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Barbara Hanratty, Daniel Stow, Danni Collingridge Moore, Nicole K Valtorta, Fiona Matthews
Background: loneliness has an adverse effect on health and well-being, and is common at older ages. Evidence that it is a risk factor for care home admission is sparse. Objective: to investigate the association between loneliness and care home admission. Setting: English Longitudinal Study of Ageing (ELSA). Participants: two-hundred fifty-four individuals across seven waves (2002-15) of ELSA who moved into care homes were age, sex matched to four randomly selected individuals who remained in the community...
July 10, 2018: Age and Ageing
Susan A Everson-Rose, Cari J Clark, Qi Wang, Hongfei Guo, Peter Mancuso, Howard M Kravitz, Joyce T Bromberger
Small clinical studies suggest depression is associated with alterations in adiponectin and leptin, adipocyte-derived secretory proteins involved in metabolic regulation; however, longitudinal data on these association are lacking. This study examined cross-sectional and longitudinal associations of depressive symptoms and major depressive disorder (MDD) with adiponectin and leptin in healthy middle-aged women (mean (SD) age, 45.6 (2.5) years). Cross-sectional analyses included 575 women with baseline adipokine data; longitudinal analyses included 262 women with 2-4 adipokine measurements over 5 years...
July 5, 2018: Psychoneuroendocrinology
Masumi Ishihara, Tami Saito, Takashi Sakurai, Hiroyuki Shimada, Hidenori Arai
Safer and more effective programs are required to cope with an increasing number of older people with depression. Hence, we developed the Positive Photo Appreciation (PPA) program. A three-month pilot randomized controlled trial was conducted with healthy Japanese individuals aged 65⁻84 years, assigned to a PPA group ( n = 28) or Photo Correspondence Education (PCE) (control group) ( n = 27). We used the Center for Epidemiologic Studies Depression Scale (CES-D) score as the primary outcome measure. Secondary outcome measures, among others, were cognitive function and positive emotion...
July 12, 2018: International Journal of Environmental Research and Public Health
Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Shaheen Majeed, Furqan Ali
Background: The modification of microbial ecology in human gut by supplementing probiotics may be an alternative strategy to ameliorate or prevent depression. Objective: The current study was conducted to assess the safety and efficacy of the probiotic strain Bacillus coagulans MTCC 5856 for major depressive disorder (MDD) in IBS patients. Method: Patients ( n = 40) diagnosed for MDD with IBS were randomized (1:1) to receive placebo or B. coagulans MTCC 5856 at a daily dose of 2 × 109 cfu (2 billion spores) and were maintained to the end of double-blind treatment (90 days)...
2018: Food & Nutrition Research
Yoshihiro Miyake, Keiko Tanaka, Masashi Arakawa
ITIH3 and ITIH4 are involved in the stabilization of the extracellular matrix. Several genome-wide association studies and case-control studies regarding psychiatric disorders have identified ITIH3 and ITIH4 single nucleotide polymorphisms (SNPs). The present case-control study examined the relationship between ITIH3 SNPs rs2535629 and rs736408 and ITIH4 SNPs rs3821831 and rs2239547 and depressive symptoms during pregnancy in Japan. Cases comprised 273 women with depressive symptoms during pregnancy defined as a Center for Epidemiological Studies Depression Scale (CES-D) score ≥ 16...
July 10, 2018: Journal of Neural Transmission
Gregory J Tranah, Jeanne E Maglione, Kristine Yaffe, Shana M Katzman, Todd M Manini, Stephen Kritchevsky, Anne B Newman, Tamara B Harris, Steven R Cummings
OBJECTIVES: Mitochondrial DNA (mtDNA) heteroplasmy is a mixture of normal and mutated mtDNA molecules in a cell. High levels of heteroplasmy at several mtDNA sites in complex I lead to inherited neurological neurologic diseases and brain magnetic resonance imaging (MRI) abnormalities. Here, we test the hypothesis that mtDNA heteroplasmy at these complex I sites is associated with depressive symptoms in the elderly. METHODS: We examined platelet mtDNA heteroplasmy for associations with depressive symptoms among 137 participants over age 70 from the community-based Health, Aging and Body Composition Study...
July 8, 2018: International Journal of Geriatric Psychiatry
Irina Lazarevich, Maria Esther Irigoyen Camacho, María Consuelo Velázquez-Alva, Norma Lara Flores, Oralia Nájera Medina, Marco A Zepeda Zepeda
INTRODUCTION: depression is frequently accompanied by overeating and a preference for certain foods that may consequently lead to weight gain. OBJECTIVES: a) to determine the prevalence of depression and the consumption of unhealthy food in first-year college students; and b) to analyze the association between depression score and food consumption frequency. METHODS: a cross-sectional study was carried out in 1,104 freshman students, 40.3% men and 59...
