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https://www.readbyqxmd.com/read/28213779/adenoid-bacterial-colonization-in-a-paediatric-population
#1
João Subtil, João Carlos Rodrigues, Lúcia Reis, Luís Freitas, Joana Filipe, Alberto Santos, Carlos Macor, Aida Duarte, Luisa Jordao
Adenoids play a key role in both respiratory and ear infection in children. It has also been shown that adenoidectomy improves these symptoms in this population. The main goal of the present study was to evaluate adenoid bacterial colonization and document a possible relation with infectious respiratory disease. A prospective observational study was designed to evaluate the proposed hypothesis in a paediatric population submitted to adenoidectomy by either infectious or non-infectious indications and compare these two cohorts...
February 18, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28212611/impact-of-novel-snps-identified-in-cynara-cardunculus-genes-on-functionality-of-proteins-regulating-phenylpropanoid-pathway-and-their-association-with-biological-activities
#2
Ana Margarida Ferro, Patrícia Ramos, Olinda Guerreiro, Eliana Jerónimo, Inês Pires, Carmen Capel, Juan Capel, Rafael Lozano, Maria F Duarte, M Margarida Oliveira, Sónia Gonçalves
BACKGROUND: Cynara cardunculus L. offers a natural source of phenolic compounds with the predominant molecule being chlorogenic acid. Chlorogenic acid is gaining interest due to its involvement in various biological properties such as, antibacterial, antifungal, antioxidant, hepatoprotective, and anticarcinogenic activities. RESULTS: In this work we screened a Cynara cardunculus collection for new allelic variants in key genes involved in the chlorogenic acid biosynthesis pathway...
February 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28212512/are-antifouling-paint-particles-a-continuous-source-of-toxic-chemicals-to-the-marine-environment
#3
Sanye Soroldoni, Fiamma Abreu, Ítalo Braga Castro, Fabio Andrei Duarte, Grasiela Lopes Leães Pinho
Antifouling paint particles (APPs) are generated during periodical maintenance of boat hulls. Chemical composition and toxicity (either chronic or acute) of APPs found in the sediment was evaluated using the epibenthic copepod Nitokra sp. The APPs analyzed showed the presence of high levels of metals such as Cu (234,247±268μgg(-1)), Zn (112,404±845μgg(-1)) and the booster biocide DCOIT (0.13μgg(-1)). Even at low concentrations (as from 5mgg(-1) of APPs by mass of sediment) a significantly decrease in the fecundity was observed in laboratory tests...
February 3, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28210565/label-free-proteome-analysis-of-plasma-from-patients-with-breast-cancer-stage-specific-protein-expression
#4
Marina Duarte Pinto Lobo, Frederico Bruno Mendes Batista Moreno, Gustavo Henrique Martins Ferreira Souza, Sara Maria Moreira Lima Verde, Renato de Azevedo Moreira, Ana Cristina de Oliveira Monteiro-Moreira
Breast cancer is one of the most commonly diagnosed types of cancer among women. Breast cancer mortality rates remain high probably because its diagnosis is hampered by inaccurate detection methods. Since changes in protein expression as well as modifications in protein glycosylation have been frequently reported in cancer development, the aim of this work was to study the differential expression as well as modifications of glycosylation of proteins from plasma of women with breast cancer at different stages of disease (n = 30) compared to healthy women (n = 10)...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28210411/carotid-cavernous-fistula-as-a-complication-of-panfacial-fracture-case-report-11-years-after-the-surgery
#5
Sylvio Luiz Costa de Moraes, Alexandre Maurity de Paula Afonso, Roberto Gomes Dos Santos, Ricardo Pereira Mattos, Bruno Gomes Duarte
The carotid-cavernous fistula (CCF) is a rare complication in patients victimized by craniofacial trauma. It involves multidisciplinary medical action. Owing to its potential complications, it is essential that maxillofacial surgery and neurosurgery specialists diagnose this condition so that appropriate treatment can be performed. The authors present a report of a case 11 years after the surgery.
