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https://www.readbyqxmd.com/read/27849464/a-review-of-unique-considerations-for-female-veterans-with-amputation
#1
Billie J Randolph, Leif M Nelson, M Jason Highsmith
This article explores unique considerations that face both women living with limb loss and their health care providers. This demographic of patient has a higher rate of artificial limb rejection, thus challenging providers to address needs for cosmesis and function that varies from those of male counterparts. Health care providers for women with amputations, such as the Veterans Affairs, must evolve health care delivery, research practices, and work jointly with industry in order to meet the needs of this population...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27847323/pigeonetics-takes-flight-evolution-development-and-genetics-of-intraspecific-variation
#2
REVIEW
Eric T Domyan, Michael D Shapiro
Intensive artificial selection over thousands of years has produced hundreds of varieties of domestic pigeon. As Charles Darwin observed, the morphological differences among breeds can rise to the magnitude of variation typically observed among different species. Nevertheless, different pigeon varieties are interfertile, thereby enabling forward genetic and genomic approaches to identify genes that underlie derived traits. Building on classical genetic studies of pigeon variation, recent molecular investigations find a spectrum of coding and regulatory alleles controlling derived traits, including plumage color, feather growth polarity, and limb identity...
November 12, 2016: Developmental Biology
https://www.readbyqxmd.com/read/27833537/forward-prediction-in-the-posterior-parietal-cortex-and-dynamic-brain-machine-interface
#3
He Cui
While remarkable progress has been made in brain-machine interfaces (BMIs) over the past two decades, it is still difficult to utilize neural signals to drive artificial actuators to produce predictive movements in response to dynamic stimuli. In contrast to naturalistic limb movements largely based on forward planning, brain-controlled neuroprosthetics mainly rely on feedback without prior trajectory formation. As an important sensorimotor interface integrating multisensory inputs and efference copy, the posterior parietal cortex (PPC) might play a proactive role in predictive motor control...
2016: Frontiers in Integrative Neuroscience
https://www.readbyqxmd.com/read/27815182/key-considerations-in-designing-a-somatosensory-neuroprosthesis
#4
Benoit P Delhaye, Hannes P Saal, Sliman J Bensmaia
In recent years, a consensus has emerged that somatosensory feedback needs to be provided for upper limb neuroprostheses to be useful. An increasingly promising approach to sensory restoration is to electrically stimulate neurons along the somatosensory neuraxis to convey information about the state of the prosthetic limb and about contact with objects. To date, efforts towards artificial sensory feedback have consisted mainly of demonstrating that some sensory information could be conveyed using a small number of stimulation patterns, generally delivered through single electrodes...
November 1, 2016: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/27807418/evaluating-emg-feature-and-classifier-selection-for-application-to-partial-hand-prosthesis-control
#5
Adenike A Adewuyi, Levi J Hargrove, Todd A Kuiken
Pattern recognition-based myoelectric control of upper-limb prostheses has the potential to restore control of multiple degrees of freedom. Though this control method has been extensively studied in individuals with higher-level amputations, few studies have investigated its effectiveness for individuals with partial-hand amputations. Most partial-hand amputees retain a functional wrist and the ability of pattern recognition-based methods to correctly classify hand motions from different wrist positions is not well studied...
2016: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/27799908/assessment-of-myoelectric-controller-performance-and-kinematic-behavior-of-a-novel-soft-synergy-inspired-robotic-hand-for-prosthetic-applications
#6
Simone Fani, Matteo Bianchi, Sonal Jain, José Simões Pimenta Neto, Scott Boege, Giorgio Grioli, Antonio Bicchi, Marco Santello
Myoelectric artificial limbs can significantly advance the state of the art in prosthetics, since they can be used to control mechatronic devices through muscular activity in a way that mimics how the subjects used to activate their muscles before limb loss. However, surveys indicate that dissatisfaction with the functionality of terminal devices underlies the widespread abandonment of prostheses. We believe that one key factor to improve acceptability of prosthetic devices is to attain human likeness of prosthesis movements, a goal which is being pursued by research on social and human-robot interactions...
2016: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/27798422/epidural-and-transcutaneous-spinal-electrical-stimulation-for-restoration-of-movement-after-incomplete-and-complete-spinal-cord-injury
#7
Winfried Mayr, Matthias Krenn, Milan R Dimitrijevic
PURPOSE OF REVIEW: The Purpose of this review is to outline and explain the therapeutic use of electrical spinal cord stimulation (SCS) for modification of spinal motor output. Central functional stimulation provides afferent input to posterior root neurons and is applied to improve volitional movements, posture and their endurance, control spasticity, and improve bladder function or perfusion in the lower limbs. Clinical accomplishments strongly depend on each individual's physiological state and specific methodical adaptation to that physiological state...
