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https://www.readbyqxmd.com/read/28815433/new-insights-on-the-green-synthesis-of-metallic-nanoparticles-using-plant-and-waste-biomaterials-current-knowledge-their-agricultural-and-environmental-applications
#1
Rijuta Ganesh Saratale, Ganesh Dattatraya Saratale, Han Seung Shin, Jaya Mary Jacob, Arivalagan Pugazhendhi, Mukesh Bhaisare, Gopalakrishanan Kumar
Nanotechnology is a rapidly growing scientific field and has attracted a great interest over the last few years because of its abundant applications. Green nanotechnology is a multidisciplinary field that has emerged as a rapidly developing research area, serving as an important technique that emphasize on making the procedure which are clean, non-hazardous, and especially environmentally friendly, in contrast with chemical and physical methods currently employed for nanosynthesis. The biogenic routes could be termed green as these do not involve the use of highly toxic chemicals or elevated energy inputs during the synthesis...
August 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28815155/segmentation-of-phase-contrast-microscopy-images-based-on-multi-scale-local-basic-image-features-histograms
#2
N Jaccard, N Szita, L D Griffin
Phase contrast microscopy (PCM) is routinely used for the inspection of adherent cell cultures in all fields of biology and biomedicine. Key decisions for experimental protocols are often taken by an operator based on typically qualitative observations. However, automated processing and analysis of PCM images remain challenging due to the low contrast between foreground objects (cells) and background as well as various imaging artefacts. We propose a trainable pixel-wise segmentation approach whereby image structures and symmetries are encoded in the form of multi-scale Basic Image Features local histograms, and classification of them is learned by random decision trees...
September 3, 2017: Computer Methods in Biomechanics and Biomedical Engineering. Imaging & Visualization
https://www.readbyqxmd.com/read/28814149/n-implantation-induce-cytocompatibility-of-shape-controlled-three-dimensional-self-assembly-graphene
#3
Ye Cao, Dejun Li, Mengli Zhao, Huanhuan Gong, Rongxin Wan, Hanqing Gu
AIM: The aim of the present research was to synthesize N(+) implanted 3D self-assembly graphene (N(+)/3D-SGHs) to overcome the weaknesses of graphene (small sizes and poor hydrophilicity) in tissue engineering scaffolds. MATERIALS & METHODS: N(+)/3D-SGHs was achieved by ion implantation on one-step hydrothermal synthesized 3D self-assembly graphene (3D-SGHs), and N(+)/3D-SGHs with different doses of nitrogen ions (1 × 10(16) ions/cm(2), 1 × 10(18) ions/cm(2) and 1 × 10(20) ions/cm(2)), which adjusted by nitrogen ion beam intensity...
August 17, 2017: Nanomedicine
https://www.readbyqxmd.com/read/28811610/antibiotic-induced-release-of-small-extracellular-vesicles-exosomes-with-surface-associated-dna
#4
Andrea Németh, Norbert Orgovan, Barbara W Sódar, Xabier Osteikoetxea, Krisztina Pálóczi, Katalin É Szabó-Taylor, Krisztina V Vukman, Ágnes Kittel, Lilla Turiák, Zoltán Wiener, Sára Tóth, László Drahos, Károly Vékey, Robert Horvath, Edit I Buzás
Recently, biological roles of extracellular vesicles (which include among others exosomes, microvesicles and apoptotic bodies) have attracted substantial attention in various fields of biomedicine. Here we investigated the impact of sustained exposure of cells to the fluoroquinolone antibiotic ciprofloxacin on the released extracellular vesicles. Ciprofloxacin is widely used in humans against bacterial infections as well as in cell cultures against Mycoplasma contamination. However, ciprofloxacin is an inducer of oxidative stress and mitochondrial dysfunction of mammalian cells...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810451/the-pre-history-of-health-psychology-in-the-united-kingdom-from-natural-science-and-psychoanalysis-to-social-science-social-cognition-and-beyond
#5
Michael Murray
Health psychology formally came of age in the United Kingdom in the 1980s, but it was prefigured by much discussion about challenges to the dominance of biomedicine in healthcare and debates about the role of individual behaviour change in promoting population health. Despite current progress and accomplishments, it is important to reflect upon earlier attempts to explore the psychological dimensions of health and illness. It is through such exploration that we can begin to reveal the connection between ideas and the social context...
