keyword
MENU ▼
Read by QxMD icon Read
search

Primary hyperparathyroidism

keyword
https://www.readbyqxmd.com/read/29778311/a-rare-cause-of-primary-hyperparathyroidism-parathyroid-lipoadenoma
#1
Sabri Özden, Servet Güreşci, Barış Saylam, Gül Dağlar
OBJECTIVE: The main cause of primary hyperparathyroidism is a single parathyroid adenoma. Parathyroid lipoadenomas contain abundance of fat cells. Because of these histological features, they can mimic normal parathyroid tissue at the histopathologic examination and radiological imaging could be difficult to localize lipoadenomas. CLINICAL PRESENTATION: In this case report, we present three cases of functional parathyroid lipoadenomas. CONCLUSION: Preoperative imaging modalities often can't localize lipoadenoma...
May 16, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29775451/-recurrent-urolithiasis-as-a-symptom-of-primary-hyperparathyroidism-in-a-16-year-old-boy
#2
Monika Wojciechowska, Beata Bieniaś, Aleksandra Sobieszczańska-Droździel, Anna Wieczorkiewicz-Płaza, Iwona Beń-Skowronek, Przemysław Sikora
Primary hyperparathyroidism is one of the most common endocrine diseases, however, it is rare in children. In most cases, it is caused by adenoma of these organs. Its most common complications include urolithiasis, nephrocalcinosis and osteoporosis. CASE REPORT: A 16-year-old patient was admitted to our Clinic because of his first-ever renal colic. The ultrasound examination revealed rightsided hydronephrosis caused by the presence of 9 mm stone in the upper part of the right ureter. In addition, the presence of 8 mm stone in the middle calyx of the left kidney was found...
April 23, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29764395/longitudinal-changes-in-bone-and-mineral-metabolism-after-cessation-of-cinacalcet-in-dialysis-patients-with-secondary-hyperparathyroidism
#3
Irene Ruderman, Edward R Smith, Nigel D Toussaint, Tim D Hewitson, Stephen G Holt
BACKGROUND: The calcimimetic agent cinacalcet is effective for the management of secondary hyperparathyroidism (SHPT) in dialysis patients. Changes to reimbursement of cinacalcet in Australia provided an opportunity to assess effects of medication cessation on biochemical and clinical outcomes in dialysis patients, including changes to novel biomarkers such as calciprotein particles (CPP). CPP are nanoparticles of mineral and protein in the circulation associated with increased vascular calcification in patients with chronic kidney disease...
May 15, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29762046/effects-of-calcimimetics-on-long-term-outcomes-in-dialysis-patients-literature-review-and-bayesian-meta-analysis
#4
Greta Lozano-Ortega, Nathalie Waser, Mark E Bensink, Sarah Goring, Heather Bennett, Geoffrey A Block, Glenn M Chertow, Marie-Louise Trotman, Kerry Cooper, Adrian R Levy, Vasily Belozeroff
AIM: Randomized controlled trials (RCTs) with clinical outcomes are considered the gold standard for regulatory approval. However, by design they are only able to answer a small number of clinical questions. Other high-quality studies are required for clinical decision-making. The EVOLVE was the largest RCT, evaluating the effects of cinacalcet on clinical outcomes among adult patients receiving maintenance dialysis suffering from secondary hyperparathyroidism. While the EVOLVE trial did not reach its primary end point, imbalance in subjects' age at randomization and discontinuation rates are two of the reasons that the lack of mortality benefit is in question...
May 15, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29757946/role-of-venous-sampling-in-the-diagnosis-of-endocrine-disorders
#5
REVIEW
Ryan W England, Eliza B Geer, Amy R Deipolyi
Venous sampling is the gold standard for localizing abnormal hormone secretion in several endocrine disorders. The most common indication for venous sampling is in the workup of primary aldosteronism, adrenocorticotropic hormone-dependent Cushing's syndrome, and hyperparathyroidism. In experienced hands, venous sampling is safe and accurate. This review discusses the role of venous sampling in the workup of endocrine disease, describing the underlying anatomy and pathophysiology, as an understanding of these concepts is essential for technical and clinical success...
