keyword
MENU ▼
Read by QxMD icon Read
search

duarte

keyword
https://www.readbyqxmd.com/read/28922611/the-effects-of-cryopreservation-on-different-passages-of-fibroblast-cell-culture-in-brown-brocket-deer-mazama-gouazoubira
#1
Lívia C Magalhães, Maajid H Bhat, Jeferson L S Freitas, Luciana M Melo, Dárcio I A Teixeira, Luiz C A Pinto, Lília M C Câmara, José M B Duarte, Vicente J F Freitas
The brown brocket deer Mazama gouazoubira is 1 of the 10 recognized brocket deer of the Neotropical region. Recently, this species has suffered a population decline due to current threats, mainly poaching and habitat loss. Several studies have shown that some endangered species can benefit from interspecies somatic cell nuclear transfer technology through the use of their somatic cells, such as the fibroblasts. Thus, the aim of this study was to verify the viability and the effect of cryopreservation on fibroblasts after several passages...
September 18, 2017: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/28920068/tetrabenazine-versus-deutetrabenazine-for-huntington-s-disease-twins-or-distant-cousins
#2
Filipe B Rodrigues, Gonçalo S Duarte, João Costa, Joaquim J Ferreira, Edward J Wild
BACKGROUND: Tetrabenazine is the only US Food and Drug Administration-approved drug for Huntington's disease, and deutetrabenazine was recently tested against placebo. A switching-trial from tetrabenazine to deutetrabenazine is underway, but no head-to-head, blinded, randomized controlled trial is planned. Using meta-analytical methodology, the authors compared these molecules. METHODS: RCTs comparing tetrabenazine or deutetrabenazine with placebo in Huntington's disease were searched...
July 2017: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/28919736/carbon-nanotubes-gathered-onto-silica-particles-lose-their-biomimetic-properties-with-the-cytoskeleton-becoming-biocompatible
#3
Elena González-Domínguez, Nerea Iturrioz-Rodríguez, Esperanza Padín-González, Juan Villegas, Lorena García-Hevia, Moisés Pérez-Lorenzo, Wolfgang J Parak, Miguel A Correa-Duarte, Mónica L Fanarraga
Carbon nanotubes (CNTs) are likely to transform the therapeutic and diagnostic fields in biomedicine during the coming years. However, the fragmented vision of their side effects and toxicity in humans has proscribed their use as nanomedicines. Most studies agree that biocompatibility depends on the state of aggregation/dispersion of CNTs under physiological conditions, but conclusions are confusing so far. This study designs an experimental setup to investigate the cytotoxic effect of individualized multiwalled CNTs compared to that of identical nanotubes assembled on submicrometric structures...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28919506/the-role-of-climatic-cycles-and-trans-saharan-migration-corridors-in-species-diversification-biogeography-of-psammophis-schokari-group-in-north-africa
#4
Duarte Vasconcelos Gonçalves, Fernando Martínez-Freiría, Pierre-André Crochet, Philippe Geniez, Salvador Carranza, José Carlos Brito
Highlands, hydrographic systems and coastal areas have been hypothesised to form corridors across the hyperarid Sahara desert in North Africa, allowing dispersal and gene flow for non-xeric species. Here we aim to provide a genetic test for the trans-Saharan corridor model, and predict the location and stability of ecological-corridors, by combining phylogeography and palaeoclimatic modelling. The model was the Psammophis schokari (Schokari sand racer) group, fast-moving and widely distributed generalist colubrids occurring mostly in arid and semiarid scrublands...
September 14, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28918464/what-s-next-in-complex-networks-capturing-the-concept-of-attacking-play-in-invasive-team-sports
#5
REVIEW
João Ramos, Rui J Lopes, Duarte Araújo
The evolution of performance analysis within sports sciences is tied to technology development and practitioner demands. However, how individual and collective patterns self-organize and interact in invasive team sports remains elusive. Social network analysis has been recently proposed to resolve some aspects of this problem, and has proven successful in capturing collective features resulting from the interactions between team members as well as a powerful communication tool. Despite these advances, some fundamental team sports concepts such as an attacking play have not been properly captured by the more common applications of social network analysis to team sports performance...
September 16, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28917459/yellow-facial-papules-associated-with-frontal-fibrosing-alopecia-a-distinct-histologic-pattern-and-response-to-isotretinoin
#6
Ana Filipa Pedrosa, Ana Filipa Duarte, Eckart Haneke, Osvaldo Correia
No abstract text is available yet for this article.
