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https://www.readbyqxmd.com/read/29156091/multifarious-anchovy-and-sardine-regimes-in-the-humboldt-current-system-during-the-last-150-years
#1
Renato Salvatteci, David Field, Dimitri Gutierrez, Tim Baumgartner, Vicente Ferreira, Luc Ortlieb, Abdel Sifeddine, Daniel Grados, Arnaud Bertrand
The Humboldt Current System (HCS) has the highest production of forage fish in the world, though it is highly variable and the future of the primary component, anchovy, is uncertain in the context of global warming. Paradigms based on late 20(th) century observations suggest that large-scale forcing controls decadal-scale fluctuations of anchovy and sardine across different boundary currents of the Pacific. We develop records of anchovy and sardine fluctuations since 1860 AD using fish scales from multiple sites containing laminated sediments and compare them with Pacific basin-scale and regional indices of ocean-climate variability...
November 20, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29155921/aridification-as-a-driver-of-biodiversity-a-case-study-for-the-cycad-genus-dioon-zamiaceae
#2
José Said Gutiérrez-Ortega, Takashi Yamamoto, Andrew P Vovides, Miguel Angel Pérez-Farrera, José F Martínez, Francisco Molina-Freaner, Yasuyuki Watano, Tadashi Kajita
Background and Aims: Aridification is considered a selective pressure that might have influenced plant diversification. It is suggested that plants adapted to aridity diversified during the Miocene, an epoch of global aridification (≈15 million years ago). However, evidence supporting diversification being a direct response to aridity is scarce, and multidisciplinary evidence, besides just phylogenetic estimations, is necessary to support the idea that aridification has driven diversification...
November 16, 2017: Annals of Botany
https://www.readbyqxmd.com/read/29155747/isolation-of-salmonella-typhimurium-containing-phagosomes-from-macrophages
#3
Saray Gutiérrez, Martina Wolke, Georg Plum, Nirmal Robinson
Salmonella typhimurium is a facultative intracellular bacterium that causes gastroenteritis in humans. After invasion of the lamina propria, S. typhimurium bacteria are quickly detected and phagocytized by macrophages, and contained in vesicles known as phagosomes in order to be degraded. Isolation of S. typhimurium-containing phagosomes have been widely used to study how S. typhimurium infection alters the process of phagosome maturation to prevent bacterial degradation. Classically, the isolation of bacteria-containing phagosomes has been performed by sucrose gradient centrifugation...
October 25, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29155379/women-break-an-engineering-barrier-while-other-engineering-disciplines-stumble-bme-represents-a-success-story-in-attracting-american-women-to-a-male-dominated-field
#4
Claudia Gutierrez, Meaghan Paulosky, Angeline Aguinaldo, Jackie Gerhart
While the field of engineering as a whole is largely male-dominated, biomedical engineering (BME) is one area poised to overturn this trend. Women in the United States were awarded only 20% of all engineering B.S. degrees in 2015; in BME, however, 40.9% of the degree recipients were women. This stands in stark contrast to the more traditional fields of mechanical and electrical engineering, where women were awarded just 13.2% and 12.5% of B.S. degrees, respectively. This trend toward more female participation in BME continues at both the M...
November 2017: IEEE Pulse
https://www.readbyqxmd.com/read/29155337/photodynamic-therapy-in-fibrosarcoma-balb-c-animal-model-observation-of-the-rebound-effect
#5
Etcheverry María Eugenia, Pasquale Miguel Ángel, Gutiérrez Anabella, Bibé Solange, Ponzinibbio Carlos, Poteca Horacio, Garavaglia Mario
In vivo spectrofluorometric analysis during photodynamic therapy (PDT) is a fundamental tool to obtain information about the drug bleaching kinetics. Using a portable spectrofluorometer with an excitation source emitting at 400nm wavelength and a spectral analyzer ranging from 500nm to 800nm, the evolution of the meta-tetra(hydroxyphenyl) chlorin (m-THPC) photosensitizer fluorescence spectrum at the tumoral tissue of BALB/c murines with fibrosarcoma located at their flank was followed up. Ex vivo fluorescence measurements of the tumor and skin were also performed with the aim of better characterizing the in vivo signal at different parts of the tumor...
November 16, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29154544/insights-into-the-mechanism-of-ground-and-excited-state-double-proton-transfer-reaction-in-formic-acid-dimer
#6
Santanab Giri, Rakesh Parida, Madhurima Jana, Soledad Gutierrez-Oliva, Alejandro Toro-Labbé
The mechanism of ground and excited state double proton transfer reaction in formic acid dimer has been analyzed with the help of reaction force and the reaction electronic flux. The separation of reaction electronic flux in terms of electronic activity and reactivity, NBO, dual descriptor lends additional support for the mechanism. Interestingly we found that, the ground state double proton transfer mechanism is concerted synchronic, whereas the excited state double proton transfer is concerted asynchronic in nature...
