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https://www.readbyqxmd.com/read/28727943/the-genetic-background-of-metabolic-trait-clusters-in-children-and-adolescents
#1
Karri Silventoinen, Élvio Gouveia, Aline Jelenkovic, José Maia, António M Antunes, Miguel A A Pinheiro de Carvalho, António M Brehm, Martine Thomis, Johan Lefevre, Jaakko Kaprio, Duarte Freitas
BACKGROUND: It is well known that metabolic risk factors of cardiovascular diseases are correlated, but the background of this clustering in children is more poorly known than in adults. Thus, we studied the contribution of genetic and environmental factors to the clustering of metabolic traits in childhood and adolescence. DATA AND METHODS: Nine metabolic traits were measured in 214 complete twin pairs aged 3-18 years in the Autonomous Region of Madeira, Portugal, in 2007 and 2008...
July 20, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28727019/triennial-growth-and-development-symposium-dedifferentiated-fat-cells-potential-and-perspectives-for-their-use-in-clinical-and-animal-science-purpose
#2
M S Duarte, R Bueno, W Silva, C F Campos, M P Gionbelli, S E F Guimarães, F F Silva, P S Lopes, G J Hausman, M V Dodson
An increasing body of evidences has demonstrated the ability of the mature adipocyte to dedifferentiate into a population of proliferative-competent cells known as dedifferentiated fat (DFAT) cells. As early as the 1970s, in vitro studies showed that DFAT cells may be obtained by ceiling culture, which takes advantage of the buoyancy property of lipid-filled cells. It was documented that DFAT cells may acquire a phenotype similar to mesenchymal stem cells and yet may differentiate into multiple cell lineages, such as skeletal and smooth muscle cells, cardiomyocytes, osteoblasts, and adipocytes...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726179/methionine-and-or-methionine-sulfoxide-alter-ectoenzymes-activities-in-lymphocytes-and-inflammatory-parameters-in-serum-from-young-rats-acute-and-chronic-effects
#3
Mayara Sandrielly Pereira Soares, Marcelo Zanusso Costa, Tatiane Morgana da Silva, Marta Gazal, Carlus Augustu Tavares do Couto, Gabriela Nogueira Debom, Rodrigo Rodrigues, Juliana Hofstätter Azambuja, Emerson André Casali, Cesar Eduardo Jacintho Moritz, Marta Frescura Duarte, Elizandra Braganhol, Francieli Moro Stefanello, Roselia Maria Spanevello
In this study we investigated the effect of acute and chronic treatment with Met and/or methionine sulfoxide (MetO) on ectonucleotidases and cholinesterases activities from lymphocytes and purine derivatives compounds, C-protein reactive, interleukin-10, interleukin-6, and tumor necrosis factor-α levels in serum of young rats. Adenosine triphosphate hydrolysis was decreased in lymphocytes 1 h after treatment by MetO and Met + MetO. However, adenosine triphosphate and adenosine diphosphate hydrolysis in lymphocytes was increased in the groups MetO and Met + MetO and adenosine deaminase activity was increased in MetO 3 h after the treatment...
July 19, 2017: Cell Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28725561/bronchopleural-and-pleurocutaneous-fistula-in-hiv-patient-with-pulmonary-tuberculosis
#4
Filipa Duarte-Ribeiro, Cátia Dias, Margarida Mota
We present a 37-year-old man intravenous drug user, with HIV/HCV/HBV co-infection, lymph node tuberculosis 10 years before (completed 12 months of treatment), and left lobar pneumonia 4 years earlier complicated by empyema (treated with left lower lobectomy with a persistent bronchopleural fistula) who was admitted to the emergency department with caseous-purulent drainage and exteriorization of air from an orifice in the chest wall. Acid-fast bacilli were identified in this drainage. A pleurocutaneous fistula was evident on the chest computed tomography scan...
