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https://www.readbyqxmd.com/read/27846945/primary-cicatricial-alopecia-other-lymphocytic-primary-cicatricial-alopecias-and-neutrophilic-and-mixed-primary-cicatricial-alopecias
#1
REVIEW
Chantal Bolduc, Leonard C Sperling, Jerry Shapiro
Primary cicatricial alopecias can be frustrating for both patients and physicians. Proper diagnosis guides more successful management of these challenging conditions. Part II will cover the remaining lymphocytic primary cicatricial alopecias, which include pseudopelade of Brocq, central centrifugal cicatricial alopecia, alopecia mucinosa, and keratosis follicularis spinulosa decalvans. It will also discuss the neutrophilic and mixed primary cicatricial alopecias, namely folliculitis decalvans, dissecting cellulitis, folliculitis keloidalis, folliculitis (acne) necrotica, and erosive pustular dermatosis...
December 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27814407/an-unusual-case-of-folliculitis-spinulosa-decalvans
#2
Wenge Fan, Qingsong Zhang, Linyi Song
We report the case of a 24-year-old man who presented with pustules, atrophic scars, and alopecia on the scalp, along with follicular keratotic papules on the cheeks, chest, abdomen, back, lateral upper arms, thighs, and axillae, of 6 years' duration. A diagnosis of folliculitis spinulosa decalvans (FSD) was made based on the clinical manifestation and histopathological findings. Dental examination also revealed dental anomalies and a fissured tongue, which are not known to be related to FSD. We provide an overview of the characteristic findings of FSD as well as a review of previously reported cases...
September 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/27721552/isotretinoin-induced-acute-severe-myopathy-involving-pelvic-girdle-muscles-a-case-report
#3
Farah Sameem, Semira
Oral isotretinoin has been in widespread use for more than three decades. It causes numerous side effects; skin and mucous membrane being commonly involved. Musculoskeletal adverse effects are also known to occur, but pelvic girdle myopathy is rarely reported. We report myopathy involving pelvic girdle muscles in a young male who received oral isotretinoin for folliculitis decalvans.
September 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/27663151/novel-mbtps2-missense-mutation-causes-a-keratosis-follicularis-spinulosa-decalvans-phenotype-mutation-update-and-review-of-the-literature
#4
J Zhang, Y Wang, R Cheng, C Ni, J Liang, M Li, Z Yao
Keratosis follicularis spinulosa decalvans (KFSD) is an X-linked condition characterized by keratotic follicular papules and progressive alopecia, which is caused by mutations in the MBTPS2 gene. We carried out a genetic study on a child who was suspected clinically to have KFSD. Sanger sequencing was performed to detect mutations in the entire coding region of MBTPS2. A novel missense mutation (c.599C>T) was identified in the patient, confirming a diagnosis of KFSD. We reviewed related cases with MBTPS2 mutations for evidence of genotype-phenotype correlations...
October 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27613297/dermoscopy-in-general-dermatology-a-practical-overview
#5
REVIEW
Enzo Errichetti, Giuseppe Stinco
Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. dermatoses presenting with erythematous-desquamative patches/plaques (plaque psoriasis, eczematous dermatitis, pityriasis rosea, mycosis fungoides and subacute cutaneous lupus erythematosus), papulosquamous/papulokeratotic dermatoses (lichen planus, pityriasis rosea, papulosquamous sarcoidosis, guttate psoriasis, pityriasis lichenoides chronica, classical pityriasis rubra pilaris, porokeratosis, lymphomatoid papulosis, papulosquamous chronic GVHD, parakeratosis variegata, Grover disease, Darier disease and BRAF-inhibitor-induced acantholytic dyskeratosis), facial inflammatory skin diseases (rosacea, seborrheic dermatitis, discoid lupus erythematosus, sarcoidosis, cutaneous leishmaniasis, lupus vulgaris, granuloma faciale and demodicidosis), acquired keratodermas (chronic hand eczema, palmar psoriasis, keratoderma due to mycosis fungoides, keratoderma resulting from pityriasis rubra pilaris, tinea manuum, palmar lichen planus and aquagenic palmar keratoderma), sclero-atrophic dermatoses (necrobiosis lipoidica, morphea and cutaneous lichen sclerosus), hypopigmented macular diseases (extragenital guttate lichen sclerosus, achromic pityriasis versicolor, guttate vitiligo, idiopathic guttate hypomelanosis, progressive macular hypomelanosis and postinflammatory hypopigmentations), hyperpigmented maculopapular diseases (pityriasis versicolor, lichen planus pigmentosus, Gougerot-Carteaud syndrome, Dowling-Degos disease, erythema ab igne, macular amyloidosis, lichen amyloidosus, friction melanosis, terra firma-forme dermatosis, urticaria pigmentosa and telangiectasia macularis eruptiva perstans), itchy papulonodular dermatoses (hypertrophic lichen planus, prurigo nodularis, nodular scabies and acquired perforating dermatosis), erythrodermas (due to psoriasis, atopic dermatitis, mycosis fungoides, pityriasis rubra pilaris and scabies), noninfectious balanitis (Zoon's plasma cell balanitis, psoriatic balanitis, seborrheic dermatitis and non-specific balanitis) and erythroplasia of Queyrat, inflammatory cicatricial alopecias (scalp discoid lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia and folliculitis decalvans), nonscarring alopecias (alopecia areata, trichotillomania, androgenetic alopecia and telogen effluvium) and scaling disorders of the scalp (tinea capitis, scalp psoriasis, seborrheic dermatitis and pityriasis amiantacea)...