October 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28917269/triplet-folfoxiri-versus-doublet-folfox-or-folfiri-backbone-chemotherapy-as-first-line-treatment-of-metastatic-colorectal-cancer-a-systematic-review-and-meta-analysis
#7
REVIEW
Rui Pedro Marques, Gonçalo S Duarte, Carmelo Sterrantino, Helena Luna Pais, António Quintela, Ana Paula Martins, João Costa
Uncertainty exists regarding the comparative effectiveness of triplet chemotherapy (FOLFOXIRI) as backbone first-line chemotherapy for metastatic colorectal cancer (mCRC). We conducted a systematic review and meta-analysis of randomized-controlled trials (RCTs) comparing triplet versus doublet chemotherapy (FOLFOX or FOLFIRI) as first-line therapy in mCRC. Methods and reporting followed PRISMA and SAMPL guidelines. Eight RCTs were included, comprising 1732 patients. In pooled analysis, FOLFOXIRI was associated with improvements in efficacy outcomes, notably with a 25% survival increase (95%CI: 10-37%)...
October 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28917219/reuma-pt-contribution-to-the-knowledge-of-immune-mediated-systemic-rheumatic-diseases
#8
Maria José Santos, Helena Canhão, Ana Filipa Mourão, Filipa Oliveira Ramos, Cristina Ponte, Cátia Duarte, Anabela Barcelos, Fernando Martins, José António Melo Gomes
Patient registries are key instruments aimed at a better understanding of the natural history of diseases, at assessing the effectiveness of therapeutic interventions, as well as identifying rare events or outcomes that are not captured in clinical trials. However, the potential of registries goes far beyond these aspects. For example, registries promote the standardization of clinical practice, can also provide information on domains that are not routinely collected in clinical practice and can support decision-making...
September 14, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28914489/responses-of-microbial-decomposers-to-drought-in-streams-may-depend-on-the-environmental-context
#9
Sofia Duarte, Juanita Mora-Gómez, Anna M Romaní, Fernanda Cássio, Cláudia Pascoal
A consequence of drought in streams is the emersion of decomposing leaf litter, which may alter organic matter recycling. We assessed the effects of emersion on decomposition of black poplar leaves and associated microbes (microbial biomass, extracellular enzyme activities and microbial diversity) in two streams with distinct characteristics, in particular nutrients, temperature and oxygen levels. Leaf decomposition rates, fungal biomass and extracellular enzyme activities were lower in the most impacted stream (high nutrients and temperature, low oxygen)...
September 15, 2017: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/28913828/diet-and-body-shape-changes-of-p%C3%A4-roko-kelloggella-disalvoi-gobiidae-from-intertidal-pools-of-easter-island
#10
J Vera-Duarte, C A Bustos, M F Landaeta
This study assesses seasonal variation in the morphology and diet of juveniles and adults of the Easter Island endemic goby Kelloggella disalvoi from intertidal pools during September-October 2015 (spring) and June-July 2016 (winter), utilizing geometric morphometric and gut-content analyses. A set of 16 landmarks was digitized in 128 individuals. Shape changes related to size changes (i.e. allometry) were low (18·6%) and were seasonally similar. Body shape changes were mainly dorsoventral (44·2% of variance) and comprised posteroventral displacement of the premaxilla and bending of the body...
September 15, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28913603/influence-of-anthropometry-tmd-and-sex-on-molar-bite-force-in-adolescents-with-and-without-orthodontic-needs
#11
Barbara de Lima Lucas, Taís de Souza Barbosa, Paula Midori Castelo, Maria Beatriz Duarte Gavião
PURPOSE: Bite force has been studied as representative of functional indices of mastication and its value may have diagnostic significance in disorders of the musculoskeletal system of facial bones. This study aimed to evaluate bite force in adolescents with and without orthodontic needs considering presence of temporomandibular disorders (TMD) as well as anthropometry: craniofacial dimensions and body mass index (BMI). METHODS: A total of 80 subjects were screened (61 females, 19 males; 18 ± 3 years old)...