May 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28809087/spontaneous-reporting-of-suspected-narcolepsy-after-vaccination-against-pandemic-influenza-a-h1n1-in-germany
#6
Doris Oberle, Jutta Pavel, Brigitte Keller-Stanislawski
PURPOSE: We aimed at investigating whether, in Germany, the number of individual case safety reports (ICSR) of confirmed narcolepsy following Pandemrix® vaccination notified to the Paul-Ehrlich-Institut (PEI, German Federal Institute for Vaccines and Biomedicines) was higher than expected when compared with the prepandemic background incidence rates. METHODS: ICSR of narcolepsy after vaccination with Pandemrix® notified to the PEI until September 2016 were reviewed and validated according to the criteria of narcolepsy defined by the Brighton Collaboration (BC)...
August 14, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28807338/molecular-pathology-diagnosis-of-diffuse-large-b-cell-lymphoma-using-biomed-2-clonal-gene-rearrangements
#7
Saeid Ghorbian
BACKGROUND: Clonality testing for immunoglobulin gene rearrangement analysis could be implemented effectively as a useful technique for conventional diagnosis of lymphoma. The European Biomedicine and Health Concerted Action Project BMH4-CT98-3936 (BIOMED-2) have been suggested a gold standard method to clonality detection. OBJECTIVES: We tested empirically clonality rearrangements of IGH and incomplete IGH D-J, on formalin-fixed, paraffin embedded (FFPE) tissue of patients with diffuse large B cell lymphoma (DLBCL)...
August 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28805368/pyrophosphate-recognition-and-sensing-in-water-using-bis-zinc-ii-dipicolylamino-functionalized-peptides
#8
Katrina A Jolliffe
Phosphate oxoanions and phosphorylated biomolecules (such as nucleotides, lipids, and proteins) play key roles in a wide range of biological processes. The ability to selectively detect these ions in the presence of each other has numerous applications in biochemistry and biomedicine. However, receptors and sensors that can discriminate between polyphosphate species with high selectivity and in biologically relevant conditions are rare. In this Account, we show how peptides (both cyclic and linear) can be used to position two zinc(II)dipicolylamine [Zn(II)DPA] binding sites in an appropriate arrangement to provide selective binding of pyrophosphate (PPi) in the presence of other polyphosphate species, including ATP, and in complex media such as cell growth buffer...
August 14, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28803469/chiral-ceramic-nanoparticles-of-tungsten-oxide-and-peptide-catalysis
#9
Shuang Jiang, Mahshid Chekini, Zhi-Bei Qu, Yichun Wang, Aydan Yeltik, Yuangang Liu, Alex Kotlyar, Tianyong Zhang, Bin Li, Hilmi Volkan Demir, Nicholas A Kotov
The chirality of nanoparticles (NPs) and their assemblies has been investigated predominantly for noble metals and II-VI semiconductors. However, ceramic NPs represent the majority of nanoscale materials in Nature. The robustness and other innate properties of ceramics offer technological opportunities in catalysis, biomedical sciences, and optics. Here we report the preparation of chiral ceramic NPs, as represented by tungsten oxide hydrate, WO3-x·H2O, dispersed in ethanol. The chirality of the metal oxide core, with an average size of ca 1...
