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Esophageal cancer surgery

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https://www.readbyqxmd.com/read/28070329/mastering-minimally-invasive-esophagectomy-requires-a-mentor-experience-of-a-personal-mentorship
#1
Miguel A Cuesta, Nicole van der Wielen, Jennifer Straatman, Donald L van der Peet
Since the first laparoscopic procedure, there has been an steady increase in advanced minimally invasive surgery. These procedures include oncological colorectal, hepatobiliary and upper gastrointestinal surgery. Implementation of these procedures requires different and new skills for the surgeons who wish to perform these procedures. To accomplish this surgical teaching program, a mentorship seems the most ideal method to teach the apprentice surgeon these specific skills. At the VU medical center a teaching program for a minimally-invasive esophagectomy for esophageal cancer started in 2009...
January 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28066592/mapping-patterns-of-nodal-metastases-in-esophageal-carcinoma-rethinking-the-clinical-target-volume-for-supraclavicular-nodal-irradiation
#2
Yijun Luo, Yuhui Liu, Xiaoli Wang, Bin Zhang, Jinming Yu, Chengang Wang, Yong Huang, Minghuan Li
BACKGROUND: To map detail distribution of metastatic supraclavicular (SCV) lymph nodes (LN) in esophageal cancer (EC) patients and determine the precise radiation therapy clinical target volume (CTV). METHODS: A total of 101 thoracic esophageal carcinoma patients after surgery experienced SCV LN metastasis were retrospectively examined. The SCV region is further divided into four subgroups. Using hand drawings registration, nodes were mapped to a template computed tomogram to provide a visual impression of nodal frequencies and anatomic distribution...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28064398/prognostic-significance-of-hyperfibrinogenemia-in-patients-with-esophageal-squamous-cell-carcinoma
#3
Takashi Suzuki, Hideaki Shimada, Tatsuki Nanami, Yoko Oshima, Satoshi Yajima, Naohiro Washizawa, Hironori Kaneko
BACKGROUND: Preoperative hyperfibrinogenemia is associated with inflammatory mediators and a poor prognosis in several types of cancer. However, there is no published information on the monitoring of patients with preoperative hyperfibrinogenemia after surgery. The aim of the study reported here was to assess the clinicopathological and prognostic significance of plasma fibrinogen levels in patients with esophageal squamous cell carcinoma before and after surgical treatment. METHODS: Plasma fibrinogen levels were analyzed before surgical treatment (endoscopic submucosal dissection and surgery) in 82 patients with esophageal squamous cell carcinoma...
January 7, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28059964/prognostic-value-of-pretreatment-pathological-tumor-extent-in-patients-treated-with-neoadjuvant-chemoradiotherapy-plus-surgery-for-esophageal-or-junctional-cancer
#4
Joel Shapiro, Katharina Biermann, David van Klaveren, G Johan A Offerhaus, Fiebo J W Ten Kate, Sybren L Meijer, Mark I van Berge Henegouwen, Ewout W Steyerberg, Bas P L Wijnhoven, J Jan B van Lanschot
OBJECTIVE: We aimed to determine pretreatment pathological tumor extent in the resection specimen after neoadjuvant chemoradiotherapy (nCRT) and to assess its prognostic value in patients with esophageal cancer. METHODS: Patients with esophageal cancer, treated with nCRT plus surgery were included (2003-2011). Pretreatment pathological T-stage (prepT-stage) and N-stage (prepN-stage) were estimated based on the extent of regressional changes and residual tumor cells in the resection specimen...
February 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28058562/effectiveness-of-repeat-18f-fluorodeoxyglucose-positron-emission-tomography-computerized-tomography-pet-ct-scan-in-identifying-interval-metastases-for-patients-with-esophageal-cancer
#5
Emmanuel Gabriel, Raed Alnaji, William Du, Kristopher Attwood, Moshim Kukar, Steven Hochwald
INTRODUCTION: An 18F-fluorodeoxyglucose positron emission tomography-computerized tomography (PET-CT) scan is performed after neoadjuvant chemoradiation (nCRT) to restage esophageal cancer. The purpose of this study was to determine the ability of PET-CT to accurately identify interval metastatic disease following nCRT. METHODS: This was a single-institution retrospective review (January 2005-February 2012) of patients with esophageal cancer treated with nCRT who underwent pre- and post-nCRT PET-CT...