May 14, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29756350/selective-parathyroid-venous-sampling-in-primary-hyperparathyroidism-a-systematic-review-and-meta-analysis
#6
REVIEW
Kareem Ibraheem, Eman A Toraih, Antoine B Haddad, Mahmoud Farag, Gregory W Randolph, Emad Kandil
OBJECTIVE: Minimally invasive parathyroidectomy requires accurate preoperative localization techniques. There is considerable controversy about the effectiveness of selective parathyroid venous sampling (sPVS) in primary hyperparathyroidism (PHPT) patients. The aim of this meta-analysis is to examine the diagnostic accuracy of sPVS as a preoperative localization modality in PHPT. METHODS: Studies evaluating the diagnostic accuracy of sPVS for PHPT were electronically searched in the PubMed, EMBASE, Web of Science, and Cochrane Controlled Trials Register databases...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29750642/trueness-precision-and-stability-of-the-liaison-1-84-parathyroid-hormone-pth-third-generation-assay-comparison-to-existing-intact-pth-assays
#7
Andre Valcour, Claudia Zierold, Frank A Blocki, Douglas M Hawkins, Kevin J Martin, Sudhaker D Rao, Fabrizio Bonelli
BACKGROUND: Over the past few decades, parathyroid hormone (PTH) immunoassays have progressed through successive generations resulting in increased specificity and accuracy for detecting circulating PTH. With the introduction of third-generation assays, in which the biologically active PTH(1-84) is specifically targeted, the PTH(7-84) and other fragments are not detected. The specific recognition of only PTH(1-84) whole molecule allows for more reliable standardization and calibration than with the existing assays...
May 11, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29745791/prevention-and-management-of-osteoporosis-and-osteoporotic-fractures-in-persons-with-a-spinal-cord-injury-or-disorder-a-systematic-scoping-review
#8
Nour Zleik, Frances Weaver, Robert L Harmon, Brian Le, Reshmitha Radhakrishnan, Wanda D Jirau-Rosaly, B Catharine Craven, Mattie Raiford, Jennifer N Hill, Bella Etingen, Marylou Guihan, Michael H Heggeness, Cara Ray, Laura Carbone
OBJECTIVES: The primary objective was to review the literature regarding methodologies to assess fracture risk, to prevent and treat osteoporosis and to manage osteoporotic fractures in SCI/D. STUDY DESIGN: Scoping review. Settings/Participants: Human adult subjects with a SCI/D. OUTCOME MEASURES: Strategies to identify persons with SCI/D at risk for osteoporotic fractures, nonpharmacological and pharmacological therapies for osteoporosis and management of appendicular fractures...
May 10, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29737315/applicability-of-transoral-endoscopic-parathyroidectomy-through-vestibular-route-for-primary-sporadic-hyperparathyroidism-a-south-indian-experience
#9
P R K Bhargav, M Sabaretnam, V Amar, N Vimala Devi
Introduction: Primary hyperparathyroidism is one of the most common endocrine disorders requiring surgical parathyroidectomy for its definitive treatment. Surgical exploration is traditionally performed through conventional open neck approach. A wide range of minimal access and minimally invasive endoscopic techniques (gas less and with gas) have been attempted in the past two decades. In this context, we evaluated the feasibility and safety of an innovative transoral endoscopic parathyroidectomy (EP) technique, which represents a paradigm shift in transluminal endocrine surgery...
May 4, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29736849/diagnostic-accuracy-of-3t-magnetic-resonance-imaging-in-the-preoperative-localisation-of-parathyroid-adenomas-comparison-with-ultrasound-and-99mtc-sestamibi-scans
#10
Renato Argirò, Daniele Diacinti, Beatrice Sacconi, Angelo Iannarelli, Davide Diacinti, Cristiana Cipriani, Daniela Pisani, Elisabetta Romagnoli, Marco Biffoni, Cira Di Gioia, Jessica Pepe, Mario Bezzi, Claudio Letizia, Salvatore Minisola, Carlo Catalano
OBJECTIVES: To evaluate the diagnostic performance of 3TMRI in comparison with ultrasound (US) and 99mTc-sestamibi scan for presurgical localisation of parathyroid adenomas (PTAs) in patients with primary hyperparathyroidism (PHPT). METHODS: Fifty-seven patients affected by PHPT were prospectively enrolled and underwent US, 99mTc-sestamibi and 3TMRI. T2-weighted and post-contrast T1-weighted Iterative decomposition of water and fat with Echo Asymmetry and Least squares estimation (IDEAL) sequences were acquired...
