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Esophageal cancer surgery

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https://www.readbyqxmd.com/read/28804629/clinical-presentation-and-treatment-of-gastric-metastasis-from-other-malignancies-of-solid-organs
#1
Tsutomu Namikawa, Eri Munekage, Maho Ogawa, Toyokazu Oki, Masaya Munekage, Hiromichi Maeda, Hiroyuki Kitagawa, Takeki Sugimoto, Michiya Kobayashi, Kazuhiro Hanazaki
The aim of the present study was to analyze the clinicopathologic features and treatment outcomes of gastric metastasis from other malignancies of solid organs. A review was conducted of patients with metastatic tumors in the stomach from other malignancies of solid organs detected endoscopically at the Department of Surgery, Kochi Medical School, from January 1991 to December 2015. Seven patients (four men and three women), with a median age of 64 years (range, 42-71 years), had metastatic gastric tumors. Median tumor size was 7...
August 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28802289/home-enteral-nutrition-s-effects-on-nutritional-status-and-quality-of-life-after-esophagectomy
#2
Jian Zeng, Jian Hu, Qixun Chen, Jianguo Feng
BACKGROUND AND OBJECTIVES: We aimed to characterize the effect of home enteral nutrition (HEN) on the nutritional status and the quality of life (QOL) of esophageal cancer patients who underwent Ivor Lewis esophagectomy for cancer. METHODS AND STUDY DESIGN: Sixty patients with esophageal cancer were assigned to receive either HEN (n=30) or standard care only (n=30) from 1 week to 24 weeks following surgery. Nutritional status was evaluated using The Mini Nutritional Assessment at 1 week preoperatively and at 12 and 24 weeks postoperatively...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28797755/failure-to-rescue-in-patients-undergoing-surgery-for-esophageal-or-gastric-cancer
#3
L A Busweiler, D Henneman, J L Dikken, M Fiocco, M I van Berge Henegouwen, B P Wijnhoven, R van Hillegersberg, C Rosman, M W Wouters, J W van Sandick
BACKGROUND: Complex surgical procedures such as esophagectomy and gastrectomy for cancer are associated with substantial morbidity and mortality. The purpose of this study was to evaluate trends in postoperative morbidity, mortality, and associated failure-to-rescue (FTR), in patients who underwent a potentially curative resection for esophageal or gastric cancer in the Netherlands, and to investigate differences between the two groups. METHODS: All patients with esophageal or gastric cancer who underwent a potentially curative resection, registered in the Dutch Upper GI Cancer Audit (DUCA) between 2011 and 2014, were included...
July 29, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28795280/the-use-of-neoadjuvant-therapy-for-resectable-locally-advanced-thoracic-esophageal-squamous-cell-carcinoma-in-an-analysis-of-5016-patients-from-305-designated-cancer-care-hospitals-in-japan
#4
Yoichiro Tsukada, Takahiro Higashi, Hideaki Shimada, Yoshinori Kikuchi, Atsuro Terahara
BACKGROUND: Recent studies have shown the benefits of neoadjuvant therapy with chemotherapy or chemoradiotherapy for resectable locally advanced thoracic esophageal squamous cell carcinoma (ESCC). The aim of our study was to elucidate the use of neoadjuvant therapy for thoracic ESCC in Japan. METHODS: Data on patients with stage IB-III thoracic ESCC were retrieved from the national database of hospital-based cancer registries combined with claims data between 2012 and 2013...
