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Elizabeth McDonald, Raymond Teets, Caroline Ortiz, Christine Gilchrist, Eve Waltermaurer, Elidania Perez, Benjamin Kligler
INTRODUCTION: Irritable bowel syndrome (IBS) is a chronic debilitating functional gastrointestinal disorder that affects a large proportion of the general population. Dietary and mind-body approaches have shown some effectiveness in reducing IBS symptoms. OBJECTIVES: The purpose of this project was to test the feasibility of a low cost, group-oriented integrative medicine approach to IBS, and to explore whether such an approach improves participant outcomes. METHODS: This was a randomized-controlled trial involving a 4-week group-oriented treatment intervention combining dietary intervention and mind-body therapies followed by 8-weeks of telephonic health coaching...
July 20, 2018: Explore: the Journal of Science and Healing
Yongchuang Liu, Tiantian Li, Ruixue Zhang, Lina Guo, Kun Liu
This study aims to investigate a moderated mediation model in the relationship between poor sleep quality, depressive symptoms, perceived stress, sense of coherence. A cross-sectional survey was conducted from May to July 2015 in Liaoning Province, China. 1050 community residents aged ≥60 years were ultimately chosen to participate. The Chinese version of the Pittsburgh Sleep Quality Index (CPSQI), the Epidemiological Studies Depression Scale(CES-D),the Chinese version Perceived Stress Scale(CPSS), and the Sense of Coherence Scale (SOC) were used to estimate sleep quality, late-life depression, perceived stress, and sense of coherence (SOC) respectively...
September 12, 2018: Archives of Gerontology and Geriatrics
Daiki Takekawa, Takashi Kudo, Junichi Saito, Futoshi Kimura, Yoshikazu Nikaido, Kaori Sawada, Norio Yasui-Furukori, Kazuyoshi Hirota
BACKGROUND: Depression is a seriously disabling public health problem with very high world-wide prevalence. This study examined cross-sectional association between depression and both inflammatory markers and laboratory data involved in metabolic disturbance among Japanese subjects. METHODS: This cross-sectional study is a secondly analysis for the data of the Iwaki Health Promotion Project 2014 (1167 subjects). Plasma inflammatory markers and laboratory metabolic data involved were used...
September 11, 2018: Journal of Affective Disorders
Elizabeth C George, Raffaella Bucciardini, Laura Richert, Nikos Dedes, Vincenzo Fragola, Pythia Nieuwkerk, Bruno Spire, Alain Volny-Anne, Brian West, Jean-Michel Molina, Andrzej Horban, Julie Fox, Anton Pozniak, Stefano Vella, Monique Termote, François Raffi
BACKGROUND: There are few data comparing patient reported outcomes (PROs) in randomized trials of initial antiretroviral therapy (ART). We present results from a substudy of the NEAT001/ANRS143 trial. METHODS: The randomized trial compared first-line DRV/r 800/100mg once daily plus RAL 400mg twice daily and DRV/r plus TDF/FTC 245/200mg once daily. Changes in PROs were assessed with 3 questionnaires: EuroQoL 5 domains (EQ-5D), Centre for Epidemiologic Studies Depression scale (CES-D), and HIV Treatment Satisfaction (HIVTSQ)...
September 3, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Gabi Aisenberg Romano, Inbar Fried Zaig, Anat Halevy, Foad Azem, Ami Amit, Miki Bloch
To explore the mood protective effect of prophylactic SSRI treatment on women undergoing IVF suffering from moderate affective and anxiety symptoms. In a randomized double blind, placebo-controlled, parallel design study, 41 women diagnosed with an Adjustment Disorder, who were undergoing IVF treatments, were randomized into two groups; a study group (n = 22) administered escitalopram 10 mg/day, and a control group (n = 19) administered placebo for a total of 8 weeks before and during the IVF treatment cycle...
September 17, 2018: Archives of Women's Mental Health
Rui C Campos, Ronald R Holden, Margarida Gomes
Several studies have consistently related psychological pain to suicide risk. Psychache, according to Shneidman's perspective and measured by the Psychache Scale has been confirmed as an important variable in risk prediction. In the present study, we evaluated psychache as a construct related to suicide risk using data obtained with the Portuguese version of the Psychache Scale translated from the original English version. A community sample of 628 individuals responded to the Portuguese version of the Psychache Scale, the Suicidal Behavior Questionnaire-Revised, the CES-D Scale, the Beck Hopelessness Scale, and the Suicide Ideation Questionnaire...
September 14, 2018: Death Studies
Qin Zhou, Tianyu Wang, Kisalaya Basu
The association between body size and mental health has been the focus of many studies. Results, however, varies between studies. This study aimed to investigate the association between BMI and depressive symptoms among Chinese adults. We also further explored childhood starvation as a potential mediator of this association. The China Health and Retirement Longitudinal Study data, a representative national survey of adults age 45 and older was used in this study. Results showed that the prevalence of overweight and obesity were 28...
