keyword
MENU ▼
Read by QxMD icon Read
search

biomedicine

keyword
https://www.readbyqxmd.com/read/28229106/neonatal-corticosterone-administration-in-rodents-as-a-tool-to-investigate-the-maternal-programming-of-emotional-and-immune-domains
#1
Simone Macrì
Neonatal experiences exert persistent influences on individual development. These influences encompass numerous domains including emotion, cognition, reactivity to external stressors and immunity. The comprehensive nature of the neonatal programming of individual phenotype is reverberated in the large amount of experimental data collected by many authors in several scientific fields: biomedicine, evolutionary and molecular biology. These data support the view that variations in precocious environmental conditions may calibrate the individual phenotype at many different levels...
February 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28227434/electrospinning-of-gelatin-and-smpu-with-carbon-nanotubes-for-tissue-engineering-scaffolds
#2
Monica A Mejia, Lina M Hoyos, Jenniffer Zapata, Luz M Restrepo, Maria E Moneada, Monica A Mejia, Lina M Hoyos, Jenniffer Zapata, Luz M Restrepo, Maria E Moneada, Lina M Hoyos, Jenniffer Zapata, Monica A Mejia, Luz M Restrepo
The nanofibres created by electrospinning technique are currently used for a variety of applications in tissue engineering; and Gelatin and Polyurethane Shape-Memory (SMPU) have important results in biomedicine. Similarly, carbon nanotubes combined with other biomaterials change important properties, opening new opportunities for biomedical applications. In this work, we constructed scaffold using electrospinning technique based in bovine-hide gelatin, SMPU and both materials hybrid with carbon nanotube. Morphology and cytotoxicity were evaluated and mechanical properties for two materials were obtained in scaffold building...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226421/opening-plenary-speaker-human-genomics-precision-medicine-and-advancing-human-health
#3
Eric D Green
Starting with the launch of the Human Genome Project in 1990, the past quarter-century has brought spectacular achievements in genomics that dramatically empower the study of human biology and disease. The human genomics enterprise is now in the midst of an important transition, as the growing foundation of genomic knowledge is being used by researchers and clinicians to tackle increasingly complex problems in biomedicine. Of particular prominence is the use of revolutionary new DNA sequencing technologies for generating prodigious amounts of DNA sequence data to elucidate the complexities of genome structure, function, and evolution, as well as to unravel the genomic bases of rare and common diseases...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225160/emerging-low-dimensional-materials-for-nonlinear-optics-and-ultrafast-photonics
#4
REVIEW
Xiaofeng Liu, Qiangbing Guo, Jianrong Qiu
Low-dimensional (LD) materials demonstrate intriguing optical properties, which lead to applications in diverse fields, such as photonics, biomedicine and energy. Due to modulation of electronic structure by the reduced structural dimensionality, LD versions of metal, semiconductor and topological insulators (TIs) at the same time bear distinct nonlinear optical (NLO) properties as compared with their bulk counterparts. Their interaction with short pulse laser excitation exhibits a strong nonlinear character manifested by NLO absorption, giving rise to optical limiting or saturated absorption associated with excited state absorption and Pauli blocking in different materials...
February 22, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28218947/biomedicine-in-an-unstable-place-infrastructure-and-personhood-in-a-papua-new-guinean-hospital
#5
William Cayley
No abstract text is available yet for this article.
February 2017: Family Medicine
https://www.readbyqxmd.com/read/28216369/role-of-socio-cultural-and-economic-factors-in-cyprinid-fish-distribution-networks-and-consumption-in-lawa-lake-region-northeast-thailand-novel-perspectives-on-opisthorchis-viverrini-transmission-dynamics
#6
Christina Sunyoung Kim, John F Smith, Apiporn Suwannatrai, Pierre Echaubard, Bruce Wilcox, Sasithorn Kaewkes, Paiboon Sithithaworn, Banchob Sripa
Opisthorchis viverrini (Ov) is a fish-borne parasite endemic in parts of Lao PDR, Cambodia, southern Vietnam and Northeast Thailand (Isaan) where an estimated 10 million people are infected. Human Ov infection, associated with hepatobiliary complications, including cholangiocarcinoma (CCA), occurs when infected fish are consumed raw or undercooked, a longstanding cultural tradition in the region. This mixed- methods descriptive study was carried out in Isaan villages around Lawa Lake, Khon Kaen Province, known for their Ov endemicity...