May 10, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Antonios A Mougias, Foteini Christidi, Evaggelia Kontogianni, Elena Skaltsounaki, Anastasios Politis, Antonios Politis
Background: Informant-based rating scales are widely used in dementia but patients' and caregivers' features influence the final scoring. We aimed to evaluate the role of patient- and caregiver-related factors in a caregiver rated Global Deterioration Scale (GDS) score in a sample of Greek patients with dementia. Methods: We included 194 patients with dementia and 194 caregivers/family relatives; Mini-Mental State Examination (MMSE); Neuropsychiatric Inventory (NPI); Katz Index of Activities of Daily Living (K-IADL) were administered to (a) patients and Center for Epidemiologic Studies-Depression (CES-D) Scale; Zarit Burden Interview (ZBI) to (b) caregivers...
2018: Current Gerontology and Geriatrics Research
Cillian P Mc Dowell, Angela Carlin, Laura Capranica, Christina Dillon, Janas M Harrington, Jeroen Lakerveld, Anne Loyen, Fiona Chun Man Ling, Johannes Brug, Ciaran MacDonncha, Matthew P Herring
BACKGROUND: Depression is a prevalent, debilitating, and often recurrent mood disorder for which successful first-line treatments remains limited. The purpose of this study was to investigate the cross-sectional associations between self-reported physical activity (PA) and depressive symptoms and status among Irish adults, using two existing datasets, The Irish Longitudinal Study on Ageing (TILDA) and The Mitchelstown Cohort Study. METHODS: The two selected databases were pooled (n = 10,122), and relevant variables were harmonized...
July 1, 2018: BMC Public Health
Andre F Carvalho, Brendon Stubbs, Michael Maes, Marco Solmi, Davy Vancampfort, Paul A Kurdyak, Andre R Brunoni, Muhammad I Husain, Ai Koyanagi
BACKGROUND: The associations of different patterns of alcohol consumption and the incidence and persistence of depressive and anxiety symptoms in older age remain unclear. METHODS: Data on 6095 adults aged ≥ 50 years old from the Irish Longitudinal Study on Aging (TILDA) was analyzed. Participants completed the CAGE instrument to screen for problematic alcohol use at baseline between October 2009 and February 2011. Outcomes were incident (assessed by the CES-D scale) and anxiety (assessed by the Hospital Anxiety and Depressive scale) symptoms after a two-year follow-up as well as persistence of probable depression and anxiety among those with a positive screen for those disorders at baseline...
June 19, 2018: Journal of Affective Disorders
Jihyung Hong
This study examined the relationship among mental health, perceived discrimination and ethnic identity among Korean Chinese (Joseonjok) who have return-migrated to South Korea. A survey was conducted with 399 Joseonjok adults (≥ 19 years) residing in the capital city Seoul or nearby. Depression was measured using the (self-report) Center for Epidemiologic Studies Depression Scale-Korean (CES-D-K) version (n = 292, mean age = 42.6, female = 56.5%). Perceived discrimination and ethnic identity were assessed with single-item questions...
June 28, 2018: Journal of Immigrant and Minority Health
Aleksandra Kroemeke, Ewelina Kubicka
BACKGROUND: Perceived social support relates to infertility-related distress in couples undergoing assisted reproductive technology (ART) treatment. Studies examining the effect of other support types on both positive and negative adjustment among infertile couples are scarce or non-existent. Therefore, this study investigated the effects of support receipt, provision, invisibility (the discrepancy between one partner's received and the other partner's provided support), and equity (the discrepancy between each partner's received and provided support) on the positive (life purpose) and negative (depressive symptoms) indices of well-being in couples undergoing ART treatment...
2018: PloS One
Rebecca Dwommoh, Katherine Sorsdahl, Bronwyn Myers, Kwaku Poku Asante, Tracey Naledi, Dan J Stein, Susan Cleary
Background: There are limited data describing the cost-effectiveness of brief interventions for substance use in resource-poor settings. Using a patient and provider perspective, this study investigates the cost-effectiveness of a brief motivational interviewing (MI) intervention versus a combined intervention of MI and problem solving therapy (MI-PST) for reducing substance use among patients presenting to emergency departments, in comparison to a control group. Methods: Effectiveness data were extracted from Project STRIVE (Substance use and Trauma InterVention) conducted in South Africa...
2018: Cost Effectiveness and Resource Allocation: C/E
Yijun Bao, Lizhuo Li, Yanlei Guan, Yan Liu, Wei Wang, Dan Zhao, Shanwei Tao, Yuhui Ling, Yan Wang, Bo Bi, Anhua Wu, Liu Cao
BACKGROUND: It is common for central nervous system (CNS) tumor patients to suffer from depressive symptoms. If unrecognized or untreated, CNS tumors may lead to many serious problems in these patients. This study examines the association of social support with depressive symptoms in CNS tumor patients and explores the extent to which hope mediates this relationship. METHODS: A total of 269 CNS tumor patients in China were included in this study. We assessed depressive symptoms using the Epidemiologic Studies Depression Scale (CES-D), social support using the Perceived Social Support Scale (PSSS), and hope using the Herth Hope Index (HHI)...