August 31, 2018: Psychiatry Research
Martin Griebe, Anne Ebert, Frauke Nees, Katharina Katic, Benjamin Gerber, Kristina Szabo
INTRODUCTION: Stress-related transient inhibition of memory formation in the hippocampus has been hypothesized as one of the underlying pathomechanisms of transient global amnesia (TGA). TGA episodes, during which patients cannot encode and recall new information (anterograde amnesia affecting episodic long-term memory), are frequently preceded by a psychologically or physically stressful event. METHODS: We measured salivary cortisol during acute TGA in 14 patients, as well as cortisol day-profiles and the effect of experimental exposure to stress (using the socially evaluated cold pressor test) on cortisol levels during the subacute phase...
August 25, 2018: Psychoneuroendocrinology
Peter Glick, Jill Luoto, Mark S Orrs, Matthew S Oliva, Geoffrey C Tabin, David S Sanders, Benjamin J Thomas, Sanduk Ruit, Tefera Belachew, Alemu Kerie Tasfaw
PURPOSE: To comprehensively measure the impacts of cataract surgery on patients' activities and mental and physical health, caregivers' well-being, and household incomes in a resource-poor setting Methods: One thousand two hundred thirty-four bilaterally blind older adults in Amhara region, Ethiopia, were interviewed at baseline and 1030 (83%) re-interviewed at follow-up 1 year later. Six hundred ninety three (45%) at baseline were diagnosed with cataracts and offered free surgery, of which 484 (73%) were operated...
September 7, 2018: Ophthalmic Epidemiology
Lydia Poole, Andrew Steptoe
OBJECTIVE: To assess the association between depressive symptoms and incident chronic illness burden in prospective longitudinal analyses. METHODS: We analysed data from 2472 participants (62.88 ± 8.49 years old; 50.8% female) from the English Longitudinal Study of Ageing (ELSA). Depressive symptoms were measured using the Centre for Epidemiological Studies Depression (CES-D) scale at baseline in 2004, and participants were followed up for 10 years. Participants with prevalent illness at baseline (coronary heart disease [CHD], other cardiac illness, stroke, cancer, diabetes/high blood glucose, arthritis, lung disease, osteoporosis and Parkinson's disease) were excluded from models predicting illness burden (the sum of illnesses reported) over follow-up...
October 2018: Journal of Psychosomatic Research
Peng Ouyang, Wenjun Sun
BACKGROUND: Depressive symptoms are a worldwide health problem. However, the research about the effect of depressive symptoms on the fall among the Chinese mid-aged and elderly people is lacking. Therefore, this study aims to investigate the association between depressive symptoms and fall accidents among middle-aged and elderly people in China. METHODS: This study was conducted based on 12,527 sets of data from China Health and Retirement Longitudinal Survey (CHARLS)...
September 5, 2018: Environmental Health and Preventive Medicine
Jun Ick Jung, Jun Seok Son, Young Ouk Kim, Chang Ho Chae, Chan Woo Kim, Hyoung Ouk Park, Jun Ho Lee, Young Hoo Shin, Jea Chul Ha
Background: Since the 1980s, restructuring, which includes downsizing, closures, mergers, and privatization, has expanded worldwide, and various studies have investigated its effect on health. However, previous studies have mainly focused on restructuring accompanied by massive lay-offs, and the effect of a merger on workers' health is still controversial. This study aims to investigate changes in worker depression and job stress after a merger without downsizing, which is unusual in Korea...
2018: Annals of Occupational and Environmental Medicine
Dilys Lam, Marie-Laure Ancelin, Karen Ritchie, Rosanne Freak-Poli, Richard Saffery, Joanne Ryan
BACKGROUND: Disrupted serotonergic signaling is often a feature of depression and the role of the serotonin transporter gene (SLC6A4), responsible for serotonin re-uptake, has received much attention in this regard. Most studies have focused on the polymorphic 5-HTTLPR upstream repeat, or DNA methylation at the promoter CpG island. Few studies have explored the influence of genetic variation across the gene on DNA methylation, and their combined association with depression risk. The aim of this study was to determine whether genetic variation in the SLC6A4 gene influences promoter DNA methylation, and whether these are associated with depression status...
September 4, 2018: BMC Psychiatry
Cielito C Reyes, Karen O Anderson, Carmen E Gonzalez, Haley Candra Ochs, Monica Wattana, Gyanendra Acharya, Knox H Todd
OBJECTIVES: Pain and depression frequently co-occur in patients with cancer. Although pain is a common reason for emergency department (ED) presentation by these patients, depression frequently goes unrecognised during an ED visit. In this study, we assessed the risk for depression in patients with cancer presenting to the ED for uncontrolled pain and assessed the extent to which the risk for depression was associated with survival in this population. METHODS: Participants were consecutive patients with cancer taking Schedule II opioids (n=209) who presented to the ED of a tertiary cancer centre for uncontrolled pain...