February 16, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28216297/high-water-content-and-resilient-peg-containing-hydrogels-with-low-fibrotic-response
#7
Yu Zhang, Duo An, Yehudah Pardo, Alan Chiu, Wei Song, Qingsheng Liu, Fang Zhou, Sean P McDonough, Minglin Ma
: Hydrogels such as those based on polyethylene glycol (PEG) are broadly used in biomedicine where high water contents, robust mechanical properties such as resilience and favorable interactions with the body are often simultaneously desirable. However, the mechanical properties of conventional hydrogels often degrade rapidly after swelling or with increasing water content, limiting their potential in many applications. Here we describe a new class of PEG-containing hydrogels that remain highly resilient after maximum swelling...
February 16, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28211541/antibody-controlled-actuation-of-dna-based-molecular-circuits
#8
Wouter Engelen, Lenny H H Meijer, Bram Somers, Tom F A de Greef, Maarten Merkx
DNA-based molecular circuits allow autonomous signal processing, but their actuation has relied mostly on RNA/DNA-based inputs, limiting their application in synthetic biology, biomedicine and molecular diagnostics. Here we introduce a generic method to translate the presence of an antibody into a unique DNA strand, enabling the use of antibodies as specific inputs for DNA-based molecular computing. Our approach, antibody-templated strand exchange (ATSE), uses the characteristic bivalent architecture of antibodies to promote DNA-strand exchange reactions both thermodynamically and kinetically...
February 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/28211363/nanowire-networks-and-hollow-nanospheres-of-ag-au-bimetallic-alloys-at-room-temperature
#9
R Britto Hurtado, M Cortez-Valadez, H Arizpe-Chávez, N S Flores-Lopez, Ramón A B Álvarez, M Flores-Acosta
Due to their physicochemical properties, metallic nanoalloys have potential applications in biomedicine, electrocatalysis and electrochemical sensors, among many other fields. New alternative procedures have emerged in order to reduce production costs and the use of toxic substances. In this study we present a novel low-toxicity synthesis method for the fabrication of nanowire networks (NWNs) and Ag-Au hollow nanospheres. The synthesis process is performed at room temperature without any sophisticated equipment, such as special cameras or furnaces, etc...
March 17, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28199083/shape-memory-hydrogels-evolution-of-structural-principles-to-enable-shape-switching-of-hydrophilic-polymer-networks
#10
Candy Löwenberg, Maria Balk, Christian Wischke, Marc Behl, Andreas Lendlein
The ability of hydrophilic chain segments in polymer networks to strongly interact with water allows the volumetric expansion of the material and formation of a hydrogel. When polymer chain segments undergo reversible hydration depending on environmental conditions, smart hydrogels can be realized, which are able to shrink/swell and thus alter their volume on demand. In contrast, implementing the capacity of hydrogels to switch their shape rather than volume demands more sophisticated chemical approaches and structural concepts...
February 15, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28198395/real-time-broadband-terahertz-spectroscopic-imaging-by-using-a-high-sensitivity-terahertz-camera
#11
Natsuki Kanda, Kuniaki Konishi, Natsuki Nemoto, Katsumi Midorikawa, Makoto Kuwata-Gonokami
Terahertz (THz) imaging has a strong potential for applications because many molecules have fingerprint spectra in this frequency region. Spectroscopic imaging in the THz region is a promising technique to fully exploit this characteristic. However, the performance of conventional techniques is restricted by the requirement of multidimensional scanning, which implies an image data acquisition time of several minutes. In this study, we propose and demonstrate a novel broadband THz spectroscopic imaging method that enables real-time image acquisition using a high-sensitivity THz camera...