December 2016: Current Opinion in Neurology
https://www.readbyqxmd.com/read/27797958/the-neural-basis-of-perceived-intensity-in-natural-and-artificial-touch
#8
Emily L Graczyk, Matthew A Schiefer, Hannes P Saal, Benoit P Delhaye, Sliman J Bensmaia, Dustin J Tyler
Electrical stimulation of sensory nerves is a powerful tool for studying neural coding because it can activate neural populations in ways that natural stimulation cannot. Electrical stimulation of the nerve has also been used to restore sensation to patients who have suffered the loss of a limb. We have used long-term implanted electrical interfaces to elucidate the neural basis of perceived intensity in the sense of touch. To this end, we assessed the sensory correlates of neural firing rate and neuronal population recruitment independently by varying two parameters of nerve stimulation: pulse frequency and pulse width...
October 26, 2016: Science Translational Medicine
https://www.readbyqxmd.com/read/27747394/advice-to-walk-after-meals-is-more-effective-for-lowering-postprandial-glycaemia-in-type-2-diabetes-mellitus-than-advice-that-does-not-specify-timing-a-randomised-crossover-study
#9
Andrew N Reynolds, Jim I Mann, Sheila Williams, Bernard J Venn
AIMS/HYPOTHESIS: Regular physical activity is a cornerstone of diabetes management. We conducted a study to evaluate whether specifying the timing of walking in relation to meals enhances the benefits conferred by current physical activity guidelines. METHODS: A total of 41 adults with type 2 diabetes mellitus (mean ± SD age 60 ± 9.9 years; mean diabetes duration 10 years) participated in this randomised, crossover study. Randomisation was by a computer-generated protocol...
October 17, 2016: Diabetologia
https://www.readbyqxmd.com/read/27730646/vestibular-feedback-maintains-reaching-accuracy-during-body-movement
#10
Craig P Smith, Raymond F Reynolds
KEY POINTS: Reaching movements can be perturbed by vestibular input, but the function of this response is unclear. Here, we applied galvanic vestibular stimulation concurrently with real body movement while subjects maintained arm position either fixed in space or fixed with respect to their body. During the fixed-in-space conditions, galvanic vestibular stimulation caused large changes in arm trajectory consistent with a compensatory response to maintain upper-limb accuracy in the face of body movement...
October 12, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27667570/osteoblast-differentiation-at-a-glance
#11
Arkady Rutkovskiy, Kåre-Olav Stensløkken, Ingvar Jarle Vaage
Ossification is a tightly regulated process, performed by specialized cells called osteoblasts. Dysregulation of this process may cause inadequate or excessive mineralization of bones or ectopic calcification, all of which have grave consequences for human health. Understanding osteoblast biology may help to treat diseases such as osteogenesis imperfecta, calcific heart valve disease, osteoporosis, and many others. Osteoblasts are bone-building cells of mesenchymal origin; they differentiate from mesenchymal progenitors, either directly or via an osteochondroprogenitor...
September 26, 2016: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/27651305/an-eye-blinking-based-beamforming-control-protocol-for-hearing-aid-users-with-neurological-motor-disease-or-limb-amputation
#12
Jungmin Yoon, Kyoung Won Nam, Jun Chang Lee, Dong Pyo Jang, In Young Kim
For hearing-impaired individuals with neurological motor deficits or finger/arm amputation due to accident or disease, hearing aid adjustment using a conventional finger manipulation-based remote controller is unavailable, and a more dedicated, hands-free alternative is required. In this study, we propose an eye-blinking-based beamforming control scheme for hearing aid users. Three electroencephalogram signals measured around the ears were utilized to detect eye-blinking patterns based on a three-layer artificial neural network...
September 21, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27640345/assimilation-of-virtual-legs-and-perception-of-floor-texture-by-complete-paraplegic-patients-receiving-artificial-tactile-feedback
#13
Solaiman Shokur, Simone Gallo, Renan C Moioli, Ana Rita C Donati, Edgard Morya, Hannes Bleuler, Miguel A L Nicolelis
Spinal cord injuries disrupt bidirectional communication between the patient's brain and body. Here, we demonstrate a new approach for reproducing lower limb somatosensory feedback in paraplegics by remapping missing leg/foot tactile sensations onto the skin of patients' forearms. A portable haptic display was tested in eight patients in a setup where the lower limbs were simulated using immersive virtual reality (VR). For six out of eight patients, the haptic display induced the realistic illusion of walking on three different types of floor surfaces: beach sand, a paved street or grass...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27627990/small-sided-football-games-on-sand-are-more-physical-demanding-but-less-technical-specific-compared-to-artificial-turf
#14
Vincenzo Rago, António N Rebelo, Federico Pizzuto, Daniel Barreira
BACKGROUND: The use of sand has been suggested as fitness-enhancing surface in field-based team sports. However, concerns have arisen in regard whether physical responses associated to sand training are sport-specific. We compared physical and technical demands during small-sided football games (4v4 + goalkeeper; SSGs) played on artificial turf and on sand. METHODS: Movement patterns, rating of perceived exertion (RPE) and technical parameters were obtained from eight adult male footballers (20...