December 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/27504707/the-diagnosis-and-treatment-of-hair-and-scalp-diseases
#6
Hans Wolff, Tobias W Fischer, Ulrike Blume-Peytavi
BACKGROUND: Hair loss is caused by a variety of hair growth disorders, each with its own pathogenetic mechanism. METHODS: This review is based on pertinent articles retrieved by a selective search in PubMed, on the current German and European guidelines, and on the authors' clinical and scientific experience. RESULTS: Excessive daily hair loss (effluvium) may be physiological, as in the postpartum state, or pathological, due for example to thyroid disturbances, drug effects, iron deficiency, or syphilis...
May 27, 2016: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/27051769/substance-p-in-keratosis-follicularis-spinulosa-decalvans
#7
Isabella Doche, Maria Hordinsky, George L Wilcox, Neusa S Valente, Ricardo Romiti
No abstract text is available yet for this article.
November 2015: JAAD Case Reports
https://www.readbyqxmd.com/read/26773616/leprosy-in-the-bible
#8
Andrzej Grzybowski, Małgorzata Nita
For many years, the biblical term tzaraat has referred to leprosy. In fact, the disease or diseases described under this name have no relationship to leprosy, as it was known in the Middle Ages or today; moreover, the term referred not only to skin disease, but also to the state of the ritual impurity and punishment for the sins. Although the real nature of tzaraat remains unknown, the differential diagnosis might include the following: Psoriasis, seborrheic dermatitis, favus, dermatophyte infections, nummular dermatitis, atopic dermatitis, pityriasis rosea, crusted scabies, syphilis, impetigo, sycosis barbae, alopecia areata, furuncles, scabies, neurodermatitis, scarlet fever, lupus erythematosus, lichen sclerosus et atrophicus, folliculitis decalvans, morphea, sarcoidosis, and lichen planopilaris...
January 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/26691243/multiple-secondary-cutaneous-osteomas-in-a-patient-with-folliculitis-decalvans
#9
B Monteagudo, A Varela-Veiga, J Á Vázquez-Bueno, A M Porta
No abstract text is available yet for this article.
April 2016: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/26622157/keratosis-follicularis-spinulosa-decalvans-a-report-of-three-cases
#10
Dipali D Malvankar, S Sacchidanand
Keratosis follicularis spinulosa decalvans is a disorder affecting the hair follicles characterized by scarring alopecia of the scalp, eyebrows, and axillae, sometimes associated with photophobia and keratoderma. Being X-linked, it is more commonly seen in males but can be rarely seen in females also. We report three cases of this rare disorder including one in a female.
July 2015: International Journal of Trichology
https://www.readbyqxmd.com/read/26622153/clinical-trichoscopic-and-histopathological-features-of-primary-cicatricial-alopecias-a-retrospective-observational-study-at-a-tertiary-care-centre-of-north-east-india
#11
Binod Kumar Thakur, Shikha Verma, Vandana Raphael
BACKGROUND: The primary cicatricial alopecias (PCAs) are a rare group of diseases where hair follicle is the primary target of destruction. There are a few studies on histopathological and trichoscopic features of PCA. AIMS: To study the clinical, trichoscopic, and histopathological characteristics of PCAs of the scalp and to find out the concordance between trichoscopic and histopathological diagnosis. MATERIALS AND METHODS: We retrospectively analyzed the clinical, trichoscopic, and histopathological features of 24 PCA patients...
July 2015: International Journal of Trichology
https://www.readbyqxmd.com/read/26428395/-scalp-folliculitis-dissequans-or-decalvans
#12
EDITORIAL
B Matard
No abstract text is available yet for this article.
November 2015: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/26400479/treatment-of-folliculitis-decalvans-using-intensity-modulated-radiation-via-tomotherapy
#13
COMPARATIVE STUDY
Khaled Elsayad, Jan Kriz, Uwe Haverkamp, Kerasia-Maria Plachouri, Antonia Jeskowiak, Cord Sunderkötter, Hans Theodor Eich
BACKGROUND: Folliculitis decalvans (FD) is a form of primary neutrophilic scarring alopecia that is characterized clinically by chronic suppurative folliculitis and often associated with pruritus or even pain. Treatment of FD is often difficult. Herein, we report a case of recalcitrant and painful folliculitis decalvans refractory to antibiotic and anti-inflammatory therapies, which was successfully treated by intensity-modulated radiotherapy (IMRT) in order to irreversibly eliminate hair follicles that prove to be one etiological trigger...