February 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28198384/hyperspectral-infrared-nanoimaging-of-organic-samples-based-on-fourier-transform-infrared-nanospectroscopy
#12
Iban Amenabar, Simon Poly, Monika Goikoetxea, Wiwat Nuansing, Peter Lasch, Rainer Hillenbrand
Infrared nanospectroscopy enables novel possibilities for chemical and structural analysis of nanocomposites, biomaterials or optoelectronic devices. Here we introduce hyperspectral infrared nanoimaging based on Fourier transform infrared nanospectroscopy with a tunable bandwidth-limited laser continuum. We describe the technical implementations and present hyperspectral infrared near-field images of about 5,000 pixel, each one covering the spectral range from 1,000 to 1,900 cm(-1). To verify the technique and to demonstrate its application potential, we imaged a three-component polymer blend and a melanin granule in a human hair cross-section, and demonstrate that multivariate data analysis can be applied for extracting spatially resolved chemical information...
February 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/28195163/targeted-gene-knock-in-by-crispr-cas-ribonucleoproteins-in-porcine-zygotes
#13
Ki-Eun Park, Anne Powell, Shelley E S Sandmaier, Chan-Mi Kim, Alan Mileham, David M Donovan, Bhanu P Telugu
The domestic pig is an important "dual purpose" animal model for agricultural and biomedical applications. There is an emerging consensus in the biomedical community for the use of large animal models such as pigs to either serve as an alternative, or complement investigations from the mouse. However, the use of pig has not proven popular due to technical difficulties and time required in generating models with desired genetic modifications. In this regard, the ability to directly modify the genome in the zygote and generate edited animals is highly desirable...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28192289/sensing-temperature-via-downshifting-emissions-of-lanthanide-doped-metal-oxides-and-salts-a-review
#14
Miroslav D Dramićanin
Temperature is important because it has an effect on even the tiniest elements of daily life and is involved in a broad spectrum of human activities. That is why it is the most commonly measured physical quantity. Traditional temperature measurements encounter difficulties when used in some emerging technologies and environments, such as nanotechnology and biomedicine. The problem may be alleviated using optical techniques, one of which is luminescence thermometry. This paper reviews the state of luminescence thermometry and presents different temperature read-out schemes with an emphasis on those utilizing the downshifting emission of lanthanide-doped metal oxides and salts...
October 11, 2016: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28191701/near-infrared-light-and-ph-dual-responsive-targeted-drug-carrier-based-on-core-crosslinked-polyaniline-nanoparticles-for-intracellular-delivery-of-cisplatin
#15
Chaoqun You, Hongshui Wu, Mingxin Wang, Yawen Zhang, Jingwen Wang, Yanghui Luo, Lihai Zhai, Bai-Wang Sun, Xiangyang Zhang, Jin Zhu
Biodegradable polymeric nanoparticles have caused a rapidly growing interest as one of the most promising agents applied to drug delivery. Functional and core crosslinked poly (ethylene glycol) with poly (ε-caprolactone) (PEG5k-PCL10k) block copolymer and lecithin as biodegradable polymer doping polyaniline to assemble nanoparticles which were prepared at present work for targeted delivery and controlled release of cisplatin as a common anti-tumor drug. The morphology of polyaniline nanoparticles were determined by dynamic light scattering and the prepared nanoparticles show a suitable size of 83±1 nm and a uniform spherical shape...