August 9, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28790297/-techniques-for-preventing-postoperative-complication-in-esophageal-salvage-surgery
#5
Mitsuru Iwama, Takushi Yasuda, Osamu Shiraishi, Hiroaki Kato, Yoko Hiraki, Yumiko Tanaka, Atsushi Yasuda, Masayuki Shinkai, Motohiro Imano, Yutaka Kimura, Haruhiko Imamoto
Patients with esophageal cancer are often treated with definitive chemoradiotherapy (dCRT). Regardless of arrival at dCRT, the risk of local/regional recurrence during follow-up is significant. Many patient are faced with limited options for therapy once dCRT has failed. Salvage surgery is the only way for complete cure of patients with local/regional recurrent esophageal cancer after dCRT. However, salvage surgery has a significant high risk of fatal complications. We examine our preventive measures to reduce the incidence of postoperative complications after salvage surgery for thoracic esophageal cancer...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28790296/-clinical-practice-of-enhanced-recovery-after-surgery-program-for-esophagectomy
#6
Masato Nishida, Yasuyuki Seto
Enhanced recover after surgery(ERAS) program is multimodal strategies to reduce the incidence of postoperative morbidity and mortality, and encourage early functional recovery from surgical insult. It consists of physical therapy to facilitate postoperative early mobilization, nutritional support, introduction of minimal invasive surgery, restrictive fluid therapy and early resumption of oral intake. Esophagectomy for esophageal cancer is a highly invasive procedure with high incidence of postoperative morbidity and mortality...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28790295/-perioperative-management-team-in-esophageal-cancer-surgery
#7
Akihiko Okamura, Masayuki Watanabe
Esophagectomy for patients with esophageal cancer is one of the most invasive surgery. Despite advances in surgical techniques and perioperative management, both morbidity and mortality rates after esophagectomy still remains high. Recently, it was suggested that perioperative care bundle is effective for preventing postoperative complications after esophagectomy. Then, we introduced a perioperative multidisciplinary management team, which aimed at systematic perioperative care for patients undergoing esophagectomy...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28777676/benefits-of-supplemental-jejunostomy-tube-feeding-during-neoadjuvant-therapy-in-patients-with-locally-advanced-potentially-resectable-esophageal-cancer
#8
Brian G A Dalton, Adam J Friedant, Stacey Su, Tiffany A P Schatz, Karen J Ruth, Walter J Scott
BACKGROUND: Standard treatment for locally advanced esophageal cancer includes neoadjuvant therapy followed by surgical resection. However, many patients experience a period of decreased oral intake during neoadjuvant treatment and are at risk for malnutrition. We hypothesize that use of jejunostomy tube (j-tube) feedings during neoadjuvant therapy in selected patients may be associated with better perioperative outcomes. METHODS: A prospectively collected database at a single institution was retrospectively analyzed...
August 4, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28771617/late-week-surgical-treatment-of-endometrial-cancer-is-associated-with-worse-long-term-outcome-results-from-a-prospective-multicenter-study
#9
Tormund S Njølstad, Henrica M Werner, Janusz Marcickiewicz, Solveig Tingulstad, Anne C Staff, Klaus Oddenes, Line Bjørge, Marie E Engh, Kathrine Woie, Jostein Tjugum, Margaret S Lode, Frederic Amant, Helga B Salvesen, Jone Trovik
Surgery is the cornerstone in primary endometrial cancer treatment, and with curative intent it constitutes total hysterectomy and bilateral salpingo-oopherectomy. In addition, lymphadenectomy is performed in selected patients dependent on a preoperative risk assessment. Recent reports from the surgical approach to esophageal cancer reveal worse outcome when esophagectomy is performed later in the week. On this basis, we set out to explore weekday of surgery in relation to long-term outcome in 1302 endometrial cancer patients prospectively included in the MoMaTEC multicenter study...
2017: PloS One
https://www.readbyqxmd.com/read/28770295/inclusion-of-pet-ct-into-planning-of-primary-or-neoadjuvant-chemoradiotherapy-of-esophageal-cancer-improves-prognosis
#10
Jan-Christopher Metzger, Daniel Wollschläger, Matthias Miederer, Peter Vaupel, Markus Moehler, Heinz Schmidberger, Arnulf Mayer
BACKGROUND: PET-CT is widely used for both the staging and planning of primary or neoadjuvant chemoradiotherapy for esophageal cancer. Inclusion of PET-CT information into radiotherapy planning often leads to substantial modifications of the target volume. In the case of detection of distant metastases, it may also result in a switch to a palliative treatment approach. This spares patients from therapy-related toxicities that provide no clinical benefit. However, due to a lack of studies, it is currently unclear whether the advantages of PET-CT also translate into a measurable improvement in patient survival...