November 20, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29154427/design-of-a-multicentre-randomized-controlled-trial-to-assess-the-safety-and-efficacy-of-dose-titration-by-specialized-nurses-in-patients-with-heart-failure-etific-study-protocol
#7
Juana Oyanguren, LLuisa García-Garrido, Magdalena Nebot Margalef, Iñaki Lekuona, Josep Comin-Colet, Nicolás Manito, Julia Roure, Pilar Ruiz Rodriguez, Cristina Enjuanes, Pedro Latorre, Jesús Torcal Laguna, Susana García-Gutiérrez
AIMS: Heart failure (HF) is associated with many hospital admissions and relatively high mortality, rates decreasing with administration of beta-blockers (BBs), angiotensin-converting-enzyme inhibitors, angiotensin II receptor blockers, and mineralocorticoid receptor antagonists. The effect is dose dependent, suboptimal doses being common in clinical practice. The 2012 European guidelines recommend close monitoring and dose titration by HF nurses. Our main aim is to compare BB doses achieved by patients after 4 months in intervention (HF nurse-managed) and control (cardiologist-managed) groups...
November 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29153640/-analysis-of-the-use-of-proton-pump-inhibitors-in-primary-health-care
#8
M J Hernández-Arroyo, A Díaz-Madero, E Enríquez-Gutiérrez, M C Teijeiro-Bermejo, E Sáez-Rodríguez, M R Gutiérrez-Martín
OBJECTIVE: The increase in the consumption of anti-ulcer drugs is accompanied by a high rate of incorrect use. The objectives of this study were to analyse the adequacy of repeat prescriptions of proton pump inhibitors (PPIs) in a Medical Centre, and to evaluate the efficacy of an improvement intervention. MATERIAL AND METHOD: A cross-sectional, descriptive and observational study of prevalence was conducted on patients in a medical centre under treatment with PPIs for at least 3consecutive months (November 2016-January 2017)...
November 15, 2017: Semergen
https://www.readbyqxmd.com/read/29153530/physicochemical-and-sensory-properties-of-yogurts-containing-sacha-inchi-plukenetia-volubilis-l-seeds-and-%C3%AE-glucans-from-ganoderma-lucidum
#9
Ana-Milena Vanegas-Azuero, Luis-Felipe Gutiérrez
Dairy products have been widely used for adding various biomolecules with the aim of improving their functional properties and health benefits. In this study, the physicochemical properties and sensory acceptance of yogurts enriched with sacha inchi (Plukenetia volubilis) seeds (SIS) and β-glucans from Ganoderma lucidum (BGGL) were investigated. The angiotensin-converting enzyme-inhibitory activity of some yogurt samples was also evaluated. Yogurts were produced from reconstituted skim milk powder, and SIS (4% wt/wt) and BGGL were added at different concentrations (0-1...
November 15, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29152913/the-relationship-of-socioeconomic-status-with-body-mass-index-depends-on-the-socioeconomic-measure-used
#10
Ana Basto-Abreu, Tonatiuh Barrientos-Gutiérrez, Rodrigo Zepeda-Tello, Vanessa Camacho, David Gimeno Ruiz de Porras, Mauricio Hernández-Ávila
OBJECTIVE: The association between socioeconomic status (SES) and body mass index (BMI) in middle-income countries is mixed. Heterogeneity in SES indicators used could explain some differences. This study aimed to identify SES indicators consistently associated with BMI in Mexican adults in 2006, 2012, and 2016. METHODS: Data were obtained from the Mexican National Health and Nutrition Surveys of 2006, 2012, and 2016, including adults 20 to 59 years old. Given expected differences by sex, sex-stratified linear regression models were fitted for each survey...
November 20, 2017: Obesity
https://www.readbyqxmd.com/read/29152323/new-melanocortin-like-peptide-of-e-coli-can-suppress-inflammation-via-the-mammalian-melanocortin-1-receptor-mc1r-possible-endocrine-like-function-for-microbes-of-the-gut
#11
Xiaoling Qiang, Anthony S Liotta, Joseph Shiloach, J C Gutierrez, Haichao Wang, Mahendar Ochani, Kanta Ochani, Huan Yang, Aviva Rabin, Derek LeRoith, Maxine A Lesniak, Markus Böhm, Christian Maaser, Klaus Kannengiesser, Mark Donowitz, Shervin Rabizadeh, Christopher J Czura, Kevin J Tracey, Mark Westlake, Aida Zarfeshani, Syed F Mehdi, Ann Danoff, Xueliang Ge, Suparna Sanyal, Gary J Schwartz, Jesse Roth
E. coli releases a 33 amino acid peptide melanocortin-like peptide of E. coli (MECO-1) that is identical to the C-terminus of the E. coli elongation factor-G (EF-G) and has interesting similarities to two prominent mammalian melanocortin hormones, alpha-melanocyte-stimulating hormone (alpha-MSH) and adrenocorticotropin (ACTH). Note that MECO-1 lacks HFRW, the common pharmacophore of the known mammalian melanocortin peptides. MECO-1 and the two hormones were equally effective in severely blunting release of cytokines (HMGB1 and TNF) from macrophage-like cells in response to (i) endotoxin (lipopolysaccharide) or (ii) pro-inflammatory cytokine HMGB-1...