November 2015: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/26383761/-drug-treatment-of-alopecia
#14
H Wolff
BACKGROUND: Alopecia is the term used to describe hairless areas of the scalp. They can follow a specific pattern, be diffuse or circumscript. Androgenetic alopecia (AGA) follows a pattern: in men thinning of temples and vertex up to total baldness; in women thinning of the midline or parietal area. CAUSES: Lack of iron or cytostatic drugs cause diffuse alopecia, while in autoimmune diseases such as alopecia areata or lichen planus bizarre shapes of hairless areas are observed...
October 2015: Der Internist
https://www.readbyqxmd.com/read/26370646/primary-scarring-alopecias
#15
REVIEW
Dimitrios Rigopoulos, Gregoriou Stamatios, Dimitrios Ioannides
Scarring alopecia or cicatricial alopecia results from follicular damage that is sufficient to cause the destruction and replacement of pilosebaceous structures by scar tissue. Primary scarring alopecias represent a group of disorders that primarily affect the hair follicles, as opposed to secondary scarring alopecias, which affect the dermis and secondarily cause follicular destruction. Inflammation may predominantly involve lymphocytes or neutrophils. Cicatricial alopecias that mainly involve lymphocytic inflammation include discoid lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, central centrifugal alopecia, and pseudopelade (Brocq)...
2015: Current Problems in Dermatology
https://www.readbyqxmd.com/read/26203471/contact-dermatitis-masquerading-as-folliculitis-decalvans-methylisothiazolinone-strikes-again
#16
Olivier Aerts, Frederic Van Dyck, Julie Dandelooy, Tine Mellaerts, Julien Lambert
No abstract text is available yet for this article.
September 2014: Dermatitis
https://www.readbyqxmd.com/read/26086412/the-practical-usefulness-of-dermoscopy-in-general-dermatology
#17
REVIEW
E Errichetti, G Stinco
Beside to traditional use, dermoscopy is more and more used in the assessment of other "general" dermatologic conditions, namely scalp and hair disorders (trichoscopy), nails abnormalities (onychoscopy), skin infections and infestations (entomodermoscopy), and cutaneous inflammatory diseases (inflammoscopy). Among the list of new applications of dermoscopy, the study of inflammatory dermatoses is probably the most promising topic in terms of development and usefulness, considering the large number of such disorders and the frequent problems in their differential diagnosis which the dermatologist encounters in own daily clinical practice...
October 2015: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/25798695/intravenous-human-immunoglobulin-for-treatment-of-folliculitis-decalvans
#18
Nuriah Ismail, Nicola Ralph, Gillian Murphy
We report a case of folliculitis decalvans (FD) successfully treated with intravenous human immunoglobulin (HIG). Many conventional treatments with topical agents and oral antibiotics had failed to achieve disease remission, treatment with HIG at a dose of 2 g/kg for the first month, reduced to 1 g/kg for second to fourth months was therefore started, which resulted in rapid improvement and ultimately complete resolution of FD. Clinical improvement was noted after the first infusion of HIG and remission of inflammation was achieved after the fourth infusion...
October 2015: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/25775663/retrospective-review-of-folliculitis-decalvans-in-23-patients-with-course-and-treatment-analysis-of-long-standing-cases
#19
M J Kristine Bunagan, Nusrat Banka, Jerry Shapiro
BACKGROUND: To date, there is no standard treatment of folliculitis decalvans (FD), a rare type of cicatricial alopecia. OBJECTIVE AND METHODS: The records of 23 patients with FD (1998-2012) were retrospectively analyzed, with added data review on the course and treatment of long-standing cases. RESULTS: Initial management consisted mostly of intralesional triamcinolone acetonide, clobetasol lotion, and either cephalexin, minocycline, doxycycline, or tetracycline...
January 2015: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/25731720/off-label-use-of-tnf-alpha-inhibitors-in-a-dermatological-university-department-retrospective-evaluation-of-118-patients
#20
Freja Lærke Sand, Simon Francis Thomsen
Tumor necrosis factor-alpha (TNF)-alpha inhibitors are licensed for patients with severe refractory psoriasis and psoriatic arthritis. However, TNF-alpha inhibitors have also been used off-label for various recalcitrant mucocutaneous diseases. This study aimed to evaluate the efficacy and safety of TNF-alpha inhibitors used for off-label dermatological indications. We retrospectively evaluated patient records of 118 patients treated off-label with TNF-alpha inhibitors in a dermatological university department...
May 2015: Dermatologic Therapy
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