February 13, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28187301/the-preparation-of-dual-functional-hybrid-nanoflower-and-its-application-in-the-ultrasensitive-detection-of-disease-related-biomarker
#16
Yucheng Liu, Jinyang Chen, Mingyuan Du, Xinxin Wang, Xinghu Ji, Zhike He
In this work, dual-functional streptavidin (SA)-horseradish peroxidase (HRP) hybrid nanoflowers, integrating the functions of biological recognition and signal amplification, were prepared through facile one-pot green synthesis method. The prepared SA-HRP-Cu3(PO4)2 hybrid nanoflowers loaded abundant HRP and simultaneously exhibited enhanced catalytic activity, stability, and durability compared with free enzyme, which fits greatly well with the requirement of signal tag for bioassay. Besides, due to the general SA-biotin linking interaction, the SA-HRP-Cu3(PO4)2 hybrid nanoflowers possess universal capture ability to the biotinylated antibody...
February 4, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28186408/functional-microgels-and-microgel-systems
#17
Felix A Plamper, Walter Richtering
Microgels are macromolecular networks swollen by the solvent in which they are dissolved. They are unique systems that are distinctly different from common colloids, such as, e.g., rigid nanoparticles, flexible macromolecules, micelles, or vesicles. The size of the microgel networks is in the range of several micrometers down to nanometers (then sometimes called "nanogels"). In a collapsed state, they might resemble hard colloids but they can still contain significant amounts of solvent. When swollen, they are soft and have a fuzzy surface with dangling chains...
February 10, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28186367/localized-synthesis-of-iron-oxide-nanowires-and-fabrication-of-high-performance-nanosensors-based-on-a-single-fe2-o3-nanowire
#18
O Lupan, V Postica, N Wolff, O Polonskyi, V Duppel, V Kaidas, E Lazari, N Ababii, F Faupel, L Kienle, R Adelung
A composed morphology of iron oxide microstructures covered with very thin nanowires (NWs) with diameter of 15-50 nm has been presented. By oxidizing metallic Fe microparticles at 255 °C for 12 and 24 h, dense iron oxide NW networks bridging prepatterned Au/Cr pads are obtained. X-ray photoelectron spectroscopy studies reveal formation of α-Fe2 O3 and Fe3 O4 on the surface and it is confirmed by detailed high-resolution transmission electron microscopy and selected area electron diffraction (SAED) investigations that NWs are single phase α-Fe2 O3 and some domains of single phase Fe3 O4 ...
February 10, 2017: Small
https://www.readbyqxmd.com/read/28181831/basic-concepts-and-recent-advances-in-nanogels-as-carriers-for-medical-applications
#19
Iordana Neamtu, Alina Gabriela Rusu, Alina Diaconu, Loredana Elena Nita, Aurica P Chiriac
Nanogels in biomedical field are promising and innovative materials as dispersions of hydrogel nanoparticles based on crosslinked polymeric networks that have been called as next generation drug delivery systems due to their relatively high drug encapsulation capacity, uniformity, tunable size, ease of preparation, minimal toxicity, stability in the presence of serum, and stimuli responsiveness. Nanogels show a great potential in chemotherapy, diagnosis, organ targeting and delivery of bioactive substances...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28177282/cilia-mediated-hedgehog-signaling-controls-form-and-function-in-the-mammalian-larynx
#20
Jacqueline M Tabler, Maggie M Rigney, Gordon J Berman, Swetha Gopalakrishnan, Eglantine Heude, Hadeel A Al-Lami, Basil Z Yannakoudakis, Rebecca D Fitch, Christopher M Carter, Steven A Vokes, Karen J Liu, Shahragim Tajbakhsh, Se Roian Egnor, John B Wallingford
Acoustic communication is fundamental to social interactions among animals, including humans. In fact, deficits in voice impair the quality of life for a large and diverse population of patients. Understanding the molecular genetic mechanisms of development and function in the vocal apparatus is thus an important challenge with relevance both to the basic biology of animal communication and to biomedicine. However, surprisingly little is known about the developmental biology of the mammalian larynx. Here, we used genetic fate mapping to chart the embryological origins of the tissues in the mouse larynx, and we describe the developmental etiology of laryngeal defects in mice with disruptions in cilia-mediated Hedgehog signaling...
February 8, 2017: ELife
keyword
keyword
108705
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"