August 12, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28799737/method-to-assemble-genomic-dna-fragments-or-genes-on-human-artificial-chromosome-with-regulated-kinetochore-using-a-multi-integrase-system
#10
Nicholas C O Lee, Jung-Hyun Kim, Nikolai Petrov, Hee-Sheung Lee, Hiroshi Masumoto, William C Earnshaw, Vladimir Larionov, Natalay Kouprina
The production of cells capable of carrying multiple transgenes to Mb-size genomic loci has multiple applications in biomedicine and biotechnology. In order to achieve this goal, three key steps are required: i) Cloning of large genomic segments; ii) Insertion of multiple DNA blocks at a precise location and iii) The capability to eliminate the assembled region from cells. In this study, we designed the Iterative Integration System (IIS) that utilizes recombinases Cre, ΦC31 and ΦBT1, and combined it with Human Artificial Chromosome (HAC) possessing a regulated kinetochore (alphoid(tetO)-HAC)...
August 11, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28795530/construction-of-silica-based-micro-nanoplatforms-for-ultrasound-theranostic-biomedicine
#11
REVIEW
Yang Zhou, Xiaoxia Han, Xiangxiang Jing, Yu Chen
Ultrasound (US)-based biomedicine has been extensively explored for its applications in both diagnostic imaging and disease therapy. The fast development of theranostic nanomedicine significantly promotes the development of US-based biomedicine. This progress report summarizes and discusses the recent developments of rational design and fabrication of silica-based micro/nanoparticles for versatile US-based biomedical applications. The synthetic strategies and surface-engineering approaches of silica-based micro/nanoparticles are initially discussed, followed by detailed introduction on their US-based theranostic applications...
August 10, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28793809/-these-people-who-dig-roots-in-the-forests-cannot-treat-hiv-women-and-men-in-durban-south-africa-reflect-on-traditional-medicine-and-antiretroviral-drugs
#12
Amy Weintraub, Joanne E Mantell, Kelsey Holt, Renée A Street, Catriona Wilkey, Suraya Dawad, Tsitsi B Masvawure, Susie Hoffman
Relatively few empirical investigations of the intersection of HIV biomedical and traditional medicine have been undertaken. As part of preliminary work for a longitudinal study investigating health-seeking behaviours among newly diagnosed individuals living with HIV, we conducted semi-structured interviews with 24 urban South Africans presenting for HIV testing or newly enrolled in HIV care; here we explored participants' views on African traditional medicine (TM) and biomedical HIV treatment. Notions of acceptance/non-acceptance were more nuanced than dichotomous, with participants expressing views ranging from favourable to reproachful, often referring to stories they had heard from others rather than drawing from personal experience...
August 10, 2017: Global Public Health
https://www.readbyqxmd.com/read/28782892/surfaces-inspired-by-the-nepenthes-peristome-for-unidirectional-liquid-transport
#13
REVIEW
Pengfei Zhang, Liwen Zhang, Huawei Chen, Zhichao Dong, Deyuan Zhang
The slippery peristome of the pitcher plant Nepenthes has attracted much attention due to its unique function for preying on insects. Recent findings on the peristome surface of Nepenthes alata demonstrate a fast and continuous unidirectional liquid transport, which is enabled by the combination of a pinning effect at the sharp edges and a capillary rise in the wedge, deriving from the multiscale structure, which provides inspiration for designing and fabricating functional surfaces for unidirectional liquid transport...
August 7, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28781813/association-between-polymorphisms-in-folate-metabolism-genes-and-maternal-risk-for-down-syndrome-a-meta-analysis
#14
Yanqing Gu
Previous studies have focused on the association between polymorphisms of the genes involved in folate metabolism and Down syndrome (DS); however, the results remain inconclusive. The present meta-analysis was conducted to assess the association between RFC-1 A80G/MTR A2756G/CBS 844ins68 polymorphisms and the maternal risk of DS. Published studies were retrieved from PubMed, Embase, China National Knowledge Infrastructure and Chinese Biomedicine databases. Pooled odds ratios (ORs) with 95% confidence interval (CIs) were calculated using the fixed- or random-effects model...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28777502/carbon-nanomaterials-in-biological-studies-and-biomedicine
#15
REVIEW
Nagappa L Teradal, Raz Jelinek
The "carbon nano-world" has made over the past few decades huge contributions in diverse scientific disciplines and technological advances. While dramatic advances have been widely publicized in using carbon nanomaterials such as fullerenes, carbon nanotubes, and graphene in materials sciences, nano-electronics, and photonics, their contributions to biology and biomedicine have been noteworthy as well. This Review focuses on the use of carbon nanotubes (CNTs), graphene, and carbon quantum dots [encompassing graphene quantum dots (GQDs) and carbon dots (C-dots)] in biologically oriented materials and applications...
