-establishing-a-role-for-ophthalmology
#8
REVIEW
Mary Elizabeth Davis, Jasmine H Francis
OBJECTIVE: To discuss interprofessional collaboration between the primary oncology clinicians and specialists in the management of immune-related ocular toxicities. DATA SOURCES: Peer-reviewed articles, case reports and systematic reviews. CONCLUSION: Accurate ophthalmologic assessment is critical for the prevention and treatment of ocular toxicities associated with immunotherapy. IMPLICATIONS FOR NURSING PRACTICE: Oncology nurses play a key role in early identification and management of ocular symptoms from immunotherapy; early referral to ophthalmic specialists can enhance recovery and preserve sight...
September 20, 2017: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/28940372/esophagus-segmentation-in-ct-via-3d-fully-convolutional-neural-network-and-random-walk
#9
Tobias Fechter, Sonja Adebahr, Dimos Baltas, Ismail Ben Ayed, Christian Desrosiers, Jose Dolz
PURPOSE: Precise delineation of organs at risk is a crucial task in radiotherapy treatment planning for delivering high doses to the tumour while sparing healthy tissues. In recent years, automated segmentation methods have shown an increasingly high performance for the delineation of various anatomical structures. However, this task remains challenging for organs like the esophagus, which have a versatile shape and poor contrast to neighboring tissues. For human experts, segmenting the esophagus from CT images is a time-consuming and error-prone process...
September 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28939978/society-of-skeletal-radiology-2017-annual-meeting-summary
#10
REVIEW
Michael G Fox, Laura W Bancroft
Peer-reviewed abstracts presented at the 2017 Society of Skeletal Radiology (SSR) Annual Meeting were reviewed following oral presentation. Topics felt to be of potential interest to musculoskeletal (MSK) investigators and practicing clinicians are highlighted in this compilation and analysis of the meeting. New concepts regarding MSK imaging and intervention, MSK protocols and techniques and quality improvement are included. ePoster highlights are also presented.
September 22, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28939582/a-randomised-controlled-trial-of-an-intervention-delivered-by-app-instant-messaging-to-increase-the-acceptability-of-effective-contraception-among-young-people-in-tajikistan-study-protocol
#11
Ona McCarthy, Baptiste Leurent, Phil Edwards, Ravshan Tokhirov, Caroline Free
INTRODUCTION: Women in lower income countries experience unintended pregnancies at a higher rate compared with women in higher income countries. Unintended pregnancy is associated with numerous poorer health outcomes for both women and their children. In Tajikistan, an estimated 26% of married individuals aged 15-24 years have an unmet need for contraception. The strong cultural value placed on childbearing and oppositional attitudes towards contraception are major barriers to contraceptive uptake in the country...
September 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28939581/protocol-of-a-randomised-controlled-trial-characterising-the-immune-responses-induced-by-varicella-zoster-virus-vzv-vaccination-in-healthy-kenyan-women-setting-the-stage-for-a-potential-vzv-based-hiv-vaccine
#12
Catia T Perciani, Walter Jaoko, Sharon Walmsley, Bashir Farah, Salaheddin M Mahmud, Mario Ostrowski, Omu Anzala, Kavi-Icr Team, Kelly S MacDonald
INTRODUCTION: A protective HIV vaccine would be expected to induce durable effector immune responses at the mucosa, restricting HIV infection at its portal of entry. We hypothesise that use of varicella-zoster virus (VZV) as an HIV delivery vector could generate sustained and robust tissue-based immunity against HIV antigens to provide long-term protection against HIV. Given that HIV uniquely targets immune-activated T cells, the development of human vaccines against HIV must also involve a specific examination of the safety of the vector...
September 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28939574/publication-of-interventional-phase-3-and-4-clinical-trials-in-radiation-oncology-an-observational-study
#13
Jaime Pérez-Alija, Pedro Gallego, Isabel Linares, Eva Ambroa, Agustí Pedro
OBJECTIVES: Clinical trials produce the best data available for decision-making in modern evidence-based medicine. We aimed to determine the rate of non-publication of interventional phase 3 and 4 clinical trials involving patients with cancer undergoing radiotherapy. SETTING: The ClinicalTrials.gov database was searched for interventional phase 3 and 4 trials in radiotherapy with a primary completion date before 1 January 2013. We determined how many of these registry entries have not published the compulsory deposition of their results in the database and performed a systematic search for published studies in peer-reviewed journals...
September 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28939568/protocol-for-a-realist-review-of-complex-interventions-to-prevent-adolescents-from-engaging-in-multiple-risk-behaviours
#14
Christina Cooper, Monique Lhussier, Janet Shucksmith, Susan Mary Carr
OBJECTIVES: Adolescent risk behaviours are a key health concern. The purpose of this research is to gaina deeper understanding of how, why, for whom, and inwhat circumstances complex adolescent risk behaviourprevention programmes are most successful. METHODS AND ANALYSIS: To understand how adolescent risk behaviour prevention programmes work in a reallife context, a realist synthesis will be undertaken, operationalised in four phases. Phase one Developing a framework to map the theoretical and conceptual landscape of adolescent risk behaviour prevention...