January 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28054341/intermittent-pneumatic-compression-in-combination-with-low-molecular-weight-heparin-in-the-prevention-of-venous-thromboembolic-events-in-esophageal-cancer-surgery
#6
Kevin Parry, Amir-Hossein Sadeghi, Sylvia van der Horst, Jan Westerink, Jelle P Ruurda, Richard van Hillegersberg
INTRODUCTION: Aim of this study was to evaluate the use of Intermittent Pneumatic Compression (IPC) in the prevention of symptomatic venous thromboembolic events (VTE) in patients undergoing esophagectomy for cancer. METHODS: From a prospective database, all patients operated between 2010 and 2014 received IPC in addition to LMWH and were compared to a historical cohort of patients treated LMWH only (2004-2009). RESULTS: Of the 313 included patients, 195 (62%) received IPC...
January 5, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28053809/postoperative-quality-of-life-after-total-gastrectomy-compared-with-partial-gastrectomy-longitudinal-evaluation-by-european-organization-for-research-and-treatment-of-cancer-og25-and-sto22
#7
Jeong-Hwan Lee, Hyuk-Joon Lee, Yun Suk Choi, Tae Han Kim, Yeon-Ju Huh, Yun-Suhk Suh, Seong-Ho Kong, Han-Kwang Yang
PURPOSE: The European Organization for Research and Treatment of Cancer quality-of-life questionnaire-OG25 was developed to evaluate the quality of life in patients with stomach and esophageal cancer. The following are included in the OG25 but not in the STO22: odynophagia, choked when swallowing, weight loss, trouble eating with others, trouble swallowing saliva, trouble talking, and trouble with coughing. In this study, we evaluated the quality of life of gastrectomized patients using both, the OG25 and the STO22...
December 2016: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/28050659/ischemic-gastric-conditioning-by-preoperative-arterial-embolization-before-oncologic-esophagectomy-a-single-center-experience
#8
Julien Ghelfi, Pierre-Yves Brichon, Julien Frandon, Bastien Boussat, Ivan Bricault, Gilbert Ferretti, Sébastien Guigard, Christian Sengel
PURPOSE: Surgical esophagectomy is the gold standard treatment of early-stage esophageal cancer. The procedure is complicated with significant morbidity; the most severe complication being the anastomotic leakage. Anastomotic fistulas are reported in 5-25% of cases and are mainly due to gastric transplant ischemia. Here, we report our experience of ischemic pre-conditioning using preoperative arterial embolization (PreopAE) before esophagectomy. MATERIALS AND METHODS: The medical records of all patients who underwent oncologic esophagectomy from 2008 to 2015 were retrospectively reviewed...
January 3, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28030564/poorly-differentiated-medullary-phenotype-predicts-poor-survival-in-early-lymph-node-negative-gastro-esophageal-adenocarcinomas
#9
Christoph Treese, Pedro Sanchez, Patricia Grabowski, Erika Berg, Hendrik Bläker, Martin Kruschewski, Oliver Haase, Michael Hummel, Severin Daum
BACKGROUND: 5-year survival rate in patients with early adenocarcinoma of the gastro-esophageal junction or stomach (AGE/S) in Caucasian patients is reported to be 60-80%. We aimed to identify prognostic markers for patients with UICC-I without lymph-node involvement (N0). METHODS: Clinical data and tissue specimen from patients with AGE/S stage UICC-I-N0, treated by surgery only, were collected retrospectively. Tumor size, lymphatic vessel or vein invasion, grading, classification systems (WHO, Lauren, Ming), expression of BAX, BCL-2, CDX2, Cyclin E, E-cadherin, Ki-67, TP53, TP21, SHH, Survivin, HIF1A, TROP2 and mismatch repair deficiency were analyzed using tissue microarrays and correlated with overall and tumor related survival...
2016: PloS One
https://www.readbyqxmd.com/read/28028639/relationship-between-abo-blood-group-and-clinicopathological-factors-and-their-effect-on-the-survival-of-japanese-patients-with-esophageal-squamous-cell-carcinoma
#10
Fumiaki Shiratori, Hideaki Shimada, Satoshi Yajima, Takashi Suzuki, Yoko Oshima, Tatsuki Nanami, Masaaki Ito, Hironori Kaneko
PURPOSE: Several studies have evaluated the association between ABO blood group and the prognosis of various types of cancer; however, little is known about the relationship between ABO blood group and esophageal squamous cell carcinoma (SCC). We investigated how ABO blood group and clinicopathological characteristics are related to the survival of Japanese patients with esophageal SCC. METHODS: We reviewed the medical records of 181 patients who underwent surgery for esophageal SCC between June, 2004 and December, 2015 and analyzed the association between ABO blood group and clinicopathological factors...