March 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28210255/high-prevalence-of-gammaproteobacteria-in-the-sediments-of-admiralty-bay-and-north-bransfield-basin-northwestern-antarctic-peninsula
#6
Diego C Franco, Camila N Signori, Rubens T D Duarte, Cristina R Nakayama, Lúcia S Campos, Vivian H Pellizari
Microorganisms dominate most Antarctic marine ecosystems, in terms of biomass and taxonomic diversity, and play crucial role in ecosystem functioning due to their high metabolic plasticity. Admiralty Bay is the largest bay on King George Island (South Shetland Islands, Antarctic Peninsula) and a combination of hydro-oceanographic characteristics (bathymetry, sea ice and glacier melting, seasonal entrance of water masses, turbidity, vertical fluxes) create conditions favoring organic carbon deposition on the seafloor and microbial activities...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28209815/whole-genome-sequence-of-a-colombian-acinetobacter-baumannii-strain-a-coproducer-of-oxa-72-and-oxa-255-like-carbapenemases
#7
Sandra Yamile Saavedra, Diego Prada-Cardozo, Verónica Rincón, Hermes Pérez-Cardona, Andrea Melissa Hidalgo, María Nilse González, María T Reguero, Emilia M Valenzuela de Silva, José R Mantilla, Laurent Falquet, Emiliano Barreto-Hernández, Carolina Duarte
Colombian Acinetobacter baumannii strain ST920 was isolated from the sputum of a 68-year-old male patient. This isolate possessed blaOXA-72 and blaOXA-255-like genes. The assembled genome contained 4,104,098 pb and 38.79% G+C content. This is the first case reported of the coproduction (blaOXA-72 and blaOXA-255-like) of carbapenem-hydrolyzing class D β-lactamases (CHDLs) in Acinetobacter baumannii.
February 16, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28209442/the-maturation-state-of-the-auditory-nerve-and-brainstem-in-rats-exposed-to-lead-acetate-and-supplemented-with-ferrous-sulfate
#8
Fernanda Zucki, Thais C Morata, Josilene L Duarte, Maria Cecília F Ferreira, Manoel H Salgado, Kátia F Alvarenga
INTRODUCTION: The literature has reported the association between lead and auditory effects, based on clinical and experimental studies. However, there is no consensus regarding the effects of lead in the auditory system, or its correlation with the concentration of the metal in the blood. OBJECTIVE: To investigate the maturation state of the auditory system, specifically the auditory nerve and brainstem, in rats exposed to lead acetate and supplemented with ferrous sulfate...
January 23, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28208831/resveratrol-and-grape-extract-loaded-solid-lipid-nanoparticles-for-the-treatment-of-alzheimer-s-disease
#9
Joana A Loureiro, Stephanie Andrade, Ana Duarte, Ana Rute Neves, Joana Fontes Queiroz, Cláudia Nunes, Emmanuel Sevin, Laurence Fenart, Fabien Gosselet, Manuel A N Coelho, Maria Carmo Pereira
The aggregation of amyloid-β peptide (Aβ) has been linked to the formation of neuritic plaques, which are pathological hallmarks of Alzheimer's disease (AD). Various natural compounds have been suggested as therapeutics for AD. Among these compounds, resveratrol has aroused great interest due to its neuroprotective characteristics. Here, we provide evidence that grape skin and grape seed extracts increase the inhibition effect on Aβ aggregation. However, after intravenous injection, resveratrol is rapidly metabolized into both glucuronic acid and sulfate conjugations of the phenolic groups in the liver and intestinal epithelial cells (within less than 2 h), which are then eliminated...
February 13, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28202261/hyperprolinemia-as-a-clue-in-the-diagnosis-of-a-patient-with-psychiatric-manifestations
#10
Marco Duarte, Joana Afonso, Ana Moreira, Diana Antunes, Cristina Ferreira, Hildeberto Correia, Margarida Marques, Sílvia Sequeira
Lately, microdeletions of the 22q region, responsible for DiGeorge syndrome or velocardiofacial syndrome, have been increasingly related to neuropsychiatric disorders including schizophrenia and bipolar disorder. These manifestations seem to be related to certain genes located in the hemideleted region such as the proline dehydrogenase (PRODH) and the catechol-o-methyltransferase (COMT) genes. We describe a teenager who started his adolescent psychiatric care presenting cognitive impairment, irritable mood and aggressive behaviour with schizophrenia-like symptoms that scored 153 in the Positive and Negative Symptoms Scale (PANSS) assessment...