September 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28939565/long-term-risk-of-recurrence-after-discontinuing-anticoagulants-for-a-first-unprovoked-venous-thromboembolism-protocol-for-a-systematic-review-and-meta-analysis
#15
Faizan Khan, Alvi Rahman, Marc Carrier, Clive Kearon, Sam Schulman, Francis Couturaud, Paolo Prandoni, Sabine Eichinger, Cecilia Becattini, Giancarlo Agnelli, Harry R Büller, Timothy A Brighton, Gualtiero Palareti, Laurent Pinede, Elham Sabri, Brian Hutton, George A Wells, Marc A Rodger
INTRODUCTION: For patients with a first unprovoked venous thromboembolism (VTE), the optimal duration of anticoagulation is a crucial clinical dilemma which has yet to be resolved. The decision to stop anticoagulant therapy (AT) after the initial 3-6 months or to continue AT indefinitely, is primarily governed by the long-term risk of recurrence when treatment is discontinued. This risk however, is not well established, hindering decision making. METHODS AND ANALYSIS: We will conduct a systematic review and a meta-analysis of studies involving patients diagnosed with a first, symptomatic unprovoked VTE or VTE provoked by minor transient risk factors, who have completed at least 3 months of initial AT; and who were followed-up for standardised time intervals of 1, 2, 5, 10 and 20 years (±3 months) after stopping AT...
September 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28939228/reputation-management-and-content-control-an-analysis-of-radiation-oncologists-digital-identities
#16
Arpan V Prabhu, Christopher Kim, Eison De Guzman, Eric Zhao, Evan Madill, Jonathan Cohen, David R Hansberry, Nitin Agarwal, Dwight E Heron, Sushil Beriwal
INTRODUCTION: Google is the most popular search engine in the United States, and patients are increasingly relying on online webpages to seek information about individual physicians. This study aims to characterize what patients find when they search for radiation oncologists online. METHODS AND MATERIALS: The Centers for Medicare and Medicaid Services (CMS) Physician Comparable Downloadable File was used to identify all Medicare-participating radiation oncologists in the United States and Puerto Rico...
August 19, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28938872/effect-of-vitamin-a-supplementation-on-gut-microbiota-in-children-with-autism-spectrum-disorders-a-pilot-study
#17
Juan Liu, Xiao Liu, Xue-Qin Xiong, Ting Yang, Ting Cui, Na-Li Hou, Xi Lai, Shu Liu, Min Guo, Xiao-Hua Liang, Qian Cheng, Jie Chen, Ting-Yu Li
BACKGROUND: Dysbiosis of gut microbiota are commonly reported in autism spectrum disorder (ASD) and may contribute to behavioral impairment. Vitamin A (VA) plays a role in regulation of gut microbiota. This study was performed to investigate the role of VA in the changes of gut microbiota and changes of autism functions in children with ASD. RESULTS: Sixty four, aged 1 to 8 years old children with ASD completed a 6-month follow-up study with VA intervention. High-performance liquid chromatography was used to assess plasma retinol levels...
September 22, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28937874/can-a-label-help-me-drink-in-moderation-a-review-of-the-evidence-on-standard-drink-labelling
#18
Ashley Wettlaufer
INTRODUCTION: Understanding the concept of a standard drink (SD) is foundational knowledge to many public health policies aimed at reducing alcohol-related harms. These policies include adhering to low-risk drinking guidelines, screening brief intervention and referral activities, and counter alcohol-impaired driving initiatives. A lack of awareness of SDs might preclude the effectiveness of these interventions. A systematic review was conducted to review the evidence about how effective alcohol labels are in communicating SD information to the consumer...
September 22, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28937870/student-led-screening-of-school-children-for-refractive-error-correction
#19
Dipesh Bhattarai, Subodh Gnyawali, Arpan Silwal, Sudan Puri, Anita Shrestha, Man Bahadur Kunwar, Madan Prasad Upadhyay
PURPOSE: Detection and correction of uncorrected refractive errors among 12 million children is an overwhelming task for the 500 currently available eye-care professionals in Nepal. A mid-term review of VISION 2020 goals in Nepal has recommended utilizing alternative human resources that could screen children for visual impairment. This study was conducted to assess the validity of vision screening of school children by trained high school students when compared to optometrist testing as the gold standard...
September 22, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28937790/the-doctor-of-philosophy-experience-of-athletic-trainers-facilitators-and-barriers-to-anticipatory-faculty-socialization
#20
Thomas Bowman, Joanne Klossner, Stephanie Mazerolle
CONTEXT:   It is important to understand the process whereby athletic trainers learn about their future roles, particularly when the roles can be complex and demanding. Little is known about the experiences of athletic training doctoral students, including facilitators and barriers to socialization as aspiring faculty members. OBJECTIVE:   To investigate factors influencing the anticipatory socialization of athletic training doctoral students into future faculty roles...
September 22, 2017: Journal of Athletic Training
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