August 4, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28776985/amphiphile-mediated-ultrasmall-aggregation-induced-emission-dots-for-ultrasensitive-fluorescence-biosensing
#16
Haiyin Li, Chuanfeng Wang, Ting Hou, Feng Li
The development of ultrasensitive and highly selective fluorescence biosensors for diverse analytes is highly desirable but remains a challenge. It is attributable to the scarcity of fluorogens with promising brightness, stability, and nontoxicity, which primarily determine the performance of fluorescence biosensors. Herein, we report the design and preparation of aggregation induced emission (AIE) dots with high brightness, exceptional colloidal stability, ultrasmall size, and functional groups for developing ultrasensitive biosensor through the electrostatic conjugation to biological molecules, and use blemycin (BLM) as the proof-of-concept analyte...
August 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28776980/amphiphilic-peptide-self-assembly-expansion-to-hybrid-materials
#17
Viktoria Mikhalevich, Ioana Craciun, Myrto Kyropoulou, Cornelia G Palivan, Wolfgang P Meier
The design of functional systems with sizes in the nanometer range is a key challenge in fields such as biomedicine, nanotechnology or engineering. Some of the most promising materials nowadays consist of self-assembling peptides or peptide-polymer hybrid materials because of the versatility, and the resulting properties, which can be achieved with these structures. Self-assembly of pure amphiphilic peptides or in combination with block copolymers results in a large variety of nanostructures (micelles, nanoparticles (NPs), compartments, planar membranes) each with different characteristics and tunable properties...
August 4, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28776867/pain-and-dualism-which-dualism
#18
Elisa Arnaudo
In the literature, the allegation to pursue approaches grounded on Cartesian dualism in medicine is widespread. In this paper, I argue that dualism informing biomedicine has not only to do with a Cartesian view of mind and body, but that multiple dualisms are at play in biomedical approach to disease, especially regarding complex pain conditions. A form of epistemological dualism entailing the primacy of the physician's model of knowledge on the patient's direct experience of suffering is pointed out as the source of the inadequate medical attitude towards pain, particularly in relation to its complex forms such as fibromyalgic syndrome...
August 4, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28773936/preparation-and-characterization-of-chitosan-agarose-composite-films
#19
Zhang Hu, Pengzhi Hong, Mingneng Liao, Songzhi Kong, Na Huang, Chunyan Ou, Sidong Li
Nowadays, there is a growing interest to develop biodegradable functional composite materials for food packaging and biomedicine applications from renewable sources. Some composite films were prepared by the casting method using chitosan (CS) and agarose (AG) in different mass ratios. The composite films were analyzed for physical-chemical-mechanical properties including tensile strength (TS), elongation-at-break (EB), water vapor transmission rate (WVTR), swelling ratio, Fourier-transform infrared spectroscopy, and morphology observations...
September 30, 2016: Materials
https://www.readbyqxmd.com/read/28772027/escherichia-coli-surface-display-for-the-selection-of-nanobodies
#20
REVIEW
Valencio Salema, Luis Ángel Fernández
Nanobodies (Nbs) are the smallest functional antibody fragments known in nature and have multiple applications in biomedicine or environmental monitoring. Nbs are derived from the variable segment of camelid heavy chain-only antibodies, known as VHH. For selection, libraries of VHH gene segments from naïve, immunized animals or of synthetic origin have been traditionally cloned in E. coli phage display or yeast display systems, and clones binding the target antigen recovered, usually from plastic surfaces with the immobilized antigen (phage display) or using fluorescence-activated cell sorting (FACS; yeast display)...
August 3, 2017: Microbial Biotechnology
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