August 31, 2018: BMJ Supportive & Palliative Care
Konstantinos N Fountoulakis, Vangelis Karavelas, Stefania Moysidou, Dimitris Mavridis, Konstantinos Pastiadis, Nicole Petalidou, Ioannis Nimatoudis, Siegfried Kasper
INTRODUCTION: This study tests the efficacy of pregabalin versus placebo as adjunctive treatment in patients with generalized anxiety disorder (GAD) comorbid with unipolar major depression (UMD) and with an early nonresponse to escitalopram. METHODS: This is a double-blind, placebo-controlled 8-week add-on study of pregabalin, 75-600 mg/day (n=31) versus placebo (n=29) on open-label escitalopram in outpatients meeting the DSM-IV-TR criteria for GAD and UMD. The main outcome measures were change from baseline to endpoint in total STAI-S, Trail-Making Test B (TMT-B) and the Center of Epidemiological Studies Depression Scale (CES-D)...
August 31, 2018: Pharmacopsychiatry
Jonathan M Konel, Fatima Warsame, Hao Ying, Christine E Haugen, Alexandra Mountford, Nadia M Chu, Deidra C Crews, Niraj M Desai, Jacqueline M Garonzik-Wang, Jeremy D Walston, Silas P Norman, Dorry L Segev, Mara A McAdams-DeMarco
Depressive symptoms and frailty are each independently associated with morbidity and mortality in kidney transplant (KT) recipients. We hypothesized that having both depressive symptoms and frailty would be synergistic and worse than the independent effect of each. In a multi-center cohort study of 773 KT recipients, we measured the Fried frailty phenotype and the modified 18-question Center for Epidemiologic Studies-Depression Scale (CES-D). Using adjusted Poisson regression and survival analysis, we tested whether depressive symptoms (CES-D score>14) and frailty were associated with KT length of stay (LOS), death-censored graft failure (DCGF), and mortality...
August 27, 2018: Clinical Transplantation
Adrienne Kegye, Szabolcs Takács, Borbála Ries, Ágnes Zana, Katalin Hegedűs
INTRODUCTION: The Professional Quality of Life Scale, measuring the quality of professional life, has been developed to examine the positive and negative changes in the work of those who have undergone extremely stressful experiences. The quality of life of the personnel of palliative-hospice teams may be influenced physically as well as emotionally by their every-day experiences of suffering, death, dying and the patients' traumas. AIM: The aim of the study was the examination of the psychometric features and factor structure of the Hungarian version of the Professional Quality of Life Scale questionnaire, which can measure compassion fatigue and satisfaction, secondary traumatisation and burnout...
September 2018: Orvosi Hetilap
Kyu-Man Han, Young-Hoon Ko, Ho-Kyoung Yoon, Changsu Han, Byung-Joo Ham, Yong-Ku Kim
BACKGROUND: We investigated the interactive effects of depressive symptoms and chronic diseases on health care utilization among elderly people and explored the potential moderating effect of gender and the mediating effect of self-rated health (SRH) on the association between depressive symptoms and health care utilization. METHOD: We analyzed data from 5223 people aged 60 years or older living in the community from the Korea Welfare Panel Study in 2015. Depressive symptoms were measured using an 11-item version of the Center for Epidemiologic Studies Depression (CES-D-11) Scale and morbidity within 28 disease categories was assessed...
December 1, 2018: Journal of Affective Disorders
Sibo Zhao, Guo Yiyue
The aim of this study is to examine the mediating role of family function on the association between mother's education and their offspring's depression in college (M age = 19.19, SD = 1.60). A sample of 1177 student respondents was systematically sampled from 12 universities that include both generalist universities and specialist institutions in Beijing. The Family Assessment Device (FAD) and Center for Epidemiologic Studies Depression Scale (CES-D) were used to measure family function and students' depression level, respectively...
August 15, 2018: Psychiatry Research
Snehal N Shah, Alan Fossa, Abigail S Steiner, John Kane, Jonathan I Levy, Gary Adamkiewicz, Willie Mae Bennett-Fripp, Margaret Reid
Housing quality, which includes structural and environmental risks, has been associated with multiple physical health outcomes including injury and asthma. Cockroach and mouse infestations can be prime manifestations of diminished housing quality. While the respiratory health effects of pest infestation are well documented, little is known about the association between infestation and mental health outcomes. To address this gap in knowledge and given the potential to intervene to reduce pest infestation, we assessed the association between household pest infestation and symptoms of depression among public housing residents...
August 23, 2018: Journal of Urban Health: Bulletin of the New York Academy of Medicine
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