February 12, 2017: Brain & Development
https://www.readbyqxmd.com/read/28202179/effects-of-melatonin-in-rats-in-the-initial-third-stage-of-pregnancy-exposed-to-sub-lethal-doses-of-herbicides
#11
Lécio Leone de Almeida, Álvaro Aguiar Coelho Teixeira, Anísio Francisco Soares, Franklin Magliano da Cunha, Valdemiro Amaro da Silva, Leucio Duarte Vieira Filho, Valéria Wanderley-Teixeira
: Exposure to the herbicides Paraquat (PQ) and Roundup(®) may cause cell lesions due to an increase in oxidative stress levels in different biological systems, even in the reproductive system. OBJECTIVE: Evaluate the possible changes in reproductive parameters and hepatic, as well as its prevention by simultaneous application of melatonin. METHODS: Thirty-five female rats at the age of 3 months were divided into seven groups: three groups exposed to sub-lethal doses of the herbicides PQ (50mg/kg) and Roundup(®) (500mg/kg) (n=5, G2, G3 and G4); three groups exposed to herbicides and simultaneous treatment with 10mg/kg of Melatonin (n=5, G5, G6 and G7) and control group (n=5, G1) from the first to the seventh day of pregnancy...
February 12, 2017: Acta Histochemica
https://www.readbyqxmd.com/read/28202087/disability-adjusted-life-year-daly-of-central-line-bloodstream-infection-clabsi-in-a-university-hospital-in-a-developing-country-brazil
#12
Jaqueline Abel da Rocha, Fernanda Moreth do Valle, Natalia Chilinque Zambão da Silva, Ana Sheila Duarte Nunes Silva, Suzana Dos Santos Vaz, Wildo Navegantes de Araújo, Ianick Souto Martins
Central-line bloodstream infection (CLABSI) increases hospital mortality. A cohort study was conducted in a Brazilian hospital to estimate the disability-adjusted life year (DALY) of CLABSI using modified World Health Organization (WHO) methodology. CLABSI DALY was 20.44 per 1,000 inpatients, most were the result of premature death (20.42 per 1,000 inpatients). DALY can be useful to guide and measure the impact of healthcare infection prevention. Infect Control Hosp Epidemiol 2017;1-4.
February 16, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28201981/identification-of-effector-like-proteins-in-trichoderma-spp-and-role-of-a-hydrophobin-in-the-plant-fungus-interaction-and-mycoparasitism
#13
Paulina Guzmán-Guzmán, Mario Iván Alemán-Duarte, Luis Delaye, Alfredo Herrera-Estrella, Vianey Olmedo-Monfil
BACKGROUND: Trichoderma spp. can establish beneficial interactions with plants by promoting plant growth and defense systems, as well as, antagonizing fungal phytopathogens in mycoparasitic interactions. Such interactions depend on signal exchange between both participants and can be mediated by effector proteins that alter the host cell structure and function, allowing the establishment of the relationship. The main purpose of this work was to identify, using computational methods, candidates of effector proteins from T...
February 15, 2017: BMC Genetics
https://www.readbyqxmd.com/read/28199874/biodegradation-of-polyethylene-microplastics-by-the-marine-fungus-zalerion-maritimum
#14
Ana Paço, Kátia Duarte, João P da Costa, Patrícia S M Santos, R Pereira, M E Pereira, Ana C Freitas, Armando C Duarte, Teresa A P Rocha-Santos
Plastic yearly production has surpassed the 300milliontons mark and recycling has all but failed in constituting a viable solution for the disposal of plastic waste. As these materials continue to accumulate in the environment, namely, in rivers and oceans, in the form of macro-, meso-, micro- and nanoplastics, it becomes of the utmost urgency to find new ways to curtail this environmental threat. Multiple efforts have been made to identify and isolate microorganisms capable of utilizing synthetic polymers and recent results point towards the viability of a solution for this problem based on the biodegradation of plastics resorting to selected microbial strains...
February 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28199779/mechanoapi-ils-pharmaceutical-ionic-liquids-obtained-via-mechanochemical-synthesis
#15
Inês Martins, Conceição Oliveira, Hermínio Diogo, Luís Branco, Teresa Duarte
We report here, for the first time, an alternative, efficient and greener synthetic strategy for the preparation of pharmaceutical ionic liquids using mechanochemistry (MechanoAPI-ILs). Six new API-ILs based on gabapentin and L-glutamic acid were successfully synthesized and characterized pointing out that mechanochemistry is a challenging and very promising synthetic strategy. Results compare both the new and the classical approach and clearly show the advantages of the new method. This technique has shown to be faster, "solvent free", reproducible, selective and lead to higher yields...