2017: NPJ Biofilms and Microbiomes
https://www.readbyqxmd.com/read/29151860/dose-dependent-selection-drives-lineage-replacement-during-the-experimental-evolution-of-sdhi-fungicide-resistance-in-zymoseptoria%C3%A2-tritici
#12
Omar Gutiérrez-Alonso, Nichola J Hawkins, Hans J Cools, Michael W Shaw, Bart A Fraaije
Fungicide resistance is a constant threat to agricultural production worldwide. Molecular mechanisms of fungicide resistance have been studied extensively in the wheat pathogen Zymoseptoria tritici. However, less is known about the evolutionary processes driving resistance development. In vitro evolutionary studies give the opportunity to investigate this. Here, we examine the adaptation of Z. tritici to fluxapyroxad, a succinate dehydrogenase (Sdh) inhibitor. Replicate populations of Z. tritici derived from the sensitive isolate IPO323 were exposed to increasing concentrations of fluxapyroxad with or without UV mutagenesis...
December 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/29151361/magnesium-sulfate-and-ophthalmic-artery-doppler-velocimetry-in-patients-with-severe-preeclampsia-a-case-series
#13
Cristiane Alves Oliveira, Renato Augusto Moreira de Sa, Karina Vieira Zamprogno, Fabio Gutierrez da Matta, Flávia do Vale Araújo
BACKGROUND: In the present study, we used Doppler velocimetry in the ophthalmic artery to evaluate the hemodynamic status of the intracranial vasculature. This is the first time in the literature that indices of ophthalmic artery Doppler sonography of women with preeclampsia were evaluated before and after the use of magnesium sulfate to prevent eclampsia. CASE PRESENTATION: Indices of ophthalmic artery Doppler sonography of six women with severe preeclampsia at 27 to 33 weeks of gestational age were evaluated before and after the use of magnesium sulfate (10 minutes, 30 minutes, and 60 minutes after the magnesium sulfate loading dosage...
November 20, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29151179/comparison-of-three-analgesic-drug-regimens-with-twelfth-subcostal-nerve-block-for-pain-control-during-extracorporeal-shock-wave-lithotripsy
#14
Miguel Maldonado-Avila, Leopoldo Mateo Garduño-Arteaga, Roberto Alejandro Vela-Mollinedo, Jorge Jaspersen-Gastelum, Francisco Virgen-Gutierrez, Marcos Del Rosario-Santiago, Victor Rios-Davila
INTRODUCTION AND OBJECTIVE: Extracorporeal shock wave lithotripsy (ESWL) is the first-line treatment in the majority of cases of upper urinary tract stones. Since its introduction, attempts have been made to establish the ideal accompanying analgesic method to enable the application of shock waves of adequate duration and intensity for efficacious stone fragmentation. An open, randomized, prospective, longitudinal, comparative, and experimental clinical study was conducted to evaluate the efficacy of subcostal nerve block with lidocaine, comparing it in combination with tramadol or diclofenac for pain control during ESWL...
November 18, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29150218/keratitis-secondary-to-fusarium-spp-in-spain-2012-2014
#15
M A Mosquera Gordillo, N Barón Cano, A Garralda Luquin, C López Gutiérrez, E Mengual Verdú, G Trujillo Cabrera, J M Garrido Fierro, J Lamarca Mateu, J C Sánchez España, P Marticorena Álvarez, R Feijoó Lera, S Martín Nalda, T Marti Huguet, V Gacía Conca
OBJECTIVE: To describe the clinical-epidemiological characteristics of a case series of fungal keratitis associated with Fusarium spp.., in Spain during the years 2012 to 2014. METHODS: A retrospective study of a case series was conducted on a systematic random sample of 10% of patients identified in Health Centres of provincial capitals (n=250). The centres were asked whether they had been presented with cases of Fusarium spp. keratitis characterised by microbiological methods...