June 25, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Yan Guo, Y Alicia Hong, Jiaying Qiao, Zhimeng Xu, Hanxi Zhang, Chengbo Zeng, Weiping Cai, Linghua Li, Cong Liu, Yiran Li, Mengting Zhu, Nathan Asher Harris, Cui Yang
BACKGROUND: People living with HIV (PLWH) suffer from high rates of mental illness; but targeted effective interventions are limited, especially in developing countries. High penetration of smartphone usage and widespread acceptance of social media applications provide an unprecedented opportunity for mobile-based health interventions (mHealth interventions) in resource-limited settings like China. The current report describes the design and sample characteristics of the Run4Love randomized controlled trial (RCT) aimed at improving mental health in PLWH in China...
June 26, 2018: BMC Public Health
Moufidath Adjibade, Cédric Lemogne, Chantal Julia, Serge Hercberg, Pilar Galan, Karen E Assmann, Emmanuelle Kesse-Guyot
BACKGROUND: Several modifiable lifestyle indicators, including diet, smoking, alcohol consumption, weight and physical activity have been associated with depression; however, their combined effect has been less studied. The aim of this study was to calculate a Healthy Lifestyle Index (HLI) composed of the 5 above-mentioned indicators and investigate its association with incident depressive symptoms. METHODS: The study sample consisted of 25,837 participants from the NutriNet-Santé study, initially free of depressive symptoms...
June 15, 2018: Journal of Affective Disorders
Mandakh Bekhbat, C Christina Mehta, Sean D Kelly, Aimee Vester, Ighovwerha Ofotokun, Jennifer Felger, Gina Wingood, Kathryn Anastos, Deborah R Gustafson, Seble Kassaye, Joel Milam, Bradley Aouizerat, Kathleen Weber, Elizabeth T Golub, Michelle Floris Moore, Ralph Diclemente, Margaret Fischl, Mirjam-Colette Kempf, Pauline Maki, Gretchen N Neigh
Chronic inflammation caused by HIV infection may lead to deficient glucocorticoid (GC) signaling predisposing people living with HIV to depression and other psychiatric disorders linked to GC resistance. We hypothesized that comorbid HIV and depressive symptoms in women would synergistically associate with deficits in GC signaling. This cross-sectional study used samples obtained from the Women's Interagency HIV Study (WIHS). The Centers for Epidemiological Studies (CES-D) was used to define depression in four groups of women from the Women's Interagency HIV Study (WIHS): 1) HIV-negative, non-depressed (n = 37); 2) HIV-negative, depressed (n = 34); 3) HIV-positive, non-depressed (n = 38); and 4) HIV-positive, depressed (n = 38)...
June 18, 2018: Psychoneuroendocrinology
Taiki Kambe, Asako Yasuda, Setsuo Kinoshita, Masahiro Shigeta, Toru Kinoshita
Background/Aims: Depression and cognitive decline are reported to be interrelated. Depression of older adults with memory complaints who seek medical help have not been well documented. This study was carried out to test the hypothesis that a relatively high level of depressive symptoms associated with brain structure is characteristic of people who visited a memory clinic unaccompanied (UA). Method: We retrospectively compared Center for Epidemiologic Studies Depression Scale (CES-D, for evaluation of depressive symptoms) scores of UA subjects ( n = 21) with those of people who were accompanied ( n = 75)...
May 2018: Dementia and Geriatric Cognitive Disorders Extra
Hossam A Shaltout, Sung W Lee, Catherine L Tegeler, Joshua R Hirsch, Sean L Simpson, Lee Gerdes, Charles H Tegeler
Background: Heart rate variability (HRV) is an indicator of dynamic adaptability of the autonomic nervous system. Few interventions target upstream, cerebral cortex components of the heart-brain system for autonomic management. We report changes in HRV and baroreflex sensitivity (BRS), associated with use of a noninvasive, closed-loop, allostatic, computer-guided, acoustic stimulation neurotechnology. Methods: Over 5 years, 220 subjects with heterogeneous neurological, cardiovascular, and psychophysiological conditions consecutively enrolled in a naturalistic, single-arm study exploring clinical effects associated with use of the neurotechnology...
2018: Frontiers in Public Health
Kiona Krueger Weisel, Dirk Lehr, Elena Heber, Anna-Carlotta Zarski, Matthias Berking, Heleen Riper, David Daniel Ebert
BACKGROUND: Although internet-based and mobile-based stress management interventions (iSMIs) may be a promising strategy to reach employees suffering from high chronic stress, it remains unknown whether participants with high symptom severity of depression or anxiety also benefit from iSMIs or should be excluded. OBJECTIVE: This study aimed to evaluate the efficacy of iSMIs in subgroups with high symptom severity and to test whether baseline symptom severity moderates treatment outcome...
June 19, 2018: Journal of Medical Internet Research
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