February 15, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28198980/influence-of-glycemic-control-on-the-levels-of-subgingival-periodontal-pathogens-in-patients-with-generalized-chronic-periodontitis-and-type-2-diabetes
#16
Tamires Szeremeske Miranda, Magda Feres, Belén Retamal-Valdés, Paula Juliana Perez-Chaparro, Suellen Silva Maciel, Poliana Mendes Duarte
Objective: This study evaluated the influence of glycemic control on the levels and frequency of subgingival periodontal pathogens in patients with type 2 diabetes mellitus (DM) and generalized chronic periodontitis (ChP). Material and Methods: Fifty-six patients with generalized ChP and type 2 DM were assigned according to the levels of glycated hemoglobin (HbA1c) into one of the following groups: HbA1c<8% (n=28) or HbA1c≥8% (n=28). Three subgingival biofilm samples from sites with probing depth (PD)<5 mm and three samples from sites with PD≥5 mm were analyzed by quantitative Polymerase Chain Reaction (PCR) for the presence and levels of Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Eubacterium nodatum, Parvimona micra, Fusobacterium nucleatum ssp...
January 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28198973/influence-of-niti-alloy-on-the-root-canal-shaping-capabilities-of-the-protaper-universal-and-protaper-gold-rotary-instrument-systems
#17
Jussaro Alves Duque, Rodrigo Ricci Vivan, Bruno Cavalini Cavenago, Pablo Andrés Amoroso-Silva, Ricardo Affonso Bernardes, Bruno Carvalho de Vasconcelos, Marco Antonio Hungaro Duarte
Objective: This study aimed to evaluate the influence of the NiTi wire in Conventional NiTi (ProTaper Universal PTU) and Controlled Memory NiTi (ProTaper Gold PTG) instrument systems on the quality of root canal preparation. Material and Methods: Twelve mandibular molars with separate mesial canals were scanned using a high-definition microcomputed tomography system. The PTU and PTG instruments were used to shape twelve mesial canals each. The canals were scanned after preparation with F2 and F3 instruments of the PTU and PTG systems...
January 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28198211/both-n-methyl-d-aspartate-and-non-n-methyl-d-aspartate-glutamate-receptors-in-the-bed-nucleus-of-the-stria-terminalis-modulate-the-cardiovascular-responses-to-acute-restraint-stress-in-rats
#18
Mariane B Adami, Lucas Barretto-de-Souza, Josiane O Duarte, Jeferson Almeida, Carlos C Crestani
The bed nucleus of the stria terminalis (BNST) is a forebrain structure that has been implicated on cardiovascular responses evoked by emotional stress. However, the local neurochemical mechanisms mediating the BNST control of stress responses are not fully described. In our study we investigated the involvement of glutamatergic neurotransmission within the BNST in cardiovascular changes evoked by acute restraint stress in rats. For this study, we investigated the effects of bilateral microinjections of selective antagonists of either N-methyl-D-aspartate (NMDA) or non-NMDA glutamate receptors into the BNST on the arterial pressure and heart rate increase and the decrease in tail skin temperature induced by acute restraint stress...
February 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28197801/team-sports-performance-analysed-through-the-lens-of-social-network-theory-implications-for-research-and-practice
#19
João Ribeiro, Pedro Silva, Ricardo Duarte, Keith Davids, Júlio Garganta
This paper discusses how social network analyses and graph theory can be implemented in team sports performance analyses to evaluate individual (micro) and collective (macro) performance data, and how to use this information for designing practice tasks. Moreover, we briefly outline possible limitations of social network studies and provide suggestions for future research. Instead of cataloguing discrete events or player actions, it has been argued that researchers need to consider the synergistic interpersonal processes emerging between teammates in competitive performance environments...
February 15, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28196285/morphological-evaluation-of-maxillary-second-molars-with-fused-roots-a-micro-ct-study
#20
R Ordinola-Zapata, J N R Martins, C M Bramante, M H Villas-Boas, M H Duarte, M A Versiani
AIM: To evaluate the internal and external morphologies of fused-rooted maxillary second molars by means of micro-computed tomography (micro-CT) analysis. METHODOLOGY: One-hundred fused-rooted maxillary second molars from a Brazilian subpopulation were divided into six groups according to the root morphology. The samples were scanned at a resolution of 19.6 μm, and evaluated with regards to the external morphology of the roots, the root canal configuration, the percentage frequency of C-shaped canals and isthmuses, as well as, the morphology of the root canal system at 1, 2 and 3 mm from the anatomic apex of the fused roots...
February 14, 2017: International Endodontic Journal
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