August 2, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28770168/neoadjuvant-therapy-for-esophageal-adenocarcinoma-in-the-community-setting-practice-and-outcomes
#11
Joe Abdo, Carrie A Bertellotti, David L Cornell, Devendra K Agrawal, Sumeet K Mittal
There has been an alarming rise in the incidence of esophageal adenocarcinoma which continues to have poor survival rates primarily due to lack of effective chemotherapy and presentation at advanced stages. Over a dozen chemotherapeutic agents are FDA approved for esophageal cancer (EC), and a two or three-drug combination is typically prescribed as first-line therapy for the majority of EC patients, administered either pre or post-operatively with esophageal resection. We have noticed significant variability in adjuvant and neoadjuvant regimens used in the community setting...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28766083/do-male-esophageal-cancer-patients-have-impaired-sexual-function-after-esophagectomy-a-self-reported-outcomes-study
#12
Xun Cao, Jiu-Di Zhong, Tian-Zhen Yang, Yu-Chuan Jiang, Zhe-Sheng Wen
PURPOSE: Sexual function is a significant part of patients' quality of life, which is another important aspect of cancer. This study assessed and compared the sexual function of male esophageal cancer patients to that of age-matched normal controls through postoperative follow-up surveys. METHODS: The study included 105 male esophageal cancer patients aged 38-81 years who underwent a curative-intent esophagectomy between April 2012 and May 2014. This observational study included sociodemographic and clinicopathological characteristics and responses to sexual function questionnaires International Index of Erectile Function (IIEF) at 6 and 12 months after surgery...
August 1, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28763327/advanced-age-is-not-a-contraindication-for-treatment-with-curative-intent-in-esophageal-cancer
#13
Francine E M Voncken, Rosa T van der Kaaij, Karolina Sikorska, Erik van Werkhoven, Jolanda M van Dieren, Cecile Grootscholten, Petur Snaebjornsson, Johanna W van Sandick, Berthe M P Aleman
OBJECTIVES: The objective of this study is to compare long-term outcomes between younger and older (70 y and above) esophageal cancer patients treated with curative intent. MATERIALS AND METHODS: Overall survival (OS), disease-free survival (DFS), and locoregional recurrence-free interval were compared between older (70 y and above) and younger (below 70 y) esophageal cancer patients treated between 1998 and 2013. Treatment consisted of neoadjuvant chemoradiotherapy with surgery or definitive chemoradiotherapy: 36 to 50...
July 31, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28759156/exclusive-right-thoracic-approach-for-esophagus-surgery
#14
Chuan Li, Nan Ge, Yi Shen, Wenjie Jiao
An exclusive right thoracic approach for esophagus surgery is rarely used, with few reports of its use in China. We retrospectively reviewed the data of 21 esophageal cancer patients from January 2010 to January 2015. Their age ranged from 74-83 years (average 76.6). All of the patients had lower pulmonary function. After multidisciplinary team discussion, sufficient preoperative preparation, and assessment of cardiopulmonary reserve, an exclusive right thoracic approach for esophageal cancer resection was performed...
July 31, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/28755160/successful-video-assisted-thoracoscopic-surgery-in-prone-position-in-patients-with-esophageal-cancer-and-aberrant-right-subclavian-artery-report-of-three-cases
#15
Koji Shindo, Eishi Nagai, Toshinaga Nabae, Toru Eguchi, Taiki Moriyama, Kenoki Ohuchida, Tatsuya Manabe, Takao Ohtsuka, Yoshinao Oda, Makoto Hashizume, Masafumi Nakamura
BACKGROUND: An aberrant right subclavian artery (ARSA) with an associated nonrecurrent right inferior laryngeal nerve (NRILN) is a relatively rare anomaly that occurs at a frequency of 0.3 to 2.0% of the general population. NRILN has been mainly documented in the head and neck region; it has been rarely described in patients with esophageal cancer, especially those undergoing thoracoscopic surgery. Video-assisted thoracoscopic surgery for esophageal cancer (VATS-E) is becoming more widespread as a reliable minimally invasive surgical procedure associated with reduced perioperative complications...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28747054/towards-the-centralization-of-digestive-oncologic-surgery-changes-in-activity-techniques-and-outcome
#16
Cristian Tebé, Roger Pla, Josep Alfons Espinàs, Julieta Corral, Elisa Puigdomenech, Josep Maria Borràs, Joan M V Pons, Mireia Espallargues
The objective of the present study was to examine changes in the activity, surgical techniques and results from the process of centralization of complex digestive oncologic surgery in 2005-2012 as compared to 1996-2000. A retrospective cohort study employing the minimum basic data set of hospital discharge (MBDSHD 1996-2012) from public centers in Catalonia (Spain) was performed. The population consisted of individuals aged > 18 who underwent digestive oncologic surgery (esophagus, pancreas, liver, stomach or rectum)...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28744724/concordance-of-clinical-diagnosis-of-t-classification-among-physicians-for-locally-advanced-unresectable-thoracic-esophageal-cancer
#17
Tomoya Yokota, Takushi Yasuda, Hiroyuki Kato, Isao Nozaki, Hiroshi Sato, Yoshinori Miyata, Yoshifumi Kuroki, Ken Kato, Yasuo Hamamoto, Yasuhiro Tsubosa, Hirofumi Ogawa, Yoshinori Ito, Yuko Kitagawa
BACKGROUND: We conducted a multicenter phase II trial assessing chemoselection with docetaxel plus 5-fluorouracil and cisplatin induction chemotherapy and subsequent conversion surgery for locally advanced, unresectable esophageal cancer. The aim of this study was to validate the concordance of clinical T diagnosis among physicians in the cases of this trial. METHODS: Computed tomography scans and esophagoscopic images of 48 patients taken at baseline were centrally reviewed by 6 senior physicians with experience in esophageal oncology...