December 27, 2016: Surgery Today
https://www.readbyqxmd.com/read/28028281/-sequential-post-operative-nutrition-care-at-home-for-patients-receiving-surgical-treatment-for-esophageal-cancer
#11
Mio Matsuoka, Shohei Iijima
OBJECTIVE AND METHODS: We evaluated the outcomes of sequential nutrition care provided at home to patients who had undergone surgery for esophageal cancer. For 44 such patients, we investigated caloric intake(kcal), percentage of preoperative body weight(%), and requests and complains related to home nutrition care every 3 months for 1 year after surgery. RESULTS: Duringthe observation period, the mean postoperative caloric intake decreased to a minimum level at 1 month, but nearly recovered to the baseline at 12 months...
December 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28013492/meta-analysis-for-the-therapeutic-effect-of-neoadjuvant-therapy-in-resectable-esophageal-cancer
#12
Yusen Zhu, Min Liu, Xiaojing Yun, Dongmei Wang, Yuhuan Bai, Guizhi Zhang, Bei Ji, Changchun Jing
We aimed to review the therapeutic effects of neoadjuvant chemoradiotherapy (NCRT), chemotherapy (NCT), and radiotherapy (NRT) on patients with resectable Esophageal cancer (EsC) by comparison with surgery alone (SA). PubMed, EMBASE and Cochrane were searched for eligible studies published up to March 2015. Cochrane reviews were used for quality assessment. Eight primary outcomes were analyzed. Risk ratios (RRs)/ hazard ratios (HRs) and corresponding 95% confidence intervals (95% CIs) were calculated using the random- or fixed- effects model...
December 24, 2016: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28012715/hospital-costs-of-complications-after-esophagectomy-for-cancer
#13
L Goense, W A van Dijk, J A Govaert, P S N van Rossum, J P Ruurda, R van Hillegersberg
OBJECTIVE: The purpose of this study was to estimate the economic burden of postoperative complications after esophagectomy for cancer, in order to optimally allocate resources for quality improvement initiatives in the future. METHODS: A retrospective analysis of prospectively collected clinical and financial outcomes after esophageal cancer surgery in a tertiary referral center in the Netherlands was performed. Data was extracted from consecutive patients registered in the Dutch Upper GI Cancer Audit between 2011 and 2014 (n = 201)...
December 5, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28009737/clinicopathological-features-of-cervical-esophageal-cancer-retrospective-analysis-of-63-consecutive-patients-who-underwent-surgical-resection
#14
Hiroshi Saeki, Satoshi Tsutsumi, Takafumi Yukaya, Hirotada Tajiri, Ryosuke Tsutsumi, Sho Nishimura, Yu Nakaji, Kensuke Kudou, Shingo Akiyama, Yuta Kasagi, Yuichiro Nakashima, Masahiko Sugiyama, Hideto Sonoda, Kippei Ohgaki, Eiji Oki, Ryuji Yasumatsu, Torahiko Nakashima, Masaru Morita, Yoshihiko Maehara
OBJECTIVE: The objectives of this retrospective study were to elucidate the clinicopathological features and recent surgical results of cervical esophageal cancer. SUMMARY BACKGROUND DATA: Cervical esophageal cancer has been reported to have a dismal prognosis. Accurate knowledge of the clinical characteristics of cervical esophageal cancer is warranted to establish appropriate therapeutic strategies. METHODS: The clinicopathological features and treatment results of 63 consecutive patients with cervical esophageal cancer (Ce group) who underwent surgical resection from 1980 to 2013 were analyzed and compared with 977 patients with thoracic or abdominal esophageal cancer (T/A group) who underwent surgical resection during that time...
January 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28003586/current-status-and-future-prospects-for-esophageal-cancer-treatment
#15
Makoto Sohda, Hiroyuki Kuwano
The local control effect of esophagectomy with three-field lymph node dissection (3FLD) is reaching its limit pending technical advancement. Minimally invasive esophagectomy (MIE) by thoracotomy is slowly gaining acceptance due to advantages in short-term outcomes. Although the evidence is slowly increasing, MIE is still controversial. Also, the results of treatment by surgery alone are limiting, and multimodality therapy, which includes surgical and non-surgical treatment options including chemotherapy, radiotherapy, and endoscopic treatment, has become the mainstream therapy...