September 14, 2017: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/28913418/unveiling-the-role-and-life-strategies-of-viruses-from-the-surface-to-the-dark-ocean
#12
Elena Lara, Dolors Vaqué, Elisabet Laia Sà, Julia A Boras, Ana Gomes, Encarna Borrull, Cristina Díez-Vives, Eva Teira, Massimo C Pernice, Francisca C Garcia, Irene Forn, Yaiza M Castillo, Aida Peiró, Guillem Salazar, Xosé Anxelu G Morán, Ramon Massana, Teresa S Catalá, Gian Marco Luna, Susana Agustí, Marta Estrada, Josep M Gasol, Carlos M Duarte
Viruses are a key component of marine ecosystems, but the assessment of their global role in regulating microbial communities and the flux of carbon is precluded by a paucity of data, particularly in the deep ocean. We assessed patterns in viral abundance and production and the role of viral lysis as a driver of prokaryote mortality, from surface to bathypelagic layers, across the tropical and subtropical oceans. Viral abundance showed significant differences between oceans in the epipelagic and mesopelagic, but not in the bathypelagic, and decreased with depth, with an average power-law scaling exponent of -1...
September 2017: Science Advances
https://www.readbyqxmd.com/read/28912466/using-a-novel-microfabricated-model-of-the-alveolar-capillary-barrier-to-investigate-the-effect-of-matrix-structure-on-atelectrauma
#13
N Higuita-Castro, M T Nelson, V Shukla, P A Agudelo-Garcia, W Zhang, S M Duarte-Sanmiguel, J A Englert, J J Lannutti, D J Hansford, S N Ghadiali
The alveolar-capillary barrier is composed of epithelial and endothelial cells interacting across a fibrous extracelluar matrix (ECM). Although remodeling of the ECM occurs during several lung disorders, it is not known how fiber structure and mechanics influences cell injury during cyclic airway reopening as occurs during mechanical ventilation (atelectrauma). We have developed a novel in vitro platform that mimics the micro/nano-scale architecture of the alveolar microenvironment and have used this system to investigate how ECM microstructural properties influence epithelial cell injury during airway reopening...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28910984/genomic-and-transcriptomic-analysis-of-saccharomyces-cerevisiae-isolates-with-focus-in-succinic-acid-production
#14
Ricardo Franco-Duarte, Daniela Bessa, Filipa Gonçalves, Rosa Martins, António César Silva-Ferreira, Dorit Schuller, Paula Sampaio, Célia Pais
Succinic acid is a platform chemical that plays an important role as precursor for the synthesis of many valuable bio-based chemicals. Its microbial production from renewable resources has seen great developments, specially exploring the use of yeasts to overcome the limitations of using bacteria. The objective of the present work was to screen for succinate-producing isolates, using a yeast collection with different origins and characteristics. Four strains were chosen, two as promising succinic acid producers, in comparison with two low producers...
September 1, 2017: FEMS Yeast Research
https://www.readbyqxmd.com/read/28910720/study-of-the-influence-of-physical-chemical-and-biological-conditions-that-influence-the-deterioration-and-protection-of-underwater-cultural-heritage
#15
Manuel Bethencourt, Tomás Fernández-Montblanc, Alfredo Izquierdo, Manuel María González-Duarte, Cristian Muñoz-Mas
Two wrecks related to the Battle of Trafalgar (1805) were studied. Following the guidelines of the UNESCO-2001 Convention for the Protection of the Underwater Cultural Heritage, a holistic and interdisciplinary approach based on the development of four of the thirty-six Rules of this international agreement was applied. A non-destructive survey technique was developed to obtain information from the scattered cannons and anchors without altering their condition (Rule 4). The work performed provided information about the origin of both wrecks, the Fougueux and the Bucentaure, two ships of the line of the French Navy, and allowed to characterize the state of conservation at each site without jeopardizing their future conservation in the marine environment...
September 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28910431/hla-mismatched-microtransplant-in-older-patients-newly-diagnosed-with-acute-myeloid-leukemia-results-from-the-microtransplantation-interest-group
#16
Mei Guo, Nelson J Chao, Jian-Yong Li, David A Rizzieri, Qi-Yun Sun, Ann Mohrbacher, Elizabeth F Krakow, Wan-Jun Sun, Xu-Liang Shen, Xin-Rong Zhan, De-Pei Wu, Li Liu, Juan Wang, Min Zhou, Lin-Hua Yang, Yang-Yi Bao, Zheng Dong, Bo Cai, Kai-Xun Hu, Chang-Lin Yu, Jian-Hui Qiao, Hong-Li Zuo, Ya-Jing Huang, Anthony D Sung, Jun-Xiao Qiao, Zhi-Qing Liu, Tie-Qiang Liu, Bo Yao, Hong-Xia Zhao, Si-Xuan Qian, Wei-Wei Liu, Rafael Forés, Rafael F Duarte, Hui-Sheng Ai
Importance: The outcome of older patients with acute myeloid leukemia (AML) remains unsatisfactory. Recent studies have shown that HLA-mismatched microtransplant could improve outcomes in such patients. Objective: To evaluate outcomes in different age groups among older patients with newly diagnosed AML who receive HLA-mismatched microtransplant. Design, Setting, and Participants: This multicenter clinical study included 185 patients with de novo AML at 12 centers in China, the United States, and Spain in the Microtransplantation Interest Group...