July 25, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28742698/survival-benefit-of-neoadjuvant-treatment-in-clinical-t3n0m0-esophageal-cancer-results-from-a-retrospective-multicenter-european-study
#18
Styliani Mantziari, Caroline Gronnier, Florence Renaud, Alain Duhamel, Jérémie Théreaux, Cécile Brigand, Nicolas Carrère, Jérémie H Lefevre, Arnaud Pasquer, Nicolas Demartines, Denis Collet, Bernard Meunier, Christophe Mariette
BACKGROUND: Based on current guidelines, clinical T3N0M0 esophageal tumors may or may not receive neoadjuvant treatment, according to their perception as locally advanced (cT3) or early-stage tumors (stage II). The study aim was to assess the impact of neoadjuvant treatment upon survival for cT3N0M0 esophageal cancer patients, with subgroup analyses by histological type (squamous cell carcinoma vs adenocarcinoma) and type of neoadjuvant treatment (chemotherapy vs radiochemotherapy). METHODS: Data from patients operated on for esophageal cancer in 30 European centers were collected...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28742697/are-thoracotomy-and-or-intrathoracic-anastomosis-still-predictors-of-postoperative-mortality-after-esophageal-cancer-surgery-a-nationwide-study
#19
Sébastien Degisors, Arnaud Pasquer, Florence Renaud, Hélène Béhal, Flora Hec, Anne Gandon, Marguerite Vanderbeken, Gilbert Caranhac, Alain Duhamel, Guillaume Piessen, Christophe Mariette
BACKGROUND: Intrathoracic (vs cervical) anastomosis and a thoracotomy (vs absence) have previously been associated with increasing postoperative mortality (POM). Recent improvements in surgical practices and perioperative management may have changed these dogmas. OBJECTIVES: The aim of this study was to evaluate the impact of performing intrathoracic anastomosis and/or thoracotomy on POM after esophageal cancer surgery in recent years. METHODS: All consecutive patients who underwent esophageal cancer surgery with reconstruction between 2010 and 2012 in France were included (n = 3286)...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28742685/recurrence-patterns-and-long-term-results-after-induction-chemotherapy-chemoradiotherapy-and-curative-surgery-in-patients-with-locally-advanced-esophageal-cancer
#20
Thomas Steffen, Daniel Dietrich, Annelies Schnider, Christoph Kettelhack, Olivier Huber, Walter R Marti, Markus Furrer, Beat Gloor, Marc Schiesser, Sandra Thierstein, Peter Brauchli, Thomas Ruhstaller
OBJECTIVE: The long-term follow up data of 2 prospective phase II trials is reported (NCT00072033, NCT00445861), which investigated neoadjuvant chemoradiation followed by surgery in patients with esophageal carcinoma. Postoperative complications as well as prognostic factors and patterns of relapse during long-term observation are shown. SUMMARY OF BACKGROUND DATA: Long-term follow-up is often missing in the complex setting of multimodal treatments of esophageal carcinoma; this leads to rather undifferentiated follow-up guidelines for this tumor entity...
July 24, 2017: Annals of Surgery
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