December 21, 2016: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28002320/ca125-is-a-potential-biomarker-to-predict-surgically-incurable-gastric-and-cardia-cancer-a-retrospective-study
#16
Taobo Luo, Wenhu Chen, Lifang Wang, Hongguang Zhao
Preoperative evaluation of the curability of gastric and cardia cancer is important to avoid risks of unnecessary surgery. Our previous study has reported several clinical parameters associated with incurable gastric surgery. In this study, we aimed to evaluate the correlation between CA125 and the curability of gastric and cardia cancer.A total of 297 cases of gastric and cardia cancer were analyzed retrospectively, including 153 cases with radical surgery and 144 with surgery for incurable gastric or cardia cancer...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27999650/subclavian-artery-esophageal-fistula-after-placement-of-a-self-expanding-metal-stent-in-a-patient-with-esophagogastric-anastomosis-stenosis
#17
Mohammadreza Seyedmajidi, Maryam Tavassoli, Mojtaba Kianti, Jamshid Vafaeimanesh
BACKGROUND: There have been reports on stent-related vascular erosions about patients with benign or malignant stenosis of the esophagus who received endoscopic stent insertion for palliative intention for oral intake. CASE PRESENTATION: A 61-year-old woman with esophageal cancer located in the middle part of esophagus was treated with esophagectomy. Two years following the surgery, malignant stenosis recurred in the esophagogastric anastomosis. A non-covered self-expanding metal stent (10 cm length with a diameter of 18 mm at expanded state) was inserted...
2016: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/27995191/non-radical-stepwise-complete-endoscopic-resection-of-barrett-s-epithelium-in-short-segment-barrett-s-esophagus-has-a-low-stricture-rate
#18
Andreas Koutsoumpas, Lai Mun Wang, Adam A Bailey, Richard Gillies, Robert Marshall, Michael Booth, Bruno Sgromo, Nick Maynard, Barbara Braden
Background and aims: Radical endoscopic excision of Barrett's epithelium performing 4 - 6 endoscopic resections during the same endoscopic session results in complete Barrett's eradication but has a high stricture rate (40 - 80 %). Therefore radiofrequency ablation is preferred after endoscopic mucosal resection (EMR) of visible nodules. We investigated the clinical outcome of non-radical, stepwise endoscopic mucosal resection with a maximum of two endoscopic resections per endoscopic session. Methods: We analysed our prospectively maintained database of patients undergoing esophageal EMR for early neoplasia in Barrett's esophagus from 2009 to 2014...
December 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27992300/identification-of-the-lymphatic-drainage-pattern-of-esophageal-cancer-with-near-infrared-fluorescent-imaging
#19
Francisco Schlottmann, Arianna Barbetta, Benedetto Mungo, Anne O Lidor, Daniela Molena
OBJECTIVE: Nodal status is one of the most important long-term prognostic factors for esophageal cancer. The aim of this study was to evaluate the ability of near-infrared (NIR) light fluorescent imaging to identify the lymphatic drainage pattern of esophageal cancer. METHODS: Patients with distal esophageal cancer or esophagogastric junction cancer scheduled for esophagectomy were enrolled in this study. Before surgery, an endoscopy was performed with submucosal injection of 2 cc of indocyanine green (ICG) around the tumor...
December 19, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27991695/application-of-extended-bi-pedicle-anterolateral-thigh-free-flaps-for-reconstruction-of-large-defects-a-case-series
#20
Michele Maruccia, Georgios Orfaniotis, Pedro Ciudad, Fabio Nicoli, Emanuele Cigna, Giuseppe Giudice, Kidakorn Kiranantawat, Diego Ribuffo, Hung-Chi Chen
BACKGROUND: The anterolateral thigh flap is a workforce flap in reconstructive surgery, however, variations in it is vascular anatomy are not uncommon. These variations may affect flap design and survival, especially when large flaps are required. In some anatomical variants the anterolateral thigh flap is supplied by two separate dominant pedicles, and in these cases a bi-pedicle modification may be necessary to ensure complete flap viability. The aim of this report is to evaluate the outcomes, and present our approach in using bi-pedicle anterolateral thigh flaps as a method to reduce the risk of partial flap necrosis when reconstructing sizeable soft tissue defects...
December 19, 2016: Microsurgery
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