May 7, 2018: European Radiology
https://www.readbyqxmd.com/read/29735505/osteitis-fibrosa-cystica-masquerading-as-bone-neoplasm
#11
Vishnu Vardhan Garla, Israh Akhtar, Sohail Salim, Angela Subauste
A 50-year-old female patient with no significant medical history presented with left knee pain. Radiographs of the knee showed a circumferential swelling of the distal femur suggestive of neoplasia. Further evaluation revealed multiple lesions in the left iliac bone and proximal femur. Biopsy was suggestive of a reparative granuloma or an aneurysmal bone cyst. Laboratory assessment showed hypercalcaemia and elevated parathyroid hormone consistent with severe primary hyperparathyroidism. Osseous survey was significant for salt and pepper appearance of the skull...
May 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29734476/prevalence-and-risk-of-vertebral-fractures-in-primary-hyperparathyroidism-a-nested-case-control-study
#12
Henriette Ejlsmark-Svensson, Lise Sofie Bislev, Siv Lajlev, Torben Harsløf, Lars Rolighed, Tanja Sikjaer, Lars Rejnmark
Introduction Prevalence of vertebral fractures (VFx) in primary hyperparathyroidism (PHPT) remains uncertain. We aimed to estimate the prevalence of VFx, investigate potential risk factors associated with VFx and whether bone mineral density (BMD) differs between PHPT- and osteoporotic-patients with VFx. Methods Through the Danish National Patient Register, we identified patients diagnosed with PHPT between 2005-2015. The diagnosis was verified by reviewing biochemical findings and X-ray reports were reviewed by two investigators...
May 7, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29732354/the-prevalence-of-primary-hyperparathyroidism-in-korea-a-population-based-analysis-from-patient-medical-records
#13
Jong-Kyu Kim, Young Jun Chai, Jung Kee Chung, Ki-Tae Hwang, Seung Chul Heo, Su-Jin Kim, June Young Choi, Ka Hee Yi, Sang Wan Kim, Sung Yong Cho, Kyu Eun Lee
Purpose: Because primary hyperparathyroidism (PHPT) is difficult to recognize, it has a high likelihood of being underdiagnosed. In this study, we estimated the incidence of PHPT and evaluated PHPT diagnosis in Korea. Methods: To calculate the prevalence of PHPT, we examined the medical records of patients that were hospitalized for urolithiasis between 2013 and 2016 at a single institute, and then identified those who were diagnosed with PHPT from the same group...
May 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29730179/complementary-role-of-parathormone-washout-test-to-99m-tc-mibi-parathyroid-scintigraphy-and-histopathologic-analysis-of-cell-types-in-parathyroid-adenomas
#14
Semra Ince, Ozdes Emer, Salih Deveci, Kursat Okuyucu, Engin Alagoz, Huseyin San, Aslı Ayan, Ozgur Karacalioglu, Cem Haymana, Bengul Gunalp, Nuri Arslan
OBJECTIVE: Parathyroid scintigraphy (PS) can be negative or equivocal (N/E) in a considerable number of cases with highly suspicious clinical findings and biochemical results for parathyroid adenoma (PA). The aims of this study were to investigate the complementary role of parathormone washout test (PWT) to PS in patients with primary hyperparathyroidism (PHPT) and evaluate histopathologic aspects of PAs in comparison with PS results. MATERIAL AND METHODS: Thirty-eight patients with PHPT referred for PS were included in the study...
May 2, 2018: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/29727008/pro-fhh-a-risk-equation-to-facilitate-the-diagnosis-of-parathyroid-related-hypercalcemia
#15
Jean-Philippe Bertocchio, Muriel Tafflet, Eugénie Koumakis, Gérard Maruani, Rosa Vargas-Poussou, Caroline Silve, Peter H Nissen, Stéphanie Baron, Caroline Prot-Bertoye, Marie Courbebaisse, Jean-Claude Souberbielle, Lars Rejnmark, Catherine Cormier, Pascal Houillier
Context: Parathyroid-related hypercalcemia is due to primary hyperparathyroidism (PHPT) or to familial hypocalciuric hypercalcemia (FHH). PHPT can lead to complications that necessitate parathyroidectomy. FHH is a rare genetic disease resembling PHPT; surgery is ineffective. A reliable method for distinguishing FHH from PHPT is needed. Objective: To develop an easy-to-use tool to predict if a patient has PHPT. Design: Retrospective analysis of two prospective cohorts...