2017: IDCases
https://www.readbyqxmd.com/read/28725500/volar-plate-fixation-in-patients-older-than-70-years-with-ao-type-c-distal-radial-fractures-clinical-and-radiologic-outcomes
#5
Nicolas S Piuzzi, Ezequiel E Zaidenberg, Matias Pereira Duarte, Jorge G Boretto, Agustin Donndorff, Gerardo Gallucci, Pablo De Carli
Introduction  Treatment of unstable distal radial fractures (DRFs) in elderly patients is controversial, and considering the increasing life expectancy, their appropriate treatment is of growing importance. Our aim was to analyze the clinical and radiologic outcomes in the elderly patients with AO type C DRF treated with volar locking plate (VLP). Materials and Methods  Between 2007 and 2011, 572 DRFs were operated on in our hospital with open reduction and internal fixation with VLP. Of these, only 64 patients (66 DRFs) met the selection criteria (AO type C DRF, age > 70 years, minimum 12-month follow-up)...
August 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28724970/classification-of-skin-phenotypes-caused-by-diabetes-mellitus-using-complex-scattering-parameters-in-the-millimeter-wave-frequency-range
#6
Fabian Dornuf, Pedro Martín-Mateos, Blanca Duarte, Bernhard Hils, Oscar Elias Bonilla-Manrique, Fernando Larcher, Pablo Acedo, Viktor Krozer
The pathological skin phenotype caused by hyperglycemia is an important indicator for the progress of diabetes mellitus. An early detection of diabetes assures an early intervention to regulate the carbohydrate metabolism. In this publication a non-invasive detection principle based on the measurement of complex scattering parameters in the millimeter-wave frequency range is presented. The measurement principle provides evidence of the applicability for the identification of different glycemic states in animal models...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724040/cardiac-remodeling-indicators-in-adolescent-athletes
#7
Joaquim Castanheira, João Valente-Dos-Santos, Daniela Costa, Diogo Martinho, Jorge Fernandes, João Duarte, Nuno Sousa, Vasco Vaz, Luis Rama, António Figueiredo, Manuel Coelho-E-Silva
Objective: The idea that different sports and physical training type results in different cardiac adaptations has been widely accepted. However, this remodelling process among different sport modalities is still not fully understood. Thus, the current study aims to investigate the heart morphology variation associated with a set of different modalities characterized by distinct models of preparation and different methods and demands of training and completion. Method: The sample comprises 42 basketball players, 73 roller hockey players, 28 judo athletes and 21 swimmers...
May 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28724037/impact-of-biological-therapy-on-body-composition-of-patients-with-chron-s-disease
#8
Julianne Campos Dos Santos, Carla Malaguti, Fernando de Azevedo Lucca, Andrea Lemos Cabalzar, Tarsila Campanha da Rocha Ribeiro, Pedro Duarte Gaburri, Liliana Andrade Chebli, Julio Maria Fonseca Chebli
Introduction: Protein-energy malnutrition in Crohn's disease (CD) has been reported in 20 to 92% of patients, and is associated with increased morbidity and mortality and higher costs for the health system. Anti-TNF drugs are a landmark in the clinical management, promoting prolonged remission in patients with CD. It is believed that the remission of this disease leads to nutritional recovery. The effect of biological therapy on body composition and nutritional status is unclear. Method: Prospective study of body assessment by bioelectrical impedance method in patients with moderate to severe CD undergoing treatment with infliximab...
May 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28723892/global-forest-loss-disproportionately-erodes-biodiversity-in-intact-landscapes
#9
Matthew G Betts, Christopher Wolf, William J Ripple, Ben Phalan, Kimberley A Millers, Adam Duarte, Stuart H M Butchart, Taal Levi
Global biodiversity loss is a critical environmental crisis, yet the lack of spatial data on biodiversity threats has hindered conservation strategies. Theory predicts that abrupt biodiversity declines are most likely to occur when habitat availability is reduced to very low levels in the landscape (10-30%). Alternatively, recent evidence indicates that biodiversity is best conserved by minimizing human intrusion into intact and relatively unfragmented landscapes. Here we use recently available forest loss data to test deforestation effects on International Union for Conservation of Nature Red List categories of extinction risk for 19,432 vertebrate species worldwide...