September 14, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28910310/gugulipid-causes-hypercholesterolemia-leading-to-endothelial-dysfunction-increased-atherosclerosis-and-premature-death-by-ischemic-heart-disease-in-male-mice
#17
Andrea Leiva, Susana Contreras-Duarte, Ludwig Amigo, Esteban Sepúlveda, Mauricio Boric, Verónica Quiñones, Dolores Busso, Attilio Rigotti
For proper cholesterol metabolism, normal expression and function of scavenger receptor class B type I (SR-BI), a high-density lipoprotein (HDL) receptor, is required. Among the factors that regulate overall cholesterol homeostasis and HDL metabolism, the nuclear farnesoid X receptor plays an important role. Guggulsterone, a bioactive compound present in the natural product gugulipid, is an antagonist of this receptor. This natural product is widely used globally as a natural lipid-lowering agent, although its anti-atherogenic cardiovascular benefit in animal models or humans is unknown...
2017: PloS One
https://www.readbyqxmd.com/read/28905627/an-aminocatalyzed-michael-addition-iron-mediated-decarboxylative-cyclization-sequence-for-the-preparation-of-2-3-4-6-tetrasubstituted-pyridines-scope-and-mechanistic-insights
#18
Mateus L Stivanin, Marcelo Duarte, Camila Sartori, Naylil M R Capreti, Celio F F Angolini, Igor D Jurberg
A novel, scalable strategy for the preparation of 2,3,4,6-tetrasubstituted pyridines is described. This protocol has two steps: an aminocatalyzed addition of ketones to alkylidene isoxazol-5-ones, followed by an iron-mediated decarboxylative cyclization event. Mechanistic insights for both steps are provided based on HRMS-ESI(+) studies.
September 14, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28903728/increased-survival-and-proliferation-of-the-epidemic-strain-mycobacterium-abscessus-subsp-massiliense-crm0019-in-alveolar-epithelial-cells
#19
Giovanni Monteiro Ribeiro, Cristianne Kayoko Matsumoto, Fernando Real, Daniela Teixeira, Rafael Silva Duarte, Renato Arruda Mortara, Sylvia Cardoso Leão, Cristiane de Souza Carvalho-Wodarz
BACKGROUND: Outbreaks of infections caused by rapidly growing mycobacteria have been reported worldwide generally associated with medical procedures. Mycobacterium abscessus subsp. massiliense CRM0019 was obtained during an epidemic of postsurgical infections and was characterized by increased persistence in vivo. To better understand the successful survival strategies of this microorganism, we evaluated its infectivity and proliferation in macrophages (RAW and BMDM) and alveolar epithelial cells (A549)...
September 13, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28902456/safety-and-efficacy-of-hydroxyapatite-scaffold-in-the-prevention-of-jaw-osteonecrosis-in-vivo
#20
Adriana Duarte de Almeida, Fernanda Gomes Leite, Marco Vinícius Chaud, Márcia de Araújo Rebelo, Liliane Cristine Ferreira de Souza Borges, Fabia Judice Marques Viroel, Alessandre Hataka, Denise Grotto
Two scaffolds of chitosan/sodium alginate/hydroxyapatite (Ch/NaAlg/Hap) 1:1:0.2 and 1:1:0.6 were evaluated in the prevention of bisphosphonate-induced jaw osteonecrosis. Two groups of rats (n = 24, according to the euthanasia time: 15 or 30 days after the last Zoledronic acid (ZA) administration) were subdivided in four subgroups (n = 6): I - Control (saline + teeth extraction); II - ZA 0.6 mg/kg + teeth extraction; III - ZA + teeth extraction + scaffold 1:1:0.2; IV - ZA + teeth extraction + scaffold 1:1:0...
September 13, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
keyword
keyword
108712
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"