May 2, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29723896/mineralocorticoid-receptor-blockers-and-aldosterone-to-renin-ratio-a-randomized-controlled-trial-and-observational-data
#16
Stefan Pilz, Christian Trummer, Nicolas Verheyen, Verena Schwetz, Marlene Pandis, Felix Aberer, Martin R Grübler, Andreas Meinitzer, Antonia Bachmann, Jakob Voelkl, Ioana Alesutan, Cristiana Catena, Leonardo A Sechi, Winfried März, Barbara Obermayer-Pietsch, Andreas Tomaschitz
Current guidelines recommend to withdraw mineralocorticoid receptor (MR) blocker treatment for at least 4 weeks when measuring the aldosterone to renin ratio (ARR) as a screening test for primary aldosteronism (PA). We aimed to evaluate the effect of MR blocker treatment on ARR and its components, plasma aldosterone concentration (PAC), and direct renin concentration (DRC). First, we performed a post-hoc analysis of the effect of eplerenone on parathyroid hormone levels in primary hyperparathyroidism (EPATH) study, a randomized controlled trial (RCT) in 110 patients with primary hyperparathyroidism (pHPT)...
May 3, 2018: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29722489/-study-of-diagnostic-value-of-natremia-in-a-cohort-of-patients-with-hypercalcemia
#17
A Le, B Couturier, E Cogan, F Vandergheynst
INTRODUCTION: Hypercalcemia is a common pathological condition in clinical practice. The two most common causes are primary hyperparathyroidism and cancer. SIADH is often encountered in cancer cases and is the most common cause of hyponatremia. The aim of this study is to evaluate serum sodium levels in a cohort of patients with hypercalcemia and consider its predictive value in determining the origin of this hypercalcemia. MATERIALS AND METHODS: We performed a retrospective study on a series of 15...
2018: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/29721808/the-characteristics-of-clinical-changes-in-primary-hyperparathyroidism-in-chinese-patients
#18
Xiao-Ai Yao, Bo-Jun Wei, Tao Jiang, Hong Chang
In Western countries, the presentation of primary hyperparathyroidism (PHPT) changed from a symptomatic to an asymptomatic disease after the 1970s, whereas in China, only one study has evaluated the changing clinical characteristics and biochemical profiles of PHPT patients. The aim of this study was to explore changes in the clinical characteristics of PHPT in Chinese patients. Overall, 140 consecutive patients with PHPT were studied between January 1, 2010 and June 30, 2016. The patients were divided into two groups: 32 consecutive patients from January 1, 2010 to March 31, 2013 were included in group 1, and 108 consecutive patients from April 1, 2013 to June 30, 2016 were included in group 2...
May 2, 2018: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29709532/-severe-hypercalcemia-of-unusual-cause-looking-for-the-culprit-case-report-and-review-of-the-literature
#19
M Jalbert, A Mignot, A-S Gauchez, A-C Dobrokhotov, J Fourcade
INTRODUCTION: Hypercalcemia is not a rare event and can lead to severe consequences. Its main etiologies are primary hyperparathyroidism and neoplasic conditions. The iatrogenic etiology by vitamin D intoxication is more rarely found. CASE PRESENTATION: A 76-year-old finish woman comes to the emergency room for chest pain. Her medical history is impossible to specify due to the language barrier and initial confusion. She has severe hypercalcaemia (4.14mmol/L), renal insufficiency, cardiac arrhythmia later complicated by an ischemic cardiac episode...
April 27, 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29699804/preoperative-localization-modalities-in-primary-hyperparathyroidism-correlation-with-postoperative-cure
#20
Abbas Al-Kurd, Barak Levit, May Assaly, Ido Mizrahi, Haggi Mazeh, Michal Mekel
BACKGROUND: Accurate preoperative localization is critical to the success of minimally invasive parathyroidectomy. This investigation aimed to assess the correlation among preoperative imaging results, intraoperative findings, and postoperative cure rates in patients undergoing operation for primary hyperparathyroidism. METHODS: A retrospective review of all patients who underwent operation for primary hyperparathyroidism between June 2010 and March 2016 was performed...
April 23, 2018: Surgery
keyword
keyword
1087
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"