July 19, 2017: Nature
https://www.readbyqxmd.com/read/28720787/comparison-between-an-african-town-and-a-neighbouring-village-shows-delayed-but-not-decreased-sleep-during-the-early-stages-of-urbanisation
#10
Andrew D Beale, Mario Pedrazzoli, Bruno da Silva B Gonçalves, Felipe Beijamini, Núbia E Duarte, Kieren J Egan, Kristen L Knutson, Malcolm von Schantz, Laura C Roden
The well-established negative health outcomes of sleep deprivation, and the suggestion that availability of electricity may enable later bed times without compensating sleep extension in the morning, have stimulated interest in studying communities whose sleep pattern may resemble a pre-industrial state. Here, we describe sleep and activity in two neighbouring communities, one urban (Milange) and one rural (Tengua), in a region of Mozambique where urbanisation is an ongoing process. The two communities differ in the amount and timing of daily activity and of light exposure, with later bedtimes (≈1 h) associated with more evening and less daytime light exposure seen in the town of Milange...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28720489/simplified-membrane-feeding-of-bloodsucking-triatomines-hemiptera-reduviidae
#11
Glennyha F Duarte, Dayane B Macedo, Christian Luz
Laboratory-reared hematophagous triatomines that are the main vectors of Chagas disease are generally fed on small vertebrates or on blood-filled membrane devices. Such devices allow a large-scale rearing of these vectors without sacrificing host animals but are almost always expensive, fragile, not easily purchased, and usually difficult to use because they need to be sterilized before and carefully cleaned after each feeding. We present here a simple device to feed triatomines that is composed of a circular series of alternating short pieces of stainless steel and silicon tubing connected to a pump that circulates water heated at 50° C in a water bath...
July 15, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28720438/on-the-utility-of-3d-hand-cursors-to-explore-medical-volume-datasets-with-a-touchless-interface
#12
Daniel Simões Lopes, Pedro Duarte de Figueiredo Parreira, Soraia Figueiredo Paulo, Vitor Nunes, Paulo Amaral Rego, Manuel Cassiano Neves, Pedro Silva Rodrigues, Joaquim Armando Jorge
Analyzing medical volume datasets requires interactive visualization so that users can extract anatomo-physiological information in real-time. Conventional volume rendering systems rely on 2D input devices, such as mice and keyboards, which are known to hamper 3D analysis as users often struggle to obtain the desired orientation that is only achieved after several attempts. In this paper, we address which 3D analysis tools are better performed with 3D hand cursors operating on a touchless interface comparatively to a 2D input devices running on a conventional WIMP interface...
July 15, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28719937/a-challenging-case-of-giant-biliary-stones-in-a-patient-with-situs-inversus-totalis-conventional-ercp-combined-with-intraductal-cholangioscopy-and-laser-lithotripsy
#13
Félix I Téllez-Ávila, Sandeep Pattel, Gilberto Duarte-Medrano, Marlon Seenath, David R Herrera-Mora, Gustavo Lopez-Arce
No abstract text is available yet for this article.
July 18, 2017: Endoscopy
https://www.readbyqxmd.com/read/28719924/erratum-decontamination-of-mikania-glomerata-leaves-by-gamma-irradiation-coumarin-determination-by-hplc-dad-microbiological-control-and-genotoxicological-studies
#14
Marcos Martins Gouvêa, Samara Cristina Ferreira-Machado, Thalita Martins da Silva, Julien Silva Lima, Cláudio Sérgio Corrêa Lau, Luciana Maria Ramires Esper, Samanta Cardozo Mourão, Elizabeth Valverde Macedo, Helio de Carvalho Vital, Edson Ramos Andrade, Annibal Duarte Pereira Netto, Flávia Ferreira de Carvalho Marques, Carlos Augusto de Freitas Peregrino
No abstract text is available yet for this article.
July 18, 2017: Planta Medica
https://www.readbyqxmd.com/read/28719634/taxa-area-relationship-of-aquatic-fungi-on-deciduous-leaves
#15
Sofia Duarte, Fernanda Cássio, Cláudia Pascoal, Felix Bärlocher
One of the fundamental patterns in macroecology is the increase in the number of observed taxa with size of sampled area. For microbes, the shape of this relationship remains less clear. The current study assessed the diversity of aquatic fungi, by the traditional approach based on conidial morphology (captures reproducing aquatic hyphomycetes) and next generation sequencing (NGS; captures other fungi as well), on graded sizes of alder leaves (0.6 to 13.6 cm2). Leaves were submerged in two streams in geographically distant locations: the Oliveira Stream in Portugal and the Boss Brook in Canada...