September 15, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27617633/toward-dendrite-free-lithium-deposition-via-structural-and-interfacial-synergistic-effects-of-3d-graphene-ni-scaffold
#15
Keyu Xie, Wenfei Wei, Kai Yuan, Wei Lu, Min Guo, Zhihua Li, Qiang Song, Xingrui Liu, Jian-Gan Wang, Chao Shen
Owing to its ultrahigh specific capacity and low electrochemical potential, lithium (Li) metal is regarded as one of the most attractive anode materials for next-generation lithium batteries. Nevertheless, the commercialization of Li-metal-based rechargeable batteries (LiMBs) has been retarded by the uncontrollable growth of Li dendrites, as well as the resulting poor cycle stability and safety hazards. In this work, a 3D graphene@Ni scaffold has been proposed to accomplish dendrite-free Li deposition via structural and interfacial synergistic effects...
October 5, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27613513/a-missense-mutation-in-solute-carrier-family-12-member-1-slc12a1-causes-hydrallantois-in-japanese-black-cattle
#16
Shinji Sasaki, Kiyotoshi Hasegawa, Tomoko Higashi, Yutaka Suzuki, Sumio Sugano, Yasuaki Yasuda, Yoshikazu Sugimoto
BACKGROUND: Hydrallantois is the excessive accumulation of fluid within the allantoic cavity in pregnant animals and is associated with fetal mortality. Although the incidence of hydrallantois is very low in artificial insemination breeding programs in cattle, recently 38 cows with the phenotypic appearance of hydrallantois were reported in a local subpopulation of Japanese Black cattle. Of these, 33 were traced back to the same sire; however, both their parents were reported healthy, suggesting that hydrallantois is a recessive inherited disorder...
2016: BMC Genomics
https://www.readbyqxmd.com/read/27609762/additional-in-series-compliance-reduces-muscle-force-summation-and-alters-the-time-course-of-force-relaxation-during-fixed-end-contractions
#17
Dean L Mayfield, Bradley S Launikonis, Andrew G Cresswell, Glen A Lichtwark
There are high mechanical demands placed on skeletal muscles in movements requiring rapid acceleration of the body or its limbs. Tendons are responsible for transmitting muscle forces, but, because of their elasticity, can manipulate the mechanics of the internal contractile apparatus. Shortening of the contractile apparatus against the stretch of tendon affects force generation according to known mechanical properties; however, the extent to which differences in tendon compliance alter force development in response to a burst of electrical impulses is unclear...
November 15, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27585366/a-method-for-evaluating-timeliness-and-accuracy-of-volitional-motor-responses-to-vibrotactile-stimuli
#18
Matthew J Leineweber, Sam Shi, Jan Andrysek
Artificial sensory feedback (ASF) systems can be used to compensate for lost proprioception in individuals with lower-limb impairments. Effective design of these ASF systems requires an in-depth understanding of how the parameters of specific feedback mechanism affect user perception and reaction to stimuli. This article presents a method for applying vibrotactile stimuli to human participants and measuring their response. Rotating mass vibratory motors are placed at pre-defined locations on the participant's thigh, and controlled through custom hardware and software...
2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27581624/combining-two-open-source-tools-for-neural-computation-biopatrec-and-netlab-improves-movement-classification-for-prosthetic-control
#19
Cosima Prahm, Korbinian Eckstein, Max Ortiz-Catalan, Georg Dorffner, Eugenijus Kaniusas, Oskar C Aszmann
BACKGROUND: Controlling a myoelectric prosthesis for upper limbs is increasingly challenging for the user as more electrodes and joints become available. Motion classification based on pattern recognition with a multi-electrode array allows multiple joints to be controlled simultaneously. Previous pattern recognition studies are difficult to compare, because individual research groups use their own data sets. To resolve this shortcoming and to facilitate comparisons, open access data sets were analysed using components of BioPatRec and Netlab pattern recognition models...
2016: BMC Research Notes
https://www.readbyqxmd.com/read/27532493/effects-of-cognitive-load-and-prosthetic-liner-on-volitional-response-times-to-vibrotactile-feedback
#20
Aman Sharma, Matthew J Leineweber, Jan Andrysek
Artificial tactile feedback systems can improve prosthetic function for people with amputation by substituting for lost proprioception in the missing limb. However, limited data exists to guide the design and application of these systems for mobility and balance scenarios. The purpose of this study was to evaluate the performance of a noninvasive artificial sensory feedback (ASF) system on lower-limb function in the presence of a cognitive load and a liner interface. Reaction times (RTs) and accuracy of leg-movement responses to vibratory stimuli at the thigh were recorded for 12 nondisabled individuals and 3 participants with transfemoral amputation using a custom-built testing apparatus...
2016: Journal of Rehabilitation Research and Development
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