November 14, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29150104/high-frequency-of-primary-refractory-disease-and-low-progression-free-survival-rate-of-hodgkin-s-lymphoma-a-decade-of-experience-in-a-latin-american-center
#16
José Carlos Jaime-Pérez, Carmen Magdalena Gamboa-Alonso, José Ramón Padilla-Medina, Raúl Alberto Jiménez-Castillo, Leticia Alejandra Olguín-Ramírez, César Homero Gutiérrez-Aguirre, Olga Graciela Cantú-Rodríguez, David Gómez-Almaguer
BACKGROUND: Reports dealing with clinical outcomes of classical Hodgkin's lymphoma in low- to middle-income countries are scarce and response to therapy is poorly documented. This report describes the characteristics and clinical outcomes of patients with classical Hodgkin's lymphoma from a single institution in Latin America. METHOD: A retrospective study was conducted over ten years of patients with classical Hodgkin's lymphoma treated at a referral center. Progression-free and overall survival rates were estimated by Kaplan-Meier analysis...
October 2017: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/29149111/-bilateral-bronchopneumonia-due-to-rothia-mucilaginosa
#17
B De Escalante Yangüela, A Gracia Gutiérrez, B C Gracia Tello, V A Alastrué Del Castaño, E Bueno Juana, S Algárate Cajo
Rothia mucilaginosa (R. mucilaginosa), formerly named Stomatococcus mucilaginosus, is a facultatively anaerobic, encapsulated gram-positive coccus, which forms part of the normal oropharyngeal and is rarely considered to be a pathogen in immunocompetent patients, although it can produce, on rare occasions, serious infections like bacteremia, endocarditis and respiratory infections; such as pneumonia, pleural empyema or superinfection of bronchiectasis. We present the case of a 74-year-old male diagnosed with right basal pneumonia of torpid evolution with a poor initial response to different antibiotics, with clinical and radiological worsening and the appearance of bilateral bronchopneumonia with pseudonodular images...
November 17, 2017: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/29148967/group-b-streptococcus-infections-caused-by-improper-sourcing-and-handling-of-fish-for-raw-consumption-singapore-2015-2016
#18
Man L Chau, Swaine L Chen, Min Yap, Sri H P Hartantyo, Paul K T Chiew, Charlene J Fernandez, Wai K Wong, Rockey K Fong, Wei L Tan, Brian Z Y Tan, Youming Ng, Kyaw T Aung, Kurosh S Mehershahi, Christopher Goh, Joanne S L Kang, Timothy Barkham, Adeline O K Leong, Ramona A Gutiérrez, Lee C Ng
We assessed microbial safety and quality of raw fish sold in Singapore during 2015-2016 to complement epidemiologic findings for an outbreak of infection with group B Streptococcus serotype III sequence type (ST) 283 associated with raw fish consumption. Fish-associated group B Streptococcus ST283 strains included strains nearly identical (0-2 single-nucleotide polymorphisms) with the human outbreak strain, as well as strains in another distinct ST283 clade (57-71 single-nucleotide polymorphisms). Our investigations highlight the risk for contamination of freshwater fish (which are handled and distributed separately from saltwater fish sold as sashimi) and the need for improved hygienic handling of all fish for raw consumption...
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29148135/cadence-tracking-and-disturbance-rejection-in-functional-electrical-stimulation-cycling-for-paraplegic-subjects-a-case-study
#19
Lucas O da Fonseca, Antônio P L Bó, Juliana A Guimarães, Miguel E Gutierrez, Emerson Fachin-Martins
Functional electrical stimulation cycling has been proposed as an assistive technology with numerous health and fitness benefits for people with spinal cord injury, such as improvement in cardiovascular function, increase in muscular mass, and reduction of bone mass loss. However, some limitations, for example, lack of optimal control strategies that would delay fatigue, may still prevent this technology from achieving its full potential. In this work, we performed experiments on a person with complete spinal cord injury using a stationary tadpole trike when both cadence tracking and disturbance rejection were evaluated...
November 2017: Artificial Organs
https://www.readbyqxmd.com/read/29147717/the-role-of-hierarchical-design-and-morphology-in-the-mechanical-response-of-diatom-inspired-structures-via-simulation
#20
Alejandro Gutiérrez, Metin G Guney, Gary K Fedder, Lilian P Dávila
Diatoms are microscopic algae with intricate shell morphologies and features ranging from the nanometer to the micrometer scale, which have been proposed as templates for drug delivery carriers, optical devices, and metamaterials design. Several studies have found that diatom shells show unique mechanical properties such as high specific strength and resilience. One hypothesis is that these properties stem from the structural arrangement of the material at the nanometer and micrometer length scales, challenging the concept between what constitutes a "material" versus a "structure"...
November 17, 2017: Biomaterials Science
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