2017: PloS One
https://www.readbyqxmd.com/read/28719614/beat-id-towards-a-computationally-low-cost-single-heartbeat-biometric-identity-check-system-based-on-electrocardiogram-wave-morphology
#16
Joana S Paiva, Duarte Dias, João P S Cunha
In recent years, safer and more reliable biometric methods have been developed. Apart from the need for enhanced security, the media and entertainment sectors have also been applying biometrics in the emerging market of user-adaptable objects/systems to make these systems more user-friendly. However, the complexity of some state-of-the-art biometric systems (e.g., iris recognition) or their high false rejection rate (e.g., fingerprint recognition) is neither compatible with the simple hardware architecture required by reduced-size devices nor the new trend of implementing smart objects within the dynamic market of the Internet of Things (IoT)...
2017: PloS One
https://www.readbyqxmd.com/read/28719026/in-vitro-antiproliferative-and-antibacterial-activities-of-essential-oils-from-four-species-of-guatteria
#17
Anderson R Santos, Thalita Gilda S Benghi, Angelita Nepel, Francisco A Marques, Adriana Q Lobão, Marta Cristina T Duarte, Ana Lúcia T G Ruiz, João E Carvalho, Beatriz H L N S Maia
The essential oils extracted from four species of the genus Guatteria, G.australis, G. ferruginea, G. latifolia and G. sellowiana were analyzed. A total of 24, 22, 25 and 19 constituents of the oils from four species, respectively, were identified by GC-MS. These oils showed qualitative and quantitative differences. All the oils contained the oxygenated sesquiterpenes spathulenol (11.04 - 40.29%) and caryophyllene oxide (7.74 - 40.13%) as predominant constituents. Evaluation of antiproliferative activity of the essential oils showed strong selectivity (1...
July 18, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28718933/treatment-of-hidradenitis-suppurativa-with-rifampicin-have-we-forgotten-tuberculosis
#18
P Mendes-Bastos, R Macedo, R Duarte
Hidradenitis suppurativa (HS) is a chronic, recurrent and debilitating skin disease of the hair follicle that is accompanied by systemic inflammation. Treating HS is challenging, and therapeutic tools as diverse as topical and systemic antibiotics, biologics, intralesional steroids, surgical procedures or light and laser therapies are frequently needed. The combination of oral clindamycin and rifampicin (R+C) has been suggested as a possible treatment regimen (level of evidence III, strength of recommendation C)...
July 18, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28718496/-introduction-of-rapid-syphilis-and-hiv-testing-in-prenatal-care-in-colombia-qualitative-analysis
#19
María Teresa Ochoa-Manjarrés, Hernando Guillermo Gaitán-Duarte, Sidia Caicedo, Berta Gómez, Freddy Pérez
Objective: Interpret perceptions of Colombian health professionals concerning factors that obstruct and facilitate the introduction of rapid syphilis and HIV testing in prenatal care services. Methods: A qualitative study based on semi-structured interviews was carried out. A convenience sample was selected with 37 participants, who included health professionals involved in prenatal care services, programs for pregnant women, clinical laboratories, and directors of health care units or centers, as well as representatives from regional departments and the Ministry of Health...
December 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28718495/comparative-effectiveness-of-single-and-dual-rapid-diagnostic-tests-for-syphilis-and-hiv-in-antenatal-care-services-in-colombia
#20
Hernando Guillermo Gaitán-Duarte, Lori Newman, Maura Laverty, Ndema Abu Habib, Lina María González-Gordon, Edith Ángel-Müller, Catleya Abella, Esther Cristina Barros, Carlos Rincón, Sidia Caicedo, Bertha Gómez, Freddy Pérez
Objective: To assess the effectiveness of a dual rapid test compared to a single rapid test for syphilis and HIV screening. Methods: A cluster-randomized open-label clinical trial was performed in 12 public antenatal care (ANC) centers in the cities of Bogotá and Cali, Colombia. Pregnant women who were over 14 years of age at their first antenatal visit and who had not been previously tested for HIV and syphilis during the current pregnancy were included. Pregnant women were randomized to single HIV and single syphilis rapid diagnostic tests (Arm A) or to dual HIV and syphilis rapid diagnostic tests (Arm B)...
December 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
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